Abstract: A measurement device for generating an arterial volume-indicative signal includes an exciter and a detector. The exciter is adapted to receive an oscillating signal and generate a pressure wave based at least in part on the oscillating signal on the artery at a measurement site on a patient. The pressure wave includes a frequency. The detector is placed sufficiently near the measurement site to detect a volumetric signal indicative of arterial volume of the patient.
Type:
Grant
Filed:
November 12, 2009
Date of Patent:
May 31, 2011
Assignee:
Masimo Corporation
Inventors:
Bryan Patrick Flaherty, Mark Henry Sher, Richard G. Caro
Abstract: The invention relates to a method for determining a probability distribution with local three-dimensional resolution for a substance in a vascular system. An acquisition time is assigned to a group of x-ray images showing a presence distribution with local 2D resolution for a substance in the vascular system at the acquisition time. A first preliminary presence probability distribution is determined using the x-ray images assigned to the acquisition time and a volume data set of the vascular system. A second preliminary presence probability distribution is determined using the presence probability distribution for the preceding acquisition time and a migration probability distribution with the substance migrating from first vascular locations to second vascular locations. A high individual probability to vascular locations is assigned if both preliminary presence probability distributions have a high probability value for the respective vascular location.
Abstract: The invention relates to indicator dilution measurements of a central volume (V1) with a first site of injection (S1) upstream of the central volume (V1) a second site of detection (S2) of the diluted indicator downstream of the central volume (V1), wherein a first additional volume (V2) is defined between the first site (S1) and the central volume (V1) and a first additional branch (B2) is defined between the first site (S1) and the central volume (V1) and wherein a second additional volume (V3) is defined between the central volume (V1) and the second site (S2) and a second additional branch (B3) is defined between the central volume (V1) and the second site (S2) wherein a result of central volumetric parameters are corrected for the first and second additional volumes (V2, V3) and/or for the first and second additional branches (B2, B3).
Type:
Application
Filed:
October 15, 2008
Publication date:
May 5, 2011
Inventors:
Ulf Borg, Reinhold Knoll, Frederic Michard, Ulrich Pfeiffer
Abstract: Systems and methods provide for assessing a patient's hemodynamic response to a drug therapy. A patient's hemodynamic response to a drug therapy is monitored using sensor data acquired using one or more sensors. The patient's hemodynamic response to the drug therapy is quantified, such as by quantifying a patient's sensitivity or refractoriness to the drug therapy. The quantified data may be used to optimize a patient's drug therapy, among other uses.
Type:
Grant
Filed:
May 10, 2006
Date of Patent:
April 19, 2011
Assignee:
Cardiac Pacemakers, Inc.
Inventors:
Yousufali H. Dalal, Marina Brockway, Richard O. Kuenzler
Abstract: A system and method for detecting, monitoring and analyzing physiological characteristics. Signals from a subject are acquired from a suite of sensors, such as temperature, carbon dioxide, humidity, light, movement, electromagnetic and vibration sensors, in a passive, non-invasive manner. The signals are processed and physiological characteristics are isolated for analysis. The system and method are to analyze sleep patterns, as well as to prevent bed sores or detect conditions such as illness, restless leg syndrome, periodic leg movement, sleep walking, or sleep apnea. However, numerous other applications of the invention are also disclosed.
Type:
Application
Filed:
August 30, 2010
Publication date:
April 14, 2011
Applicant:
WellAWARE Systems, Inc.
Inventors:
David C. Mack, Steve Kell, Majd Alwan, Robin Felder, Beverly Turner, Sarah Wood
Abstract: Embodiments of the present invention relate to a method for analyzing pulse data. In one embodiment, the method comprises receiving a signal containing data representing a plurality of pulses, the signal generated in response to detecting light scattered from blood perfused tissue. Further, one embodiment includes performing a pulse identification or qualification algorithm on at least a portion of the data, the pulse identification or qualification algorithm comprising at least one constant, and modifying the at least one constant based on results obtained from performing the pulse identification or qualification algorithm, wherein the results indicate that a designated number of rejected pulses has been reached.
Abstract: The present invention specifies a method and system for assessing the dynamic respiratory arterial pressure wave using plethysmographic sensing techniques. The dynamic respiratory arterial pressure wave is measured and plotted for purposes of diagnosis and or remedial biofeedback.
Abstract: A system for gaining access to an interventional site within vasculature through a vessel wall or other structure such as that of a medical device. An apparatus is provided to accomplish a sealed worksite as are sensor delivery systems including sealable sensor devices that are adapted to be placed at the interventional site.
Type:
Grant
Filed:
October 8, 2004
Date of Patent:
April 5, 2011
Assignee:
Endovascular Technologies, Inc.
Inventors:
Peter S. Brown, Albert K. Chin, Arnold M. Escano, Gregory W. Fung, Rasean L. Hamilton, Juan I. Perez, Richard Rapoza, Shuji Uemura, Michael F. Wei, Arlene S. Yang
Abstract: Methods and apparatus for determining a cardiac parameter from cardiovascular pressure signals including arterial blood pressure (ABP) and the photoplethysmographic signal to quantify the degree of amplitude modulation due to respiration and predict fluid responsiveness are disclosed. Disclosed embodiments include a method for assessing fluid responsiveness implemented in a digital computer with one or more processors comprising: (a) measuring a cardiovascular signal, and (b) computing a dynamic index predictive of fluid responsiveness from said cardiovascular signal using a nonlinear state space estimator. According to one particular embodiment, and without limitation, the nonlinear state space estimator is based on a model for cardiovascular signals such as arterial blood pressure or plethysmogram signals, and employs a marginalized particle filter to estimate a dynamic index predictive of fluid responsiveness that is substantially equivalent to a variation in pulse pressure of said cardiovascular signal.
Abstract: Disclosed herein is a catheter for a left coronary artery having a distal end for being introduced into an opening of the left coronary artery from an artery of an arm. The catheter can include a catheter main body including a main body portion of a substantially linear shape in a natural state thereof and a curved portion extending from the main body portion to form a portion that extends to the distal end and has a curved shape in a natural state thereof.
Type:
Application
Filed:
September 28, 2010
Publication date:
March 31, 2011
Inventors:
Ayumu Takagi, Hiroyoshi Ise, Daisuke Nakashima, Tetsuya Fukuoka
Abstract: An implanted heart monitor includes sensors that measure various aspects of the heart failure patient's heart. A remote heart monitoring system connects the implanted heart monitor to a care provider, such as a physician. The data provided by the implanted heart monitor permits the care provider to obtain valuable data on the heart in order to make health care decisions affecting the heart failure patient's treatment. In many cases, the measurement of core body temperature and other patient data will enable the care provider to alter the patient's treatment to address the patient's condition. The implanted heart monitor can communicate over a wireless communication link with an external monitor. The implanted heart monitor may be implemented as part of a pacing device (i.e., pace maker) or may be a separate unit devoted to monitoring functions. The external monitor communicates with a monitoring station over a communication link.
Abstract: Methods, systems and devices are provided for reducing the amount of data, processing and/or power required to analyze hemodynamic signals such as photoplethysmography (PPG) signals, pressure signals, and impedance signals. In response to detecting a specific event associated with a cyclical body function, a hemodynamic signal is continuously sampled during a window following the detecting of the specific event, wherein the window is shorter than a cycle associated with the cyclical body function. The hemodynamic signal is then analyzed based on the plurality of samples.
Abstract: Method and system for using segmentation and three-dimensional image-processing techniques of a method to create an automatic method to detect coronary artery calcification deposits and identify their location with respect to a major coronary artery. Finally, different scoring algorithms can be applied to generate calcium scores such as Agatston Janovitz, Mass, and Volume. A total score and a more detailed score can be generated based on the major arteries such as right coronary artery, left anterior descending artery, or left circumflex artery to be incorporated into the patient report.
Type:
Grant
Filed:
January 2, 2007
Date of Patent:
March 15, 2011
Assignee:
General Electric Company
Inventors:
Peter Lehel, Saad A Sirohey, DeAnn M Haas, Pradipto Kolay
Abstract: A method of determining an impedance of at least one lung of a patient having an implanted pacemaker that comprises first and second leads and a case, the method comprising: a) using the leads and the case to acquire at least a first and a second impedance measurement responsive to impedance of the patient's chest that are at least partially independent; and b) using the impedance measurements to determine the impedance of at least one of the lungs substantially independently of impedance of the other lung.
Type:
Grant
Filed:
September 13, 2005
Date of Patent:
March 15, 2011
Assignee:
Tel Aviv University Future Technology Development L.P.
Abstract: Embodiments of the present invention are directed to a physiological monitoring device which is configured to record signals that reflect blood flow and/or blood pressure, and which may also record ECG signals. In one embodiment, a portable monitoring device comprises a plurality of impedance electrodes configured to be coupled to a patient's body and to generate an AC current with an electrical field to detect local electrical impedance of a portion of the patient's body encompassed by the electrical field, the local electrical impedance being a surrogate measure of local blood flow of the portion of the patient's body. At least a portion of the portable monitoring device is configured to be insertable subcutaneously into the patient's body.
Type:
Grant
Filed:
May 10, 2005
Date of Patent:
March 1, 2011
Assignee:
Regents of the University of Minnesota
Inventors:
David G. Benditt, Robert F. Patterson, Keith G. Lurie
Abstract: A portable device having a biosignal measuring instrument includes: at least one first electrocardiogram signal sensor portion on a first surface of the portable device that contacts a first hand of a user, to measure a first electrocardiogram signal of the user; at least one second electrocardiogram signal sensor portion on a second surface of the portable device that contacts a wrist of a second hand of the user, to measure a second electrocardiogram signal from the wrist; a pulse waveform sensor on the second surface and in parallel with the second electrocardiogram signal sensor portion, to sense a pulse waveform from the wrist; a waveform controller generating an electrocardiogram waveform of the user from the measured first electrocardiogram signal and second electrocardiogram signal, generating a pulse waveform of the user from the sensed pulse waveform, and detecting at least one characteristic point of the pulse waveform by referring to the electrocardiogram waveform; and an output portion providing
Type:
Grant
Filed:
May 12, 2006
Date of Patent:
March 1, 2011
Assignee:
Samsung Electronics Co., Ltd.
Inventors:
Wan Taek Han, Jin Sang Hwang, Sang Hoon Shin, Hyung Sok Yeo
Abstract: A device for monitoring cardiac pacing rate having a measuring unit for receiving an electrical signal representing the patient's cardiac demand, and a computing unit for determining the myocardial energy balance by calculating energy consumed by the myocardium for both an external dynamic work for pumping blood into a vascular system, and an internal static work of the myocardium. Volume and time based measurements are used, and in one embodiment, volumes are estimated and volume ratios are calculated from volume estimates. In another embodiment, volumes are estimated from bioimpedance measurements. A further aspect is a rate adaptive pacemaker, wherein the maximum pacing rate is determined from the myocardial energy balance such that the energy supplied to the myocardium approximately equals the energy consumed by the myocardium for both an external dynamic work for pumping blood into a vascular system and an internal static work of the myocardium.
Type:
Grant
Filed:
August 30, 2007
Date of Patent:
February 22, 2011
Assignee:
Smartimplant OÜ
Inventors:
Andres Kink, Mart Minn, Toomas Parve, Indrek Rätsep
Abstract: This document describes a fitness test application which allows the user to exercise freely (running and cycling outdoors, bicycle ergometer, rowing ergometer, treadmill) and which provides an estimate of user's fitness during and/or after the exercise. The analysis can be performed either as real-time or as post-analysis.
Type:
Application
Filed:
May 4, 2009
Publication date:
February 17, 2011
Applicant:
FIRSTBEAT TECHNOLOGIES OY
Inventors:
Mikko Seppanen, Aki Pulkkinen, Veli-Pekka Kurunmaki, Sami Saalasti, Joni Kettunen
Abstract: The invention relates to a method and a device for removing respiratory artefacts in invasive blood pressure measurements. The level of CO2 in the expired air is monitored during blood pressure measurement and used to approximate and remove the respiratory artifacts. In one embodiment, the respiratory frequency from the respiratory signal is extracted by identifying the end-tidal CO2 level for each breath. A model is derived for the respiratory artifacts using the respiratory frequency, and the model is subtracted from the measured blood pressure data.
Type:
Grant
Filed:
September 28, 2006
Date of Patent:
February 15, 2011
Assignee:
Siemens Aktiengesellscahft
Inventors:
Kenneth Danehorn, Fredrik Gustafsson, Martin Wikström
Abstract: A device for detecting the state of a heart on the basis of intracardial impedance measurement. The device has an impedance measuring unit, which has electrical terminals, configured to be electrically connected or to be connected to electrodes for delivering and detecting a current or voltage, and is implemented to ascertain an impedance on the basis of the dimension of the delivered current or voltage and the voltage drop caused by the current or the current caused by the voltage, as well as an analysis unit, which is connected to the impedance measuring unit and is implemented to derive a cardiac function parameter from a time curve of the impedance ascertained using the impedance measuring unit. The analysis unit analyzes the impedance curve assigned to a diastole and derives a cardiac function parameter characterizing the behavior of a heart during the diastole (filling phase of the ventricle).
Type:
Grant
Filed:
September 7, 2006
Date of Patent:
February 8, 2011
Assignee:
Biotronik CRM Patent AG
Inventors:
Michael Lippert, Gerald Czygan, Stefan Paule
Abstract: Elasticity of a cardiovascular vessel of a patient is monitored to provide an indication of whether the patient's health is changing. In some aspects the elasticity of a cardiovascular vessel is determined irrespective of the current blood pressure level of the patient at the time the elasticity is determined. For example, vessel elasticity may be determined based on a defined set of data that maps vessel elasticity with reflectance times for different blood pressure levels. In some implementations, this set of data corresponds to a set of iso-pressure lines.
Abstract: This document discusses, among other things, a cardiac rhythm management device or other implantable medical device that uses thoracic impedance to determine how much fluid is present in the thorax, such as for detecting or predicting congestive heart failure, pulmonary edema, pleural effusion, hypotension, or the like. The thoracic fluid amount determined from the thoracic impedance is compensated for changes in blood resistivity, which may result from changes in hematocrit level or other factors. The blood-resistivity-compensated thoracic fluid amount can be stored in the device or transmitted to an external device for storage or display. The blood-resistivity-compensated thoracic fluid amount can also be used to adjust a cardiac pacing, cardiac resynchronization, or other cardiac rhythm management or other therapy to the patient. This document also discusses applications of the devices and methods for predicting or indicating anemia.
Type:
Grant
Filed:
December 1, 2009
Date of Patent:
February 1, 2011
Assignee:
Cardiac Pacemakers, Inc.
Inventors:
Jeffrey E. Stahmann, John D. Hatlestad, Boyce Moon
Abstract: The present invention provides methods for increasing arterial compliance. The methods generally involve administering to an individual in need thereof an effective amount of relaxin. The present invention further provides methods of increasing arterial compliance in individuals who have Type 1 or Type 2 diabetes. The present invention further provides methods of increasing arterial compliance in perimenopausal, menopausal, and post-menopausal women. The present invention further provides methods of increasing arterial compliance in individuals who have or who are at risk of developing age-associated arterial stiffness.
Type:
Grant
Filed:
March 18, 2005
Date of Patent:
February 1, 2011
Assignee:
University of Pittsburgh- Of The Commonwealth System of Higher Education
Abstract: A method for monitoring a patient employs hypothesis testing against each of several monitored signals to determine whether an artifact is present in the monitored signals. In the hypothesis testing, a null hypothesis includes an assumption that pairs of samples of highly correlated monitored signals of the several monitored signals have a predetermined distribution. The method determines that an artifact may exist in one of the monitored signals when the likelihood that the null hypothesis is true falls below a predetermined confidence value. This method can be embodied in an intelligent module for processing multiple data from one or more patients to filter out clinically significant changes in the patient from those changes caused by artifacts.
Abstract: A medical device and method for determining baroreflex sensitivity (BRS) based on one or more respiration cycles. The BRS determination may be performed continuously based on measurements of heart rate, blood pressure, and respiration cycles.
Abstract: An internal tissue including a lesion region in the human body is modeled as a three-dimensional model. By reconstructing thickness or flexibility of a lumen wall portion including the lesion region and making it possible to confirm a motion of the lumen wall or a flow of fluid in the inside of the lumen wall, a state of the lesion region in the lumen can be confirmed clearly by visual inspection or the like. As a result, the diagnosis in the lumen can be made easier.
Abstract: A scientific method and system for determining a customized essential oil blend through accessing a physiolocial data from a user are disclosed in the present invention. The physiological data is heart rate vairiability (HRV), which is associated with cardiac diseases and the autonomic nervous system.
Abstract: Systems and methods obtain information that allows detection of whether a patient suffers from congestion by monitoring a response of the patient to a recumbent position of the patient's body. The patient may be monitored to determine a respiration pattern for a non-recumbent position such as standing and a respiration pattern for a recumbent position such as lying down. The two patterns may be compared, either by a processing device or a physician, to determine a difference in the two respiration patterns. Furthermore, the congestion may be inferred from detecting an amount of time that the patient spends in a recumbent position or from detecting the recumbent angle that the patient obtains, either of which is presumed to indicate whether a recumbent position presents discomfort to the patient due to the presence of congestion.
Type:
Application
Filed:
September 22, 2010
Publication date:
January 13, 2011
Inventors:
John Hatlestsad, Qingsheng Zhu, Jeffrey E. Stahmann
Abstract: 2-D projection images show the temporal profile of the distribution of a contrast medium in an examination object, which contains a vascular system and its surroundings. Each projection image comprises pixels with pixel values. The pixel values of pixels corresponding to one another in the projection images are defined by at least essentially locationally identical areas of the examination object. A computer assigns a uniform 2-D evaluation core that is uniform for all corresponding pixels at least in a sub-area of pixels corresponding to one another in the projection images that is uniform for the projection images. The computer defines at least one characteristic value for each pixel within each projection image based on the evaluation core assigned to the pixel and assigns it to the relevant pixel.
Abstract: Methods for monitoring cardiovascular conditions, i.e., hyperdynamic circulation, vasodilation, vasoconstriction, or central-to-peripheral arterial pressure decoupling conditions are described. These methods involve measuring a central signal proportional to or a function of the subject's heart activity and a peripheral signal proportional to or a function of a signal related to the central signal. Then calculating a time difference between features in the central and peripheral signals representing the same heart event. The cardiovascular condition is indicated if the time difference is greater or lower than a threshold value, if the time difference is greater or lower than a threshold value over a specified period of time, or if there is a significant statistical change in the times over the specified time period. These methods can alert a user that a subject is experiencing the cardiovascular condition, which can enable a clinician to appropriately provide treatment to the subject.
Abstract: Lumen-traveling devices and associated methods and systems are described. Lumen-traveling devices capable of traveling within a body lumen may include a propelling mechanism to produce movement of the lumen-traveling device within the lumen, as well as additional components such as a sensor, an active portion, and/or control circuitry. In some embodiments, a sensor may be used to detect a local condition, and an action may be performed within the body lumen. Actions that may be performed include, but are not limited to, transmitting information, releasing a material within the lumen, performing a surgical step, or collecting a sample, among others.
Type:
Grant
Filed:
December 21, 2006
Date of Patent:
December 28, 2010
Assignee:
Invention Science Fund I, LLC
Inventors:
Bran Ferren, W. Daniel Hillis, Roderick A. Hyde, Muriel Y. Ishikawa, Edward K. Y. Jung, Eric C. Leuthardt, Nathan P. Myhrvold, Elizabeth A. Sweeney, Clarence T. Tegreene, Lowell L. Wood, Jr., Victoria Y. H. Wood
Abstract: A sequence of groups of projection images shows an object under examination comprising a vascular system and its environment. A computer determines a 2-dimensional evaluation image having a plurality of pixels based on combination images determined from the projection images of a group. The combination images have a plurality of pixels with pixel values. The sequence of the combination images shows the time characteristic of the distribution of a contrast medium in the object. The pixels of the evaluation image correspond to those of the projection images. The computer assigns each pixel, at least in a part area of the evaluation image, a type that is characteristic of whether the respective pixel corresponds to a vessel of the vascular system, a perfusion area or a background. It performs the assignment of the type on the basis of the time characteristic of the pixel values of the combination images.
Type:
Grant
Filed:
May 31, 2007
Date of Patent:
December 28, 2010
Assignee:
Siemens Aktiengesellschaft
Inventors:
Philipp Bernhardt, Estelle Camus, Martin Hoheisel, Thomas Redel
Abstract: The present invention relates to a system and method for performing a protocol-driven ultrasound examination for generating an image of moving cardiac structure and blood of a heart. One embodiment comprises a front-end and at least one processor. The front end is arranged to transmit ultrasound waves into the moving cardiac structure and blood, generating received signals in response to the ultrasound waves backscattered from the moving cardiac structure and blood. The at least one processor, responsive to the received signals, acquires at least one image of the structure in at least one of a predetermined order and a predefined protocol, and selects at least one of the acquired images taken along at least one of a given view and study.
Type:
Grant
Filed:
April 5, 2007
Date of Patent:
December 28, 2010
Assignee:
General Electric Company
Inventors:
Peter Lysyansky, Israel Raz, Zvi Friedman
Abstract: A method for monitoring an individual's physiological condition and detecting abnormalities therein, comprising concurrently receiving an electrocardiograph signal and a ballistocardiograph signal. The electrocardiograph and ballistocardiograph signals are conditioned to minimize background extraneous noise after which, each signal is concurrently processed and analyzed to detect repeating cyclical patterns and further characterized to identify individual components of the repeating cycles. At least one individual component in one signal is selected as a reference marker for a selected component in the other signal. The two signals are then synchronized, outputs produced therefrom and stored in a database.
Abstract: The invention relates to medicine. The inventive method for non-evasively determining an endothelial function consists in reducing a transmural pressure in a limb, recording the amplitude of plethysmographic signals at different pressures, determining the pressure of a maximum plethysmographic signal amplitude, reducing the pressure to a value corresponding to the specified percentage of the maximum amplitude, carrying out an occlusion sample in the course of which a pressure higher by at least 50 mm Hg than the systolic pressure of a tested patient is produced in a cuff arranged proximally to the located limb area, wherein the occlusion is carried out during at least 5 minutes.
Type:
Application
Filed:
April 3, 2006
Publication date:
November 25, 2010
Inventors:
Alexander Sergeevich Parfyonov, Maria Alexandrovna Parfyonova
Abstract: Systems and methods obtain information that allows detection of whether a patient suffers from congestion by monitoring a response of the patient to a recumbent position of the patient's body. The patient may be monitored to determine a respiration pattern for a non-recumbent position such as standing and a respiration pattern for a recumbent position such as lying down. The two patterns may be compared, either by a processing device or a physician, to determine a difference in the two respiration patterns. Furthermore, the congestion may be inferred from detecting an amount of time that the patient spends in a recumbent position or from detecting the recumbent angle that the patient obtains, either of which is presumed to indicate whether a recumbent position presents discomfort to the patient due to the presence of congestion.
Type:
Grant
Filed:
September 4, 2008
Date of Patent:
October 26, 2010
Assignee:
Cardiac Pacemakers, Inc.
Inventors:
John D. Hatlestad, Qingsheng Zhu, Jeffrey E. Stahmann
Abstract: A method, apparatus and software program for measuring a parameter relating to the heart-lung system of a mammal are described. The method, software and apparatus can be implemented in a dialysis or other blood treatment apparatus comprising an extracorporeal blood circuit connected to a mammal; the circuit comprises a dialyzer, or other treatment unit, having a blood inlet, a blood outlet, a treatment fluid inlet and a treatment fluid outlet. The method comprises the steps of providing a pulse of a detectable substance in the blood circuit, measuring an integrated concentration of the detectable substance on the dialysis fluid outlet, determining the parameter based on the measurements on the dialysis fluid outlet.
Abstract: A physiology sensing apparatus with navigation capability is disclosed, which integrates therein a GPS module, a magnetic sensor, an inertial sensing module, and a bio sensing module so as to acquire signals relating to a user's coordinate position, physical condition, body movement, and so on, and then the acquired signals can be purified by filter devices so as to reduce the interference of noise, thereafter, processes the filtered signal by a signal processor and an alarming device so as to simultaneously obtain the information of user's location, physical condition, and whether the user is in danger or having an accident.
Type:
Application
Filed:
July 17, 2006
Publication date:
October 14, 2010
Inventors:
Ming-Jye Tsai, Yung-Yu Chen, Shi-Hao Wang
Abstract: Method and apparatus for monitoring the sleep state condition of an individual by using an external probe applied to a peripheral body location, such as the individual's finger or toe, for detecting changes in the peripheral vascular bed volume of the individual. A predetermined pressure field is applied to the distal end of the peripheral body location, including its distal-most extremity, to prevent the occurrence of venous pooling within and distal to the peripheral body location. The probe produces an output corresponding to changes in the peripheral arterial bed volume at the peripheral body location, which output provides an indication of the sleep state condition of the individual. Such information is useful in diagnosing and/or in treating, a number of sleep disorders as well as other conditions, such as impotence, diabetes, and various disorders in children.
Type:
Grant
Filed:
July 16, 2002
Date of Patent:
October 5, 2010
Assignee:
Itamar Medical Ltd.
Inventors:
Peretz Lavie, Robert P. Schnall, Jacob Sheffy, Giora Pillar
Abstract: A method for diagnosis includes receiving a signal associated with blood oxygen saturation of a patient during sleep. The signal is filtered so as to eliminate signal components at frequencies equal to and greater than a respiratory frequency of the patient. The filtered signal is processed to detect a pattern corresponding to multiple cycles of periodic breathing.
Abstract: A monitoring system is provided that enables the monitoring of a heart in a living organism by continuously measuring both pressure and volume in a chamber of the heart, preferably the left ventricle (LV). The pressure and volume measurements are acquired using a single sensing tip and are communicated to a transmitting device to be wirelessly transmitted to a receiving device, wherein they are used to monitor the heart. The system may also incorporate a temperature measurement that can be transmitted with the volume and pressure measurement to provide further data for monitoring. The system may also extract an electrocardiogram (ECG) signal from the volume measurement. This allows the monitoring of up to four signals that can be used to determine the beat by beat state of cardiac output and any changes caused by disease or therapy.
Type:
Grant
Filed:
August 22, 2005
Date of Patent:
September 28, 2010
Assignee:
Scisense Inc.
Inventors:
Peter Plouf, Blair Poetschke, Milan Placko, Kim Wood, Mohammad Maymandi-Nejad
Abstract: A method for diagnosis includes receiving a signal associated with respiration of a patient during sleep, and processing the signal to detect occurrences of a pattern corresponding to multiple cycles of periodic breathing. A cumulative duration of the occurrences is computed, and a prognosis of the patient is determined based on the cumulative duration.
Abstract: The present invention relates to a method for simultaneously determining the position and velocity of objects. Moreover the method comprising the steps of: 1) simultaneously generating a first signal for determining the velocity and a second signal for determining the position; 2) mixing the first signal with the second signal to form a mixed signal and subsequently transmitting the mixed signal towards an object using a transmitter, so that the mixed signal can be at least partially reflected by the object; and 4) evaluating an echo signal. Such a method may be used for various applications, such as monitoring blood vessel access and/or for pericardiocentesis, as well as for determining the blood flow velocity and the position of blood vessels.
Abstract: A system and method of modeling a circulatory system including a regulatory mechanism parameter. In one embodiment, a regulatory mechanism parameter in a lumped parameter model is represented as a logistic function. In another embodiment, the circulatory system model includes a compliant vessel, the model having a parameter representing a change in pressure due to contraction of smooth muscles of a wall of the vessel.
Type:
Grant
Filed:
March 23, 2006
Date of Patent:
September 14, 2010
Assignee:
University of Vermont and State Agricultural College
Abstract: Minimizing the temporal width of the gating window during calculation of the gating function in cardiac CT may not result in best image quality with a maximum of signal-to-noise ratio and minimal artifacts. According to an exemplary embodiment of the present invention, the widths of the gating windows in cardiac CT are selected on the basis of a motion model describing the motion of the heart. According to an aspect of the present invention, the widths of the gating windows are determined by considering the duration of stationary cardiac phases. Thus, artifacts, such as motion artifacts or noise, are minimized.
Type:
Grant
Filed:
June 14, 2005
Date of Patent:
September 7, 2010
Assignee:
Koninklijke Philips Electronics N.V.
Inventors:
Robert Manzke, Michael Grass, Thomas Koehler
Abstract: A system and method for detecting, monitoring and analyzing physiological characteristics. Signals from a subject are acquired from a suite of sensors, such as temperature, carbon dioxide, humidity, light, movement, electromagnetic and vibration sensors, in a passive, non-invasive manner. The signals are processed and physiological characteristics are isolated for analysis. The system and method are to analyze sleep patterns, as well as to prevent bed sores or detect conditions such as illness, restless leg syndrome, periodic leg movement, sleep walking, or sleep apnea. However, numerous other applications of the invention are also disclosed.
Type:
Grant
Filed:
July 7, 2008
Date of Patent:
August 31, 2010
Assignee:
Home Guardian LLC
Inventors:
David C. Mack, Steven W. Kell, Majd Alwan, Robin Felder, Beverly Turner, Sarah Wood
Abstract: An embodiment of an apparatus for locating a surface of a body lumen is disclosed. The apparatus includes a locator assembly that has a distal end region configured to extend into an opening of the body lumen and to selectably engage at least a portion of the body lumen adjacent to the opening. The distal end region includes at least one surface engaging element that is configured to engage the surface of the body lumen. The apparatus includes a measuring device that is in electrical communication with the surface engaging element. The measuring device is configured to determine changes in measurable characteristics of the surface engaging element. Methods and apparatus for locating a surface of a body lumen are also disclosed.
Abstract: In a method, system and device for treating aneurysm a member is placed around the aneurysm, the aneurysm can be treated and monitored. The member can comprise a sensor placed in relation to a wall portion of the aneurysm for generating a signal corresponding to a parameter related to the aneurysm or the treatment of the aneurism. For example the size of the aneurysm such as the diameter of the aneurysm can be monitored. Hereby changes in the aneurism can be detected and information about the changes of the aneurysm can be used when determining how to treat the aneurysm.
Abstract: Systems and methods involve use of a medical device comprising sensing circuitry. One or more respiratory parameters are detected using the device. Patient baseline weight is provided, and an output signal indicative of a patient's congestive heart failure status is generated based on a change in the one or more respiratory parameters and a change in the patient's measured weight or predicted weight relative to the patient baseline weight. The respiratory parameters may include one or more of respiration rate, relative tidal volume, an index indicative of rapid shallow breathing by the patient, an index derived by computing a respiration rate and a tidal volume for each patient breath, and an index indicative of dyspnea, for example.
Type:
Grant
Filed:
September 16, 2005
Date of Patent:
August 17, 2010
Assignee:
Cardiac Pacemakers, Inc.
Inventors:
Yi Zhang, John D. Hatlestad, Yousufali H. Dalal, Marina Brockway
Abstract: An exemplary method includes providing left atrial pressure information, based at least in part on the information, determining a weight and, based at least in part on the weight, determining a threshold for use in intrathoracic impedance monitoring. Such an exemplary method may include comparing an intrathoracic impedance to the threshold, comparing an intrathoracic impedance change to the threshold, or comparing a product of intrathoracic impedance and time to the threshold. Various exemplary methods, devices, systems, etc., are disclosed.