Abstract: Various embodiments of methods and systems for improving and enhancing vision are disclosed. Adjustable lenses or optical systems may be used to provide adaptive vision modification. In some embodiments, vision modification may be responsive to the current state of the user's visual system. Certain embodiments provide correction of the subject's near and far vision. Other embodiments provide enhancement of vision beyond the physiological ranges of focal length or magnification.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

Abstract: Various embodiments of methods and systems for improving and enhancing vision are disclosed. Adjustable lenses or optical systems may be used to provide adaptive vision modification. In some embodiments, vision modification may be responsive to the current state of the user's visual system. Certain embodiments provide correction of the subject's near and far vision. Other embodiments provide enhancement of vision beyond the physiological ranges of focal length or magnification.

Abstract: An ophthalmic apparatus comprises: aberration correction unit arranged to correct aberration of at least one of irradiating light directed to an eye to be examined and return light from the eye; light-receiving unit arranged to receive, as return light from the eye, the light whose aberration is corrected by the aberration correction unit and then which irradiates the eye; measurement unit arranged to measure the aberration of the return light; and control unit arranged to control the aberration correction unit based on a measurement result obtained by the measurement unit and a light reception result obtained by the light-receiving unit.

Abstract: Example embodiments include a dynamic wavefront sensor, a controllable wavefront offsetting element and a controller that controls the controllable wavefront offsetting element to offset selected non-plane wave aberration components in order to allow remaining non-plane wave aberration components to be more efficiently detected and measured.

Abstract: A fundus camera includes an optical path splitting unit arranged between a focusing unit and an imaging unit. The splitting unit has characteristics adapted to reflect light of a visible light region and to transmit near-infrared light. The splitting unit retreats from an optical path when a still fundus image is photographed. A quick-return mirror having such characteristics is used as the splitting unit. When near-infrared illumination light having a wavelength of about 850 nm is used, such light can be incident upon the imaging unit without loss of the amount of light. Visible light output from an internal fixation target is projected onto a subject's eye. A cornea diaphragm and a crystalline lens diaphragm are used for observing a fundus with invisible light. Each of the cornea diaphragm and crystalline lens diaphragm can be changed to another one having a different diameter.

Abstract: Computer-implemented systems and methods create a user environment tailored to a user's computer abilities. A series of baseline tests are administered to new users for accumulating user metric data, and a database collects and stores the user metrics. Program logic is responsive to data from the data base, where the program logic is programmed to adapt the user environment to correspond to abilities measured through the baseline tests. The program logic is further programmed to adapt user interface controls to compensate for user dexterity abilities.

Abstract: A fundus oculi observation device 1 can form a near-infrared motion image and a color image (still image) of a fundus oculi Ef. The device 1 specifies an image region within the near-infrared motion image corresponding to a region of interest within the color image while the near-infrared motion image is being formed. The device 1 scans with a signal light LS based on the specified image region, thereby forming a tomographic image along the scanning line. According to the device 1, it is possible to determine a region of interest within a still image having a comparatively high image quality, specify the image region within the motion image corresponding to this region of interest, set a measurement site for the tomographic image.

Abstract: Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a TFLT.

Abstract: An apparatus for measuring a subject's eye having an instrument axis, comprising a slit projector for projecting slits of light, at least one sensor. The apparatus being adapted to form a first image of light from a first slit on the at least one sensor after the light scatters from the eye along a first pathway. The apparatus adapted to form a second image of light from the first slit on the at least one sensor after the light scatters from the eye along a second pathway. The apparatus comprising a processor operatively coupled to receive the first image and the second image, the processor adapted to perform a projective transformation of the second image and to combine data from the first image and the second image, after it is transformed, to form a third image.

Abstract: A method for diagnosing a disease state in a subject, including examining the subject's eyes in order to determine whether the subject exhibits one or more symptoms of the disease state. Symptoms of the disease state include altered ocular characteristics, such as pupil size, pupil motility, ocular blood vessel coloration, and strobe light cutoff frequency. By evaluating changes to ocular characteristics, a disease state can be diagnosed in a subject. In addition, the severity of the disease state also can be determined.

Abstract: A non-contact ultrasonic tonometer for measuring intraocular pressure of an examinee's eye, in non-contact manner by use of an ultrasonic wave comprises: a probe including a vibrator for making the ultrasonic wave incident on the examinee's eye and a sensor for detecting the ultrasonic wave reflected from the examinee's eye; and an observation optical system for observing an anterior segment of the eye, wherein the probe is placed in an optical path of the observation optical system, and the observation optical system forms an image of the anterior segment through a surrounding region of the probe.

Abstract: A non-contact ultrasonic tonometer for measuring intraocular pressure of an examinee's eye in non-contact manner by use of an ultrasonic wave comprises: a probe including a vibrator for making the ultrasonic wave incident on the eye and a sensor for detecting the ultrasonic wave reflected from the eye; a detection unit which detects an alignment state of the probe with respect to the eye; a determination unit which determines whether the alignment state is proper or not based on a detection result of the detection unit; a trigger signal generation unit which generates a trigger signal to start measurement based on a determination result of the determination unit; and a control unit which controls the probe to emit the ultrasonic wave based on generation of the trigger signal.

Abstract: A system and method for ocular surgery includes a delivery system for generating and guiding a surgical laser beam to a focal point in a treatment area of an eye. Additionally, a contact device is employed for using the eye to establish a reference datum. Further, an optical detector is coupled to the beam path of the surgical laser to create a sequence of cross-sectional images. Each image visualizes both the reference datum and the focal point. Operationally, a computer then uses these images to position and move the focal point in the treatment area relative to the reference datum for surgery.

Abstract: A phase modulation device implemented in an ophthalmic instrument using a main light beam interacting with an eye, the device including: an apparatus for modulating the phase of the wave front of the main light beam, a controller for controlling the phase modulation apparatus following a modulation instruction, and an analyzer for analyzing the thus-performed modulation of the phase of the wave front of the main light beam, further including emitting a secondary light beam, an apparatus for directing the secondary light beam along an optical path to the modulation apparatus, then to the analyzer, and in that the optical path does not pass through the eye, and in that the controller and the analyzer receiving the modulated secondary light beam cooperate, during a stage called a learning stage, to supply data regarding the response of the phase modulation apparatus to a set of predetermined modulation instructions.

Abstract: Methods for diagnosis and treatment are provided for a patient having processing difficulties, integration problems, imbalances or abnormal postures. In one embodiment, a patient is identified having retinal signal problems creating at least one negative medical condition. Then, at least a portion of the patient's lacrimal drainage system is blocked or altered. Further, as a result of the diagnosis and treatment, the patient achieves improved retinal signal processing and at least one of the patient's negative medical conditions is improved. Other embodiments include using in combination the Z-Bell Test and/or light blocking or altering devices for diagnosis and treatment.

Abstract: In general, in some embodiments, the disclosure provides a method that includes making a subjective refraction of a person to determine information about the person's vision, making a wavefront measurement of one or both of the person's eyes to determine information about the optical properties of one or both of the person's eyes (e.g., aberrations), calculating a prescription for the person based on the information about the person's vision and the information about the optical properties of one or both of the person's eyes, and outputting the prescription.

Abstract: An eye refractive power measurement apparatus measures both eye refractive powers in cases where a pupil is small and large in diameter with ease. This apparatus includes: a measuring optical system causing an imaging device to capture a ring-shaped image based on measurement light reflected from a fundus of an examinee's eye; a light deflecting member arranged at a position, which is not conjugated with a pupil of the examinee's eye, on an optical path of the measuring optical system; a rotor causing the light deflecting member to rotate about an optical axis of the measuring optical system; and an eccentricity amount changer changing an amount of eccentricity of the measurement light, which is rotated eccentrically on a surface of the pupil, with respect to a center of the pupil, in order to change a region, where the measurement light passes, on the surface of the pupil.

Abstract: Disclosed are method and apparatus for mapping retinal thickness values to a movable measurement grid. A three-dimensional volume dataset acquired from three-dimensional optical coherence tomography is registered to a fundus image by rendering a two-dimensional composite image from the three-dimensional volume dataset and superimposing characteristic features in the two-dimensional composite image upon corresponding characteristic features in the fundus image. A measurement grid is displayed on the two-dimensional composite image. The measurement grid is moved to a region of interest, and retinal thickness values in the region of interest are mapped to sectors within the measurement grid.

Abstract: A cornea shape measurement apparatus outputs data useful for prescription as well as injection and installation of a TORIC-IOL. This apparatus includes: a projecting optical system projecting an index for measurement onto a cornea; an illuminating optical system illuminating an anterior segment on which a reference mark is placed; an imaging optical system capturing an anterior segment image containing the reference mark and an image of the index reflected from the cornea; an image processor overlaying an astigmatic axis mark indicating a direction of an astigmatic axis of the cornea, which is calculated based on the index image, on the anterior segment image; and a controller displaying the anterior segment image, which contains the astigmatic axis mark, on a display.

Abstract: Embodiments of the present invention provide methods for finding the lateral position of the fovea in an OCT image volume. In one instance, a cost function is developed whose minimum is located at or near the foveal center. This cost function includes one or more measures of retinal layer thickness and/or measures of distance from blood vessels or a priori locations.

Abstract: An ophthalmological measuring device for determining geometric structures in an eye includes an optical, triangulating measurement system for determining at least one geometric reference in the eye by triangulation, and an optical, interferometric measurement system for determining geometric detailed structures in the eye by optical interferometry. The measuring device is designed to position the geometric detailed structures determined by the interferometric measurement system on the basis of the at least one geometric reference in the eye determined by the triangulating measurement system.

Abstract: A docking method for an ophthalmic system may include the steps of aligning a docking unit of the ophthalmic system and an eye; generating an image of an internal structure of the eye by an imaging system; improving an alignment of the docking unit with the internal structure of the eye in relation to the generated image; and docking the docking unit to the eye. The generating the image step may include computing scanning data by a processor corresponding to a scanning pattern; storing the scanning data in a data buffer; transferring the scanning data by the data buffer to an output module; outputting scanning signals by the output module to one or more scanners based on the scanning data; and scanning an imaging beam with the one or more scanners according to the scanning signals.

Abstract: The following is a method to represent images for dissociative stereoscopic vision, which allows, by means of some simple operations on stereoscopic images, to develop a device comprising a processing card and LCD shuttering goggles, which together with a computer equipped with a graphic card with LVDS output and any image display device, enable to perform visual acuity tests on patients.

Abstract: Disclosed herein is a method of producing a stimulus for electrophysiological assessment of a visual field. The method comprises the steps of: generating a pseudorandom sequence of elements selected from at least two different element types, wherein elements of the sequence are assigned equal time intervals; and displaying the pseudorandom sequence. Each element of a first element type is associated with a baseline value, the baseline value being constant throughout a respective assigned time interval. Each time interval assigned to an element of a second element type is divided into a plurality of portions, each successive portion being associated with a display value of the element, wherein display values associated with, adjacent portions differ from one another, and further wherein display values associated with at least two of the portions are different from the baseline value.

Abstract: An apparatus that can measure images of at least a portion of an eye and record data sets indicative of a neurological condition. A method interrelates an image and a data set to provide an interpretive result. The apparatus and method thereby provide guidance as to the presence of a medical condition in a patient. The apparatus and method can be used in an iterative measurement process, in which the apparatus attempts to discern normal health from a state of health that is not normal health. If the interpretive result is consistent with normal health, the process terminates, information is recorded, and an optional report is given. If the interpretive result is not consistent with normal health, the apparatus and method attempts to distinguish which condition is consistent with the data and images used, and can iterate with additional measurements and information to attempt to provide a useful interpretive result.

Abstract: Implantation of an accommodating intraocular lens in an eye may require the accurate measurement of the size, circumference, or diameter of the capsular bag of the eye. A flexible ring or ring portion may be temporarily or permanently inserted into the capsular bag for measuring the circumference of the capsular bag, for example, after extraction of a natural lens from the capsular bag. The ring or ring portion is generally compressible to fit through a surgical incision, then expands to fill the capsular bag along an equatorial region. The ring or ring portion includes a central component that changes shape and/or angle as the ring or ring portion is compressed. The shape change is generally correlated to the size of the capsular bag and may be visually measured through the cornea, the measurement being generally independent of corneal magnification. The measurement may be used to determine or calculate information about the capsular bag such as its size, elasticity, accommodative range, and so forth.

Abstract: A device for the interferometric measurement of a sample, in particular the eye, including an interferometer arrangement with a first measurement beam path, through which a measurement beam falls onto the sample, and a first reference beam path, through which a reference beam runs, which is applied to the measuring beam for interference. The interferometer arrangement includes a second measuring beam path and/or second reference beam path. The optical path lengths of the second measuring beam path and/or second reference beam path are different from one of the first beam paths. The wave length difference is selected according to a distance of two measuring areas which are arranged at a distance in the depth direction of the sample.

Abstract: A vision testing system and method to assess vision function. In one embodiment, the vision testing system comprises: (1) a display; (2) a computer coupled to the display and configured to provide dynamic images, each including a substantially constant fixed point of fixation; and (3) a human input device coupled to the computer, wherein responses from a test subject are fed back to the computer to assess the test subject's vision function.

Abstract: A method of making corrective eyeglasses is disclosed. One embodiment is a method of making corrective eyeglasses. The method includes obtaining vision parameters of a patient's eyes, obtaining an eyeglass frame comprising at least one mounted optical element, and programming the optical element to define a pattern of refraction that is associated with the vision parameters.

Abstract: A device for vision testing comprises a viewing position (6) and an image surface (5). The distance between the viewing position (6) and the image surface (5) is enclosed. The relation between the resolution of the image surface and the distance between the viewing position (6) and the image surface (5) is such that the angle of a point on the image surface (5) is less than or equal to 1 minute of arc seen from the viewing position (6).

Abstract: A combination includes an OCT system, an optical instrument, optics defining an optical path from the optical instrument to a target, and secondary optics for coupling the OCT system to the optical path. This combination permits simultaneous operation of the OCT system and the optical instrument.

Abstract: Methods, devices, and systems for predicting an optical acuity measure of an optical system of an eye. An optical acuity measure can be predicted by determining a point spread function based on a wavefront measurement of an eye, convolving a resolution target with the point spread function to produce an image, and predicting the optical acuity measure of the optical system of the eye based on the image.

Abstract: A fundus imaging apparatus comprises: an irradiation optical system comprising a light source which emits a laser beam and a scanner which two-dimensionally scans the laser beam on a fundus of an examinee's eye, the irradiation optical system being adapted to focus the laser beam emitted from the light source on the fundus to form a confocal region; an imaging optical system comprising a photo-receiving element which receives reflection light of the laser beam reflected from the fundus, the imaging optical system being adapted to focus the reflection light from the fundus and receive the reflection light by the photo-receiving element; and a beam restriction member placed in an optical path of the imaging optical system, the beam restriction member comprising: one of an opening through which part of the reflection light from the fundus outside the confocal region is allowed to pass toward the photo-receiving element and a mirror part which reflects the part of the reflection light from the fundus outside the

Abstract: Upon detecting a selection of an examination start button, a start and completion management unit starts an examination. The control unit switches an observation state to an infrared light observation by an observation switching unit. Next, an examiner performs alignment while observing an eye to be examined, and photographs the eye to be examined with a photographing unit. The start and completion management unit determines whether the examination is completed according to a selection of an examination complete button, and repeats the alignment until it is determined that the examination is completed.

Abstract: The present invention provides methods, systems and software for scaling optical aberration measurements of optical systems. In one embodiment, the present invention provides a method of reconstructing optical tissues of an eye. The method comprises transmitting an image through the optical tissues of the eye. Aberration data from the transmitted image is measured across the optical tissues of the eye at a first plane. A conversion algorithm is applied to the data, converting it to corrective optical power data that can be used as a basis for constructing a treatment for the eye at a second plane.

Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.

Abstract: The invention proposes a manual measuring appliance (112) and an analytical measuring system (110) which can be used to measure at least one analyte in an eye fluid of an eye (114). The handheld measuring appliance (112) comprises a measuring system (120) and a positioning system (122). The measuring system (120) can measure at least one property of the at least one analyte and/or at least one analyte-dependent change of property of at least one ocular sensor (116) in the eye fluid, and this can be used to infer a concentration of the analyte in the eye fluid. The positioning system (122) is set up to measure a spatial positioning, wherein the spatial positioning comprises a distance between at least one measurement location in the eye (114) and the handheld measuring appliance (112) and also furthermore at least one further positioning co-ordinate.

Abstract: A method of customizing vision correction including measuring optical aberration data of a patient's eye and calculating a lens definition based on the optical aberration data, wherein calculating the lens definition comprises calculating a correction of at least one low order aberration and at least one high order aberration and is based at least partly on the patient's pupil size.

Abstract: A wavefront sensor is integrated with a surgical microscope for allowing a doctor to make repeated wavefront measurements of a patient's eye while the patient remains on an operating table in the surgical position. The device includes a wavefront sensor optically aligned with a surgical microscope such that their fields of view at least partially overlap. The inclusion of lightweight, compact diffractive optical components in the wavefront sensor allows the integrated device to be supported on a balancing mechanism above a patient's head during a surgical procedure. As a result, the need to reposition the device and/or the patient between measuring optical properties of the eye and performing surgical procedures on the eye is eliminated. Many surgical procedures may be improved or enhanced using the integrated device, including but not limited to cataract surgery, Conductive Keratoplasty, Lasik surgery, and corneal corrective surgery.

Abstract: A device for calibrating retinoscopes for diverging and/or converging streak and spot retinoscopy and a method for calibrating retinoscopes to produce a given convergence or divergence of light emitted from the retinoscope from a fixed retinoscopic working distance to produce a predetermined pupillary reflex endpoint at neutralization of a refractive error, thereby resulting in a more accurate corrective eye prescriptions and evaluation of the visual system.

Abstract: A method of creating a statistical model for use in predicting vision correction prescriptions for patients is disclosed. The method comprises obtaining a plurality of wavefront aberration measurements from a plurality of patient's eyes, obtaining a plurality of visual acuity measurements from the plurality of patients, applying values associated with the plurality of wavefront measurements to an input layer of a statistical model, applying values associated with the plurality of visual acuity measurements to an output layer of the statistical model, and generating a plurality of weight values associated with respective nodes of the statistical model based on the applied values associated with the plurality of wavefront measurements and corresponding values associated with the plurality of visual acuity measurements.

Abstract: An optical observation instrument, in particular a spectacle, a reading aid or a telescope, comprises an optical element, in particular a spectacle lens, adapted to be controllably adjustable in its refractive power, a sensor, and a control unit for adjusting the refractive power as a function of signals from the sensor. The sensor is a brightness sensor. In a method of controllably adjusting a refractive power of an optical element in an optical observation instrument an optical parameter is captured by means of a sensor and the refractive power is adjusted as a function of a signal from the sensor. By means of the sensor the brightness of the light impinging on the optical instrument is captured.

Abstract: A schematic eye used for the evaluation of the optical system of an optical coherence tomography apparatus which captures a tomogram of the fundus includes the first optical member which irradiated light from the optical system strikes and the second optical member which irradiated light from the first optical member strikes. A plurality of layers having different scattering intensities in the incident direction of irradiated light are formed on the second optical member.

Abstract: An electronic device. The device comprises circuitry for capturing data representing an image and circuitry for detecting a wireless signal associated with an object. The device also comprises circuitry, responsive to the detecting circuitry, for storing image data from said circuitry for capturing and associating and storing, with same image data, additional data included in the wireless signal.

Abstract: An apparatus for imaging an eye includes a housing and a system of optical components disposed in the housing. The apparatus is capable of operating in a line scanning laser ophthalmoscope (LSLO) mode and an optical coherence tomography (OCT) mode. The system of optical components can include a first source to provide a first beam of light for the OCT mode and a second source to provide a second beam of light for the LSLO mode. In the OCT mode, a first optic is used that (i) scans, using a first surface of the first optic, the first beam of light along a retina of an eye in a first dimension, and (ii) descans, using the first surface, a first light returning from the eye in the first dimension to a detection system in the OCT mode. In the LSLO mode, the first optic is used where the second beam of light passes through a second surface of the first optic.

Abstract: An apparatus for determining spherical and cylinder components of subjective refraction of a patient's vision includes a wavefront measurement device that can produce a measure of quality of vision in a return beam from the patient's eye viewing a target through a corrective test lens in the apparatus. The corrective lenses may be varied and a plurality of measurements of quality of vision may be obtained and analyzed to determine the spherical and cylinder components. Accordingly, the eye examiner may conduct a refraction examination without a subjective response from the patient.

Abstract: The present invention relates to a system and a method for determining the power of an artificial intraocular lens (IOL) in situ. The invention furthermore relates to a system and a method for predicting the optical outcome of IOL surgery. Use of the system may provide prevention, treatment, or amelioration of diseases and disorders affecting the lens of the eye and which may benefit from IOL surgery. Moreover, the invention relates to a computer-readable medium for implementing such a system on a computer.

Abstract: A device for correcting visual defects of an eye comprises a coherent light source, a beam modification device for shaping and deflecting a beam of the coherent light source, and a wavefront analyzer device for analyzing a wavefront of an optical path in the eye.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.