Instrument Proving Or Calibrating Patents (Class 73/1.01)
  • Patent number: 7318908
    Abstract: Integrated nanotube sensors are adapted for detecting various chemical and biological molecules. In one implementation, nanotube sensor arrays are formed as nano-electronic noses capable of such detection, and can be implemented in devices including carbon nanotube-based electronic noses and biochips. Various implementations of the present invention are also directed to nanoscience and nanotechnology applications, such as medical, military and biological applications. In a more particular implementation, nanotubes are produced on full-scale wafers and functionalized. In another more particular implementation, functionalized nanotubes are integrated into addressable devices. With these approaches, various aspects of the present invention have been found to be useful in sensor applications having small size, high density and extreme sensitivity. Such sensor applications are applicable to many aspects of society, and can be implemented for making human lives more safe, secure and healthy.
    Type: Grant
    Filed: October 31, 2002
    Date of Patent: January 15, 2008
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventor: Hongjie Dai
  • Patent number: 7318907
    Abstract: Methods and apparatus for producing small, bright nanometric light sources from apertures that are smaller than the wavelength of the emitted light. Light is directed at a surface layer of metal onto a light barrier structure that includes one or more apertures each of which directs a small spot of light onto a target. The incident light excites surface plasmons (electron density fluctuations) in the top metal surface layer and this energy couples through the apertures to the opposing surface where it is emitted as light from the apertures or from the rims of the apertures. Means are employed to prevent or severely limit the extent to which surface plasmons are induced on the surface at the aperture exit, thereby constraining the resulting emissions to small target areas.
    Type: Grant
    Filed: August 14, 2002
    Date of Patent: January 15, 2008
    Assignee: President and Fellows of Harvard College
    Inventors: Peter Randolph Hazard Stark, Dale N. Larson
  • Patent number: 7306951
    Abstract: A measuring apparatus and method for use in measuring diffusible hydrogen concentrations in materials, structures, and other objects. In an embodiment of the invention for use in welding applications, the measuring apparatus (10) includes a sensor assembly (20) that, with an included sealing member (40), defines a sample area (17) on a weld bead (16) from which hydrogen evolves into a sample volume (18) defined by the sealing member (40), a sensor housing (34) and a sensor (22) of the sensor assembly (20). The hydrogen reacts with a sensing layer (28) and a reflector layer (30) positioned on the end of an optical fiber (24), all of which are included in the sensor assembly (20) and are sealably positioned within the sensor (22).
    Type: Grant
    Filed: June 8, 2000
    Date of Patent: December 11, 2007
    Assignee: Midwest Research Institute
    Inventors: David K. Benson, Thomas R. Wildeman, R. Davis Smith, David L. Olson
  • Publication number: 20070277587
    Abstract: A sensor apparatus and method include a sensor configured on an integrated circuit, which includes a current limiting open collector output stage configured in association with the integrated circuit. The current limiting open collector output stage reduces a fall time and a di/dt associated with an output signal of the sensor and a ringing produced thereof in order to improve EMC and conducted emissions required of the sensor.
    Type: Application
    Filed: June 2, 2006
    Publication date: December 6, 2007
    Inventors: Steven D. Foster, Jason M. Chilcote, John A. Modica
  • Patent number: 7303727
    Abstract: Methods and apparatus for delivering fluidic materials to sample destinations, including mass spectrometers for analysis are provided. In preferred embodiments, sample aliquots are electrosprayed from tapered spray tips of capillary elements into the orifices of mass spectrometric inlet systems. In certain embodiments, fluidic samples are orthogonally sprayed from capillary elements or other fluid conduits, whereas in other embodiments samples are sprayed after devices are rotated or otherwise translocated from sample sources to sample destinations. In still other embodiments, samples are sprayed from flexed or deflected capillary elements at selected sample destinations.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: December 4, 2007
    Assignee: Caliper Life Sciences, Inc
    Inventors: Robert S. Dubrow, Michael Greenstein, Luc J. Bousse, Khushroo Gandhi
  • Patent number: 7297549
    Abstract: A method of determining bias in a measurement of a constituent concentration level in a sample gas is provided. The method comprises establishing a sample gas flow from an emission stream into a sample gas line of an emissions monitoring system. The method further comprises removing water from the sample gas flow and cooling the sample gas flow to a temperature below about 41° F. to produce a cooled, dried sample gas flow. The constituent concentration level is then determined for the cooled, dried sample gas flow. The method further comprises introducing a span gas having a known span gas constituent concentration level into the sample gas flow to form a combined sample and span gas flow, the span gas being introduced at a desired span gas flow rate. The method still further comprises removing water from the combined sample and span gas and cooling the combined sample and span gas to a temperature below about 41° F. to produce a cooled, dried, combined sample and span gas flow.
    Type: Grant
    Filed: March 6, 2002
    Date of Patent: November 20, 2007
    Assignee: General Electric Company
    Inventors: William Steven Lanier, Glenn England
  • Patent number: 7286942
    Abstract: A system and method of fluctuation enhanced gas-sensing using SAW devices includes processes for improved chemical analyte detection, identification, and quantification through the measurement and spectral analysis of frequency fluctuations in the instantaneous frequency of a chemical sensor arranged to produce an oscillatory output signal when exposed to chemical substances. The system and method may use a chemical sensor, such as a surface acoustic wave (SAW) device. The spectral analysis produces the power spectral density of the frequency fluctuations, which are represented as a pattern that includes information about the analyte(s) such as, total adsorbed gas mass and diffusion coefficients. The diffusion coefficients may then be used to determine the number of molecule types and/or the concentration of each.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: October 23, 2007
    Assignee: United States of America as Represented By The Secretary of the Navy
    Inventors: Laszlo B. Kish, Gabor Schmera
  • Patent number: 7285246
    Abstract: A hand-held device detects the presence of a preselected substance in the breath. A deformable housing forms a test chamber for interacting an indicator reagent with the breath. An ampoule positioned inside the housing is ruptured by manual pressure through the walls of the housing. The contents of the ruptured ampoule are exposed to the breath introduced into the chamber. The presence of a substance in the breath causes the indicator reagent to undergo a visually ascertainable change. The ampoule is secured within the housing by a pair of filter plugs having inboard concavities to receive the rounded ends of the ampoule to center it within the housing, and plural detents prevent slippage of the filters. Additional embodiments lower the user's risk of being cut by glass shards, prevent reagent inhalation, enhance the visual aspects of the device, and physically indicate the presence of breath flowing through the device.
    Type: Grant
    Filed: August 19, 2003
    Date of Patent: October 23, 2007
    Assignee: Akers Acquisition Sub, Inc.
    Inventor: Lawrence Martin
  • Patent number: 7279132
    Abstract: A chemical vapor sensor is provided that measures a chemical species of interest with high sensitivity and chemical specificity. In an aspect, an ethanol vapor sensor is provided, sized for being inconspicuous and on-board a vehicle, having a passive measurement mode and an active breathalyzer mode, for detecting a motor vehicle driver that exceeds a legal limit of blood alcohol concentration (BAC), for use with vehicle safety systems. For the passive mode, a vapor concentrator is utilized to amplify a sampled vapor concentration to a detectible level for use with an infrared (IR) detector. In an aspect, ethanol vapor in a vehicle cabin is passively measured and if a predetermined ethanol level is measured, a countermeasure is invoked to improve safety. In an aspect, an active breathalyzer is used as a countermeasure. The active breathalyzer can be imposed for a number of vehicle trips or for a predetermined time period.
    Type: Grant
    Filed: January 12, 2005
    Date of Patent: October 9, 2007
    Assignee: Delphi Technologies, Inc.
    Inventors: Michel F. Sultan, David K. Lambert
  • Patent number: 7279337
    Abstract: Systems and methods of identifying molecules of polymers such as, for example, a nucleic acid, are described. The method involves centering a bias voltage across a pair of nanoelectrodes separated by a channel that corresponds to one of any of the energy differences between any two internal energy levels of a molecule of interest, and modulating the bias voltage with a modulation waveform while the molecule of interest is in the channel. An electrical signal characteristic of the molecule of interest is derived from the tunneling current between the nanoelectrodes, and the characteristic electrical signal is compared with known values of the signal for chemically-known molecules in order to identify the molecule of interest. Multiple pairs of nano-electrodes may be employed to identify more reliably a single molecule or multiple molecules.
    Type: Grant
    Filed: March 10, 2004
    Date of Patent: October 9, 2007
    Assignee: Agilent Technologies, Inc.
    Inventor: Miao Zhu
  • Publication number: 20070227225
    Abstract: A scanner instrument used for scanning tubing that is being placed into an oil well or being removed from the oil well can be calibrated during retrieval of tubing from the well. Calibrating the tube scanner includes scanning a tubing standard and comparing the data from the standard scan to the known characteristics of the standard. The relationship between the scanned data and the known characteristics can be computed. The relationship between the scanned data and the known characteristics can be used as the calibration function for the scanner. Calibrating the tube scanner can also include scanning a string of tubing segments and then adjusting the data collected. The adjustment is based upon equalizing the data peaks that occur in the scan data at the coupling joints between tube segments.
    Type: Application
    Filed: March 26, 2007
    Publication date: October 4, 2007
    Inventor: Frederic M. Newman
  • Patent number: 7263870
    Abstract: The instrument panel gauge assembly includes an applique having gauge graphics printed thereon and a needle pointer for a gauge assembly positioned adjacent thereto. A transparent chaplet is formed within the applique to allow light to pass through. The needle passes over the chaplet as the needle moves. When the needle is positioned directly in front of the chaplet, light is blocked from passing through the chaplet. A light sensing element is positioned behind the applique to detect the presence of light passing through the chaplet. A light baffle guides light passing through the chaplet to the light sensing element. A controller receives a signal from the light sensing element indicating when the needle pointer is directly in front of the chaplet. The controller then compares the actual input to the gauge with the position of the needle pointer, calculates a correction factor, and calibrates the gauge accordingly.
    Type: Grant
    Filed: August 24, 2005
    Date of Patent: September 4, 2007
    Assignee: Visteon Global Technologies, Inc.
    Inventors: Cesar Avitia, Martin Joel Ibarra, Raul Antonio Rascon
  • Patent number: 7255836
    Abstract: A device and method for quantifying an impurity in an input gas stream. The device and method employ a catalyst to convert the impurity to a detectable species in an output gas stream, and the concentration of the detectable species is then measured by means of a detector.
    Type: Grant
    Filed: March 13, 2003
    Date of Patent: August 14, 2007
    Assignee: Trustees of Princeton University
    Inventors: Kevin Lehmann, Yu Chen, Wen-Bin Yan
  • Patent number: 7250138
    Abstract: A system and method for detecting the presence of submicron sized particles in a sample taken from the environment includes a collecting a sample from the environment and purifying and concentrating the submicron particles in a sample based on the size of the particles. The purified and concentrated particles are detected with an apparatus which includes an electrospray assembly having an electrospray capillary, a differential mobility analyzer which receives the output from the capillary, and a condensation particle device for counting the number of particles that pass through the differential mobility analyzer.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: July 31, 2007
    Assignee: United States of America as respresented by the Secretary of the Army
    Inventor: Charles Harold Wick
  • Publication number: 20070169533
    Abstract: A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.
    Type: Application
    Filed: December 30, 2005
    Publication date: July 26, 2007
    Applicant: Medtronic MiniMed, Inc.
    Inventors: Rajiv Shah, Wayne A. Morgan, David Y. Choy, James L. Henke, Bahar Reghabi, Gopikrishnan Soundararajan, Peter Schultz, Udo Hoss
  • Publication number: 20070173712
    Abstract: A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry cases a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulator voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.
    Type: Application
    Filed: December 30, 2005
    Publication date: July 26, 2007
    Applicant: MEDTRONIC MINIMED, INC.
    Inventors: Rajiv Shah, Bahar Reghabi, James L. Henke, Wayne A. Morgan, Gopikrishnan Soundararajan, David Y. Choy, Peter Schultz, Udo Hoss
  • Patent number: 7247274
    Abstract: The present invention provides novel microfluidic devices and methods for preventing/ameliorating formation of precipitate blockages in microfluidic devices. In particular the devices and methods of the invention utilize microchannels of specific cross-sectional configuration and of specific arrangement as well as application of AC current orthogonal to the direction of fluid flow, in order to preventing/ameliorating formation of precipitate blockages in microfluidic devices.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: July 24, 2007
    Assignee: Caliper Technologies Corp.
    Inventor: Andrea W. Chow
  • Patent number: 7247271
    Abstract: A compact ceramic fuel property sensor comprises a plurality of laminated ceramic layers. The heater, temperature sensor, and capacitance measurement electrodes are embedded between the layers. The capacitance electrodes include interdigitated electrodes and fuel traps for containing a sample of liquid fuel disposed between the interdigitated electrodes. The dimensions of the fuel traps are selected so that the fuel traps remain filled with liquid after said sensor has been bathed in fuel. A method for monolithically preparing the sensors provides a reduced cost method and a sensor that can survive indefinitely in liquid fuel.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: July 24, 2007
    Assignee: Delphi Technologies, Inc.
    Inventors: Da Yu Wang, David K. Lambert
  • Patent number: 7229593
    Abstract: An apparatus for measuring the effective vapor diffusion coefficient of a test vapor diffusing through a sample of porous media contained within a test chamber. A chemical sensor measures the time-varying concentration of vapor that has diffused a known distance through the porous media. A data processor contained within the apparatus compares the measured sensor data with analytical predictions of the response curve based on the transient diffusion equation using Fick's Law, iterating on the choice of an effective vapor diffusion coefficient until the difference between the predicted and measured curves is minimized. Optionally, a purge fluid can forced through the porous media, permitting the apparatus to also measure a gas-phase permeability. The apparatus can be made lightweight, self-powered, and portable for use in the field.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: June 12, 2007
    Assignee: Sandia Corporation
    Inventor: Clifford K. Ho
  • Patent number: 7223607
    Abstract: The invention relates to a process for the detection of hydrocarbons other than methane in a gas predominantly or essentially comprising oxygen, as well as methane and the said hydrocarbons other than methane, the said process comprising: a stage of detection of the combined hydrocarbons in the said gas, providing a first value for the combined hydrocarbons, a stage of combustion of the hydrocarbons other than methane, a stage of detection of methane in the said gas, providing a second value, a stage of calculation of the amount of hydrocarbons other than methane by the difference between the first value and the second value. The invention also relates to a device for implementing this process.
    Type: Grant
    Filed: February 5, 2002
    Date of Patent: May 29, 2007
    Assignee: L'Air Liquide Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges Claude
    Inventor: Francis Bryselbout
  • Patent number: 7221448
    Abstract: The invention relates to a sample cell with a glass body comprising a gas inlet and a gas outlet and at least one orifice, a plane glass window is fused into the orifice, the shape and size of the window corresponds to the shape and size of the orifice, the orifice is limited by a rim, the rim is wider than the thickness of the window, the rim of the window is fused with the rim of the orifice. The invention further relates to a method of producing the sample cell. The window is inserted into the orifice. The rim of the orifice is heated several times from the exterior in such a way that the glass melts and a fused joint is formed between the window and the rim of the orifice. The sample cell produced by the method has a particularly rigid joint between the window and the glass body. Therefore, this glass cell is able to withstand pressures above 10 bar and allows the passage of light without lens effects owing to its plane-parallel windows. The sample cell is used in a polarizer for inert gas.
    Type: Grant
    Filed: June 7, 2000
    Date of Patent: May 22, 2007
    Assignee: Forschungszentrum Julich GmbH
    Inventors: Stephan Appelt, Giovanni D'Orsaneo, Nadim Joni Shah
  • Patent number: 7217393
    Abstract: An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the reflected light beam from the flow cell, thereby monitoring the test.
    Type: Grant
    Filed: May 14, 2004
    Date of Patent: May 15, 2007
    Assignee: Fastraq, Inc.
    Inventors: Thomas R. Witty, Robert Case
  • Patent number: 7213478
    Abstract: A method of automatically configuring an Advanced Process Control (APC) system for a semiconductor manufacturing environment in which an auto-configuration script is generated for executing an auto-configuration program. The auto-configuration script activates default values for input to the auto-configuration program. The auto-configuration script is executed to generate an enabled parameter file output from the auto-configuration program. The enabled parameter file identifies parameters for statistical process control (SPC) chart generation.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: May 8, 2007
    Assignee: Tokyo Electron Limited
    Inventors: Satoshi Harada, Edward C. Hume, III, James E Willis, Kevin Andrew Chamness, Hieu A Lam, Hongyu Yue, David Fatke
  • Patent number: 7211222
    Abstract: A powder filler is stuffed in a filler space defined between a housing and a gas sensing element so as to airtightly seal a clearance between the housing and the gas sensing element. The powder filler contains grains whose diameter is in a range from 80 ?m to 5,000 ?m when measured before being stuffed into the filler space. A weight percentage of the grains having the diameter of 80 ?m to 5,000 ?m is equal to or larger than 80% with respect to an overall weight of the powder filler.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: May 1, 2007
    Assignee: Denso Corporation
    Inventors: Motoaki Satou, Kiyomi Kobayashi, Masanobu Yamauchi, Namitsugu Fujii
  • Patent number: 7204145
    Abstract: An activity monitor is provided that corrects for the effects of motion external to the entity being monitored. For example, the activity monitor can overcome the effects of vehicular travel.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: April 17, 2007
    Assignee: Koninklijke Philips Electronics, N.V.
    Inventors: Carsten Heinks, Peter Tjin Sjoe Kong Tsang
  • Patent number: 7201877
    Abstract: A device for detecting sulfuryl fluoride, in which the gas specimen to be examined is subjected to pyrolysis with ensuing detection of a pyrolysis product, is to be improved for the sake of achieving a mobile, economical structure. To attain this object, in a preliminary tube (1) for pyrolysis, there is a chemical layer (5) of pyrophoric iron, and as an indicator system for the pyrolysis product, a test tube (2) for hydrogen fluoride is used.
    Type: Grant
    Filed: September 25, 2003
    Date of Patent: April 10, 2007
    Assignee: Dräger Safety AG & Co. KGaA
    Inventors: Holger Bohm, Silke Guga, Andreas Mohrmann, Armin Schulten, Bernd Siemensmeyer, Katja Stern, Bettina Runge
  • Patent number: 7197949
    Abstract: A sampling system for detecting an analyte, comprising a diaphragm pump, a buffer chamber, a sensor head and intake port. The pump includes a chamber for receiving fluids via first and second ports. A buffer chamber is located at the second port for holding a quantity of air, and a sensor head is adapted to identify the presence of a desired analyte and produce a signal in response to the quantity identified. Preferably the diaphragm pump has a volume of gas per stroke capacity slightly larger than the volume of the sensor head such that the pump chamber has a greater volume than the buffer chamber and the buffer chamber has about the same volume as the sensor head. A sensor intake port intakes a sample potentially containing the analyte for contact with the sensor head upon operation of the diaphragm pump and out of the sensor head by jet-action caused by rapid movement of the diaphragm pump. A filter may be used for filtering air drawn through the pump chamber.
    Type: Grant
    Filed: April 2, 2002
    Date of Patent: April 3, 2007
    Assignee: Honeywell International Inc.
    Inventors: J. David Zook, Cleopatra Cabuz
  • Patent number: 7200495
    Abstract: Devices and techniques for estimating the concentration of one or more agents in a fluid environment employ a plurality of measurements of a sensor attribute that changes in response to an agent. Measurements taken before the agent/reagent combination reaches a steady-state may be used. The plurality of measurements are processed using a nonlinear, parametric model of the interaction between the sensor and the agent to determine the concentration of the agent. The model takes into account the finite capacity of a sensor reagent. The model characterizes the interaction of individual agent/reagent combinations with a set of parameters. These parameters require minimal testing to calculate. The invention enables the response of a sensor to an agent over the entire range of agent concentration levels to be efficiently and accurately characterized. The invention also enables the prediction of collective responses given parameters characterizing a plurality of agent/reagent combinations.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: April 3, 2007
    Assignee: The Charles Stark Draper Laboratory
    Inventor: Mukund N. Desai
  • Patent number: 7192777
    Abstract: An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the reflected light beam from the flow cell, thereby monitoring the test process. The apparatus may have additional light source so that the photo sensor may monitor the test process by detecting the absorption light beam or fluorescent light beam from the flow cell at different phases of the test process.
    Type: Grant
    Filed: April 5, 2005
    Date of Patent: March 20, 2007
    Assignee: Fastraq, Inc.
    Inventors: Thomas R. Witty, Robert Case
  • Patent number: 7189360
    Abstract: A circular chemiresistor for use in microchemical sensors. A pair of electrodes is fabricated on an electrically insulating substrate. The pattern of electrodes is arranged in a circle-filling geometry, such as a concentric, dual-track spiral design, or a circular interdigitated design. A drop of a chemically sensitive polymer (i.e., chemiresistive ink) is deposited on the insulating substrate on the electrodes, which spreads out into a thin, circular disk contacting the pair of electrodes. This circularly-shaped electrode geometry maximizes the contact area between the pair of electrodes and the polymer deposit, which provides a lower and more stable baseline resistance than with linear-trace designs. The circularly-shaped electrode pattern also serves to minimize batch-to-batch variations in the baseline resistance due to non-uniform distributions of conductive particles in the chemiresistive polymer film.
    Type: Grant
    Filed: January 23, 2003
    Date of Patent: March 13, 2007
    Assignee: Sandia Corporation
    Inventor: Clifford K. Ho
  • Patent number: 7189354
    Abstract: An enclosed chamber is used in a system for screening of a liquid specimen through binding assays. The enclosed chamber includes an inlet, an outlet, and a plurality of discrete reactant containing wells communicated by a common reagent flow path between the inlet and the outlet. A transparent member or coverslip defines on an inside thereof the plurality of wells. Each well has a bottom for receiving an allergent/antigen/reactant, which emits light upon reacting. The coverslip can optionally define at least one lens at each well. A bottom encloses the plurality of wells and defines between the inlet and the outlet a common reagent flow path between the inlet and the outlet. This bottom defines for each of the plurality of wells a flow-diverting member. An opaque partition is disclosed for surrounding the individual lenses and generally isolating the light path from each well.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: March 13, 2007
    Assignee: Hitachi Chemical Diagnostics, Inc.
    Inventors: Dianna Innerst, Adonis Kassinos, C. Benjamin Wooley, Brett Wilmarth, William J. Sell, Emi Zychlinsky, Donald Marino, Sandy Yamada, Renee Ryan, Karen Ding, Michael Zatzke
  • Patent number: 7189315
    Abstract: An ion sensor has a flow path through which a sample flows. An ion-exchange membrane is in contact with the sample in the sample flow path. An internal solution is provided on one side of the ion-exchange membrane. An internal electrode is provided so as to come in contact with the internal solution. The surface of the ion-exchange membrane that does not come in contact with the sample is coated with a two-liquid-mixed epoxy resin.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: March 13, 2007
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Kotaro Yamashita, Koichi Tayama, Noriko Yoshioka, Yasuhisa Shibata
  • Patent number: 7189592
    Abstract: A robust single-chip hydrogen sensor and a method for fabricating such a sensor. By utilizing an interconnect metallization material that is the same or similar to the material used to sense hydrogen, or that is capable of withstanding an etchant used to pattern a hydrogen sensing portion, device yields are improved over prior techniques.
    Type: Grant
    Filed: May 3, 2004
    Date of Patent: March 13, 2007
    Assignee: Honeywell International Inc.
    Inventor: James M. O'Connor
  • Patent number: 7189353
    Abstract: Methods, systems and sensor arrays are provided implementing techniques for detecting an analyte in a fluid. The techniques include providing a sensor array including at least a first sensor and a second sensor in an arrangement having a defined fluid flow path, exposing the sensor array to a fluid including an analyte by introducing the fluid along the fluid flow path, measuring a response for the first sensor and the second sensor, and detecting the presence of the analyte in the fluid based on a spatio-temporal difference between the responses for the first and second sensors.
    Type: Grant
    Filed: February 8, 2005
    Date of Patent: March 13, 2007
    Assignee: The California Institute of Technology
    Inventors: Nathan S. Lewis, Michael S. Freund, Shawn M. Briglin
  • Patent number: 7189363
    Abstract: Of a gas detector 100, a chamber 105 formed between a center cover 150 and a cover 160 is a part of an air flow channel AF. A first shielding plate 165 is provided in the chamber 105. Water droplets that have entered the chamber from a chamber entrance 103 with air hit and adhere to an entrance-opposed surface 165E of the first shielding plate 165. The water thus adhering to the surface is pushed by the air flowing along the entrance-opposed surface 165E and by gravity, to thereby advance downward. The water then drips downward and is accumulated on a bottom wall surface 105WD which serves as an upper surface of a bottom wall section 161WD. The water is pushed by the flow of air, to thereby advance toward a chamber exit 104. The water is then drained downward from the chamber exit 104.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: March 13, 2007
    Assignee: NGK Spark Plug Co., Ltd.
    Inventors: Norimasa Osawa, Kazuto Hirai, Yuichi Koyama
  • Patent number: 7189575
    Abstract: Disclosed is a method for determining the swellability and the swelling kinetics of superabsorbent material (9) such as polymer gels, for example, which comprises introducing a defined volume of the dry superabsorbent material (9) into a measuring vessel (7), using a movable element (4) within said measuring vessel (7) to apply a restraining force (12) to said superabsorbent material (9) and capturing the expansion of said superabsorbent material (9) contactlessly within a chamber (14) in a continuous manner by capturing the change in height of a piston (4) which bounds said chamber (14), travels in a measuring vessel (7) and is marked with a height scale (6).
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: March 13, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Wolfgang Schrof, Udo Gödert, Martin Beck, Hans-Joachim Hähnle, Gunnar Schornick
  • Patent number: 7189358
    Abstract: An integrated micropump or a plurality of integrated micropumps are communicated to a plurality of analysis chambers. A plurality of integrated analysis chambers include integrated analysis devices to test a fluid for an analyte. The micropumps continuously or periodically pump the fluid into the analysis chambers and flush the analysis chambers after analysis of the analyte. In one embodiment, the analysis device comprises an integrated LED and an integrated optical detector. The LED and detector are tuned to an optical absorption line of the analyte. The micropumps are composed of nitrides of B, Al, Ga, In, Tl or combinations thereof and fabricated using photoelectrochemical techniques. The analysis chambers, and micropumps including the analysis devices are simultaneously fabricated during which fabrication of the micropumps and the analysis devices are masked from the photoelectrochemical techniques.
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: March 13, 2007
    Assignee: California Institute of Technology
    Inventors: Robert A. Beach, Robert P. Strittmatter, Thomas C. McGill
  • Patent number: 7189573
    Abstract: An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the reflected light beam from the flow cell, thereby monitoring the test.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: March 13, 2007
    Assignee: FastTraQ, Inc.
    Inventors: Thomas R. Witty, Robert Case
  • Patent number: 7189370
    Abstract: An apparatus integrates one dimensional separation to another dimensional separation and automates the operation of the two dimensional separation. The first dimensional separation is performed in one column while the second dimensional separation is performed in multiple separation columns. The integration is achieved using a one-piece, a two-piece, or a three-piece interface.
    Type: Grant
    Filed: February 21, 2003
    Date of Patent: March 13, 2007
    Assignee: Microchem Solutions
    Inventor: Shaorong Liu
  • Patent number: 7191037
    Abstract: A method for controlling production process by performing near-infrared absorptiometric analysis by simple procedures in an accurate manner, in which control of production process step can be realized at a high accuracy by simple operation based on the thereby obtained analytical results, the said method comprising taking each absorbance spectrum for a plurality of standard samples in an analysis range including near-infrared region, calculating the average intensity and standard deviations for each of selected wave lengths to construct a data base, taking an absorbance spectrum in the said analysis range for each of analysis samples and comparing it with the data base in order to judge whether or not the intensity of the absorbance spectrum is within an assumed tolerance limit determined based on the stored standard deviations of the standard samples in the data base to thereby obtain control data by comparing, when wave lengths at which the observed intensity is outside the tolerance limit are present, thes
    Type: Grant
    Filed: August 6, 2001
    Date of Patent: March 13, 2007
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Toshiharu Mitani, Masami Tsuruoka, Yasuo Miyoshi
  • Patent number: 7189579
    Abstract: A method and device for measuring release rates of contaminants in at least one of a fast release mode and a slow release mode in which a volatile liquid sample is introduced into a sealed transparent reactor vessel having at least one sorbent contained within the transparent reactor vessel and a separator for preventing direct contact between the at least one adsorbent and the at least one volatile liquid sample in the transparent reactor vessel, whereby substantially zero headspace is maintained within the transparent reactor vessel. At least one solvent soluble constituent present in the at least one volatile liquid sample is passed through the separator, resulting in sorption of the at least one solvent soluble constituent by the at least one sorbent. In accordance with one preferred embodiment, the separator is a dialysis bag contained in the transparent reactor vessel into which the resin is placed.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: March 13, 2007
    Assignee: Gas Technology Institute
    Inventors: Bhupendra K. Soni, Thomas D. Hayes
  • Patent number: 7189361
    Abstract: An analytical cell including a lightguide with a plurality of conduits filled with a migration medium. The medium, the lightguide and a surrounding medium have refractive indices selected such that light entering the lightguide is internally reflected within the lightguide to provide substantially uniform illumination of the conduits.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: March 13, 2007
    Assignees: 3M Innovative Properties Company, Applera Corporation
    Inventors: Larry J. Carson, Joel R. Dufresne, Patrick R. Fleming, Michael C. Lea, Nicholas A. Lee, John Shigeura
  • Patent number: 7189364
    Abstract: A hydrogen sensor includes a first electrode 3 and a second electrode 4 provided in contact with a proton conduction layer 2; a gas diffusion controlling portion 6 provided between a measurement gas atmosphere and the first electrode 3; and a support element (1a, 1b) for supporting the proton conduction layer 6, the first electrode 3, the second electrode 4, and the gas diffusion controlling portion 6. Hydrogen contained in a measurement gas introduced via the gas diffusion controlling portion 6 is dissociated, decomposed, or reacted by applying a voltage between the first electrode 3 and the second electrode 4 to thereby generate protons. Hydrogen concentration is obtained on the basis of a limiting current generated as a result of the generated protons being pumped out via the proton conduction layer 2 from the first electrode 3 side of the proton conduction layer to the second electrode 4 side of the proton conduction layer.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: March 13, 2007
    Assignee: NGK Spark Plug Co., Ltd.
    Inventors: Norihiko Nadanami, Tomonori Kondo, Masaya Watanabe, Ryuji Inoue, Noboru Ishida, Takafumi Oshima
  • Patent number: 7186382
    Abstract: A system and method for providing an improved microchip measurement apparatus comprising an external reservoir connected via an input line and output line to a well disposed on the microchip. The reservoir and well may be sealed and a pump connected to the input line so as to enable a continuous flow of liquid from the reservoir to the well. In addition, the volume of liquid in the well may be kept constant, thereby improving the overall measurement accuracy.
    Type: Grant
    Filed: April 12, 2002
    Date of Patent: March 6, 2007
    Assignee: Agilent Technologies, Inc.
    Inventors: Walter Schrenk, Tobias Preckel
  • Patent number: 7186381
    Abstract: A hydrogen gas sensor and/or switch fabricated from arrays nanowires composed of metal or metal alloys that have stable metal hydride phases. The sensor and/or switch response times make it quite suitable for measuring the concentration of hydrogen in a flowing gas stream. The sensor and/or switch preferably operates by measuring the resistance of several metal nanowires arrayed in parallel in the presence of hydrogen gas. The nanowires preferably comprise gaps or break junctions that can function as a switch that closes in the presence of hydrogen gas.
    Type: Grant
    Filed: May 30, 2002
    Date of Patent: March 6, 2007
    Assignee: Regents of the University of California
    Inventors: Reginald Mark Penner, Erich C. Walter, Fred Favier
  • Patent number: 7186379
    Abstract: This invention provides a method and system capable of the continuous, real-time measurement of low concentrations of aqueous free cyanide (CN) using an on-line, flow through system. The system is based on the selective reactivity of cyanide anions and the characteristically nonreactive nature of metallic gold films, wherein this selective reactivity is exploited as an indirect measurement for aqueous cyanide. In the present invention the dissolution of gold, due to the solubilization reaction with the analyte cyanide anion, is monitored using a piezoelectric microbalance contained within a flow cell.
    Type: Grant
    Filed: February 7, 2002
    Date of Patent: March 6, 2007
    Assignee: Battelle Energy Alliance, LLC
    Inventors: Jeffrey J. Rosentreter, Kevin L. Gering
  • Patent number: 7184910
    Abstract: A method of compensating sensor data and a method of evaluating an interlock of an interlock system, in which an allowable variation between sensors varying depending on a driving time for a set of equipment, an RF time, the number of wafers, etc. is minimized, thereby enhancing detection reliability of a defective wafer.
    Type: Grant
    Filed: August 4, 2005
    Date of Patent: February 27, 2007
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Seung-jun Lee, Hak-yong Kim, Yoo-seok Jang, Chang-hun Park, Seung-Yong Doh
  • Patent number: 7179421
    Abstract: A multi-pin chemiresistor for use in microchemical sensors. A pair of free-standing, bare wires is supported by an electrically insulating support, and are oriented parallel to each other and spaced closely together. A free-standing film of a chemically sensitive polymer that swells when exposed to vapors of a volatile chemical is formed in-between the pair of closely-spaced wires by capillary action. Similar in construction to a thermocouple, this “chemicouple” is relatively inexpensive and easy to fabricate by dipping the pair of bare wires into a bath of well-mixed chemiresistor ink. Also, a chemiresistor “stick” is formed by dipping an electrically insulating rod with two or more linear or spiral-wrapped electrical traces into the bath of well-mixed chemiresistor ink, which deposits a uniform coating of the chemically sensitive polymer on the rod and the electrical traces. These “sticks” can be easily removed and replaced from a multi-chemiresistor plug.
    Type: Grant
    Filed: January 23, 2003
    Date of Patent: February 20, 2007
    Assignee: Sandia Corporation
    Inventor: Clifford K. Ho
  • Patent number: 7178386
    Abstract: A parallel fluid processing system including multiple fluid process regions containing solid material in fluid communication with a common first fluid source may be used to conduct analyses and/or synthesis in parallel. A parallel fluid processing data correction method includes supplying and processing a calibrant in each fluid process region, measuring a first physical parameter and deriving at least one correction factor based on the parameter, supplying and processing at least one second fluid in each fluid process region, and then applying the correction factor to yield corrected process data. Retention time correction, peak area correction, and other useful data corrections may be performed. Parallel fluid processing may be performed with microfluidic devices and systems. A system for correcting retention times in parallel liquid chromatography is further provided.
    Type: Grant
    Filed: April 9, 2004
    Date of Patent: February 20, 2007
    Assignee: Nanostream, Inc.
    Inventors: Ronald C. Gamble, Sergey I. Osechinskiy
  • Patent number: 7172730
    Abstract: A thermal sensor has a substrate defining a reaction chamber. The reaction chamber has an inlet for conducting sample into the reaction chamber, a reaction surface and an orifice adjacent the reaction surface defining an outlet from the reaction chamber. The reaction surface is coated with a sorbant for binding agents in the sample. A heat transducer in the substrate and in proximity to the reaction surface is configured for heating the reaction surface.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: February 6, 2007
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventor: Steven E. Carpenter