Abstract: A device 560, for administering multiple single doses of a medicated cream, includes a cartridge 562 having a barrel 564 for containing the cream, a plunger 608 for moving the cream from within the cartridge, and a stem 610 for moving the plunger within the cartridge. A carrier 612 is formed with a cartridge-receiving nest 712 for receiving the barrel 564. A plurality of spaced, transaxial grooves 726, 728, 730 and 732 are formed in the carrier 612 for receiving a flange 572 of the cartridge 562 during the dispensing of multiple, successive, single doses of the cream. The carrier 612 is formed with a pair of resilient ears 750 and 752 and a passage 738 for removably retaining the stem 610 with the carrier while allowing axial movement of the stem.

Abstract: The present invention relates to a medicament delivery device (10) comprising a front housing (12) and a rear housing (14) connected to each other; a medicament container (18) disposed within the front housing (12), wherein the container (18) has a front opening with or for a delivery member for delivering the medicament therethrough and at least one movable stopper (25); and a compression spring (26) having a predetermined compressed length and a predetermined outer diameter, wherein the compressed length is the length of the spring when it is in a pre-tensioned state; wherein the device further comprises a first guide means comprising a front part (28) having a predetermined first length (61), a middle part (42) having a predetermined second length (62), and a rear part (34) having a predetermined third length (63), wherein said predetermined third length corresponds to the predetermined compressed length of the compression spring, wherein the front part (28) is arranged to be in contact with the movable st

Abstract: A delivery system for delivering a shear-sensitive injectable material into the body of a mammal, such as a human being, acts as a mechanical feed that continuously mixes a shear-sensitive injectable material as it delivers the shear-sensitive injectable material to a target tissue, or to a site adjacent a target tissue. In one embodiment of the invention, the delivery system comprises an injector system including a rotatable mixing member coupled to a driving system. The injector system comprises a housing defining a lumen and having an output end and a driving system connection end and includes a rotatable mixing member for coupling to the driving system and for mixing and delivering the shear-sensitive injectable material. The driving system comprises a drive mechanism, an actuator capable of actuating the drive mechanism, and an interfacing member coupled to the drive mechanism for coupling with the mixing member to rotate the mixing member when the interfacing member is driven by the drive mechanism.

Abstract: A biomaterial delivery device includes an elongated handheld powder storage conduit with proximal and distal ends and a bore having a central axis. The proximal end is closed by a movable powder dispensing actuator, and the distal end is closed by an openable sealing nib moveable from its closed to its open position by force upon the actuator whether or not the distal end is in contact with a surface. The conduit contains finely-divided loosely-filled powdered sterile biomaterial and a plurality of powder-contacting clump-disrupting projections arrayed inside and along the length of the conduit between the actuator and the nib. The projections are movable in the direction of the central axis by force upon the actuator, and the device when held upright with the nib opened provides a path along which powder may fall past the projections to be gravitationally dispensed in non-atomized form.

Abstract: An adapter for use with an appliance for administering an injectable product, the adapter serving to create a product connection between a catheter and a product container that can be inserted into the appliance, and including a thread for screwing the adapter to the appliance, a stop for fixing the container in the longitudinal direction of the thread, an attachment piece to which the catheter may be connected, and a product channel that extends through the attachment piece and the thread.

Abstract: One embodiment is directed to a method of conducting an injection, comprising: providing an assembly of a syringe plunger movably coupled to a syringe body which may contain fluid for infusion, the syringe body having a distal end that is removably coupled to a Luer adaptor, the Luer adaptor defining a needle lumen through which a needle may be coupled, the Luer adaptor comprising a distal surface configured to be removably coupled to a Luer fitting of another device; deciding upon infusion via needle injection or Luer coupling; and selectably configuring the assembly for needle injection or Luer coupling by removing the Luer adaptor to further expose the needle for needle injection, or by leaving the Luer adaptor in place and coupling it to the Luer fitting of the other device.

Abstract: A piston configured to be received within a syringe is disclosed. The piston includes a valve body defining a proximal end and a distal end, a filter disposed within the proximal end of the valve body, and a valve disk disposed within the distal end of the valve body. As the piston is advanced through the syringe, the valve disk is configured to provide fluid flow through the valve body.

Abstract: An assembly includes a dispensing syringe device configured to receive an amount of biomaterial and to dispense the biomaterial. The dispensing syringe device includes a syringe barrel for receiving the biomaterial, a discharge outlet for dispensing the biomaterial from the syringe barrel, and a plunger received in the syringe barrel. The plunger has a plunger body and a plunger passageway extending therethrough configured to receive a stylet. The assembly further includes a cannulus device configured to be coupled with the dispensing syringe device, to receive biomaterial from the dispensing syringe device, and to dispense the biomaterial. The cannulus device includes a cannulus passageway configured to receive the biomaterial and a dispensing opening configured for dispensing the biomaterial.

Abstract: Various syringe systems are disclosed. One such syringe system may include a body having a hollow lumen and a distal end, a vacuum chamber disposed within the hollow lumen of the syringe body, a first plunger connected to a distal portion of the vacuum chamber, the first plunger forming a first seal against an inner surface of the syringe body and defining a fluid delivery volume between the first plunger and the distal end of the syringe body, a second plunger disposed within the vacuum chamber, the second plunger forming a second seal against an inner surface of the vacuum chamber and defining a proximal and distal volume compartments within the vacuum chamber, and a piston affixed to the second plunger, the piston configured to move the second plunger within the vacuum chamber, thereby altering a volume of the proximal volume compartment and a volume of the distal volume compartment.

Abstract: A medication delivery device is provided which is switchable between an operational state and a resetting state and which comprises a housing having a proximal end and a distal end, a piston rod being moveable in a distal direction with respect to the housing for medication delivery, a conversion element adapted to at least partially convert a rotational movement of the piston rod into an axial movement of the piston rod, coupling means prevented from rotational movement with respect to the housing and adapted to engage with the conversion element in the operational state, a drive assembly comprising at least two drive assembly members and adapted for moving the piston rod in the distal direction, and a resilient member adapted to provide a force on the drive assembly for engagement of the drive assembly members. In the operational state of the device the coupling means is engaged with the conversion element, the conversion element thereby being prevented from rotation with respect to the housing.

Abstract: An infusion pump assembly includes a locking tab and a pump barrel inside a pump barrel housing, the pump barrel accommodates a reservoir assembly. The reservoir assembly includes a reservoir and a plunger rod. The infusion pump assembly also includes a locking disc at a terminus of the pump barrel. The locking disc includes a clearance hole for the plunger rod. The locking disc also includes at least one locking tab notch in close proximity with the locking tab. The locking tab is in moveable engagement with the locking tab notch, and the reservoir moves the locking tab from a locked position to an unlocked position when the plunger rod is inserted through clearance hole. The locking disc rotates upon torque being applied to the reservoir assembly, the locking disc rotating from a non-loaded position to a loaded position with respect to the plunger rod and a drive screw.

Abstract: An injection device has a dispensing chamber housing, a plunger, and a temperature control device. The dispensing chamber housing has a first part and a second part. The first part is thermally coupled to a needle. The second part is thermally coupled to the first part. The second part has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for holding a quantity of a substance. The plunger is engaged with an inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The temperature control device at least partially surrounds the dispensing chamber housing and is capable of altering a temperature of the substance in the dispensing chamber. The second part has a greater thermal coefficient than the first part.

Abstract: System comprising a sensor assembly (3, 4, 5, 6) adapted to measure a magnetic field, and a moveable element (1) adapted to be moved relative to the sensor assembly between two positions by a combined axial and rotational movement, the rotational movement having a pre-determined relationship to the axial movement. A magnet (3) is mounted to the moveable element and configured to generate a spatial magnetic field which relative to the sensor assembly varies corresponding to both the axial and rotational movement of the magnet and thus the moveable element. A processor is configured to determine on the basis of measured values for the magnetic field an axial position of the moveable element.

Abstract: Described is a medicament delivery device comprising a needle and a layer of a composition coupled to at least a portion of the needle. The composition has a low viscosity and a low surface tension.

Abstract: A syringe assembly includes a barrel that has a first end and a second end. Each of the first and second ends is open. A needle hub is fluidly coupled to and extends away from the second end. A plunger extends into the first end and includes an internal end positioned within the barrel and an external end positioned distal to the barrel. A longitudinal axis is defined extending through the external end and the second end. A needle is fluidly coupled to and extends away from the needle hub. A grip is attached to the plunger. The grip is engaged by a person's finger to urge the plunger into the barrel. The grip has an outward portion extending outwardly away from the plunger and away from the longitudinal axis. The outward portion extends generally toward the barrel.

Abstract: A needleless injector including a body including a fluid chamber; an outer shaft extending from an outer shaft proximal end to an outer shaft distal end, wherein the outer shaft includes an outer shaft lumen to accommodate an injection shaft; an injection shaft located within the outer shaft lumen and moveable lengthwise and/or rotationally within the outer shaft lumen, wherein the injection shaft includes an injection shaft proximal end, an injection shaft distal end, an injection shaft terminus, and an injection lumen. The injector further includes an injection orifice at the distal end of the injection shaft and in fluid communication with the fluid chamber through the injection lumen; a pressure source in communication with the fluid chamber; and an optical device that allows viewing a location at a distal end of the device.

Abstract: Bent syringes, mounting systems for bent syringes, and devices incorporating bent syringes are described herein. The syringes include a bent cylindrical body bent about a radius and a plunger bent about the radius of the bent cylindrical body and configured and arranged to be received by the proximal open end of the bent cylindrical body and movably disposed within at least a portion of the bent cylindrical body.

Abstract: An autoinjector includes front and rear separable housing parts 10, 12. These are connected by a rotary coupling action such as by bayonet coupling and the relative rotation action turns a needle shield 20 from a locked position in which it is both locked against longitudinal movement and acts as a shutter obscuring the contents of the syringe to an open position where the contents of the syringe are visible and the shield portion is freed for longitudinal movement. Connecting and securing the rear portion 12 on the front portion 11 therefore unlocks the needle shield 20 for operation. On completion of an injection, uncoupling of the front and rear portions returns the needle shield 20 to its locked position so the front portion may be disposed of safely.

Abstract: An injector (10) for injecting a medicament into a patient. The injector includes a container (18) defining a first chamber (22), which contains a fluid therein, and a second chamber (23). The injector also includes an injection conduit (126) configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source (62) is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.

Abstract: A syringe assembly includes a syringe barrel having an inside surface defining a chamber, an open proximal end, a distal end, and an outlet; a plunger assembly disposed at least partially within the syringe barrel, including an elongate plunger rod having a locking flange formed thereon; and a plunger head having a distal sealing surface, the plunger rod being engageable with the plunger head such that the plunger rod is adapted to move the plunger head within the chamber of the syringe barrel through an injection cycle; and a flange lock disposed at the open proximal end of the barrel. The flange lock is integral with the open proximal end of the syringe barrel. During the injection cycle, the flange lock engages the locking flange of the plunger rod so as to prevent removal of the plunger rod from the syringe barrel.

Abstract: There are provided a needle-equipped syringe barrel and a needle-equipped syringe in which a needle is suitably fixed to a syringe nozzle, and a mold and a method for molding thereof. A metal needle 12 is integrally equipped to a synthetic resin syringe nozzle 113 by integral molding, an area where the needle 12 comes into contact with the nozzle 113 being in a range of 11 to 50 mm2. A needle-equipped syringe barrel 1 in which a metal needle 12 is integrally equipped to a synthetic resin syringe nozzle 113 by integral molding, height of a needle end 122 extruded toward an inner hollow portion thereof opposite to a needle head 121 being in a range of 0.4 to 11 mm.

Abstract: The present invention relates to a method and to a monitoring device for monitoring operation of a drug delivery device, the monitoring device comprising of at least a first and a second sensor arranged at a distance from each other with regard to a first direction and being adapted to generate a first and a second electrical signal in response to an operation of the device, a processing unit configured to determine a time delay between the first and the second electrical signals and being adapted to determine at least one state parameter of the drug delivery device on the basis of said time delay.

Abstract: Syringe assemblies comprising a disinfecting reservoir collar to ensure adherence to aseptic techniques for use in flush procedures for vascular access devices (VAD's) are described. The syringe assemblies include a plunger rod, a syringe barrel, and reservoir collar that permits disinfection of a hub of a VAD connector upon connection to the reservoir collar. Also described are methods of disinfecting vascular access devices.

Abstract: Medicament delivery device comprising: a first housing part (12) having a container holder (14) into which a medicament container (16) can be placed and wherein the container has a front opening with or for a delivery member for delivering the medicament therethrough and a movable stopper (17); a second housing part (38) arranged to be moved between a closed position and an open position in relation to said first housing part (12); a plunger rod (48) having a front end and a rear end, and wherein said plunger rod is arranged parallel beside said container holder when the second housing part is in its closed position; wherein the second housing part comprises resiliently displacement means (50, 52) wherein one of the resiliently displacement means (50) is fixedly connected to said plunger rod, such that when said second housing part (38) is moved from its closed position to its open position, the plunger rod (48) is moved by said resiliently displacement means into a position where the front end of the plunger

Abstract: A retractable safety syringe includes a retractable needle hub holding a needle and having a first guiding means; and a hollow barrel having a second guiding means set correspondingly to the first guiding means; and a collapsible plunger comprising of a first plunger element having a protrusion releasably coupled with a second plunger element having a longitudinal slot with a pinched zone to curb the movement of said protrusion; and a spring disposed between the needle hub and hollow barrel and acts between the needle hub and the hollow barrel. The uncoupling of the collapsible plunger triggers the retraction mechanism to enable the needle hub to retract into the barrel by the decompression force of a spring. The reliability of retraction is further improved by a longitudinal slot and a protrusion to facilitate the retreating of the collapsible plunger in an orderly way.

Abstract: A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with at least first and second tracks together forming an encoder, each track comprising conductive segments and non-conductive segments; and at least first and second groups of contacts configured to engage the first and second tracks respectively at predetermined intervals along the length of the track.

Abstract: A method and system for delivering a user-settable dose of a first medicament and a non-user settable dose of a second medicament through a single dose setter and a single dispense interface. The drug delivery system includes a drug delivery device and a medicated module. The drug delivery device comprises a single dose setter operably connected to a primary reservoir containing the first medicament. The medicated module comprises (i) a collapsible feature holding the second medicament and (ii) the single dispense interface having an output needle. Further, the drug delivery device and medicated module are each configured such that the single dose setter is mechanically linked to the collapsible feature after attachment of the medicated module to the drug delivery device.

Abstract: A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.

Abstract: A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with a track comprising a sequence of encoded images; and a sensor directed at the track of the cylindrical member and configured to detect features of the encoded images.

Abstract: An autoinjector comprising an outer housing in which can be mounted a syringe for holding a volume of medicament, the syringe for holding medicament having a needle at one end thereof, a syringe holder for supporting the syringe in an axial position relative to the outer housing, and an intermediate housing at least part of which is located within said outer housing, characterised in that said intermediate housing is provided with a blocking means capable of abutting the syringe or the syringe holder so as to be capable of preventing forward axial movement of the syringe when a forward axial force is applied to said needle before actuation of the autoinjector to deliver an injection, but incapable of preventing forward axial movement of the syringe during actuation of the autoinjector to deliver an injection.

Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.

Abstract: A plunger rod adapted for attachment with a stopper for use with a syringe barrel is disclosed. The plunger rod includes an elongated member having a front end and a back end, the plunger rod extending along a longitudinal axis. The plunger rod includes at least one deflecting arm associated with the front end of the elongated member. The deflecting arm is capable of deflecting radially inward during insertion of the plunger rod into a stopper, and deflecting outward into contact with an inner surface of the stopper after insertion to lock the plunger rod within the stopper.

Abstract: A cartridge holder for a drug delivery device is presented comprising a housing extending in an axial direction and being adapted to receive a cartridge at least partially filled with a medicament, said cartridge being sealed near a distal end by way of a pierceable seal. At least one bearing element is fixed to the housing, and at least one tensioning member is engaged with the bearing element and with the cartridge in an axial direction for transmitting a distally directed injection force from the cartridge to the housing.

Abstract: A drug capsule and a method for making a drug capsule for a drug delivery device, such as an auto injector or needle-free injector, with improved stability and container closure integrity. The injector comprises a drug capsule sealed by a piston fabricated from PTFE modified by the inclusion of a co-polymer of PPVE, preferably in an amount less than 1% by weight, resulting in better performance while the device is stored and subjected to temperature cycling.

Abstract: A method for delivering a substance to bone includes placing a stabilizing wire in a bone, creating a hole in the bone around the stabilizing wire, and providing a multichannel cannula. The multichannel cannula includes a first channel having an open proximal end and distal end, the first channel being configured to receive the stabilizing wire, and a second channel having an inlet portal and an exit portal that are in fluid communication. The cannula further includes a cap having a delivery port in fluid communication with the inlet portal and a channel for receiving the cannula therein, and a distal tip.

Abstract: An injection syringe, having a syringe cylinder, a plunger rod inserted therein and connected to a stopper by way of a coupling part, and a module that is provided in the proximal end of the syringe cylinder and having a cannula, mounted in a cannula holder received in a guided sleeve, and a sealing insert for the fluid-tight closure of the proximal end of the syringe cylinder and a protection cap for protecting the cannula, wherein the protective cap on the inner circumference has ribs extending in an axial direction, which engage in corresponding grooves of the driving part for a rotary drive thereof, and wherein in the sealing insert a hollow space is formed, which is closed on the proximal side and on the distal side transitions into an opening, by way of which a tip of the coupling part can be coupled to the hollow space.

Abstract: The present invention relates to a security syringe comprising a hollow cylinder (1) with a pair of wings (11) and a tip (12), which houses: the injection mechanism (3), a piston (2), and an injection mechanism (3) with a needle (31), a spring (32) and a membrane (33). The piston (2) has a serrated crown in the lower part (21) thereof where a chamber seal exists (22) and breaks only with the interior point of the needle (31), having the ends of the piston (2) of an inferior disk (24) and a superior disk (25) that steadies the piston (2) inside the cylinder (1). Around the cylinder (1) there is a protective funnel (13) against accidental injections. The piston comprises a cap (26) which guarantees the hermeticity of the empty chamber.

Abstract: The end face of a cylinder-piston unit has a press-in area, engaging around the mouth, and a press-on area, surrounding the press-in area. The press-in area comprises an inner web, delimiting the mouth, and an outer web. The webs delimit a recess, which surrounds the inner web and of which the depth measured parallel to the center axis of the cylinder-piston unit is at least a quarter of its width in a plane oriented normal thereto. The press-on area, at least during an injection, is offset counter to the injection direction relative to the end face of the press-in area. Moreover, the surface of the press-on area projected into a plane normal to the center axis is at least as large as the surface of the press-in area projected into the same plane.

Abstract: A medical delivery system (100) having a container (102) and a dosing assembly (104), and wherein one of the container and the dosing assembly comprises a rotatable element (106) adapted to engage the other one of the container and the dosing assembly. A container suitable for use in said medical delivery system. A dosing assembly suitable for use in said medical delivery system.

Abstract: A device for delivering medicament includes a guide nut with guide ledges which cooperate with longitudinal grooves of a plunger rod for providing a rotational lock but allowing longitudinal movement of the plunger rod in relation to the guide nut that is rotationally locked to a distal housing part by engagement devices when the distal housing part and a proximal housing part are connected to each other. The device further includes a pressure release mechanism that includes slanting wedge-like surfaces arranged on the drive nut and slanting wedge-like surfaces arranged on a fixed inner annular surface of the distal housing part, which slanting wedge-like surfaces abut each other such that they move out of contact near the end of delivery of a predetermined quantity of medicament when the drive nut is rotated.

Abstract: A syringe device includes a syringe barrel and piston having a fluid passageway extending from a vial port. Another syringe device includes a syringe barrel, a piston sleeve and an insert. A channel extends along a side of the insert. A valve controls fluid communication between the channel and the syringe barrel. Another syringe device has a syringe barrel, a piston sleeve and an insert. A valve controls fluid communication between a compartment within the insert and the syringe barrel. A method of preparing a medication includes providing a component within a syringe barrel and another component within a compartment of a piston insert. A seal is over-molded onto a tip of the insert and an end of a piston sleeve. The sleeve is rotated relative to the insert to establish fluid communication between the compartment and the barrel chamber.

Abstract: The invention provides a syringe or autoinjector for dispensing a drug comprising a rigid syringe body containing the drug, an oxygen absorbing material, a separating element between the drug and oxygen absorbing material to prevent the drug from contacting the oxygen absorbing material but which allows oxygen to pass from the drug to the oxygen absorbing material, and an oxygen impermeable container enclosing both the drug and the oxygen absorbing material, wherein the oxygen impermeable container partially or fully forms the rigid syringe body or is held within the rigid syringe body.

Abstract: A modular administration appliance including a reusable base unit and a replaceable cartridge detachably connected to the base unit and including a container for a substance and a rotatable transmission element, the base unit including a drive device by which a rotary movement is transmitted between the base unit and the cartridge, and a driving element displaceable in a rotary movement about a rotational axis by the drive device, wherein a rotation of the transmission element causes the ejection of at least a portion of the substance from the container. In some embodiments, the transmission element at least partially surrounds the drive device, and/or the drive element and the transmission element are detachably connectable to each other for transmitting the rotational movement.

Abstract: A medication injector apparatus such as an injection pen. The injection pen may include a doseable quantity identifier that uses a rotational matrix and a sensor for electrically sensing the arrangement of the dose setting mechanism of the the pen, which identifier may be part of a therapeutic dose indicating system that utilizes a cartridge recognizer to recognize a concentration of medication so as to allow an automatic determination of a therapeutic dose.

Abstract: A hand-held syringe includes a handle configured for suspending and using the syringe with a single hand. The handle includes pivotally connected first and second members. The members of the handle may be pivotally connected at intermediate positions along the lengths thereof or at or near ends thereof. The first member is associated with, and may be pivotally connected to, a syringe barrel, while the second member is associated with, and may be pivotally connected to, a syringe plunger. The syringe may be configured for a single-use (i.e., it may be disposable). Applications of use and methods of using a hand-held syringe are also disclosed.

Abstract: A cartridge holder for retaining a cartridge comprising a distal end and a proximal end being spaced apart from one another in the direction of an axis, an interior which is suitable to receive and retain a cartridge in a cartridge retaining section of the interior, and a main part and at least one protrusion which is moveably connected to the main part. The protrusion is arranged to define the radial extension of a subsection of the interior, wherein the subsection is arranged at an axial position which is further away from the distal end than the cartridge retaining section. Furthermore, the protrusion is arranged to vary the radial extension of the subsection when the protrusion is moved with respect to the main part. Moreover, a method for securing a cartridge in a cartridge holder is proposed.

Abstract: A dispensing device for use with a beneficial agent has a dispensing package, a dispenser disposed on an end portion of the dispensing package, and an actuator movably disposed along at least a portion of the package between a pre-dispensing state and a dispensing state. One arrangement also provides a beneficial agent dispenser having a dispensing port, an elongate portion and a plunger that is movably disposed relative to a tubular wall of the elongate portion during a dispensing stroke to partially penetrate a separable barrier and expel the beneficial agent through the dispensing port.

Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.

Abstract: Syringe (1) including a cylinder (2) and a piston (4), in which the outlet end (6) of the cylinder (2) is integrated with a valve male luer lock connector (7).

Abstract: A syringe assembly having a collapsible or pivotable plunger rod with magnification properties is provided. In a pre-use or packaged state, the plunger rod is positioned substantially parallel to a barrel of the syringe assembly resulting in the syringe assembly having a reduced length and a smaller packaging footprint. The smaller packaging footprint allows for reduced storage space of the syringe assembly. Upon removal from a packaging and/or a storage space, the plunger rod can be slid or pivoted toward a proximal end of the syringe barrel and locked into place such that the syringe assembly is ready for use. The plunger rod can be shaped to provide magnification to indicia of the syringe barrel and/or contents. Alternatively, a separate magnification member can be associated with the plunger rod and/or secured about the syringe barrel.