Having Means For Metering Material Flow To Or From Body Patents (Class 604/207)
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Patent number: 7018365Abstract: A threaded syringe provides a mechanism by which a clinician can deliver a viscous fluid through a relatively small lumen and can obtain tactile or audible feedback of delivery. The threaded syringe allows for delivery of more viscous fluids with less force and/or allows for more controlled delivery. The syringe includes a syringe barrel and a sliding member positioned on the proximal end of the syringe barrel. The sliding member has a first threaded hole and a second hole. The sliding member is slidable on the syringe barrel between a first position at which the first threaded hole is aligned with the syringe barrel for precise delivery of a material from the syringe and a second position at which the second hole is aligned with the syringe barrel for filling of the syringe or to stop bleed out.Type: GrantFiled: August 16, 2002Date of Patent: March 28, 2006Assignee: Micro Therapeutics, Inc.Inventors: Brian M. Strauss, Brock H. Smith, Brian Canfield, Amanda Conner, Douglas R. Hayman, Ed Olsen
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Patent number: 6986758Abstract: A device for administering an injectable product in doses including a dosage reservoir from which a product dosage is administered, a storage reservoir for storing the product, a transfer conveyor for conveying the product dosage from the storage reservoir into the dosage reservoir, an evacuator for evacuating the dosage reservoir, and a dosing and activating mechanism for performing a dosing movement for selecting the product dosage, a conveying movement for activating the transfer conveyor and an evacuating movement for activating the evacuator.Type: GrantFiled: December 17, 2003Date of Patent: January 17, 2006Assignee: TecPharma Licensing AGInventor: Frank Schiffmann
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Patent number: 6945961Abstract: An injection device having an incremental clicking mechanism providing the user with an indication of the number of doses being set. For handling different types of medicaments having different dose volumes in the same type of injection device it is beneficial to provide an additional clicking mechanism which is easy changeable. The clicking mechanism is preferably a curved track provided between the dose setting member and a non-rotatable clicker element.Type: GrantFiled: July 1, 2003Date of Patent: September 20, 2005Assignee: Novo Nordisk A/SInventors: Thomas Dedenroth Miller, Claus Schmidt Moller, Steffen Hansen
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Patent number: 6942646Abstract: An injection device for injection of a medicament from a first medicament cartridge (40) is disclosed. The injection device comprises a drive mechanism (42) for selectively dispensing the medicament from the first medicament cartridge (40), a dial dose mechanism (12, 14) by which a user may determine a required dose of medicament to be dispensed, an electronic control unit for controlling the operation of the drive mechanism (42) in response to the dial dose mechanism (12, 14) and a display panel (10).Type: GrantFiled: December 21, 2001Date of Patent: September 13, 2005Assignee: DCA Design International LimitedInventors: Christopher Nigel Langley, Shane Alistair Day, Robert Frederick Veasey, Robert Woolston
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Patent number: 6932794Abstract: A medication delivery pen is provided including a leadscrew having a plurality of threads; a driver coaxially disposed about at least a portion of the leadscrew; a dosing ring non-rotatably disposed on the driver, the dosing ring also being slidable along the driver; and, a dose knob coaxially disposed about the dosing ring. At least one tooth is formed on one of the dose knob and the dosing ring, and at least one groove is formed on the other of the dose knob and the dosing ring, with the groove being formed to receive the tooth. The dosing ring is selectively movable relative to the dose knob from a first position where the tooth and the groove are spaced apart to a second position where the tooth is received within the groove, the dosing ring being rotatable with the dose knob with the dosing ring being in the second position.Type: GrantFiled: April 3, 2003Date of Patent: August 23, 2005Assignee: Becton, Dickinson and CompanyInventors: Lucio Giambattista, Antonio Bendek
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Patent number: 6899699Abstract: The present invention relates to a dose setting and expelling device comprising a drive member and a dose setting mechanism which simultaneously sets a given dose and stores the energy necessary for a subsequently driving the drive member in order to expel a dose of medicine from an injection device. According to the invention the dose setting mechanism allows adjustment in both directions, such that a given set dose can be reduced or cancelled by reversing the input motion, typically by rotating a setting member backwardly, this in contrast to the known devices which either requires an additional release mechanism or which cannot be reversed at all.Type: GrantFiled: January 2, 2002Date of Patent: May 31, 2005Assignee: Novo Nordisk A/SInventor: Christian Enggaard
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Patent number: 6837876Abstract: A device for administering an injectable product in doses, wherein the device includes a casing, a reservoir for the product, a piston, an advancing element which moves the piston a selected path length, and a dosing mechanism including a number of dosing bodies and a dosing element operable to move the dosing bodies, wherein the path length is selected by the dosing element moving at least one dosing body between the piston and the advancing element.Type: GrantFiled: October 16, 2002Date of Patent: January 4, 2005Assignee: TecPharma Licensing AGInventors: Christoph A. Bally, Stefan Jost
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Publication number: 20040260247Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve having a helical thread of a first lead, and a two-part piston rod. The two-part piston rod may include an outer part having a helical thread of a second lead and an inner part having a helical thread of a third lead. In such an embodiment, the first lead of the thread of the dose dial sleeve may be equal to the sum of the second lead of the thread of the outer part of the piston rod and the third lead of the thread of the inner part of the piston rod.Type: ApplicationFiled: March 2, 2004Publication date: December 23, 2004Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
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Publication number: 20040249348Abstract: A dose dial and drive mechanism for use in a drug delivery device having a housing, a dose dial sleeve, a piston rod, a drive sleeve threadedly connected to the piston rod, a reset sleeve, which is located between the drive sleeve and the housing, and a dose display. When the dose dial sleeve travels towards the second end of the housing the reset sleeve is carried with the dose dial sleeve towards the second end of the housing resetting the dose display to a zero position and when the dose dial sleeve and/or the reset sleeve travels towards the first end of the housing, the dose dial sleeve and/or reset sleeve engage(s) with the drive sleeve thus advancing both the drive sleeve and the piston rod towards the first end of the housing.Type: ApplicationFiled: March 22, 2004Publication date: December 9, 2004Inventors: Steven Wimpenny, David Aubrey Plumptre, Robert Frederick Veasey
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Medication dispensing apparatus configured for rotate to prime and pull/push to inject functionality
Publication number: 20040236285Abstract: A medication dispensing apparatus having a manually operable plunger axially shiftable relative to the apparatus housing. The plunger is pullable relative to the housing in a proximal direction to cock the apparatus, and when the plunger is then manually pushed back toward the housing, a piston within a medicine container of the apparatus is shifted to force medication from a needle assembly at the distal end of the apparatus. The medication dispensing apparatus also includes a priming mechanism which is operated by rotating an externally accessible driver portion to prime the apparatus for use, which priming can be performed whether or not the apparatus is in a cocked state.Type: ApplicationFiled: January 9, 2004Publication date: November 25, 2004Inventors: Mark James Fisher, Traci Jo Barron, Scott Alan Massing, Iain Roberts -
Patent number: 6811548Abstract: Materials delivery devices, e.g. for drugs etc. (FIGS. 1-7) or body fluids (FIGS. 8-12), have administration means of piston-and-cylinder (100; 300) or peristaltic rollers and tube (546, 565; 646, 665; 746, 765; 846, 865; 946, 965) type, and intermittently incremental drive transmission means of cooperating toothed rack (143) or wheel (345, 445; 545; 645; 745; 845; 945) and deflectable biassed pawl (153, 156; 343, 356; 453, 456; 553, 556; 653, 656; 753, 756; 853, 856; 953, 956) type driven by pulsed reciprocating solenoid action (110; 310; 410; 510). Portable patient-wearable drug delivery devices (10; 30; 40; 50) can use pre-loaded cartridges (120; 320; 420; 520) and have solenoid drive (130) for needle-entry and battery-powered electronic control, etc. Intravenous infusion pumps (60; 70; 80; 90) can operate relative to body fluid reservoirs or for body fluid transfers.Type: GrantFiled: September 30, 1998Date of Patent: November 2, 2004Inventor: Peter Jeffrey
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Patent number: 6796970Abstract: A dose setting device for a delivery system has a piston rod (6, 9) which successively presses a piston (2) into a cylinder ampoule (1). Doses are set by rotating a second part (9) of the piston rod (6, 9) in relation to a first part (6). The two parts are connected by mating threads so that the total length of the piston rod (6, 9) is increased proportional to the angle of rotation, and a point (18) on the second part is moved away from a stop position fixed in relation to a housing (5) The set dose is delivered when the point (18) is moved back to the stop position. The first part (6) can be axially displaced but not rotated in the housing (5), and the second part (9) can both rotate and be axially displaced. The first part (6) is maintained in abutment with the piston (2) and the second part (9) is coupled to be rotated by a dose setting wheel (20).Type: GrantFiled: June 4, 1998Date of Patent: September 28, 2004Assignee: Novo Nordisk A/SInventors: Lars Peter Klitmose, Henrik Andersen, Preben Broskov Nielsen, John Thrane Hansen
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Publication number: 20040186442Abstract: A product dispensing apparatus including a reservoir module, a dosing module and a dose setting member. The reservoir module includes a front casing section, a block, a first connector, a piston, and a piston rod moveable in a dispensing movement and against the dispensing movement, and including a return block engageable with the block, wherein engagement between the block and the return block prevents the piston rod from moving against the dispensing movement. The dosing module includes a rear casing section, including a second connector which is engageable with the first connector to form a detachable connection between the reservoir module and the dosing module, and a dosing and drive device. The dose setting member engages the piston rod such that it is moveable together with and in the same direction as the piston rod during the dispensing movement and is moveable relative to the piston rod against the dispensing movement.Type: ApplicationFiled: January 29, 2004Publication date: September 23, 2004Inventors: Roney Graf, Fritz Kirchhofer
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Publication number: 20040186441Abstract: An administering apparatus including a front casing section, a rear casing section connectable to the front casing section, a driven member carried by at least one of said casing sections for performing a delivery movement, a dose setting member for performing a dosing movement relative to the driven member to select said product dosage, and a dosing and drive device moveable rotationally about a rotational axis and translationally relative to the front casing section, wherein, when connecting the casing sections, the dosing and drive device is coupled to the driven member and the dose setting member such that a rotational movement of the dosing and drive device causes the dosing movement of the dose setting member and a translation movement of the dosing and drive device causes the delivery movement of the driven member, wherein at least one axial guide is formed on one of the casing sections and at least one engagement element is formed on the other of the casing sections such that when connecting the casinType: ApplicationFiled: January 29, 2004Publication date: September 23, 2004Inventors: Roney Graf, Fritz Kirchhofer
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Publication number: 20040176729Abstract: Injection devices are known for the self administration of medicament by patients in which the medicaments is typically contained within a cartridge located within the injection device. It is a problem that injection devices should be small enough to fit into a jacket pocket or a hand bag without difficulty. Also, the injection device must be of a size that enables a piston or similar used to drive a cartridge bung within the cartridge to be moved both to a maximum dispense position within the cartridge and to be fully withdrawn from the cartridge to allow for replacement of the cartridge.Type: ApplicationFiled: September 15, 2003Publication date: September 9, 2004Inventors: Christopher Nigel Langley, Robert Woolston
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Publication number: 20040162528Abstract: An embodiment of the present invention provides an apparatus for setting a dose of a drug in a syringe having a plunger, comprising an outer housing and an inner housing adapted for encircling the syringe, such that the inner housing is positioned within the outer housing to set the dose of the drug. In an embodiment, the apparatus further comprises a dosage indicator disposed on the inner housing and the outer housing further comprises an opening for viewing the dosage indicator.Type: ApplicationFiled: February 14, 2003Publication date: August 19, 2004Applicant: Xcel Pharmaceuticals, Inc.Inventors: Michael W. Horvath, David F. Jensen, Mark R. Sponsel, Joseph P. Rossi, Gregory D. Malone
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Patent number: 6770056Abstract: A device for dispensing a measured dose of liquid from an attached container which container has an elongate casing defining a dispensing cylinder, one end of the casing being adapted for mounting on the container. A plurality of dose indications are provided on the external surface of the casing so that a dose may be pre-selected by moving a dose setting collar along the casing. The collar has a stop engageable with a selected one of a multiplicity of recesses on the casing to secure the collar at the required position. A plunger having a piston co-operating with a cylinder defined by the casing is movable to lift the piston from said one end of the casing until the piston abuts the dose setting collar so charging the dispenser. Depression of the plunger to move the piston back to said one end dispenses the selected dose from an outlet port.Type: GrantFiled: August 22, 2002Date of Patent: August 3, 2004Assignee: Novartis AGInventors: Phil T. Price, Stephanie Bley, Bernard Sams
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Patent number: 6764469Abstract: A syringe including a barrel for retaining fluid and having a dispensing port for permitting fluid flow therethrough. A plunger is received within the barrel and is axially moveable relative thereto for controlling fluid flow through the dispensing port. A dosing indicator is carried by the plunger and includes indicia thereon collectively representing a dosing range of the fluid based upon a correlation between the indicia and a therapeutic treatment variable for a preselected group of patients. The indicia cooperate with the plunger and barrel for measuring a medically correct dose of the fluid to be administered to a patient from the group.Type: GrantFiled: August 2, 2002Date of Patent: July 20, 2004Inventor: James B. Broselow
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Publication number: 20040097883Abstract: A pen delivery device and a procedure for administering parathyroid hormone is provided to allow for the priming and injection of a single predetermined dose. The method is a three-step method using visual indicators to set the priming and injectable dose deliveries. The device is made of a minimal number of parts, which include a housing, a dose knob, a generally cylindrical disengaging assembly located within the proximal end of the dose knob, and an externally threaded drive stem. The pen device further includes a mechanism that prevents the user from dialing up a dosage greater than that remaining in the cartridge.Type: ApplicationFiled: March 19, 2003Publication date: May 20, 2004Inventor: Michael Joseph Roe
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Publication number: 20040082918Abstract: A drug administration system includes a cradle attached about an intravenous injection port having a flange extending therefrom. The cradle supports first drug administration information in the nature of machine and human readable code, for example, barcode. A syringe including a needle includes a flange extending from the syringe. The syringe supports second drug administration information in machine and/or human readable form. A scanner module is constructed to slidably receive the flange of the cradle and syringe whereby the syringe needle is aligned with the intravenous injection port. The module may be provided with an electronic scanning system for identifying the first and second drug administration information, as well as determining the amount of the drug being administered from the syringe to the injection port by monitoring movement of the syringe plunger. The information and data may be stored within the module for uploading to a remote location.Type: ApplicationFiled: October 21, 2003Publication date: April 29, 2004Applicant: DocuSys, Inc.Inventors: Robert F. Evans, Michael F. Burrow
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Patent number: 6726661Abstract: Described is an electronic injection device wherein an electronic circuit is designed to work in two alternative modes: an air shot mode and a dose injection mode. When working in the air shot mode a small predetermined air shot dose is pressed out from the ampule when the injection button is actuated. When working in the injection mode, a dose set by operation of the dose setting means is injected by operation of the injection button. The electronic injection device is normally working in the air shot mode but shifts to work in the dose injection mode when it receives a signal indicating that the dose setting means has been operated. The circuit returns to its air shot mode when receiving a signal indicating that the set dose has been injected. This signal can originate either from a switch indicating that the protection cap is mounted or from a switch indicating that the injection button has been pressed.Type: GrantFiled: December 10, 2002Date of Patent: April 27, 2004Assignee: Novo Nordisk A/SInventors: Jens Munk, Denmark Denmark Aasmul, Henrik Ljunggreen, Lars Hofmann Christensen
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Publication number: 20040073173Abstract: A medicament delivery device is disclosed having dose dial means 6,8 to determine a quantity of medicament to be delivered. The medicament delivery device is also provided with selection means to select whether the quantity of medicament to be delivered is determined as a multiple of a first quantum of units or as a multiple of a second quantum of units.Type: ApplicationFiled: December 5, 2003Publication date: April 15, 2004Inventors: Christopher Nigel Langley, Shane Alistair Day, Robert Frederick Veasey, Robert Woolston
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Patent number: 6716198Abstract: An injection device for injecting set doses from an ampoule (2) mounted in the device, which doses are set by operation of a dose setting button (7) by which operation elastic torsion rods (14) positioned parallel with the longitudinal axis of the device are twisted. By the dose setting a torque is transmitted from the dose setting button (7) to the rods (14) through gear transmissions comprising a toothing (11) carried by a tubular (8) part coupled to the dose setting button (7) to rotate with this button. The toothing (11) engages pinions (13) fixed to the proximal ends of the torsion rods (14), which are made from a super elastic material, which can stand a deformation larger than 2% without being permanently deformed.Type: GrantFiled: May 11, 2001Date of Patent: April 6, 2004Assignee: Novo Nordisk A/SInventor: Andre Larsen
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Publication number: 20040064104Abstract: An injection device comprising an incremental clicking mechanism providing the user with an indication of the number of doses being set. For handling different types of medicaments having different dose volumes in the same type of injection device it is beneficial to provide an additional clicking means which is easy changeable. In this way different dose volumes can be dispensed by the same type of injection devices simply by utilizing different clicking means. The clicking means is preferably a curved track provided between the dose setting member and a non-rotatable clicker element.Type: ApplicationFiled: July 1, 2003Publication date: April 1, 2004Inventors: Thomas Dedenroth Miller, Claus Schmidt Moller, Steffen Hansen
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Publication number: 20040059299Abstract: An injection device for injection of set doses of medicine from a cartridge, in which syringe a dose is set by screwing a nut up along a threaded piston rod, whereby a dose setting drum, which carries on its cylindrical surface along a helix a scale of which a number corresponding to the set dose is shown in a window in the housing of the syringe, and an injection button, which is elevated over the end of the syringe, are moved axially a distance which is larger than the axial movement of the nut. A gear wheel gear transmission is established between the nut and the injection button.Type: ApplicationFiled: September 22, 2003Publication date: March 25, 2004Inventor: Claus Schmidt Moller
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Publication number: 20040030297Abstract: The present invention relates to a device for guiding a rod-shaped output member (401) of an injection device with an exchangeable cartridge containing injection liquid, the rod-shaped output member (401) having grooves (402) extending in lines in the axial direction on the outer circumference and, between the grooves (402), lines (403) with a structured surface, a guide element made up of at least two parts being provided, both parts of which are of annular shape and each have grooves (301, 302) extending in lines in the axial direction on their inner circumference and, between the grooves, lines (303, 304) with a structured surface, the two parts of the guide element being turned relative to one another in a working position in such a way that the grooves of the one part are continued in the axial direction by the structured surface of the other part.Type: ApplicationFiled: May 14, 2003Publication date: February 12, 2004Inventor: Thomas Hegewald
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Publication number: 20040030296Abstract: An injection device for injection of a medicament from a first medicament cartridge (40) is disclosed. The injection device comprises a drive mechanism (42) for selectively dispensing the medicament from the first medicament cartridge (40), a dial dose mechanism (12, 14) by which a user may determine a required dose of medicament to be dispensed, an electronic control unit for controlling the operation of the drive mechanism (42) in response to the dial dose mechanism (12, 14) and a display panel (10).Type: ApplicationFiled: June 6, 2003Publication date: February 12, 2004Inventors: Christopher Nigel Langley, Shane Alistair Day, Robert Frederick Veasey, Robert Woolston
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Publication number: 20040024368Abstract: A syringe including a barrel for retaining fluid and having a dispensing port for permitting fluid flow therethrough. A plunger is received within the barrel and is axially moveable relative thereto for controlling fluid flow through the dispensing port. A dosing indicator is carried by the plunger and includes indicia thereon collectively representing a dosing range of the fluid based upon a correlation between the indicia and a therapeutic treatment variable for a preselected group of patients. The indicia cooperate with the plunger and barrel for measuring a medically correct dose of the fluid to be administered to a patient from the group.Type: ApplicationFiled: August 2, 2002Publication date: February 5, 2004Inventor: James B. Broselow
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Patent number: 6685678Abstract: A drug administration system includes a cradle attached about an intravenous injection port having a flange extending therefrom. The cradle supports first drug administration information in the nature of machine and human readable code, for example, barcode. A syringe including a needle includes a flange extending from the syringe. The syringe supports second drug administration information in machine and/or human readable form. A scanner module is constructed to slidably receive the flange of the cradle and syringe whereby the syringe needle is aligned with the intravenous injection port. The module may be provided with an electronic scanning system for identifying the first and second drug administration information, as well as determining the amount of the drug being administered from the syringe to the injection port by monitoring movement of the syringe plunger. The information and data may be stored within the module for uploading to a remote location.Type: GrantFiled: March 21, 2001Date of Patent: February 3, 2004Assignee: Docusys, Inc.Inventors: Robert F. Evans, Michael F. Burrow
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Publication number: 20040019333Abstract: An administering apparatus with a dosage display, including a casing, a reservoir for a fluid product, a driven device which acts on the product, a dosing means for selecting a product dosage to be delivered which includes a dosage scale including a number of dosage marks axially spaced from each other, and a drive device coupled to the driven device for driving the driven device, the drive device performing a delivery stroke from an initial position, in a drive direction, to a delivery stopper, the length of the delivery stroke counter to the drive direction being limited by selecting the product dosage using the dosing means, wherein the casing is transparent at least in an area overlapping the dosage scale, and wherein the drive device forms an indicator to the dosage scale in order to indicate the initial position of the drive device.Type: ApplicationFiled: July 17, 2003Publication date: January 29, 2004Inventors: Roney Graf, Fritz Kirchhofer
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Patent number: 6673049Abstract: The present invention provides an injection device and an actuator for an injection device, wherein the actuator comprises a generally rod-shaped driven member having a structured surface portion, a counter component having a structured surface portion engaging the structured surface portion of the driven member, whereby the driven member is movable by the counter component, and a spreader bushing for spreading open the counter component by a movement relative to the counter component, thereby allowing the driven member to shift freely, wherein the spreader bushing is selectively movable with and relative to the counter component.Type: GrantFiled: February 15, 2001Date of Patent: January 6, 2004Assignee: Disetronic Licensing AGInventors: Edgar Hommann, Stefan Jost
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Patent number: 6666849Abstract: A self-use medical injector has a knob at the rear end of a barrel which is rotated from a zeroed position to set the dose and which rotates back again, to the zeroed position, when the injector is fired. A scale is provided on the knob (2) or barrel (1) and a datum mark or indicator on the barrel or knob co-operates with the scale. There is a raised stud (3, 11, 12, 16) providing the indicator or the zero mark of the scale. An annular member (4, 10, 14, 17) fitted over the knob if the stud is on the barrel or over the barrel if the stud is on the knob, has a projection (9, 12, 15, 18) which is registered with a mark on the scale corresponding to the required dose. This projection abuts the stud when the knob is rotated and thus sets the knob for the correct does.Type: GrantFiled: October 2, 2000Date of Patent: December 23, 2003Assignees: Owen Munford Limited, Eli Lilly and CompanyInventors: Jeremy Marshall, Paul E Jansen
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Patent number: 6663602Abstract: An injection device for injection of set does of medicine from a cartridge has a nut that is screwed up along a threaded piston rod during a dose setting operation. The nut is screwed along the piston rod by rotating a dose setting drum. An injection button is coupled to the piston rod with a gear wheel transmission. Axial movement of the injection button causes a corresponding axial movement of the piston rod until the nut engages an abutment in the housing.Type: GrantFiled: June 14, 2001Date of Patent: December 16, 2003Assignee: Novo Nordisk A/SInventor: Claus Schmidt Møller
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Publication number: 20030216696Abstract: The present invention relates to a setting element for an injection device, in which a dose of a liquid to be injected can be set in predetermined steps by moving a setting element a corresponding distance, the movement of the setting element follows a trajectory with predetermined locking points along a cam, and the trajectory can be traveled in two directions of movement, by virtue of the fact that the trajectory, at each point, has finite gradients in both directions.Type: ApplicationFiled: May 14, 2003Publication date: November 20, 2003Inventor: Thomas Hegewald
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Patent number: 6648850Abstract: A gas-powered, durable, needle-less hypodermic jet injection device (10, 110) includes a hand-held injector (12, 112) which provides a volume of liquid medication to be injected, an injection orifice, and an injection piston. Forceful movement of the injection piston causes an injection jet of medication to be expelled from the injection orifice. The injection device also includes a hermetically sealed gas pressure cartridge (28) which is opened in preparation to effecting a jet injection, and which powers the jet injection, but from which pressurized gas is not allowed to flow in volume until a user of the device shifts a valving spool (24).Type: GrantFiled: June 8, 2001Date of Patent: November 18, 2003Assignee: Bioject, Inc.Inventor: Sergio Landau
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Publication number: 20030187405Abstract: A device for administering an injectable product in doses including a casing, a reservoir for the product, a piston which displaces product towards a reservoir outlet and out of the reservoir when it slides in an advancing direction, a drive member which may be slid along a sliding axis, thereby pushing the piston in the advancing direction, and a dosing member which is mounted in the casing and may be slid, preferably rotatably, about the sliding axis of the drive member for setting a product dose, wherein a bearing surface between the dosing member and the casing is lubricated and at least one lubricating agent reservoir is provided on the bearing surface.Type: ApplicationFiled: March 25, 2003Publication date: October 2, 2003Inventors: Stephan Gatti, Thomas Gurtner
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Publication number: 20030176841Abstract: The present invention relates to a medicament delivery device such as an injector for self-administration of a medicament. Those using such devices are often infirm or have impaired vision There is accordingly a dead for a medicament delivery device in which an amount of a dosage of medicament to be delivered can be selected relatively quickly by the firm and infirm alike and in which the amount of the dosage may readily be controlled and determined. Also there is a need to display the amount of the dialled dosage of medicament on the rotatable knob in figures sufficiently large and clear to be legible by those having a degree of impaired vision.Type: ApplicationFiled: February 28, 2003Publication date: September 18, 2003Applicant: DCA Design International LimitedInventor: Michael Cameron Bainton
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Patent number: 6613019Abstract: A liquid medication delivery device for, and a method of, delivering medication from a cartridge having a moveable piston at one end is disclosed. The piston has a first wall face that contacts the liquid in the cartridge and a second wall for engaging a piston rod that drives the piston. The first and second walls are moveable but the second wall tends to move more quickly then the first during administration of a dose of medication from the cartridge. To compensate for this difference in movement between the first and second wall faces, the rod first moves a distance corresponding to the amount that the first wall face must move to deliver the desired dose and then it continues to move past this position by an amount known as an overshoot distance. It is then retracted by a distance equal to the overshoot distance.Type: GrantFiled: July 13, 2001Date of Patent: September 2, 2003Assignee: Novo Nordisk A/SInventor: Jens Aage Munk
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Publication number: 20030158523Abstract: Injector device, and method for its operation, for containers of syringe type, comprising a barrel of axially roughly constant cross-section, a front opening and at least one movable wall inserted in the barrel for displacement of a container content, the injector comprising a) a housing or housing part arranged to receive the container at least axially stationary, b) an integral or composite piston rod arrangement operable to displace the container movable wall at least in the forward direction and c) a track system for controlling or sequencing the piston rod movements, the track system comprising at least one cooperating track and follower, the cooperating track and follower being arranged stationary with respect to the housing and the piston rod respectively, or vice versa, and in cooperation allowing at least one forward for the piston rod. The track system comprises arrangements initiation, dose setting and expulsion of container content.Type: ApplicationFiled: March 26, 2003Publication date: August 21, 2003Inventors: Birger Hjertman, Rudolf Cseke
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Patent number: 6585698Abstract: A medication delivery pen includes a housing having opposing proximal and distal ends. An actuator is disposed in the proximal end of the housing for setting and administering a dosage of medication. The pen also includes a medication-containing cartridge assembly having a cartridge with a pierceably sealed distal end, an open proximal end removably attachable to the distal end of the housing, and a piston in sliding fluid tight engagement within the cartridge. A drive mechanism is coupled between the actuator and the cartridge to exert an axial force on the piston to inject the set dosage of medication. The actuator triggers the drive mechanism to administer the injection of medication held in the cartridge. A processor is coupled to the actuator to determine a value equal to the dosage set by the actuator. A memory device is coupled to the processor to store at least the dosage value determined by the processor.Type: GrantFiled: November 1, 1999Date of Patent: July 1, 2003Assignee: Becton, Dickinson & CompanyInventors: Jay D. Packman, John E. Burbank, III, Antonio A. Bendek, Robert C. Uschold
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Patent number: 6585699Abstract: A drug delivery device comprising a housing (1) with a drug container (2) being provided with delivering means comprising a piston (5) for expelling a drug (4) from the drug container (2). The housing (1) further comprising a displaceable piston rod (6) abutting the piston (5) of the drug container (2) and rotating means being in engagement with the piston rod (6), said rotating means being provided with a one-way mechanism. The one-way mechanism comprises a helical spring (12) wound tightly around an axle (11), one end of said helical spring (12) being fixed in relation to the housing (1), the other end of the helical spring (12) being in a free state.Type: GrantFiled: March 30, 2001Date of Patent: July 1, 2003Assignee: NNA/SInventors: Henrik Ljunggreen, Jens Ulrik Poulsen, Soren Aasmul, Lars Hofmann Christensen, Jens Moller-Jensen, Peter Moller-Jensen
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Patent number: 6582404Abstract: A limiting mechanism which prevents the setting of a dose, which exceeds the amount of liquid left in a cartridge of an injection device, is disclosed. The injection device is the type where a dose is set by rotating a dose setting member relative to a driver and away from a fixed stop in the injection device. The dose setting member interfaces the driver such that the dose setting member can be rotated in one direction without rotating the driver. The dose is injected by rotating back the dose setting member which during the backward rotation carries the driver with it. Rotating the driver causes the piston rod to move forward inside the cartridge and expel some of the liquid contained in the cartridge. The driver is provided with a track having a length which is related to the total amount of liquid in the cartridge and which track is engaged by a track follower coupled to the dose setting member to follow rotation of this dose setting member.Type: GrantFiled: September 6, 2000Date of Patent: June 24, 2003Assignee: NNA/SInventors: Peter Christian Klitgaard, Steffen Hansen, Bo Radmer, Claus Schmidt Møller
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Patent number: 6579269Abstract: A dosage device includes an outer body and an inner body displaceable relative one another and each formed with formations that engage one another to increase resistance to the displacement and to produce an audible sound corresponding to a predetermined dose of liquid traversing a passage which is formed in the outer body.Type: GrantFiled: September 21, 1999Date of Patent: June 17, 2003Assignees: GIK Invent & Design, Inc.Inventor: Gennady I. Kleyman
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Patent number: 6569126Abstract: By a cylinder ampoule (1), comprising a tubular vessel with a membrane (4) sealingly closing one end and a piston (9) closing the other end, liquid stored between said piston (9) and said membrane (4) can be pressed out through an injection needle (7) piercing the membrane (4) when the piston (9) is pressed into the ampoule (1). The tube is made from a plastically deformable material. A pressure foot (10) on which a piston rod (13) is acting abuts the piston (9), carries a spring plate (11) made from a harder material than is the ampoule (1), is mainly perpendicular to the ampoule (1) axis, and has at least one diameter which is larger than the inner diameter of the ampoule (1) so that edges of the plate (11) abutting the inner wall of the ampoule (1) are deflected away from the piston (9) to form an acute angle with said wall.Type: GrantFiled: July 8, 1998Date of Patent: May 27, 2003Assignee: Novo Nordisk A/SInventors: Jens Ulrik Poulsen, Jens Møller-Jensen
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Patent number: 6565531Abstract: A drug solution delivery device comprises barrel (1) provided with a port at a distal end thereof and opened at a proximal end thereof, gasket (2) fluid-tightly and slidably arranged in the barrel, cylindrical connecting member (3) having proximal end (32) and distal end (31) to which gasket (2) is releasably connected, plunger (4) removably connected to proximal end (32) of connecting member (3), and pressed helical spring (5) arranged between gasket (2) and connecting member (3).Type: GrantFiled: September 20, 2000Date of Patent: May 20, 2003Assignee: Nipro CorporationInventors: Takeshi Mori, Katsuhiro Hiejima, Kazuhiko Nishiyama
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Patent number: 6547763Abstract: A dose display for a medicine administration device in which rotation of a dose setting actuator (22) is transmitted to a display means comprises a flexible disc (23) carrying numbers in a band along its perimeter, which numbers are in accordance with the set dose presented in a window in a wall of the device to show said dose. During its rotation the disc (23) is deflected to follow an inner contour of the device to attain a cylindrical shape having a generatrix extending in the axial direction of the injection device and perpendicular to the axis of rotation of the disc.Type: GrantFiled: May 11, 2001Date of Patent: April 15, 2003Assignee: Novo Nordisk A/SInventors: Søren Steenfeldt-Jensen, Peter Møller-Jensen
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Patent number: 6544234Abstract: An injection device has a housing (50, 60) and therein a spring for storing energy for an injection operation. The spring (94) impinges, in the proximal direction, upon an ejection member (92) for ejecting injection liquid (16) from a vessel, displaceably arranged in the housing, at whose proximal end an injection needle is attached. Located in the housing is a displacement member (36), displaceable in the longitudinal direction, for displacing the vessel (14) in the proximal direction, in order to effect a movement of the injection needle (18) in the proximal direction and, thus, its insertion. Provided on the ejection member (92) is a detent lug (100), associated with which is a corresponding detent opening (102) in the displacement member (36). A control member (70), effective in travel-dependent fashion, serves to disengage the detent lug (100) from the detent opening (102) when the displacement member (36), during the injection operation, has traveled a predefined distance in the proximal direction.Type: GrantFiled: June 29, 2000Date of Patent: April 8, 2003Assignee: B D Medico S.A.R.L.Inventor: Jochen Gabriel
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Patent number: 6524280Abstract: Described is a dose setting limiter for medical injectors of the type having a housing accommodating an ampoule-containing medicine sufficient for a number of dosed injections, a rotary dose setting knob, which is rotational relative to the housing and by which doses may be set by rotating the dose setting knob and an injection button which, when activated, administers the set dose. The dose setting limiter includes a stationary first part connected to the housing, and a second part fitted over the rotary dose setting knob, the second part being able to rotate together with the dose setting knob when setting up a dose and the second part being rotational relative to the first part. A third part is placed between the first part and the second part, the third part having means cooperating with means on the second part for limiting the dose setting.Type: GrantFiled: January 24, 2001Date of Patent: February 25, 2003Assignee: Noro Nordisk A/SInventors: Steffen Hansen, Peter Christian Klitgaard
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Patent number: 6514230Abstract: Described is an electronic injection device wherein an electronic circuit is designed to work in two alternative modes: an air shot mode and a dose injection mode. When working in the air shot mode a small predetermined air shot dose is pressed out from the ampule when the injection button is actuated. When working in the injection mode, a dose set by operation of the dose setting means is injected by operation of the injection button. The electronic injection device is normally working in the air shot mode but shifts to work in the dose injection mode when it receives a signal indicating that the dose setting means has been operated. The circuit returns to its air shot mode when receiving a signal indicating that the set dose has been injected. This signal can originate either from a switch indicating that the protection cap is mounted or from a switch indicating that the injection button has been pressed.Type: GrantFiled: September 28, 2000Date of Patent: February 4, 2003Assignee: Novo Nordisk A/SInventors: Jens Munk, Denmark Denmark Aasmul, Henrik Ljunggreen, Lars Hofmann Christensen
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Patent number: RE38189Abstract: A medication delivery and monitoring system and methods whereby drugs are safely delivered to a patient, monitored in real-time during delivery and crucial events are recorded during delivery to provide real-time, on-line information and detail for an audit trail. A novel safety label cradle unit is disclosed. Safety label cradles (SLC's) are provided in a plurality of sizes to match varying sizes of syringes which are disposed on a cradle of the SLC to provide a constant needle height on the SLC unit independent of syringe volume (barrel diameter). A selected SLC is securely affixed to a syringe by an adhesively backed label wrapping. The label is preprinted to provide drug identification indicia and drug preparation information. The information is automatically read into the system from the label. A novel delivery station of the system monitors drug delivery as a plunger of the syringe is pushed to deliver a drug to a patient.Type: GrantFiled: July 28, 1999Date of Patent: July 15, 2003Assignee: DocuSys, Inc.Inventors: Richard Bradley Walker, Robert F. Evans, Robert Hanson, Michael F. Burrow