Abstract: A peak-relevant value device acquires a peak-relevant value (for example, the peak value of an R wave (R peak value)) every cycle from an electrocardiogram acquired. The frequencies of the peak-relevant value acquired as time-series data and the magnitudes for the respective frequencies are analyzed. A peak-relevant value LF calculating device calculates an LF component (peak-relevant value LF component) from the frequency component of the peak-relevant value. An interval acquiring device acquires the interval between characteristic points of the electrocardiographic complex from the electrocardiogram acquired and the frequencies of the feature point interval acquired as time-series data to acquire the magnitudes of the respective frequency component are analyzed.

Abstract: A device for detecting a cardiac event is disclosed. Detection of an event is based on a test applied to a parameter whose value varies according to heart rate. Both the parameter value and heart rate (RR interval) are filtered with an exponential average filter. From these filtered values, the average change in the parameter and the RR interval are also computed with an exponential average filter. Before computing the average change in the parameter, large changes in the parameter over short times, which may be caused by body position shifts, are attenuated are removed, so that the average change represents an average of small/smooth changes in the parameter's value that are characteristic of acute ischemia, one of the cardiac events that may be detected. The test to detect the cardiac event depends on the heart rate, the difference between the parameter's value and its upper and lower normal values, and its average change over time, adjusted for heart rate changes.

Abstract: A biometric monitoring device measuring various biometric information is provided that allows the person to take and/or display a heart rate reading by a simple user interaction with the device, e.g., by simply touching a heart rate sensor surface area or moving the device in a defined motion pattern. Some embodiments of this disclosure provide biometric monitoring devices that allow a person to get a quick heart rate reading without removing the device or interrupting their other activities. Some embodiments provide heart rate monitoring with other desirable features such as feedback on data acquisition status.

Abstract: A defibrillator including the function for measuring motion artifact generated when pressing the heart, and method of operating the defibrillator are provided. The defibrillator includes: a first pair of electrodes including a first main electrode and a first sub-electrode arranged adjacent to and insulated from the first main electrode; a second pair of electrodes including a second main electrode and a second sub electrode arranged adjacent to and insulated from the second main electrode; a first measuring unit measuring a first action potential associated with the first pair of electrodes by using the potential difference between the first pair of electrodes; a second measuring unit measuring a second action potential associated with the second pair of electrodes by using the potential difference between the second pair of electrodes; and an estimating unit estimating ECG artifacts associated with the difference between the first action potential and the second action potential.

Abstract: Various examples are provided for automation of QRS detection. In one example, among others, a system includes an integrate and fire (IF) sampler that can generate an IF pulse train from an analog input signal, and decision logic circuitry that can determine whether a QRS complex waveform is present in a pulse segment of the IF pulse train. In another example, a method includes generating an integrate and fire (IF) pulse train from an analog input signal, identifying a pulse segment of the IF pulse train, and determining whether a QRS waveform is present in the pulse segment based at least in part upon attributes associated with the pulse segment.

Abstract: Methods and systems for assessing cardiac fibrillogenicity in a patient includes generating a map of a duration of one or more measurements indicative of a number of electrical circuit cores and distribution of the electrical circuit cores across a cardiac tissue substrate in the patient's heart in response to electrical activity in the cardiac tissue substrate, the map being registered onto a representation of the patient's heart, applying a set of executable instructions to the map to define an optimal placement of at least one ablation lesion in the cardiac tissue substrate, and calculating total length of the at least one ablation lesion, wherein the total length measure is indicative of the patient's cardiac fibrillogenicity to inform treatment using catheter ablation.

Abstract: A system for remote communication of physiological information from one person to another and, more particularly, the mutual communication of heartbeat between two persons. The system comprises a web server which cooperates with two remote installations identified as A and B. Each of the remote installations comprises a heartbeat sensor, a pillow, and a local host. The local host may be a personal computer or laptop, or a suitable mobile phone running an appropriate application. The heartbeat sensor monitors the heartbeat of person A which is communicated via their pillow, their local host and a server, and then via a second local host to produce a visual and audible representation of heartbeat A in a pillow located with person B. At the same time, the heartbeat of person B is represented in the same manner at the pillow of person A.

Abstract: A non-contact electrocardiogram (ECG) sensor having an ECG electrode and guard electrode coupled to an electronic circuit that actively gain-corrects the electrocardiogram signal based on fringe capacitance signal and filters the gain-corrected signal based on a static charge reference signal. The compensation system first makes a gain correction for the preamplifier to address ECG electrode-to-subject motion and then removes any additive static common mode interference from motion-induced static charge generation.

Abstract: To make it possible to stably measure heartbeats even if seated persons physically differ and to measure the heartbeats of even a seated person other than a driver. A vehicle seat includes: a measuring device including a plurality of sensors that are provided in a seat back and that acquire body potentials of the seated person, and an arithmetic operation device that computes electrical signals to obtain an electrocardiographic signal of the seated person. The sensors are each capacitively coupled sensors. The sensor is arranged at a lower right position relative to the sensor and the sensor while facing a front surface of the seat back if a surface of the seat back facing the seated person is assumed as the front surface. Both sensors are arranged so that the seated person's heart is located in a zone if the zone is defined from the sensor and the sensor.

Abstract: The present disclosure generally relates to systems and method of a noninvasive electrocardiographic (ECG) technique for characterizing cardiac chamber size and cardiac mechanical function. A mathematical analysis of three-dimensional (3D) high resolution ECG data may be used to estimate chamber size and cardiac mechanical function. For example, high-resolution mammalian ECG signals are analyzed across multiple leads, as 3D orthogonal (X,Y,Z) or 10-channel data for 30 to 1400 seconds to derive estimates of cardiac chamber size and cardiac mechanical function. Multiple mathematical approaches may be used to analyze the dynamical and geometrical properties of the ECG data.

Abstract: Cardiac lead implantation systems, devices, and methods for lead implantation are disclosed. An illustrative cardiac lead implantation system comprises a mapping guidewire including one or more electrodes configured for sensing cardiac electrical activity, a signal analyzer including an analysis module configured for analyzing an electrocardiogram signal sensed by the mapping guidewire, and a user interface configured for monitoring one or more hemodynamic parameters within the body. The sensed electrical activity signal can be used by the analysis module to compute a timing interval associated with ventricular depolarization.

Abstract: A base cardiac electrogram signal at a base electrode is recorded for a predetermined amount of time. A plurality of cardiac electrogram signals at a plurality of electrodes other than the base electrode are recorded for the predetermined amount of time. The base cardiac electrogram signal is compared with each of the plurality of cardiac electrogram signals. The similarities between the base cardiac electrogram signal and each of the plurality of cardiac electrogram signals is determined. A specific area of cardiac tissue where the base electrode is positioned is mapped based at least in part on the determined similarities.

Abstract: Disclosed herein are various embodiments of methods, systems and devices for detecting atrial fibrillation (AF) in a patient. According to one embodiment, a hand-held atrial fibrillation detection device acquires an electrocardiogram (ECG) from the patient over a predetermined period of time. After acquiring the ECG from the patient, the device processes and analyzes the ECG and makes a determination of whether or not the patient has AF.

Abstract: The present invention provides a system and a method of monitoring and communicating biomedical data to a remote receiver. Specifically, the present invention provides a system and method that can monitor a biomedical-based electromagnetic field, e.g., heart rate variability (HRV) field, emitted from a human user (“sender”), and/or communicate the biomedical-based electromagnetic field to a remote receiver by measuring the biomedical-based electromagnetic field emitted from the sender, creating an electronic signal corresponding to the field and transmitting or broadcast and/or apply the signal to a remote receiver.

Abstract: Embodiments relate to devices and methods for monitoring, identifying, and determining risk of congestive heart failure (CHF) hospitalization. Methods include determining physiological values of a patient by electrocardiogram (ECG), bioimpedance, and 3-axis accelerometer, filtering the physiological values, comparing physiological values to baseline parameters and determining CHF risk. Devices include a 3-axis accelerometers, bioimpedance sensors, and an electrocardiogram, each capable of measuring patient physiological values, and one or more processors to receive the measured physiological values.

Abstract: Disclosed techniques include monitoring a physiological characteristic of a patient with a sensor that is mounted to an inner wall of a thoracic cavity of the patient, and sending a signal based on the monitored physiological characteristic from the sensor to a remote device.

Abstract: A bio-measurement data recording device has a seat which has a back surface made of a foam material, a seat surface, and a plurality of back surface sensors embedded in the back surface such that a plurality of leads for an electrocardiogram of a the person can be received. At least two seat surface sensors are embedded in the seat surface. A left hand grip is arranged such that it can be gripped by the person with the left hand and which has a left hand grip sensor or conducting a channel for the electrocardiogram, and a right hand grip is arranged such that it can be gripped by said person with the right hand and which has a right hand grip sensor for conducting a channel for the electrocardiogram. An evaluation unit is connected to the sensors and is configured to ascertain the electrocardiogram.

Abstract: A catheter has an inflatable assembly at its distal portion, including a containment chamber, an axial core and a plurality of longitudinally oriented partitions extending from the axial core to the wall of the chamber to divide the containment chamber into at least four inflatable sectors. Hydraulic valves are connected to respective sectors to enable selective inflation of the sectors by a fluid when the valves are connected to a source of the fluid, and at least one surface electrode is mounted on each of the sectors. When introduced into a heart chamber and diametrically opposed sectors are inflated the assembly is stably fixed against the walls of the heart chamber and readings can be obtained from the surface electrodes of the inflated sectors.

Abstract: A method for determining the signal quality of samples in a physiological signal, in particular an electrocardiogram (ECG) signal, is provided. A supra-threshold sample sum, a noise threshold crossing sum, or both are calculated in a noise detection window including the sample to be evaluated, and low signal quality is indicated if either or both of the sums exceed respective values. ECG beat detections can then be labeled as unreliable based on the determination of low signal quality for one or more samples between the detections.

Abstract: Apparatus and methods are described, included a method for detecting uterine contractions in a pregnant woman. The method includes sensing motion of the woman without contacting the woman, generating a signal corresponding to the sensed motion, and analyzing the signal to detect presence of labor contractions. Other applications are also described.

Abstract: An implantable medical device includes a sensor configured to generate an endocardial acceleration (EA) signal representative of activity of a patient's heart. The device further includes one or more circuits configured to identify within the EA signal at least one EA signal component corresponding to at least one peak of endocardial acceleration, and extract from the at least one EA signal component at least two characteristic parameters. The one or more circuits are further configured to generate a composite index based on a combination of the at least two characteristic parameters, determine a plurality of values of the composite index for a plurality of pacing configurations, and select a current pacing configuration from among the plurality of pacing configurations based on the plurality of values of the composite index.

Abstract: Methods, devices and kits for monitoring a physiological parameter using a portable physiological parameter detection and monitoring device. The devices include a removably adherable transparent film with an insulating upper surface that has two or more conductive elements within the film. The film can be adhered to a mobile device, such as a cell phone, to facilitate detecting a biological parameter such as a heart rhythm.

Abstract: Medical devices and methods for using medical devices are disclosed. An example mapping medical device may include a catheter shaft with a plurality of electrodes. The catheter shaft may be coupled to a processor. The processor may be capable of collecting a first set of signals from a first location, collecting a second set of signals from a second location, characterizing the first set of signals over a first time period, characterizing the second set of signals over a second time period, comparing the first set of signals to the second set of signals and matching a first signal from the first set of signals with a second signal from the second set of signals.

Abstract: Systems and methods of evaluating an association between a wireless sensor and a monitored patient include a plurality of peripheral electronic devices each having a wireless communication system and a sensor. A processor receives measured physiological parameter data from the peripheral electronic devices and establishes an association status between each of the peripheral electronic devices and the monitored patient based upon identified characteristics in the physiological parameter data.

Abstract: An arrangement may include a first system provided by a mobile device for processing ECG data representative of a beating heart. The mobile device may be adapted to execute a process for using at least one pattern to detect a notable finding in the ECG data and for sending the notable finding to a second system. The second system may be adapted to execute a process for analyzing the notable finding, for determining at least one new pattern to send to the mobile device, and for sending the at least one new pattern to the mobile device. The at least one new pattern may also include a rule that includes a set of conditions and an action to perform if the set of conditions is met.

Abstract: In a system and computer implemented method for mapping of an anatomic structure and bi-directional activation detection of electrograms such as atrial and/or ventricular electrograms, both positive and negative deflections of an electrogram signal are analyzed over an analysis time period of the signal. At least one characteristic of the electrogram signal is determined based at least in part on analyzing both positive and negative deflections of the signal over the analysis time period. The determined at least one characteristic of the atrial electrogram signal is then associated with a generated three-dimensional model of the anatomic structure.

Abstract: An electrocardiogram measuring apparatus includes: a population coefficient calculating unit which calculates: first population coefficients; and second population coefficients; a personal coefficient calculating unit which calculates: first personal coefficients; and second personal coefficients; and a lead deriving unit which: calculates first personal coefficients of a specific subject based on: a relationship between a magnitude of a ratio of the first population coefficients to the second population coefficients, and a magnitude of a ratio of the first personal coefficients to the second personal coefficients; and second personal coefficients of the specific subject which are calculated based on A leads of the specific subject, the A leads being acquired by electrocardiogram measurement; and synthesizes B leads of the specific subject by using the first personal coefficients of the specific subject.

Abstract: A method of generating a cardiac electrophysiology map includes receiving a reference biological signal and an electrical signal indicative of electrical activity at a location on a patient's heart. Using a graphical user interface, a practitioner designates at least two trigger point icons, one upward-pointing and one downward-pointing, on a graphical representation of the reference biological signal (e.g., a waveform). By pairing one upward-pointing icon with one downward-pointing icon, a plurality of triggering criteria are defined. Electrophysiology data points are captured and/or added to the electrophysiology map when the triggering criteria are satisfied.

Abstract: Methods, systems, and apparatus for detecting and/or validating a detection of a state change by matching the shape of one or more of an cardiac data series, a heart rate variability data series, or at least a portion of a heart beat complex, derived from cardiac data, to an appropriate template.

Abstract: A data collection unit obtains physiological data from a subject interface on a subject. The subject interface can be connected to the data collection unit. When the subject interface is connected to the data collection unit, subject interface contacts on the subject interface make contact with data collection unit contacts on the data collection unit. Some of the data collection unit contacts are for communicating physiological data from the subject interface to the data collection unit. Some of the contacts are for powering the data collection unit upon the subject interface being connected to the data collection unit and for powering down the data collection unit upon the subject interface being disconnected from the data collection unit.

Abstract: In general, in one aspect, a method is disclosed for determining information about a position of an object. The method includes: (i) causing current to flow between each of three or more sets of current-injecting electrodes on a first catheter inserted into an organ in a patient's body, the organ having a periphery (ii) in response to current flow caused by each set of current injecting electrodes, measuring an electrical signal at each of one or more measuring electrodes located on one or more additional catheters inserted into the organ in the patient's body and (iii) determining the position of each of one or more of the measuring electrodes on the additional catheters relative to the first catheter based on the measured signals from the one or more measuring electrodes.

Abstract: Disclosed is a detachable biological signal measuring pad that may conveniently measure biological signals such as a pulse or body temperature. The biological signal measuring pad includes an adhesive pad main body detachably adhered to a body, a biological signal detecting electrode provided on an adhesive surface of the main body adhered to the body, and a module chip including a memory card mounted on the main body so as to be connected with the electrode and storing biological signals measured in the electrode, and provided on a surface opposite to the adhesive surface.

Abstract: A biological signal measuring apparatus that is provided with an oscillatory wave detection apparatus, an oscillatory wave period measuring part, a group memory apparatus that is configured to collect the periodic data and to store the periodic data as a group signal, and a vibration frequency calculation apparatus. The vibration frequency calculation apparatus is provided with a section discrimination part configured to compare the group signal with a predetermined value to carry out a section discrimination, a section memory part configured to store to a plurality of sections, a weight coefficient memory part configured to store a weight coefficient, and an oscillatory wave period weighted average value calculation part.

Abstract: Using specialized cardiac catheters for image acquisition, features of the heart are readily identifiable on an ultrasound image, based on a previously generated electrical activation map of the heart. The electrical activation map is automatically registered with the ultrasound image using information obtained from position sensors in the catheters. Features identifiable on the electrical activation map, presented as points, tags, design lines, and textual identification, are projected into the plane of the ultrasound fan and overlaid on the ultrasound image, thereby clarifying the features that are visible on the latter.

Abstract: A heart monitoring system for a person includes one or more wireless nodes; and wearable appliance in communication with the one or more wireless nodes, the appliance monitoring vital signs.

Abstract: An apparatus for generating a synchronization signal based on an electrocardiogram signal of a body by obtaining the electrocardiogram signal, outputting a first peak signal when strength of the electrocardiogram signal becomes larger than that of a reference signal, and generating a first synchronization signal depending on the first peak signal is provided.

Abstract: Methods and apparatus combine patient measurement data with demographic or physiological data of the patient to determine an output that can be used to diagnose and treat the patient. A customized output can be determined based the demographics of the patient, physiological data of the patient, and data of a population of patients. In another aspect, patient measurement data is used to predict an impending cardiac event, such as acute decompensated heart failure. At least one personalized value is determined for the patient, and a patient event prediction output is generated based at least in part on the personalized value and the measurement data. For example, bioimpedance data may be used to establish a baseline impedance specific to the patient, and the patient event prediction output generated based in part on the relationship of ongoing impedance measurements to the baseline impedance. Multivariate prediction models may enhance prediction accuracy.

Abstract: A system and method for performing off-line analysis of cardiac electrogram data, comprising: retrieving an electrogram from a memory location; identifying a first-channel group of candidate beats from at least a first channel of the electrogram; and identifying a second-channel group of candidate beats from at least a second channel of an electrogram. For each first-channel beat candidate near a second-channel beat candidate, the amplitude of the first-channel beat candidate is compared with the amplitude of a previous beat and the amplitude of a next beat on the first electrogram channel, and first-channel beat candidates that are outside of a first pre-determined range from either the previous or next beat are removed. Then first-channel beat candidates that are outside of a second pre-determined range from either the previous or next beat candidate are removed.

Abstract: Sensing is carried out from locations considerably removed from the stomach. Cooperating sensor electronics are placed at each of two wrists of the patient. The potential discomfort and inconvenience of an abdominal patch are reduced or eliminated, and alternative power sources become available.

Abstract: A computer-implemented method for recognizing a user's activity pattern includes pre-storing activity data in a computer system, automatically determining locations of one or more sensors on a user's body, obtaining time series of measured activity parameters by the one or more sensors, automatically segmenting the time series of measured activity parameters into two or more activity periods, determining a spatial range of the movement in an activity period, and recognizing an activity in the activity period based at least in part on the measured activity parameters and the pre-stored activity data.

Abstract: A physiological signal measurement apparatus is capable of automatically adjusting a measure position and suitable for installed on a support element to measure a physiological signal of a user. The physiological signal measurement apparatus includes a movable element, a physiological signal sensing element, a pressure sensing unit and a microcontroller unit. The movable element has a first pressure. The user exerts a second pressure on the physiological signal sensing element, and exerts a third pressure on the support element. The pressure sensing unit senses the first pressure, the second pressure and the third pressure to generate a first pressure signal, a second pressure signal and a third pressure signal. The microcontroller unit receives the physiological signals and the pressure signals, and controls the movable element by the pressure signals and the physiological signals, in order to increase the quality of signal measurement.

Abstract: A noise processing apparatus measures a first potential difference signal, between a first electrode and a second electrode that is used as a reference electrode, and measures a second potential difference signal, between the second electrode and a third electrode that is arranged on the steering unit in the apparatus. The apparatus calculates the difference between the intensities of the first potential difference signal and the second potential difference signal calculated at the predetermined intervals. The apparatus corrects the first potential difference signal or the second potential difference signal by using the calculated difference such that the intensities of the first potential difference signal and the second potential difference signal are canceled out.

Abstract: Systems, methods, and computer-readable media for managing healthcare environments are provided. In embodiments, a first waveform tracing for data received from one or more medical devices for a first individual is displayed. A second waveform tracing for data received from one or more medical devices for a second individual is displayed. In response to the determination to hide the first waveform tracing, only displaying the second waveform tracing.

Abstract: A method including: measuring signals at one or more catheter electrodes in response to electrical activity in a heart cavity and collecting additional data signals; defining a template set including information related to the additional data signals; computing criteria for each of the additional data signals based on a comparison of the additional data signals and the template set; synchronizing the measured signals with one another by calculating a single synchronization offset that is a time value based on the computed criteria and the difference between a marker in the template set and a point in the additional data signals; selecting a subset of the synchronized signals by determining whether to include the signals for a heartbeat in the subset based on the computed criteria; and determining physiological information at multiple locations of the endocardium surface based on the measured signals by processing the selected subset.

Abstract: A sensor for contactless electrocardiographic measurement of a person has at least one electrically conductive, planar electrode having a measurement surface facing the person and a connection surface facing away from the person. An electrical terminal for connection with a measurement apparatus is spaced from the connection surface such that the connection surface is only placed in electrical connection with the terminal when pressure of a required magnitude is applied to the measurement. The electrical connection may be achieved by a switching contact disposed between the electrode and the terminal which is brought into contact with both the electrode and the terminal when the electrode is deflected toward the terminal by the pressure. A compressible material is disposed between the electrode and the terminal to allow tuning of the pressure required to achieve electrical contact.

Abstract: An electrode structure for use with a monitoring system. A thin flexible body of an electrode material comprising conductive rubber is provided with projections extending externally to a working surface. According to this construction of the working surface of the electrode only the projections make a contact to the recipient's skin. When the projections are provided with a small cross-section, the constant electrode-skin contact is ensured due to the resiliency of the electrode material.

Abstract: Apparatus and methods are described, including a method for treating a clinical episode. The method comprises sensing at least one parameter of a subject without contacting or viewing the subject or clothes the subject is wearing, analyzing the parameter, detecting the clinical episode at least in part responsively to the analysis, and responsively to detecting the clinical episode, treating the clinical episode using a device implanted in the subject. Other applications are also described.

Abstract: Systems and methods to assist in locating the focus of an atrial fibrillation include the association of atrial fibrillation cycle length values and statistics relating thereto with temporal locations on an electrogram of a given electrode, and/or the coordination of electrode locations with respective the spectral analyses of electrogram signals and further parameters and statistics relating thereto. Ablation therapy can proceed under guidance of such information.

Abstract: A non-contact cardiac mapping method is disclosed that includes: (i) inserting a catheter into a heart cavity having an endocardium surface, the catheter including multiple, spatially distributed electrodes; (ii) measuring signals at the catheter electrodes in response to electrical activity in the heart cavity with the catheter spaced from the endocardium surface; and (iii) determining physiological information at multiple locations of the endocardium surface based on the measured signals and positions of the electrodes with respect to the endocardium surface. Related systems and computer programs are also disclosed.

Abstract: Interaction between a portable apparatus and a personal exercise area is disclosed. A method comprises: transferring wirelessly information between a personal exercise area and a portable apparatus; detecting proximity of the portable apparatus to the personal exercise area by utilizing the transferred information; and configuring the portable apparatus in relation to an exercise performed within the personal exercise area by a user of the portable apparatus.