By Rotatable Means (e.g., Micrometer, Etc.) Patents (Class 604/211)
  • Patent number: 10314979
    Abstract: An injection pen (1) includes a housing (2), a lead screw (75), a dose set member (6), a setback member (17), and a rotatable driver (60). The lead screw (75) is axially moveable in the housing (2). The dose set member (6) is connected to the housing (2) for dose setting and dose correcting. The setback member (17) is operatively connected to the dose set member (6). The rotatable driver (60) is operatively connected to the setback member (17) and the lead screw (75). The driver (60) is prevented from rotating during dose setting and dose correcting, and the driver (60) rotates during an injection to axially move the lead screw (75).
    Type: Grant
    Filed: July 30, 2014
    Date of Patent: June 11, 2019
    Assignee: Becton, Dickinson and Company
    Inventors: Richard Cronenberg, Michael V. Quinn
  • Patent number: 10314978
    Abstract: An assembly for a drug delivery device is provided, wherein the assembly comprises an actuator which is configured to perform a setting movement in order to set a dose and which is configured to perform a dispense movement in order to dispense a dose and a piston rod which is configured to be moved in a distal direction in order to dispense a dose, and a snap feature which is configured to snap into engagement with the piston rod. The snap feature may be configured to inhibit a dispense movement of the actuator and/or a setting movement of the actuator when a maximum amount of medication has been delivered.
    Type: Grant
    Filed: February 3, 2014
    Date of Patent: June 11, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Jugl, Axel Teucher
  • Patent number: 10307544
    Abstract: The disclosure is directed to a differential gear mechanism for a drug delivery device with a primary drug delivery assembly and a secondary drug delivery assembly, wherein the primary drug delivery assembly comprises a primary dose dial sleeve and wherein the secondary drug delivery assembly comprises a secondary drive sleeve. The disclosure is also directed to a respective drug delivery device.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: June 4, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Matthew Meredith Jones, Samuel Keir Steel, Neal Alexander Blundred, Joseph Butler, Robert Frederick Veasey, David Plumptre, Anthony Paul Morris
  • Patent number: 10238807
    Abstract: The present invention relates to a drive mechanism which is suitable for an injection device, especially a pen type drug delivery device. The mechanism includes a housing, a dosing member which during dose setting, dose resetting and dose dispensing rotates relative to the housing between a zero dose position and a maximum dose position, and an insert that is rotationally constrained to the housing. The dosing member and the insert each include at least one abutment feature contacting each other when the dosing member reaches its zero dose position during dose dispensing, and an audible and/or tactile feedback is generated by the contact of the abutment features.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: March 26, 2019
    Assignee: Sanofi
    Inventors: David Aubrey Plumptre, Simon Lewis Bilton
  • Patent number: 10159801
    Abstract: Assembly for a drug delivery device and drug delivery device An assembly for a drug delivery device (1) is described comprising an activation member (6A) adapted and arranged to be axially moved in a delivery direction for triggering a dose delivery operation of the assembly, a first interaction member (17) and a second interaction member (18) which are adapted and arranged to mechanically cooperate with one another during a dose delivery operation of the assembly and to be rotated with respect to one another during the dose delivery operation, wherein the assembly is configured such that movement of the activation member (6A) in the delivery direction brings the interaction members (17, 18) into mechanical contact for generating a friction between the interaction members (17, 18), wherein an amount of friction controls a relative rotational speed of the interaction members (17, 18) during a dose delivery operation. Furthermore, a drug delivery device comprising the assembly is described.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: December 25, 2018
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Jugl, Axel Teucher, Marc Holtwick
  • Patent number: 10080845
    Abstract: A drug delivery device adapted to receive a cartridge and comprising a housing, an expelling assembly with a threaded piston rod, a threaded nut and a drive element arranged in non-rotational engagement with the piston rod, a drive coupling actuatable between a resetting state in which the piston rod can be moved proximally, and an operational state in which the drive element can drive the piston rod distally, wherein the drive element and the threaded nut are not moved axially relative to the housing when the drive coupling is actuated.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: September 25, 2018
    Assignee: Novo Nordisk A/S
    Inventor: Morten Soerensen
  • Patent number: 10076610
    Abstract: A drive mechanism for a drug delivery device includes an elongated housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction. A drive sleeve is rotatably supported in the housing, operably releasable from the piston rod for setting of a dose, and operably engageable with the piston rod for dispensing of the dose. A dose limiting member is engaged with the drive sleeve and engaged with the piston rod in such a way that it is displaced in axial direction relative to the drive sleeve when the drive sleeve rotates relative to the piston rod during a dose setting procedure. At least one stop is configured to engage with the dose limiting member for limiting the axial displacement of the dose limiting member during the dose setting procedure and to impede further displacement of the drive sleeve relative to the piston rod.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: September 18, 2018
    Assignee: Sanofi
    Inventors: Stefan Bayer, Daniel Berning, Philippe Blank, Wolfgang Pelzer, Michael Pfoser, Björn Wilden
  • Patent number: 10046115
    Abstract: An automatic injector includes a housing having a guide, a drive control mechanism, a transmission assembly, a motor, and an energy source. The housing may further include a cartridge cover. A drive control mechanism includes a drive screw, a cartridge carrier, a plunger carrier, and one or more control transfer instruments, such as a puck or cylinder. The drive screw interfaces and connects with the plunger carrier. The automatic injector is configured to accept a variety of syringes as cartridges for drug delivery. The cartridges may be ejected from the injector and safely disposed after use, making the injector a reusable automatic injector. The reusable automatic injector may further include one or more sensors, such as a cartridge sensor and a patient sensor.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: August 14, 2018
    Assignee: UNL Holdings LLC
    Inventors: Kevin Bokelman, George M. Wohlhieter, Thomas F. McGee, Arthur G. Marlin, Stefanie A. Hurowitz, David R. Jansen, Ellen Ni Chathail
  • Patent number: 10010679
    Abstract: A handheld injection device includes a housing and a dose indicator positioned within and axially constrained to the housing and rotatable with respect to the housing during dose setting and during dose dispensing. The dose indicator includes a flexible clicker arm which, only during dispense, is displaced in a first radial direction and, when the device reaches its minimum dose position, in a second, opposite radial direction.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: July 3, 2018
    Assignee: Sanofi
    Inventors: William Marsh, Anthony Paul Morris, Joseph Butler, Matthew Jones
  • Patent number: 9950122
    Abstract: A drug delivery device, comprises a housing having a longitudinal axis; an axially moveable component that is moveable along the longitudinal axis between a dose dialing position and a dose delivery position when a user operates the device to deliver a dose of drug; an encoder sleeve; an encoder pattern provided on the encoder sleeve, the encoder pattern comprising relatively conductive portions and relatively non-conductive portions that together comprise coded information; a contact-supporting component; and plural electrical contacts provided on the contact-supporting component. The plural electrical contacts contact the encoder pattern when the dose delivery button is in the dose dialing position and wherein the device is configured to move the contact-supporting component relative to the encoder sleeve as the axially moveable component moves from the dose dialing position to the dose delivery position such as to move the electrical contacts into positions where they do not contact the encoder pattern.
    Type: Grant
    Filed: January 13, 2014
    Date of Patent: April 24, 2018
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: David Richard Mercer, Paul Richard Draper, Anthony Paul Morris, Stephen Francis Gilmore, George Cave, Samuel Steel
  • Patent number: 9907913
    Abstract: Flush syringe assemblies capable of creating pulsatile movement of the plunger rod as it moves in the distal direction within a syringe barrel, while preventing overpressurization of the cathether are provided. An exemplary flush syringe assembly includes a syringe barrel with a first pulsing element and a chamber with flush solution, a plunger rod with a stopper and a second pulsing element that interacts with the first pulsing element to provide an engagement force that causes pulsatile movement of the plunger rod and a thumb press slidably attached to the plunger rod with a pulse control element. The pulse control element is compressible to create a compression force that is greater than the engagement force of the first pulsing element and the second pulsing element.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: March 6, 2018
    Assignee: Becton, Dickinson and Company
    Inventors: Anthony J. Kosinski, Girum Yemane Tekeste, Nichola Charles
  • Patent number: 9901685
    Abstract: The present invention relates to an injection device for automatic spring driven injection of a liquid drug. The injection device has a dose setting mechanism by which doses of an individual size can be set by a user, and a mechanical dose size display for displaying the size of the set dose. The scale drum (20) is coupled to a rotatable dose dial button (10) which is axially retained in relation to the housing (2) and by which the individual doses can be set.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: February 27, 2018
    Assignee: Novo Nordisk A/S
    Inventor: Simon M. Pedersen
  • Patent number: 9827373
    Abstract: The present invention relates to a torsion spring based automatic injection device for apportioning set doses of a liquid drug and which injection device is provided with an End-of-Dose feedback mechanism providing a user with an audible signal once the set dose has been injected. During injection, the scale drum rotates back to its “zero” position under influence of the torsion spring. This rotation is halted shortly before reaching the “zero” position by stopping means. The scale drum is thereafter only allowed to continue rotation and thus reach the “zero” position once the torque applied to the scale drum by the torsion spring surpasses a threshold value.
    Type: Grant
    Filed: June 2, 2014
    Date of Patent: November 28, 2017
    Assignee: Novo Nordisk A/S
    Inventors: Simon Roervig, Steffen Hansen
  • Patent number: 9802003
    Abstract: A medication delivery device having a housing having a proximal and a distal end, a medication receptacle designed to be engaged with the distal end of the housing by engagement of a first engagement feature with a second engagement feature and a dosing mechanism. The dosing mechanism includes a piston rod which is rotatable and moveable in a distal direction for medication delivery and a drive device for moving the piston rod in the distal direction for medication delivery. The medication receptacle includes an actuation element that brings a guiding element in a guiding position. The guiding element guides the piston rod for medication delivery. The first engagement feature and the second engagement feature are moveable into engagement by a movement of the medication receptacle which ends in a rotational movement without axial movement of the medication receptacle with respect to the housing.
    Type: Grant
    Filed: October 9, 2013
    Date of Patent: October 31, 2017
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Harms, Steffen Raab, Dominic George Webber, James Roberts Howarth, Tevor John Beckett, Geoffrey Philip Gray, John David Cross
  • Patent number: 9737666
    Abstract: An assembly for a drug delivery device is disclosed. An example assembly includes a housing, a rotation member, a drive member, and at least one correction member. The rotation member is adapted to be rotated with respect to the housing in a first rotational direction for delivering a dose of a drug. The drive member is coupleable to the rotation member for delivering the dose. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in the first rotational direction due to mechanical interaction of the rotation member and the drive member. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: August 22, 2017
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Philippe Nzike, Steffen Raab, Uwe Dasbach, Uwe Boeser, Ulrich Bruggemann, Brice Ulrich Tchouadje, Kevin Igor Youmbi Ngatchou
  • Patent number: 9707354
    Abstract: A dispensing mechanism for delivering a dosage of medicament including a housing, a push button, a crank arm that is slideably engageable with the push button, a ram, and a ratchet gear releasably engageable with the crank arm and ram, translation of the push button along an axis causing the crank arm to engage and rotate the ratchet gear which causes the ram to distally advance relative to the housing.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: July 18, 2017
    Assignee: ANTARES PHARMA, INC.
    Inventors: Patrick Madsen, Hans Pflaumer, Kevin Swanson
  • Patent number: 9629962
    Abstract: An assembly for a drug delivery device (1), and a drug delivery device, are proposed with a housing (13) having proximal and distal ends. A dose member (23) is displaceable proximally with respect to the housing for setting of a dose of a drug. A clutch member (28) is displaceable proximally with respect to the housing when setting the dose. A stop member (30) is configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, The clutch member, when in the clutch stop position, is prevented from further displacement proximally with respect to the housing, and the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member proximally with respect to the housing during setting of the dose.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: April 25, 2017
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Strehl, Udo Leuschner, Norbert Besenhardt
  • Patent number: 9623214
    Abstract: A trans-endoscopic hydraulic balloon dilation apparatus includes a fluid reservoir containing a hydraulic fluid. A shaft has a lumen in fluid communication with a leading end of the fluid reservoir. A balloon is mounted on the shaft and an opening in the shaft enables hydraulic fluid to flow through the opening into or from the balloon. A piston secured to a leading end of a piston rod is slideably positioned within a lumen of the fluid reservoir. A hub secured to a trailing end of the fluid reservoir is centrally apertured to accommodate the piston rod so that a trailing end of the piston rod is external to the fluid reservoir. Displacement of the piston rod in a trailing-to-leading direction causes expansion of the balloon. Displacement of the piston rod in a leading-to-trailing direction causes deflation of the balloon. The piston can be locked into any position.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: April 18, 2017
    Assignee: University of South Florida
    Inventor: James Stephen Barthel
  • Patent number: 9566389
    Abstract: The invention describes a locking arrangement which is advantageously used in an injection device for administering a medicinal drug, such as insulin for example.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: February 14, 2017
    Assignee: TecPharma Licensing AG
    Inventors: Jürg Hirschel, Ursina Streit
  • Patent number: 9498576
    Abstract: A drive mechanism for a drug delivery device which can be switched between a normal operation state and a reset state comprises of a housing having a proximal end and a distal end, a rotation member which is adapted to rotate in a first direction and in a second direction with respect to the housing, a drive member, wherein in the normal operation state the rotation member is coupled with the drive member so that the drive member follows rotational movement of the rotation member in the second direction, a piston rod, wherein in the normal operation state the piston rod is displaced in a distal direction with respect to the housing when the drive member rotates in the second direction with respect to the housing, a stop member, wherein in the normal operation state the stop member is coupled with the drive member so that the stop member prevents rotational movement of the drive member with respect to the housing in the first direction, and a separation member for switching the operation state, the separation
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: November 22, 2016
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Steffen Raab, Christopher James Smith, Mark Philip Horlock, Stephen David Butler
  • Patent number: 9358344
    Abstract: An injection device (100) including a body (108, 332) for containing and dispensing a medicament, the body (108, 332) having a plurality of dosage indicator windows (120, 124; 336, 340, 344) for indicating a desired dosage of medicament, and a dose set sleeve (192, 326, 352) rotatably connected with the body (108, 332) for setting the desired dosage, the dose set sleeve (192, 326, 352) having a plurality of dosage numbers (196, 348) disposed thereon. Upon rotating the dose set sleeve (192, 326, 352) to set the desired dosage, the dosage numbers (196, 348) are consecutively visible through alternating ones of the plurality of dosage indicator windows (120, 124; 336, 340, 344).
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: June 7, 2016
    Assignee: Becton, Dickinson and Company
    Inventor: Trivikrama Pala
  • Patent number: 9352097
    Abstract: A spindle (242; 414; 542; 642) for driving a bung of a cartridge is provided. The spindle includes a generally circular shaft having an outer surface (560). The generally circular shaft extends from a distal end to a proximal end of said circular shaft. A first helical groove (219; 519; 619) is provided along a first portion of the outer surface. The first helical groove having a first pitch. A second helical groove (221; 521; 621) provided along a second portion of the outer surface of the generally circular shaft. The second helical groove overlapping the first helical groove. The second helical groove having a second pitch.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: May 31, 2016
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: David Plumptre
  • Patent number: 9320854
    Abstract: A dose setting mechanism for a drug delivery device is provided comprising first maximum dose stop features (1) on a first component part (2) of the drug delivery device and corresponding second maximum dose stop features (3) on a second component part (4) of the drug delivery device, with the first and second maximum dose stop features (1, 3) being designed to limit a relative movement between the first and second component parts (2, 4). To limit the maximum dose which can be chosen, a maximum dose limiting device (5, 10, 10?, 10?, 10??) is provided interposed on the first component part (2) between the first and second maximum dose stop features (1, 3).
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: April 26, 2016
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Christopher James Smith
  • Patent number: 9289560
    Abstract: A drive assembly for a drug delivery device, comprising a housing with a proximal end and a distal end, and a longitudinal axis (A) extending between the proximal end and the distal end, a rotation sleeve being rotatable relative to the housing, and a piston rod being axially moveable relative to the housing. The piston rod is in mechanical cooperation with the rotation sleeve to be rotatable and moveable in the distal direction relative to the housing when the rotation sleeve rotates in a first direction (D1) and to be stationary in axial direction relative to the housing when the rotation sleeve rotates in a second direction (D2) opposite to the first direction (D1).
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: March 22, 2016
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Steffen Raab, Uwe Dasbach
  • Patent number: 9220845
    Abstract: A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: December 29, 2015
    Assignee: Eli Lilly and Company
    Inventors: William Godwin Atterbury, Mark Gerard Diller, Shannon Marie-Lynn Hoste, Bobby Lee Walters, Steven Michael Madland
  • Patent number: 9192727
    Abstract: An injection device having a housing, a dose setting member being operable to set a desired dose, a piston rod adapted to cooperate with a piston to cause a set dose to be expelled, and a mode locking member. The mode locking member is adapted to be in a first extreme position and in a second extreme position. When the mode locking member is in the first extreme position the piston rod is prevented from cooperating with the piston, and when the mode locking member is in the second extreme position the dose setting member is prevented from being operated to set a dose. The mode locking member is adapted to be in the first extreme position during dose setting and the second extreme position during injection of a set dose.
    Type: Grant
    Filed: May 3, 2007
    Date of Patent: November 24, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Claus Schmidt Møller, Bennie Peder Smiszek Pedersen, Bo Kvolsbjerg
  • Patent number: 9149583
    Abstract: A method and system for proving a drug delivery device having a variable maximum dose. The drug delivery device comprising a first tubular member and a second tubular member rotatably coupled to the first tubular member. A maximum stop component is operatively coupled to the first tubular member and the second tubular member such that the maximum stop component is movable from a first position to a second position. The first position defines a first maximum dose that may be set by a user of said drug delivery device and the second position defines a second maximum dose that may be set by the user of said drug delivery device.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: October 6, 2015
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventor: David Plumptre
  • Patent number: 9144446
    Abstract: A bone filler mixing and delivery device includes a mixing section adapted to mix components to form bone filler. A syringe barrel is coupled to the mixing section and has an opening through which the bone filler can be dispensed. A controllable portal can be manipulated to open a flow path between the mixing section and the syringe barrel. A plunger assembly is adapted to extend telescopically in an axial direction through the syringe barrel to dispense the bone filler through the opening.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: September 29, 2015
    Assignee: GMEDELAWARE 2 LLC
    Inventors: Roy B. Bogert, James W. Nelson
  • Patent number: 9125993
    Abstract: A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove. The inner housing guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: September 8, 2015
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventor: David Plumptre
  • Patent number: 9126024
    Abstract: A trans-endoscopic hydraulic balloon dilation apparatus includes a fluid reservoir containing a hydraulic fluid. A shaft has a lumen in fluid communication with a leading end of the fluid reservoir. A balloon is mounted on the shaft and an opening in the shaft enables hydraulic fluid to flow through the opening into or from the balloon. A piston secured to a leading end of a piston rod is slideably positioned within a lumen of the fluid reservoir. A hub secured to a trailing end of the fluid reservoir is centrally apertured to accommodate the piston rod so that a trailing end of the piston rod is external to the fluid reservoir. Displacement of the piston rod in a trailing-to-leading direction causes expansion of the balloon. Displacement of the piston rod in a leading-to-trailing direction causes deflation of the balloon. The piston can be locked into any position.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: September 8, 2015
    Assignee: University of South Florida
    Inventor: James Stephen Barthel
  • Patent number: 9114212
    Abstract: The invention relates to an injection device (1, 100) configured to perform automatic priming upon removal of a protective cap (15, 115) from a cap receiving portion (9, 109) of a housing (2, 102). When mounted on the injection device (1, 100) the cap (15, 115) defines a first position for a drive member (10, 110) relative to the housing (2, 102), which drive member (10, 110) is capable of causing a piston rod (7, 107) to advance a piston (8, 108) in a reservoir (4, 104). Means (13, 120) are provided defining a second position for the drive member (10, 110) relative to the housing (2, 102). During removal of the cap (15, 115) from the cap receiving portion (9, 109) the drive member (10, 110) moves from the first position to the second position under the influence of a spring (11, 111), thereby causing the piston rod (7, 107) to pressurize the reservoir (4, 104).
    Type: Grant
    Filed: July 8, 2010
    Date of Patent: August 25, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Christian Peter Enggaard, Sara Niemann, Brian Ostergaard, Jacob Kollerup Jensen
  • Patent number: 9108001
    Abstract: The present invention relates to a drug delivery (5) comprising a housing (10) with a proximal end (30) and a distal end (22), a cartridge holder (14) adapted to retain a cartridge (16), the cartridge holder (14) comprising an at least partially transparent side wall (36), a piston rod (26), the piston rod (26) being adapted to drive a piston so as to engage the piston (28) into the cartridge (16), and a plurality of symbols (32) on the piston rod (26), the symbols (32) representing dosage information during operation of the drug delivery device (5) and being visible through a window aperture (40) in the housing (10) or in the cartridge holder (14). Furthermore, using a plurality of symbols (32) on a piston rod (26) to represent dosage information during operation of the drug delivery device (5) is disclosed.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: August 18, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: David Plumptre
  • Patent number: 9095660
    Abstract: A disposable double pointed injection needle has a needle hub to which a thin needle cannula is permanently fastened and which needle hub can be mounted on to a syringe comprising a dose setting and injection mechanism and a cartridge containing a liquid medicine to be injected subcutaneously into a human body. The needle hub is provided with a safety shield guided on the needle hub. The safety shield is urged in a direction away from the needle hub by a spring located between the needle hub and the safety shield. After injection the shield is moved away from the needle hub by the spring and locked in an irreversible position where the safety shield covers the needle cannula and prevents accidental needle stick injuries.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: August 4, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Carsten Gerner Larsen, Lars Stenholt, Anders Molin, Jorn Rex, Bjorn Gullak Larsen
  • Patent number: 9089651
    Abstract: A system for preventing delivery of less than a predetermined minimum dose of a medicament by providing a dose setting mechanism having a clutch ring rotationally fixed relative to the housing when a dose less than the minimum allowable dose is selected. The dose setting mechanism also includes a drug delivery device housing and a dose dial component positioned in the housing and rotatable during a dose setting step. A drive sleeve is positioned within the dose dial component, a spindle is positioned within the drive sleeve, and a clutch is positioned between the dose dial component and the drive sleeve. When the dose dial component is rotated to select a dose less than a minimum dose, a clutch ring prevents the drive sleeve from rotating to thereby prevent the selected dose from being administered.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: July 28, 2015
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Joseph Butler, David Plumptre
  • Patent number: 9057369
    Abstract: A device for administering a fluid product, the device including a first housing part provided with a receiver for the product, a second housing part detachably connectable to the first housing part, a piston rod held such that it can be displaced for the exertion of an emptying movement, an actuatable or releasable drive element for the piston rod, a coupling element including a coupling input element that couples the drive element to the piston rod in a coupling engagement, transmits a driving force of the drive element to the piston rod, and triggers the emptying movement, and a decoupling element displaceably connected to the second housing part and coupled to the first housing part such that it is displaced, by a movement of the housing parts in relation to each other when the housing parts are separated into a decoupling position wherein the piston rod is decoupled from the coupling input element.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: June 16, 2015
    Assignee: TecPharma Licensing AG
    Inventors: Philippe Kohlbrenner, Daniel Kuenzli, Christoph Meier, Peter Stettler, Juergen Wittmann, Martin Wittwer
  • Publication number: 20150141933
    Abstract: The invention relates to a injection device, comprising a housing being adapted to receive in its proximal housing portion a container with an injection fluid and to receive in its distal housing portion a dose setting and injection mechanism, wherein the mechanism includes a piston rod being axially displaceable with respect to the housing for dispensing injection fluid from the container, wherein the piston rod has an outer thread and is arranged torque proof with respect to the housing, dose setting means comprising a threaded element, which threaded element has an inner thread being in engagement with the outer thread of the piston rod, is designed so that its axial position relative to the housing is changeable and is rotatable relative to the piston rod and relative to the housing during setting of an injection dose, wherein the dose setting means are designed such that the threaded element is held in torque proof manner relative to the piston rod and to the housing during the injection of the beforehan
    Type: Application
    Filed: November 18, 2014
    Publication date: May 21, 2015
    Inventors: Michael Schabbach, Axel Roth, Gerhard Hambrecht
  • Patent number: 9028454
    Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: May 12, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
  • Patent number: 9022993
    Abstract: A drive assembly for a drug delivery device is presented having a housing with a proximal end and a distal end, a drive member, and a piston rod. A longitudinal axis extends between the proximal end and the distal end and the piston rod is axially moveable relative to the housing. The piston rod has a guide track and the drive member has a guide piece disposed and movable in the guide track. The guide track is configured with at least one section which is oblique relative to the longitudinal axis and defines a displacement for dispensing a single pre-set dose of medication during a relative movement between the guide piece and the piston rod when the guide piece cooperates with the oblique section between a distal final area of the oblique section and a proximal final area of the oblique section.
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: May 5, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Uwe Dasbach, Steffen Raab, Marianne Rottluff
  • Patent number: 9022991
    Abstract: An injection device for injection of set doses of medicine from a cartridge, in which syringe a dose is set by screwing a nut up along a threaded piston rod, whereby a dose setting drum, which carries on its cylindrical surface along a helix a scale of which a number corresponding to the set dose is shown in a window in the housing of the syringe, and an injection button, which is elevated over the end of the syringe, are moved axially a distance which is larger than the axial movement of the nut. A gear wheel gear transmission is established between the nut and the injection button.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: May 5, 2015
    Assignee: Novo Nordisk A/S
    Inventor: Claus Schmidt Moeller
  • Patent number: 9011390
    Abstract: Methods and devices for micro-dosing a liquid are disclosed herein. According to one embodiment, a method for a time controlled micro-dosing of a liquid from a liquid reservoir includes: receiving the liquid reservoir with a structure wherein the structure is portable; securing the liquid reservoir to the structure; connecting a second end of a drive unit to a piston disposed within the liquid reservoir; activating a drive motor; displacing the drive unit with respect to the structure towards the piston in an axial direction with the drive motor; moving the piston axially within the liquid reservoir; and micro-dosing the liquid from the liquid reservoir.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: April 21, 2015
    Assignee: Roche Diagnostics International AG
    Inventors: Roger Haenggi, Hanspeter Niklaus
  • Publication number: 20150100028
    Abstract: A medication dispensing device with a housing and a member wherein the member is moveable in a distal direction is useful in delivering medication to a patient. A fluid container can be used with the device and often has a moveable piston at one end and an outlet at the other. The member receives a force from a user and drives the piston in the distal direction to expel medication. An intermediate system is disposed between the member and the piston including a gear set that has a pinion in meshed engagement with a rack. The system allows the member to move a greater distance than the piston moves thereby increasing the force on the piston.
    Type: Application
    Filed: December 15, 2014
    Publication date: April 9, 2015
    Inventor: Claus Schmidt Moeller
  • Publication number: 20150100027
    Abstract: A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.
    Type: Application
    Filed: December 12, 2014
    Publication date: April 9, 2015
    Inventors: Janice L. COX, Matthew H. RUST, Thomas E. KRAMER, Peter A. HOEFT
  • Patent number: 8992487
    Abstract: An injection device for dispensing a product, the injection device including a moveable element which is moved for a dispensing operation, a spring, a product container holder and a product container, wherein the spring pushes against the moveable element to move the moveable element to an initial position after the dispensing operation has ended and against the product container to seat the product container in the product container holder.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: March 31, 2015
    Assignee: TecPharma Licensing, AG
    Inventors: Adrian Eich, Aurèle Horisberger, Patrick Hostettler, Malte Kladiwa, Stefan Meier, Peter Stettler, Jürgen Wittmann
  • Publication number: 20150088079
    Abstract: The drive mechanism for a drug delivery device comprises a piston rod, which is displaced in a distal direction for a delivery of a dose and in a proximal direction for a reset, and a resilient member, which acts on the piston rod during a reset and tends to restrict the movement of the piston rod in the proximal direction. The resilient member may be a biasing member provided for an automatic reset, a compression spring entering the piston rod or a torsion spring provided to generate a rotation. The drug delivery device is provided with such a drive mechanism.
    Type: Application
    Filed: May 28, 2013
    Publication date: March 26, 2015
    Inventors: Stephen David Butler, Mark Philip Horlock
  • Patent number: 8986261
    Abstract: A resettable drug delivery device includes a body, a cartridge holder for receiving a cartridge, and a releasable coupling connecting the cartridge holder to the body or the dose setting mechanism. During an initial rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a first axial direction relative to the body or the dose setting mechanism and during a continued rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a second, contrary axial direction.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: March 24, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: David Aubrey Plumptre, Christopher James Smith
  • Publication number: 20150080812
    Abstract: A mechanism for preventing setting of a dose, which exceeds the amount of a medicament in a reservoir in an injection device. The device can contain a threaded piston rod, a limiter and a driver. The three elements can be arranged such that during dose setting, the limiter is moved towards an end-of-content position, wherein dose setting is limited. The invention contains an accumulative and a non-accumulative embodiment. The invention further relates to a mechanism for preventing ejection of a dose exceeding the set dose.
    Type: Application
    Filed: November 21, 2014
    Publication date: March 19, 2015
    Inventors: Christian Peter Enggaard, Claus Schmidt Moller, Tom Hede Markussen
  • Patent number: 8968258
    Abstract: A resettable drive mechanism for a medication delivery device comprising a housing and a drive member rotatable in a second direction for delivering a dose. A piston rod driven distally when a drive member rotates in the second direction. A stop member prevents rotation of the drive member in a first direction opposite the second direction, when the stop member engages the drive member. A clutch member is movable between a delivery and reset position. When the clutch member is in the delivery position, the stop member and the drive member engage and the drive member is prevented from rotating in the first direction. When the clutch member is in the reset position, the drive member and the stop member disengage. The drive member is rotatable in the first direction.
    Type: Grant
    Filed: December 9, 2009
    Date of Patent: March 3, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Philippe Nzike, Steffen Raab, Ulrich Brüggemann, Uwe Dasbach, Uwe Boeser
  • Patent number: 8968256
    Abstract: A resettable drive mechanism for a medication delivery device comprising a housing, a drive member rotatable with respect to the housing in a second direction for delivering a dose of a medication, and a piston rod by the drive member, when drive member rotates in the second direction, a stop member adapted to prevent rotation of drive member in a first direction, when the stop member engages the drive member, a clutch member movable between a delivery position and a reset position. When clutch member is in the delivery position, stop member and drive member are engaged and drive member is prevented from rotation in the first direction, and when the clutch member is in the reset position, the drive member and the stop member are disengaged, the drive member is rotatable in the first direction.
    Type: Grant
    Filed: January 3, 2013
    Date of Patent: March 3, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Steffen Raab
  • Patent number: 8968255
    Abstract: An improved drug delivery device is provided having a piston rod that incorporates on its proximal end at least one guidepost that is configured for transmitting axial and rotational forces from a drive mechanism. The device comprises a drug delivery device housing and a medicament contained in the drug delivery device housing.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: March 3, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Philip Oakland
  • Patent number: 8968257
    Abstract: A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5?, 6, 6?) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27?, 28?) on the distal end of a cartridge assembly (20).
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: March 3, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Uwe Dasbach, Steffen Raab, Michael Harms, Udo Stauder, Volker Korger