Abstract: The present subject matter relates to in vivo volumetric bidirectional blood flow imaging using single-pass flow imaging spectral domain optical coherence tomography. This technique uses a modified Hilbert transform algorithm to separate moving and non-moving scatterers within a depth. The resulting reconstructed image maps the components of moving scatterers flowing into and out of the imaging axis onto opposite image halfplanes, enabling volumetric bidirectional flow mapping without manual segmentation.

Abstract: An intraocular lens, and a system and method of providing an intraocular lens, having at least one characteristic of the intraocular lens customized in accordance with a modified regression that includes a modification for corneal spherical aberration. The lens, system and method may indicate measuring at least one biometric parameter of an eye at a desired light level, determining a desired postoperative condition of the eye, obtaining a corneal spherical aberration of the eye, applying at least one empirically derived regression calculation, and predictively estimating, in accordance with an output of the at least one empirically derived regression calculation, the at least one characteristic of the intraocular lens to obtain the desired postoperative condition.

Abstract: An apparatus including an illumination unit for illuminating an eye to be inspected with light from an observation light source or light from a photographing light source; an photographing unit for guiding reflected light from the eye to an photographing element, to record an image thereof; a calculation unit for calculating an appropriate observation or photographing light intensity based on an illumination light intensity of the illumination unit and an image signal of the photographing element; an automatic light intensity adjustment unit for causing one of the observation and photographing light sources to emit light at the calculated light intensity; and a control unit for controlling the adjustment unit according to a selected one of a mode of acquiring the fundus image and a mode of acquiring the anterior ocular image.

Abstract: Disclosed are an illumination device for an observation device comprising one, two or more observation beam paths with one respective beam of observation rays, especially for an ophthalmologic surgical microscope, and a corresponding observation device. Said illumination device is provided with at least one light source for generating at least one beam of observation rays in order to illuminate an object that is to be observed. According to one embodiment of the invention, at least two partial bundles of illumination rays are provided, each of which extends coaxial to a corresponding beam of observation rays, while the partial beams of illumination rays are embodied so as to form two or several illumination spots on the fundus of an object that is to be observed, e.g.

Abstract: The lens geometry and power of an intraocular lens is optimized to provide both distance and near vision correction for a patient. The optimization may be based on one or more measured accommodation-related parameters and one or more estimated accommodation-related parameters. An accommodative amplitude may be predicted based on the measured and estimated accommodation-related parameters, and the optimized the intraocular lens geometry and power established based thereon.

Abstract: An ophthalmologic apparatus includes a projection unit configured to project a light flux to a subject's eye, an imaging optical system configured to form an image of the light flux reflected by the subject's eye or an image of the subject's eye on an imaging plane, an imaging unit provided on the imaging plane of the imaging optical system, a determination unit configured to determine a parameter regarding the imaging unit or the projection unit for acquiring unique information of the subject's eye based on a physical property of the subject's eye, and an acquisition unit configured to acquire the unique information based on the image of the light flux or the image of the subject's eye captured by the imaging unit with use of the determined parameter.

Abstract: An apparatus for performing multiple procedures involving the eye. The apparatus includes a data collection apparatus and a data analysis module. The data collection apparatus for collecting a data set corresponding to at least a portion of an eye of a patient is configured to provide data indicative of at least two neurological disorders selected from the group consisting of glaucoma, macular degeneration, diabetic retinopathy, Parkinson's disease, Alzheimer's disease, dyslexia, multiple sclerosis, optic neuritis, LDS, head trauma, diabetes, and inappropriate responses to contrast sensitivity patterns. The data analysis module interrelates the data indicative of at least two neurological disorders to provide an interpretive result.

Abstract: An eye refractive power measurement apparatus includes: a measuring optical system for projecting measurement light onto a fundus of an examinee's eye, and causing a two-dimensional imaging device to capture the measurement light to be reflected from the fundus as a plurality of target pattern images at different distances from a measurement optical axis; a light deflecting member arranged at a position out of a conjugate position with a pupil of the examinee's eye on an optical path of the measuring optical system; a rotor for rotating the light deflecting member about an optical axis of the measuring optical system to allow a plurality of pattern light beams to be eccentrically rotated on the pupil; and a calculator for measuring an eye refractive power of the examinee's eye based on a target pattern image to be captured by the two-dimensional imaging device.

Abstract: A viewing verification system is disclosed that allows a user to view an image by providing a viewer for the image, determining the space bounded by the foveal-vision of the user, verifying whether substantially the entire meaningful portion of the image has been correlated to the space bounded by the foveal vision of the user.

Abstract: An information processing apparatus includes a determination unit configured to determine an incident angle of a signal light beam made incident on an object to be imaged in accordance with a structure of the object to be imaged and an instruction unit configured to send an instruction to capture a tomographic image of the object to be imaged on the basis of the signal light beam made incident on the object to be imaged at the determined incident angle.

Abstract: An optical apparatus includes a system of optical components capable of operating in a scanning laser ophthalmoscope (SLO) mode and an optical coherence tomography (OCT) mode. The system of optical components includes a first optical module for the SLO mode, a second optical module for the OCT mode, and a first scanning device. The first optical module for the SLO mode includes a first source adapted to provide a first imaging beam for the SLO mode and a first detection device configured to receive a first signal associated with a first image of a retina of an eye. The second optical module for the OCT mode includes a second source adapted to provide a second imaging beam for the OCT mode and a second detection device configured to receive a second signal associated with a second image of the retina.

Abstract: A macular health measurement and storage system comprises a plurality of macular-pigment measurement machine for measuring macular pigment density in humans, a plurality of computers each of which is associated with a corresponding one the macular-pigment measuring machines, and a central host. The plurality of macular-pigment measurement machines include a device for receiving macular pigment data from a patient, at least one data transfer port, and at least one processor that enables the transfer of the macular pigment data from the transfer port. The plurality of computers include a first port coupled to the data transfer port of the corresponding macular-pigment measurement machine for receiving the macular pigment data. Each of the computers includes a second port for transferring patient data. The central host is coupled to the second ports on each of the plurality of computers. The central host includes a storage device for storing the patient data.

Abstract: Embodiments of the present disclosure includes optical tomographic methods and systems for acquiring information based on an image precisely in a short time. In one example, an optical tomographic imaging device may irradiate light on an eye which is the object to be measured via an interferometer 13 using a wavelength scanning-type laser light source 11, and acquire a cross-sectional image. The optical tomographic imaging device may include an object lens 23 at the focus position of the two-axis tilt mirror 22. It may deflect light in the x-axis and y-axis direction using the two-axis tilt mirror 22 and obtain a three-dimensional cross-sectional image without having distortion in the optical axis direction.

Abstract: A non-contact type tonometer includes: a measurement unit including a first measuring unit for measuring an eye pressure of an examinee's eye in a non-contact manner and a second measuring unit for measuring a corneal thickness of the examinee's eye in a non-contact manner; a moving mechanism for causing relative movement of the measurement unit with respect to the examinee's eye; a drive controller for driving the moving mechanism for aligning the measurement unit; and a setting switch controller for switching an alignment reference on the cornea used for aligning the measurement unit between first and second alignment references. The first alignment reference is a reference for measuring the eye pressure with the first measuring unit and the second alignment reference is a reference for measuring the corneal thickness with the second measuring unit and set closer to a corneal rear surface than the first alignment reference.

Abstract: An eye simulation system for testing wavefront sensor systems, the eye stimulation system comprising a housing having a chamber with an opening for allowing light to enter said chamber, a fluid located in the chamber, said fluid having a known index of refraction, a lens positioned relative to said housing such that light entering the opening of the chamber passes through said lens, and a rotatable imaging surface positioned in said chamber such that light passing through said lens propagates through said fluid and is incident on said rotatable imaging surface.

Abstract: An ophthalmic imaging apparatus for imaging a subject's eye includes a detection unit configured to detect facts that the subject's eye moves by an amount of movement thereof, which is equal to or more than a predetermined value, and that the movement thereof is finished, and an imaging start unit configured to start imaging of the subject's eye according to a result of detection by the detection unit.

Abstract: A spectral interferometry apparatus and method are disclosed, that can be used to monitor or measure an unknown length by following a characteristic of an indicating signal. The measurement is performed by adjusting an optical path difference (OPD) in an interferometer part of an interferometer configuration until sound or light or both are obtained with the desired strength and pitch. Embodiments are presented where the unknown length is the eye length. Spectral interrogation of the interferometer optical output is achieved by reading the signal of an analogue photodetector array in a spectrometer or by tuning a swept source and processing the signal of a photodetector. Sound of different pitches are produced either directly in this process, or by using a nonlinear amplifier, or a mixer. For enhanced signal, the array may be driven by a nonlinear clock or the swept source may be driven by a distorted driving signal.

Abstract: Techniques are disclosed in which a topographic parameter is determined in each semi-meridian of the eye by considering the topography in each of three concentric zones from the central axis at 3 mm, 5 mm, and 7 mm and assigning weighting factors for each zone, By selectively treating the weighted values in the three zones, parameters of magnitude and meridian can be obtained for each semi-meridian. From these parameters, a single topographic value for the entire eye (CorT) can be found as well as a value representing topographic disparity (TD) between the two semi-meridians. The topography values for the semi-meridians are used in a vector planning system to obtain treatment parameters in a single step operation.

Abstract: Example embodiments of a large dynamic range sequential wavefront sensor for vision correction or assessment procedures are disclosed. An example embodiment optically relays a wavefront from an eye pupil or corneal plane to a wavefront sampling plane in such a manner that somewhere in the relaying process, the wavefront beam from the eye within a large eye diopter range is made to reside within a desired physical dimension over a certain axial distance range in a wavefront image space and/or a Fourier transform space. As a result, a wavefront beam shifting device can be disposed there to fully intercept and hence shift the whole beam to transversely shift the relayed wavefront.

Abstract: A method of determining an ophthalmic prescription (Rx) for a patient's eye, includes obtaining a wavefront measurement of the patient's eye; determining a first Rx for the patient's eye from the wavefront measurement, the first Rx corresponding to a maximum value of a merit function calculated from the wavefront measurement of the patient's eye for a first size of the pupil of the patient's eye; determining one or more additional Rx's of the patient's eye for one or more additional pupil sizes different from the first pupil size, wherein each additional Rx is determined for a corresponding size by calculating a value of the merit function for the previously-calculated Rx at the corresponding size and searching for an Rx at the corresponding size that provides a larger value of the merit function than the previously-calculated Rx at the corresponding size; determining a final Rx based on the first Rx and the additional Rx's; and outputting the final Rx.

Abstract: A method determines an optical property (S, C) of a patient eye with an intraocular lens. The patient eye and the intraocular lens define a system. In the method, a measured value of the optical property of the system is determined at a measurement time (tM) after injecting the intraocular lens into the patient eye. The measured value and the associated measurement time (tM) are compared to a known time profile of the values of the optical property for the lens. The known time profile since unfolding the intraocular lens was determined experimentally before the lens is injected and is made available in the form of measurement series or data derived therefrom. A value for the optical property of the system is determined at a different time than the measurement time (tM), according to the known time profile of the values of the optical property for the lens.

Abstract: An object of one aspect of the present invention is to obtain a measurement value in accordance with the condition of a crystalline lens of an examinee's eye. An apparatus for measuring ocular axial length includes: a measuring unit which irradiates measurement waves toward a fundus of the examinee's eye, and calculates the ocular axial length of the examinee's eye based on detection signals obtained from reflected waves including waves reflected from the fundus; and a determining unit which acquires reflection information related to an anterior segment of the examinee's eye, extracts reflection signals corresponding to a reflection object between a cornea and a posterior capsule of a crystalline lens based on the acquired reflection information, and determines whether the examinee's eye is a phakic eye or an IOL eye based on the extracted reflection signals.

Abstract: The ophthalmic photographing apparatus includes an optical scanner for two-dimensionally scanning light and an optical coherence tomography device for obtaining a three-dimensional tomographic image of an examiner's eye. The apparatus also includes an observation optical system for obtaining a front observation image of the eye as a moving image and an observation optical system that obtain a front observation image of the examinee's eye as a moving image. The driving control unit controls the optical coherence tomography device based on a signal from an operation unit. A position on the examinee's eye where the tomographic image is picked up is changeable by using the moving image of the front observation image and the analysis map.

Abstract: A binocular viewer, a method of measuring and training vision that uses a binocular viewer and a vision measurement and training system that employs a computer to control the binocular viewer. In one embodiment, the binocular viewer has left and right display elements and comprises: (1) a variable focal depth optical subsystem located in an optical path between the display elements and a user when the user uses the binocular viewer and (2) a control input coupled to the left and right display elements and the variable focal depth optical subsystem and configured to receive control signals operable to place images on the left and right display elements and vary a focal depth of the variable focal depth optical subsystem. In another embodiment, the binocular viewer lacks the variable focal depth optical subsystem, but the images include at least one feature unique to one of the left and right display elements.

Abstract: An ophthalmic photographing apparatus includes: an interference optical system having a light source, a splitter for splitting light from the light source into measurement light traveling toward an examinee's eye and reference light, and an optical detector for receiving combined light of the measurement light reflected by the examinee's eye and the reference light; an optical scanner arranged in an optical path of the measurement light to scan a photographing region of the examinee's eye with the measurement light; a controller for obtaining a tomographic image of the photographing region by controlling the optical scanner and processing an output signal from the optical detector; and an image processor for obtaining a combined tomographic image by combining a plurality of tomographic images corresponding to a plurality of different incident angles.

Abstract: The OculoKinetic Device is used to test an individual to evaluate brain functions and to identify the presence of a traumatic brain injury or disease which manifests itself through abnormal ocular responses to stimuli by using the high-speed tracking of an individual's eye movements, pupil size and reactivity, eye lid position and blink parameters and optionally along with other ocular elements, i.e., eyeball pressure, temperature, blood flow, etc. The eye movement stimulus protocol uses a target that moves in any direction of the two-dimensional plane and may use a color display or geometric shapes. In addition, the stimuli can be used in conjunction with cognitive testing, balance assessment, and other non-eye tests.

Abstract: A wavefront sensor includes a wavefront scanning module configured to output wavefront tilt measurements of a wavefront beam returned from a subject eye, a biometric/anatomic measurement device configured to output biometric/anatomic measurements of the subject eye and a processing system, coupled to the scanning module and the biometric/anatomic measurement device, configured to process biometric/anatomic measurements output during a surgical procedure to determine eye status information and to concurrently output eye status information and wavefront tilt information during the surgical procedure.

Abstract: An ophthalmic illuminator includes a one or more light combining stages arranged in series to augment a white light source with various color spectral bands. A first stage combines white light from a white light source with colored light from a first color source. Each subsequent stage in the series adds its own respective colored light. The color sources may be selectively turned on/off or driven with variable amounts of power. In this fashion, a combined light is produced by the final stage that represents a desired chromaticity and brightness as desired for a particular ophthalmic therapeutic procedure.

Abstract: Treatment table verification techniques involve comparing intended refraction information with expected optical refraction information, and validating or qualifying the treatment table based on such comparisons. Systems and methods for verifying treatment tables provide enhanced safety for laser vision correction treatments.

Abstract: A fundus oculi observing device 1 specifies a characteristic site of a fundus oculi Ef depicted in tomographic images of the fundus oculi Ef and, based on the position of the characteristic site within frames FH and FV of the tomographic images, changes a target position of a signal light LS so that the characteristic site is depicted in the center positions within the frames FH and FV and executes a main measurement, thereby forming a tomographic image and/or a three-dimensional image of the fundus oculi Ef.

Abstract: Provided are systems and methods to temporarily alter visual acuity of a subject. An example system includes a first light source configured to produce infrared light in an infrared wavelength spectrum for transient propagation into an eye of the subject and a second light source configured to produce visible light in a visible wavelength spectrum for transient propagation into the eye of the subject. The system further includes a transmission unit configured to propagate the infrared light and the visible light into the eye, wherein the light propagated into the eye temporarily alters visual acuity of the subject.

Abstract: Embodiments provide methods and systems for the modeling and analysis of visual fields. Methods for global and regional measurement of visual sensitivity and quantification of field loss are provided in accordance with various embodiments. Further embodiments provide systems and methods for the diagnosis of diseases affecting the visual field. In addition, embodiments provide methods and systems for measuring and quantifying the volume of the Hill of Vision for an individual subject.

Abstract: Provided are an optical tomographic imaging apparatus and an imaging method for an optical tomographic image, in which high measurement sensitivity and high lateral resolution of a specific portion of an object may be obtained with a simple structure. The optical tomographic imaging apparatus of a Fourier-domain method includes: an optical path length adjustment portion for adjusting an optical path length of the reference beam; a position adjustment portion for adjusting a position of a focusing device for focusing the measuring beam onto the object; and a drive control portion for controlling drive of the optical path length adjustment portion and the position adjustment portion. The drive control portion is controlled based on information from a layer constituting a cross section from cross section information that is obtained in advance for a portion to be imaged of the object.

Abstract: A compensation optical apparatus for obtaining and image of an object without reduction in image quality irrespective of aberration compensation, includes: a division unit for dividing a return beam from a measured object; an aberration measurement unit for measuring an aberration caused by the measured object, with a divided beam from the division unit; an aberration compensation unit for performing aberration compensation based on the aberration measured by the aberration measurement unit; a projection unit for projecting a beam obtained by the aberration compensation in the aberration compensation unit to the measured object; an acquirement unit for acquiring a value exhibiting a state of the measured object based on the return beam from the measured object, which is obtained by the beam projected from the projection unit; and a control unit for retreating the division unit from an optical path based on the value acquired by the acquirement unit.

Abstract: An adaptive optics apparatus includes a first light modulating unit configured to perform modulation in a polarization direction of one of two polarized light components in light emitted from a light source, a changing unit configured to rotate the light modulated by the first light modulating unit by 90 degrees, a second light modulating unit configured to modulate the light changed by the changing unit in the polarization direction, and an irradiating unit configured to irradiate a measurement object with the light modulated by the second light modulating unit.

Abstract: An ophthalmic apparatus comprises: aberration correction unit arranged to correct aberration of at least one of irradiating light directed to an eye to be examined and return light from the eye; light-receiving unit arranged to receive, as return light from the eye, the light whose aberration is corrected by the aberration correction unit and then which irradiates the eye; measurement unit arranged to measure the aberration of the return light; and control unit arranged to control the aberration correction unit based on a measurement result obtained by the measurement unit and a light reception result obtained by the light-receiving unit.

Abstract: An eye examining instrument comprises a projection device and a concave screen. The eye examining instrument furthermore comprises a convex reflector, wherein an image can be projected by the projection device onto the convex reflector and reflected by the convex reflector onto the concave screen.

Abstract: An in vivo method of characterizing dynamic tear films has been developed using a near infrared phase-shifting interferometer. This interferometer continuously measures light reflected from the tear film, allowing precision analysis of the dynamic surface topography. Movies showing the tear film behavior may be generated along with quantitative metrics describing the tear film surface as it changes in time.

Abstract: A method and system for providing vision correction to a patient is disclosed. The method and system employ a vision care POD to engage and provide vision diagnostics and correction options to a patient. More specifically, method and system may include educating the population of a geographic area through sources that target particular identified groups in need of vision correction; providing an eye examination to patients using a vision care POD to generate a personalized vision correction ID card; providing one or more vision correction solution(s) to the patient; supplying the patient with the one or more vision correction solution(s) and the corresponding training for the solution(s); and providing ongoing care and support to the patient.

Abstract: One embodiment disclosed is a compact wavefront sensor module to be attached to or integrated with an ophthalmic instrument for eye examination and/or vision correction procedures. The front lens for relaying the wavefront from the eye to a wavefront sampling plane is positioned at the optical input port of the wavefront sensor module. The front lens is shared by the wavefront sensor and the ophthalmic instrument, and the wavefront sensor module can be made very compact while still being able to cover a large eye wavefront measurement diopter range. Another embodiment disclosed is an ophthalmic device for measuring properties of a subject eye including an ophthalmic instrument integrated with the wavefront sensor module.

Abstract: A viewing target for a visual acuity and refraction measurement includes at least one line comprising a width dimension that is below a resolution limit width (hereinafter “RLW”) of a test subject visual acuity, and an adjustable length dimension that is initially set at greater than the RLW of the test subject visual acuity. A base, at least approximately intersecting the line, has a thickness along the direction of the length of the line that is greater than the RLW of the test subject visual acuity. The length dimension of the line is adjustable in increments small enough to effectively approximate the visual acuity of the test subject by determining a shortest resolvable line and a next smaller line that is not resolvable by the test subject.

Abstract: In certain embodiments, determining physical lengths of an eye includes determining an optical length of each segment of a plurality of segments of an axis of the eye, where each segment corresponds to a portion of the eye. A refractive index is determined for each segment. A physical length of each segment is determined according to the optical length and the refractive index of the segment.

Abstract: A macular health measurement and storage system comprises a plurality of macular-pigment measurement machine for measuring macular pigment density in humans, a plurality of computers each of which is associated with a corresponding one the macular-pigment measuring machines, and a central host. The plurality of macular-pigment measurement machines include a device for receiving macular pigment data from a patient, at least one data transfer port, and at least one processor that enables the transfer of the macular pigment data from the transfer port. The plurality of computers include a first port coupled to the data transfer port of the corresponding macular-pigment measurement machine for receiving the macular pigment data. Each of the computers includes a second port for transferring patient data. The central host is coupled to the second ports on each of the plurality of computers. The central host includes a storage device for storing the patient data.

Abstract: A refraction device determines a refraction end point to provide corrective optics for a test subject. The device includes an adjustable optical system providing corrective optics to the test subject and an adjustable viewing target disposed along an optical path such as to be viewable through the adjustable optical system by a test subject. The adjustable viewing target includes a directional indicator linked synchronously to at least two choices of corrective optics presented to the test subject.

Abstract: System for monitoring at least one biomechanical ophthalmic parameter, the system comprising a measuring device (1) adapted to be placed on or implanted into an eye of a patient for measuring said at least one biomechanical ophthalmic parameter of said eye, a recording device (6) for obtaining from said measuring device (1) measurement data representative of the instant value of said at least one biomechanical ophthalmic parameter of said eye, wherein said recording device is adapted to obtain said measurement data at a predetermined frequency equal to or greater than twice the variation frequency of said at least one biomechanical ophthalmic parameter.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

Abstract: Provided is a hybrid laser ophthalmoscope comprising a laser light source, a LED light source, and a holographic diffuser, wherein the holographic diffuser is configured to shape a beam of light into a Maxwellian ring.

Abstract: The present invention relates to a wavefront sensor using a pair of screens, each having a two-dimensional array of circular apertures, to achieve Moiré effects, and its use to measure the slope of a wavefront.

Abstract: According to one aspect of the invention, an eyeball biological information collection device that is arranged to be worn by a subject includes a ultrasonic sensor part and a pressing part. The ultrasonic sensor part is configured to transmit an ultrasonic wave to an eyeball of the subject and receive a reflection wave of the ultrasonic wave reflected within the eyeball at a time of use of the eyeball biological information collection device. The pressing part is configured to press the ultrasonic sensor part to eyelid of the subject at the time of use.

Abstract: A wavefront sensor is integrated with a surgical microscope for allowing a doctor to make repeated wavefront measurements of a patient's eye while the patient remains on an operating table in the surgical position. The device includes a wavefront sensor optically aligned with a surgical microscope such that their fields of view at least partially overlap. The inclusion of lightweight, compact diffractive optical components in the wavefront sensor allows the integrated device to be supported on a balancing mechanism above a patient's head during a surgical procedure. As a result, the need to reposition the device and/or the patient between measuring optical properties of the eye and performing surgical procedures on the eye is eliminated. Many surgical procedures may be improved or enhanced using the integrated device, including but not limited to cataract surgery, Conductive Keratoplasty, Lasik surgery, and corneal corrective surgery.