Abstract: Disclosed is an injection device comprising parts, the relative movement of which causes the active substance to be injected. For this purpose, a receptacle (103, 203), into and in which a carpule/syringe can be inserted and mounted, is retained in a housing (101, 201), the receptacle (103, 203) can be moved by means of a carriage (108, 208), and a plunger (104, 204) that applies a force to the piston/s (111A, 111B; 211) of the carpule/syringe is movably retained in the receptacle (103, 203). A traction rope (114, 214) which is deflected by means of a roll (109, 209) mounted on the carriage (108, 208) is provided for performing the pricking stroke, injection stroke, and retracting stroke. One end of the traction rope (114, 214) is connected to the receptacle (103, 204) while the other end thereof is connected to a tension spring (110, 210) that is retained on the housing (101, 201).

Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.

Abstract: Disclosed is an ambulatory therapeutic fluid delivery device (10). The device includes at least one housing (200) connectable to a cannula (250), the at least one housing retaining a reservoir (220) to hold the therapeutic fluid. The device also includes a mechanically powered pumping mechanism (150) to cause delivery of at least some of the fluid from the reservoir, and a power-transfer mechanism to transfer manually-delivered power provided by a user to mechanically actuate the pumping mechanism.

Abstract: Embodiments disclosed herein relate to syringe systems for delivering and removing materials, instrument kits that include the syringe systems provided herein, and methods of using the syringe systems and kits provided herein.

Abstract: A spray or injection device that includes a casing or a pusher that includes at least one tab radially moveable between a first radial position, in which the tab does not impede the movement of the pusher with respect to the casing, and a second radial position in which the tab opposes movement of the pusher. The pusher or the casing, respectively, includes at least one ramp-shaped projection configured to bring the tab into the second radial position and then allow it to return to the first radial position. The pusher or the casing further includes at least one stop between the pusher and casing to delineate the end of a first stroke corresponding to a first dose of medicament, and the beginning of a second stroke corresponding to a second dose of medicament.

Abstract: The present invention provides a delivery device comprising a fluid cartridge holder, housing and a piston drive mechanism that comprises a hollow piston rod and a drive-shaft. The hollow piston rod has an internal thread that mates with the external thread of the drive-shaft, forming a thread connection and being axially restrained in the proximal direction relative to the housing. The drive mechanism is in turn connected to the housing via a one way ratchet such that the piston rod is prevented from moving in the proximal direction.

Abstract: An injection device with a travelling clutch which can be shifted between two different positions by the activation of an injection button. In the first position, the injection button and the drive sleeve is allowed to rotate relatively to the piston rod, which is blocked from rotation by the clicker element. In the second position, the drive sleeve and the injection button is axially movable while the piston rod is allowed to rotate.

Abstract: A drive and dosing module for an injection device, and an injection device including the module, wherein the module includes a dosing member which can be displaced into one of several dosing positions in relation to a drive member to set a product dose, wherein one of the dosing or drive members forms several dosing stops at axially different heights and rotational stops that are associated with the dosing stops and the other member forms at least one selection element, and wherein the drive member can be moved in relation to the dosing member until it reaches a trigger position in which the at least one selection element attains one of the dosing stops and, in said trigger position, the selection element and the rotational stops combine to lock the rotation of the dosing member in both directions.

Abstract: Ampoules for dispensing flowable substances and metering systems incorporating the same are described herein. An ampoule for a flowable substance includes an ampoule body comprising an interior space for receiving the flowable substance and an inner circumferential surface having a guide region and a sealing region. A piston may be disposed in the interior space of the ampoule body such that the piston is slidably displaceable along a direction of displacement. The piston includes a one sealing element for forming a seal with the inner circumferential surface in a contact zone on the outer circumference of the sealing element. The sealing element has as first compression state when the contact zone is in the guide region and a second compression state when the contact zone is in the sealing region. A second blocking device prevents movement of the contact zone from the sealing region to the guide region.

Abstract: The present invention relates to an apparatus for providing specifically metered doses of at least two flowable dental materials in desired ratios to one another. In particular, the present invention allows for controlled metering and dispensing of two or more flowable dental substances which when subsequently mixed form a dental bonding composition, dental adhesive, dental cement, or other dental restorative or preparative materials. Specifically, one embodiment of the present invention utilizes a multi-rack system as well as a drive spring action to provide a substantial mechanical advantage to the user such that a relatively long throw of the dispensing button creates a relatively short, metered distance of movement of the multiple racks and corresponding pistons in the each lumen of a cartridge containing the component of the desired dental composition, allowing for small, metered doses of each flowable dental component to be dispensed from the apparatus in the proper proportions.

Abstract: An administering apparatus for administering a fluid product, including a casing, a reservoir for the product, a driven device which acts on the product contained in the reservoir to deliver the product, and a drive device which acts on the driven device and performs a delivery stroke in a drive direction from a delivery position up to a delivery stopper to deliver a product dosage to be administered, wherein a priming stopper is provided for the drive device and limits a priming stroke of the drive device, which serves to bleed, in the drive direction, wherein the priming stroke is axially shorter than a maximum delivery stroke, and wherein the drive device can be moved in the drive direction from a priming position up to the priming stopper and transversely to the drive direction as far as the delivery position.

Abstract: A device for administering an injectable product including a housing with a reservoir for the product, a delivery device, which can be displaced out of a release position and into an activating position and, from the activating position, executes a delivery movement via which a set product dose is discharged from the reservoir, and a dosing device that, for setting a product dose, can execute a dosing movement in dosing positions predetermined by detent engagement when the delivery device occupies the release position, wherein the delivery device, when in the activating position and when moving into the activating position, is coupled to the dosing device via a blocking engagement which prevents the dosing device in the respectively set dosing position from executing dosing movements.

Abstract: A ratchet-free and gear-free one-to-one mechanism for setting a dose in a syringe device comprising a dose setting member adapted to be rotated along a piston rod with a threaded outer surface so as to set a dose to be ejected. During dose setting the piston rod is locked such that rotational movement of the dose setting member does not result in rotational movement of the piston rod. During dose ejection the piston rod and the dose setting member are locked in relation to each other such that translational movement of the dose setting member causes relative rotational and translational movement of the piston rod.

Abstract: Injection device for dispensing a medicament, comprising: a cartridge module, a dispensing mechanism which is actuated to dispense the injectable preparation, a dose-setting mechanism for setting the dose at which the injectable preparation is dispensed when the dispensing mechanism is actuated, the dose-setting mechanism comprising: a housing part (11) in which at least part of the dispensing mechanism is received, a display sleeve (13) rotatable therein, and an insertion sleeve (15) that can be inserted into the housing part (11), wherein the insertion sleeve (15) has, on its outer face, a raised surface section (20) that is transparent at least in some areas, and the housing part (11) has a recess (25) which is open at its distal edge (24) and which receives the insertion sleeve (15) in a rotationally fixed manner from the direction of the open end of the recess (25), and insertion sleeve for an injection device, dose-setting mechanism for an injection device for dispensing a medicament, and method for

Abstract: A resettable drive mechanism for a medication delivery device is proposed, said mechanism comprising a housing (13, 17, 40) with a proximal end and a distal end, a drive member (20) rotatable with respect to the housing in a second direction for delivering a dose of a medication, a piston rod adapted to be driven in a distal direction with respect to the housing by the drive member, when the drive member rotates in the second direction, a stop member adapted to prevent rotation of the drive member in a first direction opposite to the second direction with respect to the housing, when the stop member engages the drive member, and a clutch member movable with respect to the housing between a delivery position and a reset position, wherein, when the clutch member is in the delivery position, the stop member and the drive member are engaged and the drive member is prevented from rotating in the first direction with respect to the housing, and when the clutch member is in the reset position, the drive member and t

Abstract: A medical delivery system comprising a container (202) for accommodation of a medicament and a dosing assembly (204) adapted to be fastened to the container. The medical delivery system comprises a coding mechanism for ensuring that only a predetermined container can be fastened to a predetermined dosing assembly. A container for use in the medical delivery system. A dosing assembly for use in the medical delivery system.

Abstract: A drive assembly for use in a medication delivery device is provided for, which comprises a housing having a proximal end and a distal end, a drive member moveable in the proximal direction with respect to the housing for setting a dose of the medication to be delivered and in the distal direction with respect to the housing for delivering the dose, a piston rod adapted to be driven by the drive member in the distal direction with respect to the housing during movement of the drive member in the distal direction for delivering the dose and a restriction member for restricting proximal movement of the piston rod with respect to the housing during proximal movement of the drive member by mechanical interaction of the restriction member with a stop feature of the piston rod, wherein the restriction member and the stop feature are arranged for the piston rod to be moved proximally a first distance during a first proximal movement of the drive member before the restriction member and the stop feature interact mech

Abstract: A device for the dosed administration of an injectable product, including a housing with a receptacle for the product and a drive mechanism movable via a dosing element supported displaceably in the housing, wherein the drive mechanism includes engagement elements situated together in groups, the distance between the groups corresponding to a dosing amount of the injectable product and the distance between the engagement elements corresponding to a priming amount of the injectable product, and wherein the dosing element is coupled to the drive mechanism so that the dosing element at one time interacts with a group of engagement elements to administer the dosing amount and at another time interacts with an engagement element to release the priming amount.

Abstract: A dosing mechanism for use with an injection device to adjust a dose to be discharged from the injection device, the dosing mechanism including an adjusting element which can be moved relative to the dosing mechanism and including a coupling element for being releaseably coupled to a threaded bar associated with the injection device such that the adjusting element can be moved relative to the bar in one direction while a relative movement in the opposite direction is prevented, the dosing mechanism further including a retaining element with an engaging element for preventing the bar from being rotated in at least one direction, and a releasing element for uncoupling the adjusting element and bar.

Abstract: A medical delivery system comprising a container and a coupling mechanism movable between a coupling position wherein distal movement of a drive mechanism is transferred to an actuator, and a non-coupling position wherein distal movement is not transferred to the actuator. Moreover the present invention relates to a dosing assembly for use in the medical delivery system and a container for use in the medical delivery system. Finally, the present invention relates to medical delivery system comprising a dosing assembly having means for preventing a drive stem of the dosing assembly from being moved in a distal direction.

Abstract: The present invention relates to a container (1) comprising:—a body (2) a pusher (5) movable with respect to said body (2) between an “initial position” and an “end-of-use position”—a locker (7) located on said pusher (5) and forming an abutment so as to be able to abut against said body (2) between said “initial position” and “end-of-use position”,—locking means (9, 9h, 8, 5, 4a, 11, 12, 15, 29, 29a, 30a) capable of, temporarily, lock said locker (7) on said pusher (5), in the proximal direction relative to said pusher (5), an as to define a “locker locking position” and, when said pusher (5) abuts against said body (2) via said locker (7), define a “pusher locking position”,—unlocking means (9, 9a, 10, 29, 31, 13, 16, 17, 31) designed so that their triggering causes the release of said locking means so as to allow i) said locker (7) to be displaced proximally relative to said pusher (5) and ii) said pusher (5) to be moved past said “pusher locking position” toward said “end-of-use position”, which container

Abstract: A medication dispensing apparatus having a manually operable plunger axially shiftable relative to the apparatus housing. The plunger is pullable relative to the housing in a proximal direction to cock the apparatus, and when the plunger is then manually pushed back toward the housing, a piston within a medicine container of the apparatus is shifted to force medication from a needle assembly at the distal end of the apparatus. The medication dispensing apparatus also includes a priming mechanism which is operated by rotating an externally accessible driver portion to prime the apparatus for use, which priming can be performed whether or not the apparatus is in a cocked state.

Abstract: Exemplary embodiments provide subcutaneous implantation tools and methods of implanting a subcutaneous micro-device using the same. Exemplary embodiments provide subcutaneous implantation tools including a syringe body, a dissection body, and a delivery assembly. Additional exemplary embodiments provide methods of implanting a subcutaneous micro-device, including inserting the dissection body of the tool described by the exemplary embodiments into an implantation site, where the dissection body includes a micro-device, and delivering the micro-device.

Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.

Abstract: An apparatus for administering a fluid product, including a housing, a product member for accommodating the fluid product and/or a reservoir for the fluid product, which product member can be moved relative to the housing from a start position to an inserted position along a longitudinal axis of the housing, a drive member in the housing and movable relative to the product member for emptying the fluid product from the product member and/or the reservoir, wherein the drive member has at least one holding element which holds the drive member in the start position of the product member and wherein, by the movement of the product member, the holding element is moved from the holding position to a released position in which the drive member is movable relative to the housing.

Abstract: A spray or injection device that includes a casing or a pusher that includes at least one tab configured to move radially between a first radial position in which the tab does not impede the movement of the pusher with respect to the casing, and a second radial position in which the tab opposes movement of the pusher. The tab includes an opening. The pusher or the casing, respectively, includes at least one ramp-shaped projection configured to bring the tab into the second radial position then to penetrate the opening thereby allowing the tab to return to the first radial position. The pusher or the casing, respectively, further includes at least one stop region against which the tab abuts when the tab is brought into the second radial position by the projection. The stop region occurring just before the projection being opposite the opening.

Abstract: An injection device for injecting selectable amounts of a substance includes an activating mechanism including an axially moveable operating button which can rotated in a resting position only, a tubular drive element non-rotatably connected to the operating button, an axially fixed and non-rotatable guiding element, and an axially moveable driven member held non-rotatably in the device. A rotational grid is operationally between rotatable and non-rotatable components of the injection device such that the operating button can be moved two rotational directions when in the resting position whereby a selected amount of the substance to be injected can be selectively varied. For example, a dosage inadvertently selected too large by rotating the operating button too far in one direction can, in accordance with the present invention, be reduced by rotating the operating button in the opposite direction.

Abstract: A medical delivery system comprising a container for accommodation of a medicament and a dosing assembly adapted to be fastened to the container. The medical delivery system comprises a coding mechanism (150, 152) for ensuring that only a predetermined container can be fastened to a predetermined dosing assembly. The coding mechanism comprises axially extending protrusions (154, 156, 158) arranged at the interface between container and dosing assembly and arranged in a ring configuration concentric with a proximal rim portion of the container. A container for use in the medical delivery system. A dosing assembly for use in the medical delivery system.

Abstract: A container suitable for use in said medical delivery system and a medical delivery system having a container and a dosing assembly, where the container is fastenable to the dosing assembly by a movement comprising a translatory movement followed by a rotational movement. One of the container and the dosing assembly comprises one or more blocking elements movable between a blocking position and a non-blocking position responsive to the rotational movement. Each blocking element is able to engage the other one of the container and the dosing assembly.

Abstract: A substance delivery device (autoinjector) for use with a container (such as a syringe) containing the substance includes: a body arranged to house or hold the container; a plunger which is movable with respect to at least a portion of the body, the plunger being arranged to act upon the container so as to move the container with respect to the portion of the body; wherein the plunger is also arranged to expel at least a portion of the substance from the container; and wherein the device includes elements for adjusting the amount of substance to be expelled from the container. The device can also have elements for priming the container, and can accommodate containers of different size or shape.

Abstract: A medical delivery system (100) comprising a dosing assembly (104) and a container (102), wherein the container (102) is adapted to be locked to the dosing assembly (104) through a pure translational movement and unlocked from the dosing assembly (104) through a pure rotational movement. A dosing assembly (104) and a container (152) suitable for use in the medical delivery system (150).

Abstract: The medication delivery device is designed to receive a replaceable medication container and to determine an adjusted medication dose AD before each delivery of the medication contained in the medication container if the current content of the medication container is not a multiple of a prescribed dose D and is greater than the prescribed dose D. The adjusted medication dose AD is the dose to be delivered instead of the prescribed dose D during said medication delivery. The adjusted medication dose AD is determined by selecting one of a first dose, to that is higher than the prescribed dose D, and of a second dose, that is lower than the prescribed dose D, as a function of a variable B that cumulates the values (AD?D).

Abstract: The invention provides a syringe accessory device for adjustment of a predefined partial syringe dosage comprises a recess (10) for receiving a syringe body (14). Additionally, within a single portion (12) a slot (16) is located. Within the slot (16) a syringe flange (18) or finger grip can be held. To obtain a predefined dosage of liquid within the chamber of the syringe body (14), a plunger (26) is pressed in the chamber (14) in the direction of the arrow (38) until the plunger head (44) contacts a stopping means (24) whereby the stopping means is performed by a stopping surface (24) of the single portion (12). The invention further provides a kit comprising said syringe accessory device and its use for adjusting defined liquid dosages in syringes.

Abstract: A container for receiving liquids with different concentrations of an active substance that is to be administered or dosed, wherein the container includes a hollow body and a displaceable element for expelling the liquid is located for longitudinal movement in the hollow body, and wherein the cross-sectional surface area of the hollow body is inversely proportional to the concentration of the substance, such that, with identical strokes or longitudinal movements of the displaceable element, the discharged amount of active substance remains independent of the concentration of the substance in the container.

Abstract: The filling of a syringe can be performed at a faster rate using a filling sequence which expels air from the fill tube before filling the syringe. A similar method is used when changing contrast containers during a filling sequence to ensure that all the air is expelled from the fill tube before filling resumes with the new contrast container. Additionally, by including a contrast container holder that is affixed to an injector head and holds the container near the syringe tip, the filling sequence can be accomplished without requiring the operator to hold the contrast container during the sequence.

Abstract: A metered multiple aliquot/dose syringe includes a barrel having an open end and a opposing spaced apart port adapted to receive a needle. A piston is provided and slidably disposed within the barrel through the barrel open end and a push rod is connected to the piston for sliding the pistol within the barrel. Structure interconnected to the barrel and the push rod is provided for enabling stepwise movement of the push rod and the piston within the barrel and concomitant tactile and sound indicator of push rod and piston movement. A syringe within the scope of our present invention permits injection of accurate doses due to the physical stops or dosage administered indicators (i.e. elements 58 in FIG. 1, 22 in FIG. 6, 138 in FIG. 8, and elements 68 in FIG. 10) which can act to prevent hydraulic momentum from continuing to deliver fluid after thumb pressure is lifted off the push rod (piston).

Abstract: A dosing assembly (204) and/or a container (202) comprising fastening means (206,208) for fastening the container to the dosing assembly, the fastening means of the dosing assembly and/or the container defining an asymmetrical pattern in a plane transverse to an axial direction of the dosing assembly and/or a container.

Abstract: The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device.

Abstract: A specially designed syringe, without the need for finger holds is described, for use in an injection control device. The specially designed syringe is tailored for easy loading and use with the injection control device. The injection control device provides a metered or controlled injection and/or extraction rate proportional to the rate of withdrawal/injection of the body of the injection control device. The automatic metering system incorporates a syringe activating mechanism coupled to a system which is capable of proportioning the deposition rate to the retraction/injection rate of the cannula. Accordingly, more consistent and uniform distribution of the material injected can be achieved with less cannula passes as well as requiring less dependence on the skills of the practitioner of this device.

Abstract: An injection retarder for mechanically/manually reducing the rate of delivery of a hand-held hypodermic syringe and a syringe having same are provided. The injection retarder and syringe include means for selectively slowing a rate of progress of the plunger into the barrel. For example, a thumb tip rest is provided against which the thumb may be braced, thereby providing additional mechanical advantage and much finer manual control of the rate of injection. Alternatively, a set of teeth and an opposing mating tooth or pawl are provided which increase friction and slow the progress of the plunger.

Abstract: A medical delivery system (200) having a container (202) and a dosing assembly (204), where the container is fastenable to the dosing assembly by a movement comprising a translatory movement followed by a rotational movement. One of the container and the dosing assembly comprises one or more blocking elements (207) movable between a blocking position and a non-blocking position responsive to the rotational movement. Each blocking element is able to engage the other one of the container and the dosing assembly. A container suitable for use in said medical delivery system.

Abstract: An injection control device having a metered/controlled injection rate proportional to the rate of withdrawal/injection, suitable for cosmetic as well as other applications is described. For example, after the cannula is advanced into an object, the cannula is withdrawn to create a tract or tunnel within the targeted area. As the cannula is withdrawn, filler material in the injection control device is uniformly deposited into the tract or tunnel via the automatic metering system. The automatic metering system incorporates a syringe activating mechanism coupled to a system which is capable of proportioning the deposition rate to the retraction/injection rate of the cannula. Accordingly, more consistent and uniform distribution of the material injected can be achieved with less cannula passes as well as requiring less dependence on the skills of the practitioner of this device.

Abstract: Injection device comprising a tubular elongated main body, a needle shield slidably arranged in said main body, a needle shield link slidably connected to said needle shield, a enclosure containing medicament arranged in said main body, a needle connected to said enclosure, a plunger operatively arranged to said enclosure for ejecting said medicament through said needle and arranged on its upper part with a number of outwardly extending stop members, spring means arranged to said plunger for operating said plunger, a dose activating means, a needle shield spring surrounding the needle shield link.

Abstract: An administering apparatus for administering an injectable substance in doses is provided. The apparatus includes a casing with a reservoir for the substance, a conveying mechanism which acts to deliver a selected dose of the substance from the reservoir, a dosing and activating mechanism which performs a dosing movement and a delivery movement, and which is coupled to the conveying mechanism such that the delivery movement causes the selected dose to be delivered, a dosage indicator sleeve coupled to the dosing and activating mechanism, and a blocking member in a blocking engagement with the dosing and activating mechanism.

Abstract: An injection device comprising a housing, a dose setting member being operable to set a desired dose, a piston rod adapted to cooperate with a piston to cause a set dose to be expelled, and mode locking means. The mode locking means is adapted to be in a first extreme position and in a second extreme position. When the mode locking means is in the first extreme position the piston rod is prevented from cooperating with the piston, and when the mode locking means is in the second extreme position the dose setting member is prevented from being operated to set a dose. The mode locking means is adapted to be in the first extreme position during dose setting and the second extreme position during injection of a set dose. It is ensured that the liquid drug is not inadvertently expelled during dose setting and that blood or other body fluids is not sucked into the injection device during injection. Furthermore, inadvertent changing of the set dose during injection is prevented.

Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a piston rod, and a unidirectional coupling between the housing and the piston rod. The drive mechanism may also include a dose dial sleeve and a drive sleeve, with a clutch mean located therebetween to prevent relative rotation between the dial sleeve and the drive sleeve when in a coupled state and to permit relative rotation between the dial sleeve and the drive sleeve when in a de-coupled state.

Abstract: An apparatus for operating a syringe piston is developed, which is comprised of: a syringe mounting section for fixedly holding a syringe, a thread hole formed at an upper head part of the syringe mounting section, and a piston press unit having a threaded rod, which is inserted into the thread hole so that the syringe piston press unit can move up and down along the thread hole, a locking slot for fixedly inserting and retaining the medicine filled syringe, a semi-cylindrical tube to assemble with the syringe mounting section. The syringe filled with medical cement is attached to the syringe mounting section and the syringe piston is moved downward with no reverse movement when the piston press unit is rotated, so the medical cement contained in the syringe is injected with a constant pressure, so that a predetermined amount of medical cement is precisely injected into a patient's body.

Abstract: The present invention relates to a collar for use with an inflation device, the collar having a release mechanism allowing a user to advance and/or retract a plunger in a non-threaded fashion. According to one embodiment of the present invention, the release mechanism has a first position in which the plunger is threadably engaged and a second position in which the plunger can be advanced and/or retracted in a non-threaded fashion. In one embodiment the release mechanism includes a displaceable member and an engagement mechanism. In another embodiment, the release mechanism is utilized with a sleeve which allows the collar to be decoupled from the inflation device by rotation of the collar.

Abstract: A single use retractable syringe and plunger are provided. The syringe has a barrel having a collar with one or two projections that slidably engage a plurality of interconnected slots of the plunger. The slots of the syringe include one or more gates or abutments that restrict slidable movement of the projections within the slots to thereby prevent re-use of the syringe after injection and subsequent retraction of the needle.

Abstract: A limiting mechanism which prevents the setting of a dose, which exceeds the amount of liquid left in a cartridge of an injection device, is disclosed. The injection device is the type where a dose is set by rotating a dose setting member relative to a driver and away from a fixed stop in the injection device. The dose setting member interfaces the driver such that the dose setting member can be rotated in one direction without rotating the driver. The dose is injected by rotating back the dose setting member which during the backward rotation carries the driver with it. Rotating the driver causes the piston rod to move forward inside the cartridge and expel some of the liquid contained in the cartridge. The driver is provided with a track having a length which is related to the total amount of liquid in the cartridge and which track is engaged by a track follower coupled to the dose setting member to follow rotation of this dose setting member.