Including Means For Controlling Piston Stroke Length Patents (Class 604/208)
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Publication number: 20090054850Abstract: An injection device including a pusher, a dosing element and a coupling element, the pusher being displaceable in an injection direction and having at least one holding or detent area, e.g. a toothed area, for detachably holding the pusher relative to the injection device, wherein the coupling element positions the pusher relative to the dosing element for fixing the axial position of the pusher relative to the dosing element.Type: ApplicationFiled: July 10, 2008Publication date: February 26, 2009Inventors: Ulrich Moser, Christian Schrul, Jurg Hirschel
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Publication number: 20090048561Abstract: An injection device including a housing with a reservoir for an injectable product, a plunger axially movable in a direction of propulsion in the reservoir, a dosing and propulsion mechanism provided for the plunger and arranged in an axial continuation of the reservoir, with a dosing or display member moveable in one axial direction relative to the plunger when setting a product dose and moveable in the opposite direction when the dose is dispensed, and, optionally, a force-imparting member which forces the dosing or display member in the direction of an axial end position, wherein at least one of the dosing or display member and optional force-imparting member axially overlap the reservoir, at least when the dosing or display member is in the end position.Type: ApplicationFiled: June 19, 2008Publication date: February 19, 2009Inventors: Stefan Burren, Philippe Kohlbrenner, Juergen Wittmann, Martin Wittwer
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Publication number: 20090043263Abstract: A hypodermic syringe includes a barrel with a plunger slidably extending therein. The barrel may include a barrel adapter at one end to define a luer hub socket and the outer walls of slots in the barrel. The plunger includes an outer plunger element and an inner plunger element telescoping together with a bungee resisting extension of the assembly. The inner and outer plunger elements may be locked in the extended position with the bungee in tension. A seal stop is located at the seal end of the plunger to define an annular pinch therewith to hold an annular seal in radial extension sealing against the internal sidewall of the barrel. A luer hub is fixed at the needle end of the barrel, A plunger cap may be advanced after injection to rotate the plunger. A resistance lock retains the cap and plunger indexed until actuation.Type: ApplicationFiled: July 1, 2008Publication date: February 12, 2009Inventors: James A. Woodard, JR., Eric G. Hassenpflug, Steven Huckaby, Steven R. Nelson, Eric R. Navin
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Patent number: 7476218Abstract: A syringe for dispensing a fluid comprising: a barrel for containing the fluid; a plunger having a plunger head slideably mounted and retractable within the barrel; and locking means. The locking means includes fixing means which, when engaged, permanently prevent retraction of the plunger head relative to the barrel beyond a predetermined distance, thereby limiting the travel of the plunger head.Type: GrantFiled: May 27, 2004Date of Patent: January 13, 2009Assignee: Intra-Tech Healthcare LimitedInventors: Adam Bloom, Karen Hamling
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Patent number: 7470259Abstract: A syringe is provided for limiting the dosage of medication delivered to a patient to a pre-determined amount. The syringe assembly includes an injector assembly and vial of medication. The injector assembly has an adjustable dosage control which rides in a track on the injector assembly for limiting vial movement. Once an appropriate dosage is selected using the dosage control, the vial is engaged with the injector assembly. As the vial is pressured into the injector assembly medication is forced through the needle. Once the vial reaches the dosage control, vial movement is obstructed and dosage effectively limited.Type: GrantFiled: March 24, 2006Date of Patent: December 30, 2008Inventor: John D. Hoyle, Jr.
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Publication number: 20080243087Abstract: A mechanism for preventing setting of a dose, which exceeds the amount of a medicament in a reservoir in an injection device. The device comprises a threaded piston rod, a limiter and a driver. The three elements are arranged such that during dose setting, the limiter is moved towards an end-of-contend position, wherein dose setting is limited. The invention comprises an accumulative and a non-accumulative embodiment. The invention further relates to a mechanism for prevention ejection of a dose exceeding the set dose.Type: ApplicationFiled: July 17, 2006Publication date: October 2, 2008Applicant: Novo Nordisk A/SInventors: Christian Peter Enggaard, Claus Schmidt Moller, Tom Hede Markussen
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Publication number: 20080234633Abstract: An injection device (1) with a travelling clutch which can be shifted between two different positions by the activation of an injection button. In the first position, the injection button and the driver (70) is allowed to rotate relatively to the piston rod (60), which is blocked from rotation by the clicker element (80). In the second position, the drive sleeve (70) and the injection button is axially movable while the piston rod (60) is allowed to rotate.Type: ApplicationFiled: June 30, 2006Publication date: September 25, 2008Applicant: Novo Nordisk A/SInventor: Lars Ulrik Nielsen
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Publication number: 20080234634Abstract: A syringe device for ejecting a dose of a medicament, the syringe device comprising: a dose limiting mechanism arranged to interact with a dose ejecting mechanism to prevent ejection of a dose exceeding a set dose, and a safety mechanism, which is arranged such with respect to the dose ejecting mechanism that, if the dose limiting mechanism fails, the safety mechanism prevents ejection of a dose exceeding the set dose.Type: ApplicationFiled: July 17, 2006Publication date: September 25, 2008Applicant: Novo Nordisk A/SInventors: Jacob Eiland, Christian Peter Enggaard, Claus Schmidt Moller, Tom Hede Markussen
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Patent number: 7427276Abstract: A syringe with which an accurate amount of a liquid can be discharged by a simple operation. The syringe 1 includes an outer tube 2, a gasket 3 slidable in the outer tube 2, a pusher 4 operable for moving the gasket 3, and a stopper 5 disposed to be slidable along the longitudinal direction of the pusher 4. The stopper 5 is fixed relative to the pusher 4 by the engagement of engaging portions, provided therein, with racks 47a, 47b formed on the pusher 4. When an operating portion 71 is depressed, the fixation condition is released, permitting regulation of the position of the stopper 5 on the pusher 4. When the depression on the operating portion 71 is canceled, the fixation condition is retained.Type: GrantFiled: July 20, 2007Date of Patent: September 23, 2008Assignee: Terumo Kabushiki KaishaInventors: Kouichi Tachikawa, Shingo Koyama, Hiromitsu Okabe
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Publication number: 20080221530Abstract: An injection device for injection of set dose of liquid medicine from a cartridge has a piston rod (4, 104)/nut (3, 113) assembly where a nut is screwed up along a threaded piston rod during a dose setting operation. During administration of the set dose the nut is also screwed along the piston rod, thus making the piston rod/nut assembly either longer or shorter. During dose setting the nut is screwed along the piston rod by rotating a dose setting drum (17). An injection button is coupled to the piston rod with a gear wheel transmission (9, 109). Movement of the injection button causes a corresponding movement of the piston rod until the nut engages an abutment in the housing (1).Type: ApplicationFiled: April 21, 2006Publication date: September 11, 2008Applicant: Novo Nordisk A/SInventors: Kristian Glejbol, Claus Schmidt Moller, Michael Ejstrup Hansen
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Publication number: 20080221517Abstract: A syringe configured with a limited maximum usable capacity. The syringe of the invention desirably has a retractable needle to prevent reuse. In the preferred embodiment, a dose-limiting structure includes a stop-ring member on the head of the plunger that abuts a constriction in the housing when the plunger is moved away from the needle to prevent the further rearward movement of the plunger. Preferably, the syringe of the invention is configured such that a user is tactilely signaled when the plunger has reached a position corresponding to a nominal fixed-dose. If the user attempts to force the stop-ring member beyond the constriction, the plunger seal is stripped off or removed from the plunger head and the syringe rendered inoperable. The features of the invention can also be applied to a nonretracting syringe.Type: ApplicationFiled: May 21, 2008Publication date: September 11, 2008Inventors: Thomas J. Shaw, Gary Wood, Mark Small
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Publication number: 20080208142Abstract: A dose setting mechanism for an injection device, e.g. for repetitive self-injection of e.g. insulin or growth hormone. Has a dose setting member, a driving element for causing a set dose to be injected, and a locking member being connected to the driving element. The position of the locking member is indicative of the remaining amount of liquid in a cartridge. When the amount is below a critical lower value, the locking member assumes a locking position where it prevents the dose setting member from being operated to set a dose. Ensures that a dose can only be set if the remaining amount of liquid in the cartridge is sufficient to ensure proper mixing of the contents of the liquid. At the same time ensures optimal usage of the available liquid. Particularly suitable for injection devices for long acting or mix insulin.Type: ApplicationFiled: February 24, 2006Publication date: August 28, 2008Applicant: NOVO NORDISK A/SInventor: Claus Schmidt Moller
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Patent number: 7377912Abstract: An administering apparatus for delivering a dosage of product including a casing with a reservoir for the product, a piston within the reservoir to deliver the product, a piston rod for engaging the piston, a drive device for driving the piston rod, and a dosage setting member mechanically engaging the piston rod and a stopper for the dosage setting member. The casing includes a front casing section containing a reservoir for the product and a rear casing section detachably connected to the front casing section. The front casing section is connected to or forms a first latching element, and the rear casing section is connected to or forms a second latching element. The latching elements are in latching engagement when the casing sections are connected. The casing sections may be axially fixed to one another by the latching engagement.Type: GrantFiled: January 29, 2004Date of Patent: May 27, 2008Assignee: TecPharma Licensing AGInventors: Roney Graf, Fritz Kirchhofer
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Patent number: 7357791Abstract: The invention provides a injection device for administering an injectable product, including a base section adapted to receive a container from which a product dose is dispensed through a needle by displacement of a piston in the container, and a drive unit including a driven member, a drive element and a damping arrangement, the drive unit for applying a force to advance the piston in the container to dispense a dose, wherein the damping arrangement generally counteracts the drive force and counter forces. The invention also encompasses a needle safety sleeve and a blocking structure for use with injection devices.Type: GrantFiled: October 30, 2006Date of Patent: April 15, 2008Assignee: TecPharma Licensing AGInventors: Fritz Kirchhofer, Jürg Steck, Peter Hostettler, Stephan Jost, Hanspeter Heiniger
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Patent number: 7329241Abstract: An embodiment of the present invention provides an apparatus for setting a dose of a drug in a syringe having a plunger, comprising an outer housing and an inner housing adapted for encircling the syringe, such that the inner housing is positioned within the outer housing to set the dose of the drug. In an embodiment, the apparatus further comprises a dosage indicator disposed on the inner housing and the outer housing further comprises an opening for viewing the dosage indicator.Type: GrantFiled: February 14, 2003Date of Patent: February 12, 2008Assignee: Valeant Pharmaceuticals North AmericaInventors: Michael W. Horvath, David F. Jensen, Mark R. Sponsel, Joseph P. Rossi, Gregory D. Malone
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Patent number: 7316670Abstract: An administering apparatus with a dosage display, including a casing, a reservoir for a fluid product, a driven device which acts on the product, a dosing means for selecting a product dosage to be delivered which includes a dosage scale including a number of dosage marks axially spaced from each other, and a drive device coupled to the driven device for driving the driven device, the drive device performing a delivery stroke from an initial position, in a drive direction, to a delivery stopper, the length of the delivery stroke counter to the drive direction being limited by selecting the product dosage using the dosing means, wherein the casing is transparent at least in an area overlapping the dosage scale, and wherein the drive device forms an indicator to the dosage scale in order to indicate the initial position of the drive device.Type: GrantFiled: July 17, 2003Date of Patent: January 8, 2008Assignee: TecPharma Licensing AGInventors: Roney Graf, Fritz Kirchhofer
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Publication number: 20070270760Abstract: An injection device includes a dispensing chamber, a plunger, a controller, a memory device resistant to sterilization, and a housing at least partially enclosing the dispensing chamber and the plunger. The dispensing chamber has an inner surface and an outer surface. The inner surface defines a cavity for receiving a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber, is capable of sliding in the cavity of the dispensing chamber, and is fluidly sealed to the inner surface of the dispensing chamber. The controller controls the operation of the injection device. The controller reads dosage data from the memory device and operates the injection device to deliver a dosage corresponding to the dosage data.Type: ApplicationFiled: March 20, 2007Publication date: November 22, 2007Inventors: Bruno Dacquay, Cesario Dos Santos, Casey Lind
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Patent number: 7201741Abstract: The invention relates to a device for dosing substances to be dispensed, in particular medicinal liquids, in particular for an injection, the device including a setting device for setting the amount of the substance to be dispensed, a signal receiving device for detecting setting signals of the setting device, an evaluation unit for receiving and evaluating the setting signals detected by the signal receiving device, a device for generating speech signals in accordance with the evaluation signals of the evaluation unit, and a device for outputting speech signals. The invention encompasses a method for dosing substances to be dispensed including the steps of detecting a setting signal of a setting device and outputting a speech signal in accordance with the setting signal detected.Type: GrantFiled: February 7, 2003Date of Patent: April 10, 2007Assignee: TecPharma Licensing AGInventor: Bruno Maire
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Patent number: 7169132Abstract: A medication delivery pen is provided having a lead screw with an enlarged portion at a first end thereof and an end longitudinally opposite the first end in contacting engagement with a plunger of a medication cartridge. The lead screw is selectively axially displaceable by a user when selectively administering a predetermined dosage amount of medication for injection into a patient. The medication delivery pen also includes a driver coaxially disposed about the lead screw; and, a reset ring non-rotatably disposed on the driver and axially slidable thereon and therealong. The reset ring is axially movable with respect to the driver when a dosage amount is set by a user of the medication delivery pen. The reset ring engages the enlarged portion of the lead screw upon a predetermined extent of relative axial movement between the reset ring and the lead screw.Type: GrantFiled: October 1, 2003Date of Patent: January 30, 2007Assignee: Becton, Dickinson and CompanyInventors: Antonio Bendek, Lucio Giambattista
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Patent number: 7169133Abstract: An injection device including a housing, a reservoir for a product to be injected, an advancing apparatus that carries out an advancing movement to discharge a selected dose of product from the reservoir, a dosing member that carries out a propulsion movement relative to the housing in a propulsion direction and a dosing movement counter to the propulsion direction, the dosing member operably coupled with the advancing apparatus such that the propulsion movement causes the advancing movement of the advancing apparatus, wherein the length of a distance determining the discharged dose is selected by the dosing movement, a first catch mechanism formed by the housing in a sleeve section that surrounds the dosing member, and a second catch mechanism formed by one of the dosing member or a separate, additional dosing catch body, wherein a catch engagement of the catch mechanisms is releasable through a rotation free dosing movement of the dosing member or the separate, additional dosing catch body.Type: GrantFiled: January 28, 2005Date of Patent: January 30, 2007Assignee: TecPharma Licensing AGInventors: Lorenz Broennimann, Fritz Kirchhofer
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Patent number: 7104972Abstract: An end-of-content arrangement for preventing a dose setting member of an injection device to be set to a dose larger that the medicament remaining in the injection device. The arrangement is particular suitable for injection devices operating with non-equistant dose volumes. The arrangement comprises an indentation provided on the housing or on the dose setting and injection member which indentation arrest a stop member when less than one dose unit is left in the cartridge. The stop member is coupled to the dose setting member such that the interaction between the indentation and the stop member prevents a dose larger that the remaining medication in being set.Type: GrantFiled: July 1, 2003Date of Patent: September 12, 2006Assignee: Novo Nordisk A/SInventors: Claus Schmidt Moller, Steffen Hansen, Christian Sorensen, Thomas Dedenroth Miller
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Patent number: 7094221Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve having a helical thread of a first lead, and a two-part piston rod. The two-part piston rod may include an outer part having a helical thread of a second lead and an inner part having a helical thread of a third lead. In such an embodiment, the first lead of the thread of the dose dial sleeve may be equal to the sum of the second lead of the thread of the outer part of the piston rod and the third lead of the thread of the inner part of the piston rod.Type: GrantFiled: March 2, 2004Date of Patent: August 22, 2006Assignee: DCA Design International Ltd.Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
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Patent number: 7090662Abstract: A dose dial and drive mechanism for use in a drug delivery device having a housing, a dose dial sleeve, a piston rod, a drive sleeve threadedly connected to the piston rod, a reset sleeve, which is located between the drive sleeve and the housing, and a dose display. When the dose dial sleeve travels towards the second end of the housing the reset sleeve is carried with the dose dial sleeve towards the second end of the housing resetting the dose display to a zero position and when the dose dial sleeve and/or the reset sleeve travels towards the first end of the housing, the dose dial sleeve and/or reset sleeve engage(s) with the drive sleeve thus advancing both the drive sleeve and the piston rod towards the first end of the housing.Type: GrantFiled: March 22, 2004Date of Patent: August 15, 2006Assignee: DCA Design International Ltd.Inventors: Steven Wimpenny, David Aubrey Plumptre, Robert Frederick Veasey
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Patent number: 7052484Abstract: A drive mechanism for an injection device is disclosed in which piston means 306 are selectively driven to expel medicament from within a medicament cartridge 40. A drive mechanism for controlling the movement of the piston means is described comprising a housing 302, a shuttle 300 located for movement within the housing 302 along a longitudinal axis between a first position and a second position, and drive means to move the shuttle 300 within the housing 302. A gear component 304 is located within the housing 302 for rotation about the longitudinal axis and associated with the piston means 306, movement of the shuttle 300 between each of the first and the second positions causing movement of the piston means 306.Type: GrantFiled: December 21, 2001Date of Patent: May 30, 2006Inventors: Robert Frederick Veasey, Robert Woolston, Christopher Nigel Langley, Shane Alistair Day
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Patent number: 7018364Abstract: A medication delivery pen is provided including a leadscrew having a plurality of threads; a driver coaxially disposed about at least a portion of the leadscrew; a dosing ring non-rotatably disposed on the driver, the dosing ring also being slidable along the driver; and, a dose knob coaxially disposed about the dosing ring. At least one tooth is formed on one of the dose knob and the dosing ring, and at least one groove is formed on the other of the dose knob and the dosing ring, with the groove being formed to receive the tooth. The dosing ring is selectively movable relative to the dose knob from a first position where the tooth and the groove are spaced apart to a second position where the tooth is received within the groove, the dosing ring being rotatable with the dose knob with the dosing ring being in the second position.Type: GrantFiled: April 28, 2005Date of Patent: March 28, 2006Assignee: Becton, Dickinson and CompanyInventors: Lucio Giambattista, Antonio Bendek
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Patent number: 6972006Abstract: A syringe device incorporating ridges that cause resistive changes to the movement of the syringe gasket or plunger, thereby providing user feedback as to the position and speed of plunger movement. Such user feedback may be useful in stressful situations, under poor lighting conditions or in other unfavorable circumstances. Additionally, in certain embodiments these ridges may aid in accurate dispension or allow the syringe to derive additional functionality, such as performing as a vacuum source. Ridges can be protrusions such as tabs, bubbles or continuous rings for single or repeated use or these ridges may be formed as indentations. Ridges may be formed in patterns, in various sizes and shapes or these ridges may be mixed and matched as required or desired. Ridges may also be formed from a soluble material and the resistive change may itself provide indication that the material has been substantially dissolved and dispensed.Type: GrantFiled: September 18, 2002Date of Patent: December 6, 2005Assignee: G6 Science Corp.Inventor: Gary William Ferguson
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Patent number: 6945962Abstract: A medical sequential syringe apparatus has two or more fluids of predetermined volume dispensed therefrom. The apparatus includes a tubular cartridge containing fluid is sealed at one end by a membrane with a hollow tubular spike mounted at one end of the body facing inwardly into the tubular body. A plunger mounted within the tubular body moves the cartridge toward the spike to puncture the membrane and allow the fluid to flow from the cartridge through the hollow of the spike out of the tubular body.Type: GrantFiled: June 21, 2002Date of Patent: September 20, 2005Inventors: Edward L. Koenig, Ronald C. DeSimoni, Jeffrey S. Mortimer, Martin T. Mortimer
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Patent number: 6945961Abstract: An injection device having an incremental clicking mechanism providing the user with an indication of the number of doses being set. For handling different types of medicaments having different dose volumes in the same type of injection device it is beneficial to provide an additional clicking mechanism which is easy changeable. The clicking mechanism is preferably a curved track provided between the dose setting member and a non-rotatable clicker element.Type: GrantFiled: July 1, 2003Date of Patent: September 20, 2005Assignee: Novo Nordisk A/SInventors: Thomas Dedenroth Miller, Claus Schmidt Moller, Steffen Hansen
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Patent number: 6932794Abstract: A medication delivery pen is provided including a leadscrew having a plurality of threads; a driver coaxially disposed about at least a portion of the leadscrew; a dosing ring non-rotatably disposed on the driver, the dosing ring also being slidable along the driver; and, a dose knob coaxially disposed about the dosing ring. At least one tooth is formed on one of the dose knob and the dosing ring, and at least one groove is formed on the other of the dose knob and the dosing ring, with the groove being formed to receive the tooth. The dosing ring is selectively movable relative to the dose knob from a first position where the tooth and the groove are spaced apart to a second position where the tooth is received within the groove, the dosing ring being rotatable with the dose knob with the dosing ring being in the second position.Type: GrantFiled: April 3, 2003Date of Patent: August 23, 2005Assignee: Becton, Dickinson and CompanyInventors: Lucio Giambattista, Antonio Bendek
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Patent number: 6899699Abstract: The present invention relates to a dose setting and expelling device comprising a drive member and a dose setting mechanism which simultaneously sets a given dose and stores the energy necessary for a subsequently driving the drive member in order to expel a dose of medicine from an injection device. According to the invention the dose setting mechanism allows adjustment in both directions, such that a given set dose can be reduced or cancelled by reversing the input motion, typically by rotating a setting member backwardly, this in contrast to the known devices which either requires an additional release mechanism or which cannot be reversed at all.Type: GrantFiled: January 2, 2002Date of Patent: May 31, 2005Assignee: Novo Nordisk A/SInventor: Christian Enggaard
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Publication number: 20040267207Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a piston rod, and a unidirectional coupling between the housing and the piston rod. The drive mechanism may also include a dose dial sleeve and a drive sleeve, with a clutch mean located therebetween to prevent relative rotation between the dial sleeve and the drive sleeve when in a coupled state and to permit relative rotation between the dial sleeve and the drive sleeve when in a de-coupled state.Type: ApplicationFiled: March 2, 2004Publication date: December 30, 2004Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Publication number: 20040267208Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.Type: ApplicationFiled: March 2, 2004Publication date: December 30, 2004Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
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Patent number: 6824529Abstract: A drug delivery device having a base member defining a skin-contacting surface, a syringe serving as a reservoir for the drug, and means for expelling drug from the syringe. The syringe is connected to the base member such that the longitudinal axis of the syringe is substantially parallel to the skin surface. A delivery needle is in communication with the syringe. The needle has an angled bend which directs the tip of the needle substantially perpendicular to the skin-contacting surface. In use, the tip of the needle is adapted to penetrate the skin of the subject.Type: GrantFiled: April 17, 2001Date of Patent: November 30, 2004Assignee: Elan Pharma International LimitedInventors: Joseph Gross, Gilad Lavi, Izrail Tsals
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Publication number: 20040220529Abstract: Devices and methods of actuating/activating agent delivery systems are provided. The subject devices include a trocar into which an agent delivery device is loaded in preparation for implantation of the agent delivery device into a patient. The action of loading the agent delivery device into the trocar serves to actuate or activate the device for the delivery of the agent which will commence upon implantation of the device. The methods include use of the trocar to actuate/activate the agent delivery device.Type: ApplicationFiled: October 15, 2003Publication date: November 4, 2004Inventors: James E. Brown, Edward M. Gillis, Andrew I. Poutiatine, William D. Kolosi, James R. Flom, Felix Theeuwes
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Publication number: 20040199125Abstract: An injection device comprising a housing and a dose setting mechanism including a dose setting element. Contrary to prior art injection devices, the dose setting element can only be set at a few different dose settings. This is established by forming the dose setting element as a rotatable dish concealed within the housing and having a number of projections projecting outside the boundaries of the housing through a slot in the housing. A dose is set by activating a projection which in addition provides the user with a tactile guidance. Usually one projection is provided for one dose setting limiting the number of doses to be set to the number of projections.Type: ApplicationFiled: February 3, 2004Publication date: October 7, 2004Inventors: Thomas Dedenroth Miller, Steffen Hansen, Niels Christian Egholm Sorensen
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Patent number: 6793646Abstract: A pen-style injector (20) includes an automated mover (70) that completes a combination of two substances such as a reconstitution process to reconstitute a lyophilized medicament prior to making an injection. The automated mover (70) is preloaded selectively released to automatically reconstitute the medicament at a controlled rate. The illustrated embodiment includes a mechanical spring (70) that provides the necessary movement of components within the injector (20) to complete the automated reconstitution process. The injector also has safety features (100) to prevent an injection prior to completing the automated combination of the substances.Type: GrantFiled: January 18, 2002Date of Patent: September 21, 2004Assignee: Becton Dickinson and CompanyInventors: Lucio Giambattista, David DeSalvo
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Publication number: 20040127858Abstract: A medication delivery pen is provided having a lead screw with an enlarged portion at a first end thereof and an end longitudinally opposite the first end in contacting engagement with a plunger of a medication cartridge. The lead screw is selectively axially displaceable by a user when selectively administering a predetermined dosage amount of medication for injection into a patient. The medication delivery pen also includes a driver coaxially disposed about the lead screw; and, a reset ring non-rotatably disposed on the driver and axially slidable thereon and therealong. The reset ring is axially movable with respect to the driver when a dosage amount is set by a user of the medication delivery pen. The reset ring engages the enlarged portion of the lead screw upon a predetermined extent of relative axial movement between the reset ring and the lead screw.Type: ApplicationFiled: October 1, 2003Publication date: July 1, 2004Applicant: Becton, Dickinson and CompanyInventors: Antonio Bendek, Lucio Giambattista
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Patent number: 6726661Abstract: Described is an electronic injection device wherein an electronic circuit is designed to work in two alternative modes: an air shot mode and a dose injection mode. When working in the air shot mode a small predetermined air shot dose is pressed out from the ampule when the injection button is actuated. When working in the injection mode, a dose set by operation of the dose setting means is injected by operation of the injection button. The electronic injection device is normally working in the air shot mode but shifts to work in the dose injection mode when it receives a signal indicating that the dose setting means has been operated. The circuit returns to its air shot mode when receiving a signal indicating that the set dose has been injected. This signal can originate either from a switch indicating that the protection cap is mounted or from a switch indicating that the injection button has been pressed.Type: GrantFiled: December 10, 2002Date of Patent: April 27, 2004Assignee: Novo Nordisk A/SInventors: Jens Munk, Denmark Denmark Aasmul, Henrik Ljunggreen, Lars Hofmann Christensen
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Publication number: 20040068236Abstract: An end-of-content arrangement for preventing a dose setting member of an injection device to be set to a dose larger that the medicament remaining in the injection device. The arrangement is particular suitable for injection devices operating with non-equistant dose volumes. The arrangement comprises an indentation provided on the housing or on the dose setting and injection member which indentation arrest a stop member when less than one dose unit is left in the cartridge. The stop member is coupled to the dose setting member such that the interaction between the indentation and the stop member prevents a dose larger that the remaining medication in being set.Type: ApplicationFiled: July 1, 2003Publication date: April 8, 2004Inventors: Claus Schmidt Moller, Steffen Hansen, Christian Sorensen, Thomas Dedenroth Miller
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Patent number: 6701976Abstract: A jig for injecting a fixed amount of insulin includes: a main fixture (1) having upper and lower sandwiching portions for sandwiching and supporting an insulin injector from both sides, at upper and lower portions on the rear surface of the insulin injector; a screw fixing piece (4) formed by extending one side of upper sandwiching portions 2 of the main fixture 1 upward; and, outside of the piece 4 for fixing an appointed quantity of screws, an injection button upper-limit position setting piece (6) whose upper portion is bent inward and which is provided with a slit (7) opened at its lower part, and the injection-button upper-limit position setting piece (6) is made freely movable up and down by screw fixation to the screw fixing piece (4) by inserting screws (8) through the slit (7).Type: GrantFiled: January 30, 2003Date of Patent: March 9, 2004Inventor: Kenichi Toraishi
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Patent number: 6699224Abstract: The invention refers to a device for administering an injectable product in doses, comprising a casing, itself comprising: a reservoir for the product; a piston which forces product out of the reservoir when moved in a feed direction towards a reservoir outlet; a drive member; a driven member which is slaved by the drive member when the drive member is moved in the feed direction, so moving the piston in the feed direction; and a dosing member which may be rotated about the sliding axis of the drive member, to set the product dosage to be administered. The drive member and the dosing member abut each other via at least one dosage stopper each, one of which is provided on the drive member and the other on the dosing member. At least one of these dosage stoppers at least partially encircles the sliding axis of the drive member in the form of a spiral. The at least one spiral dosage stopper exhibits a continuous course with a constant pitch &agr;.Type: GrantFiled: July 11, 2001Date of Patent: March 2, 2004Assignee: Disetronic Licensing AGInventors: Fritz Kirchhofer, Thomas Gurtner
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Publication number: 20040030298Abstract: A drive mechanism for an injection device is disclosed in wich piston means 306 are selectively driven to expel medicament from within a medicament cartridge 40. A drive mechanism for controlling the movement of the piston means is described comprising a housing 302, a shuttle 300 located for movement within the housing 302 along a longitudinal axis between a first position and a second position, and drive means to move the shuttle 300 within the housing 302. A gear component 304 is located within the housing 302 for rotation about the longitudinal axis and associated with the piston means 306, movement of the shuttle 300 between each of the first and the second positions causing movement of the piston means 306.Type: ApplicationFiled: June 6, 2003Publication date: February 12, 2004Inventors: Robert Frederick Veasey, Robert Woolston, Christopher Nigel Langley
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Patent number: 6685678Abstract: A drug administration system includes a cradle attached about an intravenous injection port having a flange extending therefrom. The cradle supports first drug administration information in the nature of machine and human readable code, for example, barcode. A syringe including a needle includes a flange extending from the syringe. The syringe supports second drug administration information in machine and/or human readable form. A scanner module is constructed to slidably receive the flange of the cradle and syringe whereby the syringe needle is aligned with the intravenous injection port. The module may be provided with an electronic scanning system for identifying the first and second drug administration information, as well as determining the amount of the drug being administered from the syringe to the injection port by monitoring movement of the syringe plunger. The information and data may be stored within the module for uploading to a remote location.Type: GrantFiled: March 21, 2001Date of Patent: February 3, 2004Assignee: Docusys, Inc.Inventors: Robert F. Evans, Michael F. Burrow
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Patent number: 6663602Abstract: An injection device for injection of set does of medicine from a cartridge has a nut that is screwed up along a threaded piston rod during a dose setting operation. The nut is screwed along the piston rod by rotating a dose setting drum. An injection button is coupled to the piston rod with a gear wheel transmission. Axial movement of the injection button causes a corresponding axial movement of the piston rod until the nut engages an abutment in the housing.Type: GrantFiled: June 14, 2001Date of Patent: December 16, 2003Assignee: Novo Nordisk A/SInventor: Claus Schmidt Møller
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Patent number: 6641566Abstract: A medication injection or delivery system is provided for injecting fluids such as insulin within body tissue. The device includes a housing, a flexible shaft movably mounted within the housing, and a dose setting mechanism for controlling the movement of the shaft with respect to a fluid-containing cartridge removably positioned within or mounted to the housing. The flexible shaft, according to exemplary embodiments, includes a plunger and a flexible cable connected to the dose setting mechanism. The plunger and dose setting mechanism are connected together by the flexible shaft. The dose setting mechanism, in one aspect of the invention, includes a screw, a locking mechanism, and a nut assembly connected to the flexible shaft. The dose setting mechanism is used to set the dosage and prime the catheter. The plunger retracts into a recess to permit a new cartridge to be installed quickly.Type: GrantFiled: June 24, 2002Date of Patent: November 4, 2003Assignee: Sterling Medivations, Inc.Inventors: Joel Douglas, John Ramirez, Robert Hugo
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Patent number: 6613023Abstract: The invention concerns a device for administering an injectable product in doses, wherein the device includes a casing, comprising a reservoir for the product, a piston, which when moved in a feed direction towards an outlet of the reservoir forces product from the reservoir, a gear rack, moving the piston in the feed direction, comprising a first series of teeth and a second series of teeth, a drive member, movable relative to the casing in and counter to the feed direction, and slaving the gear rack when moved in the feed direction, and a blocking means, arranged secured against shifting relative to the casing and cooperating with one of the series of teeth such that it prevents the gear rack from being moved counter to the feed direction and allows the gear rack to be moved in the feed direction.Type: GrantFiled: July 11, 2001Date of Patent: September 2, 2003Assignee: Disetronic Licensing AGInventors: Fritz Kirchhofer, Thomas Gurtner
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Publication number: 20030158523Abstract: Injector device, and method for its operation, for containers of syringe type, comprising a barrel of axially roughly constant cross-section, a front opening and at least one movable wall inserted in the barrel for displacement of a container content, the injector comprising a) a housing or housing part arranged to receive the container at least axially stationary, b) an integral or composite piston rod arrangement operable to displace the container movable wall at least in the forward direction and c) a track system for controlling or sequencing the piston rod movements, the track system comprising at least one cooperating track and follower, the cooperating track and follower being arranged stationary with respect to the housing and the piston rod respectively, or vice versa, and in cooperation allowing at least one forward for the piston rod. The track system comprises arrangements initiation, dose setting and expulsion of container content.Type: ApplicationFiled: March 26, 2003Publication date: August 21, 2003Inventors: Birger Hjertman, Rudolf Cseke
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Patent number: 6582404Abstract: A limiting mechanism which prevents the setting of a dose, which exceeds the amount of liquid left in a cartridge of an injection device, is disclosed. The injection device is the type where a dose is set by rotating a dose setting member relative to a driver and away from a fixed stop in the injection device. The dose setting member interfaces the driver such that the dose setting member can be rotated in one direction without rotating the driver. The dose is injected by rotating back the dose setting member which during the backward rotation carries the driver with it. Rotating the driver causes the piston rod to move forward inside the cartridge and expel some of the liquid contained in the cartridge. The driver is provided with a track having a length which is related to the total amount of liquid in the cartridge and which track is engaged by a track follower coupled to the dose setting member to follow rotation of this dose setting member.Type: GrantFiled: September 6, 2000Date of Patent: June 24, 2003Assignee: NNA/SInventors: Peter Christian Klitgaard, Steffen Hansen, Bo Radmer, Claus Schmidt Møller
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Patent number: 6582405Abstract: An electrically-driven dental injector used in orally injecting such an injection liquid as an anesthetic in dental treatment. Electrically-driven dental injectors includes one having a mechanism for disengaging a pinion (82) from a rack (48) in order to retract a plunger rod (44) upon completion of injection; however, it has heretofore been necessary to manually operate the operating part from outside each time. The inventive electrically-driven dental injector is so arranged that the plunger rod can be manually pushed back directly oupon completion of injection without requiring manual operation, and, to this end, the injector comprises a latch mechanism (84) for engaging/disengaging the ring gear (70) of a planetary reduction gear (50) with/from a casing (52), and an operating rod (94) extending through a support member (20) and functionally cooperating with the latch mechanism (84).Type: GrantFiled: May 7, 2001Date of Patent: June 24, 2003Assignees: Showa Yakuhin Kako Co., Ltd., Hios Inc.Inventors: Yukio Kawagishi, Fumio Tanaka, Mutsumi Shibuya, Ikuo Kitagawa, Renji Hayashi, Yoshinori Katoh
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Patent number: 6575939Abstract: The invention concerns a single-use device for injecting a dose of a medicinal product, comprising a syringe (1) and a piston rod (7) provided with a collar (9) housed in a casing formed of two parts, a front part (11) and a rear part (10), fitted inside each other and capable of sliding in relation to each other over a short traverse between two positions, a retracted position and a forward position. This device additionally includes means (35) for supporting the collar (9) of the piston rod (7) arranged so as to permit, on the one hand, injection under the effect of a propulsion spring (50) in the forward position of the parts (10, 11) of the casing and, on the other hand, backward movement of the syringe (1) inside the casing, after injection, in the retracted position of the said parts of the casing. It also includes means (28, 29) for viewing the supporting means (35) at the end of injection.Type: GrantFiled: August 3, 2000Date of Patent: June 10, 2003Assignee: Sanofi-SynthelaboInventor: Marc Brunel