Material Reservoir (e.g., Cartridge, Etc.) Removably Mounted In Syringe Patents (Class 604/232)
  • Patent number: 10350357
    Abstract: A drug injection device is disclosed. A drug injection device, according to the present invention, comprises: a plunger which is connected to an ampoule filled with an injectable solution and applies pressure to the injectable solution in the ampoule; a manual plunger handle which is connected to one side of the plunger and manually applies pressure to the plunger; and an automatic plunger pressurizing unit which is selectively connected to the plunger in a position adjacent to same and automatically applies pressure to same by means of power.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: July 16, 2019
    Inventor: Kwang Bum Park
  • Patent number: 10293338
    Abstract: A device for transferring a portion of a liquid contained in a container, the device having a hollow needle for penetrating through the plug of the container; a pressure chamber for pressurizing a fluid, the chamber having the needle passing therethrough and being provided with a septum; and an approach system for causing the hollow needle and the septum to approach each other so as to increase the pressure of the fluid as a result of the approach.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: May 21, 2019
    Assignee: BIOMERIEUX
    Inventor: Frederic Foucault
  • Patent number: 10279114
    Abstract: Methods and apparatuses are disclosed with regard to syringe-transfer of a solution or other fluid, optionally with a guidance bearing, within a standard or non-standard carpule, optionally having sealed top ends and measurement gradations, i.e., indicia. One embodiment is a non-standard carpule barrel having a top portion, a bottom portion, and a barrel portion therebetween. The top portion includes an opening for receiving a syringe plunger and at least a first portion for connecting to an upper portion of the syringe. The bottom portion includes another opening capable of holding a bottom end of the carpule, wherein the carpule may be a standard carpule or a non-standard carpule. The barrel portion is located between the top portion and bottom portion, and includes a cradle, which has a length capable of holding a standard or a non-standard carpule, which has a greater width than a standard carpule.
    Type: Grant
    Filed: May 5, 2015
    Date of Patent: May 7, 2019
    Inventor: Lon J. Latiolais
  • Patent number: 10195345
    Abstract: A cartridge assembly for use with a drug delivery device is specified. The cartridge assembly comprises a cartridge with a retention cap and a cartridge holder. According to one aspect, the cartridge and the cartridge holder may be configured to be fixed to each other in a predetermined position According to another aspect, the retention cap comprises at least one coding feature configured to affix said cartridge to said cartridge holder in the predetermined position by the mating of said coding feature with a corresponding coding feature on the cartridge holder.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: February 5, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: James Senior, James Alexander Davies
  • Patent number: 10099013
    Abstract: Provided is a manual drive unit for use with a cassette unit comprising a cassette unit housing containing there within a syringe comprising a barrel for containing a volume of a liquid drug formulation; a hollow needle at a front end of the barrel, the hollow needle defining a needle tip for dispensing of the liquid drug formulation; and a plunger that is axially movable within the barrel. The manual drive unit comprises a manual drive unit housing defining a docking cavity and a needle delivery aperture, wherein said docking cavity is arranged for docking receipt of the cassette unit at a docking position; and received by the manual drive unit housing and axially movable relative thereto, a manually operable drive transfer element for transferring axial drive to the plunger of the syringe for moving the plunger into the barrel of the syringe to eject at least part of the volume of liquid drug formulation.
    Type: Grant
    Filed: August 11, 2014
    Date of Patent: October 16, 2018
    Assignee: UCB Biopharma SPRL
    Inventors: Martin John McLoughlin, Michael James David Heald, Barry Alan Knight, Dirushan Pillay
  • Patent number: 10058691
    Abstract: The invention discloses a disposable array-type micro injection needle head which comprises a lower needle seat which is configured as a cylindrical column opening at one end and having a top cap at the other end and which is configured to be connected with an injection reservoir; an upper needle seat which is located above the top cap of the lower needle seat with a cavity formed between the upper needle seat and the top cap; a through-hole formed in the top cap which is configured for communicating the cylindrical column with the cavity, wherein a pipetting needle is mounted in the through-hole which has one end communicated with the cavity and the other end located in the cylindrical column and which is configured for extracting injection from the injection reservoir into the cavity; and at least two needle tubes mounted in the upper needle seat, each of which has one end comprising a needle tip for puncturing and for injecting the injection and the other end for mounting on the upper needle seat and for c
    Type: Grant
    Filed: August 7, 2012
    Date of Patent: August 28, 2018
    Inventors: Ruifeng Yue, Yan Wang
  • Patent number: 10034985
    Abstract: A needle housing having a distal end which is removably connectable to a source of injectable fluid and a proximal end for contacting a patient, as well as to an injection apparatus comprising the needle housing. The needle housing comprises (a) a hollow needle through which the injectable fluid is deliverable to the patient, the needle having a proximal end for insertion into body tissue of the patient, and (b) a chamber having an open proximal end, the chamber surrounding at least part of the needle and extending proximally beyond the proximal end of the needle to the open proximal end. The open proximal end of the chamber is deformable and is moveable relative to the needle from a position in which the chamber extends proximally beyond the proximal end of the needle to a position in which the proximal end of the needle extends proximally through the open proximal end of the chamber.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: July 31, 2018
    Inventor: Massoud Hosseini Ardehali
  • Patent number: 10010681
    Abstract: A medicament delivery device includes a housing with a compartment for a medicament container, an injection needle arranged to housing and connectable to the medicament container for delivering a dose of medicament, a manually operated activation mechanism, an actuation mechanism operably connected to the activation mechanism and configured to extend the injection needle, upon activation of the activation mechanism, from a first position inside the housing to a second position for penetrating a patient, a plunger rod in the housing configured to act on the medicament container for delivering a dose of medicament through the injection needle, a driver configured to acting on the plunger rod for delivering the dose, and a needle cover operably arranged in the housing between a position inside the housing and an extended position outside the housing for shielding the injection needle when the injection needle is in the second position.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: July 3, 2018
    Inventors: Eugen Koch, Cheng-Jung Yang, Laura Scholze
  • Patent number: 10004849
    Abstract: The invention inter alia relates to a dispense interface for an ejection device. The dispense interface comprises at least two inlets, at least one outlet and a part having multiple portions; wherein the multiple portions are connected by living hinges such that the multiple portions are foldable towards each other; wherein the multiple portions are configured to form a fluid channel arrangement between functional surfaces of the multiple portions facing each other when the multiple portions are folded towards each other; wherein at least two functional surfaces of the functional surfaces are inclined to each other when the multiple portions are folded towards each other; and wherein the fluid channel arrangement is configured to provide fluid communication between the at least two inlets and the at least one outlet.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: June 26, 2018
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Frederic Laugere, Cristian Popa, Ben Impey, Andrew MacLeod
  • Patent number: 9974907
    Abstract: A coding system for a drug reservoir, where the drug reservoir is intended for use with a reservoir holder of a drug delivery device. The coding system includes a collar fitted around the drug reservoir. The collar includes a coding feature that is configured to pass through a corresponding coding feature provided by the reservoir holder of the drug delivery device.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: May 22, 2018
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Richard James Vincent Avery, Joseph Butler
  • Patent number: 9943389
    Abstract: A plug of an artificial insemination tube for livestock breeding includes a leading portion and a viewing portion, each having different color layers or different hardness layers, and being formed by stacking and combining different foam layers. In an artificial insemination for livestock breeding, the plug installed at the front of a sperm delivery duct is inserted into a reproductive organ of the livestock, and secretion or fluid is attached and shown on surfaces of the plug leading portion and the viewing portion with different colors to achieve the effect of detecting the physical and physiological conditions of the livestock. In addition, the leading portion is a foam layer with relatively greater hardness, density, and smoothness, so that the plug may be entered into the female livestock body more easily, and the injection hole will not be deformed easily, so as to improve the smoothness and efficiency of the artificial insemination.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: April 17, 2018
    Inventor: Sheng-Jui Chen
  • Patent number: 9937299
    Abstract: A syringe is provided with an assembly received on the distal end for adjusting the penetration depth. In embodiments, the assembly includes a collar attached to the syringe hub which moves with respect to the needle between axial positions depending on the desired needle penetration depth. The adjustable penetration depth syringe is useful in the context of self-administered drugs such as insulin, where a longer length needle is needed to fill a syringe from a vial, but a shorter penetration depth is preferred for administering a subcutaneous injection.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: April 10, 2018
    Assignee: Becton, Dickinson and Company
    Inventors: Amit Limaye, Sudarsan Srinivasan, Todd Andreoni, Edward J. Rosen, Howard Gold
  • Patent number: 9925340
    Abstract: The invention relates to a syringe closure for a syringe having a basic body, a terminal extension that extends from the basic body, which has a free end and a base arranged on the basic body. A recess is provided on the extension at a distance from its free end. The syringe closure for closing off the syringe can be attached in such a way on its extension via its free end that the syringe closure overlaps at least one recess of the extension. The syringe closure is characterized by a locking device having at least one locking element, which assumes a release position in a first functional position after the attachment of the syringe closure on the extension, and ensures a positive engagement with at least one recess on the extension in a second functional position, the locking position, and thus lockingly holds the syringe closure on the extension.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: March 27, 2018
    Assignee: Vetter Pharma-Fertigung GmbH & Co. KG
    Inventor: Joachim Glocker
  • Patent number: 9878091
    Abstract: A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: January 30, 2018
    Assignee: MEDIMOP Medical Projects Ltd.
    Inventor: Oz Cabiri
  • Patent number: 9623187
    Abstract: A resettable dosing mechanism comprises a dose button and a dial grip operatively coupled to the dose button. A spindle acts on a bung of a cartridge and a driver is operatively coupled between the dose button and the spindle. During an injection of the dose, the dose button moves in an axial direction to cause the spindle to administer the dose. During resetting of the dose setting mechanism, the spindle is retracted back into the dose setting mechanism.
    Type: Grant
    Filed: May 27, 2010
    Date of Patent: April 18, 2017
    Inventor: Christopher John Jones
  • Patent number: 9611074
    Abstract: The invention relates to a cartridge for at least two flowable components. The invention starts from a cartridge having at least two storage containers into which pistons can be inserted for dispensing components. So that the pistons cannot slip out of the storage containers again after the insertion, peripheral beads are provided at inner walls of the storage containers. To make possible cartridges which can be manufactured inexpensively and which can nevertheless be reliably sealed, it is proposed in accordance with the invention that the first inner wall has a first connection section and the second inner wall has a second connection section in which they do not have a bead. A connection web which connects the two storage containers is in this respect arranged between the first and second connection sections.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: April 4, 2017
    Assignee: SULZER MIXPAC AG
    Inventors: Ralf Seifer, Manfred Obrist
  • Patent number: 9604015
    Abstract: The present invention relates to a single-use syringe comprising a barrel (10) having an internal surface defining a chamber for retaining a fluid, a plunger (1) formed by an elongated body including a plurality of longitudinal fins (2) and optionally a piston (3) connected to the end of the plunger close to the needle, the external surface of the piston or of the end of the plunger in the case of not including a piston being in leak-tight connection with the internal surface of the barrel, where the barrel has a general external shape of a cylinder of revolution with a constant radius circular base and a variable internal shape, forming the wall of the barrel with variable thickness, generating a chamber inside which a plunger incorporating a plurality of fins (2) slides; each of the longitudinal fins (2) of the plunger has a constant height along its entire length but different from that of at least one of the other fins, which height is suitable in each fin so that the plunger (1) can be inserted tightly w
    Type: Grant
    Filed: November 18, 2010
    Date of Patent: March 28, 2017
    Assignee: Ma. Lourdes Gramage Piña
    Inventor: Ma. Lourdes Gramage Pina
  • Patent number: 9566392
    Abstract: A needle-exchangeable and self-destruction insulin syringe comprises a barrel (1), a push rod (2), a rubber piston (3) and a needle seat (4). The barrel (1) is provided with a connection needle seat (7) matched with a needle hub (5). The connection needle seat (7) is supported and fastened at the front end of the barrel by a support seat (8). The needle hub (5) is extended downwards to form a fixing ring (9). A snap ring (10) is formed at an upper end of the connection needle seat (7). The snap ring (10) is protruded into the bore of the fixing ring (9) and locked with the fixing ring (9). A large groove (13) is provided in the wall of the bore of the connection needle seat (7). The upper end of the support seat (8) is protruded into the bore of the connection needle seat (7). First elastic detents (14) are formed at the upper end of the support seat (8) and come together towards the center.
    Type: Grant
    Filed: October 19, 2010
    Date of Patent: February 14, 2017
    Assignee: Sol-Millennium Medical HK Limited
    Inventors: Xiaohui Jiang, Zuoqian Lin
  • Patent number: 9566390
    Abstract: A medication delivery device comprises a housing (1), a cap (2) configured to be attached to the housing (1) and a locking means (16, 17) configured to lock the cap (2). In a first state the cap (2) is detachable and in a second state the locking means (16, 17) locks the cap (2) if the cap (2) is attached.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: February 14, 2017
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Malcolm Stanley Boyd, Robert Veasey, David Plumptre
  • Patent number: 9549571
    Abstract: The present invention relates to a treatment device for a smoking article, comprising a smoking article receiving portion shaped and configured to receive at least a portion of a smoking article, and a needle storage portion with a needle holder and a needle connected to the needle holder. The needle is movable between an extended position in which the needle extends at least partially into the smoking article receiving portion and a retracted position in which the needle is fully retracted into the needle storage portion with respect to the extended position, to protect an operator from the needle. The invention further relates to a cartridge for such a treatment device, wherein the cartridge comprises a treatment substance for a smoking article. The cartridge comprises a plunger receiving means which is adapted to receive a plunger to force the treatment substance out of the cartridge.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: January 24, 2017
    Assignee: Philip Morris Products S.A.
    Inventor: Frederic Magne
  • Patent number: 9498581
    Abstract: The present disclosure describes a needle guard device or system that can be used with drugs requiring reconstitution. The needle guard is preferably a passive needle guard that can be used during reconstitution without activating the safety mechanism. Following administration of the medication, the needle guard shields a user from inadvertent needle sticks by extending a protective shield over the needle.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: November 22, 2016
    Assignee: Safety Syringes, Inc.
    Inventors: James M. Verespej, Philip Dowds
  • Patent number: 9387291
    Abstract: A drug delivery device for injecting a dose of a medicament, comprising at least one housing component housing a cartridge containing the medicament. The housing component comprises at least one disaggregating means comprising a perforated structure or comprising a structurally weakened portion visibly disposed on the outer circumference of the at least one housing component. The disaggregating means further having at least one bendable and/or pivot-mounted lug adapted as a gripping means and integrally formed with the housing component for dividing the housing component into at least two separate pieces, or for at least partially dividing the housing component into at least two mutually interconnected pieces that can be pivoted with respect to each other.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: July 12, 2016
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Jugl, Axel Teucher
  • Patent number: 9345832
    Abstract: A cartridge holder for a drug delivery device. The cartridge holder comprises a proximal portion for receiving a cartridge filled with a medicinal fluid to be dispensed by the drug delivery device, and a distal portion comprising a mount for a piercing assembly. The piercing assembly is adapted to provide a fluid-transferring connection with the inner volume of the cartridge by way of a piercing element pointing in distal direction with a pointed free end section. Retaining means adapted to substantially prevent the cartridge from displacing in proximal direction with respect to the proximal portion distal portion.
    Type: Grant
    Filed: December 1, 2010
    Date of Patent: May 24, 2016
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Jugl, Axel Teucher, Kerstine Hemmann
  • Patent number: 9271896
    Abstract: An apparatus having a container comprising a volume. The volume is configured to retain a single dose of a medication appropriate for a specific classification of a weight of a patient. A first indicia is disposed on an exterior surface of the container. The first indicia indicates a type of the medication. A second indicia is disposed on the exterior surface. The second indicia indicates the specific classification, wherein the container, pre-packaged with the single dose, is appropriate for a single use dosing of the patient having the specific classification.
    Type: Grant
    Filed: June 21, 2014
    Date of Patent: March 1, 2016
    Inventor: David Clements
  • Patent number: 9205197
    Abstract: A method and system for proving a drug delivery device. The device comprises a drug delivery device housing and a medicament contained in the drug delivery device housing. A dose dial sleeve is positioned in the housing and is rotatable to set a non-inverted dose of the medicament contained in the medical delivery device. The non-inverted dose may be increased by turning the dose dial sleeve in a direction towards a user of the drug delivery device. The dose medicament may be decreased by rotating the dose dial sleeve in a direction away from the user.
    Type: Grant
    Filed: January 22, 2009
    Date of Patent: December 8, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Christoph Dette, Paul Jansen, Christian Pommereau, Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
  • Patent number: 9180254
    Abstract: Disclosed herein are fastening features for cartridge assemblies that include coding features that help dedicate a medicament reservoir to specific injection devices. An exemplary cartridge assembly comprises a cylindrical inner surface for holding medicament and a cylindrical outer surface comprising a fastening feature having a first coding element protruding from the cylindrical outer surface. The coding element is configured to engage a complementary coding feature on the fastener on a dose setting member specifically configured to dispense the medicament, thereby allowing only the correct cartridge assembly to connect to the correct dose setting member.
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: November 10, 2015
    Inventors: Richard James Vincent Avery, Paul Draper, Aled Meredydd James
  • Patent number: 9173726
    Abstract: A medical syringe with a light source mounted on a distal end of the syringe to provide illumination of an injection site, a battery pack receiver configured to receive a battery pack with magnetic attraction a proximal end of the syringe, and a control circuit that is configured to illuminate the light source when the control circuit detects movement of the syringe and disconnects the battery from the light source either after a fixed period of time or after motion of the syringe ceases. Ideally the light source is a disc-shaped array of LED lights. The syringe is constructed of materials that can be sterilized.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: November 3, 2015
    Inventor: Christopher R. Sabourin
  • Patent number: 9144515
    Abstract: The invention relates to a device for administering a liquid drop by drop. This administering device comprises a packaging filled with the liquid, an outflow channel with an administering opening, and means connected to the outflow channel for opening the packaging, wherein the opening means and the packaging are movable relative to each other. The device can have means for receiving the packaging, which receiving means can be adapted to fix the packaging, wherein the opening means are then movable relative to the receiving means. The opening means can conversely also be fixed relative to the receiving means, wherein the packaging is then movable in the receiving means. The opening means can be formed by a sharp outer end of the outflow channel.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: September 29, 2015
    Assignee: Sparkle Innovations B.V.
    Inventors: Hubertus E. Hilbrink, Johannes Van Der Heiden, Leonardus H. M. Lammers
  • Patent number: 9119921
    Abstract: A safety device to be used with a vial, or capsule, has a collar dimensioned to slidably fit about the body of the vial. Extending from the collar is a neck member that has connected to its other end a housing pivotable to a position along the longitudinal axis of the vial. A latch member having a lip is integrated to the neck member and extends out from the neck member in a direction towards the center of the collar. Neck member is fabricated to have an elastic characteristic so that if it is not biased by any external force, it will return to its original position. As the collar of the safety device is moved along the body of the vial, neck member is biased away from the vial as the latch member maintains contact along the outer surface of the vial, and then the outer surface of the hub formed at the top end of the vial.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: September 1, 2015
    Inventor: David R. MacLean
  • Patent number: 9107994
    Abstract: A fluid infusion device is provided. The fluid infusion device can include a fluid reservoir having a barrel portion and a housing defining a receiving portion for removably receiving the fluid reservoir within the housing. The housing can have a first side including a first engagement system that cooperates with the barrel portion to bias the fluid reservoir relative to the housing in a direction substantially opposite a direction of fluid flow out of the fluid reservoir.
    Type: Grant
    Filed: January 18, 2013
    Date of Patent: August 18, 2015
    Assignee: Medtronic MiniMed, Inc.
    Inventor: Matthew William Yavorsky
  • Patent number: 9028455
    Abstract: A cylindrical holder for housing a pharmaceutical product container in a hand-piece of a surgical instrument for perforating dense tissue of a human or animal body and injecting a pharmaceutical product behind or in the tissue. The cylindrical holder connects an injection needle with the container. The holder has a tubular wall for receiving the container. The tubular wall includes contact areas defined by bridges of material subsisting between cut-outs located along circumferential rows, the bridges of material having deflections towards the inside of the cylindrical holder. A surgical instrument for perforating dense tissue of a human or animal body and injecting a pharmaceutical product behind or in the tissue, and includes a hand-piece and the cylindrical holder.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: May 12, 2015
    Assignee: Dentalhitec
    Inventors: Olivier Villette, Denis Ripaud
  • Publication number: 20150119811
    Abstract: An adaptor top for a medicament cartridge, the medicament cartridge including a cylinder having a main body portion, a neck portion at a first end having a radially outwardly directed flange portion, a narrowing shoulder portion connecting the body portion and the neck portion, a cap beaded across the first end thereby to retain a fluid impermeable membrane, and the adaptor top comprising a first cylindrical body portion having a radially inwardly directed flange at one end, in use to be seated over and against the cap and a second cylindrical skirt portion being adapted, in use, to be seated against the shoulder portion of the cartridge, the second skirt portion including a plurality of fingers, the free ends of the fingers in use being adapted to be seated beneath the outwardly directed flange of the medicament cartridge.
    Type: Application
    Filed: December 31, 2014
    Publication date: April 30, 2015
    Inventor: Robert WOOLSTON
  • Patent number: 8998876
    Abstract: An ampoule holder for receiving an ampoule that has a closure element with a radial projection, the ampoule holder including an ampoule seat and a securing member operably coupled to the ampoule seat, wherein the radial projection of the closure element can be arranged between the ampoule seat and securing member.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: April 7, 2015
    Assignee: TecPharma Licensing AG
    Inventors: Annette Drunk, Marius Büttler, Frank Schiffmann, Sara Tretola, Kurt Weber, Ulrich Moser, Jürg Hirschel
  • Patent number: 8998857
    Abstract: The present invention relates to a cartridge holder assembly for a drug delivery device comprising of a cartridge holder adapted to receive a cartridge filled with a medicament to be dispensed by the drug delivery device, wherein the cartridge holder comprises a first through opening at a distal end section to receive a piercing element adapted to penetrate a sealing member of the cartridge, a support structure adjacently arranged to the first through opening; and a constriction member arranged between the support structure and a distal end face of the cartridge and having a second through opening smaller than the first through opening.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: April 7, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Jugl, Torsten Kraft
  • Patent number: 8992477
    Abstract: An injector including a syringe arranged along a longitudinal axis, a removable cover for removable engagement with the syringe and a cover removal assembly including an outer portion which is engagable by a user and is movable axially in a cover disengagement direction along an axial travel path with respect to the longitudinal axis and an inner portion which includes at least one engagement portion which is engagable with the removable cover, whereby axial movement of the inner portion in the cover disengagement direction removes the removable cover from the syringe, at least one of the outer portion and the inner portion being configured such as to provide an axially floating lost motion engagement between the outer portion and the inner portion.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: March 31, 2015
    Assignee: Elcam Agricultural Cooperative Association Ltd.
    Inventors: Lior Raday, Ehud Carmel, Lior Mareli, David Daily, Guy Keenan
  • Patent number: 8986259
    Abstract: Various embodiments of piston rod assemblies, drug delivery devices making use of such piston rod assemblies, and methods for assembling such piston rod assemblies and drug delivery devices are provided. In one embodiment, a piston rod assembly for a drug delivery device is provided, wherein the piston rod assembly is configured to engage a piston of a medicament cartridge. The piston rod assembly comprises (i) a piston rod, (ii) at least one adjusting member displaceably engaged with a distal end section of the piston rod, wherein the at least one adjusting member is displaceable along a long axis of the piston rod, and (iii) at least one interlock member configured to mutually lock the at least one adjusting member and the piston rod in an arbitrary relative axial position.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: March 24, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Helmer, Christoph Eissengarthen, Winfried Huthmacher, Carsten Mosebach, Leo Zeimetz
  • Patent number: 8968257
    Abstract: A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5?, 6, 6?) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27?, 28?) on the distal end of a cartridge assembly (20).
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: March 3, 2015
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Uwe Dasbach, Steffen Raab, Michael Harms, Udo Stauder, Volker Korger
  • Patent number: 8945053
    Abstract: An injection device having a distal end, and including a needle located inside the injection device in an initial position, wherein the needle is moveable to a puncturing position in which the needle projects from the distal end, an open region located distally relative to the needle in the initial position of the needle and having a dimension, and a reduction piece moveable relative to the opening region whereby the dimension may be reduced.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: February 3, 2015
    Assignee: TecPharma Licensing AG
    Inventors: Patrick Vogt, Ursina Streit
  • Patent number: 8945063
    Abstract: Injection systems comprising a powered injector and one or more hazardous agents are disclosed.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: February 3, 2015
    Assignee: Antares Pharma, Inc.
    Inventors: Paul K. Wotton, Peter L. Sadowski, John William Hayes
  • Patent number: 8945070
    Abstract: A trigger operated syringe (100) for intramammary injection of antibiotics has a fluid containing syringe cartridge (203) activated by a plunger (206) which is inserted into the syringe cartridge (203A) and expels fluid when the trigger (205) is pulled. A syringe cartridge holding mechanism (223) holds the syringe cartridge in place until the trigger (205) is released and the plunger (206) retracted. Single syringe cartridge (203) and multiple syringe cartridge (204) versions are disclosed. The plunger moves in a direction which is effectively perpendicular to the direction of movement of the trigger, allowing for ease of injection to a cow's teats, and ejection of the spent cartridges.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: February 3, 2015
    Assignee: Merial Limited
    Inventors: Robert William Lachlan Holmes, Rodney Gordon Walker, Todd Donald Ebbett, Colin Anthony Standing, Peter Robert Williams, Giovanni Ciampa, Michael Rossignuolo, Robert John Smith
  • Patent number: 8939944
    Abstract: A product dispensing apparatus including a reservoir module, a dosing module and a dose setting member. The reservoir module includes a front casing section, a block, a first connector, a piston, and a piston rod moveable in a dispensing movement and against the dispensing movement, and including a return block engageable with the block, wherein engagement between the block and the return block prevents the piston rod from moving against the dispensing movement. The dosing module includes a rear casing section, including a second connector which is engageable with the first connector to form a detachable connection between the reservoir module and the dosing module, and a dosing and drive device. The dose setting member engages the piston rod such that it is moveable together with and in the same direction as the piston rod during the dispensing movement and is moveable relative to the piston rod against the dispensing movement.
    Type: Grant
    Filed: August 9, 2007
    Date of Patent: January 27, 2015
    Assignee: TecPharma Licensing AG
    Inventors: Roney Graf, Fritz Kirchhofer
  • Patent number: 8932268
    Abstract: A medication cartridge injection assembly facilitates and tracks dispensation of medication such as epinephrine during a heart attack. The assembly includes a frame and a housing having a plurality of chambers holding cartridges of medication. A barrel is coupled to the frame and selectively alignable with each chamber. A plunger is aligned with the barrel to engage the cartridge positioned in an aligned chamber. An actuator engages the cartridge upon manipulation of the actuator. A processor is operationally coupled to a timer actuated by manipulation of the actuator. An alert mechanism is operationally coupled to the processor to provide an alert related to a time expired since a most recent dispensing of medication.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: January 13, 2015
    Inventor: Edward D. Struzinski
  • Publication number: 20150011949
    Abstract: Drug delivery device comprising a cartridge holder adapted to receive and hold a cartridge in a loaded position, the cartridge holder comprising a distal opening adapted to receive the cartridge. The drug delivery device further comprises an expelling assembly adapted to engage and axially displace a piston in a loaded cartridge to thereby expel a dose of drug from the cartridge, and snap locking means acting on a cartridge being inserted in the cartridge holder, the snap locking means having a locked state in which the cartridge is held in the loaded position and an un-locked state in which the cartridge can be removed from the cartridge holder.
    Type: Application
    Filed: January 25, 2013
    Publication date: January 8, 2015
    Inventor: Morten Soerensen
  • Patent number: 8911395
    Abstract: A syringe carpule for storing, transporting and in situ mixing of a local anesthetic, such as lidocaine, and a buffer, such as sodium bicarbonate, and delivery of buffered anesthetic solution according to the present invention that comprises a hollow tubular body received within the frame of a carpule syringe, at least one axially movable plunger within the body and configured to be engaged and moved by a rod of the carpule syringe, a seal pierced by a rear portion of a needle coupled to the carpule syringe, a first chamber within the body filled with anesthetic solution during storing and transport, a second chamber defined within the body filled with buffering solution during storing and transport; and a breachable separating member between the first and second chamber configured to be removed for in situ mixing of the buffering and the anesthetic solutions allowing for delivery of a buffered anesthetic solution.
    Type: Grant
    Filed: November 1, 2012
    Date of Patent: December 16, 2014
    Inventor: George Just
  • Publication number: 20140358093
    Abstract: Drug delivery system comprising a cartridge with an axially displaceable piston, and a front-loaded cartridge holder adapted to axially receive and hold a cartridge in a loaded position. The cartridge comprises first coupling means arranged at the distal portion, and the cartridge holder comprises second coupling means arranged at the distal portion, wherein the first and second coupling means are configured to engage each other to thereby axially secure a cartridge mounted in the cartridge holder.
    Type: Application
    Filed: January 25, 2013
    Publication date: December 4, 2014
    Inventors: Morten Soerensen, Jesper P. Windum, Kalle H. Madsen, Christian Plambech, Knud S. Winther
  • Patent number: 8888745
    Abstract: The invention pertains to an applicator (1) for inserting an implant, in particular a rod-like implant (2) containing an active substance, under the skin of a human or animal, comprising a housing (3), a cannula (6) extending from the housing (3), and a handle (15) for grasping and maneuvering the applicator (1) and the cannula (6) during insertion of an implant (2). In accordance with the invention, the handle (15) extends above at least part of the length of the cannula (6). Such a handle facilitates insertion of the cannula and/or accurate positioning of the implant.
    Type: Grant
    Filed: January 20, 2006
    Date of Patent: November 18, 2014
    Assignee: Merck Sharp & Dohme B.V.
    Inventors: Iris Epkjen Hobo Van Der Graaf, Maurice Petrus Wilhelmus Tak, Juergen Schmidt, Hendricus Johannes Vertegaal
  • Publication number: 20140336592
    Abstract: Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes an annular groove formed in a distal end and adapted to receive a circlip disposed in a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.
    Type: Application
    Filed: December 5, 2012
    Publication date: November 13, 2014
    Inventors: Yannick Hourmand, Douglas Ivan Jennings, Matthew Ekman
  • Publication number: 20140336587
    Abstract: Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The housing cavity is arranged for receipt of a syringe suitable for use in the injected delivery of drug to a patient. The syringe has a barrel for containing a volume of a liquid drug formulation, the barrel defining an end flange at the rear end thereof and a forward shoulder at the forward end thereof. The cassette unit includes a sleeve form adapter arranged for receipt by the syringe barrel and to fit at least partly over the end flange of the syringe barrel. Accommodation of different syringe sizes within the same cassette unit geometry is achievable by selecting a sleeve form adapter tailored to the particular sizing of the barrel of each different syringe.
    Type: Application
    Filed: June 4, 2012
    Publication date: November 13, 2014
    Applicant: UCB Pharma SA
    Inventors: Martin John McLoughlin, Kevin Richard Lozeau, Agnete Enga, Eric Freitag, Daniel Formosa, Michael Schumann, Brian Lipford, Jake Cowperthwaite, Alex Flamm, Ilario Melzi
  • Patent number: 8876785
    Abstract: The present invention relates to a delivery member attachment device (10) comprising a neck (12) having an inner space intended to accommodate a connection part of a medicament container, which neck (12) is intended to receive a delivery member (30) for creating a passage between the medicament container via the connection part and through the delivery member, that said neck (12) is arranged with threads (14) arranged to engage with corresponding threads (34) of an attachment part (32 of said delivery member (30), and wherein said neck (12) further is arranged with a number of slits (16) providing a number of tongues (18) between said slits, and wherein said tongues (18) are arranged to flex inwards, when a delivery member (30) is to be attached, to allow an axial pushing of said attachment part (32) onto, and in engagement with, said neck (12).
    Type: Grant
    Filed: November 26, 2009
    Date of Patent: November 4, 2014
    Assignee: SHL Group AB
    Inventor: Anders Holmqvist
  • Patent number: 8876770
    Abstract: Infusion systems for pumping fluid into a body of a user, and methods for providing infusion systems, are disclosed. The infusion systems include an infusion pump, wherein the infusion pump comprises an infusion pump housing including a cavity. A fluid storage is removably inserted into the cavity of the infusion pump housing wherein, the fluid storage comprises a cartridge and an adapter connected to the cartridge such that the adapter encases the cartridge, and an infusion set is removably connected to the fluid storage.
    Type: Grant
    Filed: March 30, 2010
    Date of Patent: November 4, 2014
    Assignee: Roche Diagnostics International AG
    Inventors: Torsten Kraft, Hanspeter Stoller, Simon Scheurer, Christian Thalmann