By Rotatable Means (e.g., Micrometer, Etc.) Patents (Class 604/211)
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Publication number: 20130324937Abstract: A device for administering a product dose, the device including a display drum for displaying a product dose, a housing, a first conveying member moveable relative to the housing in a conveying direction, a second conveying member moveable relative to the housing in and counter to the conveying direction, the second conveying member in a first threaded engagement with the first conveying member while being rotationally movable relative to the housing and the first conveying member and being translationally movable relative to the first conveying member counter to the conveying direction, a metering apparatus by which a product dose can be adjusted and which encompasses the display drum, the display drum being rotationally movable relative to the housing while being translationally movable in and counter to the conveying direction in a second threaded engagement, and a coupling element which interconnects the first conveying member and the display drum in a torsion-resistant manner in a coupling engagement whiType: ApplicationFiled: August 2, 2013Publication date: December 5, 2013Applicant: TECPHARMA LICENSING AGInventor: Fritz Kirchhofer
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Publication number: 20130324936Abstract: A drive mechanism for a drug delivery device which can be switched between a normal operation mode and a reset mode comprises of a housing having a proximal end and a distal end, a piston rod which is adapted to be displaced in a distal direction with respect to the housing for delivering a dose in a normal operation mode of the drive mechanism, and which is adapted to be displaced in the proximal direction with respect to the housing in a reset mode of the drive mechanism, and a drive member which is rotationally moveable in a rotation direction with respect to the housing, wherein, in the normal operation mode, the drive member is coupled with the piston rod so that rotational movement of the drive member in the rotation direction with respect to the housing is converted into movement of the piston rod in the distal direction with respect to the housing, and wherein, in the reset mode, the piston rod is decoupled from the drive member.Type: ApplicationFiled: July 29, 2013Publication date: December 5, 2013Applicant: Sanofi-Aventis Deutschland GmbHInventors: Michael Heald, Stephen David Butler, Mark Philip Horlock
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Publication number: 20130310761Abstract: The drive mechanism comprises a lead screw (5) and a lead screw nut, which are aligned with an axis (4). The lead screw has screw threads (6, 16) having the same pitch and being intertwined.Type: ApplicationFiled: October 5, 2011Publication date: November 21, 2013Applicant: Sanofi-Aventis Deutschland GmbHInventor: David Aubrey Plumptre
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Patent number: 8585656Abstract: A method and system for priming a drug delivery device. The drug delivery device includes a dose dial sleeve and an internal housing portion. The dose dial sleeve is coupled to the internal housing. The dose dial sleeve rotates on a substantially circumferential rotational path during priming of the drug delivery device. Further, the dose dial sleeve rotates on a helical path during dose setting of the drug delivery device.Type: GrantFiled: May 27, 2010Date of Patent: November 19, 2013Assignee: Sanofi-Aventis Deutschland GmbHInventors: David Aubrey Plumptre, Christopher John Jones, Robert Frederick Veasey
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Patent number: 8579867Abstract: A medication delivery device comprising a housing, a medication receptacle, a piston rod which is moveable distally, and a drive device for rotating the piston rod in a first rotational direction. The piston rod comprises two threaded sections, a first threaded section for threaded engagement with a reset element and a second threaded section for threaded engagement with the drive device. In an operational state, the reset element is prevented from rotating and the piston rod prevented from moving proximally. In a resetting state, the reset element is allowed to rotate, such that the delivery device is resettable by rotating the piston rod and the reset element in a second rotational direction and moving the piston rod proximally.Type: GrantFiled: March 9, 2012Date of Patent: November 12, 2013Assignee: Sanofi-Aventis Deutschland GmbHInventors: Michael Harms, Steffen Raab, Dominic George Webber, James Robert Howarth, Trevor John Beckett, Geoffrey Philip Gray, John David Cross
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Patent number: 8579868Abstract: A medical delivery system (200) having a container (202) and a dosing assembly (204), where the container is fastenable to the dosing assembly by a movement comprising a translatory movement followed by a rotational movement. One of the container and the dosing assembly comprises one or more blocking elements (207) movable between a blocking position and a non-blocking position responsive to the rotational movement. Each blocking element is able to engage the other one of the container and the dosing assembly. A container suitable for use in said medical delivery system.Type: GrantFiled: July 15, 2007Date of Patent: November 12, 2013Assignee: Novo Nordisk A/SInventor: Asger Voss Christiansen
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Patent number: 8574198Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.Type: GrantFiled: October 25, 2011Date of Patent: November 5, 2013Assignee: DCA Design International Ltd.Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Patent number: 8574199Abstract: The present invention concerns a prefilled injection device having a container and a dose setting mechanism encapsulated inside the housing. The housing is made from two parts which are locked together by a bayonet coupling: In addition to the bayonet coupling, the two parts are also provided with irreversible locking means locking the two parts permanently together.Type: GrantFiled: June 7, 2007Date of Patent: November 5, 2013Assignee: Novo Nordisk A/SInventors: Martin von Bülow, Lars Ulrik Nielsen
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Patent number: 8568366Abstract: A reservoir module for an administering apparatus, the reservoir module including a rotational block which permits the rotational dosing movement in a first rotational direction and blocks the rotational dosing movement in a second rotational direction, wherein the rotational block includes at least one first rotational stopper and at least one second rotational stopper, the first rotational stopper and the second rotational stopper abut against one another in the end position of the dosage setting member, wherein the dosage setting member is moved away from the translational stopper by the permitted rotational dosing movement.Type: GrantFiled: May 22, 2007Date of Patent: October 29, 2013Assignee: TecPharma Licensing AGInventors: Fritz Kirchhofer, Michael Schaer
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Patent number: 8562544Abstract: A pen type device for ultrasound guided fine needle aspiration cytology and biopsy comprises a hollow body having a needle hole, a sliding part slidably mounted inside the body, elastic members mounted inside the body, a syringe having a cylinder mounted, a rotating part disposed inside the sliding part and the body, a head screw-coupled to the rear end of the sliding part and drawn out from the body, and a negative pressure generating part mounted on the body to generate negative pressure to the syringe by pulling a piston of the syringe when a button located on the outer face of the body is pushed.Type: GrantFiled: January 27, 2012Date of Patent: October 22, 2013Inventor: Hyuk Ho Kwon
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Publication number: 20130274681Abstract: A dose setting mechanism for a medicament delivery device is presented having a pinion mounted to a locking member where the axis of rotation of the pinion is offset and parallel to the longitudinal axis of the housing containing the dose setting components. Primary and secondary dose members are engaged with the pinion to indicate a set dose of medicament.Type: ApplicationFiled: May 17, 2013Publication date: October 17, 2013Inventors: Lucio Giambattista, Antonio Bendek
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Patent number: 8545456Abstract: An administering apparatus including a rotational block which, in the end position of the dosage setting member, permits the rotational dosing movement in a first rotational direction and blocks the rotational dosing movement in a second rotational direction, wherein the rotational block comprises at least one first rotational stopper and at least one second rotational stopper, the first rotational stopper and the second rotational stopper abutting against one another in the end position of the dosage setting member, wherein the at least one first rotational stopper is secured against rotating by the dosage setting member and the at least one second rotational stopper is secured against rotating by the casing.Type: GrantFiled: May 23, 2007Date of Patent: October 1, 2013Assignee: TecPharma Licensing AGInventors: Fritz Kirchhofer, Michael Schaer
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Publication number: 20130245558Abstract: The invention relates to a medicament delivery device comprising a housing arranged to receive a medicament container (20), a drive unit (25) arranged to act on a stopper (27) in said medicament container (20), which drive unit (25) comprises a torsion drive spring (50). A dose setting member (56) is operably connected to said drive unit (25) such that a manual turning of said dose setting member (56) causes a tensioning of said torsion drive spring (50). The device further comprises an activation mechanism (76) having an activation button (94) protruding through the distal end of the device, wherein said activation mechanism (76) is operably connected to said drive unit (25) such that actuation of said activation mechanism (76) causes a release of said drive unit (25) whereby a set dose of medicament is delivered.Type: ApplicationFiled: November 18, 2011Publication date: September 19, 2013Applicant: SHL Group ABInventor: Anders Holmqvist
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Patent number: 8529532Abstract: Described generally herein are tissue therapy devices, which may comprise a sealant layer and a suction apparatus. The sealant layer functions so as to create a sealed enclosure between it and the surface of a patient by forming, preferably, an airtight seal around an area of tissue that requires negative pressure therapy. The tissue therapy device may comprise a suction apparatus. The suction apparatus is typically in fluid communication with the sealant layer and functions so as to reduce the amount of pressure present underneath the sealant layer. The reduced pressure is self-created by the suction apparatus. Together the sealant layer and the suction apparatus preferably create a closed reduced pressure therapy system. Preferably, the pressure under the sealant layer is reduced by expanding the volume of the enclosure space and thereby decreasing the density of the air molecules under the sealant layer.Type: GrantFiled: September 26, 2011Date of Patent: September 10, 2013Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Moshe Pinto, Dean Hu, Kenton Fong
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Patent number: 8529513Abstract: A device for administering an injectable substance, the device including a housing, a translation member moveable in a translation direction, a rotation member rotatably moveable about a rotation axis and coupled to the translation member to support the translation member counter to the translation direction, a rotary bearing including a bearing body bearing the rotation member rotatably about the rotation axis, the rotary bearing having support surfaces for supporting the rotation member axially on the bearing body, and a device for reducing play whereby at least two support surfaces are brought into contact with a pressing force, thereby reducing an axial play of the rotary bearing.Type: GrantFiled: March 23, 2006Date of Patent: September 10, 2013Assignee: Roche Diagnostics International AGInventors: Daniel Peter, Simone Gafner-Geiser
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Patent number: 8517992Abstract: A drive mechanism for an injection device in which a piston is successively moved in a first axial direction in relation to a medicament cartridge containing a medicament selectively to drive a bung closing a first end of the medicament cartridge into the medicament cartridge to expel medicament through a delivery member located at a second end of the medicament cartridge, the drive mechanism comprising: a base member, a first drive member fixed relative to the base member, a second drive member axially and rotatably moveable relative to the first drive member and a piston member axially moveable relative to the first and second drive member, wherein the second drive member is drivingly connected between the first drive member and the piston member such that rotation of the second drive member in a first direction of rotation relative to the first drive member and the piston member causes the second drive member to move in the first axial direction relative to the first drive member and the piston member to mType: GrantFiled: July 14, 2010Date of Patent: August 27, 2013Assignee: Sanofi-Aventis Deutschland GmbHInventor: Christopher Jones
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Publication number: 20130218130Abstract: A method and system for priming a drug delivery device. The drug delivery device includes a dose dial sleeve and an internal housing portion. The dose dial sleeve is coupled to the internal housing. The dose dial sleeve rotates on a substantially circumferential rotational path during priming of the drug delivery device. Further, the dose dial sleeve rotates on a helical path during dose setting of the drug delivery device.Type: ApplicationFiled: March 20, 2013Publication date: August 22, 2013Inventor: Sanofi-Aventis Deutschland GmbH
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Publication number: 20130218096Abstract: A dose setting mechanism for a drug delivery device is provided comprising first maximum dose stop features (1) on a first component part (2) of the drug delivery device and corresponding second maximum dose stop features (3) on a second component part (4) of the drug delivery device, with the first and second maximum dose stop features (1, 3) being designed to limit a relative movement between the first and second component parts (2, 4). To limit the maximum dose which can be chosen, a maximum dose limiting device (5, 10, 10?, 10?, 10??) is provided interposed on the first component part (2) between the first and second maximum dose stop features (1, 3).Type: ApplicationFiled: December 16, 2010Publication date: August 22, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Christopher James Smith, Philip Oakland
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Patent number: 8512296Abstract: An injection device (30) features a housing (42, 52) for reception of a container (34) having a fluid (32) to be injected, a first element (94) for ejecting injection fluid (32) from such a container (34), and said first element (94) has an external thread (92). A metering element (66, 88) has an internal thread (90) that is in engagement with the external thread (92) of the first element (94), and said metering element (66) is rotatable, together with the first element (94), for preselection of a desired injection dose. A coupling arrangement (K1) serves, during an injection operation, to create a nonrotatable connection between the first element (94) and the housing (42, 52) and thereby to block, during an injection operation, a rotation of the first element (94) relative to the housing (42, 52) but to enable a rotation of the metering element (66, 88) relative to the housing (42, 52).Type: GrantFiled: November 5, 2007Date of Patent: August 20, 2013Assignee: Haselmeier GmbHInventors: Jochen Gabriel, Joachim Keitel
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Publication number: 20130204204Abstract: The drive mechanism comprises a drive member inside a housing, a rotation member and a dose member. The drive member is rotatable with respect to the housing. The rotation member is also rotatable and unidirectionally rotationally engaged with the drive member. The dose member is able to move along a set/deliver path between a first axial position and a second axial position in either direction or to move along a cancel path from the second axial position to the first axial position. An engagement of the dose member with the rotation member causes the rotation member to rotate when the dose member is moved along the set/deliver path. The drive member is not rotated when the dose member is moved along the cancel path. A button in/out spline can be provided for the set/deliver path and a cancel spline for the cancel path.Type: ApplicationFiled: June 9, 2011Publication date: August 8, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Stephen David Butler, Mark Philip Horlock
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Publication number: 20130204205Abstract: A drive assembly for a medication delivery device is provided which is switchable from an operational state to a resetting state and which comprises: a housing having a proximal end and a distal end, a drive member adapted to be rotated with respect to the housing, and a stop member adapted to prevent rotational movement of the drive member in a first direction with respect to the housing and to permit rotational movement of the drive member in a second direction with respect to the housing, the second direction being opposite to the first direction. In the operational state of the drive assembly the stop member is held in engagement with the drive member, and for switching into the resetting state of the drive assembly the stop member is enabled to disengage from the drive member caused by gravity due to the weight of the stop member.Type: ApplicationFiled: June 9, 2011Publication date: August 8, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: Mark Philip Horlock
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Publication number: 20130204193Abstract: A medicament delivery device has a housing for a medicament container; a dose setting member rotatable in relation to the housing; a plunger rod acting on a stopper inside the medicament container; a driver that converts rotation of the dose setting member into translation of the plunger rod; a transversal clock spring connected to the dose setting member and to a drive member connected to the plunger rod, such that rotating the dose setting member tensions the spring; a spring hold and release member releasably connected to the drive member; and an activator having a distal end protruding through a distal passage of the dose setting member and connected to the hold and release member. Pushing the activator proximally moves the hold and release member proximally, releasing the spring from its tensioned state and forcing the drive member to rotate.Type: ApplicationFiled: April 14, 2011Publication date: August 8, 2013Applicant: SHL GROUP ABInventor: Anders Holmqvist
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Patent number: 8500700Abstract: A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained.Type: GrantFiled: March 11, 2011Date of Patent: August 6, 2013Assignee: Roche Diagnostics International AGInventors: Ulrich Haueter, Martin Wyss, Florian Kuehni
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Patent number: 8500693Abstract: The present invention relates to a device for automatic injection of a product, comprising: a body (3) housing a container, the container being movable relative to said body between an initial position, to an insertion position; a safety shield (26) movable with respect to said container and said body between an insertion position to a protection position, when the user removes the device from an injection site; an external socket (48) receiving the body and provided with selection means (53) which can be placed by a user: either in a first position, in which the body (3) and the external socket (48) are bound to each other, the safety shield extending beyond the distal end of both said body and said external socket in the protection position; or in a second position, in which the external socket (48) is able to move axially in the distal direction with respect to the body (3), both the safety shield and the external socket extending beyond the distal end of said body, in the protection position.Type: GrantFiled: September 25, 2007Date of Patent: August 6, 2013Assignee: Becton Dickinson FranceInventor: Lionel Maritan
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Patent number: 8500701Abstract: A device for administering a product dose, the device including a display drum for displaying the product dose, a housing, a first conveying member moveable relative to the housing in a conveying direction, a second conveying member moveable relative to the housing in and counter to the conveying direction, the second conveying member in a first threaded engagement with the first conveying member while being rotationally movable relative to the housing and the first conveying member and being translationally movable relative to the first conveying member counter to the conveying direction, a metering apparatus by which the product dose can be adjusted and which encompasses the display drum, the display drum being rotationally movable relative to the housing while being translationally movable in and counter to the conveying direction in a second threaded engagement, and a coupling element which interconnects the first conveying member and the display drum in a torsion-resistant manner in a coupling engagementType: GrantFiled: August 22, 2007Date of Patent: August 6, 2013Assignee: TecPharma Licensing AGInventor: Fritz Kirchhofer
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Patent number: 8491538Abstract: An injection device including a drive unit, a delivery unit, a dosing unit, a trigger for triggering an injection, a first coupling mechanism between the drive unit and the delivery unit, and a second coupling mechanism between the dosing unit and the drive unit, wherein the drive unit is tensioned by a rotation of the dosing unit and when the drive unit is tensioned the first coupling mechanism is disengaged and the second coupling mechanism is engaged, and wherein when an injection is triggered first the first coupling mechanism is engaged and then the second coupling mechanism is disengaged. In some embodiments, the device may include a third coupling mechanism which only releases the delivery unit after the engagement and disengagement which follow a triggering.Type: GrantFiled: October 27, 2011Date of Patent: July 23, 2013Assignee: TecPharma Licensing AGInventors: Philippe Kohlbrenner, Peter Stettler, Patrick Hostettler, Juergen Wittmann, Martin Wittwer
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Publication number: 20130184653Abstract: The invention relates to a gearing mechanism for a dose delivery device wherein the dose can be set by rotating a dose setting member (2, 102), and by which the dose setting member (2, 102) and a push-button (4) elevates from one end of the device proportional to the set dose from a position fixed relative to a housing (1, 101), and by which an injection of the set dose can be done by pressing the push-button back to its not elevated position, moving a piston rod (10, 110) cooperating with the piston in an cartridge (12, 112) and expelling a medicament out of the through a needle. The gearing mechanism is arranged in the device in such a way, that the loss of energy is very low.Type: ApplicationFiled: September 23, 2011Publication date: July 18, 2013Applicant: ELI LILLY AND COMPANYInventor: Claus Schmidt Møller
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Publication number: 20130184652Abstract: A drive member and a rotation member are rotatable with respect to a housing. A stop member is rotationally locked with the housing. Clutches unidirectionally rotationally engage the drive member with the rotation member and with the stop member when a unit is attached to the housing. A separating member is disposed between the rotation member and the stop member. The separating member causes a separation of the rotation member, the drive member and the stop member when the unit is removed. A coupling feature of the separating member is provided to engage the unit and to move the separating member when the unit is being attached to the housing or is being removed.Type: ApplicationFiled: June 9, 2011Publication date: July 18, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Christopher James Smith, Stephen David Butler, Mark Philip Horlock
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Patent number: 8486007Abstract: A pen injection device designed for use with dual or multi-chamber cartridges 14, is provided with an extended length plunger 24 having a non-drive portion 24? on its forward end and the usual screw-threaded drive portion 24? on its rearward end. This arrangement allows the plunger to be pushed forwardly while the dosing drive mechanism is disengaged to effect a reconstitution movement of the rearward bung 18? in the cartridge. Thereafter the threaded portion on the plunger 24? engages the drive mechanism to allow metered dosing.Type: GrantFiled: March 29, 2012Date of Patent: July 16, 2013Assignee: Owen Mumford LimitedInventors: Jeremy Marshall, Steven Mark Guy Rolfe
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Publication number: 20130178802Abstract: An assembly for a drug delivery device comprises a housing, a rotation member, a drive member and at least one correction member. The rotation member is adapted to be rotated with respect to the housing in a first rotational direction for delivering a dose of a drug. The drive member is coupleable to the rotation member for delivering the dose. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in the first rotational direction due to mechanical interaction of the rotation member and the drive member.Type: ApplicationFiled: December 12, 2012Publication date: July 11, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: SANOFI-AVENTIS DEUTSCHLAND GMBH
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Publication number: 20130178803Abstract: A resettable drive mechanism for a medication delivery device comprising a housing, a drive member rotatable with respect to the housing in a second direction for delivering a dose of a medication, and a piston rod by the drive member, when drive member rotates in the second direction, a stop member adapted to prevent rotation of drive member in a first direction, when the stop member engages the drive member, a clutch member movable between a delivery position and a reset position. When clutch member is in the delivery position, stop member and drive member are engaged and drive member is prevented from rotation in the first direction, and when the cutch member is in the reset position, the drive member and the stop member are disengaged, the drive member is rotatable in the first direction.Type: ApplicationFiled: January 3, 2013Publication date: July 11, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: SANOFI-AVENTIS DEUTSCHLAND GMBH
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Patent number: 8480633Abstract: A pump drive and a method thereof to dispense a liquid drug from a container having a plunger piston are disclosed. The pump drive provides a unidirectional clutch provided about a rotational axis which supports centrally a wheel. The clutch has an inner race operably connected to the plunger piston, wherein the clutch is configured to rotate both the inner race about the axis in unison with rotation of the wheel in only a first direction to advance the plunger piston, and to let the wheel rotate relative to the inner race about the axis in a second direction opposite to the first direction without advancing the piston plunger. The drive in one embodiment includes at least one shape memory alloy wire which when excited rotates the wheel in the first rotational direction to advance the piston plunger and dispense the liquid drug from the container.Type: GrantFiled: April 30, 2012Date of Patent: July 9, 2013Assignee: Roche Diagnostics Operations, Inc.Inventor: Steven N. Roe
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Patent number: 8469930Abstract: A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained.Type: GrantFiled: June 16, 2011Date of Patent: June 25, 2013Assignee: Roche Diagnostics International AGInventors: Ulrich Haueter, Martin Wyss, Florian Kuehni
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Publication number: 20130158508Abstract: A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.Type: ApplicationFiled: January 30, 2013Publication date: June 20, 2013Applicant: ANTARES PHARMA, INC.Inventor: Antares Pharma, Inc.
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Publication number: 20130150803Abstract: A dose control mechanism for a syringe includes a plunger having a coarse pitch screw on its exterior surface, a housing having a corresponding coarse pitch guide along the interior surface of the housing, a screw having a fine pitch screw which interfaces with a fine pitch nut of an adapter, wherein the plunger has an internal annular space within which screw at least partially resides. An accurate dose drug delivery syringe includes such a dose control mechanism, a barrel, a plunger seal, and a barrel adapter assembly having a barrel tip and a needle. The syringe may be a fill-at-time-of-use syringe, a pre-filled syringe, or a safety syringe having integrated needle retraction or needle sheathing safety features, or a combination thereof. Methods of assembly, manufacturing, and operation are similarly disclosed.Type: ApplicationFiled: December 6, 2012Publication date: June 13, 2013Inventor: UNITRACT SYRINGE PTY LTD
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Publication number: 20130131605Abstract: A drive member and a rotation member are rotatable with respect to a housing. The drive member comprises drive fingers, which are resilient or resiliently mounted. A slider is disposed at the drive member and is axially movable between a first position, in which the slider keeps the drive fingers constrained, and a second position, in which the drive fingers are released. A unidirectional rotational clutch engages the drive member with the rotation member. The clutch is formed by the drive fingers when the slider is in the first position. The drive member and the rotation member are disengaged when the slider is in the second position. The slider is in the first position when a unit is attached to the housing, and in the second position when the unit is removed.Type: ApplicationFiled: June 9, 2011Publication date: May 23, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: John Hiles
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Patent number: 8444606Abstract: The invention concerns an injection device for apportioning set doses of a drug from a reservoir to a subject. The injection device comprises a housing having an interior thread formed as an outwardly pointing thread carried on an upstanding tower centrally located in the pen shaped device. This outwardly pointing thread forms a first thread connection with the interior thread of the rotatable scale drum. The injection device further comprises a driver for moving the piston rod forward when moved axially. The driver operates the piston rod through a second thread connection having a pitch different than the first thread connection.Type: GrantFiled: November 13, 2009Date of Patent: May 21, 2013Assignee: Novo Nordisk A/SInventors: Bo Radmer, Claus Schmidt Moller, Lars Morch Groth, Klaus Thogersen
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Patent number: 8444607Abstract: A delivery device includes first and second housing portions that selectively engage and disengage. A reservoir on one housing portion operatively engages a drive device and/or a needle inserting device on the other housing portion. Upon proper engagement of the housing portions, the reservoir operatively couples to the drive device and/or the needle inserting device. A first magnet on the first housing portion and a second magnet (or a magnetically-attractive material) on the second housing portion are positioned to magnetically interact with each other, upon operative engagement of the housing portions. A third magnet on the second housing portion may be opposed to the first magnet to help align the housing portions for connection. A magnet-responsive device may be on one or both housing portions to detect alignment and/or connection of the housing portions.Type: GrantFiled: October 8, 2008Date of Patent: May 21, 2013Assignee: Medtronic MiniMed, Inc.Inventors: R. Paul Mounce, Melissa D. Norton, Robert M. Guezuraga, Bradley J. Enegren, Paul F. Bente, IV, Ian B. Hanson, Julian D. Kavazov, Christopher G. Griffin, Sheldon B. Moberg, Mark D. Holt, Susie E. Maule, Paul H. Kovelman
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Publication number: 20130096513Abstract: A semi-automatic “fixed” dose injection device is disclosed containing a reservoir of medicament, where a trigger controls the unwinding of a torsional spring to cause a predetermined injection of medicament from the reservoir through a disposable needle.Type: ApplicationFiled: February 15, 2011Publication date: April 18, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: Christopher James Smith
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Patent number: 8419691Abstract: Methods and devices for micro-dosing a liquid are disclosed herein. According to one embodiment, a method for a time controlled micro-dosing of a liquid from a liquid reservoir includes: receiving the liquid reservoir with a structure wherein the structure is portable; securing the liquid reservoir to the structure; connecting a second end of a drive unit to a piston disposed within the liquid reservoir; activating a drive motor; displacing the drive unit with respect to the structure towards the piston in an axial direction with the drive motor; moving the piston axially within the liquid reservoir; and micro-dosing the liquid from the liquid reservoir.Type: GrantFiled: June 18, 2010Date of Patent: April 16, 2013Assignee: Roche Diagnostics International AGInventors: Roger Haenggi, Hanspeter Niklaus
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Patent number: 8419692Abstract: An injection device comprising a housing and a dose setting mechanism including a dose setting element. Contrary to prior art injection devices, the dose setting element can only be set at a few different dose settings. This is established by forming the dose setting element as a rotatable dish concealed within the housing and having a number of projections projecting outside the boundaries of the housing through a slot in the housing. A dose is set by activating a projection which in addition provides the user with a tactile guidance. Usually one projection is provided for one dose setting limiting the number of doses to be set to the number of projections.Type: GrantFiled: June 17, 2010Date of Patent: April 16, 2013Assignee: Novo Nordisk A/SInventors: Thomas Dedenroth Miller, Steffen Hansen, Niels Christian Egholm Sorensen
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Patent number: 8409148Abstract: A device for the dosed administration of a fluid product including a housing, a conveying device for the product, a drive element influenced by the selection of a product dose, a coupling input member coupled to the drive element, a coupling output member coupled to the conveying device, a retaining device which maintains the coupling elements in a maintaining position uncoupled from each other, wherein at least one of the coupling elements is displaceable by a coupling movement from the maintaining position into a coupling state, and wherein a driving force of the drive element causes a delivery movement of the conveying device via the coupling elements.Type: GrantFiled: June 27, 2007Date of Patent: April 2, 2013Assignee: TecPharma Licensing AGInventors: Patrick Fiechter, Philippe Kohlbrenner, Daniel Kuenzli, Christof Meier, Peter Stettler, Juergen Wittmann, Urs Widmer
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Publication number: 20130079728Abstract: A medication dispensing device with a housing and a member wherein the member is moveable in a distal direction is useful in delivering medication to a patient. A fluid container can be used with the device and often has a moveable piston at one end and an outlet at the other. The member receives a force from a user and drives the piston in the distal direction to expel medication. A intermediate system is disposed between the member and the piston including a gear set that has a pinion in meshed engagement with a rack. The system allows the member to move a greater distance than the piston moves thereby increasing the force on the piston.Type: ApplicationFiled: November 21, 2012Publication date: March 28, 2013Applicant: NOVO NORDISK A/SInventor: NOVO NORDISK A/S
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Publication number: 20130053789Abstract: The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having dose setting means and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge, to a use of such device, and to a method of manufacturing or assembling such device.Type: ApplicationFiled: March 9, 2012Publication date: February 28, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Michael Harms, Steffen Raab, Dominic George Webber, James Robert Howarth, Trevor John Beckett, Geoffrey Philip Gray, John David Cross
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Publication number: 20130046247Abstract: An assembly for a drug delivery device (1) comprises a housing (5), a rotation member (15), a drive member (16) and at least one correction member (7). The rotation member (15) is adapted to be rotated with respect to the housing (5) in a first rotational direction for delivering a dose of a drug (11). The drive member (16) is coupleable to the rotation member (15) for delivering the dose. In a delivery mode, the drive member (16) and the rotation member (15) are coupled such that the drive member (16) follows rotational movement of the rotation member (15) in the first rotational direction due to mechanical interaction of the rotation member (15) and the drive member (16). In a correction mode, the rotation member (15) and the drive member (16) are decoupled such that the rotation member (15) is rotatable in the first rotational direction with respect to the drive member (16).Type: ApplicationFiled: November 1, 2010Publication date: February 21, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Philippe Nzike, Steffen Raab, Uwe Dasbach, Uwe Boeser, Ulrich Bruggemann
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Publication number: 20130046248Abstract: An assembly for a drug delivery device comprises a housing, at least one stop feature and at least one blocking member. For setting a dose of a drug, the stop feature is configured to be rotated in a dose setting direction with respect to the blocking member and with respect to the housing. For delivering the set dose of the drug, the blocking member is configured to be axially displaced with respect to the stop feature away from an axial starting position and towards an axial interaction position. When the blocking member is in the axial starting position, the blocking member is axially offset from the stop feature and, when the blocking member is in the axial interaction position, the blocking member is configured to mechanically cooperate with the stop feature such that rotation of the stop feature in the dose setting direction with respect to the housing is prevented.Type: ApplicationFiled: February 2, 2011Publication date: February 21, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: Steffen Raab
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Publication number: 20130046249Abstract: An injector apparatus includes a housing (101, 102) for a cartridge or syringe, a plunger (40) for cooperating in use with the cartridge or syringe to express successive doses, a dose setting arrangement (16, 20) to select a dose volume, and a drive mechanism (22, 24) releasable to advance the plunger in respective predetermined increments of magnitude to express the successive doses. The drive mechanism includes a drive spring (22) for imparting movement directly or indirectly to the plunger (40), and the dose setting arrangement includes a dose setting element (16) moveable in a dose setting routine to define a magnitude of an increment of movement of the plunger for a given dose. The drive mechanism further includes a clutch arrangement (56) operable during the dose setting routine to inhibit forward movement of the plunger and/or to isolate the dose setting element from the force of the drive spring.Type: ApplicationFiled: October 15, 2010Publication date: February 21, 2013Applicant: OWEN MUMFORD LIMITEDInventor: Toby Cowe
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Patent number: 8377004Abstract: A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug deliver pump.Type: GrantFiled: February 28, 2011Date of Patent: February 19, 2013Assignee: Roche Diagnostics Operations, Inc.Inventors: Christopher Wiegel, Marco De Polo, Steven Roe
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Publication number: 20130041322Abstract: A medicament delivery device has proximal and distal housing parts connected along a longitudinal axis, the proximal part for accommodating a medicament container. A drive member inside the distal part has a first circumferential set of interacting devices. A longitudinal plunger rod is rotationally locked through a central passage of the distal part, acts on a stopper inside the container, and is connected to the plunger rod. A turnable dose setting member coaxially arranged around the drive member is rotatably connected to the distal part. A torsion spring is connected to the dose setting member and to a hub of the drive member. The hub, spring, dose setting member, and drive member are coaxial transversally. The drive nut has second interacting devices on its outer surface. When the drive member is rotated by the spring, the drive nut rotates, whereby the plunger rod moves proximally for expelling a dose of medicament.Type: ApplicationFiled: April 14, 2011Publication date: February 14, 2013Applicant: SHL GROUP ABInventor: Anders Holmqvist
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Patent number: 8366680Abstract: A resettable drive mechanism comprising a housing, a drive member rotatable in a second direction for delivering a dose of a medication, a piston rod driven by the drive member when it rotates in the second direction. A stop member prevents rotation of the drive member in a first direction opposite to the second direction, when the stop member engages the drive member. A clutch member is movable between a delivery position and a reset position. When the clutch member is in the delivery position, the stop member and the drive member are engaged and the drive member is prevented from rotating in the first direction, and when the clutch member is in the reset position, the drive member and the stop member are disengaged, the drive member is rotatable in the first direction and the piston rod is movable in the proximal direction.Type: GrantFiled: December 12, 2008Date of Patent: February 5, 2013Assignee: Sanofi-Aventis Deutschland GmbHInventor: Steffen Raab