Abstract: A system for automatically metering a predetermined dosage of a medicament from a cartridge. The system includes a tubular cartridge containing the medicament and a plunger which is movable in the cartridge to dispense the medicament through one end. The cartridge further includes an interior tab (e.g. a ring) for stopping forward movement of a detent carried by the trigger of a syringe body in which the cartridge is positioned. By limiting forward movement of the detent, forward movement of the plunger rod is also stopped, thereby controlling the amount of medicament dispensed from the cartridge.

Abstract: An ampule having a body portion and a sealed end portion and a sealed delivery portion adapted for use in a delivery syringe system for controllably dispensing a low viscosity material, such as a liquid, gel, or paste. An ampule having sealed rear portions adapted to mate with a plunger of a syringe so as to facilitate controlled dispensing of a low viscosity material. The syringe has a breach positioned to provide controlled flow of the dispensed low viscosity material and facility easy removal from the syringe. Low viscosity materials, such as liquids and gels, are controllably dispensed in a measured unit dose quantity. The present invention has many applications, but is particularly applicable to dispensing low viscosity materials such as used in coatings and not injected parenterally, and is particularly applicable to dental applications.

Abstract: The invention relates to: A medication delivery device and a method of making such a device. The object of the present invention is to provide a handy medication delivery device that may be easily adjusted to the different needs of a given user in different situations and to the different needs of different users, and which is economic from a production point of view. The problem is solved in that it comprises a basis module (1) and one or more replaceable modules (2, 3, 4, 5, 6), each of which is adapted to cooperate mechanically and/or electronically with the basis module to provide a specific function, and the basis module includes resources that are jointly used by the replaceable modules. This has the advantage of providing a rational concept for economically supplying high quality, mass-produced devices capable of being customized to individual users' needs for functionality by avoiding the duplication of key components.

Abstract: Foil bags are used as a primary packaging for liquids, the bags permitting the liquid to be taken therefrom without the application of a considerable amount of force. A container is provided for a medicinal liquid, the container being gas-tight and liquid-tight so that it is storable over many months. The container includes a collapsible foil bag on which a flange, which is stable in respect of shape, is disposed. The flange is designed for fitting onto a discharge connection member. The container can be disposed in a casing which is stable in respect of shape. The medicinal liquid does not come into contact with air and is protected from the effect of light. The medicinal liquid may be dispensed from the foil bag in many partial quantities over a prolonged period of time, with a respective partial amount thereof being converted into an aerosol by means of an atomizer.

Abstract: A fluid injection arrangement, in the context of patient imaging systems, in which phases of contrast medium injection and flushing medium injection can be freely and selectably ordered so as to make available to the operator and patient a vast array of possible protocols that has hitherto been essentially unattainable. Also contemplated is the use of a “hold” phase, involving an indefinite pause between phases of a protocol, in connection with such imaging systems. Further contemplated is the use of a “pause” phase in which a pause of fixed duration is pre-programmed into the protocols of MRI injector systems.

Abstract: A multi-chamber ampoule comprises a container having at least one movable partition therein, the movable partition being adapted to sealingly isolate at least two substances to be mixed with each other, a seal or plunger movably disposed in the container, a holder connected to the container, and a screw actuator engageable with the seal or plunger for displacing the same in the container. The screw actuator has a male thread, and the holder includes a female thread engageable with the screw actuator male thread. The screw actuator is provided with a bore therethrough for slidably receiving a dispensing rod.

Abstract: Prefilled, disposable syringes for injecting preparations with a fill volume of less than 5 ml are typically made of glass. The disposable syringe in this invention avoids the use of glass as a construction material. The body of the syringe with barrel, grip and nozzle is made of transparent, glass-like plastic with a very low gas permeability and is designed to be resistant to gamma rays and/or ethylene oxide gas, whereby the hypodermic needle is directly integrated within the plastic nozzle.

Abstract: A needleless injector cartridge has an adaptor for introducing fluid from a filling device into an orifice of the cartridge. The adaptor has a frangible connection which is broken to allow removal of the filling device after the cartridge is filled with the fluid.

Abstract: Replaceable components for use with a needleless syringe delivery device are provided. One replaceable component is a cartridge having a source of particles and a source of compressed gas. Another replaceable component is a nozzle assembly having a particle acceleration nozzle and a coaxial filter element. Reusable needleless syringe devices which include these replaceable components are also provided.

Abstract: An ampule having a body portion and a sealed end portion and a sealed delivery portion adapted for use in a delivery syringe system for controllably dispensing a low viscosity material, such as a liquid, gel, or paste. An ampule having sealed rear portions adapted to mate with a plunger of a syringe so as to facilitate controlled dispensing of a low viscosity material. The syringe has a plunger adapted to grasp the collapsed ampule, facilitating removal, as well as breach openings positioned to provide controlled initial flow of the dispensed low viscosity material. In one embodiment, a barrel having different internal diameters is used to improve dispensing of material within an ampule. Low viscosity materials such as liquids and gels are controllably dispensed in a measured unit dose quantity.

Abstract: A cylinder ampoule (1) having a first end sealed by a closure through which an injection unit can communicate with a medicament in the ampoule and a second end closed by a piston (3) which can be forced into the ampoule (1) to press out a dose of a medicament stored in the ampoule between the closure and the piston (3) through said injection unit, which cylinder ampoule (1) has a non-circular inner cross section and which piston (3) has a non-circular cross section corresponding to the inner cross section of the ampoule (1). A piston rod (4) has a pressure foot (5) which has a cross section corresponding to the inner cross section of the ampoule (1) and is non-rotatably connected to the piston rod (4).

Abstract: For filling a syringe firstly the syringe cylinder is filled with a fluid or a pasty substance, whereafter the syringe piston is introduced. Via an opening in the base of the syringe piston the air located in the syringe cylinder is removed, whereupon the opening is closed.

Abstract: A syringe type ampoule having a) a barrel with a front end and a rear end defining an axis therebetween, the barrel having substantially constant cross-section between the front end and the rear end, at least the front end ending in an opening, b) a sealer attached to the front end and sealing the opening, c) at least one piston movably and sealingly arranged within the barrel and d) a sleeve extending along at least a part of the barrel, the sleeve having a front part and a rear part, the front part being connected to the sealer. The barrel has a front end terminating in an edge surrounding the opening, the edge having an outer circumference substantially equal to the barrel outer circumference. The invention relates to methods and means for manufacture of pre-filled such ampoules or other ampoules.

Abstract: A system is provided for the storage and injection of a beneficial agent. The system includes a barrel, the barrel having a loading end and a distal end, and a piston having an elastomeric portion slidably disposed in the barrel bore. A receptacle pre-filled with the beneficial agent is loaded into the loading end of the barrel and is movable with the piston. A tubular flow connector is carried by the piston for connecting the receptacle to a distal chamber of the barrel so that the agent can flow from the storage receptacle into the distal chamber when the piston is retracted away from the distal end of the barrel. A structure is provided along a portion of the receptacle to allow the agent to flow from the receptacle, through the flow connector and into the distal chamber without being inhibited by the development of negative pressure within the receptacle.

Abstract: A needleless injector drug capsule assembly comprising a container, housing therefor, a piston, and resilient seals to permit filling and sealing thereafter to maintain sterility of the contents.

Abstract: Assembly for the distribution of a pharmaceutical solution, contained in multi-dose vial, into single-dose carpules for single use, comprising single-dose carpules and a distribution apparatus, in which assembly pressure and suction means are provided to circulate a liquid from the carpules to the vial and from the vial to the carpules, by means of a network of channels.

Abstract: An injection device for injecting a preselectable dose of a liquid substance from an ampoule (2) with a stopper (12) located in an ampoule-holder (1) has a sleeve-shaped mechanism holder (3) mechanically linked to the stopper (12) and containing a sliding rod (4) which acts on the ampoule (2). The sliding rod (4) is surrounded by a sliding sleeve (5) mechanically coupled to the ampoule (2) and closed at its upper end by a lid (7). A dosing sleeve (13) is provided with a stepped member (13) arranged at the upper end of the mechanism holder (3) to preselect the dose of liquid substance to be injected. The dose to be administered can be adjusted by turning the dosing sleeve (6) provided with the stepped member (13).

Abstract: A syringe type ampoule having a) a barrel with a front end and a rear end defining an axis therebetween, the barrel having substantially constant cross-section between the front end and the rear end, at least the front end ending in an opening, b) a sealer attached to the front end and sealing the opening, c) at least one piston movably and sealingly arranged within the barrel and d) a sleeve extending along at least a part of the barrel, the sleeve having a front part and a rear part, the front part being connected to the sealer. The barrel has a front end terminating in an edge surrounding the opening, the edge having an outer circumference substantially equal to the barrel outer circumference. The invention relates to methods and means for manufacture of pre-filled such ampoules or other ampoules.

Abstract: A syringe having a retractable needle includes a carpule fitted within a hollow interior portion of a housing. The carpule includes first and second open ends and a needle-retaining member and a fluid-expelling member within the first and second ends to define a fluid chamber therebetween. The needle-retaining member is positioned adjacent a front end of the housing to allow one end of a needle to be inserted through the needle-retaining member and into the fluid chamber. A plunger pushes the fluid-expelling member forwardly to force substantially all the fluid within the fluid chamber through the needle. An attachment member fixed to the fluid-expelling member securely engages the needle-retaining member as the fluid chamber is emptied and the fluid-expelling member contacts the needle-retaining member.

Abstract: The invention relates to an injection device (10) having a housing (15) and an injection fluid container (12) which can move, in relation to this housing, between a distal and proximal end position, and also having a pushrod (14) to act on a plunger (23) in this container (12) for the purpose of expelling fluid from the container. A drive connection (27) is provided between the pushrod (14) and the container (12) and, in the distal end position of the container, this drive connection is effective in both the proximal and the distal direction, but in the proximal end position of the container (12), it is only effective when the pushrod (14) is moved in the distal direction.

Abstract: A method for lubricating a sealing member and a medicament chamber in a drug delivery device includes providing lubricating silicone on the surface of the stopper and within the plastic material of the chamber. The stopper preferably is first washed and rinsed in hot deionized water followed by drying. The dried sealing member is then tumbled with polymeric silicone and then irradiated at a target dose between 2.5 to 4.0 Mrads to cause the silicone molecules to bond with the elastomeric material of the stopper. The irradiated sealing members are then loaded in any of a series of chambers including syringes, pre-filled syringes, drug cartridges, and needleless injector ampules. The chamber preferably is made from a plastic material that has been mixed with a lubricating solution such as silicone when the plastic is compounded.

Abstract: The present invention relates to improvements on automatic injection devices, in particular for self-administered drug therapies, providing for a high degree of internal stability of the syringe and, therefore, of the associated needle, thanks to a series of elastic wasp-waisted elements and a mobile tip made of a transparent material in the preferred embodiment, which besides enabling the regulation of the length of projection of the needle during the injection also allows the user to see the exact spot where the needle will enter the flesh.

Abstract: A multi-use medication dispensing pen made of a plastic material that is recyclable after the contents of the medication cartridge have been exhausted. The pen is made of a minimal number of parts, which include a housing, a dial mechanism, a generally cylindrical button assembly located within the proximal end of the dial mechanism, an internally threaded nut, and an externally threaded leadscrew. The pen is arranged so that the dial mechanism must be rotated to the zero-dose position prior to setting a dose. The pen includes a lockout mechanism that prevents the dial mechanism from being inadvertently depressed during dosing. The pen further includes a mechanism that limits the maximum dosage that can be dialed up and a mechanism that prevents the user from dialing up a dosage greater than that remaining in the cartridge.

Abstract: A single use retractable medical device dispenses fluids from a separable carpule. A retraction mechanism having a spring loaded needle holder with a double ended needle is mounted in the front of a housing by means of a push ring (separable member) slidingly mounted on a widened portion of the needle holder. An outer edge of the push ring grips or is restrained by the inner wall surface of the housing to hold the needle holder in place. A carpule positioned through an opening in back of the housing is operated by a plunger which drives a separable two-part piston to unload medicine from the carpule through the needle. At the end of an injection, the plunger is depressed further. The carpule moves forward to remove the push ring thereby freeing the needle holder for retraction into the carpule through the front opening of the carpule. As the needle is retracted into the housing from one end, the edge of the thumb cap of the plunger disappears into an opening at the opposite end of the housing.

Abstract: The present invention relates to a system for locking a dosing button in a device for the administration of a product to be injected in predetermined doses. This device comprises a body (1) with a housing (2) for the product, wherein a selected dose for injection is transported from said body out of a container (3) through a transport member (4). This device also comprises a drive member (5,7) for the transport member (4) as well as a dosing button (9) coupled to the drive member (5, 7) which is mounted so as to be capable of sliding within the body (1). The button ensures the transport of the selected dose when it is displaced from a first position into a second by actuating the drive member (5, 7). The dose is selected in the first position by rotating the dosing button (9) so that is can be moved from a first rotation position indicating that no transport is possible into a second rotation position.

Abstract: Dimensionally stable plunger rod for use with a plunger in a cartridge or syringe barrel for manual or power-assisted withdrawal of fluid from a site or expelling fluid from the cartridge or syringe barrel having: a plunger rod body with a distal and a proximal end: an end disc at the distal end; a threaded member integral with the end disc designed to engage a plunger; a thumb rest at the proximal end; four longitudinal radially extending rectangular vanes connected to the end disc at the distal end, and to the thumb rest at the proximal end; two pairs of longitudinal radially extending reinforcing vanes forming two triangular configurations with one of the longitudinal radially extending rectangular vanes on one side of the plunger rod body; and two pairs of longitudinal radially extending reinforcing vanes forming two triangular configurations with another of the longitudinal radially extending rectangular vanes on the opposite side of the plunger rod body, each of the pairs of the reinforcing vanes

Abstract: An improved guard for a medical cartridge, such as a unit dose pre-filled glass syringe, comprising a body for receiving the cartridge, and a shield slidably attached to the body which are pre-assembled and ready to receive a cartridge therein. The body has a locking mechanism on a proximal end thereof which holds the cartridge therein. The body and shield have cooperating detents and detent pockets which allow the shield to be directed distally, from an unguarded position in which the needle on the cartridge is uncovered for delivery of medication, to a guarded position in which the needle is permanently covered for disposal. The body may also include a substantially rectangular-shaped finger grip on its proximal end for receiving a similarly shaped proximal flange on the cartridge, whereby the cartridge is received in a predetermined orientation. The body may also include one or more ribs within the cavity for accommodating a cartridge with a large needle cap, such as a 0.5 mL capacity pre-filled syringe.

Abstract: A needle assembly for a medication delivery pen having a 31 gauge needle cannula that reduces penetration force during an injection process resulting in less pain to the patient without causing any loss in performance or structural integrity.

Abstract: A holder has an inner diameter which allows the holder to be fitted onto the outside of a cylinder barrel 2 and is formed into a tubular shape having a length which is substantially equal to that of the cylinder barrel 2. The holder has a flange 73 at the basal end.

Abstract: A plastic adaptor top for adapting to a chosen syringe a standard cartridge of the kind having a neck with a flange and being closed by a rubber membrane sealingly secured against the flange by a metal cover having its edge beaded behind the flange. This plastic top has a bore for receiving the neck part of the cartridge, which bore has a diameter making it fit over the metal cover and is provided with protrusions gripping behind the edge of the metal cover when the neck part is inserted in the bore. The outer contour of the adaptor top is provided with threads coaxial with the bore to receive a needle hub in a way causing the needle to penetrate the membrane of the cartridge when the hub is mounted on the thread of the plastic top.

Abstract: A cartridge for containing a fluid and for use with an electronic delivery device, includes a cartridge housing for holding the fluid, and information providing source. The information providing source is coupled to the cartridge housing to operatively couple with the electronic delivery device to provide predetermined information regarding the cartridge to the electronic delivery device. For example, the information providing source may be a set of wires and contacts, or contact bands, that provide the predetermined information to electronic delivery device by producing a binary code. Alternatively, the information providing source is a bar code that provides the predetermined information to electronic delivery device by reading of the bar code. The cartridge may be used in a system that includes an electronic delivery device, such as an electronic pen-type injector and/or infusion pump.

Abstract: An injection device is described which is lockable in its end position in such a manner that the reliability of storing or transporting it with a carpule attached is improved in comparison with devices according to the prior art. It is comprised of fewer components than comparable devices, with these components being easier to manufacture so that production costs are low. The injection device is used for medical purposes.

Abstract: The present invention is a single use injector device for injecting parenteral medications which operates by hand force. The injector device has a plunger section and a base. As hand force is applied to a moving portion of the plunger section, break tabs or a snap ring resist its motion toward the patient's skin surface. The break tabs or snap ring release abruptly as the hand force reaches a snap point. The motion of the moving portion then drives the medication through the skin surface and into the body of the patient. If the medication is in liquid form, the actual injection may be carried out through a hollow needle attached to the plunger section. Alternatively, the suddenly increased pressure of the medication at the snap point may be used to form a liquid jet for needleless injection. Part or all of the medication may be contained in a glass needle which dissolves in the body after injection. The injector device requires little training to use, reduces perceived pain, and improves injection safety.

Abstract: A dual port syringe has an upper port for connection to a fluid reservoir and a lower port for delivery of the medical fluid under pressure to a patient. A first valve is connected between the fluid reservoir and the upper port, and second valve is connected between the lower port and the patient. During a fill operation, a piston is moved within the syringe to drawn fluid from the reservoir into the syringe through the upper port. During injection operation, the piston moves in an opposite direction to force fluid out of the syringe through the lower port.

Abstract: A reloadable auto-injector including a housing portion (1, 101) designed to receive a syringe (3), and a cover portion (2, 102), the auto-injector incorporating an injection device for automatically injecting the substance contained in the syringe, the injection device comprising: a piston (21) comprising a high portion (21b) and a low portion (21c), the low portion (21c) co-operating with the plunger of the syringe, the piston (21) being mounted to move, under the effect of an actuating spring (22) between a cocked position and an end-of-stroke position, the spring (22) being compressed in the cocked position; and trigger means (19) mounted to move between a blocking position in which they hold the piston (21) in its cocked position, and a releasing position in which they release the piston (21), the trigger means (19) being released from their blocking position by an actuating member; the auto-injector being characterized in that it further includes recocking means for recocking the automatic injection devi

Abstract: A dispensing cartridge for use with a hand-held applicator has a chamber with a first section and a second section. The second section has a smaller cross-sectional area than the first section such that the chamber has a stepped configuration. A piston is slidably received in the chamber and has a head portion that is received in the second section and a tail portion that is received in the first section. As a force is applied to the tail portion, the head portion advances to expel material through an outlet opening. The cartridge is especially useful for dispensing compositions having a relatively high viscosity such as dental pastes and the like.

Abstract: A blood-collection apparatus has a needle having a sharp front end and a sharp rear end, a mounting collar on the needle between its ends and a holder tube extending along an axis and having front and rear ends. A piston axially slidable in the holder tube is provided with a mount adapted to fit complementarily with the mounting collar with the needle rear end directed axially back in the tube. The piston normally is at the tube front end with its mount projecting axially forward from the tube. A flexible strand has a front end attached to the piston and a rear end projecting from the tube rear end. This mount is fitted into the needle's collar after the blood-collection operation is complete so that a pull on the strand retracts the piston back into the tube carrying the needle fitted to its mount.

Abstract: A hypodermic syringe for medical, dental or veterinary use of a conventional nature or employing prefilled cartridge ampules of injectable fluid. The syringe is arranged to allow the operator to automatically sense the amount of pressure being manually exerted by thumb pressure to express the fluid from the ampule or a fluid chamber into the patient. A slender elongated plunger mounted within the main body of the syringe is slidably moveable by thumb pressure against a thumb ring disposed at a distal end of the plunger. A spring-biased pressure indicator member is slidably moveable rearwardly for limited longitudinal movement with respect to the thumb ring and is deflected into the thumb of the operator a distance proportional to the fluid pressure at the syringe needle tip. The operator can thus sense indicia of fluid pressure produced while pressing the thumb ring to make an injection.

Abstract: An improved single- or multiple-dose syringe having a conventional housing and an improved plunger configuration carrying a medicament- or saline-filled cartridge the contents of which are sequentially dispensed after the dispensing of a volume of a drawn-up primary fluid. A method for sequential administration of medicinal fluids using the improved syringe is also a part of the invention.

Abstract: The present invention provides an injection system including a disposable lower part and a reusable upper part wherein the lower part includes an ampoule holder for accommodating a container containing a liquid medicament and having an axially movable plug having a cross-section F for ejecting the liquid medicament from the container and a kinematic device for axially driving the plug forward by a number N of individual steps x, N being a natural number, and the reusable upper part includes a casing detachably connectable to the ampoule holder, and a dosing button for selecting the number N of individual steps x and for actuating the kinematic device of the lower part which thereby effects selectable ejection of a Volume V=NxF of the liquid medicament from the container.

Abstract: A needleless jet injection device including a barrel fitted with a cap at one of the ends thereof. Relative motion of the cap component actuates a setting device operably connected to a precussive member. A cartridge arranged at the other end of the barrel comprises two elements, i.e., a first element forming a container for the active principle, and a second element consisting of a plastic shell enclosing the first element.

Abstract: A low cost safety sterile cartridge injector apparatus comprising an injector and a safety needle sheath having elements which promote facile assembly and disassembly. An embodiment is disclosed which incorporates an integral needle hub and safety sheath which is displaced to protectively cover a medical needle after use. The sheath also incorporates patterns of rachet teeth which cooperate with a holder portion of the injector to lock a sterile cartridge in place for use in a medical procedure and to release the cartridge for facile disposal when the sheath is displaced to cover and protectively shroud the needle after use. Through this process, need for rotary collars to capture and hold the cartridge in place during use is eliminated, reducing injector cost and apparatus assembly steps and time.

Abstract: The invention relates to a process for manufacturing an injection device of the pre-filled type comprising producing, in a deformable plastics material, a tubular syringe body (101) equipped with an external locking element (104) suitable for deforming radially between retracted and dilated positions, producing a tubular sheath (109) equipped with an internal locking element (110, 111) paired with that of the syringe body (101), fitting the sheath (109) round the syringe body (101), by a relative sliding of these latter permitted by the radial retraction of the locking element (104) of the syringe body (101), and introducing into the syringe body (101) a rigid pre-filled container suitable for bringing the locking element (104) of the said syringe body into its dilated position, enabling an irreversible locking of the sheath (109) to be obtained once it has been brought, after injection, into an advanced, post-use protection position.

Abstract: Dimensionally stable plunger rod for use with a plunger in a cartridge or syringe barrel for manual or power-assisted withdrawing of fluid from a site or expelling fluid from the cartridge or syringe barrel having:a plunger rod body with distal end proximal ends;an end disc at the distal end;a threaded member integral with the end disc designed to engage a plunger;a thumb rest at the proximal end;a reinforcing disc at about the longitudinal mid point of the plunger body;a first pair or rectangular radially extending vanes connecting the end and reinforcing discs;a second pair or rectangular radially extending vanes connecting the reinforcing disc and the thumb rest;a first pair of triangular radially extending vanes connecting the end disc and the reinforcing disc; anda second pair of triangular radially extending vanes connecting the reinforcing disc and the thumb rest.

Abstract: A guard for a medical cartridge, such as a pre-filled syringe, includes a body having an open proximal end communicating with a cavity for receiving the cartridge, and a shield slidably attached to the body. The body has a semi-rigid cantilever member on its distal end from which a stop tab, having a sloped distal edge and a blunt proximal edge, extends. The shield includes an elongate opening for receiving the stop tab, thereby allowing the shield to slide between unguarded and guarded positions for exposing and covering a needle, respectively. During assembly of the shield and body, the stop tab slidably engages an assembly tab on the shield, deflecting the cantilever member inward while the stop tab passes under the shield, the sloped distal edge of the stop tab minimizing damage to the stop tab or shield. In the guarded position, the blunt proximal edge of the stop tab engages a proximal wall of the elongate opening to prevent further distal movement beyond the guarded position.

Abstract: A syringe type apparatus which includes a unique fill assembly for use in controllably injecting medicinal fluids into a patient. The filling assembly includes a prefilled vial which is partially received within a novel adapter assembly that functions to operably couple the prefilled vial with the syringe assembly of the apparatus. The body of the prefilled vial is surrounded by a protective covering until immediately prior to mating the assembly with the syringe assembly.

Abstract: A prefillable syringe includes an elongate barrel having an open distal end and a proximal end with at least one chamber formed therebetween for receiving a substance sensitive to pH shift, such as water for injection. The barrel is made of a low extractable ion glass preferably having a low concentration of sodium of less than 8% and preferably around 4% or less.

Abstract: A spring-actuated infusion syringe includes a housing having an open distal end, with a spring-loaded piston disposed for axial translation in the housing. The piston is biased toward the distal end of the housing. The syringe also includes a barrel for containing a liquid medicament, the barrel having a distal end having a fluid passage therethrough and an open proximal end. A plunger is disposed in the barrel for axial translation therein. The proximal end of the barrel is axially insertable into the distal end of the housing, whereby the piston enters the proximal end of the barrel and engages the plunger. In use, the barrel is filled with a medicament through the fluid flow passage, and the flow of medicament from the syringe is obstructed. The proximal end of the barrel is inserted into the distal end of the housing, whereby the piston enters the proximal end of the barrel.

Abstract: A medication cartridge for use with a medication delivery pen having a cartridge body with threads at its distal end for receiving a pen-needle. The threads are either integrally molded in the cartridge or on the outer surface of a cap used to retain a septum on the distal end of the cartridge body. The cartridge body of the medication cartridge also includes threads or a snap-ring at its proximal end for attaching the medication cartridge directly to a pen body housing of the medication delivery pen without the need for a medication cartridge holder.

Abstract: There is disclosed herein a syringe with a protector case which holds a carpule and permits the injection of fluid contained in the carpule into the patient. The syringe is molded of plastic or other suitable material which is sterilizable. The device comprises several parts including a body, protector case, needle, needle cap, plug, plunger and harpoon. The harpoon can be integrally molded on the plunger. The major components of the device preferably are molded from a suitable plastic and may be clear or of a color like or similar to a surgical glove.