Having Means For Metering Material Flow To Or From Body Patents (Class 604/207)
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Patent number: 8048037Abstract: An injection device including a drive unit, a delivery unit, a dosing unit, a trigger for triggering an injection, a first coupling mechanism between the drive unit and the delivery unit, and a second coupling mechanism between the dosing unit and the drive unit, wherein the drive unit is tensioned by a rotation of the dosing unit and when the drive unit is tensioned the first coupling mechanism is disengaged and the second coupling mechanism is engaged, and wherein when an injection is triggered first the first coupling mechanism is engaged and then the second coupling mechanism is disengaged. In some embodiments, the device may include a third coupling mechanism which only releases the delivery unit after the engagement and disengagement which follow a triggering.Type: GrantFiled: March 13, 2009Date of Patent: November 1, 2011Assignee: TecPharma Licensing AGInventors: Philippe Kohlbrenner, Peter Stettler, Patrick Hostettler, Juergen Wittmann, Martin Wittwer
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Publication number: 20110238009Abstract: A device for administering injections includes a housing having an upper end, a lower end including a bottom surface with an injection needle opening, and an axis extending between the upper and lower ends. The device includes an injection needle disposed within the housing for moving between a retracted position and an extended position.Type: ApplicationFiled: March 22, 2011Publication date: September 29, 2011Applicant: Ethicon, Inc.Inventors: Moti Meron, Israel Nur, Roee Atlas
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Publication number: 20110230833Abstract: A device for successively injecting material at predetermined distances between successive injections to body tissue along a desired path of skin surface includes an injector sub-assembly having a needle configured for injecting the material into body tissue, and a displacement sub-assembly configured to facilitate precise displacement of the needle or of the device along the path between successive injections.Type: ApplicationFiled: March 18, 2011Publication date: September 22, 2011Inventors: Mania Landman, Lea Brodsky, Isaac Zukier
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Patent number: 8021345Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set the delivery dose. The injector may include a housing, a cartridge containing medicinal product, the cartridge being retained within the housing, means for selecting a dose of medicinal product to be expelled, and means for expelling the selected dose of medicinal product. The housing may be a unitary housing within which the means for selecting a dose and the means for expelling the selected dose are moveably retained. Alternatively, the injector may include a housing, a piston rod, an insert located in the housing and through which the piston may rotate, a ratchet, a dose dial sleeve, a drive sleeve, a button located on the drive sleeve and rotatable with respect to the drive sleeve, and a clutch which upon depression of the button prevents rotation between the dose dial sleeve and the drive sleeve.Type: GrantFiled: October 8, 2010Date of Patent: September 20, 2011Assignee: DCA Design International Ltd.Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Publication number: 20110224642Abstract: The present invention includes syringes with valves. The valves control communication between the interior of a barrel of the syringe and the exterior of the barrel. In syringes that include two valves, the valves may be oriented opposite one another, such that one of the valves may enable fluid to flow into the interior of the barrel of the syringe while preventing fluid from flowing in the opposite direction, while the other valve may enable fluid to flow out of the interior of the barrel while preventing fluid from flowing in the opposite direction. Alternatively, a syringe may include a single valve, which is carried at or near a distal end of its plunger. Methods for using such syringes, including, but not limited to, manual pulsed aspiration methods and manual pulsed delivery methods are also disclosed.Type: ApplicationFiled: March 12, 2010Publication date: September 15, 2011Inventor: Shawn P. Fojtik
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Patent number: 8012131Abstract: An injection device for dispensing a dose of a substance, the device including a housing, a dispensing element which can be displaced relative to the housing and a locking element which can be coupled with the dispensing element during or after a substance dispensing operation so that after the dispensing element has effected a dispensing operation once, it can no longer be operated to dispense another dose, and a method of locking an injection device after a substance has been dispensed once, whereby a dispensing element operated to dispense the substance is locked or blocked before, during or after dispensing a set dose so that no more substance can be dispensed.Type: GrantFiled: January 16, 2007Date of Patent: September 6, 2011Assignee: TecPharma Licensing AGInventors: Ulrich Moser, Christian Schrul, Juerg Hirschel
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Patent number: 8007476Abstract: An administering apparatus having a casing including a reservoir for a product to be administered, a piston which can be shifted in the reservoir in an advancing direction towards a reservoir outlet to administer the product, a piston rod, a dosing and drive element for performing a dosing movement for selecting a product dose and a delivery movement for delivering the product dose, and a dose setting member which is moved in the advancing direction during the delivery movement, and which engages the piston rod and the casing such that it can only be moved in the advancing direction jointly with the piston rod and is moved counter to the advancing direction relative to the piston rod during the dosing movement.Type: GrantFiled: January 29, 2004Date of Patent: August 30, 2011Assignee: TecPharma Licensing AGInventors: Roney Graf, Fritz Kirchhofer
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Patent number: 8002753Abstract: An apparatus includes a medicament container and an actuator assembly coupled to a proximal end portion of the medicament container. A distal end portion of the medicament container is configured to be coupled to a needle. A piston is movably disposed within the medicament container such that the medicament container is divided into a first internal portion and a second internal portion, the first internal portion containing a medicament. The actuator assembly has a pressurized fluid container, a regulator and a bias member. The pressurized fluid container is configured to move relative to the medicament container between a first position and a second position. The regulator is configured to fluidically couple the pressurized fluid container and the second internal portion of the medicament container when the pressurized fluid container is in the second position. The bias member is configured to bias the pressurized fluid container in the first position.Type: GrantFiled: December 22, 2008Date of Patent: August 23, 2011Assignee: Nordson CorporationInventors: John F. Krumme, Leslie A. Field
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Publication number: 20110190710Abstract: Therapeutic solution of an amount corresponding to a plurality of injections is injected with the distal end kept inserted in the pericardial cavity via an access port formed to penetrate under the xiphoid process. Provided is a therapeutic-solution injecting device (1) including an injection needle (3) for puncturing living tissue; a tube (6) having the injection needle (3) at a distal end thereof; a syringe connector (5) provided at a proximal end of the tube (6) and allowing connection and disconnection of a therapeutic-solution syringe (4) containing therapeutic solution; and a three-way valve (8) provided in the tube (6) between the syringe connector (5) and the injection needle (3) and having an open end.Type: ApplicationFiled: September 17, 2010Publication date: August 4, 2011Applicant: OLYMPUS CORPORATIONInventors: Shunichiro MIYOSHI, Yoshiro OKAZAKI, Michihiro SUGAHARA
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Patent number: 7976494Abstract: A device for administering a fluid product, the device including a first housing part provided with a receiver for the product, a second housing part detachably connectable to the first housing part, a piston rod held such that it can be displaced for the exertion of an emptying movement, an actuatable or releasable drive element for the piston rod, a coupling element including a coupling input element that couples the drive element to the piston rod in a coupling engagement, transmits a driving force of the drive element to the piston rod, and triggers the emptying movement, and a decoupling element displaceably connected to the second housing part and coupled to the first housing part such that it is displaced, by a movement of the housing parts in relation to each other when the housing parts are separated into a decoupling position wherein the piston rod is decoupled from the coupling input element.Type: GrantFiled: June 27, 2007Date of Patent: July 12, 2011Assignee: TecPharma Licensing AGInventors: Philippe Kohlbrenner, Daniel Kuenzli, Christoph Meier, Peter Stettler, Juergen Wittmann, Martin Wittwer
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Publication number: 20110152784Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.Type: ApplicationFiled: March 3, 2011Publication date: June 23, 2011Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
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Publication number: 20110130743Abstract: An injection device having a first sub-assembly comprises a housing and a chamber. The chamber is disposed within the housing and has proximal and distal ends, an inner surface and an exit aperture. The sub-assembly comprises a stopper movably disposed within the chamber. The stopper has an outer surface substantially in contact with the inner surface about its perimeter. The sub-assembly comprises a port adapted to receive a container containing a fluid. The stopper is fixed with respect to the housing and movement of the port causes movement of the exit aperture in relation to the stopper.Type: ApplicationFiled: June 10, 2009Publication date: June 2, 2011Inventors: Douglas Ivan Jennings, Rosemary Louise Burnell
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Patent number: 7951113Abstract: A device for administering a fluid product including a housing, a conveying device for the product, a coupling element provided for the drive of the conveying device and which can be rotated about a rotational axis, a first blocking element connected in a rotationally secure manner to the coupling element, a second blocking element detachably engageable with the first blocking element thereby preventing a rotational movement thereof in the drive direction and enabling said rotational movement to take place in the counter dosing direction, a torsion spring connected to the coupling element such that it is stressed by the rotational movement when the blocking elements are engaged in a blocked position and drives the coupling element in a rotary manner after the blocking position is released, and a release element coupled to at least one of the blocking elements such that a release movement of the release element displaces at least one of the blocking elements from the blocked position, the release element alsoType: GrantFiled: June 27, 2007Date of Patent: May 31, 2011Assignee: TecPharma Licensing AGInventors: Philippe Kohlbrenner, Daniel Kuenzli, Christoph Meier, Peter Stettler, Juergen Wittmann, Martin Wittwer, Edgar Hommann
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Publication number: 20110118700Abstract: An administration device for the administration of a liquid drug in adjustable doses may comprise an injection unit and an electronic indication unit. The injection unit may comprise a dosing mechanism and a manually operated dose setting component. The manually operated dose setting component may adjust the dosing mechanism to administer an administration dose amount of the liquid drug. The electronic indication unit may indicate a relationship between the administration dose amount and a target dose amount. A method for setting a dose of a liquid drug for administration may comprise providing an administration device, operating a manually operated dose setting component of the administration device, and continuing to operate the dose setting component until an electronic indication unit indicates that the administration dose amount is equal to the target dose amount.Type: ApplicationFiled: May 12, 2010Publication date: May 19, 2011Applicant: ROCHE DIAGNOSTICS INTERNATIONAL AGInventor: Axel Remde
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Patent number: 7935088Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.Type: GrantFiled: September 14, 2006Date of Patent: May 3, 2011Assignee: Sanofi-Aventis Deutschland GmbHInventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
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Publication number: 20110098657Abstract: An injection device comprises a first sub-assembly. The first sub-assembly comprises a chamber for holding a fluid. The chamber comprises an inner surface and an exit aperture. The first sub-assembly comprises a stopper movably disposed within the chamber and having an outer surface substantially in contact with the inner surface about its perimeter. The first sub-assembly comprises an adapter adapted to transfer fluid into the chamber.Type: ApplicationFiled: June 10, 2009Publication date: April 28, 2011Inventor: Douglas Ivan Jennings
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Publication number: 20110098658Abstract: An injection device (1) for injecting predetermined doses of liquid drug is disclosed. The injection device (1) comprises a dose setting mechanism and an injection mechanism. A torsion spring (12) is connected to the dose setting mechanism and to the injection mechanism in such a manner that energy is stored in the torsion spring (12) during dose setting, and the energy is released during injection, the stored energy being used for causing the set dose to be injected. A first mode defining element (8) and a second mode defining element (9) are angularly movable relative to each other in response to operation of the dose setting mechanism. They are also axially movable relative to each other between a first position in which the dose setting mechanism can be operated to set a dose and a second position in which the injection mechanism can be operated to inject a set dose.Type: ApplicationFiled: February 6, 2009Publication date: April 28, 2011Applicant: Novo Nordisk A/SInventors: Christian Peter Enggaard, Tom Hede Markussen, Freddy Michelsen, Morten Sørensen
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Publication number: 20110087173Abstract: The present invention provides automatic syringes that can be held with one hand in a pencil-grip in which the fingers (thumb or index finger) operate a forwardly based valve that along with selection of needle diameter and length, control the ingress or egress of fluid from the automatic syringe. These finger-controlled one-handed automatic syringes can be used in image-directed procedures such as ultrasound (sonography)-directed procedures in which the ultrasound probe is controlled with one hand and the automatic syringe with the other, although many other applications are readily apparent to those skilled in the art including biopsy, epidural injections, administration of anesthesia, and detection of blood vessels and body cavities as well as other applications.Type: ApplicationFiled: October 7, 2010Publication date: April 14, 2011Inventors: Wilmer L Sibbitt, JR., Randy R. Sibbitt
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Patent number: 7918832Abstract: A drive mechanism for use in a drug delivery device comprising an epicyclic gearbox. This drive mechanism includes a housing having a helical thread; a piston rod having a non-circular cross section and an external helical thread; a dose dial sleeve, which is threadedly engaged with the housing and being rotatable with respect to the housing; and a drive sleeve, located between the housing and the piston rod, which is threadedly engaged with the piston rod.Type: GrantFiled: April 8, 2004Date of Patent: April 5, 2011Assignee: DCA Design International Ltd.Inventors: Robert Frederick Veasey, Christopher John Jones
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Patent number: 7909793Abstract: The invention provides a silencer and silencing method which ensures adequate silencing with no deleterious increase in back pressure (which creates a lift-off force) or decrease in device performance. Pressurized gas is supplied to a driver chamber by a bleed-hole having an effective bleed-hole area and, during use of the device for particle delivery, gas is vented to the atmosphere via a silencer having an effective venting area. The bleed-hole area and venting area are chosen to ensure that the mass flow rate of gas through the effective venting area is substantially equal to or greater than the mass flow rate of gas through the effective bleed-hole area. This ensures that there is no build up of gas in the silencer device which tends to increase back pressure and hence lift-off force. Preferred embodiments of the device comprise a silencer having a large volume and a small particle exit opening. Further, there is disclosed an embodiment using one or more transfer ducts to assist particle mixing.Type: GrantFiled: July 25, 2002Date of Patent: March 22, 2011Assignee: Powderject Research LimitedInventor: Mark Anthony Fernance Kendall
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Publication number: 20110066116Abstract: A pre-filled vial assembly adapted for dispensing and delivering a fluid includes: a body member having a distal end, a proximal end, and a sidewall extending therebetween defining an interior; and a transitionable stopper disposed within the interior of the body member. At least a portion of the body member is engageable with a source of air or fluid for advancing the transitionable stopper from an initial position to an activated position in which at least a portion of a fluid contained within the interior of the body member is advanced therefrom.Type: ApplicationFiled: August 20, 2010Publication date: March 17, 2011Applicant: BECTON DICKINSON FRANCE S.A.S.Inventors: Tracy Ray Hottovy, Eric Schiller
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Patent number: 7905867Abstract: A pen-type injector is improved so that a user may select a delivery dose of medicinal product from a multidose cartridge. The injector includes a housing. a cartridge containing medicinal product retained within a housing, a piston rod, a dose selecting member to select a dose of medicinal product to be expelled, and a drive member to expel the selected dose of medicinal product. The housing is formed unitary so that the dose selecting member and the drive member are moveably retained within the housing. The injector may include ratchet means associated with the insert to ensure the piston rod only rotates in a single direction through the insert, a button located on the drive sleeve, and clutch means which upon depression of the button prevents rotation between the dose dial sleeve and the drive sleeve.Type: GrantFiled: March 2, 2004Date of Patent: March 15, 2011Assignee: DCA Design International Ltd.Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Publication number: 20110060291Abstract: Device for injecting into an eyeball a sterile liquid selected from amongst perfluorocarbons, comprising a tubular container body (3) having a first dispensing end (5) and a second end (6), and an adapter (4) for connecting a thrust fluid feed tube (6) to the second end (6). A first stopper (17) is inserted into the container body (3) in a sealed fashion and sterile liquid (2) is fed between the first stopper (17) and the first end (5). The adapter (4) consists of first and second connecting means (21), (22) to attach the adapter (4) to a feed tube (20) and to the second end (6), as well as first and second seal means (23), (24) to guarantee the fluid seal between the adapter (4) and the feed tube (20) and the container body (3). A duct (25) for the passage of a thrust fluid extends through the adapter (4) from the feed tube (20) to the container body (3).Type: ApplicationFiled: September 8, 2010Publication date: March 10, 2011Applicant: AL.CHI.MI.A. S.R.L.Inventors: MAURO BECCARO, ENRICO BETTINI, PAOLO SIGNORI
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Patent number: 7901384Abstract: A dosage device has a hollow barrel and a plunger slidable within the barrel, and a plurality of formations provided on the barrel and plunger and cooperating with one another to produce a sound signal and a pointed impulse, which corresponds to a predetermined dosage of fluid drawn into or displaced from the barrel. At least one of the barrel and plunger formations which are made of flexible material is configured to have a plurality of spaced-apart segments shaped and dimensioned to improve the quality of the sound signal.Type: GrantFiled: December 21, 2005Date of Patent: March 8, 2011Assignee: Algen & Klemer LLCInventors: Gennady Kleyman, Alexander Merson
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Publication number: 20110054412Abstract: An injection device for dispensing a product, the injection device including a moveable element which is moved for a dispensing operation, a spring, a product container holder and a product container, wherein the spring pushes against the moveable element to move the moveable element to an initial position after the dispensing operation has ended and against the product container to seat the product container in the product container holder.Type: ApplicationFiled: August 26, 2010Publication date: March 3, 2011Inventors: Adrian Eich, Aurèle Horisberger, Patrick Hostettler, Malte Kladiwa, Stefan Meier, Peter Stettler, Jürgen Wittmann
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Patent number: 7892212Abstract: A drive device for advancing an advancing element (2; 33) relative to a housing (1; 30) over a entire advancing distance (G) comprises a tensioning device having a tensioning element (3; 39) for tensioning a spring device (4). A predetermined distance (A) between the tensioning element (39) and the advancing element (33) or between the counter element (7) and the tensioning element (3) that engages with advancing element can be set according to the advancing of the advancing element (2; 33) by a partial advancing distance that is less than the entire advancing distance (G). According to a method for discharging a fluid product from a container (16) via an outlet (17), a plunger (18) is displaced inside the container (16) by means of a drive device provided with an advancing element (2; 33) and with a spring device (4), whereby the spring device (4) is tensioned by a tensioning device according to the advancing of the advancing element (2; 33) by a partial advancing distance.Type: GrantFiled: June 9, 2004Date of Patent: February 22, 2011Assignee: Roche Diagnostics International AGInventors: Hanspeter Heiniger, Stefan Jost, Roger Siegenthaler, Heinz Wuthrich
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Publication number: 20110028911Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set the delivery dose. The injector may include a housing, a cartridge containing medicinal product, the cartridge being retained within the housing, means for selecting a dose of medicinal product to be expelled, and means for expelling the selected dose of medicinal product. The housing may be a unitary housing within which the means for selecting a dose and the means for expelling the selected dose are moveably retained. Alternatively, the injector may include a housing, a piston rod, an insert located in the housing and through which the piston may rotate, ratchet means, a dose dial sleeve, a drive sleeve, a button located on the drive sleeve and rotatable with respect to the drive sleeve, and clutch means which upon depression of the button prevents rotation between the dose dial sleeve and the drive sleeve.Type: ApplicationFiled: October 8, 2010Publication date: February 3, 2011Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Publication number: 20110015580Abstract: Connector assemblies are provided for controlling flow in a fluid line that include an outer shell, an inner housing, and a tubular member. The inner housing is disposed within the outer shell and includes a boss disposed adjacent a first end of the outer shell. The inner housing is movable axially within the outer shell between first and second positions when a device is connected to the first end. The tubular member is carried by the inner housing and includes a fluid passage extending between a second end of the outer shell. The tubular member moves axially as the inner housing moves between the first and second positions, and cam features on the outer shell and the tubular member cause the tubular member to rotate as the inner housing moves between first and second positions, thereby opening a fluid path between the fluid passage and the first end.Type: ApplicationFiled: March 4, 2009Publication date: January 20, 2011Applicant: INFUSION INNOVATIONS, INC.Inventor: David K. Stroup
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Patent number: 7867202Abstract: A threaded rod for an injection device, wherein the rod includes a thread on an external surface, the thread supporting or carrying, at least partially, engaging elements and/or teeth. In one embodiment, the present invention encompasses a dosing mechanism for an injection device, including a rotational defining element which enables a threaded rod to be rotated in one direction, rotation being blocked or prevented in the counter direction by at least one blocking element which co-operates with a thread of the threaded rod, wherein the thread carries, supports or has associated teeth and/or engaging elements. In one embodiment, the present invention encompasses an injection device including at least one engaging element which co-operates with a blocking element associated with a threaded rod, whereby the threaded rod is rotatable in one direction in relation to the injection device, rotation in the opposite direction being prevented.Type: GrantFiled: November 20, 2007Date of Patent: January 11, 2011Assignee: TecPharma Licensing AGInventors: Ulrich Moser, Stefan Burren, Christian Schrul
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Publication number: 20110004191Abstract: A maximum settable dose feature is disclosed that is set by a user or health care professional one time that prevents future injections from exceeding the desired maximum dose. The feature includes a locking band initially in an unlocked configuration, which transforms to a locked configuration when activated after setting a desired maximum dose. The feature can include a trigger mechanism to transform the locking band to the locked configuration.Type: ApplicationFiled: May 27, 2010Publication date: January 6, 2011Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: Christopher John JONES
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Publication number: 20110004166Abstract: A dosage indicator for a device for the metered administration of a dose of a substance, comprising a rotatably movable metering element for adjusting the dose to be administered, an indicator element for indicating the adjusted dose, and a coupling device having a carrying element moveable rotatably about a first axis of rotation and at least one rotatable engagement element disposed on the carrying element for the mechanical coupling of the indicator element and the metering element, wherein the at least one engagement element can be rotated about a second axis of rotation on the carrying element said second axis of rotation extending transversely to the first axis of rotation.Type: ApplicationFiled: June 4, 2010Publication date: January 6, 2011Inventors: Juergen Wittmann, Aurele Horisberger, Patrick Hostettler, Malte Kladiwa, Stefan Meier, Peter Stettler, Martin Wittwer
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Publication number: 20100331787Abstract: An adaptor for discriminating connection of an oral tip having a length greater than 0.50 (12.70 mm) to a feeding line and for preventing sealed connection with a standard semi-rigid luer tip having a length less than or equal to 0.50 in (12.70 mm) is disclosed. The adaptor includes a duckbill valve spaced at least 0.50 in (12.70 mm) downstream from a first open end of the body such that when an oral tip is fully inserted into a connection port, the oral tip engages valve flaps of the duckbill valve and opens the valve, and when a standard semi-rigid luer tip is fully inserted into the connection port, the standard semi-rigid luer tip does not contact the valve flaps and the valve flaps remain in a closed position.Type: ApplicationFiled: June 30, 2009Publication date: December 30, 2010Applicant: TYCO HEALTHCARE GROUP LPInventor: Glenn Fournie
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Publication number: 20100331790Abstract: A spindle for driving a bung of a cartridge. The spindle includes a generally circular shaft having an outer surface. The generally circular shaft extends from a distal end to a proximal end of said circular shaft. A first helical groove is provided along a first portion of the outer surface. The first helical groove having a first pitch. A second helical groove provided along a second portion of the outer surface of the generally circular shaft. The second helical groove overlapping the first helical groove. The second helical groove having a second pitch.Type: ApplicationFiled: May 27, 2010Publication date: December 30, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: David Aubrey PLUMPTRE
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Publication number: 20100331791Abstract: A method and system for a dose setting mechanism of a drug delivery device. The dose setting mechanism includes an inner housing having a helical groove along an external surface of the housing. The inner housing includes a rotational stop feature near one end of the helical groove. The dose setting mechanism also includes a dial sleeve rotatably engaged with the helical groove of the inner housing. When a user rotates the dial sleeve to select a dose, the rotational stop member prevents the user from selecting a dose greater than a pre-defined maximum selectable dose.Type: ApplicationFiled: May 27, 2010Publication date: December 30, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: David Aubrey PLUMPTRE
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Publication number: 20100331806Abstract: A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove. The inner housing guides a driver having either a blocking or locking member disposed inside the driver that can lock a flexible tab to an internal groove during dose delivery in the inner housing such that the driver follows the path of the groove and to advance a spindle to move a cartridge bung. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing.Type: ApplicationFiled: May 27, 2010Publication date: December 30, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: David Aubrey PLUMPTRE, Christopher John JONES
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Publication number: 20100331789Abstract: A method and system for priming a drug delivery device. The drug delivery device includes a forced priming feature that requires the user to move the dose dial sleeve axially to cause the spindle to pre-load a cartridge bung before a first dose can be dialed.Type: ApplicationFiled: May 27, 2010Publication date: December 30, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: Christopher John JONES
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Publication number: 20100331792Abstract: A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove and a helical spline. The inner housing helical spline guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.Type: ApplicationFiled: May 27, 2010Publication date: December 30, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: David Aubrey PLUMPTRE
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Publication number: 20100331788Abstract: A resetting mechanism for a reusable drug delivery device. The device comprises a spindle and a spindle guide engaging the spindle. During a resetting step of the resetting mechanism, the spindle rotates while the spindle guide does not rotate.Type: ApplicationFiled: May 27, 2010Publication date: December 30, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: David Aubrey PLUMPTRE, Christopher John JONES
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Publication number: 20100331808Abstract: A dispenser is provided for the delivery of controlled, metered amounts of any of numerous different substances to humans or animals, such as medicaments, pharmaceuticals, cosmetics, and food products, or to deliver materials that may react upon exposure to air, such as glue. Means are provided in the dispenser to effect controlled delivery of a pre-determined amount of the substance contained in the dispenser. A one-way valve is provided to hermetically seal the portion of the dispenser containing the substance to be dispensed.Type: ApplicationFiled: September 2, 2010Publication date: December 30, 2010Inventors: Daniel Py, Norbert M. Assion, Julian V. Chan
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Publication number: 20100324497Abstract: A method and system for biasing a cartridge in a drug delivery device. An element for biasing a cartridge in a cartridge housing of a drug delivery device is provided. This non-plastic element does not comprise a coil spring. A self retained element for providing a spring bias to a cartridge in a cartridge holder of a drug delivery device comprises a first member having a shape that allows passage of a spindle of the drug delivery device. A portion of the first member is self retained by an internal surface of the drug delivery device. The self retained element biases the cartridge against an inner surface of the cartridge holder. This cartridge could be a removable cartridge.Type: ApplicationFiled: May 27, 2010Publication date: December 23, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: David Aubrey PLUMPTRE
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Publication number: 20100324528Abstract: A method and system for priming a drug delivery device. The drug delivery device includes a dose dial sleeve and an internal housing portion. The dose dial sleeve is coupled to the internal housing. The dose dial sleeve rotates on a substantially circumferential rotational path during priming of the drug delivery device. Further, the dose dial sleeve rotates on a helical path during dose setting of the drug delivery device.Type: ApplicationFiled: May 27, 2010Publication date: December 23, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: David Aubrey PLUMPTRE, Christopher John JONES, Robert Frederick VEASEY
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Publication number: 20100324493Abstract: A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove. The inner housing guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.Type: ApplicationFiled: May 27, 2010Publication date: December 23, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: David PLUMPTRE
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Publication number: 20100324495Abstract: A resettable dosing mechanism comprises a dose button and a dial grip operatively coupled to the dose button. A spindle acts on a bung of a cartridge and a driver is operatively coupled between the dose button and the spindle. During an injection of the dose, the dose button moves in an axial direction to cause the spindle to administer the dose. During resetting of the dose setting mechanism, the spindle is retracted back into the dose setting mechanism.Type: ApplicationFiled: May 27, 2010Publication date: December 23, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: Christopher John JONES
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Publication number: 20100324494Abstract: A method and system for limiting a maximum dose that may be set in a drug delivery device. A dose setting mechanism, which is operable to be coupled to a medication cartridge, comprises a lock-out mechanism that prevents one from setting a dose greater than the medication in the cartridge. The lock-out mechanism comprises a rotatable shaft. A helical groove having a first pitch is provided along a first portion of the rotatable shaft and a second pitch provided along a second portion of the rotatable shaft. The first pitch is different from the second pitch. A third pitch may be provided on a third portion of the shaft. This third pitch is provided at the end of the second pitch and is preferably different than the second pitch. The lock-out mechanism further comprises a non-rotating member disposed on the helical groove of said shaft.Type: ApplicationFiled: May 27, 2010Publication date: December 23, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: David Plumptre
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Publication number: 20100324496Abstract: A method and system for providing a drug delivery device. The drug delivery device comprises a dose setting mechanism comprising a spindle and a cartridge holder coupled to the dose setting mechanism. The cartridge holder comprising a cartridge having a movable bung at one end of the cartridge. The cartridge holder must be rotated before a dose may set with the dose setting mechanism.Type: ApplicationFiled: May 27, 2010Publication date: December 23, 2010Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: David Aubrey PLUMPTRE, James Alexander DAVIES, Christopher John JONES, Robert Frederick VEASEY
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Publication number: 20100318060Abstract: An injection device comprising a housing and a dose setting mechanism including a dose setting element. Contrary to prior art injection devices, the dose setting element can only be set at a few different dose settings. This is established by forming the dose setting element as a rotatable dish concealed within the housing and having a number of projections projecting outside the boundaries of the housing through a slot in the housing. A dose is set by activating a projection which in addition provides the user with a tactile guidance. Usually one projection is provided for one dose setting limiting the number of doses to be set to the number of projections.Type: ApplicationFiled: June 17, 2010Publication date: December 16, 2010Applicant: Novo Nordisk A/SInventors: THOMAS DEDENROTH MILLER, Steffen Hansen, Niels Christian Egholm Sorensen
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Patent number: 7850662Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.Type: GrantFiled: January 21, 2009Date of Patent: December 14, 2010Assignee: Sanofi-Aventis Deutschland GmbHInventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
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Publication number: 20100312196Abstract: A dosing device for an injection device, including a dosing element moveable or rotatable in a first direction to select a dose and a guiding element for guiding a component of the injection device, the dosing element being moved or rotated relative to the guiding element to select a dose, wherein the guiding element is rotated or moved along with the dosing element when the dosing element is moved or rotated against the first direction to adjust the selected dose. A method of adjusting a dose selected by a dosing device is encompassed, the method including selecting a dose by moving or rotating a dosing element relative to a guiding element which is moved or rotated along with the dosing element during the selecting and adjusting the selected dose by moving or rotating the dosing element in the opposite direction.Type: ApplicationFiled: May 11, 2010Publication date: December 9, 2010Inventors: Juerg Hirschel, Ulrich Moser, Christian Schrul, Markus Tschirren
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Publication number: 20100305512Abstract: The present invention relates to a delivery device for delivering predetermined amounts of fluid, comprising a body (10), a container (16) filled with fluid to be delivered arranged inside said body, said container comprising an opening for expelling said fluid and a wall (18) movable inside said container (16), a threaded plunger rod (46) arranged movable inside said body (10) in the longitudinal direction and in contact with said movable wall (18), a manually operated push means (14, 60) movable in the longitudinal direction capable of, upon operation, move said plunger rod (46) towards said movable wall (18), thereby expelling fluid, and means for transforming a generally linear movement of said push means (14, 60) to a rotational movement of said plunger rod (46).Type: ApplicationFiled: May 9, 2008Publication date: December 2, 2010Applicant: SHL GROUP ABInventors: Carlos Guillermo, David Desalvo, Lucio Giambattista
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Patent number: 7837653Abstract: A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, analgesics, and the like medicinal agents from the reservoir of the device. Uniquely, the dispenser includes a novel bellows-type reservoir and vial fill means for filling the bellows-type reservoir with the medicament to be dispensed. The dispenser also includes a novel stored energy source in the form of a constant force spring which controllably urges the medicinal fluid from the device reservoir. Additionally, the apparatus of the invention includes a novel adjustable flow rate control assembly that is disposed intermediate the fluid reservoir outlet and the outlet port of the device for precisely controlling the rate of fluid flow from the outlet port toward the patient.Type: GrantFiled: February 13, 2006Date of Patent: November 23, 2010Assignee: BioQuiddity, Inc.Inventors: Marshall S. Kriesel, Joshua W. Kriesel, Alan D. Langerud