Abstract: A device and method are provided for monitoring access to a patient by a device that withdraws liquid from the patient and/or supplies liquid to the patient, via a flexible line. A vessel access can be monitored during an extracorporeal blood treatment for which the blood of a patient is withdrawn via a flexible arterial line having an arterial puncture cannula, and supplied to the patient via a flexible venous line having a venous puncture cannula. The monitoring device has a line guide for loosely guiding a line segment of the flexible line. By detecting a change in situation of the loosely guided line segment, a conclusion is made as to whether an incorrect vessel access has occurred.

Abstract: A packaging assembly comprises a case configured to contain at least one injection device for delivering a medicament; a cooling unit configured to lower an internal temperature of the case; a processing arrangement; a device sensor configured to detect at least one injection device contained within the case, and to receive device storage information from the at least one detected injection device; and a data storage device. The processing arrangement is configured to record an injection history on the data storage device. The processor arrangement is configured to control the cooling unit to set an internal temperature of the case according to the received device storage information.

Abstract: A needle syringe has a plunger and a needle for filling and dispensing liquid from the cavity. The cavity has finger clip with movable locking pins. The plunger has at least one set of grooves corresponding to a specific dosage for the needle syringe, the specific dosage of the groove being demarked by a marking ledge that indicates a change to a deeper depth section of the groove. The locking pins are configured to rest in the at least one set of grooves, such that when the plunger is removed, the locking pins pass within a first shallow section of the groove, pass over the ledge, and continue to pass in the deeper depth section of the groove. When the plunger is depressed in a first partial dispensing movement, the locking pins pass in the deeper depth section of the groove until the plunger depression is temporarily locked when the locking pins reach the ledge, where the dose remaining in the cavity is the specific dosage.

Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: A medication delivery device and/or dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having a dose setting system and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge.

Abstract: The present disclosure relates to a medication delivery device having a dose detection system and an associated control system configured to determine an amount of medication delivered from the medication delivery device based on the sensing of relative rotation within the medication delivery device. The relative rotation may occur between a dose setting member and an actuator and/or housing of the medication delivery device. The rotation sensing may involve piezoelectric sensing, more specifically repeatedly deforming a piezoelectric sensor with a mechanical force. The dose detection system may be a modular or integral component of the medication delivery device.

Abstract: The present disclosure relates to a drug delivery device, having a longitudinal axis and comprising a plunger movable along the longitudinal axis and a guide curve adapted to engage at least one part of the plunger so as to guide the plunger when the plunger is being released to move along the longitudinal axis.

Abstract: Embodiments described herein generally relate to devices, systems and methods for measuring the dose remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a plurality of light sources which are disposed and configured to emit electromagnetic radiation toward the container. A plurality of sensors are located in the apparatus that are optically coupleable to the plurality of light sources and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light sources. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.

Abstract: A system comprises a first member, a second member, and a third member, wherein the first and second members are rotatable relative to the third member, wherein the first and second members are coupled to one another by a dead-angle follower coupling, wherein the dead-angle follower coupling is configured such that the first and second members are rotatable relative to one another, wherein the second and third members are rotationally coupled to one another by a switchable coupling mechanism, wherein the switchable coupling mechanism is switchable between two different states, a locked state and a non-locked state, wherein the maximum torque transferable between the second and third members via the switchable coupling mechanism in the locked state is greater than in the non-locked state, wherein the switchable coupling mechanism is in the locked state when the first member is in a locking position relative to the second member.

Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.

Abstract: A compression device for freeing a ring trapped on a digit includes a rigid outer body. The rigid outer body includes a digit cavity extending from a cavity opening at a body proximal end of the body towards a body distal end of the body, a fluid inlet, and a fluid flow path fluidly connecting the fluid inlet to one or more inflation chambers positioned in the digit cavity. The body proximal end includes an upper portion, a lower portion, and two laterally spaced-apart side portions. At least one side portion is distally recessed as compared to the upper and lower portions to accommodate an interdigital fold. At least one flexible bladder lines the digit cavity, each flexible bladder defining at least one wall of one of the one or more inflation chambers.

Abstract: The present invention relates to a drive mechanism for a drug delivery device, comprising: a piston rod to operably engage with a piston of a cartridge to displace the piston in a distal direction during a dose dispensing action, at least one actuation member mechanically coupled with the piston rod to induce a distally directed displacement of the piston rod when actuated by a user, a control to ascertain at least one predefined condition of use, and at least one interlock member coupled with the control to mechanically obstruct displacement of the piston rod if the condition of use is not fulfilled.

Abstract: A method of providing and/or injecting octreotide acetate to a subject in need thereof includes storing the octreotide acetate in a cartridge of a multi-use multi-dose injector provided with a variable dose setter and actuator. The injector includes a needle configured for subcutaneous administration of the octreotide acetate, the octreotide acetate having a concentration of 2,500 ?g/mL. The method further includes providing, on the injector, a plurality of indicia only at prescribed doses of 50 ?g, 100 ?g, 150 ?g and 200 ?g settable via the dose setter without indicia between said prescribed doses; and permitting setting of a dose of the octreotide acetate by rotation of the variable dose setter, wherein the injector is configured to provide at least one audible feedback during the rotation.

Abstract: A dosage sensing module for or in a pen drug delivery device and comprising a power source unit, a processor unit and a dosage sensor unit with a first sensor part adapted to be fixed to a part not rotating during dose expelling and comprising a flexible printed circuit board sheet on which a pattern of individual electrical conductive sensor areas are arranged. The sensor unit further comprises a second sensor part adapted to be fixed to the piston rod to follow the rotation thereof during dose expelling. The second sensor part comprises individual structures that together with the conductive sensor areas are adapted to, upon relative rotational movement between the first and second sensor part, provide electrical signals to a processor unit indicative of the relative rotational position between the first and second sensor part.

Abstract: A sliding cover for a liquid delivery device, such as a cap (100) for a pen injector (200), incorporates a set of sensors including an optical sensor (110) with an output which changes during uncapping or capping motions on passing of a plunger (220) of the pen injector. This output is used together with a position sensor (120) to determine the position of the plunger along a cylinder (210) of the liquid delivery device. By monitoring changes in the plunger position, the quantity of dosages delivered by the liquid delivery device can be determined, displayed, stored and/or transmitted to an external device for further data processing or storage. Preferred implementations of the invention employ optical sensors with a converging beam (115), and/or position sensors employing linear potentiometer strips (132).

Abstract: A dosing mechanism for an injection device includes a dose-setting element with a first element coupled thereto, which, during dose setting, is rotatable relative to a second element about a main rotation axis in a first direction and, during dose discharge, is fixed in rotation relative to the second element. The first and the second elements are coupled via a sleeve-shaped stop element, which forms a stop abutment. The dosing mechanism includes a stop, and the stop abutment, during the rotation of the first element in the first direction, executes a movement to a stop position where the stop abutment strikes the stop and prevents rotation of the first element relative to the second element in the first direction of rotation. The sleeve-shaped stop element is rotatable about a secondary rotation axis, which is offset parallel to or offset at an angle to the main rotation axis.

Abstract: A drug delivery device includes a housing and a movable member, which is arranged to be rotatable in an incrementing direction and a decrementing direction, the movable member being operatively coupled to an energy storage member and biased to rotate into the decrementing direction by energy stored or storable in the energy storage member. Rotation of the movable member in the incrementing direction increases the energy stored in the energy storage member. The drug delivery device also includes a locking system including a locking feature, a block feature, and a release member, wherein the locking feature is arranged to cooperate with the block feature to form a releasable locking interface configured such that, when the releasable locking interface is established, rotational movement of the movable member relative to the housing is blocked in the decrementing direction, and when the releasable locking interface is released, the movable member is rotatable in the decrementing direction.

Abstract: A liquid medicine administration device includes a prefilled syringe and a gasket biasing member assembly. The biasing member assembly includes: a gasket pressing member configured to press a gasket; a flange attachment member attached to the prefilled syringe; a biasing member housed between the pressing member and the flange attachment member; and an operating member including an engagement holding portion. The pressing member includes an engagement portion to be engaged with the flange attachment member. When the engagement holding portion is located at an abutment position, deformation of a deformable portion is inhibited by abutment between the engagement holding portion and an abutment portion of a deformable portion, and engagement between the engagement portion and the attachment member body portion is held.

Abstract: A system comprises a first member, a second member, and a third member, wherein the first and second members are rotatable relative to the third member, wherein the first and second members are coupled to one another by a dead-angle follower coupling, wherein the dead-angle follower coupling is configured such that the first and second members are rotatable relative to one another, wherein the second and third members are rotationally coupled to one another by a switchable coupling mechanism, wherein the switchable coupling mechanism is switchable between two different states, a locked state and a non-locked state, wherein the maximum torque transferable between the second and third members via the switchable coupling mechanism in the locked state is greater than in the non-locked state, wherein the switchable coupling mechanism is in the locked state when the first member is in a locking position relative to the second member.

Abstract: A drug delivery device includes a housing and a movable member, which is arranged to be rotatable in an incrementing direction and a decrementing direction, the movable member being operatively coupled to an energy storage member and biased to rotate into the decrementing direction by energy stored or storable in the energy storage member. Rotation of the movable member in the incrementing direction increases the energy stored in the energy storage member. The drug delivery device also includes a locking system including a locking feature, a block feature, and a release member, wherein the locking feature is arranged to cooperate with the block feature to form a releasable locking interface configured such that, when the releasable locking interface is established, rotational movement of the movable member relative to the housing is blocked in the decrementing direction, and when the releasable locking interface is released, the movable member is rotatable in the decrementing direction.

Abstract: An auto-injector for administering a dose of a liquid medicament includes an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), operating the syringe to supply the dose of medicament (M), and retracting the syringe with the needle into the covered position. After delivering the medicament, an activator arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection.

Abstract: A drug delivery device comprising: a housing; a cylindrical member rotatably supported within the housing; and a plurality of sensors; wherein: the outer surface of the cylindrical member is provided with a single track, the track forming an encoder and having a plurality of first track segments and a plurality of second track segments arranged along the length of the track which are respectively capable of inducing first and second responses in the sensors; and in each rotational position of the cylindrical member relative to the housing at least one different first track segment is capable of inducing a first response in at least one said sensor, thereby enabling the rotational position of the cylindrical member relative to the housing to be determined.

Abstract: Methods for using precision low-dose, low-waste syringe configurations, which may have a reduced diameter lumen for dispensing 0.01 ml increments of contents. Methods may employ ergonomic attachments that improve the control and precision of the syringe. An attachment main body includes a gripping surface to permit a user to engage the attachment and move the attachment main body, and thus the syringe plunger relative to the syringe barrel using sliding movement. Methods may employ an assist feature on the attachment, which may be a traction wheel. Methods for using syringes with contents of higher viscosity may employ a pair of toothed pinion gears on a wheel and which cooperate with respective toothed racks formed on or fastened to the syringe body.

Abstract: An apparatus and method for adjusting an injection device for administering a substance that includes a device housing with an array of fastening points. The apparatus has at least two housing-like shells, each having at least one holding device and at least one blocking device for attaching to the housing. The holding device of a first shell can be attached to a fastening point, and the holding device of a second shell can be attached to a further fastening point. Upon attaching all of the plurality of housing-like shells to the housing, the blocking devices of the plurality of housing-like shells prevent the disengagement of the plurality of housing-like shells from the housing by blocking detachment of the holding devices from the fastening points. At least one of the housing-like shells comprises an electronic assembly and shell attachment to the housing activates the electronic assembly.

Abstract: The present disclosure relates to a dose detection system for use with a medication delivery device in which a dose setting member rotates relative to an actuator during dose delivery. The dose detection system comprises a module including a rotation sensor attached to the actuator during dose delivery. A sensed element is attached to the dose setting member and includes first gear teeth. The rotation sensor comprises a driven gear including second gear teeth. The second gear teeth are operatively received by the first gear teeth and are driven in rotation as the first gear teeth rotate during dose delivery. The rotation sensor is responsive to the rotation of the second gear teeth to detect the rotation of the dose setting member.

Abstract: Drug delivery system comprising expelling means for expelling an amount of drug from a reservoir, the expelling means comprising dose setting means (11, 21, 122) allowing a user to set a dose to be expelled, and actuation means (123) for releasing the drug expelling means to expel the set dose. The dose setting means comprises a drive sleeve (22) adapted to be rotated to set a dose, and a rotatable driven member (21) arranged for being rotationally driven by the drive sleeve (22) in a slaved rotational movement by means of a torque transfer coupling between the drive sleeve (22) and the rotatable driven member (21). The system further comprises an electronically controlled capturing system for capturing data representing a property related to the amount of drug expelled from the reservoir by the expelling means, and switch means configured to initiate an action within the electronically con-trolled capturing system upon occurrence of the slaved rotational movement.

Abstract: An assembly for a medication delivery device includes a body, a piston rod, rotatable with respect to the body, for setting a dose of a medication, and axially movable in a distal direction for delivering the set dose, wherein, in cross-section, the piston rod includes a plurality of ratchet teeth to enable rotation of the piston rod during setting of a dose, and a stop member secured against axial and rotational movement, wherein the stop member mechanically cooperates with the piston rod, wherein, when setting the dose, the piston rod becomes aligned with the stop member, and wherein, when delivering the set dose, the piston rod is moved in the distal direction towards the stop member such that the piston rod and the stop member abut at the end of the dose delivery operation and further distal movement of the piston rod is prevented after dose delivery.

Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can be controlled to provide the liquid drug to the patient in a single dose or over multiple doses.

Abstract: A method of verifying that a first unit and a second unit being mounted to each other are correctly paired, the first unit comprising a first visual identifier and the second unit comprising a second visual identifier, the method comprising the steps of (i) capturing an image of the first and second unit mounted to each, the image comprising both the first and the second visual identifier, and (ii) processing the captured image to (a) identify the first and the second visual identifier, and (b) determine whether the captured identifiers represent a predefined combination of visual identifiers to thereby verify the pairing.

Abstract: An injection pen to deliver a predefined dose of substance according to a prescribed schedule is disclosed. The injection pen includes a first portion having a medicinal chamber and a removable cover. The medicinal chamber is coupled to a piston on one end and attachable to an injection needle on an opposite end. The removable cover includes a solution dispenser. The injection pen includes a second portion couplable to the first portion. The second portion includes an actuator coupled to the piston for actuating the piston in an injection. The actuator may be controlled by an electronic circuit board embedded within the injection pen to regulate the delivery of a substance in the medicinal chamber based on a prescribed dose and injection schedule.

Abstract: An injection device comprises a housing having a longitudinal axis, an axially-depressible dose button (430), a dose indicator (418), a dose setting mechanism operatively coupled to said dose indicator and capable of setting a dose to be ejected from the injection device and spring capable of storing energy necessary for ejecting the dose from the injection device. The spring (420) is coupled to the dose setting mechanism such that a charging force can be transferred from the dose setting mechanism to the spring to increase the energy stored by the spring.

Abstract: A medical device such as an infusion system detects that an accessory has been coupled to the device. The medical device initially operates in a first mode of operation. The medical device, in response to the detecting, associates the accessory with a different mode of operation for the medical device that requires changes to at least one of the operating parameters for the infusion system or elements within a graphical user interface. The medical device then automatically changes the mode of operation from the first mode of operation to the associated different mode of operation to reflect the coupling of the accessory to the infusion system. Related apparatus, systems, techniques and articles are also described.

Abstract: A sensor assembly comprising a first rotary sensor part having a plurality of individual electrically conducting code segments arranged in a circumferential pattern, and a plurality of electrically conducting reference segments between the code segments, and a second rotary sensor part arranged rotationally relative to the first part a plurality of contact structures, each contact structure being arranged to be in contact with either a code segment or a reference segment depending on the rotational position between the first and second rotary sensor part. The contact structures are configured to engage and connect to different sensor segments as the first and second rotary sensor part rotate relative to each, the created connections being indicative of a rotational position between the first and second rotary sensor part. For a given rotational position, at least one contact structure engages a code segment and at least one contact structure engages a reference segment.

Abstract: A communication device arranged for transmitting information from a medicament delivery device is presented. The communication device includes at least one rotation detection arrangement, the at least one rotation detection arrangement being configured to detect a rotation of at least one physical part of the medicament delivery device. The communication device also includes at least one determination unit configured to determine information related to a medicament delivery performed by the medicament delivery device. The communication device further includes at least one activation unit configured to activate the at least one determination unit based on the detected rotation. Also, the communication device includes at least one transmission unit configured to provide a wireless transmission of the information to an external receiving device.

Abstract: The present invention relates to a drive mechanism of a drug delivery device for setting and dispensing of a dose of a medicament, the mechanism comprising: a housing (20), a piston rod (120) to operably engage with a piston (14) of a cartridge (12) to displace the piston (14) in a distal direction (1), a rotatable member (80) arranged on an axially extending axis of rotation (4) in the housing (20), said rotatable member (80) being rotatable in a dose incrementing direction (5) against the action of a spring element (78) and being operably engageable with the piston rod (120) during dose dispensing, a clutch member (150) comprising at least one radially displaceable clutch element (153) to engage with a rim (82) of the rotatable member (80) with variably adjustable strength.

Abstract: A drug delivery device comprises a housing and a dose sleeve located within the housing, the dose sleeve being configured to move helically within the housing as a medicament dose is dialled into or delivered from the drug delivery device. A dose setting arrangement is coupled to the dose sleeve and is configured to cause helical movement of the dose sleeve as a medicament dose is dialled into the drug delivery device through rotation of a dose dial forming part of the dose setting component. A dose delivery arrangement comprising a dose button is coupled to the dose sleeve and is configured to cause delivery of medicament with helical movement of the dose sleeve and without rotation of the dose dial when the dose button is actuated. A first sensor arrangement is configured for detecting a rotation of the dose dial relative to the housing. A second sensor arrangement is configured for detecting movement of the dose sleeve relative to the housing.

Abstract: Disclosed is a milk suction and collection device integrally manufactured and formed by silicone. The milk suction and collection device includes a main body which is hollow inside to define a milk storage chamber and is further provided with a milk pouring port operative to be selectively blocked. A breast protecting film is provided on a side in a thickness direction of the main body and is configured to be fitted with an outer periphery of a breast, and is further provided with a milk collecting port communicating with the milk storage chamber. The side of the main body of the milk suction and collection device provided with the breast protecting film is operative to be fitted with the breast because the milk suction and collection device is integrally manufactured and formed by silicone. When the milk pouring port is closed, a breast pumping function is achieved by squeezing the main body. When the milk pouring port is opened, a milk collecting function is achieved.

Abstract: A method of providing and/or injecting octreotide acetate to a subject in need thereof includes storing the octreotide acetate in a cartridge of a multi-use multi-dose injector provided with a variable dose setter and actuator. The injector includes a needle configured for subcutaneous administration of the octreotide acetate, the octreotide acetate having a concentration of 2,500 ?g/mL. The method further includes providing, on the injector, a plurality of indicia only at prescribed doses of 50 ?g, 100 ?g, 150 ?g and 200 ?g settable via the dose setter without indicia between said prescribed doses; and permitting setting of a dose of the octreotide acetate by rotation of the variable dose setter, wherein the injector is configured to provide at least one audible feedback during the rotation.

Abstract: A medical injection system comprising an injection module, a retract module, and a bi-directional dose setting module. The bi-directional dose setting module comprises a dose plate, and the injection module comprises a dose knob engaged with the dose plate. The medical injection system generates a first response when the dose knob is rotated in the first direction, and generates a second response when the dose knob is rotated in the second direction.

Abstract: A patch pump utilizes piezoelectricity to dispense medicament from a cartridge syringe to a patient. Pump can include a plurality of piezoelectric elements that when energized cause linear motion of a pushrod that interfaces with the syringe in the cartridge to advance the syringe and dispense the medicament. The high torque generated by the piezoelectric elements is directly converted into the same amount of torque on the lead screw, so no torque increasing gear reduction system is needed and the pushrod utilized to drive the syringe can be contained within and connected directly to the motor assembly. Such a piezoelectric-based system can therefore be made smaller and with fewer moving parts than an electromagnetic motor of the same capability such that the pump has a smaller size than has heretofore been possible with prior art electromagnetic-based syringe pumps and other pumps that utilize gear reduction systems.

Abstract: The present disclosure relates to a drug delivery device for dispensing of a liquid medicament, the device comprising: a housing to accommodate a cartridge filled with the medicament and having a piston slidably displaced inside the cartridge along an axial direction and sealing a proximal end of the cartridge, a drive mechanism having a piston rod extending along the axial direction and being at least displaceable from a proximal end position in distal direction to displace the piston in distal direction, at least one distal support facing in proximal direction to axially abut a distally facing support face of the cartridge, wherein an axial distance between the distal support and a distal end of the piston rod when in the proximal end position is smaller than an effective length of the cartridge, which effective length is determined as the axial distance between a proximal face of the piston and the distally facing support face.

Abstract: Dosing device for an administration device with a limiting mechanism, comprising a first limiting means with a first stop means, a second limiting means with a second stop means, wherein the second limiting means follows movements of the first limiting means during dosing movements with a defined transmission ratio, and wherein the first and the second stop means each describe a path curve by their movements in such a manner that the two path curves intersect in at least one point or come so close together that the stop means contact one another in a stop position, whereby a blocking of the movement of the limiting means relative to each other during dosing movements can be effected in that the respective path curves described by the first and second stop means are closed and can be run through preferably multiple times by the first stop means, by the second stop means or by both stop means until the stop means contact one another at the stop position.

Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a cassette, a door coupled to the housing, a drive mechanism, and a latching assembly. The cassette is removably disposed within the inner volume and is adapted to contain a drug to be administered to a user. The door at least partially encloses the inner volume of the housing and includes a first end defining a latching portion. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the drug out the cassette. The latching assembly is coupled to the drive mechanism and includes a first end and a second end. Upon actuating the drive mechanism, the drive mechanism causes the latching assembly to engage the latching portion of the door to secure the door to the housing.

Abstract: Dose detection systems for medication delivery devices are described. One is a module for removable attachment to a dose button of a medication delivery device. A device with a dose detection system is also disclosed. The module includes a processor and a plurality of magnetic sensors, such as, for example, five or six sensors, operably coupled to the processor and configured to detect the positon of a rotating bipolar magnetic ring within the delivery device. Medication identification system may also be provided.

Abstract: Dosing device for an administration device with a limiting mechanism, comprising a first limiting means with a first stop means, a second limiting means with a second stop means, wherein the second limiting means follows movements of the first limiting means during dosing movements with a defined transmission ratio, and wherein the first and the second stop means each describe a path curve by their movements in such a manner that the two path curves intersect in at least one point or come so close together that the stop means contact one another in a stop position, whereby a blocking of the movement of the limiting means relative to each other during dosing movements can be effected in that the respective path curves described by the first and second stop means are closed and can be run through preferably multiple times by the first stop means, by the second stop means or by both stop means until the stop means contact one another at the stop position.

Abstract: The invention relates to an apparatus (2, 3), comprising a mating unit (20-1, 20-2) for releasably attaching the apparatus (2) to a medical device (1) or for releasably receiving at least a part of the medical device (1). The apparatus (2, 3) further comprises one or more optical sensors (25, 26) and/or one or more acoustical sensors (27) for determining information related to a condition and/or use of the medical device (1). The invention further relates to a system comprising such an apparatus (2, 3) and such a medical device (1), to a method (500, 600, 700) and a computer program (61) for determining information related to a condition and/or use of such a medical device (1), and to a computer-readable medium (60) storing such a computer program (61).

Abstract: A sub-1 ?L pipette having a small diameter metal tube that is concentrically located within the tip mounting shaft/portion of the pipette and extends from the distal end thereof by some predetermined distance so as to seal against the interior of a pipette tip that is installed to the tip mounting portion. The use of a small diameter metal tube and sealing of the metal tube against the inner surface of the pipette tip near a distal opening of the pipette tip allows for a minimal ullage volume.

Abstract: A system for capture of dose delivery information is provided. The system includes a medication delivery device, a dose information capture device adapted to be attached to the medication delivery device, and a target element adapted to be attached to the medication delivery device. The target element comprises a magnet or ferrous element and the target element attaches to the medication delivery device on a dose delivery mechanism of the medication delivery device. The dose information capture device includes a magnetic position sensor adapted to detect a position of the target element. As an alternative to magnetic sensing, MEMS flow sensors, and the like may also be used. Exemplary systems preferably transmit dose information in real time to remote devices for further processing.

Abstract: An optical sensor for a delivery device having a piston that displaces a substance, such as a fluid, from a reservoir. The optical sensor has a light source and a detector array for imaging encoding features disposed along a plunger rod coupled to the piston. By virtue of the pattern of encoding features, an absolute position of the plunger rod relative to a fiducial position may be determined uniquely. Thus, the volume of fluid remaining in the reservoir, the rate of fluid delivery, and proper loading of the reservoir may be accurately ascertained. Additionally, the encoding may serve to uniquely identify a version of the reservoir which may be supplied in various versions corresponding, for example, to differing concentrations of a therapeutic agent to be dispensed.

Abstract: Sensing systems are disclosed for determining the relative rotational movements of members of a medication delivery device which are proportional to the amount of a dose set and delivered by the medication delivery device. The sensing system comprises a first sensor component secured to a first member and a second sensor component secured to a second member. During dose setting, the second member is coupled to a third member which rotates relative to the first member in proportion to the dose set. During dose delivery, the second member is coupled to a fourth member which rotates relative to the first member in proportion to the dose delivered. The sensing system separately detects the relative rotational positions of the first and second sensor components during dose setting and dose delivery, and provides outputs used to determine the amounts of the set and delivered doses. The sensing system outputs this information to a controller which determines the amount of the dose set and delivered.