By Dispersed Light Spectroscopy Patents (Class 356/300)
  • Patent number: 10352770
    Abstract: A system for monitoring a chemical reaction in a liquid reactor system includes a sample liquid conduit in communication with the liquid reactor system for receiving sample liquid and directing the sample liquid to an optical spectroscopy device, and a laser beam source. The optical spectroscopy device receives the laser beam from the laser source, and guides the laser beam to the sample liquid to generate an optical spectroscopy signal. A detector detects the optical spectroscopy signal and creates a detection signal responsive to the optical spectroscopy signal. A processor processes the detection signal to determine the identity and amount of at least one chemical species in the liquid. A system for continuously sampling a chemical reaction and a method for continuously monitoring and controlling a chemical reaction are also disclosed.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: July 16, 2019
    Assignee: UT-BATTELLE, LLC
    Inventors: Marissa E. Morales Rodriguez, Joanna McFarlane
  • Patent number: 10337919
    Abstract: A PDA 5 has a plurality of light receiving elements. An A/D converter 30 converts an output signal from each of the light receiving elements of the PDA 5. A conversion processing unit 42 sequentially executes, for the plurality of light receiving elements, a conversion process of converting an output signal from an identical one of the light receiving elements at least twice within a preset time range with the A/D converter 30, to acquire at least two output values. An average value calculation unit 43 calculates an average value of the at least two output values for each of the light receiving elements acquired by the process executed by the conversion processing unit 42.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: July 2, 2019
    Assignee: SHIMADZU CORPORATION
    Inventor: Yugo Ishihara
  • Patent number: 10333646
    Abstract: Optical multiplexers, optical demultiplexers, optical modules including the same, and methods of making and using the same are disclosed. The optical multiplexers include first and second structural blocks and a beam combiner. The first and second structural blocks each include at least one mirror and at least one filter, and are configured to combine a plurality of individual optical signals into a multi-channel optical signal. The beam combiner includes one or more mirrors and one or more filters, and is configured to combine the multi-channel optical signals into a further multi-channel optical output signal having the same number of channels as the multi-channel optical signals. The optical demultiplexers are structurally similar to the optical multiplexers, but provide a complementary or reverse function.
    Type: Grant
    Filed: December 26, 2016
    Date of Patent: June 25, 2019
    Assignee: Source Photonics (Chengdu) Co., Ltd.
    Inventors: Chao Tian, Jian Yang, Shengzhong Zhang, Mark Heimbuch
  • Patent number: 10330927
    Abstract: An optical system images an object region with an optical beam path in an image plane of an image acquisition system. The optical system includes a first optical assembly through which the optical beam path passes and a second optical assembly arranged in the optical beam path on the side of the first optical assembly facing away from the object region. The second optical assembly is a system at least partly compensating longitudinal chromatic aberrations of the first optical assembly occurring in the wavelength range 625 nm???850 nm of the light.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: June 25, 2019
    Assignee: Carl Zeiss Meditec AG
    Inventors: Artur Hoegele, Thomas Nobis
  • Patent number: 10295408
    Abstract: A spectroscopy system (10) for analyzing in-elastic scattered electromagnetic radiation from an object being irradiated by electromagnetic radiation is provided. The system comprises a tunable lens assembly (13) having a tunable lens provided in the beam path between an electromagnetic radiation source (11) and the object (0) and arranged to project a beam of electromagnetic radiation emitted from the electromagnetic radiation source onto an area of the object and receive and collimate the in-elastic scattered electromagnetic radiation from the object. Based on electromagnetic radiation detected by at least a first detector (121) a control unit (14) is capable making a decision to change the operational settings of the tunable lens.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: May 21, 2019
    Assignee: SERSTECH AB
    Inventors: Katja Szybek, Jan Sonnvik
  • Patent number: 10288557
    Abstract: The instant disclosure provides spectrophotometric methods for assessing histological stains used in a histology analyzer. The methods find use in various assessments including determinations of the identity of a histological stain, determinations of the quality of a histological stain, etc. Also included are devices and systems for practicing the described methods. The instant disclosure also provides computer readable media containing libraries of reference spectrophotometric characteristics of histological stains useful in assessing a histological stain used in a histology analyzer. Also provided is computer readable media containing instructions that cause a computing device to perform steps for making an assessment of a histological stain.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: May 14, 2019
    Assignee: Abbott Laboratories
    Inventors: Svitlana Y. Berezhna, Rene Nieves Alicea, Ema C. Olah
  • Patent number: 10281327
    Abstract: An apparatus for analyzing light includes an input aperture for receiving light; a first set of one or more lenses configured to relay light from the input aperture; and a prism assembly configured to disperse light from the first set of one or more lenses. The prism assembly includes a plurality of prisms that includes a first prism, a second prism that is distinct from the first prism, and a third prism that is distinct from the first prism and the second prism. The first prism is mechanically coupled with the second prism and the second prism is mechanically coupled with the third prism. The apparatus also includes a second set of one or more lenses configured to focus the dispersed light from the prism assembly; and an array detector configured for converting the light from the second set of one or more lenses to electrical signals.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: May 7, 2019
    Assignee: STRATIO
    Inventors: Jae Hyung Lee, Youngsik Kim, Yeul Na, Juhyung Kang
  • Patent number: 10282649
    Abstract: When the intensity of visible light is properly modulated, the difference between the modulated visible light and the original visible light is not noticeable to human eyes but detectable to electronic devices. Thus, the modulated visible light may be utilized to form patterns that are only recognizable to electronic devices but not to human eyes.
    Type: Grant
    Filed: August 19, 2014
    Date of Patent: May 7, 2019
    Assignee: Empire Technology Development, LLC
    Inventor: Zhen Xiao
  • Patent number: 10281262
    Abstract: An imaging laser range finder including an objective lens having an optical axis, an object side, and an image side, a controllable pixelated light modulator disposed along the optical axis on the image side of the lens, and a detector disposed optically downstream from the pixelated light modulator on the image side of the lens. The controllable pixelated light modulator is advantageously a MEMS-based system such as a digital mirror device (DMD). An increased field of view may be obtained by incorporating a pair of opposing surface reflectors between an imaging lens and the controllable pixelated light modulator. Associated methods are disclosed.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: May 7, 2019
    Assignee: Arizona Board of Regents on Behalf of the University of Arizona
    Inventor: Yuzuru Takashima
  • Patent number: 10258236
    Abstract: A spectrometer includes an illuminating section; a receiving section configured to detect radiation reflected from an object including an optically inhomogeneous scattering medium; a hardware section configured to obtain a solution of an inverse problem to reconstruct an absorption spectrum of the optically inhomogeneous scattering medium, wherein the illuminating section includes at least one light-emitting diode source, a radiation spectral curve of which is divided, by at least two spectral filters having different spectral transmission curves, into at least two spectral regions, to form an equivalent radiation spectrum from at least two spectral sources, and wherein the hardware section applies the solution of the inverse problem based on information about a spectral content of the radiation of the illuminating section, a signal obtained in a form of a response from the optically inhomogeneous scattering medium, and a spectral sensitivity curve of the receiving section.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: April 16, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Alexey Grigor{grave over ( )}evich Anikanov, Sergey Vasil{grave over ( )}evich Afanasyev, Vladislav Vladimirovich Druzhin, Alexander Victorovich Morozov
  • Patent number: 10262413
    Abstract: A soil imaging system having a work layer sensor disposed on an agricultural implement to generate an electromagnetic field through a soil area of interest as the agricultural implement traverses a field. A monitor in communication with the work layer sensor is adapted to generate a work layer image of the soil layer of interest based on the generated electromagnetic field. The work layer sensor may also generate a reference image by generating an electromagnetic field through undisturbed soil. The monitor may compare at least one characteristic of the reference image with at least one characteristic of the work layer image to generate a characterized image of the work layer of interest. The monitor may display operator feedback and may effect operational control of the agricultural implement based on the characterized image.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: April 16, 2019
    Assignee: THE CLIMATE CORPORATION
    Inventors: Michael Strnad, Roger Koch, Dale Koch
  • Patent number: 10241042
    Abstract: A wearable device, a charger, and a method for estimating absorbance of the wearable device are provided. The wearable device includes a spectroscope configured to emit a first light to a reference material of a charger, measure an intensity of the first light reflected from the reference material, emit a second light to a skin of a user, and measure an intensity of the second light reflected from the skin of the user; and a processor configured to determine absorbance of the skin of the user based on the intensity of the first light and the intensity of the second light.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: March 26, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventor: Sang Kyu Kim
  • Patent number: 10228399
    Abstract: A smart sensor system can include one or more configurable input and output channels, each configurable channel including one or more switches configured to activate the input and/or output and/or to select a type of input and/or output signal, at least one analog-to-digital converter and at least one digital-to-analog converter operatively connected to the one or more switches for the one or more configurable channels, and at least one controller configured to control the configurable channels.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: March 12, 2019
    Assignee: Simmonds Precision Products, Inc.
    Inventors: Benjamin D. McBride, Peter J. Carini, Matthew B. Burleigh, Travis Gang, Joel Nelson
  • Patent number: 10228330
    Abstract: A gemstone testing apparatus with an apparatus body, a reflector housing with a light reflective layer at its interior surface, a transparent housing portion that is transparent for ultraviolet light, and a detector probe that is protruding from the transparent housing portion. An UV light emitter is provided within the reflector housing, which is adapted for directing the UV light through the transparent housing portion into the vicinity of a tip of the detector probe.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: March 12, 2019
    Assignee: Jubilee Diamond Instrument (S) Pte. Ltd.
    Inventor: Kui Lim Tam
  • Patent number: 10228551
    Abstract: A chromatic confocal measuring device includes a light source, which emits light of a plurality of wavelengths, and a first beam splitter, via which the light from the light source into an imaging optical unit having chromatic aberration on. Light reflected from the measurement object is imaged by the imaging optical unit and the first beam splitter onto a first confocal detection stop arrangement, such that the first confocal detection stop arrangement functions as a confocal aperture. Light incident through the first detection stop arrangement is detected and evaluated by a first detection device. The measuring device has a first slit stop, which functions as a confocal aperture of the measuring device. The measuring device additionally includes a second detection device and a second beam splitter, wherein the second beam splitter splits the light reflected from the measurement object into a first and a second partial beam, which image the same spatial region of the measurement object.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: March 12, 2019
    Assignee: PRECITEC OPTRONIK GMBH
    Inventors: Christoph Dietz, Martin Schönleber, Jean-Francois Pichot
  • Patent number: 10215958
    Abstract: An optical imaging lens is configured to allow imaging rays to pass through a first curved surface of an optical element and the optical imaging lens in sequence. The optical imaging lens includes first, second and last lens element arranged in a sequence. One of the object-side surface and the image-side surface of the last lens element is a second curved surface. A cross-sectional line of the second curved surface of the last lens element obtained by cutting the second curved surface of the last lens element along a plane parallel to the XZ plane is a second curved line. A material of at least one of the first lens element to the last lens element is a plastic material.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: February 26, 2019
    Assignee: Genius Electronic Optical Co., Ltd.
    Inventor: Matthew Bone
  • Patent number: 10213113
    Abstract: A wearable device includes a measurement device adapted to be placed on a wrist or ear having a light source with LEDs to measure physiological parameters. The measurement device generates an optical beam having a near infrared wavelength between 700-2500 nanometers by modulating the LEDs, and lenses to deliver the beam to tissue, which reflects the beam to a receiver having spectral filters in front of spatially separated detectors coupled to analog to digital converters that generate at least two receiver outputs. Signal-to-noise ratio of the beam reflected from the tissue is improved by comparing the receiver outputs, and by increasing light intensity from the LEDs. The receiver is synchronized to the modulation of the LEDs and uses a lock-in technique that detects the modulation frequency. The measurement device generates an output signal representing a non-invasive measurement on blood within the tissue.
    Type: Grant
    Filed: June 24, 2018
    Date of Patent: February 26, 2019
    Assignee: OMNI MEDSCI, INC.
    Inventor: Mohammed N. Islam
  • Patent number: 10208321
    Abstract: A method comprising a series of selective extraction techniques for the parallel production of biodiesel and isolation of several valuable co-products including an alkenone hydrocarbon mixture of the kerosene/jet fuel range (primarily C10-, C12-, and C17-hydrocarbons) and fucoxanthin, a high-valued carotenoid, from the marine alkenone-producing microalgae Isochrysis.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: February 19, 2019
    Assignees: Woods Hole Oceanographic Institution, Western Washington University
    Inventors: Christopher M. Reddy, Gregory W. O'Neil
  • Patent number: 10201283
    Abstract: A smart phone or tablet includes pulsed laser diodes generating light with near-infrared wavelengths between 700-2500 nanometers. First lenses direct light from the laser diodes to tissue. An array of pulsed laser diodes generates light with near-infrared wavelengths between 700-2500 nanometers. Second lenses form light from the array into spots directed on the tissue. An infrared camera synchronized to the laser diodes and the array generates data based on light reflected from the tissue. The smart phone or tablet generates a two-dimensional or three-dimensional image using the data from the infrared camera. The smart phone or tablet includes a wireless receiver, a wireless transmitter, a display, a voice input module, and a speaker.
    Type: Grant
    Filed: July 8, 2018
    Date of Patent: February 12, 2019
    Assignee: OMNI MEDSCI, INC.
    Inventor: Mohammed N. Islam
  • Patent number: 10194803
    Abstract: A control apparatus includes a data acquiring unit configured to acquire a measured signal obtained by measuring light emitted from a test object onto which light is irradiated, a processing unit configured to calculate an objective function that varies in accordance with a statistical value obtained by statistically processing the measured signal, and a controller configured to control a modulation amount of a wavefront of the light irradiated onto the test object so as to minimize the objective function.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: February 5, 2019
    Assignee: CANON KABUSHIKI KAISHA
    Inventor: Takahiro Masumura
  • Patent number: 10198790
    Abstract: Described in this disclosure is a space-variant Multi-domain Foveated Compressive Sensing (MFCS) system for adaptive imaging with variable resolution in spatial, polarization, and spectral domains simultaneously and with very low latency between multiple adaptable regions of interest (ROIs) across the field of view (FOV). The MFCS system combines space-variant foveated compressive sensing (FCS) imaging covered by a previous disclosure with a unique dual-path high efficiency optical architecture for parallel multi-domain compressive sensing (CS) processing. A single programmable Digital Micromirror Device (DMD) micro-mirror array is used at the input aperture to adaptively define and vary the resolution of multiple variable-sized ROIs across the FOV, encode the light for CS reconstruction, and adaptively divide the input light among multiple optical paths using complementary measurement codes, which can then be reconstructed as desired.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: February 5, 2019
    Assignee: HRL Laboratories, LLC
    Inventors: Yuri Owechko, Daniel Yap, Oleg M. Efimov
  • Patent number: 10188299
    Abstract: A wearable device for measuring physiological parameters includes a light source having a plurality of semiconductor light emitting diodes (LEDs) each configured to generate an output optical beam, wherein at least a portion of the one or more optical beam wavelengths is a near-infrared wavelength. The light source is configured to increase signal-to-noise ratio by increasing light intensity for at least one of the LEDs and by increasing a pulse rate of at least one of the LEDs. A lens is configured to receive the output optical beam and to deliver a lens output beam to tissue. A detection system generates an output signal in response to the lens output beam reflected from the tissue, wherein the detection system is configured to be synchronized to the light source, and is located a different distance from a first one of the LEDs than a second one of the LEDs.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: January 29, 2019
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 10190866
    Abstract: The embodiments of the present disclosure relate to a Fabry-Perot cavity, a manufacturing method thereof, an interferometer and a measuring method for wavelength of light. The Fabry-Perot cavity includes two parallel substrates and a liquid crystal layer between the two parallel substrates, and a sealed cavity is defined between the two substrates; wherein the two substrates comprise a first substrate and a second substrate, light could enter through the first substrate and run out from the second substrate via the liquid crystal layer, and a deflection angle of the liquid crystal layer could be changed by applying various voltage between the two substrates.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: January 29, 2019
    Assignee: BOE TECHNOLOGY GROUP CO., LTD.
    Inventor: Zhongxiao Li
  • Patent number: 10184833
    Abstract: An imaging spectrometer receives a beam of light from a slit and outputs the beam of light to a focal plane. The output beam of light at the focal plane is dispersed in accordance with a spectral composition of the beam of light received from the slit. The imaging spectrometer comprises first to fourth curved reflective portions. The first to fourth curved reflective portions are arranged so that the beam of light, in its passage from the slit to the focal plane, sequentially strikes the first to fourth curved reflective portions and is reflected by the first to fourth curved reflective portions. Further, the first to fourth curved reflective portions are alternatingly concave or convex, respectively, along the passage of the beam of light. At least one of the first to fourth curved reflective portions has a reflective grating structure. Further disclosed is a method of manufacturing such imaging spectrometer.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: January 22, 2019
    Assignee: European Space Agency
    Inventors: Matteo Taccola, Munadi Ahmad
  • Patent number: 10184888
    Abstract: A device for determining a refractive index may be provided. The device including at least one waveguide having a core and a cladding surrounding the core, the cladding being at least partly removed in at least one first longitudinal portion and the core including at least one fiber Bragg grating in at least one second longitudinal portion. A method for determining a refractive index or a pressure change in a fluid may also provided. The method may include at least one waveguide having a core and a cladding surrounding the core, the cladding being at least partly removed in at least one longitudinal portion. A method for producing such a device may also be provided.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: January 22, 2019
    Assignees: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V., TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Wolfgang Schade, Jörg Burgmeier, Anna Lena Baumann, Björn Reinhard
  • Patent number: 10172520
    Abstract: A sensing device allows detection of biological quantities in ways that are minimally invasive. Micrometer or nanometer sized needles allow sensing of bodily fluids in a minimally invasive method. The device comprises electronics and power harvesting. Antennas or coils allow communication and power harvesting from an external device, which can be attached to smartphones to allow operation of a camera and camera light for biosensing.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: January 8, 2019
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Axel Scherer, Muhammad Mujeeb-U-Rahman, Meisam Honavar Nazari, Muhammad Musab Jilani
  • Patent number: 10172523
    Abstract: A measurement system includes a light source having semiconductor sources, a multiplexer, and one or more fused silica fibers configured to form an output optical beam having one or more optical wavelengths modulated at a modulation frequency. A light beam set-up includes a monochromator forming a filtered optical beam. A measurement apparatus delivers the filtered optical beam to a sample. A receiver receives a spectroscopy output beam generated from the sample by the filtered optical beam. The receiver is configured to use a lock-in technique that detects the modulation frequency, and to generate first and second signals responsive to light received while the light source is off and on, respectively. The measurement system improves a signal-to-noise ratio of the spectroscopy output beam by differencing the first and second signals. The receiver processes the spectroscopy output beam using chemometrics or multivariate analysis to permit identification of materials within the sample.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: January 8, 2019
    Assignee: OMNI MEDSCI, INC.
    Inventor: Mohammed N. Islam
  • Patent number: 10136819
    Abstract: An imaging device includes laser diodes (LDs) generating near-infrared wavelength light, lenses configured to deliver the light to tissue, a first receiver having one or more detectors, and a first part with at least one of the LDs capable of being pulsed. The first receiver receives light reflected from the tissue and is synchronized to the pulsed light and configured to perform a time-of-flight measurement. An infrared camera receives light reflected by the tissue from a second part of the imaging device. The camera captures light while the second part is off, and while the second part is on to generate corresponding signals, and differences the signals to generate an image. An array of LDs generates a grid of spots on the tissue, which is reflected to the camera. A coupled phone, tablet, or computer receives and processes the time-of-flight measurement, the image, and the reflected grid of spots.
    Type: Grant
    Filed: February 4, 2018
    Date of Patent: November 27, 2018
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 10126283
    Abstract: A smart phone or tablet includes laser diodes configured to be pulsed and generate near-infrared light between 700-2500 nanometers. Lenses direct the light to a sample. A detection system includes a photodiode array with pixels coupled to CMOS transistors, and is configured to receive light reflected from the sample, to be synchronized to the light from the laser diodes, and to perform a time-of-flight measurement of a time difference between light from the laser diodes and light reflected from the sample. The detection system is configured to convert light received while the laser diodes are off into a first signal, and light received while at least one laser diodes is on, which includes light reflected from the sample, into a second signal. The smart phone or tablet is configured to difference the first signal and the second signal and to generate a two-dimensional or three-dimensional image using the time-of-flight measurement.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: November 13, 2018
    Assignee: Omni MedSci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 10105059
    Abstract: A wearable device for measuring physiological parameters includes a light source having a plurality of semiconductor light emitting diodes (LEDs) each configured to generate an output optical beam, wherein at least a portion of the one or more optical beam wavelengths is a near-infrared wavelength. The light source is configured to increase signal-to-noise ratio by increasing light intensity for at least one of the LEDs and by increasing a pulse rate of at least one of the LEDs. A lens is configured to receive the output optical beam and to deliver a lens output beam to tissue. A detection system generates an output signal in response to the lens output beam reflected from the tissue, wherein the detection system is configured to be synchronized to the light source, and is located a different distance from a first one of the LEDs than a second one of the LEDs.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: October 23, 2018
    Assignee: OMNI MEDSCI, INC.
    Inventor: Mohammed N. Islam
  • Patent number: 10107741
    Abstract: Systems and methods of the present disclosure are directed to detecting species within a fluid using a multi-pass absorption cell and a spectrometer. The absorption cell includes a plurality of mirrors arranged in a manner such that a detection light traverses multiple passes through the fluid within the absorption cell. In some implementations, the detection light is reflected by the plurality of mirrors to form optical paths in more than one plane. The system also includes an electronic unit configured to receive and process spectral data from the spectrometer. In some implementations, the electronic unit communicates with at least one computational unit over a communication interface to send a portion of the spectral data for processing. The electronic unit may also receive processed data from the computational unit.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: October 23, 2018
    Assignee: DUVAS TECHNOLOGIES LIMITED
    Inventor: Craig Sawyers
  • Patent number: 10107852
    Abstract: A method and an apparatus check a multiplicity of mutually insulated strands in a stator winding bar of an electric machine. The method includes injecting a test signal, determining a first component of the test signal, and comparing at least the first component with a reference signal in order to determine damage to insulation between individual strands of the multiplicity of strands. The apparatus includes a signal source and a measuring apparatus. The method and the apparatus are particularly suitable for checking stator winding bars as are used in a generator and/or an electric motor.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: October 23, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventor: Christian Staubach
  • Patent number: 10098546
    Abstract: A wearable device includes a measurement device having light emitting diodes (LEDs) measuring a physiological parameter. The measurement device modulates the LEDs to generate an optical beam having a near-infrared wavelength between 700-2500 nanometers. Lenses receive and deliver the optical beam to tissue, which reflects the optical beam to a receiver having spatially separated detectors coupled to analog-to-digital converters configured to generate receiver outputs. The receiver captures light while the LEDs are off, and reflected light from the tissue while the LEDs are on, to generate first and second signals, respectively. Signal-to-noise ratio is improved by differencing the first and second signals and by differencing the receiver outputs. The measurement device further improves signal-to-noise ratio of the reflected optical beam by increasing light intensity of the LEDs relative to an initial light intensity.
    Type: Grant
    Filed: January 2, 2018
    Date of Patent: October 16, 2018
    Assignee: OMNI MEDSCI, INC.
    Inventor: Mohammed N. Islam
  • Patent number: 10096110
    Abstract: This invention relates to a system and method for applying an ensemble of segmentations to microscopy images of a tissue sample to determine if the tissue sample is representative of cancerous tissue. The ensemble of segmentations is applied to a plurality of greyscale or color microscopy images to generate a final image level segmentation and a final blob level segmentation. The final image level segmentation and final blob level segmentation are used to calculate a mean nuclear volume to determine if the tissue sample is representative of cancerous tissue.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: October 9, 2018
    Assignees: University of South Florida, Stereology Resource Center, Inc.
    Inventors: Peter Randolph Mouton, Dmitry Goldgof, Lawrence O. Hall, Baishali Chaudhury
  • Patent number: 10078013
    Abstract: The invention provides methods and apparatus comprising a multi-wavelength laser source that uses a single unfocused pulse of a low intensity but high power laser over a large sample area to collect Raman scattered collimated light, which is then Rayleigh filtered and focused using a singlet lens into a stacked fiber bundle connected to a customized spectrograph, which separates the individual spectra from the scattered wavelengths using a hybrid diffraction grating for collection onto spectra-specific sections of an array photodetector to measure spectral intensity and thereby identify one or more compounds in the sample.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: September 18, 2018
    Assignee: University of Maryland Baltimore County
    Inventors: Bradley Arnold, Christopher Cooper, John Cataldi
  • Patent number: 10071205
    Abstract: Apparatus for determining information associated with reflection characteristics of a surface comprising a sensor (60) configured to generate sensor output dependent on an intensity of light incident on the sensor and having a field of view directed at an external surface (57) in use; an illumination source (58) configured to emit light onto the external surface in use; an optically transparent window (61) located such as to allow light to pass from the illumination source to the external surface and to allow light to pass to the sensor from the external surface in use; a light concentrator (66) fixed to or integral with the window, the light concentrator being configured to concentrate at least some light from the illumination source onto the external surface in use such that the concentrated light may be reflected from the external surface onto the sensor via the window; and a processor (40) configured to use the sensor output to determine information associated with reflection characteristics of the extern
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: September 11, 2018
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Gertrud Blei, Gunter Heumann
  • Patent number: 10048567
    Abstract: An electronic light synthesizer electronically synthesizes supercontinuum light and includes: a microwave modulator that: receives a continuous wave light including an optical frequency; modulates the continuous wave light at a microwave repetition frequency; and produces a frequency comb modulated at the microwave repetition frequency; a self-phase modulator that: receives the frequency comb; spectrally broadens an optical wavelength range of the frequency comb; and produces broadened light modulated at the microwave repetition frequency; an optical filter that: receives the broadened light from the self-phase modulator; and optically filters electronic noise in the broadened light; and a supercontinuum generator that: receives the broadened light from the optical filter; spectrally broadens the optical wavelength range of the broadened light; and produces supercontinuum light modulated at the microwave repetition frequency.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: August 14, 2018
    Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Scott Papp, Scott Diddams, Katja Beha, Daniel Cole
  • Patent number: 10028663
    Abstract: In a photoacoustic measurement apparatus and a probe, artifacts due to photoacoustic waves generated in a surface portion of a subject are reduced without increasing the repetition period of photoacoustic measurement. A measurement light emitting unit emits measurement light toward a subject. An acoustic wave detector detects photoacoustic waves generated within the subject due to the measurement light. A correction light source emits correction light toward the subject. A light intensity detector detects reflected light generated by reflection of the correction light, which is emitted toward the subject, from the subject. In a probe, the correction light source and the light intensity detector are disposed between the measurement light emitting unit and the acoustic wave detector.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: July 24, 2018
    Assignee: FUJIFILM Corporation
    Inventors: Atsushi Hashimoto, Kaku Irisawa
  • Patent number: 10031077
    Abstract: A spectroscopy system comprising at least two laser modules, each of the laser modules including a laser cavity, a quantum cascade gain chip for amplifying light within the laser cavity, and a tuning element for controlling a wavelength of light generated by the modules. Combining optics are used to combine the light generated by the at least two laser modules into a single beam and a sample detector detects the single beam returning from a sample.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: July 24, 2018
    Assignee: Block Engineering, LLC
    Inventors: Petros Kotidis, Erik Deutsch, Ninghui Zhu, Dan Cavicchio
  • Patent number: 10020635
    Abstract: A spectrometer device may include a first QCL configured to operate in a frequency comb mode with spectrally equidistant modes with stable relative phase, a power supply coupled to the first QCL, and a controller coupled to the power supply. The first QCL may include different active region layers based on a vertical transition. The first QCL may be configured to provide a comb output having a cumulative flat gain profile and reduced dispersion refractive index profile in a broad range of driving conditions. The spectrometer device may include a sample cell configured to receive the comb output.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: July 10, 2018
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventor: Arkadiy Lyakh
  • Patent number: 10012543
    Abstract: An imaging optical system including a plurality of imaging optical sub-systems, each having at least one optical element and receiving light from a source, and a plurality of spectrometer optical sub-systems, each spectrometer optical sub-system receiving light from at least one of the imaging optical sub-systems, each imaging optical sub-system and spectrometer optical sub-system combination having a spatial distortion characteristic, each spatial distortion characteristic having a predetermined relationship to the other spatial distortion characteristics.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: July 3, 2018
    Assignee: WAVEFRONT RESEARCH, INC.
    Inventor: Thomas A. Mitchell
  • Patent number: 9995722
    Abstract: A measurement system includes a light source having semiconductor sources configured to generate an input optical beam, a multiplexer configured form an intermediate optical beam from the input optical beam, fibers including a fused silica fiber configured to receive the intermediate optical beam and to form an output optical beam. The output optical beam comprises wavelengths between 700 and 2500 nanometers with a bandwidth of at least 10 nanometers. A measurement apparatus is configured to deliver the output beam to a sample to generate a spectroscopy output beam. A receiver is configured to receive and process the spectroscopy output beam to generate an output signal, wherein the receiver processing includes chemometrics or multivariate analysis methods to permit identification of materials within the sample, the light source and the receiver are remote from the sample, and the sample includes plastics or food industry goods.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: June 12, 2018
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 9983138
    Abstract: A method for determining whether a sample includes a nitrate-based explosive comprises receiving the sample and selecting an area of interest on the sample. Then, at least a portion of the area of interest is interrogated with an optical source to produce a spectrum with an amplitude. The amplitude of a first portion of the spectrum is compared to a first predetermined threshold to determine if the sample includes a nitrate. After determining that the sample includes a nitrate in the area of interest, the amplitude of a second portion of the spectrum is compared to a second predetermined threshold to determine if the sample includes a secondary indicator. Then, an indicator is activated based on the determinations.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: May 29, 2018
    Assignee: Battelle Memorial Institute
    Inventors: Andrew P. Bartko, Theodore J. Ronningen
  • Patent number: 9927298
    Abstract: A spectroscopic measurement apparatus includes a light source, a diffraction grating being a spectroscopic unit, a spatial filter unit, a detection unit, and an analysis unit. The diffraction grating spatially disperses light from the light source, and outputs the light to different optical paths according to a wavelength. The spatial filter unit inputs the light from the diffraction grating to different positions according to the wavelength, applies loss depending on the wavelength to the light, and outputs the light. The detection unit detects the intensity of the light from the spatial filter unit. The analysis unit obtains the intensities of light in an absorption band and light in a non-absorption band of a component in a measurement sample on an optical path between the light source and the detection unit based on the detection result, and evaluates the component in the measurement sample.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: March 27, 2018
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Yoichi Kawada, Yoshiyuki Shimizu, Toyohiko Yamauchi
  • Patent number: 9897584
    Abstract: A measurement system performs non-destructive quality control or constitutive analysis using a light source generating an output optical beam using semiconductor sources that generate an input optical beam, a multiplexer configured to receive the input beam and to form an intermediate optical beam, and fibers configured to receive the intermediate beam and to form the output beam. The fibers include a fused silica fiber having a core diameter less than 400 microns. The output beam includes wavelengths between 700 and 2500 nanometers and has a bandwidth of at least 10 nanometers. The system includes a measurement apparatus that receives the output beam and delivers the beam to a sample to generate a spectroscopy beam. A receiver is configured to receive the spectroscopy beam and process the beam to generate an output signal. The light source and receiver are remote from the sample, which includes plastics or food industry goods.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: February 20, 2018
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 9885698
    Abstract: A wearable device for use with a smart phone or tablet includes a measurement device having a light source with a plurality of light emitting diodes (LEDs) for measuring physiological parameters and configured to generate an optical beam with wavelengths including a near-infrared wavelength between 700 and 2500 nanometers. The measurement device includes lenses configured to deliver the optical beam to a sample of skin or tissue, which reflects the optical beam to a receiver located a first distance from one of the LEDs and a different distance from another of the LEDs, and is also configured to generate an output signal representing a non-invasive measurement on blood contained within the sample. The wearable device is configured to communicate with the smart phone or tablet, which receives, processes, stores and displays the output signal with the processed output signal configured to be transmitted over a wireless transmission link.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: February 6, 2018
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 9869637
    Abstract: A detector apparatus is provided and includes a collector having access to a sample of a gaseous fluid and a tester coupled to and disposed remotely from the collector. The tester includes a test chamber into which a sample is directed from the collector, an excitation element to excite the sample in the test chamber and a spectrum analyzing device coupled to the test chamber to analyze the excited sample for evidence of a concentration of particles of interest in the gaseous fluid exceeding a threshold concentration. The threshold concentration is defined in accordance with a type of the particles of interest and a residence time of the sample.
    Type: Grant
    Filed: June 8, 2015
    Date of Patent: January 16, 2018
    Assignee: RAYTHEON COMPANY
    Inventors: Eric J. Griffin, Kalin Spariosu, Erik D. Johnson
  • Patent number: 9861286
    Abstract: A wearable device for use with a smart phone or tablet includes LEDs for measuring physiological parameters by modulating the LEDs and generating a near-infrared multi-wavelength optical beam. At least one LED emits at a first wavelength having a first penetration depth and at least another LED emits at a second wavelength having a second penetration depth into tissue. The device includes lenses that deliver the optical beam to the tissue, which reflects the first and second wavelengths. A receiver is configured to capture light while the LEDs are off and while at least one of the LEDs is on and to difference corresponding signals to improve a signal-to-noise ratio of the optical beam reflected from the tissue. The signal-to-noise ratio is further increased by increasing light intensity of at least one of the LEDs. The device generates an output signal representing a non-invasive measurement on blood within the tissue.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: January 9, 2018
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 9855588
    Abstract: A method and device for separating at least one catalyst from a mixture of homogeneously shaped catalysts, the catalysts comprising at least one metal selected from the group formed by Ni, Co, Mo, W, the catalyst to be separated comprising a characteristic metal selected from the group formed by Ni, Co, Mo, W and the other catalysts of the mixture not containing said characteristic metal, in which method: the grains of the catalyst of said mixture pass in front of the LIBS detection system, the presence of said characteristic metal in the catalysts is detected by the LIBS technique, the wavelength being selected so as to detect said characteristic metal, the LIBS detection system sends a signal to a means for evacuating grains of catalyst to be separated in a manner such as to separate said grains from the other catalysts of said mixture.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: January 2, 2018
    Assignee: IFP Energies Nouvelles
    Inventors: Thierry Gauthier, Charles Philippe Lienemann
  • Patent number: 9833147
    Abstract: A mammography device is disclosed. The mammography device includes a container configured to surround the breast and a plurality of optical fibers attached to be directed inward in the container and configured to perform radiation and detection of light. The container has a base member having an opening, a plurality of annular members continuously disposed to come in communication with the opening, and a bottom member disposed inside the annular member spaced the farthest distance from the base member. The annular members and the bottom member are configured to relatively displace the adjacent annular member on the side of the base member or the base member in a communication direction. Some of the plurality of optical fibers is attached to the plurality of annular members.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: December 5, 2017
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Toshihiko Suzuki, Yutaka Yamashita, Yukio Ueda, Etsuko Yamaki, Daisuke Yamashita, Kenji Yoshimoto, Harumi Sakahara, Hiroyuki Ogura, Hatsuko Nasu