Including Means For Controlling Piston Stroke Length Patents (Class 604/208)
  • Patent number: 11426525
    Abstract: An assembly for a drug delivery device comprises a housing, a dose member which is displaceable in a proximal direction with respect to the housing for setting of a dose of a drug, a clutch member which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member configured to define a clutch stop position. The clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose.
    Type: Grant
    Filed: August 5, 2021
    Date of Patent: August 30, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Strehl, Udo Leuschner, Norbert Besenhardt
  • Patent number: 11400227
    Abstract: The present invention provides a drug injection device (1) for delivering multiple doses of drug, comprising: a housing (2) extending along a main axis, a dose expelling mechanism comprising a piston rod (60) configured to move relative to the housing (2) from a first position to a second position to cause ejection of a dose of drug, the piston rod (60) extending between a proximal piston rod end and a distal piston rod end and comprising a dosing track (63), the piston rod (60) further being movable relative to the housing (2) from an initial pre-use position to a final end stop position to cause accumulated ejection of a predefined total dose, a dosing track follower (17) fixed with respect to the housing (2) and adapted to travel the dosing track (63) during dose ejection, a dose setting mechanism operable to set the dose to be ejected by the dose expelling mechanism, electronic means (82, 90, 91, 92, 95) for registering a dose setting operation and for registering a dose size of an ejected dose, and a dis
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: August 2, 2022
    Assignee: Novo Nordisk A/S
    Inventor: Nikolaj Eusebius Jakobsen
  • Patent number: 11364336
    Abstract: A device for delivering a fluid includes a housing defining an interior space and having a bottom surface configured for contacting a patient. The bottom surface defines a needle opening. The device also includes a reservoir disposed within the interior space of the housing for containing a fluid therein, a needle carrier disposed within the housing, and an injection needle supported by the needle carrier and defining a lumen. The lumen of the injection needle is configured to be placed in fluid communication with the reservoir. The injection needle is transitionable from an initial position in which the injection needle is disposed within the housing, to a use position in which the injection needle extends through the needle opening, and a substantially shielded position in which the injection needle is disposed within the housing and the lumen of the needle is blocked by a portion of the housing.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: June 21, 2022
    Assignee: Becton, Dickinson and Company
    Inventor: Richard Cronenberg
  • Patent number: 11338090
    Abstract: A system is disclosed for inserting a pharmaceutical cartridge into a delivery device. Optionally the cartridge is inserted in an arbitrary orientation. Optionally, the system reorients the cartridge to a locked orientation. For example, a driver applies a torque to the cartridge to cause the reorienting. For example, said torque rotates the cartridge around an axis thereof until the cartridge reaches the locked orientation. Optionally, when the cartridge reaches the locked orientation an interference element on the cartridge interlocks with a complementary interference element on the delivery device to lock the cartridge in the locked orientation. Optionally when the cartridge is locked in the second orientation, the torque causes discharge the pharmaceutical.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: May 24, 2022
    Assignee: West Pharma. Services IL, Ltd.
    Inventors: Lior Barchen, Yossi Bar-El
  • Patent number: 11298464
    Abstract: An assembly for a drug delivery device includes a housing, a rotation member, a drive member and at least one correction member. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in a first rotational direction. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member. For switching from the delivery mode into the correction mode, the correction member is moveable with respect to the housing, wherein the assembly is configured such that movement of the correction member with respect to the housing is converted into a relative movement between the drive member and the rotation member for decoupling the drive member and the rotation member.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: April 12, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Philippe Nzike, Steffen Raab, Uwe Dasbach, Uwe Boeser, Ulrich Bruggemann
  • Patent number: 11266790
    Abstract: Apparatus and methods for providing controlled pressure-flow pulses which purge a catheter system with turbulent flow flushing. Accomplishment of such controlled pressure-flow pulses is provided by a variety of inventive devices including a special plunger rod for a conventional syringe, other interactive parts for conventional syringes, an in-line catheter attachable device which automatically generates the controlled pressure-flow pulses and also single pulse, digitally operated devices.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: March 8, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Michael W. Howlett, James V. Mercer, Amelio Paolucci
  • Patent number: 11241544
    Abstract: The invention relates to a medical injection device having polymeric housing. The housing comprises a moulded outer housing element and a moulded ring-shaped unitary element. The ring-shaped unitary element carries a pointer and a thread segment in predetermined and correlated positions. The pointer points to indicia on a scale drum and the thread segments guides the scale drum. The outer housing element is moulded over the unitary element to form one single component.
    Type: Grant
    Filed: November 27, 2014
    Date of Patent: February 8, 2022
    Assignee: Novo Nordisk A/S
    Inventors: Ken Hansen, Imran Ghulam, Jesper Bach Noergaard, Claus Urup Gjoedesen, Asger Meng Larsen
  • Patent number: 11141206
    Abstract: The invention relates to the field of bioresorbable or non-bioresorbable bone substitutes to be implanted in humans in order to reconstitute the bone supply by replacing lost bone substance. More particularly, the invention concerns a device that is simple to manufacture and use and comprises a syringe provided with a single-use dose of a polymer which is fluid at the injection temperature while being solid and durable at body temperature.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: October 12, 2021
    Assignee: TEKNIMED
    Inventors: Julien Iehl, Gautier Halbin, Cyril Sender, Nouredine Sahraoui
  • Patent number: 11090436
    Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing and at least two separate component parts, wherein for example at least one of these component parts performs a movement relative to the housing during dose setting and for example at least one of these component parts performs a movement relative to the housing during dose dispensing, and wherein the relative movement of the at least two separate component parts with respect to each other during dose setting differs from the relative movement of the at least two separate component parts with respect to each other during dose dispensing.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: August 17, 2021
    Assignee: Sanofi
    Inventors: Richard James Vincent Avery, Matthew Meredith Jones, William Marsh, Anthony Paul Morris, David Aubrey Plumptre, Samuel Keir Steel, Robert Frederick Veasey
  • Patent number: 11090441
    Abstract: A syringe includes a barrel having an internal surface defining an internal bore therein; a plunger having a distal end disposed within the internal bore of the barrel, and a proximal end disposed outside the internal bore of the barrel; and a dose divider configured to bear on the barrel in response to translation of the plunger relative to the barrel along the longitudinal direction. The dose divider includes a base including a flange that extends at least partly in a radial direction; and at least one column extending away from the base along the longitudinal direction. The at least one column includes a proximal end and a distal end opposite the proximal end, the proximal end of the at least one column being coupled to the base. The at least one column includes a sacrificial portion coupled to a frangible link.
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: August 17, 2021
    Assignee: TELEFLEX MEDICAL INCORPORATED
    Inventors: Huy Tran, Perry Croll
  • Patent number: 11065393
    Abstract: A device for administering a fluid product, the device including a first housing part provided with a receiver for the product, a second housing part detachably connectable to the first housing part, a piston rod held such that it can be displaced for the exertion of an emptying movement, an actuatable or releasable drive element for the piston rod, a coupling element including a coupling input element that couples the drive element to the piston rod in a coupling engagement, transmits a driving force of the drive element to the piston rod, and triggers the emptying movement, and a decoupling element displaceably connected to the second housing part and coupled to the first housing part such that it is displaced, by a movement of the housing parts in relation to each other when the housing parts are separated into a decoupling position wherein the piston rod is decoupled from the coupling input element.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: July 20, 2021
    Assignee: Ypsomed AG
    Inventors: Philippe Kohlbrenner, Daniel Kuenzli, Christoph Meier, Peter Stettler, Juergen Wittmann, Martin Wittwer
  • Patent number: 11065392
    Abstract: The disclosure relates to injectors that are configured to inject and deliver medicaments and other fluids from a syringe into a target site.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: July 20, 2021
    Assignee: Action Medical Technologies, LLC
    Inventors: Joseph B. Hoffer, Mark W. Pursel, Kevin C. O'Connor, Andrew D. Contreras, James P. McCans
  • Patent number: 11058811
    Abstract: A configurable fluid delivery system and methods for its use are disclosed. The system may include one or more control units, fluid delivery units, fluid actuator units, and disposable units. Data sources and sensors on each of the delivery units, actuator units, and disposable units may provide data to the control unit, thereby identifying the components along with the manner in which they may be configured. The control unit may notify a user regarding the status of any one or more of the delivery, actuator, and disposable units to indicate their appropriateness for delivering a fluid according to one or more selected procedures and protocols. Also disclosed are methods by which the configurable fluid delivery system may provide data to a user to assist the user in assembling and testing a particular configuration of the fluid delivery system for a specific use.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: July 13, 2021
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Arthur E. Uber, III, Mark Trocki
  • Patent number: 11058824
    Abstract: A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: July 13, 2021
    Assignee: Antares Pharma, Inc.
    Inventors: Janice L. Cox, Matthew H. Rust, Thomas E. Kramer, Peter A. Hoeft
  • Patent number: 11052200
    Abstract: A cap (120) for a drug delivery device (1) having a distal end (121) and a proximal end (122); the cap (120) having an opening at the proximal end and further comprising an outer cap element (130) and an inner cap element (131) being located inside the outer cap element (130), the inner cap element (131) comprising a deformable region (151) and a cap snap means (149); wherein the deformable region (151) of the inner cap element (131) is deformable into a gap (143) between the inner cap element (131) and the outer cap element (130).
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: July 6, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: David Aubrey Plumptre
  • Patent number: 11052194
    Abstract: An injection device for delivering equal doses of a fluid contained in a reservoir, the device having a housing, and an arming mechanism and a dose delivery mechanism arranged therein, the housing coupled to an enclosure for the reservoir. The arming mechanism includes an axially non-displaceable and rotatable setting sleeve. The setting sleeve is coupled with a spring strained by the rotation of the setting sleeve during arming of the device. The dose delivery mechanism includes a screw ring and a non-rotatable and axially displaceable piston rod within the setting sleeve. The piston rod cooperates with the screw ring so that during arming, the screw ring and the piston rod are immobilized, and during delivery of each dose the piston rod is displaced along the housing due to unwinding of the spring and rotation of the screw ring, the displacement of the piston rod causing the fluid to be discharged from the reservoir.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: July 6, 2021
    Assignee: COPERNICUS SP. Z O.O.
    Inventors: Adam Stefanski, Alberto Lozano Platonoff
  • Patent number: 11027068
    Abstract: The disclosure relates to a syringe support for supporting an axial position of a syringe relative to a housing of an autoinjector. The syringe support includes a supporting beam arranged on the syringe support and biased radially inwards. The supporting beam is adapted to axially bias the syringe in a distal direction within the housing. The disclosure further relates to an autoinjector.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: June 8, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Carsten Mosebach, Thomas Mark Kemp
  • Patent number: 11000649
    Abstract: An assembly for a drug delivery device is provided comprising a housing, and a lead screw having a longitudinal axis, a distal end and a proximal end, the lead screw being rotatably fixed during dose setting and dose delivery and axially movable in a distal direction relative to the housing, the lead screw further including a thread. The assembly further comprises a drive nut threadedly engaged with and screwable along the lead screw thread and a dial link connected with the drive nut and axially movable and rotatably fixed relative to the drive nut, where the dial link comprises a first portion of a feedback ratchet. The assembly is configured such that, during dose delivery, the assembly generates a feedback signal.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: May 11, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Blancke, Axel Teucher, Michael Jugl, Christiane Schneider
  • Patent number: 10967135
    Abstract: This disclosure concerns a method for removing gas and/or gas bubbles from a liquid medicament stored in a reservoir for an infusion pump device. The reservoir comprises a displacing member which is at least partly displaceable relative to the reservoir thereby enabling receiving mechanical oscillations in order to generate mechanical waves in the liquid medicament. The method comprises: providing the reservoir; and transmitting a mechanical oscillation to the displacing member of the reservoir thereby generating a mechanical wave in the liquid medicament for removing gas and/or gas bubbles from the liquid medicament.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: April 6, 2021
    Assignee: Roche Diabetes Care, Inc.
    Inventor: Frank Deck
  • Patent number: 10918793
    Abstract: A medical delivery device is disclosed that includes a rod element, a dosage member and a lock mechanism. A stem of the rod element extends into an interior of a chamber body of the dosage member and a delivery orifice of the dosage member is arranged adjacent to a proximal end of the stem of the rod element. In a dosing status, the rod element is movable relative to the delivery orifice of the dosage member, such that a dosage chamber is formed within the chamber body between the stem of the rod element and the delivery orifice, wherein the dosage chamber increases when the rod element moves away from the delivery orifice. The lock mechanism changes the medical delivery device from a lock status to the dosing status, wherein in the lock status the rod element is prevented from moving relative to the dosage member delivery orifice.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: February 16, 2021
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Maxime Gaillot, Roberta Leah, Declan Reilly, Mark Digby Teucher, Paul Graham Hayton, Jonathan Paul Ridley, James Robert Coop
  • Patent number: 10918794
    Abstract: A medical delivery device is disclosed having a rod element and a dosage member. The rod element has a stem and a first thread arrangement. The dosage member includes a delivery orifice, a chamber body and a second thread arrangement. The stem of the rod element extends within the chamber body and the delivery orifice is arranged adjacent to a proximal end of the stem. The dosage chamber is formed within the chamber body between the stem and the delivery orifice such that the dosage chamber increases when the rod element moves away from the delivery orifice. In a dosing status, the first thread arrangement of the rod element engages the second thread arrangement of the dosage member such that the rod element is moveable along its longitudinal axis relative to the delivery orifice of the dosage member.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: February 16, 2021
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Maxime Gaillot, Roberta Leah, Declan Reilly, Mark Digby Teucher, Paul Graham Hayton, Jonathan Paul Ridley, James Robert Coop
  • Patent number: 10918795
    Abstract: A medical delivery device is disclosed including a rod element, a dosage member and a lock mechanism. The rod element has a stem and the dosage member includes a delivery orifice and a chamber body. The stem of the rod element extends into the chamber body and the delivery orifice is arranged adjacent to a proximal end of the stem. In a dosing status, the rod element is movable along its longitudinal axis relative to the delivery orifice, wherein a dosage chamber is formed within the chamber body between the stem and the delivery orifice such that the dosage chamber increases when the rod element moves away from the delivery orifice. The lock mechanism is adapted to change the medical delivery device from a lock status to a dosing status, wherein, in the lock status moving the rod element along its longitudinal axis relative to the delivery orifice is prevented.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: February 16, 2021
    Assignee: HOFFMANN-LA ROCHE INC
    Inventors: Maxime Gaillot, Roberta Leah, Declan Reilly, Mark Digby Teucher, Paul Graham Hayton, Jonathan Paul Ridley, James Robert Coop
  • Patent number: 10912890
    Abstract: A medical delivery device is disclosed having a rod element with a stem and a first thread arrangement, a dial shell with a second thread arrangement, a delivery orifice, and a switching mechanism. In a dosing status, the rod element is movable relative to the delivery orifice by rotating the dial shell around the stem causing the first thread arrangement and the second thread arrangement to travel along each other, a dosage chamber is formed between the rod element and the delivery orifice when the rod element moves away from the delivery orifice, and the rod element is prevented from movement along a longitudinal axis when an axial force is applied. In a delivery status, the rod element is movable along the longitudinal axis relative to the delivery orifice when an axial force is applied and moving the rod element by rotating the dial shell around the stem is prevented.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: February 9, 2021
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Maxime Gaillot, Roberta Leah, Declan Reilly, Mark Digby Teucher, Paul Graham Hayton, Jonathan Paul Ridley, James Robert Coop
  • Patent number: 10835676
    Abstract: A push button safety injector includes a housing having a proximal end, a distal end spaced from the proximal end, and a longitudinal axis. An injection ram is positioned along the longitudinal axis and configured to actuate a fluid chamber. The injection ram is biased toward the distal end in an initial position. A sliding member is configured to retain the injection ram in the initial position. A safety member confines radial movement of the sliding member in the initial position and allows radial movement of the sliding member in an armed position. A button is moveable between an initial extended position and a depressed position. The button is engagable with the sliding member and configured to move the sliding member radially in the armed position. The sliding member releases the injection ram when the button is in the depressed position.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: November 17, 2020
    Assignee: Antares Pharma, Inc.
    Inventors: Kevin David Swanson, Julius Sund, Peter A. Hoeft, Patrick E. Madsen
  • Patent number: 10821235
    Abstract: A medication injection pen, comprising a housing, a dose set knob that rotates with respect to the housing during dose setting and dose correcting, and a driver selectively engaged with the dose set knob, the driver rotatably fixed with respect to the housing during dose setting and dose correcting, wherein the driver moves axially with the dose set knob during dose setting and dose correcting, and the driver rotates with the dose set knob during an injection.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: November 3, 2020
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Michael Quinn, Richard Cronenberg
  • Patent number: 10799643
    Abstract: A drive-control system for an injection device for delivering settable doses of a pharmaceutical substance contained in a cartridge (3), the system comprising a tubular housing body (2) having a longitudinal axis (A-A), a proximal end (2a) and a distal end (2b) connectable to the cartridge enclosure (3), the system further comprising a helical spring (7) contained in the housing body and a piston rod (6) moveable towards said distal end (2b) and blocked in translation towards the proximal end (2a).
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: October 13, 2020
    Assignee: COPERNICUS SP. Z O.O.
    Inventors: Alberto Lozano Platonoff, Mateusz Wilczek, Adam Stefanski
  • Patent number: 10780232
    Abstract: The present disclosure relates to a pen injecting device for delivering a liquid medicament comprising a pen body and a needle is received in a first end of the pen body. The pen injecting device further comprises an inner needle shield, removeably located over the needle to enclose the needle, and an outer needle shield, removeably located over the inner needle shield to enclose the inner needle shield. The pen injecting device also comprises a pen cap removeably attached to the first end of the pen body so as to enclose the outer needle shield. The pen cap comprises an arm depending from an inside surface of the cap and extending away from the first end of the pen body toward the inner and outer needle shields, the arm having a sharp end so that, as the cap is removed from the body, the sharp end of the arm grips the inner or outer needle shield to retain it in the cap and expose the needle.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: September 22, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Jugl, Stefan Blancke, Axel Teucher, Claudia Biedermann
  • Patent number: 10729855
    Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: August 4, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
  • Patent number: 10702661
    Abstract: Disclosed is an injection device (1280) for injecting a hypodermic syringe (1260) along an injection direction defining an injection axis. The injecting device comprises a housing (1281) for being positioned at the skin and a movable element (1282) movably arranged relative to the housing between a retracted position and an injection position. The movable element comprises a hypodermic syringe holder (1289) for holding a hypodermic syringe. Disclosed is further a protective cover (1200) for a needle, and methods for arranging a hypodermic syringe in an injection device.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: July 7, 2020
    Assignee: UNION MEDICO APS
    Inventor: Michael Perthu
  • Patent number: 10702659
    Abstract: The present invention is generally directed to an assembly for a drug delivery device comprising a first threaded member (50, 50?), a second threaded member (40, 60?) with a longitudinal axis and a thread (61), having at least two consecutive portions (62, 63, 64) with different leads. The first threaded member (50, 50?) and the second threaded member (40, 60?) are adapted and arranged to rotate with respect to one another about the longitudinal axis of the second threaded member (40, 60?) during dose setting operation of the assembly, the first threaded member (50, 50?) thereby being axially displaced along the second threaded member (40, 60?) from a start position to an end position with respect to the second threaded member (40, 60?) due to the mechanical cooperation of the first threaded member (50, 50?) with the thread (61).
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: July 7, 2020
    Assignee: Sanofi
    Inventors: Anthony Paul Morris, Paul Griffin
  • Patent number: 10688248
    Abstract: An injection device includes a housing, a resilient member adapted to provide a force necessary for ejecting a dose from the injection device, and a dose setting member operatively connected to a dose indicator which is positioned within the housing. The dose setting member and the dose indicator cooperate to set the dose to be ejected from the injection device. The dose indicator, during dose setting, is adapted to undergo a rotational movement within the housing and relative to the housing. Further, a gauge element is provided which is rotationally constrained to the housing and axially displaceable relative to the housing. The gauge element and the dose indicator form a limiter mechanism defining a maximum settable dose and/or a minimum settable dose.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: June 23, 2020
    Assignee: Sanofi
    Inventors: Matthew Jones, Simon Lewis Bilton
  • Patent number: 10632262
    Abstract: This disclosure relates to a drive mechanism for a drug delivery device and to a respective drug delivery device. The drive mechanism includes an elongated housing extending in an axial direction, an actuation member rotatably supported on the housing for setting of the dose. The drive mechanism further includes a last dose sleeve directly rotatably engaged with the actuation member and having at least one stop and a last dose member threadedly engaged with the last dose sleeve. The last dose member is further rotatably fixed to the housing and is operable to engage with the at least one stop to limit a rotation of the last dose sleeve.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: April 28, 2020
    Assignee: Sanofi
    Inventors: Stefan Bayer, Daniel Berning, Philippe Blank, Wolfgang Pelzer, Michael Pfoser, Björn Wilden
  • Patent number: 10617826
    Abstract: An assembly for a drug delivery device is provided comprising a housing, and a lead screw having a longitudinal axis, a distal end and a proximal end, the lead screw being rotatably fixed during dose setting and dose delivery and axially movable in a distal direction relative to the housing, the lead screw further including a thread. The assembly further comprises a drive nut threadedly engaged with and screwable along the lead screw thread and a dial link connected with the drive nut and axially movable and rotatably fixed relative to the drive nut, where the dial link comprises a first portion of a feedback ratchet. The assembly is configured such that, during dose delivery, the assembly generates a feedback signal.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: April 14, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Blancke, Axel Teucher, Michael Jugl, Christiane Schneider
  • Patent number: 10603443
    Abstract: A driving and dosing device for an injection device for discharging a liquid product includes a housing, a rotatable dose adjustment member for adjusting a product dose to be discharged, a driven member received in the housing, a driving member rotatable relative to the housing and which, during the discharge of product, is coupled to the driven member such that a rotation of the driving member has the effect that the driven member is moved in the distal direction relative to the housing, a pretensioned driving spring which is switched between the dose adjustment member and the driving member during the adjustment of the product dose, wherein the dose adjustment member, during the adjustment of the product dose, is coupled in a rotationally fixed manner to the driving member, such that a rotation of the driving member relative to the dosing member is prevented.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: March 31, 2020
    Assignee: TecPharma Licensing AG
    Inventors: Susanne Schenker, Ursina Streit, Patrick Hostettler
  • Patent number: 10596332
    Abstract: the present invention relates to a device for a medicament delivery device, which extends along a longitudinal axis and comprises a medicament delivery member cover (18) arranged at a proximal end thereof; wherein the device comprises a delivery member protruding adjuster (28) operably connected to said medicament delivery member cover (18). The invention is characterised in that the device further comprises a signal generating mechanism (34) operably connected to said delivery member protruding adjuster (28) and arranged to provide an audible and/or tactile and/or visual signal indicating that a certain penetration depth has been set.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: March 24, 2020
    Assignee: SHL MEDICAL AG
    Inventor: Gunnar Elmen
  • Patent number: 10589029
    Abstract: An adjustable needleless injection system for subcutaneous injection of a liquid medication to a patient is disclosed. The adjustable needleless injection system may include: a medication cartridge that holds the liquid medication, where the medication cartridge includes a cartridge piston, a spring-actuated injector that may be coupled with the medication cartridge and configured to selectively apply force to the cartridge piston, and a charging mechanism configured to charge the spring-actuated injector based on a body type of the patient.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: March 17, 2020
    Inventor: Soheila Salahshoor Kordestani
  • Patent number: 10576212
    Abstract: The present disclosure is generally directed to a dose setting mechanism and a drug delivery device herewith, i.e. a handheld injection device for selecting and dispensing a number of user variable doses of a medicament. The dose setting mechanism comprises a dose setting member rotatable relative to a housing in a first direction for dose setting and in an opposite second direction for dose correcting, a cam ring and a coupling member coupled to a drive member. A ramped interface is provided between the dose setting member and the cam ring such that rotation of the dose setting member relative to the cam ring in the second direction causes axial displacement of the cam ring.
    Type: Grant
    Filed: February 8, 2015
    Date of Patent: March 3, 2020
    Assignee: Sanofi
    Inventors: William Geoffrey Arthur Marsh, Matthew Meredith Jones
  • Patent number: 10561796
    Abstract: Apparatus and methods for providing controlled pressure-flow pulses which purge a catheter system with turbulent flow flushing. Accomplishment of such controlled pressure-flow pulses is provided by a variety of inventive devices including a special plunger rod for a conventional syringe, other interactive parts for conventional syringes, an in-line catheter attachable device which automatically generates the controlled pressure-flow pulses and also single pulse, digitally operated devices.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: February 18, 2020
    Assignee: Beckton, Dickinson and Company
    Inventors: Michael W. Howlett, James V. Mercer, Amelio Paolucci
  • Patent number: 10549046
    Abstract: A drive mechanism (1) for use in a drug delivery device (100) is provided. The drive mechanism (1) comprises a housing (10, 11, 12, 14, 15) with a proximal and a distal end and a piston rod (22) which is rotatable with respect to the housing (10, 11, 12, 14, 15). The drive mechanism (1) further comprises a nut member (31) which is selectively rotationally lockable with respect to the housing (10, 11, 12, 14, 15), wherein the drive mechanism (1) is switchable between a setting mode of operation and a dispensing mode of operation.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: February 4, 2020
    Assignee: Sanofi
    Inventors: Simon Lewis Bilton, Robert Veasey, Matthew Jones, David Aubrey Plumptre, William Marsh, Michael Bainton, Daniel David Higgins
  • Patent number: 10507289
    Abstract: A medicament delivery device is presented having a housing, a medicament container holder, arranged movable in relation to the housing and capable of accommodating a medicament container. An activator is arranged in the housing and capable of, upon activation, acting on a medicament container for expelling a dose of medicament, where the activator has a plunger rod, a manually operable dose setting nut rotatably connected to the housing and arranged with first threads. Second threads are arranged on the medicament container holder being arranged to cooperate with said dose setting nut, wherein operation of the dose setting nut will cause the medicament container holder with the medicament container to move towards the plunger rod for setting a dose of medicament to be delivered.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: December 17, 2019
    Assignee: SHL MEDICAL AG
    Inventors: Kasper Enge, Gunnar Elmén, Anders Holmqvist
  • Patent number: 10471217
    Abstract: An assembly for a drug delivery device is provided, the assembly comprising a feedback feature. The feedback feature is configured to indicate an end of the dispense operation to a user by giving an audible and/or tactile feedback.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: November 12, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: David Aubrey Plumptre, Naceur Rekaya, Paul Richard Draper, Paul Griffin, Stephen Francis Gilmore
  • Patent number: 10463801
    Abstract: A method for assembling a drive spring, especially into a drug delivery device includes rotating a component part to which the drive spring is attached in a first direction, followed by a rotation of the component part in the opposite direction and followed by attachment of a rotational stop. Further, the disclosure includes a drug delivery device for selecting and dispensing a number of user variable doses of a medicament, which device comprises a pre-charged drive spring.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: November 5, 2019
    Assignee: Sanofi
    Inventors: William Marsh, Anthony Paul Morris, Matthew Jones, Samuel Steel
  • Patent number: 10449301
    Abstract: An assembly for a drug delivery device is provided, the assembly comprising an actuator which is configured to be operated in order to dispense a dose of medication and a feedback feature being configured to give a feedback signal to a user at the end of a dwell period after the actuator has reached an end position.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: October 22, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: David Aubrey Plumptre, Naceur Rekaya, Paul Richard Draper, Paul Griffin, Stephen Francis Gilmore
  • Patent number: 10357616
    Abstract: An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement. Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: July 23, 2019
    Assignee: Novo Nordisk A/S
    Inventors: Claus Schmidt Moller, Bo Radmer, Lars Ulrik Nielsen, Christian Peter Enggaard
  • Patent number: 10350359
    Abstract: A dosing device for an injection device, the dosing device including an actuating element for adjusting and/or dispensing a dose from the injection device, a thrust element for generating a forward movement for discharging a dose and a coupling to which the actuating element and the thrust element are coupled such that a rotational movement of the actuating element is transmitted directly to the thrust element and an axial movement of the actuating element is different than an axial movement of the thrust element.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: July 16, 2019
    Assignee: TecPharma Licensing AG
    Inventors: Stefan Burren, Jürg Hirschel, Samuel Martinoia, Ulrich Moser, Markus Tschirren
  • Patent number: 10328209
    Abstract: An assembly (100) for a drug delivery device is presented. The assembly comprises a housing (10) with a main axis (X), a dose setting member (2) being rotatable with respect to the housing (10) for setting a dose of a drug, an activation member (1) being axially movable with respect to the housing (10) for dispensing the dose from the drug delivery device, and a rotation member (5) being arranged between the activation member (1) and the dose setting member (2). The assembly (100) is configured such that the rotation member (5) is rotatable with respect to the dose setting member (2) and the activation member (1), wherein the outer surface (21) of the assembly (100) comprises the outer surface (22) of the rotation member (5).
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: June 25, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Torsten Kraft, Markus Oschmann
  • Patent number: 10328211
    Abstract: An automatic accurate dose syringe includes a barrel, a plunger seal, a barrel adapter assembly having a barrel tip and a needle, and a dose control mechanism having a plunger having a coarse pitch screw on its exterior surface, a housing having a corresponding coarse pitch guide along the interior surface of the housing, a screw having a fine pitch screw which interfaces with a fine pitch nut of an adapter, wherein the plunger has an internal annular space within which screw at least partially resides. The syringe further includes a locking mechanism, an activation button, and a biasing member such as a compression and/or a torsional spring. The components are configured such that actuation of the activation button by the user manipulates the locking mechanism to permit the biasing member to move from an initial energized state to a lower energy state, thereby automating drug delivery from the syringe.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: June 25, 2019
    Assignee: UNL Holdings LLC
    Inventors: Gautam N. Shetty, Lou Castagna
  • Patent number: 10307541
    Abstract: A drive mechanism of a drug delivery device for dispensing of a dose of a medicament includes a housing extending in an axial direction, and a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction. The drive mechanism further includes a last dose sleeve rotatably supported in the housing and being selectively engageable with a dose setting mechanism for setting of a dose, and a last dose member threadedly engaged to the housing, rotatably locked to the last dose sleeve and axially displaceable relative to the last dose sleeve.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: June 4, 2019
    Assignee: Sanofi
    Inventors: Stefan Bayer, Daniel Berning, Philippe Blank, Wolfgang Pelzer, Björn Wilden
  • Patent number: 10300212
    Abstract: A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: May 28, 2019
    Assignee: ANTARES PHARMA, INC.
    Inventors: Janice L. Cox, Matthew H. Rust, Thomas E. Kramer, Peter A. Hoeft
  • Patent number: 10265480
    Abstract: A multiple dose syringe has a first valve defining a first valve opening pressure and a second valve defining a second valve opening pressure. A storage chamber in fluid communication with the second valve stores multiple doses of a substance therein and includes an outlet for dispensing multiple doses of the stored substance therethrough. A compression surface is movable between first and second positions and defines a compression chamber between the compression surface and the first valve. Movement of the compression surface in a direction from the first position toward the second position dispenses substance in the compression chamber through the first valve and out of the syringe. Movement of the compression surface in a direction from the second position toward the first position causes substance to flow from the storage chamber through the second valve and into the compression chamber.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: April 23, 2019
    Assignee: DR. PY INSTITUTE LLC
    Inventor: Daniel Py