Abstract: The present invention relates to the field of LED light strip. This invention provides an LED light strip, which includes a flexible protective sleeve and a soft light board, at least one protective circuit being arranged on the soft light board. The soft light board includes in sequence a first insulating soft film, an LED light source and a second insulating soft film. The protective circuit is provided with a zener diode or a voltage stabilizing unit which is connected in parallel with the at least LED light source and which maintains the electrical circuit to be on to keep the soft light board in operation when the LED light source is disconnected. When one or some of the LED light sources is/are damaged, the protective circuit conducts electricity in place of the damaged LED light sources, the LED light strip can continue to be energized and emit light.

Abstract: A stent device delivery system and method of making. The stent device delivery system includes a stent device and an outer sheath overlaying the stent device in a radially compact, delivery configuration of the stent device. The outer sheath may include a first layer of polymeric material and a reinforcement layer of polymeric material that are laminated together.

Abstract: A specimen retrieval system includes a bag having a flexible basket with an opening configured for receiving a tissue specimen, an elongate tail extending from the flexible basket, a primary loop attached to a proximal end of the tail opposite the flexible basket, and a string encircling the flexible basket and extending therefrom along the tail and terminating exterior of the proximal end of the tail, the string being operable to close the opening of the flexible basket. The system also includes an outer cannula having a distal end and a proximal end with a cannula handle located at the proximal end of the outer cannula, the outer cannula configured to receive the bag therein via the distal end of the outer cannula, with the tail of the bag, the primary loop and a portion of the string extending out of the proximal end of the outer cannula.

Abstract: An overtube to be inserted into a body wall is provided with an endoscope insertion passage and a treatment tool insertion passage, the treatment tool insertion passage is provided parallel to a reference axis of the overtube, and the endoscope insertion passage is provided obliquely to the reference axis. A slider, which is engaged with the endoscope and the treatment tool inserted through the respective insertion passages and causes the endoscope and the treatment tool to interlock with each other and move forward and backward, is arranged inside the overtube so as to be movable in a forward-backward direction of the overtube. An endoscope engagement part engaged with the endoscope in the slider is movable in an upward-downward direction, and moves upward and downward along the position of the oblique endoscope insertion passage together with the movement of the slider in the forward-backward direction.

Abstract: An apparatus for reversely deactivating a port seal in a laparoscopic port and providing a continuous passage between the laparoscopic port and a remote location in a body cavity.

Abstract: Valve retainers and delivery systems with valve retainers are disclosed. In certain embodiments, a portion of the valve retainer can rotate about a central axis of the delivery system relative to a different portion of the valve retainer. In certain embodiments, a first portion of the valve retainer can include a plurality of first orientation markings. In certain embodiments, a second portion of the valve retainer can include a second orientation marking, which can be aligned with a first orientation marking on the first portion of the valve retainer.

Abstract: A stent according to an embodiment of the invention includes an elongate body having a proximal end portion and a distal end portion. The elongate body defines a lumen and an opening in communication with the lumen between the proximal end portion and the distal end portion configured to enable the flow of fluid therethrough. The lumen is configured to have a diameter wherein the opening has a width greater than half the size of the diameter and less than the diameter of the lumen. The opening has a length at least twice the width of opening. In some embodiments, the opening is configured to laterally receive a guidewire therethrough. The elongate body can be configured to releasably couple the guidewire within the lumen of the elongate body such that the elongate body can be slidably moved along the guidewire.

Abstract: The present technology relates generally to a method and device for closing percutaneous punctures, and more particularly to a multi-lumen tamper for such a device. A closure device for sealing a percutaneous puncture in a wall of a body passageway is disclosed, the closure device including a plug configured to engage a surface of the puncture; a toggle configured to engage an internal surface of the body passageway; an elongate filament configured to associate the plug with the toggle; a locking member configured to engage the plug; and a tamper comprising at least two lumens, wherein a first lumen of the at least two lumens is configured to deliver a pharmaceutical agent to the plug.

Abstract: An enteral feeding system including: an enteral feeding tube, a pump configured to draw a liquid from a reservoir to the enteral feeding tube; a switching mechanism associated with at least four vacuum lumens provided with the enteral feeding tube; and a controller configured to automatically control the pump and the switching mechanism wherein controlling the pump and the switching mechanism includes coordinating the operation of the switch with the operation of the pump.

Abstract: A method and apparatus for fluid delivery enables navigation through tortuous, spatially restricted body anatomy to access narrow diameter body lumens for the continuous delivery of fluids, including therapeutic fluids, to the lumen in an atraumatic manner that avoids damage to the body lumen. The fluid delivery device can have a flexible conduit having a proximal end, a distal end, and a lumen extending along an interior of the flexible conduit providing a fluid flow path between the proximal and distal ends, where the lumen transitions into a micro-lumen exiting through a port through which a high concentration of fluid injected into the lumen exits laterally out along an image viewable zone at the distal end of the flexible conduit. The flexible conduit has a maximum outer diameter sized sufficient to navigate narrow diameter body lumens.

Abstract: A cannula assembly having a retention member and a method of manufacture of the cannula assembly is provided. The cannula assembly includes a cannula and a sleeve disposed around the cannula from a proximal end to a distal end. The sleeve can be pre-formed by a stretch blow molding process then advanced over the cannula. The sleeve includes an inflatable balloon and an annular ring distal the inflatable balloon. The cannula includes an annular recess. The annular ring is sized to have an interference fit with the annular recess.

Abstract: A vascular graft having a sealing layer and a tapered length portion. The sealing layer provides the vascular graft with low bleed characteristics subsequent to a needle puncture such as with a dialysis needle or a suture needle. The sealing layer in the tapered length portion has varying wall thickness along the tapered length portion.

Abstract: A method and device for implanting a medical lead. The device includes an elongate shaft defining a major longitudinal axis and including a proximal end and a distal end. A necked portion coupled to and extending from the distal end is included, the necked portion defines a first thickness and a substantially planar surface, the necked portion being at least resiliently movable in a direction normal to the major longitudinal axis. A tip disposed at the distal end of the necked portion is included, the tip defining a second thickness greater than the first thickness.

Abstract: A device including a catheter (14) and a medical instrument (12). The catheter includes an inner portion (16) and one or more unlocking features (18). The medical instrument includes one or more locking features (24). When the medical instrument is in the inner portion of the catheter, the one or more unlocking features engage the one or more locking features so that the medical instrument can bend in the catheter. When the medical instrument is outside the catheter, the one or more unlocking features disengage from the one or more locking features so that the medical instrument is restricted from bending.

Abstract: A metering device that improves the aseptic transfer of powder and reconstitution fluid into the metering device for medical use. In some implementations, the metering device comprises a housing, containing a metering chamber that defines a volume. The housing also has a connection portion, an extraction portion, and a metering member in fluid communication with the metering chamber. In other embodiments, the metering device additionally includes a dispensing aid that facilitates the dispensing of powder from a first container into the metering chamber through the connection portion. The connection portion is capable of insertion into a second container that contains fluid, thereby allowing a mixture of powder and fluid to form in the metering chamber. The mixture, then ready for use, is removable from the metering chamber through the extraction portion by an extraction device.

Abstract: Devices and methods can be used to treat long gap esophageal atresia, while obviating much of the delay and complexities associated with current procedures. The devices and methods involve actively stretching the esophagus portions with traction to promote growth of the esophagus portions. Moreover, the devices and methods provided allow for a compression anastomosis to occur between the esophageal ends. This eliminates the need for a second operation to suture the esophageal ends together.

Abstract: A first tube is a medical tube provided with a first portion, a second portion and a third portion in this order from the proximal end side toward the distal end side and is made of a resin. At the second portion, the outer diameter is smaller than the outer diameter of the first portion and the inner diameter is substantially equal to the inner diameter of the first portion. At the third portion, the outer diameter and the inner diameter are respectively smaller than the outer diameter and the inner diameter of the second portion. In this manner, a medical tube in which the outer diameter of the proximal end side is relatively large and the outer diameter of the distal end side is relatively small while securing the inner diameter having a sufficient size at the distal end side can be provided.

Abstract: The safety shield is comprised a one piece body, e.g. of biocompatible plastic, having a hollow stem 11 and a disc-shaped collar 13 extending radially outwardly from one end of the hollow stem 11. The safety shield is mounted by the user in friction fit manner in a hub of an implanted needle and serves as a guide for the insertion of a biopsy needle into the implanted needle.

Abstract: Systems and methods for use medical procedures including catheters and stylets are disclosed. The catheter includes a wall having an inner surface and an outer surface, the inner surface defining a lumen, and the wall defining at least one side opening from the outer surface to the inner surface. The stylet includes an elongate body defining a passage and at least one aperture in fluid communication with the passage. The stylet also includes a first blocking dam secured to the elongate body proximal to the at least one aperture and a second blocking dam secured to the elongate body distal to the at least one aperture.

Abstract: A permeation apparatus comprises an aspiration tube; an injection tube; and a water-absorbing cover member for covering at least a distal end of the injection tube and a vicinity of the distal end. The aspiration tube is configured to aspirate a fluid flowing from the water-absorbing cover member into the aspiration tube.

Abstract: A luer connection device is disclosed having a housing including a side wall having an inside surface defining a lumen with a central axis, a proximal end, and a distal end including a male luer tip having a central flow diverter extending outwardly from the central axis of the lumen to direct a fluid to a circumferential dead space distal to the male luer tip. A luer connection device is also disclosed having a flow expansion channel disposed in the lumen tapering outward from the wall of tubular housing and partially extending along a longitudinal axis from the tip opening toward the base opening for increasing mixing and flow through a circumferential dead space in the fluid path distal to the male luer tip.

Abstract: This intraocular lens (IOL) injector cartridge has a proximal opening in a main body for receiving an IOL. The main body has a lumen that extends longitudinally to a distal end having an opening smaller than the IOL. Passage through the lumen compresses or rolls the IOL so that when the distal end is inserted through a small incision in the eye the IOL can be expelled into the capsular bag. The distal end of the cartridge is beveled with a leading tip in front of a trailing heel. The characteristics of the beveled end are such that damage to the IOL is reduced. The bevel may be straight or curved and includes a distal face defined by the thickness of the distal end between the lumen and an exterior surface. The distal face may be flush with the bevel or chamfered. An inner corner angle between the distal face and the lumen is ?60° to reduce the chance of scratching the IOL as it passes out of the distal opening.

Abstract: Transradial access devices, systems, and methods. An exemplary device of the present disclosure for providing access to a vessel or other luminal organ and to prevent overperforation of the same comprises a needle having a needle tip and at least one current element positioned thereon or embedded therein at or near the needle tip, a sheath positioned around at least part of the needle, and a protractor in communication with the needle, whereby engagement of the protractor causes the needle tip to protract from the sheath through the aperture, and whereby release of the protractor causes the needle tip to retract through the aperture into the sheath. Activation of the at least one current element can facilitation vasodilation of the vessel or other luminal organ.

Abstract: Systems, apparatuses, and methods for treating native heart valves are disclosed herein. A system for delivering a prosthetic device into a heart of a patient includes an elongated catheter body and a delivery capsule. The delivery capsule can be hydraulically driven to deploy at least a portion of a prosthetic heart valve device. The delivery capsule can release the prosthetic heart valve device at a desired treatment site in a patient.

Abstract: An osteotome for sinus lift procedures includes a body interchangeable with various handles. The body includes a shaft that is releasably received into the handle, and a tip portion. The tip portion may be directly utilized for ridge expansion/bone compression, or a succession of tip members may instead be received thereon to provide suitable diameter escalation to create the socket. A conduit in the tip portion interconnects with a conduit in a hydration port and a conduit in a tip member. A hose couples the hydration port to a syringe, to deliver fluid out the tip member to lift the membrane. Graduated syringe markings permit delivery of measured fluid quantities to control the amount of lift. A second hydration port is coupled to a graduated cylinder through a valve, which is opened after lifting is complete, to measure the fluid released. A loss of fluid measured indicates a sinus tear.

Abstract: A stent is disclosed that has an elongated body composed of a bioabsorbable polymer having a proximal end, a distal end, two open spiral channels formed on the exterior surface of the body to provide fluid communication between the proximal end and the distal end. The stent also has a central lumen open at the proximal and distal ends of the stent for the passage of a guide wire. A method for using the stent and a kit containing the stent are also disclosed.

Abstract: Catheters and methods for supporting a guidewire or delivering a radiopaque, diagnostic or therapeutic agent through a vessel stenosis or other tortuous anatomy are disclosed. A catheter can comprise an elongate shaft body and a tip member disposed at a distal end of the shaft body. The shaft body can extend from a proximal end to the distal end and can define an inner lumen. The shaft body can include a liner, a braid member surrounding the liner, a multi-layer coil surrounding the braid member, and a polymer cover surrounding the multi-layer coil. An outer surface portion of the polymer cover can include one or more helical threads, which can be enveloped in an outer wrapper. The tip member can be made from a metal or a polymer. Polymer tip members can include a hard or semi-hard distal tip.

Abstract: An elongated member such as a catheter that uses ultrasound or optical coherence tomography “OCT”) technology to approximate the dimensions of a structure into which the catheter has been placed. The catheter includes multiple ultrasound transducers arranged in an annular or circumferential configuration on, embedded into or within the body of the elongated member so that distance measurements can be obtained between the elongated member and the wall of the immediately facing structure (e.g., a fluid-filled lumen). Utilizing these measurements, the present invention approximates for the physician the shape and size of the structure into which the elongated member is placed. The invention also includes a method for producing three-dimensional images from two-dimensional images.

Abstract: Disclosed are various embodiments for illuminated medical infusion including, for example, a medical infusion system which includes a source of illumination and an illuminating infusion line and wherein the illuminating infusion line includes an integrated fluid transmission channel and light transmission channel.

Abstract: A delivery system for delivering a prosthesis includes a sheath, a slide shaft having a threaded outer surface, and a handle. The handle includes an internal spring assembly for selectively engaging and disengaging the handle with the threaded outer surface of the slide shaft. The internal spring assembly includes at least one spring arm, a head coupled to the spring arm and having a circumferentially rounded threaded inner surface, and a ring slidably disposed over the spring arm. When the ring is in a first longitudinal position, the threaded inner surface of the head is spaced apart from the threaded outer surface of the slide shaft. When the ring is in a second longitudinal position, the threaded inner surface of the head is threadedly engaged with the threaded outer surface of the slide shaft. The handle may include a resilient cover to provide the internal spring assembly with a biased or nominal operational position.

Abstract: A medical device including a shaft having an elongated inner member and an elongated tubular reinforcing member disposed over at least a portion of the inner member. In some embodiments, at least a portion of the outer surface of the inner member is spaced from the inner surface of the reinforcing member, defining a space substantially free of any other structures of the device. In some embodiments, the shaft can include a tip structure disposed on a distal portion of the inner member. In some such embodiments, the reinforcing member has a distal end, and the tip structure is disposed on the distal portion of the inner member adjacent the distal end of the reinforcing member. Additionally, in some embodiments, the reinforcing member can include a plurality of apertures defined therein, for example, to enhance the flexibility or other such characteristics of all or portions of the reinforcing member.

Abstract: A bioabsorable stent is disclosed. The stent is made of a polymer and/or non-polymer material and has an elongated body having a proximate end, a distal end, and at least one open channel formed on the exterior surface of the elongated body to provide fluid communication between the proximal end and the distal end. Also disclosed is a bioabsorable stent having an elongated center rod having a proximate end and a distal end and a plurality of leaflets extending outward from the center rod and forming channels between two neighboring leaflets to provide fluid communication between the proximal end and the distal end.

Abstract: A device, system, and method for providing support to a mapping catheter during mapping or pacing and for adjusting the diameter of a distal loop portion of currently available mapping catheters. A medical device support device includes an elongate body defining a wall and an at least substantially linear proximal portion and a distal portion being transitionable between an at least substantially linear configuration and an expanded configuration, the elongate body defining a lumen extending through the proximal portion and distal portion, the lumen being entirely surrounded by the wall in the proximal portion and being partially surrounded by the wall in the distal portion. For example, the lumen may be sized to receive a mapping catheter therein such that adjustment of the configuration or diameter of the distal portion of the elongate body will likewise modify the configuration or diameter of the distal portion of the mapping catheter.

Abstract: A catheter includes a catheter shaft having an inner layer, a reinforcing body covering the inner layer, and an outer layer covering the reinforcing body. Additionally, a tubular metallic distal end tip is provided at the distal end of the catheter shaft, and a slit is formed on the distal end tip. An outer peripheral surface of the distal end tip is provided with outer coating such that the outer coating is disposed within the slit. Thus, the metallic distal end tip may bend easily and the distal end tip is not easily caught on, for example, a lesion.

Abstract: Methods and devices for adjusting or configuring the flow rate of an intraocular shunt are provided whereby hypotony can be avoided by increasing the flow rate through the device. In some embodiments, the device is a shunt that can have a first flow that can be modified to a second flow by modifying the shunt, such as by cutting the shunt. Additionally, one or more dissolvable portions can be present to provide an initial flow restriction and subsequent increase in flow over time.

Abstract: The present disclosure generally relates to a biopsy needle configured to maximize tissue sampling yield and collect a cohesive unit of sampled tissue. The biopsy needle includes an elongate tubular body comprising a lumen extending therethrough from a proximal open end to a distal open end of the body. The distal end includes first and second tip portions extending therefrom and radially opposing one another. The first tip portion has a length greater than the second tip portion, thereby resulting in an increased surface area of a curvilinear cutting edge extending from the first tip portion to the second tip portion. Additionally, each of the first and second tip portions defines a point configured to pierce the tissue to be sampled and further direct tissue towards the lumen of the body to be excised by the cutting edge upon contact therewith.

Abstract: A medical catheter includes an elongate member and an insert. The elongate member has proximal and distal end portions and defines a longitudinal axis through the proximal and distal end portions. The elongate member includes a wall at least partially defining a longitudinal lumen and defining a side opening extending radially from an outer surface of the wall to the longitudinal lumen. The insert is at least partially disposed within the side opening and at least partially defines an insert passage in fluid communication with the longitudinal lumen. The elongate member includes a first material defining the side opening and the insert includes a second material different from the first material.

Abstract: A catheter includes an elongate member (12) having a proximal end and a distal end. The distal end has at least one drainage opening (20). At least one of; the at least one drainage opening (20) is a single elongate opening, or is two circumferentially spaced elongate openings (FIG. 5), or is at least three staggered openings (FIG. 3), or is an array of staggered openings (FIG. 3). Alternatively or additionally, a sleeve member (10) is arranged on the elongate member (12) and is movable at least between a first position (FIG. 1) covering the at least one drainage opening (20) and a second position (FIG. 2) which allows fluid to pass into the catheter. A method of using the catheter includes inserting a catheter having a retractable sleeve (10) into a user's body and retracting the retractable sleeve (10) to expose drainage openings (20) and drain fluid from the body.

Abstract: The methods, systems, and devices disclosed herein generally involve convection-enhanced delivery of drugs to a target region within a patient. Microfluidic catheter devices are disclosed that are particularly suitable for targeted delivery of drugs via convection, including devices capable of multi-directional drug delivery, devices that control fluid pressure and velocity using the venturi effect, and devices that include conformable balloons. Methods of treating various diseases using such devices are also disclosed, including methods of treating cerebral and spinal cavernous malformations, cavernomas, and hemangiomas, methods of treating neurological diseases, methods of treatment using multiple microfluidic delivery devices, methods of treating hearing disorders, methods of spinal drug delivery using microfluidic devices, and methods of delivering stem cells and therapeutics during fetal surgery. Methods of manufacturing such devices are also disclosed.

Abstract: A catheter is disclosed which has at least a two-layered structure and can suppress decrease in function thereof by suppressing the disorder at an interface between layers during use, and a method for manufacturing the same. The catheter has an inner layer as a tube shaped body made of a thermoplastic resin and an outer layer, as a tube shaped body made of a thermoplastic resin, coming into contact with the outer surface of the inner layer, and has a reinforcement member which is at least partially embedded in the inner layer and includes a gap leading the inner layer toward the radial outside of the catheter. The inner layer has a protrusion which extends in an axial direction of the catheter while protruding from the gap to the radial outside, is positioned on the radial outside of the reinforcement member, and ingrows into the outer layer.

Abstract: A stent according to the present invention includes: a stent main body that has a plurality of holes formed in the surface thereof and a circumferential part of which the inside is hollow; and a cover that covers one side of the outer circumferential surface of the stent main body, in which the stent main body has an exterior path that provides a channel through which the body fluid secreted from a diverging duct can flow along the longitudinal direction of the stent main body to the outside of the cover.

Abstract: A stent is disclosed that has an elongated body having a proximal end, a distal end, at least one open spiral channel formed on the exterior surface of the body to provide fluid communication between the proximal end and the distal end. The stent also has a central lumen open at the proximal and distal ends of the stent for the passage of a guide wire. A method for using the stent and a kit containing the stent are also disclosed.

Abstract: A vascular intervention device delivery system, such as for implanting a self expanding stent, includes a thumbwheel rotatably mounted in a handle. A catheter has a proximal end attached to the handle and a distal carrier segment for mounting a stent thereon. A retractable sheath is movable to a position retracted proximally to uncover the distal carrier segment. A pull with a curved cross section extends between the thumbwheel and the retractable sheath. An idler wheel with a perimeter notch is rotatably mounted in the handle proximal to the thumbwheel. A pin is movably in the handle between a first position received in the perimeter notch to block rotation of the idler wheel, and a second position outside of the perimeter notch to permit rotation of the idler wheel. The pull wraps around the idler wheel to return in a direction for being wound onto a spool of the thumbwheel.

Abstract: A delivery system is described. The system includes an integrated shield which is used to selectively cover a needle end portion of the device.

Abstract: Sheath assembly for the insertion of a cord-shaped element (32, 105), comprising an introducer sheath (101) and an auxiliary sheath (104) for insertion into the introducer sheath (101) together with the cord-shaped element (32, 105), with first fastening means (106) for detachably fastening the auxiliary sheath to the introducer sheath, and with second fastening means (107) for detachably fastening the cord-shaped element to the auxiliary sheath, wherein the introducer sheath (101) has a first sheath housing (13, 114) and a distal tubular section (11, 41a) that terminates in the first sheath housing, and a first flushing device (108), wherein the auxiliary sheath (104) has a second sheath inner chamber (111), a distal, tubular part (112) and a second flushing device (109).

Abstract: An embodiment in accordance with the present invention provides an implanted catheter and an external device that the patient uses to inject a therapeutic into the implanted tube. The implanted catheter can be equipped with a fixation mechanism that secures the catheter in place and eases physician insertion and removal. The fixation mechanism can include shape memory arms having silicone tips or can be a second catheter branch configured to hold the device in the user's sinus cavity. The catheter can also include numerous exit holes to prevent obstruction and deliver the therapeutic. An interface between the implanted catheter and the external device is incorporated, to ensure a reliable seal for medication passage. A method and device for delivery of the catheter to the correct position can also be included.

Abstract: The present invention includes various embodiments of methods of circulating blood in a mammalian circulatory system, and various blood circulation assemblies adapted to perform such circulation.

Abstract: An elongate catheter tip may be coupled to an elongate catheter body adjacent a distal end of the catheter body. To couple a catheter tip to a catheter body, a proximal portion of the catheter tip may (1) be disposed between a first elongate member and an second elongate member and (2) be subsequently fused to the second elongate member and the first elongate member. The resulting catheter and catheter tip may, among other functions, facilitate the measurement of differences in fluid pressure and/or facilitate the delivery of fluid or medical devices during a medical procedure.

Abstract: Catheters and methods of making catheters are provided which include a connector with a guide wire channel and an inflation channel, a shaft extending from a proximal end to a distal end and having a guide wire lumen and an inflation lumen, the shaft being connected, at its proximal end, to the connector so that said guidewire lumen and inflation lumen are mechanically and fluidly connected with said guide wire channel and inflation channel respectively. The connection is realized in correspondence to a kink portion. Such catheters may include a protective sheath placed around an external wall of the shaft extending from a first sheath end, axially placed at a first distance from the proximal end of the shaft so as to allow direct contact and fixation between the external wall of the shaft and the internal wall of the kink portion, to a second sheath end.

Abstract: A vapor hydrated packaged catheter assembly and method of manufacturing and distributing same includes a gas impermeable package housing a catheter within a catheter-receiving cavity. The catheter assembly has a hydrophilic coating applied to at least a portion of the outer surface of a catheter tube or shaft which may be surrounded by a sleeve to provide a no-touch, sure grip feature. The catheter assembly is disposed within the catheter receiving cavity of the package together with a limited amount of a vapor donating liquid provided as a source of vapor to activate the hydrophilic coating. The amount of vapor donating liquid is less than the amount that would otherwise be sufficient to cause a spill hazard. It may be loose liquid as a desired percentage of the volume of a tube-receiving portion of the catheter receiving cavity of the package, or it may be contained in a liquid sequestering element.