Having Means For Metering Material Flow To Or From Body Patents (Class 604/207)
-
Patent number: 9011390Abstract: Methods and devices for micro-dosing a liquid are disclosed herein. According to one embodiment, a method for a time controlled micro-dosing of a liquid from a liquid reservoir includes: receiving the liquid reservoir with a structure wherein the structure is portable; securing the liquid reservoir to the structure; connecting a second end of a drive unit to a piston disposed within the liquid reservoir; activating a drive motor; displacing the drive unit with respect to the structure towards the piston in an axial direction with the drive motor; moving the piston axially within the liquid reservoir; and micro-dosing the liquid from the liquid reservoir.Type: GrantFiled: March 14, 2013Date of Patent: April 21, 2015Assignee: Roche Diagnostics International AGInventors: Roger Haenggi, Hanspeter Niklaus
-
Publication number: 20150105732Abstract: The present invention relates to an injection device (1) for setting and injecting set doses from a held drug cartridge (10). The injection device (1) comprises a housing (110,120,130, 140), a piston rod (800), a rotatable driver (500, 700) and a dose setting device (400). The dose setting device (400) comprises a predetermined stop to limit the amount of an expelled dose corresponding to the amount of a set dose. A secondary stop limiter includes first (700) and second (270) components and a secondary stop track follower (950) arranged between the first (700) and second (270) components. If the predetermined stop fails to stop the driver (500, 700) at the end of injection, the secondary stop track follower (950) moves towards a safety stop (708) to prevent the driver (500, 700) from rotating further.Type: ApplicationFiled: March 15, 2013Publication date: April 16, 2015Inventors: Bastian G. Kjeldsen, Brian Mouridsen, Jim Radmer
-
Patent number: 9005171Abstract: A resettable dosing mechanism comprises a dose button and a dial grip operatively coupled to the dose button. A spindle acts on a bung of a cartridge and a driver is operatively coupled between the dose button and the spindle. During an injection of the dose, the dose button moves in an axial direction to cause the spindle to administer the dose. During resetting of the dose setting mechanism, the spindle is retracted back into the dose setting mechanism. An advantageous resetting mechanism is described.Type: GrantFiled: May 28, 2010Date of Patent: April 14, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventor: Christopher Jones
-
Publication number: 20150099966Abstract: An anesthetic administration device comprising an infusion device, which is in fluid connection with a regional anesthetic needle by means of a feed tube. The infusion device comprises one or more anesthetic flow devices capable of triggering forward flow, and optionally backward flow, of the local anesthetic through the regional anesthetic needle. Forward, and optionally backward flow, of the local anesthetic through the regional anesthetic needle is controlled by a controller that comprises one or more actuator switches. The one or more actuator switches are positioned on the device such that they may be operated by hand.Type: ApplicationFiled: April 24, 2013Publication date: April 9, 2015Inventors: Peter Jeffrey Young, Joseph Joachim Carter, Emad Eldin Fahmy Fawzy, John Edward Gibson
-
Publication number: 20150094667Abstract: A syringe having a longitudinal axis, comprising: a barrel assembly including: a barrel, extending longitudinally between a proximal end and a distal end, a collar, provided at the proximal end of the barrel, and defining a reading window; a plunger including: a longitudinally extending graduation portion that is at least partially longitudinally slidably received in the barrel, and that provides for at least two mutually different visually readable graduations, which respective graduations extend along the longitudinal axis and are alternatively selectable by rotation of the graduation portion around the longitudinal axis, such that a selected graduation is visible through the reading window when the plunger is slid into and out of the barrel during use.Type: ApplicationFiled: July 2, 2014Publication date: April 2, 2015Inventors: Franciscus Maria Verhoeven, Andreas Adrianus Lambertus van den Houdt, Angelinus Quirinus Maria de Beer
-
Patent number: 8992484Abstract: An injection device including a dose setting assembly, and an injection assembly, wherein operating the dose setting assembly to set a dose causes an engagement element to pass a tooth on a toothed rod in a combined translational and rotational movement.Type: GrantFiled: July 23, 2010Date of Patent: March 31, 2015Assignee: Novo Nordisk A/SInventors: Bo Radmer, Kristian Glejbøl, Jonas Torry-Smith, Tom Hede Markussen, Lars Morten Bom, Christian Peter Enggaard, Sara Juana Niemann, Martin Ebro
-
Patent number: 8992487Abstract: An injection device for dispensing a product, the injection device including a moveable element which is moved for a dispensing operation, a spring, a product container holder and a product container, wherein the spring pushes against the moveable element to move the moveable element to an initial position after the dispensing operation has ended and against the product container to seat the product container in the product container holder.Type: GrantFiled: August 26, 2010Date of Patent: March 31, 2015Assignee: TecPharma Licensing, AGInventors: Adrian Eich, Aurèle Horisberger, Patrick Hostettler, Malte Kladiwa, Stefan Meier, Peter Stettler, Jürgen Wittmann
-
Patent number: 8986261Abstract: A resettable drug delivery device includes a body, a cartridge holder for receiving a cartridge, and a releasable coupling connecting the cartridge holder to the body or the dose setting mechanism. During an initial rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a first axial direction relative to the body or the dose setting mechanism and during a continued rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a second, contrary axial direction.Type: GrantFiled: March 22, 2012Date of Patent: March 24, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventors: David Aubrey Plumptre, Christopher James Smith
-
Patent number: 8986260Abstract: A dose setting mechanism comprising a dose setting member and a drive member for driving a piston rod in a distal direction during dose dispensing. The drive member comprises a proximal drive member and a distal drive member. A first clutch releasably coupling the proximal drive member and the distal drive member. A spring means biases the proximal drive member and the distal drive member in the coupled state during dose setting and dose dispensing. Engaging means are provided associated to the proximal drive member and to the dose setting member, wherein the engaging means are designed and arranged such that the proximal drive member entrains the dose setting member in the distal direction during dose setting but allows a relative axial movement of the proximal drive member with respect to the dose setting member in the proximal direction.Type: GrantFiled: March 22, 2012Date of Patent: March 24, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventor: David Aubrey Plumptre
-
Publication number: 20150080811Abstract: A medicament delivery device includes a housing having proximal and distal ends; a hollow piston plunger within the housing; a telescopic dose drum concentric between the housing and the plunger; and a plunger driver to drive the plunger toward the proximal end having a hollow drive drum sleeve movable within and coupleable to the piston plunger and fixed to the dose drum; an actuator operably connected to the drive drum sleeve; and a stop body for inhibiting rotation of the dose drum and drive drum sleeve when a set dose equals a remaining dose in a medicament container. The drive drum sleeve and piston plunger are operatively coupled such that axial movement of the actuator toward the proximal end forces the drive drum sleeve and piston plunger to couple, whereby the piston plunger and dose drum are displaced toward the proximal end for delivering the set dose.Type: ApplicationFiled: April 9, 2013Publication date: March 19, 2015Applicant: CAREBAY EUROPE LTDInventor: Anders Wieselblad
-
Publication number: 20150080807Abstract: A self-injection device includes a visual indicator for visually indicating that a main body and a cartridge holder are properly connected to each other. In one embodiment, the visual indicator includes a visual marking on the cartridge holder and a visual marking on the main body, such that when the cartridge holder and the main body are properly connected, the visual markings are aligned with each other. A self-injection device that includes an indicator for a dose window is also disclosed.Type: ApplicationFiled: April 12, 2013Publication date: March 19, 2015Applicant: Becton, Dickinson and CompanyInventors: Jared Schneider, Mark Guarraia, Margaux Boyaval, Ryan Shafer
-
Patent number: 8979791Abstract: A medicated module comprising a connecting body configured for attachment to a drug delivery device. A first needle is fixed within the connecting body and an outer body operatively coupled to the connecting body. A needle guard operatively coupled to the outer body and a biasing member positioned between the outer body and needle guard. A second needle fixed within the outer body and a recess within the connecting body defines a reservoir. The reservoir contains at least one dose of a medicament and is configured for fluid communication with the first and second needle.Type: GrantFiled: June 1, 2010Date of Patent: March 17, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventors: James Alexander Davies, Steven Wimpenny, Daniel Thomas De Sausmarez Lintell, Malcolm Stanley Boyd, Naceur Rekaya, Simon Lewis Bilton, John David Cross
-
Publication number: 20150073355Abstract: Dosing device for an administration device with a limiting mechanism, comprising a first limiting means (50) with a first stop means (52), a second limiting means (30) with a second stop means (32), wherein the second limiting means follows movements of the first limiting means during dosing movements with a defined transmission ratio, and wherein the first and the second stop means each describe a path curve by their movements in such a manner that the two path curves intersect in at least one point or come so close together that the stop means contact one another in a stop position, whereby a blocking of the movement of the limiting means relative to each other during dosing movements can be effected in that the respective path curves described by the first and second stop means are closed and can be run through preferably multiple times by the first stop means, by the second stop means or by both stop means until the stop means contact one another at the stop position.Type: ApplicationFiled: November 12, 2014Publication date: March 12, 2015Inventors: Jürg Hirschel, Ulrich Moser
-
Patent number: 8974423Abstract: A resetting mechanism for a reusable drug delivery device. The device comprises a spindle and a spindle guide engaging the spindle. During a resetting step of the resetting mechanism, the spindle rotates while the spindle guide does not rotate.Type: GrantFiled: May 27, 2010Date of Patent: March 10, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventors: David Aubrey Plumptre, Christopher John Jones
-
Publication number: 20150065991Abstract: Vial dosing systems and methods are disclosed. A vial dosing device includes a connecting body coupleable to a vial, a cannulated plunger having a proximal end coupled to the connecting body, a dose chamber adapted to slidably receive a distal end of the cannulated plunger and to expel medicament through a distal end of the dose chamber, and a plunger tip check valve coupled to the cannulated plunger and adapted for fluid flow from the cannulated plunger through the plunger tip check valve into the dose chamber.Type: ApplicationFiled: April 8, 2013Publication date: March 5, 2015Applicant: BECTON, DICKINSON AND COMPANYInventors: James Bates, Doug Lawrence, Edward Rosen, Robert Banik
-
Publication number: 20150065963Abstract: The present invention relates to an injection device (1) for setting and injecting set doses from a held drug cartridge (10). The injection device (1) comprises a housing (110, 120, 130, 140), a piston rod (800), a rotatable driver (500, 700) and a dose control member (350). A stored energy source (560) is configured to drive rotation of the driver (500, 700) to cause the piston rod (800) to expel a set dose. The dose control member (350) rotates during dose setting and during dose expelling. A first clutch (C1) is arranged between the dose control member (350) and the driver (500, 700). A second clutch (C2) is arranged between the driver (500, 700) and the housing (110, 120, 130, 140) to control the expelling movement. During dose setting the first clutch (C1) is disengaged and the second clutch (C2) is engaged. During dose expelling the first clutch (C1) is engaged and the second clutch (C2) is disengaged.Type: ApplicationFiled: March 15, 2013Publication date: March 5, 2015Inventors: Bastian G. Kjeldsen, Brian Mouridsen
-
Patent number: 8968255Abstract: An improved drug delivery device is provided having a piston rod that incorporates on its proximal end at least one guidepost that is configured for transmitting axial and rotational forces from a drive mechanism. The device comprises a drug delivery device housing and a medicament contained in the drug delivery device housing.Type: GrantFiled: March 26, 2010Date of Patent: March 3, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventor: Philip Oakland
-
Patent number: 8968257Abstract: A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5?, 6, 6?) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27?, 28?) on the distal end of a cartridge assembly (20).Type: GrantFiled: April 21, 2011Date of Patent: March 3, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventors: Uwe Dasbach, Steffen Raab, Michael Harms, Udo Stauder, Volker Korger
-
Publication number: 20150057616Abstract: At least one hand-held injection device for the metered injection of a liquid drug into a person's tissue is disclosed. The exemplary injection device comprises an elongated drug reservoir having a longitudinal reservoir axis (A), an elongated dosing unit having a dosing unit inlet, a dosing unit outlet, and a metering cavity, the dosing unit having a longitudinal dosing unit axis (A?), the elongated drug reservoir being fluidically coupled to the dosing unit inlet. The dosing unit and the drug reservoir are arranged such that the longitudinal dosing unit axis (A?) is in parallel alignment with the reservoir axis (A). The dosing unit structured to allow the flow of the liquid drug from the drug reservoir into the metering cavity via the dosing unit inlet, thus charging the metering cavity, and to subsequently discharge the metering cavity by dosing drug out of the metering cavity into the dosing unit outlet.Type: ApplicationFiled: February 25, 2014Publication date: February 26, 2015Applicant: Roche Diagnostics Operations, Inc.Inventors: Oliver Shergold, Simon Scheurer
-
Patent number: 8961472Abstract: The present invention relates to a method for the assembly of drug delivery devices, in particular of pen-type drug delivery devices, having a dose dial mechanism and a drive mechanism, enabling the administration of medicinal products from a multidose cartridge and the drug delivery devices obtainable according to the said method.Type: GrantFiled: March 1, 2007Date of Patent: February 24, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventors: Robert Veasey, Steven Wimpenny
-
Patent number: 8961473Abstract: A drive mechanism for a drug delivery device comprises a housing having a proximal end and a distal end and a piston rod, which is adapted to be displaced in a distal direction with respect to the housing when dispensing a drug dose. A drive member is adapted to be rotated when dispensing the drug dose, wherein the drive mechanism is configured to convert rotational movement of the drive member into a movement of the piston rod in the distal direction with respect to the housing. A stop member is adapted to prevent a rotational movement of the drive member with respect to the housing when setting a drug dose.Type: GrantFiled: July 22, 2013Date of Patent: February 24, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventor: Michael Heald
-
Publication number: 20150051580Abstract: An auto-injector device for administering a liquid pharmaceutical composition, in which an end-user can select between doses that the device is capable of delivering. The end-user choices that translate into the selected doses can be based on end-user perceived severity of symptoms, end-user weight and other such factors. In some embodiments the auto-injector is configured to administer the one chosen dose only. In other embodiments, the auto-injector can deliver second and subsequent doses up to full dose of the pharmaceutical composition disposed in the injector. The auto-injector can provide visual, audio, and tactile feedback, alone or in combination, to the user to indicate the dose selected, instructions for use, and when the dose has been administered.Type: ApplicationFiled: August 18, 2014Publication date: February 19, 2015Applicant: Dr. Reddy's Laboratories, Ltd.Inventors: Adam M. Shain, Rajesh Kumar, Anil Namboodiripad
-
Patent number: 8956332Abstract: A drug delivery device for dispensing of a dose of a medicinal product comprises a housing having a proximal end and a distal end, a container of medicinal product having a piston retained within, and a push-pull element, where the push-pull element is displaceable in proximal direction for setting of a dose and is displaceable in distal direction for dispensing of a dose. The drug delivery device may further include a piston rod coupled with the housing and with the push-pull element and coupling elements for converting a proximal displacement of the push-pull element into a rotational movement of the piston rod and for converting a distal displacement of the push-pull element into an axial movement of the piston rod with respect to the housing.Type: GrantFiled: July 5, 2010Date of Patent: February 17, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventors: Axel Teucher, Axel Forstreuter
-
Publication number: 20150038915Abstract: The present invention relates to an injection device for automatic spring driven injection of a liquid drug. The injection device has a dose setting mechanism by which doses of an individual size can be set by a user, and a mechanical dose size display for displaying the size of the set dose. A housing (2) defines an interior space and has a longitudinal window (3) through which a rotatable scale drum (20) can be viewed. The scale drum (20) is coupled to a rotatable dose dial button (10) which is axially retained in relation to the housing (2) and by which the individual doses can be set.Type: ApplicationFiled: January 17, 2013Publication date: February 5, 2015Applicant: NOVO NORDISK A/SInventor: Simon M. Pedersen
-
Patent number: 8945069Abstract: An injection device (1) for administering a fixed dose of a medication is provided. The injection device (1) comprises a housing (2) wherein a drive mechanism comprising a drive member (3) is at least partially enclosed and a dosing element (34) which is fixed relative to the drive member (3). Here, a dose can be set by rotating the dosing element (34) relative to the housing (2) in a dose setting direction (s) and the dose can be dispensed by pushing the dosing element (34) towards the housing (2). Moreover, a method is provided for operating an injection device (1) for the administration of a fixed dose of a medication: A dose can be set by rotating a dosing element (34), a dose can be dispensed by pushing the dosing element (34) towards the housing (2) and a dose can be cancelled by rotating the dosing element (34) in a direction opposite to the dose setting direction (s).Type: GrantFiled: December 18, 2009Date of Patent: February 3, 2015Assignee: Sanofi-Aventis Deutschland GmbHInventors: David Plumptre, Christopher James Smith
-
Publication number: 20150032063Abstract: A self-closing slit valve which is opened by compression inside a receiving tapered female orifice. For luer fittings, internal taper of a female luer fitting provides sufficient distortion of an asymmetrical valve to distort a closed, preferably planar slit to a patent fluid pathway. The slit may be opened by valve displacement into a tapered female connector orifice or by being forced open by a blunt cannula. The valve may be effectively used as a valving part in needleless connector adapters. A special method for constructing the valve when imposed upon by restrictive tolerances of a luer fitting is also disclosed. Examples of uses of the self-closing valve in male luer needleless connector adapters and closed mixing systems and closed mixing systems with flush are also disclosed. An application providing a closed male luer adapter, a closed valved male luer replacement for a syringe is disclosed as well as applications associated with closed system mixing syringes.Type: ApplicationFiled: October 7, 2014Publication date: January 29, 2015Inventor: Gale Harrison Thorne
-
Patent number: 8939944Abstract: A product dispensing apparatus including a reservoir module, a dosing module and a dose setting member. The reservoir module includes a front casing section, a block, a first connector, a piston, and a piston rod moveable in a dispensing movement and against the dispensing movement, and including a return block engageable with the block, wherein engagement between the block and the return block prevents the piston rod from moving against the dispensing movement. The dosing module includes a rear casing section, including a second connector which is engageable with the first connector to form a detachable connection between the reservoir module and the dosing module, and a dosing and drive device. The dose setting member engages the piston rod such that it is moveable together with and in the same direction as the piston rod during the dispensing movement and is moveable relative to the piston rod against the dispensing movement.Type: GrantFiled: August 9, 2007Date of Patent: January 27, 2015Assignee: TecPharma Licensing AGInventors: Roney Graf, Fritz Kirchhofer
-
Patent number: 8939959Abstract: A simple method and device enabling a unit dose from a reservoir is provided. The dose is drawn into the reservoir and is then expelled from the device by depressing a plunger. The plunger has features which divide the dose into discrete intervals. As the plunger is moved during delivery, the features on the plunger and features connected to a barrel interact to provide for intermittent stops to the delivery. Other aspects of the device provide for reduced dead space, safety and selective interconnection with other devices. Thus, the device divides the dose.Type: GrantFiled: June 20, 2013Date of Patent: January 27, 2015Assignee: Becton, Dickinson and CompanyInventors: Bruno Baney, Colin May, Patrick Dupuis, Frederic Perot
-
Publication number: 20150025474Abstract: Described is a medicament delivery device comprising a housing having a distal end adapted to engage a removable needle assembly, a dosing mechanism coupled to the housing, and a sleeve coupled to the housing and having a distal end with one or more projections. Movement of the dosing mechanism causes axial translation of the sleeve relative to the housing and causes the one or more projections to extend from a retracted position relative to the housing beyond the distal end of the housing to disengage the removable needle assembly from the housing.Type: ApplicationFiled: February 6, 2013Publication date: January 22, 2015Inventors: Stephan Riedel, Hans-Rainer Drieschmanns, Silke Loy
-
Publication number: 20150018772Abstract: A driving and dosing device for an injection device includes: a housing, a dosing element gripped by a user, an actuating element actuable by the user to discharge the set dose, a propulsion element for acting on a piston to discharge the set dose, a spring configured to act between the propulsion element and an abutment, which is preloaded so as to discharge a maximum dischargeable product quantity in a plurality of individual discharges, a rotation element configured to rotate relative to the housing and a clutch configured for releasably engaging the rotation element. Releasing the clutch permits the rotation element to rotate relative to the housing when the actuating element is actuated, blocks the rotation of the rotation element relative to the housing when the actuating element is released, and by rotation of the rotation element, the spring is permitted to move the propulsion element in the discharge direction.Type: ApplicationFiled: September 30, 2014Publication date: January 15, 2015Inventors: Susanne Schenker, Ursina Streit
-
Publication number: 20150018776Abstract: A driving and dosing device for an injection device configured for dose setting and dose administration includes: a housing, a dose indicating element including a circumferential dose scale, a pointing device and a dosing element gripped by a user. In order to set the dose to be administered, the dosing element is rotatable such that the dose indicating element is rotatable or screwable about an axis of rotation relative to the pointing device, and a value of the dose scale that corresponds to the set dose is readable by means of the pointing device. A bearing element, with which the dose indicating element is in an engagement, causes the rotational or screwing motion of the dose indicating element relative to the pointing device, characterized in that the bearing element can be moved together with the dose indicating element relative to the housing and along the axis of rotation.Type: ApplicationFiled: September 30, 2014Publication date: January 15, 2015Inventors: Susanne Schenker, Ursina Streit
-
Publication number: 20150018775Abstract: A monitoring device for monitoring operation of a drug delivery device and to a respective drug delivery device is presented in which a fastening member releasably attaches the monitoring device to an axially elongated housing of the drug delivery device, a sliding member is shiftable relative to the fastening member in an axial direction and being adapted to operably engage with at least one dose setting component of the drug delivery device to follow an axial displacement of the dose setting component relative to the housing component, a first sensor arrangement for detecting a rotation of the dose setting component relative to the fastening member, a second sensor arrangement for detecting an axial displacement of the sliding member relative to the fastening member, and a processing member coupled to the first and to the second sensor arrangements to process first and second signals obtainable from the first and from the second sensor arrangements for determining the size of a dose dispensed by the drug deType: ApplicationFiled: February 8, 2013Publication date: January 15, 2015Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Jasmin Groeschke, Alexander Allerdings, Jan-Peter Spengler, Christoph Dette, Matthias Scharf, Andreas Bode, Michael Schrack
-
Patent number: 8932267Abstract: An inflatable face seal (1?; 30?) for a respiratory mask, the inflatable face seal comprising an annular air-tight hollow portion (12?; 40?) where a cross section through one section of the annular hollow portion (12; 40) comprises a bonded joint (11; 41) which joins two overlapping flanges (6,7; 35,36). The two flanges are bonded together such that an inwardly facing surface (10; 39) of a first flange (6; 35) of the two overlapping flanges is in contact with an outwardly facing surface (9; 38) of a second flange (7; 36) of the two overlapping flanges. In this way, the bond is strong and only exposed to shear stresses when the annular air-tight hollow portion is exposed to increased pressure.Type: GrantFiled: January 2, 2007Date of Patent: January 13, 2015Assignee: AMBU A/SInventor: Christian Grane
-
Patent number: 8926568Abstract: A medicament delivery device includes a housing for a medicament container assembly; a drive member interactively connected to the assembly for expelling a dose of medicament; a dose actuation assembly operably connected to the drive member; and an actuation member interactively connected to the housing and the dose actuation assembly by a gear assembly. The actuation member is movable generally perpendicularly to a longitudinal axis of the device from an initial position, in which the actuation member is positioned within the housing, to a dose-set position, in which a portion of the actuation member protrudes a distance proportional to the set dose from the longitudinal surface of the housing when the dose actuation assembly. The actuation member is manually operated in a direction generally perpendicular to the longitudinal axis of the device from the dose-set position to the initial position for driving the dose actuation assembly and drive member.Type: GrantFiled: May 9, 2011Date of Patent: January 6, 2015Assignee: SHL Group ABInventor: Anders Holmqvist
-
Patent number: 8920383Abstract: A mechanism for preventing setting of a dose, which exceeds the amount of a medicament in a reservoir in an injection device. The device comprises a threaded piston rod, a limiter and a driver. The three elements are arranged such that during dose setting, the limiter is moved towards an end-of-contend position, wherein dose setting is limited. The invention comprises an accumulative and a non-accumulative embodiment. The invention further relates to a mechanism for prevention ejection of a dose exceeding the set dose.Type: GrantFiled: July 17, 2006Date of Patent: December 30, 2014Assignee: Novo Nordisk A/SInventors: Christian Peter Enggaard, Claus Schmidt Moller, Tom Hede Markussen
-
Patent number: 8915887Abstract: An injection device is disclosed which comprises a housing (10) with a display for showing the size of a set dose. The display is formed from a number of individual ciphers (11, 40) which each comprises a plurality of segments (13, 14) extending horizontally and vertically. At the end of the injection device a dose setting element (20) is provided for allowing the user to set the size of the dose to be injected. Further, the display mechanism comprises a first pattern (35) for showing the vertical segments (14), and a second pattern (25) for showing the horizontal segments (13). The patterns (25, 35) are associated with the dose setting button (20) and arranged to be moved when the dose setting button (20) is operated. The injection device disclosed can have any number of ciphers (11, 40) which is coupled to each other in order to show to the user the size of any dose set.Type: GrantFiled: March 29, 2012Date of Patent: December 23, 2014Assignee: Novo Nordisk A/SInventor: Mikkel Avlund
-
Patent number: 8911402Abstract: A drug delivery device comprising: a device body, an operating member which is configured to be movable relative to the device body for operating the drug delivery device, a preventing member which prevents movement of the operating member relative to the device body for operating the drug delivery device, wherein the preventing member is removable to allow movement of the operating member relative to the device body for operating the drug delivery device.Type: GrantFiled: September 29, 2010Date of Patent: December 16, 2014Assignee: Sanofi-Aventis Deutschland GmbHInventors: Robert Veasey, Garen Kouyoumjian, Christopher Jones, Catherine Anne Macdonald, Marcus James Blachford, James Andrew Holt
-
Patent number: 8905977Abstract: A surgical stapling and severing instrument enables minimally invasive surgical procedures by having upper and lower jaws (i.e., anvil and staple channel) that are positioned with an elongate shaft and handle through a surgical opening, and in particular through a cannula of a trocar. A pair of fluid bladders (lift bags) are positioned in the staple channel beneath a proximally projecting lever tray so that transfer of fluid from the handle causes closing and clamping of the anvil. The bi-directional fluid control may be mechanically produced at the handle or by activating an electroactive polymer actuator. Once firing is sensed, an EAP plunger in a medical substance syringe inserted into the elongate shaft is activated to dispense a medical substance (e.g., anesthetics, adhesives, cauterizing substances, antibiotics, etc.) and is guided along a firing bar to a cutting surface of an E-beam placing the substance on tissue as severed.Type: GrantFiled: June 1, 2005Date of Patent: December 9, 2014Inventors: Frederick E. Shelton, Joseph C. Hueil, Jerome R. Morgan
-
Patent number: 8905970Abstract: A high pressure delivery device for delivering a medicament includes a first chamber for storing a supply of the medicament and a second chamber in fluid communication with the first chamber. A fluid connection path is in fluid communication with the second chamber for administering the medicament. A valving system is in fluid communication with the first chamber, the second chamber and the fluid connection path. The valving system allows a dose of the medicament to be injected from the first chamber into the second chamber while substantially preventing backflow of the dose into the first chamber and substantially preventing leakage through the fluid connection path. The valving system also allows the dose in the second chamber to be administered through the fluid connection path while substantially preventing the dose from flowing back into the first chamber.Type: GrantFiled: July 17, 2009Date of Patent: December 9, 2014Assignee: Becton, Dickinson and CompanyInventors: James Bates, Robert Banik, Barry Ginsberg
-
Patent number: 8900203Abstract: The present invention relates to a drug delivery device for dispensing of a predefined dose of a medicinal product, comprising: a housing, a cartridge holder adapted to receive a cartridge containing the medicinal product to be dispensed, the cartridge holder being connectable to the housing, a drive mechanism to be operably engaged with the cartridge for setting and/or dispensing of a predefined dose of the medicinal product, wherein the drive mechanism is axially slidingly supported in the housing for compensating axial clearance between the drive mechanism and the cartridge and wherein the drive mechanism is axially fixable relative to the housing.Type: GrantFiled: October 8, 2010Date of Patent: December 2, 2014Assignee: Sanofi-Aventis Deutschland GmbHInventors: Michael Helmer, Claudia Matthias, Leo Zeimetz, Reza Shahbazfar, Benjamin Schaefer, Carsten Mosebach
-
Publication number: 20140350478Abstract: The present invention relates to an automatic torsion spring based injection device having a dial-up/dial-down mechanism by which a dose can be set by rotating a dose setting member in a first direction and which dose size can be reduced by rotating the same dose setting member in a second and opposite direction. The dial-up/dial-down mechanism operates a torsion spring which is strained when setting a dose and unstained when rotating the dose setting element in the second direction.Type: ApplicationFiled: December 20, 2012Publication date: November 27, 2014Inventors: Torben S. Hansen, Hans Hemmingsen, Christian H. Nielsen, Ebbe Kiilerich, Mikkel Avlund, Matias Melander
-
Patent number: 8888750Abstract: A pen-type injector is improved so that a user may select a delivery dose of a medicinal product from a multidose cartridge. The injector includes a housing, the cartridge containing the medicinal product retained within the housing, a piston rod, a dose selecting member to select the dose of the medicinal product to be expelled, and a drive member to expel the selected dose of the medicinal product. The housing is formed unitary so that the dose selecting member and the drive member are moveably retained within the housing. The injector may include a ratchet associated with an insert to ensure the piston rod only rotates in a single direction through the insert, a button located on the drive sleeve, and a clutch which upon depression of the button prevents rotation between the dose dial sleeve and the drive sleeve.Type: GrantFiled: February 11, 2011Date of Patent: November 18, 2014Assignee: DCA International Ltd.Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
-
Patent number: 8882721Abstract: A drive assembly for use in a drug delivery device is proposed, the drive assembly comprising: a housing having a proximal end and a distal end; an axis extending between the proximal end and the distal end; at least one drive member; a piston rod adapted to be driven along the axis by the drive member; an indicator adapted to provide positional information about a position of the piston rod relative to the proximal end, wherein the indicator and the piston rod are configured to convert a movement of the piston rod with respect to the housing into a rotational movement of the indicator. Additionally, a drug delivery device comprising the drive assembly is provided for.Type: GrantFiled: May 9, 2009Date of Patent: November 11, 2014Assignee: Sanofi-Aventis Deutschland GmbHInventors: Matthew Meredith Jones, David Aubrey Plumptre
-
Patent number: 8882720Abstract: The skin formulation dispenser includes a housing and a reservoir positioned within the housing containing a skin formulation. The dispenser includes an outlet nozzle from which the skin formulation exits and a pump assembly connecting the reservoir to the nozzle. An actuator is provided by which a user can mechanically apply pressure to the pump assembly to move the formulation from the reservoir to the nozzle. The nozzle extends from an end portion of the dispenser into a mating opening in an infuser portion of the applicator in such a manner to insure that the dispenser is authorized for use in the applicator, wherein the nozzle is configured so as to permit movement of the formulation by reasonable force from the reservoir through the nozzle while also preventing overly rapid evaporation of the formulation exiting from the nozzle.Type: GrantFiled: October 1, 2009Date of Patent: November 11, 2014Assignee: L'OrealInventors: Richard A. Reishus, Kenneth A. Pilcher
-
Patent number: 8882722Abstract: A lockout feature for an injection device includes a time lock that prevents a user from administering a dose of medicament prior to a pre-determined time interval. The lockout feature can interface with a cap and dose setting module to prevent removal of the cap or it can work to disable the dose delivery module to prevent an injection from occurring.Type: GrantFiled: October 8, 2010Date of Patent: November 11, 2014Assignee: Sanofi-Aventis Deutschland GmbHInventors: Andreas Bode, Paul Edward Jansen
-
Patent number: 8876766Abstract: A medicament delivery device includes a housing with a circle-segment-shaped compartment for a drive unit that moves at least one stopper in a medicament container and that includes a support wheel and central hub on which first and second parallel disks are fixedly attached and interconnected by an abutment cross-wall; spherical members between the abutment wall and adjacent the stopper; a clock spring within the hub with an outer end connected to the hub and an inner end connected to a one-direction-rotatable tubular hub coaxially arranged around a shaft fixedly attached to a housing part; and an activation member connected to the first disk by a hold-and-release mechanism. When the activation member is not depressed, the wheel and spring are held in a tensioned static state, and when the activation member is depressed, the spring and wheel are released and the spherical members are forced against the stopper.Type: GrantFiled: November 30, 2010Date of Patent: November 4, 2014Assignee: SHL Group ABInventors: Anders Holmqvist, Magnus Gustafsson, Stephan Lööf, Jochen Ratjen
-
Patent number: 8876782Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.Type: GrantFiled: November 2, 2012Date of Patent: November 4, 2014Assignee: DCA Design International Ltd.Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
-
Patent number: 8870830Abstract: An administration device for the administration of a liquid drug in adjustable doses may comprise an injection unit and an electronic indication unit. The injection unit may comprise a dosing mechanism and a manually operated dose setting component. The manually operated dose setting component may adjust the dosing mechanism to administer an administration dose amount of the liquid drug. The electronic indication unit may indicate a relationship between the administration dose amount and a target dose amount. A method for setting a dose of a liquid drug for administration may comprise providing an administration device, operating a manually operated dose setting component of the administration device, and continuing to operate the dose setting component until an electronic indication unit indicates that the administration dose amount is equal to the target dose amount.Type: GrantFiled: May 12, 2010Date of Patent: October 28, 2014Assignee: Roche Diagnostics International AGInventor: Axel Remde
-
Publication number: 20140316374Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.Type: ApplicationFiled: June 30, 2014Publication date: October 23, 2014Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
-
Patent number: 8864720Abstract: The invention relates to a dose setting mechanism (1) for a drug delivery device (2), comprising a number of separate dose setting elements (3.1 to 3.n), wherein a dose volume and/or a dose number are/is set by moving at least one of the respective dose setting elements (3.1 to 3.n) from a stack position (I) to an initial position (II), and wherein a medicament dose volume is applied by moving at least one dose setting element (3.1 to 3.n) from the initial position (II) to a dispense position (III) and wherein the movement of the dose setting element (3.1 to 3.n) from the initial position (II) to the dispense position (III) is limited by at least a height (h) of the dose setting elements (3.1 to 3.n) in the initial position (II), wherein each dose setting element (3.1 to 3.n) comprises a plurality of bulges (B1 to Bm) on at least one surface side (S1), wherein the height (h) of each dose setting element (3.1 to 3.n) equals a sum of the thickness (D) of the dose setting element (3.1 to 3.Type: GrantFiled: December 17, 2009Date of Patent: October 21, 2014Assignee: Sanofi-Aventis Deutschland GmbHInventors: Christopher James Smith, Timothy Giles Claughton