Abstract: An image acquisition apparatus that uses optical coherence tomography includes a scanning unit provided within a light path that guides signal light to be incident on an examination object towards the examination object and configured to scan the signal light in a main scanning direction; and a control unit configured to control the scanning unit such that an integration time of an optical interference signal per pixel in at least one predetermined area other than opposite ends, in the main scanning direction, of an image acquisition region scanned by a plurality of main scan lines is increased relative to that of an area other than the predetermined area.

Abstract: An optical system and measurement method for imaging three-dimensional objects with low light scatter comprising at least one source of radiation; a radiation projection means for creating a set of foci through a volume of an object; and a means for imaging the returned light from the set of foci on at least one camera, wherein the imaging of the volume of the object is at a different angle from the projection, allowing for detection of the returned light on separate camera pixels. The measurement method further comprises projecting a longitudinal grid of elongated foci through the volume of an object; imaging returned light from the object at a different angle on at least one camera, so as to avoid overlapping the elongated images; and analyzing the imaged, returned light to yield depth information of the object at a multiplicity of points.

Abstract: Methods, systems and software for determining an optical surface model for an optical tissue system using Fourier transformation algorithms. A method of reconstructing optical tissues an eye comprises transmitting an image through the optical tissues of the eye. The surface gradients from the transmitted image are measured across the optical tissues of the eye. A Fourier transform algorithm is applied to the surface gradients to reconstruct an optical surface model that corresponds to the optical tissues of the eye.

Abstract: Process and system for determining the topography of bioelectric response signals of a visual system including a patient's retina, optical nerve or a projection thereof at the level of the central cortex, following visual stimulation through a surface arranged in front of the patient's eye. An image which comprises a plurality of cells is displayed as stimuli, each cell being activated or deactivated according to a corresponding digital time function represented by a cyclical succession of binary m-sequences of duration (T) formed from a plurality of activation symbols (N). Symbols N have a duration (Ts), and the m-sequences of the various cells are obtained cyclically from a mother m-sequence. The process determines the total bioelectric response of the visual system. The response associated with each cell is determined by the total response of the visual system using a cross-correlation with a suitable translated version of a mother m-sequence.

Abstract: An apparatus for generating a two-dimensional image of an object using an optical coherence tomography (OCT) optical system, includes: the OCT optical system including: a light source; a splitter for splitting light emitted from the light source into a measurement optical path and a reference optical path; a scanner arranged in the measurement optical path for scanning the object in at least one of XY directions with the split light; and a detector for detecting a spectrum of combined light of the split light from the measurement optical path reflected on the object and the split light from the reference optical path each XY position of the light on the object, and a processor for generating the two-dimensional image of the object in the XY directions by converting the number of zero cross points of an interference signal contained in the spectrum at each XY position into a luminance value.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

Abstract: Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image.

Abstract: Improved devices, systems, and methods for diagnosing, planning treatments of, and/or treating the refractive structures of an eye of a patient incorporate results of prior refractive corrections into a planned refractive treatment of a particular patient by driving an effective treatment vector function based on data from the prior eye treatments. The exemplary effective treatment vector employs an influence matrix which may allow improved refractive corrections to be generated so as to increase the overall accuracy of laser eye surgery (including LASIK, PRK, and the like), customized intraocular lenses (IOLs), refractive femtosecond treatments, and the like.

Abstract: Systems and methods for using a new corneal ratio, referred to as the Geggel ratio, to estimate how much treatment a patient received at an original myopic or mixed astigmatism excimer laser refractive surgery. The Geggel ratio represents the ratio of the measure of a pre-IOL central pachymetry to a measure of a pre-IOL superior pachymetry. The estimated laser ablation depth (ELAD) is used in a derived linear regression equation to determine an IOL power adjustment that is added to the standard SRK/T formula used to determine IOL power.

Abstract: An imaging system for examining the interior structure of the eye at high-resolution under ambient light without the need for chemical dilation of the pupil.

Abstract: In intraocular observation of the eye, the slit lamp microscope 1causes the illumination light emitted by the illumination system 8 to enter the inside of the eye via the head lens 20 and causes an intraocularly reflected light of this illumination light to enter the observation system 6 via the head lens 20 in a state that an illumination optical axis O2 and an observation axis O1 are arranged so as to be nonparallel and a head lens optical axis OF and the observation optical axis O1 are arranged so as to be separate right and left.

Abstract: A fundus imaging apparatus includes an aberration measurement unit adapted to measure an aberration of reflected light obtained by irradiating an object to be examined with measurement light; an aberration correction unit adapted to correct an aberration of light in accordance with the measured aberration; a control unit adapted to repeatedly control processing of the aberration measurement unit and the aberration correction unit; and a changing unit adapted to change a first function of a predetermined order representing the aberration to a second function including an order higher than the predetermined order in accordance with at least one of a measurement result obtained by the aberration measurement unit and a control result obtained by the control unit. The aberration correction unit corrects an aberration expressed by the second function.

Abstract: An intraocular lens, and a system and method of providing an intraocular lens, having at least one characteristic of the intraocular lens customized in accordance with a modified regression that includes a modification for corneal spherical aberration. The lens, system and method may indicate measuring at least one biometric parameter of an eye at a desired light level, determining a desired postoperative condition of the eye, obtaining a corneal spherical aberration of the eye, applying at least one empirically derived regression calculation, and predictively estimating, in accordance with an output of the at least one empirically derived regression calculation, the at least one characteristic of the intraocular lens to obtain the desired postoperative condition.

Abstract: A method for measuring the dynamic behavior of an optical system is aimed at rendering the dynamic behavior of the optical system objectively detectable. To this end, the optical system to be measured is stimulated by stimuli whereby causing it to react, and the reaction is detected by means of a wave front analysis.

Abstract: The method and the apparatus object of present invention refers to a system and A method that create, save and format text documents using a device with gaze control and a system of quick positioning of the cursor. The present invention provides a faster interaction and requires a minimum effort with respect to the state of the art interfaces.

Abstract: A system for providing enhanced background rejection in thick tissue contains an aberrating element for introducing controllable extraneous spatial aberrations in an excitation beam path; at least one mirror capable of directing received laser pulses to the aberrating element; an objective; a beam scanner imaged onto a back aperture of the objective so that the beam scanner steers beam focus within the thick tissue; and a detector for recording signals produced by the tissue. An associated method comprises the steps of acquiring two-photon excited fluorescence of thick tissue without extraneous aberrations; introducing an extraneous aberration pattern in an excitation beam path; acquiring two-photon excited fluorescence of the thick tissue having the introduced extraneous aberration pattern; and subtracting the two-photon excited fluorescence with extraneous aberrations from the acquired standard two-photon excited fluorescence of the thick tissue without extraneous aberrations.

Abstract: A method and associated system improve accuracy in objective refraction measurements by including the measured distance between the photoreceptors of a subject's eye and the scattering location of light during the objective refraction measurements. Chromatic aberrations in the objective measurements are also compensated. The distance between the photoreceptors and the scattering location may be determined by adjusting a distance between a rotating speckled light pattern and an eye until the speckled light pattern appears to be stationary, or by employing a Scheiner disk.

Abstract: A system and method for automatic visual acuity screening, including: a vision self testing kiosk for performing a visual acuity test. The vision kiosk has a stimulus and multiple mirrors. An image is projected from the stimulus and reflects off of each of the mirrors before exiting the vision kiosk. The mirrors are mounted on a mirror box to define an optical path from the stimulus to a user using the vision kiosk. A microprocessor connected to vision kiosk is able to receive input from the user and report results of vision testing.

Abstract: Device for measuring wave fronts generated by a lens (4) for an eye, with a radiation source (14) for emitting test radiation (12) to be directed at the lens (4) and a sensor device (26) for detecting wave fronts of incident test radiation after interaction with the lens, wherein the sensor device scans the test radiation (20) after interaction with the lens (4) at a scanning frequency which is at least equal in size to the frequency at which changes in wave fronts occur in the test radiation (20) after interaction with the lens (4).

Abstract: The present invention provides methods, systems and software for scaling optical aberration measurements of optical systems. In one embodiment, the present invention provides a method of reconstructing optical tissues of an eye. The method comprises transmitting an image through the optical tissues of the eye. Aberration data from the transmitted image is measured across the optical tissues of the eye at a first plane. A conversion algorithm is applied to the data, converting it to corrective optical power data that can be used as a basis for constructing a treatment for the eye at a second plane.

Abstract: An opthalmological apparatus (1) comprises a base station (11) having a light source (51) for generating light pulses, and an application head (3) which can be mounted on an eye (2) having a light projector (58) for the focussed projection of the light pulses for punctiform breakdown of eye tissue (22). The application head (3) additionally has movement drivers (57) for moving the light projector (58) in a feed direction and in a first scanning direction. A scanner (52) is arranged in the base station (11) in order to deflect the light pulses in a second scanning direction. In addition, the opthalmological apparatus (1) comprises an optical transmission system for transmitting deflected light pulses from the base station (11) to the application head (3), and for superimposing the light pulses deflected in the second scanning direction onto the movement of the light projector (58) in the first scanning direction.

Abstract: Unit for obtaining and displaying fundus image is comprised of a memory that stores a plurality of fundus images wherein a positional relation between an optical axis of an eye ball being examined and an optical axis of an objective is different, an image playback portion for producing a three-dimensional pseudo image by repeatedly displaying a plurality of fundus images on a display in order for a display time set on each fundus image, a CUP contour position designating means for designating a CUP contour position on the three-dimensional pseudo image, means for specifying the CUP contour position designated on the three dimensional pseudo image based upon a specific fundus image, and means for computing CUP contour based upon the specified CUP contour CD position and means for displaying the computed CUP contour.

Abstract: An automated ophthalmic system is disclosed that is utilized to examine the eyes of a subject. A refraction system measures the refractive error of each eye and identifies a lens to correct the refractive error detected. A display presents one or more optotypes to the subject to ascertain the refractive error. An interface device receives a wireless signal from the refraction system, converts the wireless signal into one or more ASCII characters, and communicates the one or more ASCII characters to the display to present the one or more optotypes.

Abstract: A system for providing vision contains an aberrometer, a wavefront sensor, and a transfer optical system. The aberrometer is configured to measure a received wavefront. The aberrometer includes a wavefront sensor and a transfer optical system for transferring an input wavefront so as to the provide the received wavefront at or near the wavefront sensor. The system also includes a processor in communication with the aberrometer, a readable memory, and instructions located within the memory. The readable memory contains one or more system error parameters and instructions for calculating the input wavefront based on the received wavefront and the one or more system error parameters.

Abstract: A surgical microscope assembly includes a microscope main objective and microscope imaging optics. The microscope main objective and microscope imaging optics define a viewing beam path that passes from a sample through the microscope main objective and the microscope imaging optics. The assembly includes an optical coherence tomography (OCT) unit having an illumination beam and a collection beam and a beamsplitter between the microscope main objective and the microscope imaging optics. The beamsplitter is configured to direct a portion of light from the microscope main objective to the microscope imaging optics and to direct another portion of light from the microscope main objective to the OCT unit collection beam. The beamsplitter is further configured to direct an illumination beam from the OCT unit to the microscope main objective and to the sample. A beam forming unit is between the OCT unit and the beamsplitter.

Abstract: An ophthalmic lens with premium vision corrections provides significantly improved visual acuity and contrast sensitivity. The premium vision corrections include precisely correcting for two aberration mode sets simultaneously, second-order astigmatism and fourth-order spherical aberration, instead of correcting for only second-order astigmatism or simultaneously correcting for all aberrations present. Fourth-order astigmatism, sixth-order spherical aberration, and third-order coma are additionally corrected in other premium vision correction schemes. In addition, methods are provided for prescribing and fabricating the premium vision lenses to permit mass customization.

Abstract: A simulator to be used in ophthalmological measurements includes a display apparatus and a control device. The control device is adapted to control the display apparatus in such a manner that the display apparatus displays an image that is adapted to simulate the arrangement of a pupillary midpoint relative to a reference structure.

Abstract: An arrangement for carrying out a surgical treatment of an eye includes a diagnostic instrument which is adapted to register eye-structure data. A data processing unit is adapted to generate, on the basis of the eye-structure data registered by the diagnostic instrument, a structural image that contains at least one mapping of a characteristic eye structure and also at least one positional marking arranged relative to the mapping of the characteristic eye structure. An image-data fade-in device is adapted to fade the structural image generated by the data processing unit into an image generated by a surgical microscope during the implementation of a surgical treatment of the eye.

Abstract: A method and apparatus for modeling a lens of an eye, comprising: measuring the anterior shape of the eye's cornea; determining direct optical measurements of at least one parameter of the cornea and at least one parameter of the lens; determining the refractive index of the cornea; correcting the optical measurements to account for the effect of the refractive index of the cornea on the direct optical measurements; measuring the aberration of the eye; calculating the refractive index of the lens by combining the corrected measurements and the measured aberration; and further correcting the optical measurements of the lens to account the effect of the refractive index of the lens on the direct optical measurements.

Abstract: In general, in some embodiments, the disclosure provides a method that includes making a subjective refraction of a person to determine information about the person's vision, making a wavefront measurement of one or both of the person's eyes to determine information about the optical properties of one or both of the person's eyes (e.g., aberrations), calculating a prescription for the person based on the information about the person's vision and the information about the optical properties of one or both of the person's eyes, and outputting the prescription.

Abstract: The invention relates to an optical measuring system comprising a wave front sensor for characterizing a shape of a wave front of measuring light and an imaging lens, wherein the imaging lens comprises a first optical assembly and a second optical assembly for imaging an object region in an entrance region of the wave front sensor. A distance between the object region and the first optical assembly is larger than a focal length of the first optical assembly. Furthermore, the optical measuring system can comprise an optical microscopy system and optionally an OCT system for carrying out different optical examination methods at the same time.

Abstract: An apparatus is provided for finding and defining a prescription for prism glasses for Diplopic patients and AMD patients whose Macula and Fovea are damaged enough that the patients have double vision, but, still have relatively good acuity. The apparatus positions lenses in infinitely variable locations horizontally and vertically in front of the patient's eyes until the patient indicates that he/she sees the two images fuse. The H-V coordinates of the location of the Optic center of each lens axis in relation to the patient's visual axis are decentration dimensions indicated for each eye by the H and V dials on the apparatus and are thus the basis for an accurate prescription for prism lenses.

Abstract: An opthalmological measurement apparatus (1) is proposed which comprises a first measurement system and a second measurement system. The first measurement system comprises a first light projection system for projection of a first light beam (2) through a cross-sectional part (4) of an eye (3). In addition, the first measurement system comprises image detection means, arranged in the Scheimpflug configuration with respect to the first light beam (2), for detection and storage of a cross-sectional image (30A) of at least one subregion of the cross-sectional part (4) which is illuminated by the first light projection system, from a first position outside the first light beam (2). The second measurement system comprises a second light projection system for projection of a second light beam onto the eye (3), and comprises a wavefront detector (19) for determination and storage of a wavefront profile of the second light beam reflected by the eye (3).

Abstract: The disclosure relates to medical databases, remote monitoring, diagnosis and treatment systems and methods. In one particular embodiment, a system for remote monitoring, diagnosis, or treatment of eye conditions, disorders and diseases is provided. This method generally includes administering a stream of droplets to the eye of a subject from an ejector device, and storing data related to the administration in a memory of the ejector device. The data may then be monitored and analyzed.

Abstract: A binocular indirect opthalmoscope has a light source for producing an illumination beam and an illumination mirror (7) for directing the illumination beam to an eye to be viewed. The opthalmoscope also has, viewing optics including left-hand and right-hand eyepieces (12,13) and an optical splitter (9,10) for directing light along left-hand and right-hand viewing paths to the two eyepieces. An aperture holder (20) is pivotally mounted in a frame (3,5,6) of the opthalmoscope and adjusts the size of the illumination beam, under the control of a manually rotatable control knob (24). The movement of the aperture holder is transmitted, by means of mechanical linkage, to a moveable carriage (15) on which is mounted both the optical splitter and the illumination mirror, so that when the user moves the control knob to adjust the size of the illumination beam the optical splitter and the illumination mirror are also adjusted in position with respect to the opthalmoscope frame.

Abstract: Embodiments of the present invention include approaches for controlling light valve devices to improve the range and precision of the contrast ratio and the grayscale levels of a display used for visual field tests. In one embodiment, two or more illumination devices are used to enable the display device to display a wide range of contrast stimuli at precise illumination intensities over a fixed background illumination level. In another embodiment, the gamma curves of the display elements are adjusted to allow greater variations in the brightness of the display.

Abstract: An adaptive optics ocular fundus observation device that utilizes adaptive optics in observing ocular fundus, which is characterized by further comprising a judging means for judging whether an arrangement of the retinal locations devoid of nerve cells reflects a retinal nerve fiber tract.

Abstract: One embodiment of the present invention accounts for individual anatomical variation when evaluating optical nerve fiber measurements. In one aspect, contextual information is used to compensate or correct measurement data. In another aspect, reference coordinates are remapped for improved comparison or visualization. In one embodiment of this latter aspect, the method uses measurements of nerve fiber capacity and maps of nerve fiber retinal service to improve sensitivity and specificity in eye function metrics. In one instance, we use the birefringence of nerve fibers to determine the orientation of the fibers within the RNFL. Orientation of the fibers about the ONH is indicative of the service provided by the fibers and is used to improve the interpretation of thickness measurements of the nerve fiber layer. Normalized nerve fiber measurements about the optic nerve head improve specificity and sensitivity as compared to the standard model.

Abstract: Axial distances between ocular structures can be measured by focusing an optical unit on focus planes corresponding to the ocular structures and using the distance between focus planes to determine the distance between the ocular structures. The method is particularly useful during eye surgery, e.g., cataract surgery, where the distance between ocular structures, particularly an aphakic pupil, can be used to more accurately predict the effective lens position for an intraocular lens.

Abstract: In an ophthalmologic apparatus in which a head part is moved at a speed according to a rotation speed of a rotational part of a joystick, in order to enable a moving amount of the head part to correspond to a rotation amount even when the rotation speed becomes higher, the rotation speed of the joystick is detected at predetermined intervals, and when a current rotation speed (count of an encoder during a predetermined period) is lower than a previous rotation speed, a speed obtained by subtracting a predetermined value from the previous rotation speed is compared to the current rotation speed. Then, a higher speed is set as the current rotation speed, and the head part is moved at the speed corresponding to the current rotation speed.

Abstract: An apparatus is provided for finding and defining a prescription for reading glasses for an AMD patient whose Macula and Fovea are damaged enough that the patient has double vision, i.e. the patient sees two images of every object within the field of view of the Macula and Fovea. The apparatus positions reading lenses in various locations in front of the patient's eyes until the patient indicates that he/she now sees one image for each object in the field of view of the Macula and Fovea. The X-Y coordinates of the location of each lens axis in relation to the patient's visual axis are offset dimensions indicated for each eye by the apparatus and is thus the prescription for reading lenses.

Abstract: The present invention provides methods, systems and software for scaling optical aberration measurements of optical systems. In one embodiment, the present invention provides a method of reconstructing optical tissues of an eye. The method comprises transmitting an image through the optical tissues of the eye. Aberration data from the transmitted image is measured across the optical tissues of the eye at a first plane. A conversion algorithm is applied to the data, converting it to corrective optical power data that can be used as a basis for constructing a treatment for the eye at a second plane.

Abstract: An ophthalmologic apparatus and a method for the contactless observation, examination, treatment, and/or diagnosis of an eye. The apparatus is structurally based on a fundus camera or an ophthalmoscope. An illumination beam path extends from a first illumination source to the eye and is fitted with a perforated mirror and imaging optics, and an observation beam path extends from the eye to a detector via the imaging optics and through the perforated mirror. The arrangement additionally comprises a beam path for scanning illumination which extends from a second illumination source to the eye and is fitted with a scanning unit, a lens, and a beam splitter in addition to the imaging optics. The scanning unit that is arranged in the beam path for scanning illumination is designed as (an) electrostatically or/and galvanometrically driven bidirectional or unidirectional tilting mirror(s).

Abstract: Selecting an optimal intraocular lens (IOL) from a plurality of IOLs for implanting in a subject eye, including measuring anterior corneal topography (ACT), axial length (AXL), and anterior chamber depth (ACD) of a subject eye; selecting a default equivalent refractive index depending on preoperative patient's stage or calculating a personalized value or introducing a complete topographic representation if posterior corneal data are available; creating a customized model of the subject eye with each of a plurality of identified intraocular lenses (IOL) implanted, performing a ray tracing through that model eye; calculating from the ray tracing a RpMTF or RMTF value; and selecting the IOL corresponding to the highest RpMTF or RMTF value for implanting in the subject eye.

Abstract: An ophthalmologic imaging apparatus that captures a fundus image of a subject's eye includes a first extraction unit configured to extract, from a first fundus image photographed with a first light quantity, an image of a first area having intensity not less than predetermined intensity and an image of a second area other than the first area, a second extraction unit configured to extract an image of an area corresponding to the first area from a second fundus image photographed with a second light quantity based on the light quantity of the first area, a third extraction unit configured to extract an image of an area corresponding to the second area from a third fundus image photographed with a third light quantity based on the light quantity of the second area, and an image combining unit configured to combine the images extracted by the second and the third extraction units.

Abstract: An ophthalmic camera (10) comprising a camera (12) having a lens (18) aligned with a second lens (16) and at least one illumination means (14). The illumination means (14) is capable of movement relative to the camera lens (18) so that the beam of light emitted by the illumination means (14) is able to be focused by the second lens (16) through the pupil onto the fundus. In another embodiment, the ophthalmic camera comprises a camera (52), an illumination means (54) and a beamsplitter (58). The camera (52) and the beamsplitter (58) from an alignment axis X and the illumination means (54) together with the beam splitter (58) form an illumination axis Y perpendicular to the alignment axis X.

Abstract: The invention relates to a method and furthermore a device from the examination of cavities, in particular an eye, by means of laser scanning. The aim of the invention is to carry out further investigations, above all with respect to possible diseases. Said aim is achieved, whereby the determination of the cavity wall thickness, in particular of retinal cavities is carried out. The external diameter and the internal diameter are determined by scanning doppler laser and the wall thickness determined from the data recorded thus.

Abstract: A phase diversity wavefront sensor includes an optical system including at least one optical element for receiving a light beam; a diffractive optical element having a diffractive pattern defining a filter function, the diffractive optical element being arranged to produce, in conjunction with the optical system, images from the light beam associated with at least two diffraction orders; and a detector for detecting the images and outputting image data corresponding to the detected images. In one embodiment, the optical system, diffractive optical element, and detector are arranged to provide telecentric, pupil plane images of the light beam. A processor receives the image data from the detector, and executes a Gerchberg-Saxton phase retrieval algorithm to measure the wavefront of the light beam.

Abstract: The invention relates to a method for determining the location of the ocular pivot point (ADL) in an eye (10) of a test person. In the method, the mean curvature (KH) of the cornea (14) of the eye (10) is determined. The mean phase error (PF) of the eye (10) is determined as is the eye length (LA) from the mean curvature (KH) and the mean phase error (PF). The location of the ocular pivot point (ADL) is determined from the eye length (LA).

Abstract: Various embodiments of methods and systems for improving and enhancing vision are disclosed. Adjustable lenses or optical systems may be used to provide adaptive vision modification. In some embodiments, vision modification may be responsive to the current state of the user's visual system. Certain embodiments provide correction of the subject's near and far vision. Other embodiments provide enhancement of vision beyond the physiological ranges of focal length or magnification.