Abstract: Exemplary embodiments allow a user to create configurations for use in distributed computing environments. Configurations can be arranged in hierarchies in which elements of the hierarchy can inherit characteristics from elements in other layers of the hierarchy. Embodiments also allow a user to flatten a hierarchical configuration to remove hierarchical dependencies and/or inheriting capabilities of elements in the hierarchy. Exemplary embodiments further allow users to deploy a distributed computing configuration on their desktop to evaluate performance of the configuration and then deploy the configuration in a distributed computing environment without having to change programming code run on the desktop/distributed computing environment.

Abstract: Functional imaging information is used to determine a probability of residual disease given a treatment. The functional imaging information shows different characteristic levels for different regions of the tumor. The probability is output for planning use and/or used to automatically determine dose by region. Using the probability, the dose may be distributed by region so that some regions receive a greater dose than other regions. This distribution by region of dose more likely treats the tumor with a same dose, allows a lesser dose to sufficient treat the tumor, and/or allows a greater dose with a lesser or no increase in risk to normal tissue. The dose plan may account for personalized tumors as each patient may have distinct tumors. Probability of dose application accuracy may also be used, so that a combined treatment probability allows efficient dose planning.

Abstract: Methods and systems described herein include beverage immersates and methods of their use. Systems include: at least one beverage immersate, wherein the at least one beverage immersate includes at least one sensor configured to detect at least one analyte in a fluid within a personal use beverage container; and at least one signal transmitter configured to transmit a signal responsive to the at least one beverage immersate. Methods include: detecting one or more analyte in fluid within a personal use beverage container with at least one sensor integral to at least one beverage immersate; and communicating data from the at least one beverage immersate to at least one device external to the beverage immersate.

Abstract: An apparatus arranged to give an output indicative of lung disease state, in particular Chronic Obstructive Pulmonary Disease (COPD). The apparatus comprises a biomarker detection unit; a patient information input unit; a memory unit; a processing unit; and an output unit. The biomarker detection unit generates biomarker information by analyzing a patient saliva sample. The biomarker information is processed with patient information relating to patient symptoms, and an appropriate output generated based on the combination of the biomarker information and the patient information. The output suitably indicates whether there is a change in the disease state, and may further include a recommendation regarding treatment for the disease according to such a change.

Abstract: The present invention relates to a system for optimizing and controlling the particle size distribution and scale-up of production of nanoparticle in an aerosol flame reactor. The method provides nanoparticles with desired, optimized and controlled particle size and the specific surface area in aerosol reactors using a simulation tool with programmed instructions. The simulation tool couples flame dynamics model and particle population balance model.

Abstract: The present invention is mainly intended to provide a reaction apparatus that can prevent a problem due to heat generated by heat treatment in a reaction part, and accurately perform detection, and the reaction apparatus is provided with: a reaction part that is introduced with sample gas having passed through a column and reaction gas, and as a result of a reaction between the sample gas and the reaction gas, produces measurement gas containing a predetermined compound; a protruding pipe that is integrally protruded from the reaction part; and a connecting part that is disposed separately from the reaction part and removably fitted with the protruding pipe.

Abstract: A system and method for evaluating drug data sets is provided. The system and method includes identifying when entries in a current data set differ from a data set comprising an aggregate of entries for a plurality of institutions, and prompting a user to determine if a change in the current data set should be changed. The system and method also identifies cases where different dose units are used for the same drug. A report is generated noting exceptions.

Abstract: An object of the present invention is to appropriately and easily evaluate a photosynthetic function of a photosynthetic sample contained in an evaluation sample. An evaluation method for photosynthetic sample according to the present invention is for evaluating a state of a photosynthetic sample with a photosynthetic function based on temporal data of a luminescence amount of delayed luminescence emitted from the photosynthetic sample. First, characteristic values that indicate characteristics are determined for a plurality of time periods in the temporal data. An evaluation value is then computed by weighting the characteristic values. The state of the photosynthetic sample is then evaluated based on the evaluation value.

Abstract: Continuous glucose monitoring (CGM) data and insulin delivery data are used to generate more reliable projected alarms related to a projected glucose levels. A memory stores endogenous data related to measurements of glucose level in a patient, and also stores exogenous data, such as insulin on board, both of which are used by a processor to create projected alarms. Profiles of CGM data are created for use in tuning patient-specific insulin data, such at basal rate, carb ratio, and insulin sensitivity. A processor searches for patterns in the data profiles and if found, recommended changes to patient-specific insulin data are provided to permit more accurate control over a patient's glucose levels.

Abstract: A method of analyzing a numeric model for a metal hydride tank, which calculates the temperature change and the change of a reaction rate and the hydrogen concentration in the alloy resulting from a hydrogen reaction based on various user conditions with respect to metal hydride (MH) alloy tanks having various shapes when MH alloy tanks are actually used. The method includes (a) inputting a temperature (T), a real reaction flow rate (QR), and an initial data value of hydrogen concentration (C) for each cell of a model, (b) calculating a possible reaction rate (RP) depending on the temperature (T) and the hydrogen concentration (C) in the metal hydride alloy with respect to each cell, (c) calculating a possible flow rate (QP) with respect to an entire MH alloy region, and (d) calculating a k between the real reaction flow rate (QR) and the possible reaction flow rate (QP).

Abstract: A method for analyzing a fluid containing one or more analytes of interest includes; measuring a plurality of properties of a sample fluid with unknown concentrations of the one or more analytes of interest; and using the measurements and a model of the relationship between the plurality of properties and concentrations of the one or more analytes to calculate the concentration of at least one of the analytes of interest. The model may be an artificial neural network. The method may be used to monitor the concentration of inhibitors of gas hydrate formation in a fluid. Apparatus for use in the method is also provided.

Abstract: A method of obtaining a fugitive emission flux measurement of airborne matter is provided. The method involves measuring the airborne matter along one or more than one measurement surface that spans the fugitive emission using two or more than two measurement beam paths where each of the two or more than two measurement beam paths are parallel to each other, or substantially parallel to each other, and determining a mass per unit length measurement for the measurement surface, determining a representative wind velocity at or near the one or more than one measurement surface, and calculating the fugitive emission flux of the airborne matter in mass per unit time using the mass per unit length determination and representative wind velocity.

Abstract: Disclosed is an auxiliary diagnostic apparatus including: a vector input unit that reads a test vector which is a spectral property vector of a biological tissue targeted for a diagnosis; a multiple linear regression analysis unit that executes a multiple liner regression analysis for the test vector with a plurality of individual component vectors which are spectral property vectors of particular substances, and obtains an error vector which is a vector of a residual error component; and an indicator calculation unit that extracts a feature of the error vector, and, from the extracted error vector, calculates an indicator representing whether an affected area is included in the biological tissue targeted for the diagnosis and which type of affected area has a possibility of being included in the biological tissue.

Abstract: A computer-implemented system and method for improving glucose management through cloud-based modeling of circadian profiles is provided. For each daily meal period, two sets of pre- and post-meal period data that include a blood glucose level and a diabetes medication dosing are stored into a circadian profile for a diabetic patient in a cloud computing infrastructure. Predicted blood glucose is modeled over the infrastructure and the access will be validated. A model, including expected blood glucose values and their predicted errors is created from the blood glucose levels in each profile and visualized in a log-normal distribution. Target ranges for blood glucose are determined and superimposed over the expected values. Pharmacodynamics of the medication are obtained. An incremental change in dosing of the medication is propagated over a model day and the expected blood glucose values and their predicted errors are adjusted in response to the incremental dosing change.

Abstract: Methods and apparatus for LC/IMS/MS analysis involve obtaining noisy raw data from a sample, convolving the data with an artifact-reducing filter, and locating, in retention-time, ion mobility, and mass-to-charge-ratio dimensions, one or more ion peaks of the convolved data.

Abstract: The present teachings provide a system for modifying insulin therapy support parameters such as warning limit data and time block data on a hand-held diabetes management device. The system can include a graphical user interface module that creates a graphical user interface having a plurality of bar structures positionable on or between a first line that indicates an upper limit and a second line that illustrates a lower limit. Each of the bar structures can have a first side that indicates a start time of a time window opposite a second side that indicates an end time of the time window and a third side that indicates a lower target value for a blood glucose level opposite a fourth side that indicates an upper target value for the blood glucose level. The bar structures, the first line and the second line can be adjustable by a user input.

Abstract: A control system for optimizing a chemical loop system includes one or more sensors for measuring one or more parameters in a chemical loop. The sensors are disposed on or in a conduit positioned in the chemical loop. The sensors generate one or more data signals representative of an amount of solids in the conduit. The control system includes a data acquisition system in communication with the sensors and a controller in communication with the data acquisition system. The data acquisition system receives the data signals and the controller generates the control signals. The controller is in communication with one or more valves positioned in the chemical loop. The valves are configured to regulate a flow of the solids through the chemical loop.

Abstract: A medical device and a method for displaying medical data by the medical device are disclosed. In one aspect of the disclosure, a method for displaying medical data by a medical device having a display device and one or more processors is disclosed. The method includes monitoring a condition of the display device and determining, at the medical device, whether the display device is in a failure state based on the monitoring, the failure state being indicative of a malfunction of the display device. When the display device is a failure state, the method includes commanding a slave device to display the medical data and providing the medical data from the medical device to the slave device for display by the mobile device.

Abstract: The present invention provides a method of determining the optimal composition of a serum-free, eukaryotic cell culture medium supplement, using 2-level factorial design and the steepest ascent method. The invention further provides a method of making a serum-free eukaryotic cell culture medium supplement and the generated thereof. The invention further provides a method of making a serum-free, eukaryotic cell culture medium and the medium generated thereof. The invention further provides a kit containing the medium of the invention. The invention also provides a method of expanding CD34<+> hematopoietic cells and a composition comprising CD34<+> hematopoietic cells in a serum-free, eukaryotic cell culture medium of the invention.

Abstract: A method, a system and an apparatus for predicting and/or recognizing and/or classifying biological sequences, specially sequence families with binding site recognition motifs poorly conserved, comprising, advantageously, the use of neural networks rules; providing enhanced and more accurate results; and is preferably used when the biological sequence is a promoter.

Abstract: An Anti-Terrorism water quality monitoring system for continuously monitoring a potable water treatment system and related potable water distribution network that provides potable water to a municipality, city, housing development or other potable water consumer. The system includes the collection of data from the water distribution system and from the water treatment facility and from advanced separation processes which are integrated into analytical instruments. The data collected are stored in a remote database on a remote server computer or bank of computers and accessible by Homeland Security or its designated agency. Preferred parameters of monitoring include the turbidity and disinfectant such as chlorine, hypochlorous acid, sodium hypochlorite, calcium hypochlorite, ozone, chlorine dioxide, chloramines, hydrogen peroxide, peracetic acid.

Abstract: A method and system for controlling a temperature of an exhaust gas being introduced to a catalyst is provided. Using an adjustable flow controller, an adjustable amount of tempering fluid is provided to the exhaust gas prior to the exhaust gas proceeding to the catalyst. A sensor senses a parameter indicative of a temperature of the exhaust gas being introduced to the catalyst. A computer processor uses a relationship to relate the parameter to an adjustment of the adjustable flow controller that will adjust the amount of tempering fluid provided to the exhaust gas and change the temperature of the exhaust gas being introduced to the catalyst toward a target temperature. Adjustment of the adjustable flow controller is initiated by the computer processor to change the flow of the tempering fluid, and the relationship between the parameter and the adjustment of the adjustable flow controller is updated.

Abstract: A mass spectrometer is disclosed wherein an ion signal is split into a first and second signal. The first and second signals are multiplied by different gains and are digitised. Arrival time and intensity pairs are calculated for both digitised signals and the resulting time and intensity pairs are combined to form a high dynamic range spectrum. The spectrum is then combined with other corresponding spectra to form a summed spectrum.

Abstract: A blood glucose meter and computer-implemented method for improving glucose management through modeling of circadian profiles is provided. For each daily meal period, two sets of pre- and post-meal period data are collected into a circadian profile and stored on a glucose meter, including a level of blood glucose of a diabetic patient and a dosage of diabetes medication. A model of predicted blood glucose for the patient is created from the blood glucose levels in each record as expected blood glucose values and predicted errors and visualized in a log-normal distribution. Target ranges for blood glucose at each meal period are determined and superimposed over the expected blood glucose values. Pharmacodynamics of the medication are obtained. An incremental change in dosing of the medication is propagated over a model day and the expected blood glucose values and their predicted errors are adjusted in response to the incremental dosing change.

Abstract: Embodiments of methods of querying a diabetic patient regarding compliance with adherence criteria comprises instructing the diabetic patient to collect at least one sample in a sampling set of biomarker data, wherein each sampling set comprises a sufficient plurality of samples recorded over a collection period, comparing the collected samples to an acceptable range, wherein the acceptable range encompasses biomarker values that would be expected upon compliance with the adherence criteria, and informing the diabetic patient if at least one sample is an unacceptable value which falls outside of the acceptable range, and performing at least one additional task after detecting the unacceptable value.

Abstract: The present invention provides novel techniques for optimizing throughput and yield using model predictive control techniques. In particular, the present techniques are presented in the context of biofuel production, wherein the trade off between yields of biofuel production and overall system throughput may be optimized. However, the present techniques may also be applied to any other suitable applications where a batch process of the system may affect a change in a property of the produced product, such as liquor processing.

Abstract: A method is provided for generating measurement parameters for a particle sample in a particle analyzer. The method includes, interrogating the particle sample with a triggering interrogator and one or more secondary interrogators respectively positioned along a length of an interrogation area, generating respective pulses based upon the interrogation of a first particle from the particle sample, determining a primary pulse detection window based upon a triggering pulse, determining a search interval to find a secondary pulse based upon factors including the primary pulse detection window and a laser delay, adjusting the search interval for laser delay variation dynamically based on the interrogation of the first particle, identifying the secondary pulse in the adjusted search interval, and processing the secondary pulse to determine a peak value of the secondary pulse. Corresponding apparatus are also provided.

Abstract: A population comparison system, method and a computer program product therefor. A stored list of population members, e.g., hydrocarbon reservoirs, characteristics and analogous members is partitioned into lists for each member. A weighting system automatically uses the partitions to determine a weight set (w*) for population member characteristic and a similarity function. The weighting system may include an objective model that iteratively, blindly identifies analogous members for each population member until the identified analogous members match the listed analogous members. An analogous member selector uses the weights set (w*) and similarity function to automatically select analogous listed members for each new population member.

Abstract: A method and apparatus is provided for concentration determination of at least one component in an acid catalyst for hydrocarbon conversion containing an unknown concentration of an acid, an acid-soluble-oil (ASO), and water. An instrument configured for measuring a property of the acid catalyst, has responsivities to concentrations of one of the acid, ASO, and water, substantially independent of the concentrations of the others of the acid catalyst, ASO, and water. A temperature detector is configured to generate temperature data for the acid catalyst. A processor is configured to capture data generated by the temperature detector and the instrument, and to use the data in combination with a model to determine a temperature compensated concentration of the one of the acid, the ASO, and the water. Optionally, one or more other instruments configured for measuring other properties of the liquid mixture may also be used.

Abstract: A method for soil analysis for determining optimal conditions for a soil area and reporting the same. The soil analysis of the present invention combines sound agronomic principles with a unique interpretation of the results to offer a thorough analysis of a property's soil based on the soil sample(s) taken from a particular property. The calculation formulas and variables are consistent for all analyses, with the formulas adjusted based on some specific qualities of the soil.

Abstract: A computer-implemented system and method for improving glucose management through modeling of circadian profiles is provided. Meal period data is assembled, which includes, for each stated period, at least two measurements of pre-meal and post-meal self-measured blood glucose. Diabetes medication dosed over the periods is identified. The assembled meal period data and the medication are organized into a circadian profile for a diabetic patient. A model including expected blood glucose values and their predicted errors at each period is created from the blood glucose measurements and is visualized in a log-normal distribution. Target ranges for blood glucose at each period are determined and superimposed over the expected blood glucose values. Pharmacodynamics of the medication are obtained. An incremental change in dosing of the medication is propagated over a model day and the expected blood glucose values and their predicted errors are adjusted in response to the incremental dosing change.

Abstract: A genealogical research and record keeping system and method for identifying commonalities in haplotypes and other genetic characteristics of a biological sample of two or more individual members. Chromosomal fragments identical by descent identify family ties between siblings, parents and children and ancestors and progeny across many generations. It is particularly useful in corroborating and improving the accuracy of genealogical data and identifying previously unknown genetic relationships.

Abstract: An apparatus for identifying outliers among chemical reaction assays, the apparatus comprising a transition point finder, configured to find at least one transition point in a cumulative function, the cumulative function giving a quantitative indication based on a count of points in a calculated space as a function of distance from a function dividing the calculated space into at least two groups, each one of the points representing results of a respective assay of a chemical reaction. The apparatus further comprises an outlier identifier, in communication with the transition point finder, configured to use a distance of the found transition point from the function dividing the calculated space, as a threshold, for identifying an outlier among the chemical reaction assays.

Abstract: Provided is a novel hydrogen separation membrane formed of a Nb—W—Mo-based alloy. A method for separating hydrogen using the hydrogen separation membrane and hydrogen separation conditions are selected by a particular procedure. A hydrogen separation membrane formed of the Nb—W—Mo-based alloy membrane.

Abstract: The invention provides a system and method for selecting an optimal multimarker reagent combination for the identification and/or quantification of molecules in or on cells with or without reference to fluorescence or other properties of at least one fluorescent dye or other instrument-measurable atom or molecule associated directly or indirectly with the reagent combination. The method includes specifying, using a computer, a plurality of markers to be detected by a plurality of reagents, generating, using a computer, a plurality of reagent combinations comprising the plurality of reagents to detect the plurality of markers, wherein the reagent combinations are ranked according to at least one user-defined or system-defined criterion, and selecting the optimal reagent combination or providing a rank-ordered list of combinations.

Abstract: Disclosed are a method and an apparatus for estimating the features (concentration, weight, volume, etc.) of target materials, by using kinetic change information along time, when measuring the results of a chemical reaction between two materials, target materials and reactant, with an optical or electrochemical method.

Abstract: This invention is to make it possible for the analysis system to conduct the minimum operation of the management device or monitoring a movement of the analysis device continuously while preventing an unexpected operation by an unauthorized user. In order to attain this object, the access level is automatically changed to the smaller operable range in case that the operation conducted based on a certain access level is interrupted for a certain period of time.

Abstract: A testing method for identification whether a cancer patient is a member of a group or class of cancer patients that are not likely to benefit from administration of a platinum-based chemotherapy agent, e.g., cisplatin, carboplatin or analogs thereof, either alone or in combination with other non-platinum chemotherapy agents, e.g., gemcitabine and paclitaxel. This identification can be made in advance of treatment. The method uses a mass spectrometer obtaining a mass spectrum of a blood-based sample from the patient, and a computer operating as a classifier and using a stored training set comprising class-labeled spectra from other cancer patients.

Abstract: Systems and method for detecting optical signals, and for discriminating optical signals emitted by an emission moiety that is excited by an associated excitation signal from background signals and other optical noise, employing digital techniques for determining the portion of a detected optical signal having a modulation frequency corresponding to a modulation of the associated excitation signal.

Abstract: A health-monitoring device assesses the health of a user based on levels of two analytes in a biological fluid. A first analyte that is utilized to assess a user's health is a fat metabolism analyte, such as ketones, free fatty acids and glycerol, which is indicative of fat metabolism. A second analyte that is utilized is a glucose metabolism analyte, such as glucose. The levels of the two analytes may be used to assess insulin sensitivity, to detect both recent hypoglycemia and the cause of high glucose levels, and/or to guide therapeutic intervention.

Abstract: The present invention includes analyte measurement systems, analyte measurement meters, analyte testing devices, cartridges thereof and integrated circuits for use therewith, and further includes methods related to the use of the integrated circuits and, in certain embodiments, to the counting or tracking of parameters related to the cartridges and analyte test devices.

Abstract: The present invention is directed to a processor-based analysis system and method. The technology includes a water analysis computer program, which may be an app for a smart device. Beneficially, an interactive visual display device is in communication with a sensing device. Advantageously, test parameter algorithms may be updated, and use of an auxiliary product with an intended test may be validated. Benefits further include improved accuracy of test results, user customization, and storage, management and output of associated data.

Abstract: A mobile device includes a chemical sensor to detect chemicals in the environment in which the mobile device is present. The detected chemicals are analyzed and used to generate a chemical characteristic of the environment. The chemical characteristic of the environment is used to determine location related data for the mobile device. For example, an implemented within or remote chemical characteristic database that stores chemical characteristics associated with location related data may be searched based on the chemical characteristic of the environment to determine the location of the mobile device. The location related data may be a location of the mobile device or assistance data that may be used to assist in generating a more accurate position fix, e.g., using a satellite positioning system. The location related data may simply whether the mobile device is inside or outside or the floor of a multi-floor building.

Abstract: The present invention provides an apparatus and methods for variably supplying power from a stand-alone fuel cell power supply system including a power conversion unit, a power switching unit and a load control unit. Preferably, a controller manages system configuration to switch the loads, the power conversion and the delivery between the two without reducing capacity by redundantly backing up each individual portion with a bank of at least two modules for each unit. Preferably, controller actuated devices are triggered automatically in response to monitors that sense performance operating parameters and detect values operating outside a threshold range.

Abstract: It is intended to provide a drug delivery system which makes it possible to solve the existing technical problems and is easily usable in practice. A drug, which comprises an organic compound or an inorganic compound and has been magnetized by modifying a side chain and/or crosslinking side chains, is induced by a magnetic force into target tissues or an affected part.

Abstract: A method of classifying plant embryos according to their quality based on a general form of Lorenz-Bayes classifier is disclosed. First, image or spectral data of plant embryos of known quality are acquired, and the data are divided into two classes according to the embryos' known quality. Second, metrics are calculated from the acquired image or spectral data in each class. Third, multi-dimensional histograms of multiple metrics are prepared for both classes. Fourth, the difference or some other measure of comparison between the two multi-dimensional histograms is obtained. Fifth, image or spectral data of a plant embryo of unknown quality are obtained and metrics are calculated therefrom. Sixth, the embryo of unknown quality is assigned to a class based on its calculated metrics and the result of the comparison as calculated in the fourth step above.

Abstract: A sample detection apparatus (200) for detecting a fluidic sample flowing through a first flow cell (202) and flowing through a second flow cell (204) of a sample separation system (10), wherein the first flow cell (202) has a first path length (D) and the second flow cell (204) has a second path length (d) being smaller than the first path length (D), wherein the sample detection apparatus (200) comprises a data determining unit (206) configured for determining first data indicative of a first relation between a detection signal intensity and a concentration of the fluidic sample in the first flow cell (202), and configured for determining second data indicative of a second relation between a detection signal intensity and the concentration of the fluidic sample in the second flow cell (204), and a data combining unit (208) configured for combining the first data and the second data in accordance with a continuous weighting function to thereby derive a weighted relation between detection signal intensity and

Abstract: A mass spectrometry system is mounted with (1) an action planning module for determining a measurement schedule provided by a combination of an MS analysis and an MSn analysis (where n?2) according to a measuring time provided previously; and (2) a mass spectrometry unit having a tandem mass spectrometry function for outputting a mass spectrum obtained by performing each measurement action constructing the measurement schedule.

Abstract: An apparatus that generates brewed beverages by performing one or more chemical and/or mechanical processes may receive requests to produce specified brewed beverages. The apparatus may include a master controller that initiates and controls performance of the chemical and/or mechanical processes to produce the specified beverages. The master controller may adaptively apply one or more process accelerators during the performance of one of the chemical or mechanical processes to accelerate the process or to achieve a desired qualitative or quantitative characteristic for a beverage or a component thereof. The adaptive application of one or more process accelerators may be dependent on a multiple-variable process profile developed for the process and/or a specified beverage. For example, the pressure in a steam wand and/or the depth of the wand may be varied during a process to froth milk in order to produce frothed milk having a desired temperature.

Abstract: An instrument, method, use and software program to obtain information rapidly about microorganisms that may spread uncontrolled in hospitals, water supply, food or when used in bio terrorism are described. Vibrational spectroscopy provides data to a computer linked to one or more databases. Comparison of the spectral data and information retrieved from the databases is used to identify and classify the microorganisms, applying suitable algorithms, which algorithms are self-generating and self-adapting to new spectroscopic data. The system may alert for the detection of an outbreak or to take disinfection measures. Changes in the traditional taxonomic division of microorganisms have no influence on the instrument. It does not rely on an a priori knowledge about the taxonomic classification of the microbial strain, is straightforward and easily integrated in routine microbial procedures.