Abstract: A resettable dosing mechanism comprises a dose button and a dial grip operatively coupled to the dose button. A spindle acts on a bung of a cartridge and a driver is operatively coupled between the dose button and the spindle. During an injection of the dose, the dose button moves in an axial direction to cause the spindle to administer the dose. During resetting of the dose setting mechanism, the spindle is retracted back into the dose setting mechanism.

Abstract: The invention relates to a cartridge for at least two flowable components. The invention starts from a cartridge having at least two storage containers into which pistons can be inserted for dispensing components. So that the pistons cannot slip out of the storage containers again after the insertion, peripheral beads are provided at inner walls of the storage containers. To make possible cartridges which can be manufactured inexpensively and which can nevertheless be reliably sealed, it is proposed in accordance with the invention that the first inner wall has a first connection section and the second inner wall has a second connection section in which they do not have a bead. A connection web which connects the two storage containers is in this respect arranged between the first and second connection sections.

Abstract: The present invention relates to a single-use syringe comprising a barrel (10) having an internal surface defining a chamber for retaining a fluid, a plunger (1) formed by an elongated body including a plurality of longitudinal fins (2) and optionally a piston (3) connected to the end of the plunger close to the needle, the external surface of the piston or of the end of the plunger in the case of not including a piston being in leak-tight connection with the internal surface of the barrel, where the barrel has a general external shape of a cylinder of revolution with a constant radius circular base and a variable internal shape, forming the wall of the barrel with variable thickness, generating a chamber inside which a plunger incorporating a plurality of fins (2) slides; each of the longitudinal fins (2) of the plunger has a constant height along its entire length but different from that of at least one of the other fins, which height is suitable in each fin so that the plunger (1) can be inserted tightly w

Abstract: A needle-exchangeable and self-destruction insulin syringe comprises a barrel (1), a push rod (2), a rubber piston (3) and a needle seat (4). The barrel (1) is provided with a connection needle seat (7) matched with a needle hub (5). The connection needle seat (7) is supported and fastened at the front end of the barrel by a support seat (8). The needle hub (5) is extended downwards to form a fixing ring (9). A snap ring (10) is formed at an upper end of the connection needle seat (7). The snap ring (10) is protruded into the bore of the fixing ring (9) and locked with the fixing ring (9). A large groove (13) is provided in the wall of the bore of the connection needle seat (7). The upper end of the support seat (8) is protruded into the bore of the connection needle seat (7). First elastic detents (14) are formed at the upper end of the support seat (8) and come together towards the center.

Abstract: A medication delivery device comprises a housing (1), a cap (2) configured to be attached to the housing (1) and a locking means (16, 17) configured to lock the cap (2). In a first state the cap (2) is detachable and in a second state the locking means (16, 17) locks the cap (2) if the cap (2) is attached.

Abstract: The present invention relates to a treatment device for a smoking article, comprising a smoking article receiving portion shaped and configured to receive at least a portion of a smoking article, and a needle storage portion with a needle holder and a needle connected to the needle holder. The needle is movable between an extended position in which the needle extends at least partially into the smoking article receiving portion and a retracted position in which the needle is fully retracted into the needle storage portion with respect to the extended position, to protect an operator from the needle. The invention further relates to a cartridge for such a treatment device, wherein the cartridge comprises a treatment substance for a smoking article. The cartridge comprises a plunger receiving means which is adapted to receive a plunger to force the treatment substance out of the cartridge.

Abstract: The present disclosure describes a needle guard device or system that can be used with drugs requiring reconstitution. The needle guard is preferably a passive needle guard that can be used during reconstitution without activating the safety mechanism. Following administration of the medication, the needle guard shields a user from inadvertent needle sticks by extending a protective shield over the needle.

Abstract: A drug delivery device for injecting a dose of a medicament, comprising at least one housing component housing a cartridge containing the medicament. The housing component comprises at least one disaggregating means comprising a perforated structure or comprising a structurally weakened portion visibly disposed on the outer circumference of the at least one housing component. The disaggregating means further having at least one bendable and/or pivot-mounted lug adapted as a gripping means and integrally formed with the housing component for dividing the housing component into at least two separate pieces, or for at least partially dividing the housing component into at least two mutually interconnected pieces that can be pivoted with respect to each other.

Abstract: A cartridge holder for a drug delivery device. The cartridge holder comprises a proximal portion for receiving a cartridge filled with a medicinal fluid to be dispensed by the drug delivery device, and a distal portion comprising a mount for a piercing assembly. The piercing assembly is adapted to provide a fluid-transferring connection with the inner volume of the cartridge by way of a piercing element pointing in distal direction with a pointed free end section. Retaining means adapted to substantially prevent the cartridge from displacing in proximal direction with respect to the proximal portion distal portion.

Abstract: An apparatus having a container comprising a volume. The volume is configured to retain a single dose of a medication appropriate for a specific classification of a weight of a patient. A first indicia is disposed on an exterior surface of the container. The first indicia indicates a type of the medication. A second indicia is disposed on the exterior surface. The second indicia indicates the specific classification, wherein the container, pre-packaged with the single dose, is appropriate for a single use dosing of the patient having the specific classification.

Abstract: A method and system for proving a drug delivery device. The device comprises a drug delivery device housing and a medicament contained in the drug delivery device housing. A dose dial sleeve is positioned in the housing and is rotatable to set a non-inverted dose of the medicament contained in the medical delivery device. The non-inverted dose may be increased by turning the dose dial sleeve in a direction towards a user of the drug delivery device. The dose medicament may be decreased by rotating the dose dial sleeve in a direction away from the user.

Abstract: Disclosed herein are fastening features for cartridge assemblies that include coding features that help dedicate a medicament reservoir to specific injection devices. An exemplary cartridge assembly comprises a cylindrical inner surface for holding medicament and a cylindrical outer surface comprising a fastening feature having a first coding element protruding from the cylindrical outer surface. The coding element is configured to engage a complementary coding feature on the fastener on a dose setting member specifically configured to dispense the medicament, thereby allowing only the correct cartridge assembly to connect to the correct dose setting member.

Abstract: A medical syringe with a light source mounted on a distal end of the syringe to provide illumination of an injection site, a battery pack receiver configured to receive a battery pack with magnetic attraction a proximal end of the syringe, and a control circuit that is configured to illuminate the light source when the control circuit detects movement of the syringe and disconnects the battery from the light source either after a fixed period of time or after motion of the syringe ceases. Ideally the light source is a disc-shaped array of LED lights. The syringe is constructed of materials that can be sterilized.

Abstract: The invention relates to a device for administering a liquid drop by drop. This administering device comprises a packaging filled with the liquid, an outflow channel with an administering opening, and means connected to the outflow channel for opening the packaging, wherein the opening means and the packaging are movable relative to each other. The device can have means for receiving the packaging, which receiving means can be adapted to fix the packaging, wherein the opening means are then movable relative to the receiving means. The opening means can conversely also be fixed relative to the receiving means, wherein the packaging is then movable in the receiving means. The opening means can be formed by a sharp outer end of the outflow channel.

Abstract: A safety device to be used with a vial, or capsule, has a collar dimensioned to slidably fit about the body of the vial. Extending from the collar is a neck member that has connected to its other end a housing pivotable to a position along the longitudinal axis of the vial. A latch member having a lip is integrated to the neck member and extends out from the neck member in a direction towards the center of the collar. Neck member is fabricated to have an elastic characteristic so that if it is not biased by any external force, it will return to its original position. As the collar of the safety device is moved along the body of the vial, neck member is biased away from the vial as the latch member maintains contact along the outer surface of the vial, and then the outer surface of the hub formed at the top end of the vial.

Abstract: A fluid infusion device is provided. The fluid infusion device can include a fluid reservoir having a barrel portion and a housing defining a receiving portion for removably receiving the fluid reservoir within the housing. The housing can have a first side including a first engagement system that cooperates with the barrel portion to bias the fluid reservoir relative to the housing in a direction substantially opposite a direction of fluid flow out of the fluid reservoir.

Abstract: A cylindrical holder for housing a pharmaceutical product container in a hand-piece of a surgical instrument for perforating dense tissue of a human or animal body and injecting a pharmaceutical product behind or in the tissue. The cylindrical holder connects an injection needle with the container. The holder has a tubular wall for receiving the container. The tubular wall includes contact areas defined by bridges of material subsisting between cut-outs located along circumferential rows, the bridges of material having deflections towards the inside of the cylindrical holder. A surgical instrument for perforating dense tissue of a human or animal body and injecting a pharmaceutical product behind or in the tissue, and includes a hand-piece and the cylindrical holder.

Abstract: An adaptor top for a medicament cartridge, the medicament cartridge including a cylinder having a main body portion, a neck portion at a first end having a radially outwardly directed flange portion, a narrowing shoulder portion connecting the body portion and the neck portion, a cap beaded across the first end thereby to retain a fluid impermeable membrane, and the adaptor top comprising a first cylindrical body portion having a radially inwardly directed flange at one end, in use to be seated over and against the cap and a second cylindrical skirt portion being adapted, in use, to be seated against the shoulder portion of the cartridge, the second skirt portion including a plurality of fingers, the free ends of the fingers in use being adapted to be seated beneath the outwardly directed flange of the medicament cartridge.

Abstract: The present invention relates to a cartridge holder assembly for a drug delivery device comprising of a cartridge holder adapted to receive a cartridge filled with a medicament to be dispensed by the drug delivery device, wherein the cartridge holder comprises a first through opening at a distal end section to receive a piercing element adapted to penetrate a sealing member of the cartridge, a support structure adjacently arranged to the first through opening; and a constriction member arranged between the support structure and a distal end face of the cartridge and having a second through opening smaller than the first through opening.

Abstract: An ampoule holder for receiving an ampoule that has a closure element with a radial projection, the ampoule holder including an ampoule seat and a securing member operably coupled to the ampoule seat, wherein the radial projection of the closure element can be arranged between the ampoule seat and securing member.

Abstract: An injector including a syringe arranged along a longitudinal axis, a removable cover for removable engagement with the syringe and a cover removal assembly including an outer portion which is engagable by a user and is movable axially in a cover disengagement direction along an axial travel path with respect to the longitudinal axis and an inner portion which includes at least one engagement portion which is engagable with the removable cover, whereby axial movement of the inner portion in the cover disengagement direction removes the removable cover from the syringe, at least one of the outer portion and the inner portion being configured such as to provide an axially floating lost motion engagement between the outer portion and the inner portion.

Abstract: Various embodiments of piston rod assemblies, drug delivery devices making use of such piston rod assemblies, and methods for assembling such piston rod assemblies and drug delivery devices are provided. In one embodiment, a piston rod assembly for a drug delivery device is provided, wherein the piston rod assembly is configured to engage a piston of a medicament cartridge. The piston rod assembly comprises (i) a piston rod, (ii) at least one adjusting member displaceably engaged with a distal end section of the piston rod, wherein the at least one adjusting member is displaceable along a long axis of the piston rod, and (iii) at least one interlock member configured to mutually lock the at least one adjusting member and the piston rod in an arbitrary relative axial position.

Abstract: A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5?, 6, 6?) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27?, 28?) on the distal end of a cartridge assembly (20).

Abstract: An injection device having a distal end, and including a needle located inside the injection device in an initial position, wherein the needle is moveable to a puncturing position in which the needle projects from the distal end, an open region located distally relative to the needle in the initial position of the needle and having a dimension, and a reduction piece moveable relative to the opening region whereby the dimension may be reduced.

Abstract: A trigger operated syringe (100) for intramammary injection of antibiotics has a fluid containing syringe cartridge (203) activated by a plunger (206) which is inserted into the syringe cartridge (203A) and expels fluid when the trigger (205) is pulled. A syringe cartridge holding mechanism (223) holds the syringe cartridge in place until the trigger (205) is released and the plunger (206) retracted. Single syringe cartridge (203) and multiple syringe cartridge (204) versions are disclosed. The plunger moves in a direction which is effectively perpendicular to the direction of movement of the trigger, allowing for ease of injection to a cow's teats, and ejection of the spent cartridges.

Abstract: Injection systems comprising a powered injector and one or more hazardous agents are disclosed.

Abstract: A product dispensing apparatus including a reservoir module, a dosing module and a dose setting member. The reservoir module includes a front casing section, a block, a first connector, a piston, and a piston rod moveable in a dispensing movement and against the dispensing movement, and including a return block engageable with the block, wherein engagement between the block and the return block prevents the piston rod from moving against the dispensing movement. The dosing module includes a rear casing section, including a second connector which is engageable with the first connector to form a detachable connection between the reservoir module and the dosing module, and a dosing and drive device. The dose setting member engages the piston rod such that it is moveable together with and in the same direction as the piston rod during the dispensing movement and is moveable relative to the piston rod against the dispensing movement.

Abstract: A medication cartridge injection assembly facilitates and tracks dispensation of medication such as epinephrine during a heart attack. The assembly includes a frame and a housing having a plurality of chambers holding cartridges of medication. A barrel is coupled to the frame and selectively alignable with each chamber. A plunger is aligned with the barrel to engage the cartridge positioned in an aligned chamber. An actuator engages the cartridge upon manipulation of the actuator. A processor is operationally coupled to a timer actuated by manipulation of the actuator. An alert mechanism is operationally coupled to the processor to provide an alert related to a time expired since a most recent dispensing of medication.

Abstract: Drug delivery device comprising a cartridge holder adapted to receive and hold a cartridge in a loaded position, the cartridge holder comprising a distal opening adapted to receive the cartridge. The drug delivery device further comprises an expelling assembly adapted to engage and axially displace a piston in a loaded cartridge to thereby expel a dose of drug from the cartridge, and snap locking means acting on a cartridge being inserted in the cartridge holder, the snap locking means having a locked state in which the cartridge is held in the loaded position and an un-locked state in which the cartridge can be removed from the cartridge holder.

Abstract: A syringe carpule for storing, transporting and in situ mixing of a local anesthetic, such as lidocaine, and a buffer, such as sodium bicarbonate, and delivery of buffered anesthetic solution according to the present invention that comprises a hollow tubular body received within the frame of a carpule syringe, at least one axially movable plunger within the body and configured to be engaged and moved by a rod of the carpule syringe, a seal pierced by a rear portion of a needle coupled to the carpule syringe, a first chamber within the body filled with anesthetic solution during storing and transport, a second chamber defined within the body filled with buffering solution during storing and transport; and a breachable separating member between the first and second chamber configured to be removed for in situ mixing of the buffering and the anesthetic solutions allowing for delivery of a buffered anesthetic solution.

Abstract: Drug delivery system comprising a cartridge with an axially displaceable piston, and a front-loaded cartridge holder adapted to axially receive and hold a cartridge in a loaded position. The cartridge comprises first coupling means arranged at the distal portion, and the cartridge holder comprises second coupling means arranged at the distal portion, wherein the first and second coupling means are configured to engage each other to thereby axially secure a cartridge mounted in the cartridge holder.

Abstract: The invention pertains to an applicator (1) for inserting an implant, in particular a rod-like implant (2) containing an active substance, under the skin of a human or animal, comprising a housing (3), a cannula (6) extending from the housing (3), and a handle (15) for grasping and maneuvering the applicator (1) and the cannula (6) during insertion of an implant (2). In accordance with the invention, the handle (15) extends above at least part of the length of the cannula (6). Such a handle facilitates insertion of the cannula and/or accurate positioning of the implant.

Abstract: Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The housing cavity is arranged for receipt of a syringe suitable for use in the injected delivery of drug to a patient. The syringe has a barrel for containing a volume of a liquid drug formulation, the barrel defining an end flange at the rear end thereof and a forward shoulder at the forward end thereof. The cassette unit includes a sleeve form adapter arranged for receipt by the syringe barrel and to fit at least partly over the end flange of the syringe barrel. Accommodation of different syringe sizes within the same cassette unit geometry is achievable by selecting a sleeve form adapter tailored to the particular sizing of the barrel of each different syringe.

Abstract: Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes an annular groove formed in a distal end and adapted to receive a circlip disposed in a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.

Abstract: The present invention relates to a delivery member attachment device (10) comprising a neck (12) having an inner space intended to accommodate a connection part of a medicament container, which neck (12) is intended to receive a delivery member (30) for creating a passage between the medicament container via the connection part and through the delivery member, that said neck (12) is arranged with threads (14) arranged to engage with corresponding threads (34) of an attachment part (32 of said delivery member (30), and wherein said neck (12) further is arranged with a number of slits (16) providing a number of tongues (18) between said slits, and wherein said tongues (18) are arranged to flex inwards, when a delivery member (30) is to be attached, to allow an axial pushing of said attachment part (32) onto, and in engagement with, said neck (12).

Abstract: Infusion systems for pumping fluid into a body of a user, and methods for providing infusion systems, are disclosed. The infusion systems include an infusion pump, wherein the infusion pump comprises an infusion pump housing including a cavity. A fluid storage is removably inserted into the cavity of the infusion pump housing wherein, the fluid storage comprises a cartridge and an adapter connected to the cartridge such that the adapter encases the cartridge, and an infusion set is removably connected to the fluid storage.

Abstract: Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes an enlarged distal portion having a diameter greater than a diameter of the body. The enlarged distal portion has one or more resilient barbs adapted to engage a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.

Abstract: A delivery system for delivering a therapeutic agent to a patient includes a catheter, a stop feature, a container and a bar. The catheter has a proximal end and a distal end and includes a body defining a lumen that extends to the distal end of the catheter. The stop feature is in proximity to the distal end of the catheter. The container is configured to house the therapeutic agent and is insertable and slidably disposable in the lumen of the catheter. The container is also configured to engage the stop feature of the catheter. The bar is slidably disposable in the lumen of the catheter. Sliding of the bar distally in the lumen forces the therapeutic agent out of the container and out of the lumen when the container is engaged with the stop feature. The stop feature is configured to inhibit the container from exiting the lumen.

Abstract: The present invention relates to a cartridge holder for a drug delivery device comprising: a distal portion for receiving a cartridge filled with a medicament to be dispensed by the drug delivery device, wherein the distal portion comprises a mount for a piercing assembly, a proximal portion adapted to at least partially receive a drive mechanism having a piston rod to become operably engaged with a piston of the cartridge for expelling a dose of the medicament from the cartridge, wherein the drive mechanism comprises at least first fixing means corresponding with fixing means of the drive mechanism for directly interconnecting cartridge holder and drive mechanism.

Abstract: The present invention relates to a piston for a cartridge to be filled with a medicament, the piston comprising: a first piston member comprising a first material and forming a distal end face of the piston, a second piston member comprising a second material of lower compressibility compared to the first material, wherein the second piston member is arranged in a cupped receptacle of the first piston member and provides a thrust receiving surface at a proximal end of the piston.

Abstract: An injection device comprises a housing adapted to receive a fluid container having a discharge nozzle and a dispensing piston moveable in the fluid container to expel the contents of the fluid container out of the discharge nozzle. A drive is adapted on activation to act on the fluid container to advance it from a retracted position in which the discharge nozzle is contained within the housing to an extended position in which the discharge nozzle extends from the housing and act on the dispensing piston to expel the contents of the fluid container out of the discharge nozzle. A connector is adapted to receive a vial containing fluid and connect it to the discharge nozzle.

Abstract: An adapter for use with an appliance for administering an injectable product, the adapter serving to create a product connection between a catheter and a product container that can be inserted into the appliance, and including a thread for screwing the adapter to the appliance, a stop for fixing the container in the longitudinal direction of the thread, an attachment piece to which the catheter may be connected, and a product channel that extends through the attachment piece and the thread.

Abstract: An injection device having a delivery element with an inner thread may be driven by rotation and includes a cylindrical outer wall region, which is substantially smooth. Such features provide a delivery element configured such that it is less intimidating to patients than known threaded rods, and may facilitate easy cleaning. The delivery element may be non-rotatably guided and axially spring-loaded, and may be inserted axially into the housing when the reservoir is replaced. The driving thread element for the delivery element may be mounted in the vicinity of the distal end of the housing.

Abstract: An injection device has a dispensing chamber housing, a plunger, and a temperature control device. The dispensing chamber housing has a first part and a second part. The first part is thermally coupled to a needle. The second part is thermally coupled to the first part. The second part has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for holding a quantity of a substance. The plunger is engaged with an inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The temperature control device at least partially surrounds the dispensing chamber housing and is capable of altering a temperature of the substance in the dispensing chamber. The second part has a greater thermal coefficient than the first part.

Abstract: A drive assembly suitable for a medication delivery device comprises a housing, a drive member, a piston rod, a rotation sleeve, a guide member and a biasing member. The rotation sleeve is arranged to be displaced in a distal direction when the drive member is displaced in the distal direction by mechanical interaction of the drive member and the rotation sleeve with the rotation sleeve and the drive member both being guided axially by the at guide member. The biasing member exerts a force on the rotation sleeve acting in the proximal direction, said force being transformed into a rotational movement of the rotation sleeve. The rotational movement of the rotation sleeve being transformed into a rotational movement of the piston rod.

Abstract: Described herein are injection devices capable of automatically injecting substances into the soft tissue of a patient. The devices can inject low to high viscosity materials at predetermined, user selected injection rates, allowing the operator more control than a traditional syringe. The devices can allow mixing of more than one substance and/or reconstitution of a solid substance for injection. The injection devices described herein can allow the operator to easily inject one or more low to high viscosity liquid or gel soft-tissue augmentation fillers, one or more drugs, one or more other biocompatible materials, or combinations thereof.

Abstract: A medication administering device has mounted thereto a preparation syringe containing a preparation and comprises a substantially cylindrical syringe cover that supports the preparation syringe on the inner peripheral face side, a piston that presses on the rear end of the preparation syringe, and a piston case that surrounds the piston, that guides the outer peripheral face of the syringe cover in the direction of the piston on the substantially cylindrical inner peripheral face side, and that is mounted in a state in which the syringe cover is removable. The medication administering device comprises a syringe holder that guides the outer peripheral face of the preparation syringe in the direction of the piston on the cylindrical inner peripheral face side, and whose outer peripheral face is removably fitted together with the inner peripheral face of the syringe cover.

Abstract: The invention refers to a method and an element for biasing a cartridge in a drug delivery device. The element for biasing the cartridge in a cartridge housing of a drug delivery device and an according system comprising the element and the drug delivery device are provided which is a self retained element comprising a first member having a shape that allows passage of a spindle of the drug delivery device. The self retained element biases the cartridge against an inner surface of the cartridge housing. This cartridge could be a removable cartridge.

Abstract: A device for delivering fluid, comprising an elongated outer casing (10) provided with a substantially cylindrical inner chamber (11); a plunger (21) movable axially along a longitudinal axis A-A of an inner reservoir (22) towards an outlet (28); an actuator comprising a multi-stage lead-screw with a plurality of coaxial, screwably-interconnected bushings and an output spindle or an output bushing linked to the movable plunger (21), whereby a rotation of the rotating element causes a translation of the bushings relative to each other in telescopic fashion, and a translation of the movable plunger in the cartridge.

Abstract: A cap for a cartridge having a bead at the distal end is disclosed. The cap comprises: a main body having a proximal end, a distal end, and a bore that receives the cartridge, the main body further comprising a first segment and a second segment; and a retention feature on the main body suitable for snapping under the bead of the cartridge for securing the cap to the cartridge.