Having Means For Metering Material Flow To Or From Body Patents (Class 604/207)
  • Patent number: 11439766
    Abstract: The present disclosure relates to a dose detection system for use with a medication delivery device in which a dose setting member rotates relative to an actuator during dose delivery. The dose detection system comprises a module including a rotation sensor attached to the actuator during dose delivery. A sensed element is attached to the dose setting member and includes first gear teeth. The rotation sensor comprises a driven gear including second gear teeth. The second gear teeth are operatively received by the first gear teeth and are driven in rotation as the first gear teeth rotate during dose delivery. The rotation sensor is responsive to the rotation of the second gear teeth to detect the rotation of the dose setting member.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: September 13, 2022
    Assignee: Eli Lilly and Company
    Inventors: Matthew Thomas Antonelli, William Churchill Taliaferro Burke, Roy Howard Byerly, Russell Wayne Perkins, Kenneth Alan Ritsher, Elias Raad Samia
  • Patent number: 11400229
    Abstract: Drug delivery system comprising expelling means for expelling an amount of drug from a reservoir, the expelling means comprising dose setting means (11, 21, 122) allowing a user to set a dose to be expelled, and actuation means (123) for releasing the drug expelling means to expel the set dose. The dose setting means comprises a drive sleeve (22) adapted to be rotated to set a dose, and a rotatable driven member (21) arranged for being rotationally driven by the drive sleeve (22) in a slaved rotational movement by means of a torque transfer coupling between the drive sleeve (22) and the rotatable driven member (21). The system further comprises an electronically controlled capturing system for capturing data representing a property related to the amount of drug expelled from the reservoir by the expelling means, and switch means configured to initiate an action within the electronically con-trolled capturing system upon occurrence of the slaved rotational movement.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: August 2, 2022
    Assignee: Novo Nordisk A/S
    Inventor: Peter Lundholm Jensen
  • Patent number: 11389594
    Abstract: An assembly for a medication delivery device includes a body, a piston rod, rotatable with respect to the body, for setting a dose of a medication, and axially movable in a distal direction for delivering the set dose, wherein, in cross-section, the piston rod includes a plurality of ratchet teeth to enable rotation of the piston rod during setting of a dose, and a stop member secured against axial and rotational movement, wherein the stop member mechanically cooperates with the piston rod, wherein, when setting the dose, the piston rod becomes aligned with the stop member, and wherein, when delivering the set dose, the piston rod is moved in the distal direction towards the stop member such that the piston rod and the stop member abut at the end of the dose delivery operation and further distal movement of the piston rod is prevented after dose delivery.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: July 19, 2022
    Assignee: NORTON HEALTHCARE LIMITED
    Inventors: Christopher James Smith, Dale Marc Comley, Lee Thomas Smith
  • Patent number: 11383038
    Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can be controlled to provide the liquid drug to the patient in a single dose or over multiple doses.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: July 12, 2022
    Assignee: INSULET CORPORATION
    Inventors: David Nazzaro, Ian McLaughlin, Maureen McCaffrey, Simon Kozin, Jackie Mac
  • Patent number: 11357921
    Abstract: A method of verifying that a first unit and a second unit being mounted to each other are correctly paired, the first unit comprising a first visual identifier and the second unit comprising a second visual identifier, the method comprising the steps of (i) capturing an image of the first and second unit mounted to each, the image comprising both the first and the second visual identifier, and (ii) processing the captured image to (a) identify the first and the second visual identifier, and (b) determine whether the captured identifiers represent a predefined combination of visual identifiers to thereby verify the pairing.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: June 14, 2022
    Assignee: Novo Nordisk A/S
    Inventor: Michael Bech Reisenhus
  • Patent number: 11338093
    Abstract: An injection device comprises a housing having a longitudinal axis, an axially-depressible dose button (430), a dose indicator (418), a dose setting mechanism operatively coupled to said dose indicator and capable of setting a dose to be ejected from the injection device and spring capable of storing energy necessary for ejecting the dose from the injection device. The spring (420) is coupled to the dose setting mechanism such that a charging force can be transferred from the dose setting mechanism to the spring to increase the energy stored by the spring.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: May 24, 2022
    Assignee: Norton Healthcare Limited
    Inventors: Karl James Hewson, Jeremy James Robert Kooyman, Xorge Castro Pelayo
  • Patent number: 11338092
    Abstract: An injection pen to deliver a predefined dose of substance according to a prescribed schedule is disclosed. The injection pen includes a first portion having a medicinal chamber and a removable cover. The medicinal chamber is coupled to a piston on one end and attachable to an injection needle on an opposite end. The removable cover includes a solution dispenser. The injection pen includes a second portion couplable to the first portion. The second portion includes an actuator coupled to the piston for actuating the piston in an injection. The actuator may be controlled by an electronic circuit board embedded within the injection pen to regulate the delivery of a substance in the medicinal chamber based on a prescribed dose and injection schedule.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: May 24, 2022
    Inventor: Rundeep Gadh
  • Patent number: 11324886
    Abstract: A medical device such as an infusion system detects that an accessory has been coupled to the device. The medical device initially operates in a first mode of operation. The medical device, in response to the detecting, associates the accessory with a different mode of operation for the medical device that requires changes to at least one of the operating parameters for the infusion system or elements within a graphical user interface. The medical device then automatically changes the mode of operation from the first mode of operation to the associated different mode of operation to reflect the coupling of the accessory to the infusion system. Related apparatus, systems, techniques and articles are also described.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: May 10, 2022
    Assignee: CareFusion 303, Inc.
    Inventors: Carlos M. Nunez, James Alwan
  • Patent number: 11311678
    Abstract: A sensor assembly comprising a first rotary sensor part having a plurality of individual electrically conducting code segments arranged in a circumferential pattern, and a plurality of electrically conducting reference segments between the code segments, and a second rotary sensor part arranged rotationally relative to the first part a plurality of contact structures, each contact structure being arranged to be in contact with either a code segment or a reference segment depending on the rotational position between the first and second rotary sensor part. The contact structures are configured to engage and connect to different sensor segments as the first and second rotary sensor part rotate relative to each, the created connections being indicative of a rotational position between the first and second rotary sensor part. For a given rotational position, at least one contact structure engages a code segment and at least one contact structure engages a reference segment.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: April 26, 2022
    Assignee: Novo Nordisk A/S
    Inventors: John Oestergaard Madsen, Steffen Mews, Jacob Sonnerup Moellebro, Lars Peter Klitmose
  • Patent number: 11298465
    Abstract: A communication device arranged for transmitting information from a medicament delivery device is presented. The communication device includes at least one rotation detection arrangement, the at least one rotation detection arrangement being configured to detect a rotation of at least one physical part of the medicament delivery device. The communication device also includes at least one determination unit configured to determine information related to a medicament delivery performed by the medicament delivery device. The communication device further includes at least one activation unit configured to activate the at least one determination unit based on the detected rotation. Also, the communication device includes at least one transmission unit configured to provide a wireless transmission of the information to an external receiving device.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: April 12, 2022
    Assignee: SHL MEDICAL AG
    Inventors: Daniel Carlsson, Daniel Säll
  • Patent number: 11291774
    Abstract: The present invention relates to a drive mechanism of a drug delivery device for setting and dispensing of a dose of a medicament, the mechanism comprising: a housing (20), a piston rod (120) to operably engage with a piston (14) of a cartridge (12) to displace the piston (14) in a distal direction (1), a rotatable member (80) arranged on an axially extending axis of rotation (4) in the housing (20), said rotatable member (80) being rotatable in a dose incrementing direction (5) against the action of a spring element (78) and being operably engageable with the piston rod (120) during dose dispensing, a clutch member (150) comprising at least one radially displaceable clutch element (153) to engage with a rim (82) of the rotatable member (80) with variably adjustable strength.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: April 5, 2022
    Assignee: Sanofi
    Inventors: Stefan Bayer, Daniel Berning, Philippe Blank, Wolfgang Pelzer, Björn Wilden
  • Patent number: 11285268
    Abstract: A drug delivery device comprises a housing and a dose sleeve located within the housing, the dose sleeve being configured to move helically within the housing as a medicament dose is dialled into or delivered from the drug delivery device. A dose setting arrangement is coupled to the dose sleeve and is configured to cause helical movement of the dose sleeve as a medicament dose is dialled into the drug delivery device through rotation of a dose dial forming part of the dose setting component. A dose delivery arrangement comprising a dose button is coupled to the dose sleeve and is configured to cause delivery of medicament with helical movement of the dose sleeve and without rotation of the dose dial when the dose button is actuated. A first sensor arrangement is configured for detecting a rotation of the dose dial relative to the housing. A second sensor arrangement is configured for detecting movement of the dose sleeve relative to the housing.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: March 29, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Christian Rehbein
  • Patent number: 11273240
    Abstract: Disclosed is a milk suction and collection device integrally manufactured and formed by silicone. The milk suction and collection device includes a main body which is hollow inside to define a milk storage chamber and is further provided with a milk pouring port operative to be selectively blocked. A breast protecting film is provided on a side in a thickness direction of the main body and is configured to be fitted with an outer periphery of a breast, and is further provided with a milk collecting port communicating with the milk storage chamber. The side of the main body of the milk suction and collection device provided with the breast protecting film is operative to be fitted with the breast because the milk suction and collection device is integrally manufactured and formed by silicone. When the milk pouring port is closed, a breast pumping function is achieved by squeezing the main body. When the milk pouring port is opened, a milk collecting function is achieved.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: March 15, 2022
    Inventor: Shu Ting Zhang
  • Patent number: 11246991
    Abstract: A method of providing and/or injecting octreotide acetate to a subject in need thereof includes storing the octreotide acetate in a cartridge of a multi-use multi-dose injector provided with a variable dose setter and actuator. The injector includes a needle configured for subcutaneous administration of the octreotide acetate, the octreotide acetate having a concentration of 2,500 ?g/mL. The method further includes providing, on the injector, a plurality of indicia only at prescribed doses of 50 ?g, 100 ?g, 150 ?g and 200 ?g settable via the dose setter without indicia between said prescribed doses; and permitting setting of a dose of the octreotide acetate by rotation of the variable dose setter, wherein the injector is configured to provide at least one audible feedback during the rotation.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: February 15, 2022
    Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Satyashodhan Babasaheb Patil, Sudeep Kumar Agrawal, Subhas Balaram Bhowmick, Prashant Kane
  • Patent number: 11235107
    Abstract: A medical injection system comprising an injection module, a retract module, and a bi-directional dose setting module. The bi-directional dose setting module comprises a dose plate, and the injection module comprises a dose knob engaged with the dose plate. The medical injection system generates a first response when the dose knob is rotated in the first direction, and generates a second response when the dose knob is rotated in the second direction.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: February 1, 2022
    Assignee: SOLTEAM INCORPORATION
    Inventors: Chun-Yun Chang, Yeong-Lii Lin, Ping-Lung Lee, Frederic Delort, Chung-Yu Chen
  • Patent number: 11147916
    Abstract: A patch pump utilizes piezoelectricity to dispense medicament from a cartridge syringe to a patient. Pump can include a plurality of piezoelectric elements that when energized cause linear motion of a pushrod that interfaces with the syringe in the cartridge to advance the syringe and dispense the medicament. The high torque generated by the piezoelectric elements is directly converted into the same amount of torque on the lead screw, so no torque increasing gear reduction system is needed and the pushrod utilized to drive the syringe can be contained within and connected directly to the motor assembly. Such a piezoelectric-based system can therefore be made smaller and with fewer moving parts than an electromagnetic motor of the same capability such that the pump has a smaller size than has heretofore been possible with prior art electromagnetic-based syringe pumps and other pumps that utilize gear reduction systems.
    Type: Grant
    Filed: May 3, 2019
    Date of Patent: October 19, 2021
    Assignee: Tandem Diabetes Care, Inc.
    Inventor: Michael Michaud
  • Patent number: 11135358
    Abstract: The present disclosure relates to a drug delivery device for dispensing of a liquid medicament, the device comprising: a housing to accommodate a cartridge filled with the medicament and having a piston slidably displaced inside the cartridge along an axial direction and sealing a proximal end of the cartridge, a drive mechanism having a piston rod extending along the axial direction and being at least displaceable from a proximal end position in distal direction to displace the piston in distal direction, at least one distal support facing in proximal direction to axially abut a distally facing support face of the cartridge, wherein an axial distance between the distal support and a distal end of the piston rod when in the proximal end position is smaller than an effective length of the cartridge, which effective length is determined as the axial distance between a proximal face of the piston and the distally facing support face.
    Type: Grant
    Filed: September 5, 2016
    Date of Patent: October 5, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Andreas Bode
  • Patent number: 11103646
    Abstract: Dosing device for an administration device with a limiting mechanism, comprising a first limiting means with a first stop means, a second limiting means with a second stop means, wherein the second limiting means follows movements of the first limiting means during dosing movements with a defined transmission ratio, and wherein the first and the second stop means each describe a path curve by their movements in such a manner that the two path curves intersect in at least one point or come so close together that the stop means contact one another in a stop position, whereby a blocking of the movement of the limiting means relative to each other during dosing movements can be effected in that the respective path curves described by the first and second stop means are closed and can be run through preferably multiple times by the first stop means, by the second stop means or by both stop means until the stop means contact one another at the stop position.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: August 31, 2021
    Assignee: Ypsomed AG
    Inventors: Jürg Hirschel, Ulrich Moser
  • Patent number: 11071831
    Abstract: Dose detection systems for medication delivery devices are described. One is a module for removable attachment to a dose button of a medication delivery device. A device with a dose detection system is also disclosed. The module includes a processor and a plurality of magnetic sensors, such as, for example, five or six sensors, operably coupled to the processor and configured to detect the positon of a rotating bipolar magnetic ring within the delivery device. Medication identification system may also be provided.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: July 27, 2021
    Assignee: Eli Lilly and Company
    Inventors: Benjamin David Bauer, Timothy Mark Blum, Roy Howard Byerly, Andrea Concu, Marco Cortinovis, Paolo Degan, Jared Alden Judson, Rossano Claudio Massari, Kimberly Ann Ringenberger, Giorgio Maria Sardo, Amin Sedighiamiri, Marco Vergani
  • Patent number: 11071826
    Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a cassette, a door coupled to the housing, a drive mechanism, and a latching assembly. The cassette is removably disposed within the inner volume and is adapted to contain a drug to be administered to a user. The door at least partially encloses the inner volume of the housing and includes a first end defining a latching portion. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the drug out the cassette. The latching assembly is coupled to the drive mechanism and includes a first end and a second end. Upon actuating the drive mechanism, the drive mechanism causes the latching assembly to engage the latching portion of the door to secure the door to the housing.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: July 27, 2021
    Assignee: AMGEN INC.
    Inventors: Andrew Coles, Chad Quistad, Emanuele Strada, Francesco Lauritano, Alessia Mazzicone, Antonio Antonini
  • Patent number: 11058822
    Abstract: Dosing device for an administration device with a limiting mechanism, comprising a first limiting means with a first stop means, a second limiting means with a second stop means, wherein the second limiting means follows movements of the first limiting means during dosing movements with a defined transmission ratio, and wherein the first and the second stop means each describe a path curve by their movements in such a manner that the two path curves intersect in at least one point or come so close together that the stop means contact one another in a stop position, whereby a blocking of the movement of the limiting means relative to each other during dosing movements can be effected in that the respective path curves described by the first and second stop means are closed and can be run through preferably multiple times by the first stop means, by the second stop means or by both stop means until the stop means contact one another at the stop position.
    Type: Grant
    Filed: May 5, 2020
    Date of Patent: July 13, 2021
    Assignee: Ypsomed AG
    Inventors: Jürg Hirschel, Ulrich Moser
  • Patent number: 11062799
    Abstract: The invention relates to an apparatus (2, 3), comprising a mating unit (20-1, 20-2) for releasably attaching the apparatus (2) to a medical device (1) or for releasably receiving at least a part of the medical device (1). The apparatus (2, 3) further comprises one or more optical sensors (25, 26) and/or one or more acoustical sensors (27) for determining information related to a condition and/or use of the medical device (1). The invention further relates to a system comprising such an apparatus (2, 3) and such a medical device (1), to a method (500, 600, 700) and a computer program (61) for determining information related to a condition and/or use of such a medical device (1), and to a computer-readable medium (60) storing such a computer program (61).
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: July 13, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Schabbach, Amit Kohli
  • Patent number: 11007517
    Abstract: A sub-1 ?L pipette having a small diameter metal tube that is concentrically located within the tip mounting shaft/portion of the pipette and extends from the distal end thereof by some predetermined distance so as to seal against the interior of a pipette tip that is installed to the tip mounting portion. The use of a small diameter metal tube and sealing of the metal tube against the inner surface of the pipette tip near a distal opening of the pipette tip allows for a minimal ullage volume.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: May 18, 2021
    Assignee: Mettler-Toledo Rainin, LLC
    Inventor: James S. Petrek
  • Patent number: 10971260
    Abstract: A system for capture of dose delivery information is provided. The system includes a medication delivery device, a dose information capture device adapted to be attached to the medication delivery device, and a target element adapted to be attached to the medication delivery device. The target element comprises a magnet or ferrous element and the target element attaches to the medication delivery device on a dose delivery mechanism of the medication delivery device. The dose information capture device includes a magnetic position sensor adapted to detect a position of the target element. As an alternative to magnetic sensing, MEMS flow sensors, and the like may also be used. Exemplary systems preferably transmit dose information in real time to remote devices for further processing.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: April 6, 2021
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Gary Searle, Francis L Ross, III
  • Patent number: 10905825
    Abstract: An optical sensor for a delivery device having a piston that displaces a substance, such as a fluid, from a reservoir. The optical sensor has a light source and a detector array for imaging encoding features disposed along a plunger rod coupled to the piston. By virtue of the pattern of encoding features, an absolute position of the plunger rod relative to a fiducial position may be determined uniquely. Thus, the volume of fluid remaining in the reservoir, the rate of fluid delivery, and proper loading of the reservoir may be accurately ascertained. Additionally, the encoding may serve to uniquely identify a version of the reservoir which may be supplied in various versions corresponding, for example, to differing concentrations of a therapeutic agent to be dispensed.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: February 2, 2021
    Assignee: DEKA PRODUCTS LIMITED PARTNERSHIP
    Inventors: Marc A. Mandro, Larry B. Gray
  • Patent number: 10857304
    Abstract: Sensing systems are disclosed for determining the relative rotational movements of members of a medication delivery device which are proportional to the amount of a dose set and delivered by the medication delivery device. The sensing system comprises a first sensor component secured to a first member and a second sensor component secured to a second member. During dose setting, the second member is coupled to a third member which rotates relative to the first member in proportion to the dose set. During dose delivery, the second member is coupled to a fourth member which rotates relative to the first member in proportion to the dose delivered. The sensing system separately detects the relative rotational positions of the first and second sensor components during dose setting and dose delivery, and provides outputs used to determine the amounts of the set and delivered doses. The sensing system outputs this information to a controller which determines the amount of the dose set and delivered.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: December 8, 2020
    Assignee: Eli Lilly and Company
    Inventor: Roy H. Byerly
  • Patent number: 10850039
    Abstract: A drive assembly for a drug delivery device includes a spring member, a piston rod and a piston rod nut being engaged with the piston rod. The piston rod nut is configured to rotate and axially move during dose setting. The spring member is compressed when the piston rod nut is moved during the dose setting. The piston rod nut is rotationally fixed during dose dispensing.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: December 1, 2020
    Assignee: Sanofi
    Inventor: Simon Lewis Bilton
  • Patent number: 10799641
    Abstract: A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a housing having an opening, a dose selector operable to set a dose by rotation relative to the housing, a release member controlling movement of a piston in a dispensing direction, and a display comprising a units number wheel and a tens number wheel which are coupled to each other such that a continuous rotation of the units number wheel is translated into an intermittent rotary motion of the tens number wheel. The release member rotates, during dose dispensing, an angle corresponding to the dose set by the dose selector, thereby allowing a piston to move in a dispensing direction.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: October 13, 2020
    Assignee: Sanofi
    Inventors: Joseph Butler, Anthony Paul Morris, William Geoffrey Arthur Marsh, Matthew Meredith Jones
  • Patent number: 10799646
    Abstract: An injection device for delivering an injection comprises a housing having a longitudinal axis, a proximal end and a distal end, the housing being arranged such that the injection is delivered from its distal end; and a release mechanism comprising an impediment, the release mechanism being moveable between a first position, in which the impediment is in an impeding position so as to impede the delivery of the injection, and a second position, in which the impediment is in a non-impeding position so as to not impede the delivery of the injection, wherein the force required to move the release mechanism from the first position to the second position varies with the distance moved by the release mechanism, the variation in the force required with distance being represented by a force profile, which is non-linear.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: October 13, 2020
    Assignee: Cilag GmbH International
    Inventors: Ahmad Bitar, Douglas Ivan Jennings
  • Patent number: 10792435
    Abstract: An injection system, including an injector having a dispensing mechanism configured to dispense a medicament, and a ready-to-use indicator. The ready-to-use indicator includes a controller configured to interact with the ready-to-use indicator and an audio and/or visual indicator, a temperature sensor, and a temperature analog having similar thermodynamic properties of the medicament. The temperature sensor is configured to detect a temperature of the temperature analog which represents the dynamic temperature of medicament as the medicament is heated or cooled. The temperature sensor is configured to communicate the detected temperature to the controller and to alert the controller when a preset temperature is reached. The ready-to-use indicator is configured to alert a user when the preset temperature is reached, signifying the medicament is thermally ready to be delivered by the dispensing mechanism. The audio and/or visual indicator is configured to display indicate one or more notifications to the user.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: October 6, 2020
    Assignee: West Pharmaceutical Services, Inc.
    Inventors: Tommy Gene Davis, Brian Klueppel, Paul Benson, Anthony G. Esposito, Jason Choi
  • Patent number: 10792434
    Abstract: A medicament delivery device includes a body having a proximal end and a distal end, in turn comprising a distal housing part, and a medicament container holder, adapted to receive a medicament container; a dose setting drum for setting a dose when rotated in a first direction and for delivering a dose when rotated in a second direction, and a drive drum sleeve selectively operably connectable to a piston plunger for delivering a dose.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: October 6, 2020
    Assignee: SHL MEDICAL AG
    Inventor: Anders Wieselblad
  • Patent number: 10773025
    Abstract: An optical decoding system including an optical sensor integral with or attachable to a housing of a drug delivery device and configured to be directed at first and second rotatable components of a dose setting and dispensing mechanism of the drug delivery device and a processor configured to: (i) cause the optical sensor to capture images of the first and second rotatable components at least at the beginning and end of a medicament dose dispensing process; (ii) determine a rotational position of both the first and second rotatable components in each of the captured images; and (iii) determine from the rotational positions of the first and second rotatable components an amount of medicament delivered by the dose setting and dispensing mechanism of the drug delivery device.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: September 15, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Markus Ploch
  • Patent number: 10773032
    Abstract: A smart monitoring device for automatically monitoring the injection of medicines such as insulin which can be retrofitted to a conventional insulin pen in which the device has an optical motion sensor for detecting actuation of the injection pen together with an optional accelerometer sensor, medicament temperature and mounting sensors, the monitoring device being communicable with external smart devices such as smartphones.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: September 15, 2020
    Assignee: SHL MEDICAL AG
    Inventors: William Robert Cirillo, John Pascal Hughes
  • Patent number: 10758676
    Abstract: The present invention relates to a drug delivery device for setting and dispensing of a dose of a medicament is presented comprising a housing to accommodate a cartridge filled with the medicament, an electrically operated drive mechanism to be operably engaged with the cartridge to expel a predefined dose of the medicament from the cartridge, and at least one dose element displaceably arranged relative to the housing to set and/or to dispense the dose of the medicament, wherein the dose element and the drive mechanism are mechanically decoupled from each other.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: September 1, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Alex John Baker, James Andrew Holt, Timothy Lewis Sharpe
  • Patent number: 10751477
    Abstract: A determination device for determining a value representing a dose of a dose metering device includes an eddy-current-based rotational angle sensor. The rotational angle sensor can be coupled to a rotatable dosing knob of the dose metering device and can image a rotational angle of the dosing knob representing the dose in a rotational angle signal. The determination device further includes an analysis device that can establish the value of the dose using the rotational angle signal.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: August 25, 2020
    Assignee: Robert Bosch GmbH
    Inventors: Fabian Utermoehlen, Andreas Merz, Stefan Leidich
  • Patent number: 10702657
    Abstract: The present invention relates to an information provider assembly to be used with a medicament delivery device for providing status information of the medicament delivery device, which medicament delivery device is provided with a medicament dose setting mechanism, the information provider assembly comprising a housing designed to be releasibly connectable to said medicament delivery device, the information provider assembly further comprising a measuring unit capable of measuring the position of a measuring surface on said medicament delivery device, which measuring surface is moved as the medicament dose setting mechanism is operated.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: July 7, 2020
    Assignee: SHL MEDICAL AG
    Inventors: Daniel Säll, Rasmus Renstad, Nikolaj Hautaviita
  • Patent number: 10702658
    Abstract: A sliding cover for a liquid delivery device, such as a cap (100) for a pen injector (200), incorporates a set of sensors including a first optical sensor (110) with an output which changes during uncapping or capping motions on passing of a plunger (220) of the pen injector. This output is used together with at least one additional sensor output to determine the position of the plunger along a cylinder (210) of the liquid delivery device. By monitoring changes in the plunger position, the quantity of dosages delivered by the liquid delivery device can be determined, displayed, stored and/or transmitted to an external device for further data processing or storage.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: July 7, 2020
    Assignee: PATIENTS PENDING LTD.
    Inventor: Avraham Shekalim
  • Patent number: 10695504
    Abstract: A drug delivery system comprises means to create a log of expelled dose amounts of drug. Stored dose amounts determined within a given time period are combined to a single combined dose amount. The given time period is initiated by a detected expelling event taking place (i) a given amount of time after a previous detected expelling event, or (ii) after a given detected action. By this arrangement it is possible to create a log corresponding to what a user considers to be a single dose, i.e. combining “split doses” to create a single log entry for a per se split dose.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: June 30, 2020
    Assignee: Novo Nordisk A/S
    Inventors: Preben Mikael Nielsen, Nikolaj Frogner Krusell, Jens Christian Andersen, Nikolaj Eusebius Jakobsen
  • Patent number: 10695499
    Abstract: The present invention provides a method of manufacturing a prefilled drug delivery device comprising the steps of arranging a piston rod member (20, 22, 120, 122) and a piston rod guide (40, 140) in a housing (10, 110) such that the piston rod member extends through a guide structure (13, 113) fixed in the housing and is surrounded by and operatively coupled with the piston rod guide, whereby rotation of the piston rod guide in a first direction relative to the housing causes distal movement of the piston rod member relative to the guide structure, and vice versa, and rotation of the piston rod guide in a second direction relative to the housing causes proximal movement of the piston rod member relative to the guide structure, and vice versa, and the piston rod guide is in a first state being capable of bi-directional rotation with respect to the housing, bringing a displaceable wall (62, 162) of a variable volume drug reservoir (60, 160) into abutment with a distal end portion of the piston rod member, movin
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: June 30, 2020
    Assignee: Novo Nordisk A/S
    Inventors: Carsten Schau Andersen, Simon Roervig, Steffen Hansen
  • Patent number: 10688246
    Abstract: The present disclosure relates to an injection device for setting and dispensing of a dose of a medicament, the device including an elongated housing to accommodate a cartridge filled with the medicament and sealed with a piston, a piston rod extending along a first axis and being threadedly or slidingly engaged with the housing to apply a distally directed thrust to the piston of the cartridge, a drive member rotationally or threadedly engaged with the piston rod and having a wheel section or geared section, and a drive sleeve extending along a second axis at a radial distance from the first axis and having a geared section to mesh with the wheel section or geared section of the drive member, wherein a first radial distance between first and second axes at a distal end of the drive sleeve differs from a second radial distance between first and second axes at a proximal end of the drive sleeve.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: June 23, 2020
    Assignee: Sanofi
    Inventors: Anthony Paul Morris, Matthew Meredith Jones, Oliver Benjamin Brown
  • Patent number: 10684156
    Abstract: Embodiments described herein generally relate to devices, systems and methods for measuring the dose remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a plurality of light sources which are disposed and configured to emit electromagnetic radiation toward the container. A plurality of sensors are located in the apparatus that are optically coupleable to the plurality of light sources and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light sources. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: June 16, 2020
    Assignee: Common Sensing Inc.
    Inventors: Richard Whalley, James White
  • Patent number: 10668219
    Abstract: A finger grip arranged to be connected to a syringe barrel having a plunger and a plunger rod for driving said plunger. The finger grip includes a body having a lower side with finger supporting surfaces for supporting fingers of a user during handling and an engagement member being moveable between an inactive position where the engagement member is arranged not to engage with the plunger rod of the syringe barrel and an active position where the engagement member is arranged to engage with a grooved surface on the plunger rod of the syringe such that feedback is given to a user as the plunger is moved relative to the finger grip. An activation member for moving the engagement member from said inactive position to said active position is built-in into the finger grip.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: June 2, 2020
    Assignee: NESTLÉ SKIN HEALTH S.A.
    Inventors: Jonas Tornsten, Max Blomqvist, Pekka Niskala
  • Patent number: 10668222
    Abstract: An assembly for a drug delivery device is provided comprising a screw member comprising a thread, the thread including at least two consecutive portions, the portions having different leads. The device further includes a nut member. The assembly is configured such that, in a first portion of the thread, the nut member includes a first position with respect to an axis transversal to the rotational axis and in a second portion of the thread, the nut member includes a second position with respect to the axis transversal to the rotational axis. The nut member is configured to perform a tilting movement from the first position into the second position when the nut member passes from the first portion to the second portion. Furthermore, a drug delivery device comprising the assembly is described.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: June 2, 2020
    Assignee: Sanofi
    Inventor: Paul Roger Griffin
  • Patent number: 10661020
    Abstract: A mechanical device for assisting medication injection is provided herein comprising a connector having a distal end and a proximal end; a piston rod locked in said connector before medication injection; a spring configured to bias said piston rod distally; a releasable restraining means configured to releasably restrain said piston rod in a locked state against said biasing of said spring, wherein, upon release of said releasable restraining means, said piston rod moves distally under force of said spring; an activation means configured to release said releasable restraining means; and a mounting means for mounting a syringe at said distal end of said connector.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: May 26, 2020
    Inventor: Min Wei
  • Patent number: 10603435
    Abstract: The disclosure is directed to a drive mechanism for use in a drug delivery device having a cartridge, the mechanism comprising a base element, a toothed piston rod movable from a first retracted position corresponding to a full cartridge to a second extended position corresponding to an empty cartridge, wherein the piston rod is guided within and movable relative to the base portion, and a drive gear having a pinion, which is rotatably held in the base element and in meshed engagement with the toothed piston rod, wherein the toothed piston rod comprises multiple rigid rod pieces which are connected by hinges, and a drive spring, which is fixed to the base element with one end and fixed to the drive gear with another end and which exerts a force or torque to the drive gear for rotating the drive gear relative to the base element, which rotation results in a movement of the toothed piston rod.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: March 31, 2020
    Assignee: Sanofi
    Inventors: William Geoffrey Arthur Marsh, Matthew Meredith Jones, Joseph Butler, Anthony Paul Morris
  • Patent number: 10576210
    Abstract: The present disclosure relates to a drive mechanism for an injection device for setting and dispensing of a dose of a medicament, the drive mechanism including a tubular shaped housing component extending in an axial direction (z) and comprising an inner thread, a tubular shaped display member having an outer thread engaged with the inner thread, and a dose member axially displaceable between a dose setting position (S) and a dose dispensing position relative to the display member, wherein the display member includes at least one blocking member on its outer circumference to axially engage with a blocking structure on an inside facing sidewall portion of the housing component to block an axial displacement of the dose member from the dose setting position (S) towards the dose dispensing position.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: March 3, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: David Aubrey Plumptre, Robert Veasey, John David Cross
  • Patent number: 10569025
    Abstract: An injection device for dosing and for releasing a defined dose of a liquid product includes: a threaded rod with a thread that includes teeth; a rotating sleeve with an engaging element that can engage with the teeth of the threaded rod; a guide sleeve having an engaging element that can engage with the teeth of the threaded rod; and a dosing sleeve arranged in an axially moveable manner in relation to the rotating sleeve and the guide sleeve, the dosing sleeve in a threaded engagement with the rotating sleeve.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: February 25, 2020
    Assignee: TecPharma Licensing AG
    Inventors: Markus Tschirren, Juerg Hirschel
  • Patent number: 10543316
    Abstract: An injector for injecting a medicament in a patient. The injector includes a container comprising a fluid chamber containing a first volume of a medicament, and an injection conduit associated with the fluid chamber for defining a fluid pathway therefrom to inject the medicament from the fluid chamber through the injection conduit to an injection location. The injector also includes a firing mechanism associated with the fluid chamber for expelling the medicament from the fluid chamber through the injection conduit, and a volume-control mechanism operable to control a fraction of the first volume of medicament that is injected when the firing mechanism is actuated to inject the medicament.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: January 28, 2020
    Assignee: Antares Pharma, Inc.
    Inventors: Paul R. Lesch, Matthew H. Rust, Thomas E. Kramer
  • Patent number: 10532160
    Abstract: An optical decoding system comprising: a first optical sensor configured to be directed at a first rotatable component of a drug delivery device; a second optical sensor configured to be directed at a second rotatable component of a drug delivery device; and a processor configured to: receive signals from the first optical sensor, wherein the signals from the first optical sensor represent encoded dosage values present on the first rotatable component; receive signals from the second optical sensor, wherein the signals from the second optical sensor represent whether the second rotatable component is rotating or not; and to determine from the received signals whether the drug delivery device is in a drug dose dialling mode or a drug dose delivery mode.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: January 14, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Paul Richard Draper
  • Patent number: 10493211
    Abstract: An injection device includes a housing; a receptacle for injection fluid; a dosing piston to press out the injection fluid; a feed part connected to the dosing piston via a first threaded connection; a slide having a thread of a second threaded connection; and, a setting part having a thread of a third threaded connection and configured to set an amount of injection fluid to be dispensed. The setting part moves in the distal direction by virtue of the third threaded connection when the amount of injection fluid to be dispensed is being set. The setting part can move in the proximal direction when the injection fluid is pressed out. A latching unit defines a latching position of the setting part and acts between the setting part and housing. Each latching position has an unequivocal rotational position of the setting part in relation to the housing assigned thereto.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: December 3, 2019
    Assignee: Haselmeier AG
    Inventor: Joachim Keitel