By Rotatable Means (e.g., Micrometer, Etc.) Patents (Class 604/211)
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Patent number: 11607500Abstract: A dose setting mechanism for a medicament delivery device, which dose setting mechanism comprises, a tubular member 10 having a longitudinal track 18 of a predetermined length; a dose drum 40, coaxial with the tubular member 10, and being axially and rotationally movable relative to the tubular member 10; a stop member 90, axially movable but rotationally locked relative to the tubular member 10, and further being in an axially slaved connection with the dose drum 40; wherein said stop member 90 comprises a track follower 98 in engagement with the longitudinal track 18, such that rotational movement of the dose drum 40 relative to the tubular member 10 may cause a maximum axial displacement of said dose drum 40 and said stop member 90, relative to the tubular member 10, corresponding to said predetermined length.Type: GrantFiled: November 21, 2019Date of Patent: March 21, 2023Assignee: SHL MEDICAL AGInventors: Anders Wieselblad, Thomas Bergens
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Patent number: 11559628Abstract: A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove and a helical spline. The inner housing helical spline guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.Type: GrantFiled: August 16, 2019Date of Patent: January 24, 2023Assignee: Sanofi-Aventis Deutschland GMBHInventor: David Plumptre
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Patent number: 11504475Abstract: Auto-injector for administering a dose of a liquid medicament includes a housing to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice to apply against an injection site. A spring means, upon activation, can push the needle from inside the housing through the orifice and past the proximal end, operate the syringe to supply the dose of medicament, and retract the syringe with the needle after delivering the medicament. An activating means can lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection.Type: GrantFiled: July 1, 2022Date of Patent: November 22, 2022Assignee: Sanofi-Aventis Deutschland GMBHInventors: Matthew Ekman, Yannick Hourmand, Timothy Donald Barrow-Williams
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Patent number: 11471606Abstract: A syringe is disclosed. The syringe comprises a plunger and a barrel. The plunger can be rotated relative to the barrel to lock, unlock and/or translate the components relative to each other.Type: GrantFiled: December 19, 2021Date of Patent: October 18, 2022Inventor: Robert Peliks
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Patent number: 11433186Abstract: Disclosed herein are delivery devices for delivering a volume of a drug product, placebo product, or other product including a fluid. The devices may include a barrel having a longitudinal axis, a proximal end region, and a distal end region. The proximal end region may include an opening, and the barrel may be configured to receive a drug therein. A plunger rod may be disposed at least partially inside the barrel and protruding from the opening. The plunger rod may include a rack having a plurality of teeth. The device may further include a pinion having a plurality of teeth configured to engage with the plurality of teeth of the rack, and rotation of the pinion against the rack may move at least a part of the plunger rod along the longitudinal axis of the barrel.Type: GrantFiled: March 31, 2021Date of Patent: September 6, 2022Assignee: REGENERON PHARMACEUTICALS, INC.Inventor: Sibgat Ulla
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Patent number: 11426524Abstract: A dosing device for an injection device, the dosing device including an actuating element for adjusting and/or dispensing a dose from the injection device, a thrust element for generating a forward movement for discharging a dose and a coupling to which the actuating element and the thrust element are coupled such that a rotational movement of the actuating element is transmitted directly to the thrust element and an axial movement of the actuating element is different than an axial movement of the thrust element.Type: GrantFiled: July 3, 2019Date of Patent: August 30, 2022Assignee: Ypsomed AGInventors: Stefan Burren, Jürg Hirschel, Samuel Martinoia, Ulrich Moser, Markus Tschirren
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Patent number: 11376367Abstract: An assembly for a medication delivery device, wherein the assembly is configured to perform a dose setting operation, the assembly having a dose setting sleeve and a drive sleeve, wherein the dose setting sleeve has a first dosing track having a first length and defining a first size of a dose and a second dosing track having a second length and defining a second size of a dose, wherein the first length is different from the second length and the first size is different from the second size. The drive sleeve has an engagement feature configured to engage with one of the dosing tracks. The assembly is configured such the dose setting operation has a first step wherein the engagement feature is aligned with one of the dosing tracks and a second step wherein the engagement feature is moved along the dosing track.Type: GrantFiled: January 25, 2018Date of Patent: July 5, 2022Assignee: NORTON HEALTHCARE LIMITEDInventors: Christopher James Smith, Dale Marc Comley, Lee Thomas Smith
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Patent number: 11357923Abstract: A sensing system for determining a zero position of a medication delivery device. The sensing system includes at least one actuator member, a biasing member, a stop surface and a sensor. The stop surface is structured and arranged within the device housing for abutment by a push surface of the at least one actuator member as a screw element of the device screws to a zero position from a dosing position. The abutment forces the at least one actuator member to move relative to the screw element from a first position to a second position against a resistance provided by the biasing member. A sensor within an electronics module is adapted to recognize the at least one actuator member at the second position.Type: GrantFiled: October 6, 2016Date of Patent: June 14, 2022Assignee: Eli Lilly and CompanyInventor: Gabriele Ganzitti
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Patent number: 11110227Abstract: An injecting device includes a housing having a longitudinal axis extending. A dose setting member is rotatable in the housing in a first or second direction about the longitudinal axis. A plunger extends through a bore of the dose setting member and into a bore of a barrel engaged with the housing. Pushing on an arm extending through a slot in the housing rotates the dose setting member in the first direction. As it rotates, indicia on the dose setting member are progressively displayed through an aperture in the housing. An actuator is engaged to release the dose setting member to rotate in the second direction and this rotation causes the plunger to move axially within the barrel's bore and push the pre-set dose of fluid therefrom. The dose setting member remains in a constant axial position within the housing during rotation in each of the first and second directions.Type: GrantFiled: April 17, 2019Date of Patent: September 7, 2021Inventors: Cheryl Muise, David Snaith, Steve A. Copeland, Mitchell Thompson
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Patent number: 10987471Abstract: An injection device having a drive member with first and second gear patterns that are fixed relative to each other. The drive member is rotatable and translatable in first and second opposing axial directions. A plunger expels medicament from a cartridge when it is translated in an advancing direction. A dosage indicator indicates a set dosage. A first gearing arrangement operably couples the first gear pattern with the plunger wherein rotation of the drive member in a first direction translates the drive member in a first axial direction without movement of the plunger and translation of the drive member in the opposite axial direction drives the plunger in the advancing direction. A second gearing arrangement operably couples the second gear pattern with the dosage indicator and moves the dosage indicator to indicate an increase in the set dosage when the drive member is translated in the first axial direction.Type: GrantFiled: May 12, 2016Date of Patent: April 27, 2021Assignee: Eli Lilly and CompanyInventor: Scott Matthew Stiffler
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Patent number: 10967128Abstract: The present disclosure relates to an administration mechanism for a medicament delivery device having a movable sleeve, and a delivery member cover having a distal end portion configured to receive the movable sleeve. The delivery member being configured to be linearly displaceable between a first position and a second position relative to the movable sleeve, wherein the distal end portion has an end face defining a guide surface and the movable sleeve has a radially outwards extending first follower structure configured to cooperate with the guide surface when the delivery member cover is moved from the first position towards the second position, causing the movable sleeve to rotate.Type: GrantFiled: June 27, 2017Date of Patent: April 6, 2021Assignee: SHL MEDICAL AGInventor: Anders Holmqvist
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Patent number: 10888889Abstract: The invention relates to a system having a dosing dispenser for dispensing pasty or viscous material with a housing, a cartridge displaceably accommodated therein and a walking piston accommodated in the cartridge that forms a unit ready for assembly with a shutter button to be arranged at a cartridge end.Type: GrantFiled: April 11, 2019Date of Patent: January 12, 2021Inventor: Gerhard Brugger
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Patent number: 10888669Abstract: A drug delivery device comprising a case adapted to hold a medicament container, a plunger disposed within the case and slidable from a proximal position into a distal position for delivering a medicament from the medicament container, an audible indicator that is arranged within a case pocket lateral to the plunger and that is in operative connection with the plunger, the audible indicator comprises at least one indicator spring and at least one locking element. The indicator spring is biased by the locking element, and the indicator spring relaxes due to a release of the locking element by a movement of the plunger.Type: GrantFiled: June 2, 2016Date of Patent: January 12, 2021Assignee: Sanofi-Aventis Deutschland GMBHInventors: Carsten Mosebach, Thomas Mark Kemp
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Patent number: 10881806Abstract: A drive mechanism for an injection device for setting and dispensing of a dose of a medicament includes an inner body fixable inside a housing of the injection device, the inner body including an elongated shaft extending in an axial direction. The elongated shaft includes an outer thread and a blocking structure on an outer circumference. The drive mechanism includes a tubular-shaped display member having an inner thread engaged with the outer thread of the inner body, a dose member axially displaceable between a dose setting position and a dose dispensing position relative to the inner body, and a blocking sleeve axially fixed to the dose member, rotationally fixed to the display member and including at least one blocking element to axially engage with the blocking structure to block an axial displacement of the dose member from the dose setting position towards the dose dispensing position.Type: GrantFiled: December 5, 2016Date of Patent: January 5, 2021Assignee: Sanofi-Aventis Deutschland GMBHInventors: James Alexander Senior, Elliot Baxter
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Patent number: 10864067Abstract: Bodily fluid collection systems are described where the system may be used for collecting and transferring sperm into a syringe. The syringe is configured to have a distal collection tip which is gently tapered or radiused to present a smooth and atraumatic surface and which is specifically configured and shaped to be inserted within and received by the collection receptacle. The distal collection tip has a shape which corresponds directly to a tapered reservoir defined at the bottom of the collection receptacle such that a distal opening defined through the tip is optimally positioned within the concentrated bodily fluid pooled within the reservoir for collection. Moreover, the gentle taper of the collection tip may present an atraumatic surface for inhibiting damage to the sperm contained within the ejaculate as the sperm is suctioned into the distal opening for insemination into the female.Type: GrantFiled: November 14, 2017Date of Patent: December 15, 2020Inventor: Sunny Jun
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Patent number: 10799647Abstract: The invention relates to an autoinjector for dispensing a liquid product, in particular a highly viscous medication, comprising: a housing, a product container, which is arranged in the housing and has a slidable piston, wherein the piston can be slid in a dispensing direction in order to dispense the product contained in the product container, a forward drive element, which acts on the piston as the product is being dispensed, a first spring, which is preloaded such that the product can be dispensed from the product container by the sliding of the forward drive element and the piston, and a rotation element, which is operatively coupled to the forward drive element, wherein the first spring acts on the rotation element in such a way that the rotation element is set into rotation in order to dispense the product, wherein the rotation element or the forward drive element has a thread having a variable pitch.Type: GrantFiled: December 21, 2017Date of Patent: October 13, 2020Assignee: Ypsomed AGInventors: Patrick Hostettler, Markus Tschirren
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Patent number: 10744266Abstract: A syringe comprising: a body delimiting a chamber; a piston able to slide in the chamber of the body along a longitudinal axis of the syringe, wherein the piston comprises a rod, a head, and a finger rest, which are all in one piece; and a deformable retention device designed to prevent the piston from leaving the body entirely, wherein the retention device is force-fitted in the chamber, extends around the piston over an angular sector strictly greater than 180° when it is in the assembled position, and has protruding external ribs which extend parallel to the longitudinal axis and are plastically deformable when the retention device is assembled in the chamber.Type: GrantFiled: July 8, 2016Date of Patent: August 18, 2020Assignee: GUERBETInventor: Jérôme Caclin
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Patent number: 10702660Abstract: An assembly includes a clutch member and a drive member movable relative to one another between a first relative position and a second relative position, in the first relative position, the clutch member and/or the drive member is rotatable relative to a housing, in the second relative position, the deflectable feature is arranged to prevent rotation of the clutch member and/or of the drive member relative to the housing, and wherein the deflectable feature and the interaction feature are arranged such that, when the clutch member and the drive member are moved relative to one another from the first relative position into the second relative position, the deflectable feature and the interaction feature mechanically interact in order to deflect the deflectable feature.Type: GrantFiled: January 19, 2016Date of Patent: July 7, 2020Assignee: Sanofi-Aventis Deutschland GMBHInventor: Andreas Bode
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Patent number: 10610649Abstract: A dispensing mechanism for delivering a dosage of medicament including a housing, a push button, a crank arm that is slideably engageable with the push button, a ram, and a ratchet gear releasably engageable with the crank arm and ram, translation of the push button along an axis causing the crank arm to engage and rotate the ratchet gear which causes the ram to distally advance relative to the housing.Type: GrantFiled: July 14, 2017Date of Patent: April 7, 2020Assignee: ANTARES PHARMA, INC.Inventors: Patrick Madsen, Hans Pflaumer, Kevin Swanson
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Patent number: 10583258Abstract: The mechanism includes a body, a drive member movable in the body, a main spring that is loaded when a dose is set and is released for moving the drive member during a delivery of a dose, and a movable trigger inhibiting a movement of the drive member, a movement of the trigger releasing the main spring and the drive member. The trigger is moved from a start position to an end position relative to the body during a setting of a dose, the end position having a distance from the start position that increases as the dose set increases.Type: GrantFiled: September 3, 2014Date of Patent: March 10, 2020Assignee: SanofiInventor: Simon Lewis Bilton
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Patent number: 10456528Abstract: The drive mechanism comprises a lead screw and a lead screw nut, which are aligned with an axis. The lead screw has screw threads having the same pitch and being intertwined.Type: GrantFiled: August 11, 2016Date of Patent: October 29, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventor: David Aubrey Plumptre
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Patent number: 10434286Abstract: A PIVC includes a catheter adapter having a catheter that extends distally from the catheter adapter, and an introducer needle that inserts through the catheter. The introducer needle has a grip component at a proximal end of the introducer needle. The grip component extends outwardly and distally to form a winged grip adjacent the catheter adapter when the introducer needle is inserted within the catheter. The grip component can be rotatable within the catheter adapter to allow repositioning of the winged grip with respect to the catheter adapter.Type: GrantFiled: June 16, 2017Date of Patent: October 8, 2019Assignee: Becton, Dickinson and CompanyInventors: Jonathan Karl Burkholz, S. Ray Isaacson
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Patent number: 10357614Abstract: An injection pen (1) includes a housing (2), a lead screw (75), a dose set member (6), a setback member (17), and a rotatable driver (60). The lead screw (75) is axially moveable in the housing (2). The dose set member (6) is connected to the housing (2) for dose setting and dose correcting. The setback member (17) is operatively connected to the dose set member (6). The rotatable driver (60) is operatively connected to the setback member (17) and the lead screw (75). The driver (60) is prevented from rotating during dose setting and dose correcting, and the driver (60) rotates during an injection to axially move the lead screw (75).Type: GrantFiled: July 30, 2014Date of Patent: July 23, 2019Assignee: Becton, Dickinson and CompanyInventors: Richard Cronenberg, Michael V. Quinn
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Patent number: 10314979Abstract: An injection pen (1) includes a housing (2), a lead screw (75), a dose set member (6), a setback member (17), and a rotatable driver (60). The lead screw (75) is axially moveable in the housing (2). The dose set member (6) is connected to the housing (2) for dose setting and dose correcting. The setback member (17) is operatively connected to the dose set member (6). The rotatable driver (60) is operatively connected to the setback member (17) and the lead screw (75). The driver (60) is prevented from rotating during dose setting and dose correcting, and the driver (60) rotates during an injection to axially move the lead screw (75).Type: GrantFiled: July 30, 2014Date of Patent: June 11, 2019Assignee: Becton, Dickinson and CompanyInventors: Richard Cronenberg, Michael V. Quinn
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Patent number: 10314978Abstract: An assembly for a drug delivery device is provided, wherein the assembly comprises an actuator which is configured to perform a setting movement in order to set a dose and which is configured to perform a dispense movement in order to dispense a dose and a piston rod which is configured to be moved in a distal direction in order to dispense a dose, and a snap feature which is configured to snap into engagement with the piston rod. The snap feature may be configured to inhibit a dispense movement of the actuator and/or a setting movement of the actuator when a maximum amount of medication has been delivered.Type: GrantFiled: February 3, 2014Date of Patent: June 11, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Michael Jugl, Axel Teucher
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Patent number: 10307544Abstract: The disclosure is directed to a differential gear mechanism for a drug delivery device with a primary drug delivery assembly and a secondary drug delivery assembly, wherein the primary drug delivery assembly comprises a primary dose dial sleeve and wherein the secondary drug delivery assembly comprises a secondary drive sleeve. The disclosure is also directed to a respective drug delivery device.Type: GrantFiled: May 27, 2015Date of Patent: June 4, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Matthew Meredith Jones, Samuel Keir Steel, Neal Alexander Blundred, Joseph Butler, Robert Frederick Veasey, David Plumptre, Anthony Paul Morris
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Patent number: 10238807Abstract: The present invention relates to a drive mechanism which is suitable for an injection device, especially a pen type drug delivery device. The mechanism includes a housing, a dosing member which during dose setting, dose resetting and dose dispensing rotates relative to the housing between a zero dose position and a maximum dose position, and an insert that is rotationally constrained to the housing. The dosing member and the insert each include at least one abutment feature contacting each other when the dosing member reaches its zero dose position during dose dispensing, and an audible and/or tactile feedback is generated by the contact of the abutment features.Type: GrantFiled: September 3, 2014Date of Patent: March 26, 2019Assignee: SanofiInventors: David Aubrey Plumptre, Simon Lewis Bilton
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Patent number: 10159801Abstract: Assembly for a drug delivery device and drug delivery device An assembly for a drug delivery device (1) is described comprising an activation member (6A) adapted and arranged to be axially moved in a delivery direction for triggering a dose delivery operation of the assembly, a first interaction member (17) and a second interaction member (18) which are adapted and arranged to mechanically cooperate with one another during a dose delivery operation of the assembly and to be rotated with respect to one another during the dose delivery operation, wherein the assembly is configured such that movement of the activation member (6A) in the delivery direction brings the interaction members (17, 18) into mechanical contact for generating a friction between the interaction members (17, 18), wherein an amount of friction controls a relative rotational speed of the interaction members (17, 18) during a dose delivery operation. Furthermore, a drug delivery device comprising the assembly is described.Type: GrantFiled: December 18, 2014Date of Patent: December 25, 2018Assignee: Sanofi-Aventis Deutschland GMBHInventors: Michael Jugl, Axel Teucher, Marc Holtwick
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Patent number: 10080845Abstract: A drug delivery device adapted to receive a cartridge and comprising a housing, an expelling assembly with a threaded piston rod, a threaded nut and a drive element arranged in non-rotational engagement with the piston rod, a drive coupling actuatable between a resetting state in which the piston rod can be moved proximally, and an operational state in which the drive element can drive the piston rod distally, wherein the drive element and the threaded nut are not moved axially relative to the housing when the drive coupling is actuated.Type: GrantFiled: May 20, 2014Date of Patent: September 25, 2018Assignee: Novo Nordisk A/SInventor: Morten Soerensen
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Patent number: 10076610Abstract: A drive mechanism for a drug delivery device includes an elongated housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction. A drive sleeve is rotatably supported in the housing, operably releasable from the piston rod for setting of a dose, and operably engageable with the piston rod for dispensing of the dose. A dose limiting member is engaged with the drive sleeve and engaged with the piston rod in such a way that it is displaced in axial direction relative to the drive sleeve when the drive sleeve rotates relative to the piston rod during a dose setting procedure. At least one stop is configured to engage with the dose limiting member for limiting the axial displacement of the dose limiting member during the dose setting procedure and to impede further displacement of the drive sleeve relative to the piston rod.Type: GrantFiled: April 8, 2014Date of Patent: September 18, 2018Assignee: SanofiInventors: Stefan Bayer, Daniel Berning, Philippe Blank, Wolfgang Pelzer, Michael Pfoser, Björn Wilden
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Patent number: 10046115Abstract: An automatic injector includes a housing having a guide, a drive control mechanism, a transmission assembly, a motor, and an energy source. The housing may further include a cartridge cover. A drive control mechanism includes a drive screw, a cartridge carrier, a plunger carrier, and one or more control transfer instruments, such as a puck or cylinder. The drive screw interfaces and connects with the plunger carrier. The automatic injector is configured to accept a variety of syringes as cartridges for drug delivery. The cartridges may be ejected from the injector and safely disposed after use, making the injector a reusable automatic injector. The reusable automatic injector may further include one or more sensors, such as a cartridge sensor and a patient sensor.Type: GrantFiled: December 16, 2014Date of Patent: August 14, 2018Assignee: UNL Holdings LLCInventors: Kevin Bokelman, George M. Wohlhieter, Thomas F. McGee, Arthur G. Marlin, Stefanie A. Hurowitz, David R. Jansen, Ellen Ni Chathail
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Patent number: 10010679Abstract: A handheld injection device includes a housing and a dose indicator positioned within and axially constrained to the housing and rotatable with respect to the housing during dose setting and during dose dispensing. The dose indicator includes a flexible clicker arm which, only during dispense, is displaced in a first radial direction and, when the device reaches its minimum dose position, in a second, opposite radial direction.Type: GrantFiled: April 8, 2014Date of Patent: July 3, 2018Assignee: SanofiInventors: William Marsh, Anthony Paul Morris, Joseph Butler, Matthew Jones
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Patent number: 9950122Abstract: A drug delivery device, comprises a housing having a longitudinal axis; an axially moveable component that is moveable along the longitudinal axis between a dose dialing position and a dose delivery position when a user operates the device to deliver a dose of drug; an encoder sleeve; an encoder pattern provided on the encoder sleeve, the encoder pattern comprising relatively conductive portions and relatively non-conductive portions that together comprise coded information; a contact-supporting component; and plural electrical contacts provided on the contact-supporting component. The plural electrical contacts contact the encoder pattern when the dose delivery button is in the dose dialing position and wherein the device is configured to move the contact-supporting component relative to the encoder sleeve as the axially moveable component moves from the dose dialing position to the dose delivery position such as to move the electrical contacts into positions where they do not contact the encoder pattern.Type: GrantFiled: January 13, 2014Date of Patent: April 24, 2018Assignee: Sanofi-Aventis Deutschland GmbHInventors: David Richard Mercer, Paul Richard Draper, Anthony Paul Morris, Stephen Francis Gilmore, George Cave, Samuel Steel
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Patent number: 9907913Abstract: Flush syringe assemblies capable of creating pulsatile movement of the plunger rod as it moves in the distal direction within a syringe barrel, while preventing overpressurization of the cathether are provided. An exemplary flush syringe assembly includes a syringe barrel with a first pulsing element and a chamber with flush solution, a plunger rod with a stopper and a second pulsing element that interacts with the first pulsing element to provide an engagement force that causes pulsatile movement of the plunger rod and a thumb press slidably attached to the plunger rod with a pulse control element. The pulse control element is compressible to create a compression force that is greater than the engagement force of the first pulsing element and the second pulsing element.Type: GrantFiled: July 14, 2015Date of Patent: March 6, 2018Assignee: Becton, Dickinson and CompanyInventors: Anthony J. Kosinski, Girum Yemane Tekeste, Nichola Charles
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Patent number: 9901685Abstract: The present invention relates to an injection device for automatic spring driven injection of a liquid drug. The injection device has a dose setting mechanism by which doses of an individual size can be set by a user, and a mechanical dose size display for displaying the size of the set dose. The scale drum (20) is coupled to a rotatable dose dial button (10) which is axially retained in relation to the housing (2) and by which the individual doses can be set.Type: GrantFiled: January 17, 2013Date of Patent: February 27, 2018Assignee: Novo Nordisk A/SInventor: Simon M. Pedersen
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Patent number: 9827373Abstract: The present invention relates to a torsion spring based automatic injection device for apportioning set doses of a liquid drug and which injection device is provided with an End-of-Dose feedback mechanism providing a user with an audible signal once the set dose has been injected. During injection, the scale drum rotates back to its “zero” position under influence of the torsion spring. This rotation is halted shortly before reaching the “zero” position by stopping means. The scale drum is thereafter only allowed to continue rotation and thus reach the “zero” position once the torque applied to the scale drum by the torsion spring surpasses a threshold value.Type: GrantFiled: June 2, 2014Date of Patent: November 28, 2017Assignee: Novo Nordisk A/SInventors: Simon Roervig, Steffen Hansen
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Patent number: 9802003Abstract: A medication delivery device having a housing having a proximal and a distal end, a medication receptacle designed to be engaged with the distal end of the housing by engagement of a first engagement feature with a second engagement feature and a dosing mechanism. The dosing mechanism includes a piston rod which is rotatable and moveable in a distal direction for medication delivery and a drive device for moving the piston rod in the distal direction for medication delivery. The medication receptacle includes an actuation element that brings a guiding element in a guiding position. The guiding element guides the piston rod for medication delivery. The first engagement feature and the second engagement feature are moveable into engagement by a movement of the medication receptacle which ends in a rotational movement without axial movement of the medication receptacle with respect to the housing.Type: GrantFiled: October 9, 2013Date of Patent: October 31, 2017Assignee: Sanofi-Aventis Deutschland GmbHInventors: Michael Harms, Steffen Raab, Dominic George Webber, James Roberts Howarth, Tevor John Beckett, Geoffrey Philip Gray, John David Cross
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Patent number: 9737666Abstract: An assembly for a drug delivery device is disclosed. An example assembly includes a housing, a rotation member, a drive member, and at least one correction member. The rotation member is adapted to be rotated with respect to the housing in a first rotational direction for delivering a dose of a drug. The drive member is coupleable to the rotation member for delivering the dose. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in the first rotational direction due to mechanical interaction of the rotation member and the drive member. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member.Type: GrantFiled: November 1, 2010Date of Patent: August 22, 2017Assignee: Sanofi-Aventis Deutschland GmbHInventors: Philippe Nzike, Steffen Raab, Uwe Dasbach, Uwe Boeser, Ulrich Bruggemann, Brice Ulrich Tchouadje, Kevin Igor Youmbi Ngatchou
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Patent number: 9707354Abstract: A dispensing mechanism for delivering a dosage of medicament including a housing, a push button, a crank arm that is slideably engageable with the push button, a ram, and a ratchet gear releasably engageable with the crank arm and ram, translation of the push button along an axis causing the crank arm to engage and rotate the ratchet gear which causes the ram to distally advance relative to the housing.Type: GrantFiled: March 11, 2014Date of Patent: July 18, 2017Assignee: ANTARES PHARMA, INC.Inventors: Patrick Madsen, Hans Pflaumer, Kevin Swanson
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Patent number: 9629962Abstract: An assembly for a drug delivery device (1), and a drug delivery device, are proposed with a housing (13) having proximal and distal ends. A dose member (23) is displaceable proximally with respect to the housing for setting of a dose of a drug. A clutch member (28) is displaceable proximally with respect to the housing when setting the dose. A stop member (30) is configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, The clutch member, when in the clutch stop position, is prevented from further displacement proximally with respect to the housing, and the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member proximally with respect to the housing during setting of the dose.Type: GrantFiled: June 1, 2010Date of Patent: April 25, 2017Assignee: Sanofi-Aventis Deutschland GmbHInventors: Michael Strehl, Udo Leuschner, Norbert Besenhardt
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Patent number: 9623214Abstract: A trans-endoscopic hydraulic balloon dilation apparatus includes a fluid reservoir containing a hydraulic fluid. A shaft has a lumen in fluid communication with a leading end of the fluid reservoir. A balloon is mounted on the shaft and an opening in the shaft enables hydraulic fluid to flow through the opening into or from the balloon. A piston secured to a leading end of a piston rod is slideably positioned within a lumen of the fluid reservoir. A hub secured to a trailing end of the fluid reservoir is centrally apertured to accommodate the piston rod so that a trailing end of the piston rod is external to the fluid reservoir. Displacement of the piston rod in a trailing-to-leading direction causes expansion of the balloon. Displacement of the piston rod in a leading-to-trailing direction causes deflation of the balloon. The piston can be locked into any position.Type: GrantFiled: August 5, 2015Date of Patent: April 18, 2017Assignee: University of South FloridaInventor: James Stephen Barthel
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Patent number: 9566389Abstract: The invention describes a locking arrangement which is advantageously used in an injection device for administering a medicinal drug, such as insulin for example.Type: GrantFiled: July 17, 2013Date of Patent: February 14, 2017Assignee: TecPharma Licensing AGInventors: Jürg Hirschel, Ursina Streit
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Patent number: 9498576Abstract: A drive mechanism for a drug delivery device which can be switched between a normal operation state and a reset state comprises of a housing having a proximal end and a distal end, a rotation member which is adapted to rotate in a first direction and in a second direction with respect to the housing, a drive member, wherein in the normal operation state the rotation member is coupled with the drive member so that the drive member follows rotational movement of the rotation member in the second direction, a piston rod, wherein in the normal operation state the piston rod is displaced in a distal direction with respect to the housing when the drive member rotates in the second direction with respect to the housing, a stop member, wherein in the normal operation state the stop member is coupled with the drive member so that the stop member prevents rotational movement of the drive member with respect to the housing in the first direction, and a separation member for switching the operation state, the separationType: GrantFiled: June 9, 2011Date of Patent: November 22, 2016Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Steffen Raab, Christopher James Smith, Mark Philip Horlock, Stephen David Butler
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Patent number: 9358344Abstract: An injection device (100) including a body (108, 332) for containing and dispensing a medicament, the body (108, 332) having a plurality of dosage indicator windows (120, 124; 336, 340, 344) for indicating a desired dosage of medicament, and a dose set sleeve (192, 326, 352) rotatably connected with the body (108, 332) for setting the desired dosage, the dose set sleeve (192, 326, 352) having a plurality of dosage numbers (196, 348) disposed thereon. Upon rotating the dose set sleeve (192, 326, 352) to set the desired dosage, the dosage numbers (196, 348) are consecutively visible through alternating ones of the plurality of dosage indicator windows (120, 124; 336, 340, 344).Type: GrantFiled: May 19, 2011Date of Patent: June 7, 2016Assignee: Becton, Dickinson and CompanyInventor: Trivikrama Pala
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Patent number: 9352097Abstract: A spindle (242; 414; 542; 642) for driving a bung of a cartridge is provided. The spindle includes a generally circular shaft having an outer surface (560). The generally circular shaft extends from a distal end to a proximal end of said circular shaft. A first helical groove (219; 519; 619) is provided along a first portion of the outer surface. The first helical groove having a first pitch. A second helical groove (221; 521; 621) provided along a second portion of the outer surface of the generally circular shaft. The second helical groove overlapping the first helical groove. The second helical groove having a second pitch.Type: GrantFiled: May 28, 2010Date of Patent: May 31, 2016Assignee: Sanofi-Aventis Deutschland GmbHInventor: David Plumptre
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Patent number: 9320854Abstract: A dose setting mechanism for a drug delivery device is provided comprising first maximum dose stop features (1) on a first component part (2) of the drug delivery device and corresponding second maximum dose stop features (3) on a second component part (4) of the drug delivery device, with the first and second maximum dose stop features (1, 3) being designed to limit a relative movement between the first and second component parts (2, 4). To limit the maximum dose which can be chosen, a maximum dose limiting device (5, 10, 10?, 10?, 10??) is provided interposed on the first component part (2) between the first and second maximum dose stop features (1, 3).Type: GrantFiled: December 16, 2010Date of Patent: April 26, 2016Assignee: Sanofi-Aventis Deutschland GmbHInventor: Christopher James Smith
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Patent number: 9289560Abstract: A drive assembly for a drug delivery device, comprising a housing with a proximal end and a distal end, and a longitudinal axis (A) extending between the proximal end and the distal end, a rotation sleeve being rotatable relative to the housing, and a piston rod being axially moveable relative to the housing. The piston rod is in mechanical cooperation with the rotation sleeve to be rotatable and moveable in the distal direction relative to the housing when the rotation sleeve rotates in a first direction (D1) and to be stationary in axial direction relative to the housing when the rotation sleeve rotates in a second direction (D2) opposite to the first direction (D1).Type: GrantFiled: December 6, 2010Date of Patent: March 22, 2016Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Steffen Raab, Uwe Dasbach
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Patent number: 9220845Abstract: A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base.Type: GrantFiled: January 24, 2014Date of Patent: December 29, 2015Assignee: Eli Lilly and CompanyInventors: William Godwin Atterbury, Mark Gerard Diller, Shannon Marie-Lynn Hoste, Bobby Lee Walters, Steven Michael Madland
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Patent number: 9192727Abstract: An injection device having a housing, a dose setting member being operable to set a desired dose, a piston rod adapted to cooperate with a piston to cause a set dose to be expelled, and a mode locking member. The mode locking member is adapted to be in a first extreme position and in a second extreme position. When the mode locking member is in the first extreme position the piston rod is prevented from cooperating with the piston, and when the mode locking member is in the second extreme position the dose setting member is prevented from being operated to set a dose. The mode locking member is adapted to be in the first extreme position during dose setting and the second extreme position during injection of a set dose.Type: GrantFiled: May 3, 2007Date of Patent: November 24, 2015Assignee: Novo Nordisk A/SInventors: Claus Schmidt Møller, Bennie Peder Smiszek Pedersen, Bo Kvolsbjerg
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Patent number: RE48283Abstract: The present artificial insemination instrument may include a single use, hollow, elongate, metal pipette and a single disposable syringe that is not toxic to bovine sperm. The apparatus is used with any type of diluent that is not toxic to bovine sperm. In various embodiments, a technician may use non-sorted reduced sperm count semen straws from a bull stud, cut an unsorted semen straw into several pieces to use one piece at a time per cow, thaw one straw and mix the non-sorted semen with diluent, or use reduced sperm count semen straws filled with sex sorted semen by the manufacturer. A procedure is disclosed to use the artificial insemination instrument, reduced sperm count semen from any of the aforementioned sources, a non-toxic syringe, and a diluent to achieve conception rates at least as good as conventional prior art device and procedure conception rates.Type: GrantFiled: January 30, 2019Date of Patent: October 27, 2020Inventor: Brad Stroud