By Rotatable Means (e.g., Micrometer, Etc.) Patents (Class 604/211)
  • Patent number: 9707354
    Abstract: A dispensing mechanism for delivering a dosage of medicament including a housing, a push button, a crank arm that is slideably engageable with the push button, a ram, and a ratchet gear releasably engageable with the crank arm and ram, translation of the push button along an axis causing the crank arm to engage and rotate the ratchet gear which causes the ram to distally advance relative to the housing.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: July 18, 2017
    Assignee: ANTARES PHARMA, INC.
    Inventors: Patrick Madsen, Hans Pflaumer, Kevin Swanson
  • Patent number: 9629962
    Abstract: An assembly for a drug delivery device (1), and a drug delivery device, are proposed with a housing (13) having proximal and distal ends. A dose member (23) is displaceable proximally with respect to the housing for setting of a dose of a drug. A clutch member (28) is displaceable proximally with respect to the housing when setting the dose. A stop member (30) is configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, The clutch member, when in the clutch stop position, is prevented from further displacement proximally with respect to the housing, and the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member proximally with respect to the housing during setting of the dose.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: April 25, 2017
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Strehl, Udo Leuschner, Norbert Besenhardt
  • Patent number: 9623214
    Abstract: A trans-endoscopic hydraulic balloon dilation apparatus includes a fluid reservoir containing a hydraulic fluid. A shaft has a lumen in fluid communication with a leading end of the fluid reservoir. A balloon is mounted on the shaft and an opening in the shaft enables hydraulic fluid to flow through the opening into or from the balloon. A piston secured to a leading end of a piston rod is slideably positioned within a lumen of the fluid reservoir. A hub secured to a trailing end of the fluid reservoir is centrally apertured to accommodate the piston rod so that a trailing end of the piston rod is external to the fluid reservoir. Displacement of the piston rod in a trailing-to-leading direction causes expansion of the balloon. Displacement of the piston rod in a leading-to-trailing direction causes deflation of the balloon. The piston can be locked into any position.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: April 18, 2017
    Assignee: University of South Florida
    Inventor: James Stephen Barthel
  • Patent number: 9566389
    Abstract: The invention describes a locking arrangement which is advantageously used in an injection device for administering a medicinal drug, such as insulin for example.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: February 14, 2017
    Assignee: TecPharma Licensing AG
    Inventors: Jürg Hirschel, Ursina Streit
  • Patent number: 9498576
    Abstract: A drive mechanism for a drug delivery device which can be switched between a normal operation state and a reset state comprises of a housing having a proximal end and a distal end, a rotation member which is adapted to rotate in a first direction and in a second direction with respect to the housing, a drive member, wherein in the normal operation state the rotation member is coupled with the drive member so that the drive member follows rotational movement of the rotation member in the second direction, a piston rod, wherein in the normal operation state the piston rod is displaced in a distal direction with respect to the housing when the drive member rotates in the second direction with respect to the housing, a stop member, wherein in the normal operation state the stop member is coupled with the drive member so that the stop member prevents rotational movement of the drive member with respect to the housing in the first direction, and a separation member for switching the operation state, the separation
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: November 22, 2016
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Steffen Raab, Christopher James Smith, Mark Philip Horlock, Stephen David Butler
  • Patent number: 9358344
    Abstract: An injection device (100) including a body (108, 332) for containing and dispensing a medicament, the body (108, 332) having a plurality of dosage indicator windows (120, 124; 336, 340, 344) for indicating a desired dosage of medicament, and a dose set sleeve (192, 326, 352) rotatably connected with the body (108, 332) for setting the desired dosage, the dose set sleeve (192, 326, 352) having a plurality of dosage numbers (196, 348) disposed thereon. Upon rotating the dose set sleeve (192, 326, 352) to set the desired dosage, the dosage numbers (196, 348) are consecutively visible through alternating ones of the plurality of dosage indicator windows (120, 124; 336, 340, 344).
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: June 7, 2016
    Assignee: Becton, Dickinson and Company
    Inventor: Trivikrama Pala
  • Patent number: 9352097
    Abstract: A spindle (242; 414; 542; 642) for driving a bung of a cartridge is provided. The spindle includes a generally circular shaft having an outer surface (560). The generally circular shaft extends from a distal end to a proximal end of said circular shaft. A first helical groove (219; 519; 619) is provided along a first portion of the outer surface. The first helical groove having a first pitch. A second helical groove (221; 521; 621) provided along a second portion of the outer surface of the generally circular shaft. The second helical groove overlapping the first helical groove. The second helical groove having a second pitch.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: May 31, 2016
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: David Plumptre
  • Patent number: 9320854
    Abstract: A dose setting mechanism for a drug delivery device is provided comprising first maximum dose stop features (1) on a first component part (2) of the drug delivery device and corresponding second maximum dose stop features (3) on a second component part (4) of the drug delivery device, with the first and second maximum dose stop features (1, 3) being designed to limit a relative movement between the first and second component parts (2, 4). To limit the maximum dose which can be chosen, a maximum dose limiting device (5, 10, 10?, 10?, 10??) is provided interposed on the first component part (2) between the first and second maximum dose stop features (1, 3).
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: April 26, 2016
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Christopher James Smith
  • Patent number: 9289560
    Abstract: A drive assembly for a drug delivery device, comprising a housing with a proximal end and a distal end, and a longitudinal axis (A) extending between the proximal end and the distal end, a rotation sleeve being rotatable relative to the housing, and a piston rod being axially moveable relative to the housing. The piston rod is in mechanical cooperation with the rotation sleeve to be rotatable and moveable in the distal direction relative to the housing when the rotation sleeve rotates in a first direction (D1) and to be stationary in axial direction relative to the housing when the rotation sleeve rotates in a second direction (D2) opposite to the first direction (D1).
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: March 22, 2016
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Steffen Raab, Uwe Dasbach
  • Patent number: 9220845
    Abstract: A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: December 29, 2015
    Assignee: Eli Lilly and Company
    Inventors: William Godwin Atterbury, Mark Gerard Diller, Shannon Marie-Lynn Hoste, Bobby Lee Walters, Steven Michael Madland
  • Patent number: 9192727
    Abstract: An injection device having a housing, a dose setting member being operable to set a desired dose, a piston rod adapted to cooperate with a piston to cause a set dose to be expelled, and a mode locking member. The mode locking member is adapted to be in a first extreme position and in a second extreme position. When the mode locking member is in the first extreme position the piston rod is prevented from cooperating with the piston, and when the mode locking member is in the second extreme position the dose setting member is prevented from being operated to set a dose. The mode locking member is adapted to be in the first extreme position during dose setting and the second extreme position during injection of a set dose.
    Type: Grant
    Filed: May 3, 2007
    Date of Patent: November 24, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Claus Schmidt Møller, Bennie Peder Smiszek Pedersen, Bo Kvolsbjerg
  • Patent number: 9149583
    Abstract: A method and system for proving a drug delivery device having a variable maximum dose. The drug delivery device comprising a first tubular member and a second tubular member rotatably coupled to the first tubular member. A maximum stop component is operatively coupled to the first tubular member and the second tubular member such that the maximum stop component is movable from a first position to a second position. The first position defines a first maximum dose that may be set by a user of said drug delivery device and the second position defines a second maximum dose that may be set by the user of said drug delivery device.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: October 6, 2015
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventor: David Plumptre
  • Patent number: 9144446
    Abstract: A bone filler mixing and delivery device includes a mixing section adapted to mix components to form bone filler. A syringe barrel is coupled to the mixing section and has an opening through which the bone filler can be dispensed. A controllable portal can be manipulated to open a flow path between the mixing section and the syringe barrel. A plunger assembly is adapted to extend telescopically in an axial direction through the syringe barrel to dispense the bone filler through the opening.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: September 29, 2015
    Assignee: GMEDELAWARE 2 LLC
    Inventors: Roy B. Bogert, James W. Nelson
  • Patent number: 9125993
    Abstract: A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove. The inner housing guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: September 8, 2015
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventor: David Plumptre
  • Patent number: 9126024
    Abstract: A trans-endoscopic hydraulic balloon dilation apparatus includes a fluid reservoir containing a hydraulic fluid. A shaft has a lumen in fluid communication with a leading end of the fluid reservoir. A balloon is mounted on the shaft and an opening in the shaft enables hydraulic fluid to flow through the opening into or from the balloon. A piston secured to a leading end of a piston rod is slideably positioned within a lumen of the fluid reservoir. A hub secured to a trailing end of the fluid reservoir is centrally apertured to accommodate the piston rod so that a trailing end of the piston rod is external to the fluid reservoir. Displacement of the piston rod in a trailing-to-leading direction causes expansion of the balloon. Displacement of the piston rod in a leading-to-trailing direction causes deflation of the balloon. The piston can be locked into any position.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: September 8, 2015
    Assignee: University of South Florida
    Inventor: James Stephen Barthel
  • Patent number: 9114212
    Abstract: The invention relates to an injection device (1, 100) configured to perform automatic priming upon removal of a protective cap (15, 115) from a cap receiving portion (9, 109) of a housing (2, 102). When mounted on the injection device (1, 100) the cap (15, 115) defines a first position for a drive member (10, 110) relative to the housing (2, 102), which drive member (10, 110) is capable of causing a piston rod (7, 107) to advance a piston (8, 108) in a reservoir (4, 104). Means (13, 120) are provided defining a second position for the drive member (10, 110) relative to the housing (2, 102). During removal of the cap (15, 115) from the cap receiving portion (9, 109) the drive member (10, 110) moves from the first position to the second position under the influence of a spring (11, 111), thereby causing the piston rod (7, 107) to pressurize the reservoir (4, 104).
    Type: Grant
    Filed: July 8, 2010
    Date of Patent: August 25, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Christian Peter Enggaard, Sara Niemann, Brian Ostergaard, Jacob Kollerup Jensen
  • Patent number: 9108001
    Abstract: The present invention relates to a drug delivery (5) comprising a housing (10) with a proximal end (30) and a distal end (22), a cartridge holder (14) adapted to retain a cartridge (16), the cartridge holder (14) comprising an at least partially transparent side wall (36), a piston rod (26), the piston rod (26) being adapted to drive a piston so as to engage the piston (28) into the cartridge (16), and a plurality of symbols (32) on the piston rod (26), the symbols (32) representing dosage information during operation of the drug delivery device (5) and being visible through a window aperture (40) in the housing (10) or in the cartridge holder (14). Furthermore, using a plurality of symbols (32) on a piston rod (26) to represent dosage information during operation of the drug delivery device (5) is disclosed.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: August 18, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: David Plumptre
  • Patent number: 9095660
    Abstract: A disposable double pointed injection needle has a needle hub to which a thin needle cannula is permanently fastened and which needle hub can be mounted on to a syringe comprising a dose setting and injection mechanism and a cartridge containing a liquid medicine to be injected subcutaneously into a human body. The needle hub is provided with a safety shield guided on the needle hub. The safety shield is urged in a direction away from the needle hub by a spring located between the needle hub and the safety shield. After injection the shield is moved away from the needle hub by the spring and locked in an irreversible position where the safety shield covers the needle cannula and prevents accidental needle stick injuries.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: August 4, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Carsten Gerner Larsen, Lars Stenholt, Anders Molin, Jorn Rex, Bjorn Gullak Larsen
  • Patent number: 9089651
    Abstract: A system for preventing delivery of less than a predetermined minimum dose of a medicament by providing a dose setting mechanism having a clutch ring rotationally fixed relative to the housing when a dose less than the minimum allowable dose is selected. The dose setting mechanism also includes a drug delivery device housing and a dose dial component positioned in the housing and rotatable during a dose setting step. A drive sleeve is positioned within the dose dial component, a spindle is positioned within the drive sleeve, and a clutch is positioned between the dose dial component and the drive sleeve. When the dose dial component is rotated to select a dose less than a minimum dose, a clutch ring prevents the drive sleeve from rotating to thereby prevent the selected dose from being administered.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: July 28, 2015
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Joseph Butler, David Plumptre
  • Patent number: 9057369
    Abstract: A device for administering a fluid product, the device including a first housing part provided with a receiver for the product, a second housing part detachably connectable to the first housing part, a piston rod held such that it can be displaced for the exertion of an emptying movement, an actuatable or releasable drive element for the piston rod, a coupling element including a coupling input element that couples the drive element to the piston rod in a coupling engagement, transmits a driving force of the drive element to the piston rod, and triggers the emptying movement, and a decoupling element displaceably connected to the second housing part and coupled to the first housing part such that it is displaced, by a movement of the housing parts in relation to each other when the housing parts are separated into a decoupling position wherein the piston rod is decoupled from the coupling input element.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: June 16, 2015
    Assignee: TecPharma Licensing AG
    Inventors: Philippe Kohlbrenner, Daniel Kuenzli, Christoph Meier, Peter Stettler, Juergen Wittmann, Martin Wittwer
  • Publication number: 20150141933
    Abstract: The invention relates to a injection device, comprising a housing being adapted to receive in its proximal housing portion a container with an injection fluid and to receive in its distal housing portion a dose setting and injection mechanism, wherein the mechanism includes a piston rod being axially displaceable with respect to the housing for dispensing injection fluid from the container, wherein the piston rod has an outer thread and is arranged torque proof with respect to the housing, dose setting means comprising a threaded element, which threaded element has an inner thread being in engagement with the outer thread of the piston rod, is designed so that its axial position relative to the housing is changeable and is rotatable relative to the piston rod and relative to the housing during setting of an injection dose, wherein the dose setting means are designed such that the threaded element is held in torque proof manner relative to the piston rod and to the housing during the injection of the beforehan
    Type: Application
    Filed: November 18, 2014
    Publication date: May 21, 2015
    Inventors: Michael Schabbach, Axel Roth, Gerhard Hambrecht
  • Patent number: 9028454
    Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: May 12, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
  • Patent number: 9022991
    Abstract: An injection device for injection of set doses of medicine from a cartridge, in which syringe a dose is set by screwing a nut up along a threaded piston rod, whereby a dose setting drum, which carries on its cylindrical surface along a helix a scale of which a number corresponding to the set dose is shown in a window in the housing of the syringe, and an injection button, which is elevated over the end of the syringe, are moved axially a distance which is larger than the axial movement of the nut. A gear wheel gear transmission is established between the nut and the injection button.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: May 5, 2015
    Assignee: Novo Nordisk A/S
    Inventor: Claus Schmidt Moeller
  • Patent number: 9022993
    Abstract: A drive assembly for a drug delivery device is presented having a housing with a proximal end and a distal end, a drive member, and a piston rod. A longitudinal axis extends between the proximal end and the distal end and the piston rod is axially moveable relative to the housing. The piston rod has a guide track and the drive member has a guide piece disposed and movable in the guide track. The guide track is configured with at least one section which is oblique relative to the longitudinal axis and defines a displacement for dispensing a single pre-set dose of medication during a relative movement between the guide piece and the piston rod when the guide piece cooperates with the oblique section between a distal final area of the oblique section and a proximal final area of the oblique section.
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: May 5, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Uwe Dasbach, Steffen Raab, Marianne Rottluff
  • Patent number: 9011390
    Abstract: Methods and devices for micro-dosing a liquid are disclosed herein. According to one embodiment, a method for a time controlled micro-dosing of a liquid from a liquid reservoir includes: receiving the liquid reservoir with a structure wherein the structure is portable; securing the liquid reservoir to the structure; connecting a second end of a drive unit to a piston disposed within the liquid reservoir; activating a drive motor; displacing the drive unit with respect to the structure towards the piston in an axial direction with the drive motor; moving the piston axially within the liquid reservoir; and micro-dosing the liquid from the liquid reservoir.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: April 21, 2015
    Assignee: Roche Diagnostics International AG
    Inventors: Roger Haenggi, Hanspeter Niklaus
  • Publication number: 20150100028
    Abstract: A medication dispensing device with a housing and a member wherein the member is moveable in a distal direction is useful in delivering medication to a patient. A fluid container can be used with the device and often has a moveable piston at one end and an outlet at the other. The member receives a force from a user and drives the piston in the distal direction to expel medication. An intermediate system is disposed between the member and the piston including a gear set that has a pinion in meshed engagement with a rack. The system allows the member to move a greater distance than the piston moves thereby increasing the force on the piston.
    Type: Application
    Filed: December 15, 2014
    Publication date: April 9, 2015
    Inventor: Claus Schmidt Moeller
  • Publication number: 20150100027
    Abstract: A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.
    Type: Application
    Filed: December 12, 2014
    Publication date: April 9, 2015
    Inventors: Janice L. COX, Matthew H. RUST, Thomas E. KRAMER, Peter A. HOEFT
  • Patent number: 8992487
    Abstract: An injection device for dispensing a product, the injection device including a moveable element which is moved for a dispensing operation, a spring, a product container holder and a product container, wherein the spring pushes against the moveable element to move the moveable element to an initial position after the dispensing operation has ended and against the product container to seat the product container in the product container holder.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: March 31, 2015
    Assignee: TecPharma Licensing, AG
    Inventors: Adrian Eich, Aurèle Horisberger, Patrick Hostettler, Malte Kladiwa, Stefan Meier, Peter Stettler, Jürgen Wittmann
  • Publication number: 20150088079
    Abstract: The drive mechanism for a drug delivery device comprises a piston rod, which is displaced in a distal direction for a delivery of a dose and in a proximal direction for a reset, and a resilient member, which acts on the piston rod during a reset and tends to restrict the movement of the piston rod in the proximal direction. The resilient member may be a biasing member provided for an automatic reset, a compression spring entering the piston rod or a torsion spring provided to generate a rotation. The drug delivery device is provided with such a drive mechanism.
    Type: Application
    Filed: May 28, 2013
    Publication date: March 26, 2015
    Inventors: Stephen David Butler, Mark Philip Horlock
  • Patent number: 8986261
    Abstract: A resettable drug delivery device includes a body, a cartridge holder for receiving a cartridge, and a releasable coupling connecting the cartridge holder to the body or the dose setting mechanism. During an initial rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a first axial direction relative to the body or the dose setting mechanism and during a continued rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a second, contrary axial direction.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: March 24, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: David Aubrey Plumptre, Christopher James Smith
  • Publication number: 20150080812
    Abstract: A mechanism for preventing setting of a dose, which exceeds the amount of a medicament in a reservoir in an injection device. The device can contain a threaded piston rod, a limiter and a driver. The three elements can be arranged such that during dose setting, the limiter is moved towards an end-of-content position, wherein dose setting is limited. The invention contains an accumulative and a non-accumulative embodiment. The invention further relates to a mechanism for preventing ejection of a dose exceeding the set dose.
    Type: Application
    Filed: November 21, 2014
    Publication date: March 19, 2015
    Inventors: Christian Peter Enggaard, Claus Schmidt Moller, Tom Hede Markussen
  • Patent number: 8968256
    Abstract: A resettable drive mechanism for a medication delivery device comprising a housing, a drive member rotatable with respect to the housing in a second direction for delivering a dose of a medication, and a piston rod by the drive member, when drive member rotates in the second direction, a stop member adapted to prevent rotation of drive member in a first direction, when the stop member engages the drive member, a clutch member movable between a delivery position and a reset position. When clutch member is in the delivery position, stop member and drive member are engaged and drive member is prevented from rotation in the first direction, and when the clutch member is in the reset position, the drive member and the stop member are disengaged, the drive member is rotatable in the first direction.
    Type: Grant
    Filed: January 3, 2013
    Date of Patent: March 3, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Steffen Raab
  • Patent number: 8968258
    Abstract: A resettable drive mechanism for a medication delivery device comprising a housing and a drive member rotatable in a second direction for delivering a dose. A piston rod driven distally when a drive member rotates in the second direction. A stop member prevents rotation of the drive member in a first direction opposite the second direction, when the stop member engages the drive member. A clutch member is movable between a delivery and reset position. When the clutch member is in the delivery position, the stop member and the drive member engage and the drive member is prevented from rotating in the first direction. When the clutch member is in the reset position, the drive member and the stop member disengage. The drive member is rotatable in the first direction.
    Type: Grant
    Filed: December 9, 2009
    Date of Patent: March 3, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Philippe Nzike, Steffen Raab, Ulrich Brüggemann, Uwe Dasbach, Uwe Boeser
  • Patent number: 8968255
    Abstract: An improved drug delivery device is provided having a piston rod that incorporates on its proximal end at least one guidepost that is configured for transmitting axial and rotational forces from a drive mechanism. The device comprises a drug delivery device housing and a medicament contained in the drug delivery device housing.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: March 3, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Philip Oakland
  • Patent number: 8968257
    Abstract: A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5?, 6, 6?) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27?, 28?) on the distal end of a cartridge assembly (20).
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: March 3, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Uwe Dasbach, Steffen Raab, Michael Harms, Udo Stauder, Volker Korger
  • Patent number: 8956331
    Abstract: A disposable auto injector (10) having a housing for accommodation of a syringe (18) with a needle movably positioned in the housing between a first position in which the needle is inside the housing and a second position in which the needle protrudes outside the housing, a driver (22) positioned laterally in relation to the syringe and configured for applying a force to the syringe thereby moving the syringe from the first position to the second position, a first injection lock configured in a locked state for preventing syringe movement from the first position to the second position and an injection trigger member (16) configured for releasing the first injection lock to an unlocked state wherein the first injection lock comprises a rotatable release shaft (34) configured for rotation between a first angular position in which it prevents movement of the syringe from the first position to the second position and a second angular position in which position does not prevent movement of the syringe from the fir
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: February 17, 2015
    Assignee: Bang & Olufsen Medicom A/S
    Inventors: Esben Weldingh Johansen, Jørn Winther Hald, Jørgen Rasmussen, Christian Maegaard
  • Publication number: 20150038917
    Abstract: An injection device with a travelling clutch which can be shifted between two different positions by the activation of an injection button. In the first position, the injection button and the driver is allowed to rotate relatively to the piston rod, which is blocked from rotation by the clicker element. In the second position, the drive sleeve and the injection button is axially movable while the piston rod is allowed to rotate.
    Type: Application
    Filed: October 16, 2014
    Publication date: February 5, 2015
    Inventor: Lars U. Nielsen
  • Publication number: 20150038916
    Abstract: The invention relates to a gearing mechanism for a dose delivery device wherein the dose can be set by rotating a dose setting member (2, 102), and by which the dose setting member (2, 102) and a push-button (4) elevates from one end of the device proportional to the set dose from a position fixed relative to a housing (1, 101), and by which an injection of the set dose can be clone by pressing the push-button back to its not elevated position, moving a piston rod (10, 110) cooperating with the piston in an cartridge (12, 112) and expelling a medicament out of the through a needle. The gearing mechanism is arranged in the device in such a way, that the loss of energy is very low.
    Type: Application
    Filed: October 16, 2014
    Publication date: February 5, 2015
    Inventor: Claus Schmidt Moller
  • Patent number: 8945069
    Abstract: An injection device (1) for administering a fixed dose of a medication is provided. The injection device (1) comprises a housing (2) wherein a drive mechanism comprising a drive member (3) is at least partially enclosed and a dosing element (34) which is fixed relative to the drive member (3). Here, a dose can be set by rotating the dosing element (34) relative to the housing (2) in a dose setting direction (s) and the dose can be dispensed by pushing the dosing element (34) towards the housing (2). Moreover, a method is provided for operating an injection device (1) for the administration of a fixed dose of a medication: A dose can be set by rotating a dosing element (34), a dose can be dispensed by pushing the dosing element (34) towards the housing (2) and a dose can be cancelled by rotating the dosing element (34) in a direction opposite to the dose setting direction (s).
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: February 3, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: David Plumptre, Christopher James Smith
  • Patent number: 8939945
    Abstract: A lead screw (5) with a screw thread (6) is arranged in a body (1) along an axis (4) and coupled to a lead screw nut (7) with a drive feature (8), so that the lead screw is helically rotatable in the lead screw nut. The lead screw and the lead screw nut are provided with stop features (9) interfering with a rotation of the lead screw in the lead screw nut when a force is applied to the lead screw in an axial direction. The lead screw nut has a surface area facing a guide feature (10) of the body. This surface area has a slope (12) varying around the axis. The assembly interacts such that the lead screw nut rotates in one rotational direction when a force is applied to the lead screw in the axial direction.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: January 27, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Robert Veasey, David Plumptre, Christopher Jones, Garen Kouyoumjian, Catherine Anne MacDonald
  • Publication number: 20150025475
    Abstract: A medical delivery system comprising a container and a coupling mechanism movable between a coupling position wherein distal movement of a drive mechanism is transferred to an actuator, and a non-coupling position wherein distal movement is not transferred to the actuator. Moreover the present invention relates to a dosing assembly for use in the medical delivery system and a container for use in the medical delivery system. Finally, the present invention relates to medical delivery system comprising a dosing assembly having means for preventing a drive stem of the dosing assembly from being moved in a distal direction.
    Type: Application
    Filed: April 23, 2014
    Publication date: January 22, 2015
    Applicant: NOVO NORDISK A/S
    Inventors: Asger V. Christiansen, Jonas Torry-Smith, Michael E. Hansen, Nikolaj E. Jakobsen, Ramin N. Elahi, Claus S. Moeller, Claus U. Gjoedesen
  • Patent number: 8936574
    Abstract: A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug delivery pump.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: January 20, 2015
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Christopher Wiegel, Marco DePolo, Steven Roe
  • Publication number: 20150018777
    Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.
    Type: Application
    Filed: October 1, 2014
    Publication date: January 15, 2015
    Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
  • Patent number: 8911411
    Abstract: An injection device with a travelling clutch which can be shifted between two different positions by the activation of an injection button. In the first position, the injection button and the driver is allowed to rotate relatively to the piston rod, which is blocked from rotation by the clicker element. In the second position, the drive sleeve and the injection button is axially movable while the piston rod is allowed to rotate.
    Type: Grant
    Filed: June 28, 2010
    Date of Patent: December 16, 2014
    Assignee: Novo Nordisk A/S
    Inventor: Lars Ulrik Nielsen
  • Patent number: 8900204
    Abstract: An injection device comprising: a base member (102); a plunger (104) for driving a piston in a distal direction; a driving member (106); and a gear mechanism (108) providing a gearing between the driving member (106) and the plunger (104) such that then the driving member (106) is moved at a first speed relative to the base member (102), the plunger (104) is moved at a second speed relative to the base member (102); wherein at least two of the base member (102), the plunger (104) and the driving member (106) are pivotally connected to the gear mechanism (108).
    Type: Grant
    Filed: June 20, 2012
    Date of Patent: December 2, 2014
    Assignee: Novo Nordisk A/S
    Inventor: Thomas Geertsen
  • Publication number: 20140350481
    Abstract: A drive mechanism for a medication delivery device is proposed, the drive mechanism comprising a housing having a proximal end and a distal end, a rotation member which is adapted to be rotated in a first direction with respect to the housing during setting of a dose of a medication and to be rotated in a second direction with respect to the housing during delivery of the dose, the second direction being opposite to the first direction, a piston rod which is adapted to be displaced in a distal direction with respect to the housing for delivering the dose, a drive member which follows rotational movement of the rotation member in the second direction during delivery of the dose, and a stop member which prevents rotational movement of the drive member with respect to the housing in the first direction during setting of the dose, wherein the rotational movement of the drive member in the second direction is converted into movement of the piston rod in the distal direction with respect to the housing.
    Type: Application
    Filed: August 14, 2014
    Publication date: November 27, 2014
    Inventors: Steffen Raab, Ulrich Bruggemann
  • Publication number: 20140343509
    Abstract: A dose setting mechanism for a medicament delivery device is presented having a pinion mounted to a locking member where the axis of rotation of the pinion is offset and parallel to the longitudinal axis of the housing containing the dose setting components. Primary and secondary dose members are engaged with the pinion to indicate a set dose of medicament.
    Type: Application
    Filed: August 1, 2014
    Publication date: November 20, 2014
    Inventors: Lucio Giambattista, Antonio Bendek
  • Publication number: 20140331996
    Abstract: The invention relates to a medicament delivery device comprising a locking mechanism (5) for locking a plunger rod (4). The locking mechanism (5) comprises a locking wheel (6) and locking means (7), said locking means (7) being moveable between an active position where the locking means (7) prevent the locking wheel (6) from rotation and an inactive position where the locking means (7) allow the locking wheel (6) to rotate, wherein said plunger rod (4) extends through an opening in the locking wheel (6); and a resilient member (8) arranged at the moveable locking means (7) and being arranged to act on the moveable locking means (7) to displace said movable looking means (7) towards the inactive position where the locking means (7) allow the locking wheel (6) to rotate.
    Type: Application
    Filed: November 28, 2012
    Publication date: November 13, 2014
    Applicant: SHL GROUP AB
    Inventor: Gunnar Elmén
  • Patent number: 8882722
    Abstract: A lockout feature for an injection device includes a time lock that prevents a user from administering a dose of medicament prior to a pre-determined time interval. The lockout feature can interface with a cap and dose setting module to prevent removal of the cap or it can work to disable the dose delivery module to prevent an injection from occurring.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: November 11, 2014
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Andreas Bode, Paul Edward Jansen
  • Patent number: 8882723
    Abstract: A drive member and a rotation member are rotatable with respect to a housing. A stop member is rotationally locked with the housing. Clutches unidirectionally rotationally engage the drive member with the rotation member and with the stop member when a unit is attached to the housing. A separating member is disposed between the rotation member and the stop member. The separating member causes a separation of the rotation member, the drive member and the stop member when the unit is removed. A coupling feature of the separating member is provided to engage the unit and to move the separating member when the unit is being attached to the housing or is being removed.
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: November 11, 2014
    Assignee: Sanofi-Aventis Deutchland GmbH
    Inventors: Christopher James Smith, Stephen David Butler, Mark Philip Horlock