Abstract: A hand-held applicator is defined for applying a viscous product, such as a pharmaceutical product to the skin. The applicator includes a substrate with a flat face defining multiple dosing areas of the product. The product can be dispensed from a tube in a first area for a first recommended dosage and in combination in a first area and a second area for a second recommended dosage. Once the desired dosage is dispensed, the applicator is used to apply to product to an affected area of the skin.

Abstract: A face mask that has tab parts at opposing positions approximately on an upper side of the face shape, and a ridge-folded part and a valley-folded part are alternately folded in a lateral direction of the face and further folded perpendicularly to these folding lines, where the tab parts are folded in a manner projecting outward, so that the face mask having such fold structures can easily be spread out.

Abstract: Embodiments described herein generally relate to improved devices, systems, kits, products and methods related to topical medicament application of measured dosages. The kits and devices can single use and/or disposable for example.

Abstract: An ocular device for insertion into an eye is provided and includes a body having an anterior surface and a posterior surface for placement on one of superior sclera and inferior sclera of the eye. The posterior surface is defined by a base curve that is substantially identical to a radius of curvature of the one of the superior sclera and inferior sclera of the eye. In one embodiment, the ocular device serves as an ocular drug delivery device and contains an active pharmaceutical agent, a lubricant, etc.

Abstract: A system for delivering moisturizing liquid to the lips of a subject includes an applicator for applying the moisturizing liquid to the lips supported by a support structure so that at least a part of applicator is deployed so as to engage a recess between the lips of subject without obstructing contact between the subject's upper and lower lips. The proximity of the applicator to the lips allows the use of simple contact-based implementations of the applicator. At the same time, disruption of speech and other normal oral movement is minimized by avoiding any obstruction to contact between the lips.

Abstract: A clamp and handle is designed exclusively for holding purchased containers of rub on and roll on pain killers, deodorants and any other substance that is in a container with a built in applicator. The handle is for applying these substances to hard or impossible places to reach due to anatomy or injury. The clamp, handle and knob are constructed from PVC that has a smooth glossy finish for the purpose of not causing any injury. The PVC can move smoothly over skin. The knob is flower shaped to make it easier to grip. The knob and clamp body prevent the stainless steel screw from scratching any skin. The screw will never rust.

Abstract: An abdominal wound dressing and methods of use are described that enable the application of negative pressure to the wound site in a healing manner while also limiting the formation of adhesions that would prevent the removal of the dressing. The dressing comprises a layer of porous foam material enclosed by sheets of elastomeric material punctuated by a number of appropriately placed holes. Multiple layers of porous foam may also be used. A suction tube connector is provided on an upper surface of a layer of foam for connection to a negative pressure source. At least one layer of foam is enclosed in elastomeric material and is placed in direct contact with the tissue within the open wound. Fluids are drawn by negative pressure through the holes positioned in the elastomeric envelope and through the foam.

Abstract: The present invention provides devices, systems, and methods for delivery of an active agent into the eye of a subject. In one aspect, for example, an ocular active agent delivery device (10) can include an active agent reservoir (14) disposed in an annular housing (12), the annular housing (12) being configured to fit inside of a lens capsule and at least partially encircling a line of sight of an intraocular lens within the lens capsule. The device (10) can further include a semipermeable membrane (16) operatively coupled to the active agent reservoir (14), where the semipermeable membrane (16) is configured to allow diffusion of an active agent from the active agent reservoir (14). Additionally, a valve (18) can be operatively coupled to the active agent reservoir (14), where the valve (18) is configured to allow filling of the active agent reservoir (14) with an active agent.

Abstract: Methods for promoting angiogenesis comprising administering platelet-rich plasma to a site and stimulating the site with an electromagnetic field. Platelets include platelet-rich plasma and compositions can further include stem cells such as adipose stromal cells and cells derived from bone marrow aspirate. Methods also comprise isolating platelets from a patient's blood, forming a composition including the platelets, delivering the composition to a site in need of treatment, and electrically stimulating the site.

Abstract: A water based polymeric dispersion for PSA adhesive preparation for transdermal system comprising: a) an aqueous dispersion of a polymer of an acrylate and/or a methacrylate ester, b) a plasticizer c) a shrinkage reducing agent able to reduce the shrinkage of the water PSA dispersion when spread onto a surface to width values lower than 20 mm after 3 minutes rest.

Abstract: A wound treatment system including a treatment chamber, a source of an aqueous antibiotic, a source of an oxygen-enriched gas, and a control system adapted to alternately surround a human limb with antibiotic mist and the oxygen enriched gas, which can be used to heal lesions such as foot ulcers. A method of treating lesions such as foot ulcers is also disclosed, that includes bathing the lesion in antibiotic mist and contacting it with oxygen gas.

Abstract: Disclosed are devices for urine voiding postponement, and methods for treating conditions such as central diabetes insipidus, enuresis, nocturia, urinary frequency or incontinence. The devices deliver a desmopressin flux through the skin of a patient in a low dose amount just necessary to achieve a desired anti-diuretic effect without undesirable side effects such as hyponatremia. The devices are designed to permit a state of normal urinary production to return quickly after the desmopressin flux is terminated.

Abstract: A brush implement for the use with a skin treatment device, the brush implement having bristles of a first type and bristles of a second type, wherein the bristles of the first type are longer than the bristles of the second type and are positioned closer to the outer contour of the brush implement and the bristles form at least three distinguishable sectors.

Abstract: A containment arrangement for safely and effectively treating a wound on a patient without contaminating attending personnel. The arrangement comprises a patient receiving first enclosure having a patient contacting periphery, a pressurizable source in communication with the patient through a wall of the enclosure for enlarging the enclosure, and a sealing means arranged in the patient contacting periphery. A hand manipulable fluid discharge nozzle is extendably arranged through the enclosure for providing controllable treatment fluid to the wound on the patient within the enclosure.

Abstract: Cellulite is treated by severing septae, which interconnects the skin with the underlying muscle. The septae may be severed in connection with a liposuction procedure or independent of a liposuction procedure.

Abstract: Strip-shaped forms of administration for administering an active ingredient via the mucous membrane of the gums.

Abstract: A smoke capture adapter comprising: a first adapter part having a first generally ring-shaped portion with a first cylindrical inner surface for securely engaging a laser apparatus having a beam propagation axis, the first generally ring-shaped portion being oriented such that the beam propagation axis passes through a region bound the first generally ring-shaped portion and a tubular outlet extending from said first generally ring-shaped portion for communicating with a vacuum tube; a second adapter part rotatably connected to the first adapter part and arranged to rotate generally about the beam propagation axis having a second generally ring-shaped portion adjacent the first generally ring-shaped portion, the first and second generally ring-shaped portions defining a generally toroidal cavity and an inlet in fluid communication with the cavity; the tubular outlet and inlet in fluid communication through the cavity; whereby the position of the inlet relative to the first adapter part may be adjusted by rota

Abstract: A transdermal permeant delivery system for delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.

Abstract: A portable system for subatmospheric pressure therapy in connection with healing a surgical wound, includes a wound dressing dimensioned for positioning relative to a wound bed of a subject, a portable subatmospheric pressure mechanism dimensioned to be carried or worn by the subject and a container for collecting exudates from the wound bed removed under the subatmospheric pressure supplied by the subatmospheric pressure mechanism. The portable subatmospheric pressure mechanism includes a housing, a subatmospheric pressure source disposed within the housing and in fluid communication with the wound dressing to supply subatmospheric pressure to the wound dressing and a power source mounted to or within the housing for supplying power to actuate the subatmospheric pressure source.

Abstract: Methods and devices are provided for activating brown adipose tissue with targeted substance delivery. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a chemical configured to stimulate nerves that activate the BAT and/or to stimulate brown adipocytes directly can be delivered to a patient, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure. The chemical can be delivered to the patient locally and/or systemically to stimulate the nerves and/or the brown adipocytes.

Abstract: Disclosed are devices, methods and systems for treatment of eye disease such as glaucoma. Implants are described herein that enhance aqueous flow through the normal outflow system of the eye with minimal to no complications. The implant can be reversibly deformed to a first shape, such as a generally linear shape conducive to insertion. Upon insertion, the implant can deform to a second shape, such as a generally non-linear shape conducive to retention within the eye. The shape also improves fluid flow from the anterior chamber and prevents or reduces clogging.

Abstract: An insect-bite itch stopper is disclosed which has a pressure surface adapted for pressing directly onto an insect bite and an applicator for simultaneously or contemporaneously applying an anti-itch medication to the bite.

Abstract: A suction device according to the present invention has: an outer tube connected to a fluid supply unit on a base-end side thereof and including an opening edge section; and a suction tube provided in the outer tube and connected to a negative pressure generating unit on a base-end side thereof, the suction tube including an opening edge section, wherein an annular fluid supply passage is formed between an inner peripheral surface of the outer tube and an outer peripheral surface of the suction tube, and the opening edge section of the suction tube is placed inside the opening edge section of the outer tube toward the base-end side thereof.

Abstract: The present invention is a tension relief bag that includes a plurality of washing soap intended to be used by a human, a two-sided cloth containing pouch with a tucked in flap that contains the washing soap and a flap that is disposed of the containing pouch. The tension relief bag can utilize washing soap that is a plurality of shredded soap or one or more bars of washing soap. The tension relief bag flap can be tucked into the containing pouch or be releasable secured to the containing pouch with a tucked in flap.

Abstract: A cotton swab and cotton swab holder, which can be used together in a cotton swab holder assembly. The cotton swab having a shaft and a cotton portion disposed on an end of the shaft. The cotton swab holder having a handle portion; and a cotton swab holding portion connected to the handle portion, the cotton swab holding portion having a mechanism for holding the shaft of the cotton swab. Also provided is a cotton ball including: a cotton body; a wall defining a cavity disposed on an interior of the cotton body; and one of a liquid or gel contained in the cavity.

Abstract: A lotion application compartment (10) includes an apparatus for topical application of a fluid to a human or animal body. The apparatus includes a spray nozzle (20) and a support (80) for the body. The apparatus further comprises of one or more of the following: a structure for moving the support, so as to change the distance between the body and the spray nozzle (20); a structure for varying the spray pattern, spray pressure, spray frequency and/or spray duty cycle of the nozzle (20); a structure for varying the rotational speed of the support (80); and a structure for raising the body's skin temperature directly by radiation. A lotion application compartment (10) consisting of apparatus for topical application of a fluid to a human or animal body, the apparatus comprising a spray nozzle (20) and a support (80) for the body.

Abstract: Methods and apparatus for treatment of dry eyes by providing a single apparatus for measuring the diameter of the lacrimal punctum and, based on the measured punctal diameter, inserting therein an appropriately sized punctum plug.

Abstract: A wound shield may include a conformable frame to circumscribe a wound. Any suitable dressing may be secured over the conformable frame providing separation between the wound and the dressing. The wound frame may provide pressure relief around a wound or pressure sore to permit healing, allow compression for venous ulcers, retain moisture within the wound environment, absorb exudate, relieve pain and trauma associated with dressing removal, allow debridement and application of topical medications and or other compounds or chemicals, accelerate healing and facilitate monitoring of wounds. A conformable frame may be composed of one or more layers of any suitable material and may include adhesive on one or more surfaces to secure the frame to the wound site, to secure the frame to itself and or any suitable closure element and or to secure the dressing to the conformable frame. A wound shield may be used for humans or any suitable animal.

Abstract: A body piercing cleansing and sanitation device is described, which is self-contained and pressurized. The device improves and simplifies the cleaning process, ensuring thorough sanitation through the piercing hole, the external surface of the piercing, and the body ring without needing to remove the body ring.

Abstract: A reduced-pressure treatment system for applying reduced pressure to a tissue site at a limited-access location on a patient includes a reduced-pressure source, a treatment manifold for placing proximate the tissue site and operable to distribute reduced pressure to the tissue site, and a sealing member for placing over the tissue site and operable to form a pneumatic seal over the tissue site. The reduced-pressure treatment system also includes a reduced-pressure bridge and a moisture-removing device on at least portion of the reduced-pressure bridge. The reduced-pressure bridge includes a delivery manifold operable to transfer the reduced pressure to the treatment manifold, an encapsulating envelope at least partially enclosing the delivery manifold and having a patient-facing side, and a reduced-pressure-interface site formed proximate one end of the reduced-pressure bridge.

Abstract: A wound treatment arrangement for the debriding and cleansing of a patient's body portion comprising: a flexible elongated body portion enclosure bag; an elongated nozzle arrangement securable to the inner surface of the elongated enclosure bag; a pressurized fluid treatment supply gun; and a connectable and releasable coupler member arranged on the proximal end of the nozzle arrangement so as to sealably receive a corresponding coupler arrangement on the fluid treatment supply gun.

Abstract: The invention provides a sanitary pad that protects and promotes hygiene. The Clean Seat Undie Protector is an improved sanitary pad for dealing with incontinence issues. The Clean Seat comes in different sizes to accommodate the various needs of the consumer and to allow for different types of female and male underwear. The present invention adhesively attaches to the inside of one's underwear. The Clean Seat pad is fabricated with a cotton absorbable material to contain accidental leaks or discharges. The absorbent pad comprises a water resistant sheet with a peel off adhesive strip and cover on one side.

Abstract: The Holistic Breast Patch is the first known, non-pharmaceutical, effective device available which inhibits prolactin production safely and aids the relief of discomfort from breast engorgement pain by drying breast milk after pregnancy. The benefits of treatment of prolactin dependent diseases remain to be fully disclosed. It works transdermally and is comprised of a unique, approximately 1½ inch by ¾ inch natural and organic carbonyl disc housed within cotton gauze and nonstick adhesive Telfa®. It meets the Federal Drug Administration's definition of a non-significant risk device (21 CFR 812). Its use will aid in the treatment of prolactin dependent diseases and conditions and eliminate the serious risks of health complications and fatalities that have been documented by the use of prescription drugs, hormones and pharmaceuticals lacking FDA approval for this use by women. Wearing the Patch device is both easy and convenient.

Abstract: A wound shield including a conformable frame to circumscribe a wound and warm water circulating system to maintain a warm environment. Any suitable dressing may be secured over the conformable frame providing separation between the wound and the dressing. The wound frame may provide pressure relief around a wound or pressure sore to permit healing. A conformable frame may be composed of one or more layers of any suitable material and may include adhesive on one or more surfaces to secure the frame to the wound site and or to secure the dressing to the conformable frame.

Abstract: A portable system for subatmospheric pressure therapy in connection with healing a surgical wound is provided. The system includes a wound dressing dimensioned for positioning relative to a wound bed of a subject, and a collection canister in fluid communication with the wound dressing. The canister includes a base defining a fluid receiving cavity and having a fluid inlet port and a vacuum port. The fluid inlet port is configured for fluid communication with a wound dressing, The system further includes a cover selectively engageable to the base, e.g., in a snap-fit manner. The cover is configured to receive a control unit and has a vent assembly for exhausting the control unit. A seal member is interposed relative to the base and the cover to establish and maintain a substantial sealed relationship between the two components when assembled.

Abstract: Apparatus (130) for use in wound therapy of mammals is described, the apparatus (130) comprising: a dressing covering the wound, the dressing being substantially sealed to prevent ingress of ambient atmospheric air to the wound; aspiration means (132) operably connected to a space between the dressing and the wound by an aspiration conduit (142) sealed to the point of entry between wound and dressing against ingress of ambient atmosphere, said conduit (142) being for aspiration of said wound and for removal of fluid from said space between said wound and said dressing; a waste container (148) for receiving aspirated fluid to be discarded operably connected to said aspiration conduit; and heating means (144) for heating said fluid in order to increase the vapor pressure thereof and to cause evaporation to reduce the volume of the fluid in the waste container (148). In a preferred embodiment of the present invention the waste fluid is also provided with a sparge gas.

Abstract: An embodiment of an apparatus for extracting excess liquid in a human body spray system includes a spray booth defining a booth volume. The spray booth includes a base configured to support the human body and a column having walls extending vertically from the base and at least one vent opening disposed on a bottom half portion of the column on at least one of the walls. The walls form a hollow interior of the column. The apparatus for extracting excess liquid in a human body spray system further includes an extraction fan disposed within the hollow interior adjacent to a top half portion of the column and configured to create a low pressure volume within the hollow interior and draw air flow and at least some of the excess mist from the booth volume through the at least one vent opening.

Abstract: The present invention relates generally to the treatment and eradication of lice. More particularly, the present invention relates to a system and method for treatment and eradication of lice through the submersion of an infected area in a liquid solution.

Abstract: The invention is a transdermal patch containing a noradrenergic and specific serotonergic antidepressant (NaSSA) such as mirtazapine or the like as the active ingredient therein, and capable of transdermally and quantitatively administering the active ingredient. Further, the transdermal patch of the invention exhibits a sufficient therapeutical effect, can suppress side effects that are problematic in oral administration, improves patient compliance and quality of life (QOL), and can solve various problems. Preferably, the patch provided by the invention contains the active ingredient in an amount of from 2 to 30% by mass relative to the drug-containing layer.

Abstract: A wound treatment apparatus comprises: a fluid drainage tube configured to be coupled to a fluid drainage passageway of a wound bandage; first and second fluid drainage receptacles coupled to the drainage tube; and first and second valves coupled between the fluid drainage tube and the first and second fluid drainage receptacles, respectively.

Abstract: A topical anesthetic dispenser is releasably attachable to a pre-filled disposable syringe. A clip receives a barrel of the syringe. The clip includes a receptacle portion receiving a pre-filled cannister of a topical numbing agent, wherein the cannister includes a generally cylindrical chamber portion receivable within the receptacle portion of the clip and a distal neck portion having an outlet allowing contents of the cannister to be dispensed. A dispenser attached to the distal neck portion of the cannister includes an elongated flexible tube surrounded by a rigid tube for at least a portion of a length of the elongated flexible tube. A pivotable lever carries a tube compressor including a pinching member extending through an opening in the rigid tube and spring biased to a position at which the pinching member pinches closed an elongated passageway through the flexible tube.

Abstract: A topical anesthetic dispenser is releasably attachable to a pre-filled disposable syringe. A pair of clips receive a barrel of the syringe. The clips are on a housing receiving a pre-filled cannister of a topical numbing agent and including a chamber. The cannister includes an aerosol dispensing valve actuated by a button which when pressed moves the cannister with respect to an actuator for the valve.

Abstract: Dressings, systems, and methods are disclosed in some embodiments that involve treating a tissue site with reduced pressure wherein the dressing includes a dressing reduced-pressure indicator that allows one to ascertain that the reduced pressure applied at the dressing is greater than a threshold reduced pressure. The dressing reduced-pressure indicator may include a moving member that is adapted to move under reduced pressure and a visual indicator associated with the moving member. Another embodiment uses an electro-mechanical indicator to provide a powered visual alert or audible alert or another output signal. Other dressings, systems, and methods are disclosed.

Abstract: This disclosure relates generally to electrosurgical methods and devices. In some embodiments, an electrosurgical system/device is provided suitable for applying phase controlled RF energy to a treatment site. The electrosurgical device comprises a multi-electrode electrosurgical probe electrically coupled to a plurality of RF generators. Also provided are methods of use of such an electrosurgical device, as well as other electrosurgical devices. The methods and devices disclosed herein find utility, for example, in the field of medicine.

Abstract: A personal skin polishing or microdermabrasion device having a convenient form factor with a applicator attached to a contoured housing with a handle portion. The housing contains a battery, a cordless motor and a gear box to provide an appropriate rotational velocity to the output shaft that is coupled to the applicator. The applicator may be a foam material selected to cushion the skin from excessive abrasion to the particles in a personal care composition to be used with device, and to have a porosity that will enable the foam to interact with the particles and enhance the skin polishing effect.

Abstract: An aspiration flow control device includes a housing having at least one vacuum port, at least one aspiration port, and an ejection port. The at least one vacuum port is adapted to be connected to a vacuum source, and the aspiration port is adapted to be connected to an aspiration line for receiving fluids from a surgical site. The device further includes a rotating structure having at least three vanes, which structure is configured to rotate within the housing. The at least three vanes divide an enclosed volume within the housing into at least three rotating fluid collection chambers. During rotation of the rotating structure, at least one fluid collection chamber is in communication with at least one vacuum port and the aspiration port through which fluid is received, and at least one other fluid collection chamber is simultaneously in communication with the ejection port through which fluid is expelled.

Abstract: A device for treating at least one infected nail of at least one digit of a subject includes an enclosure sized for housing at least a distal end of at least one digit of a subject having at least one infected nail. The enclosure comprises an integrally molded elastomeric polymer sheath having an interior cavity, which substantially conforms to the size and shape of at least the distal end of the at least one digit of the subject having the at least one infected nail. The sheath has an open end and a closed end, tapering from the closed end to the open end. The elastomeric polymer sheath comprises an elastomeric polymer film having oil resistance and low oxygen permeability. A method of using the device to treat the infected nail is provided. A kit including the device and an antifungal treatment composition is disclosed for treating the infected nail.

Abstract: A liquid streaming device and method of using same for treating a wound includes a body having a lower surface for application to skin region around the wound to be treated and to conform to the contour of the skin region, and an upper surface facing outwardly when the body is applied to the skin region; a recess formed in the lower surface of the body and configured to enclose the wound when the body is applied to the skin region, and to define a chamber closed on one side by the skin region and the wound, and on the opposite side by the body; an inlet in the body on one side of the recess for introducing a treating liquid into an inlet side of the chamber; and an outlet in the body on another side of the recess for outletting the treating liquid from an outlet side of the chamber.

Abstract: Described herein is an automated fluid drain control apparatus and method which comprises a first collection chamber which is connected to a drain that has been inserted into the subarachnoid area in lumbar region of the body. The volume of fluid into the first collection chamber is controlled as a function of time by being constantly measured such that too much fluid will not be drained from the body.

Abstract: The invention can be used to produce environmentally friendly toilet paper in which the use of natural materials such as paper and/or cellulose and/or cotton is reduced. The essence of the first embodiment of the invention: the toilet paper using polymeric materials is a sheet made of at least one polymeric material and/or at least one material containing at least one polymeric material, herewith at least one side of specified sheet is coated completely or partially by material or material comprising paper and/or cellulose and/or cotton, herewith at least one polymeric material used in specified toilet paper is completely or partially water-soluble. The essence of the second embodiment of the invention: in the toilet paper using polymeric materials a part of a side of toilet paper sheet is coated with polymeric material and/or material containing polymeric material.