Abstract: An apparatus (110) includes an activation mechanism (20) and a safety latch (122). The activation mechanism is operative to deploy a needle (116) to protrude out of a housing (112), the needle (116) having a longitudinal axis. The safety latch (122) is movably mounted on the housing (112) and formed with a needle opening (129) to allow the needle (116) to pass therethrough. The safety latch (122) has a first position wherein the needle (116) is aligned to pass through the needle opening (129) and a second position wherein the safety latch (122) is moved with respect to the housing (112) such that the needle (116) is blocked from movement in a direction parallel to the longitudinal axis thereof by a portion of the safety latch (122) distanced from the needle opening (129).

Abstract: A biological parameter displaying apparatus includes: a coordinate displaying unit which displays first coordinates in which a first biological parameter of a patient, which is measured by a first measuring unit, is set as an X-axis, and a second biological parameter of the patient, which is different in kind from the first biological parameter and which is measured by a second measuring unit, is set as a Y-axis; a plot data producing unit which produces first plot data, each of the first plot data being produced based on first measurement values of the first and second biological parameters which are measured at a same time or in a same time zone; and a plot displaying unit which plots the first plot data in the first coordinates.

Abstract: A consciousness level determination apparatus calculates a heart rate interval from a heart rate signal of a subject and calculates a spectral density of each frequency by performing a frequency analysis on the calculated heart rate interval. The apparatus extracts, at each predetermined timing, a combination of a maximum density that is a maximum, a maximum frequency that is a frequency corresponding to the maximum density, and a magnitude difference relation that represents a difference between the maximum density and spectrum densities which correspond to frequencies adjoined to the maximum frequency. The apparatus compares the combination with a combination extracted at a previous timing. The apparatus determines a consciousness level on the basis of a determination reference that is determined by using a result of the comparison.

Abstract: A method for measuring reactive hyperemia in a subject is disclosed. The method includes performing a first segmental cuff plethysmography to generate a baseline arterial compliance curve and/or a baseline pressure-area (P-A) curve, performing a second segmental cuff plethysmography to generate a hyperemic arterial compliance curve and/or a hyperemic P-A curve, and calculating an area between the baseline and the hyperemic curves. The size of the area can be used as an indication of endothelial dysfunction (ED) and ED-related diseases.

Abstract: A first calculation unit receives phase characteristics Pa(f) and Pb(f) outputted from frequency transform units, calculates a propagation time difference based on a phase difference between the two phase characteristics in a high-frequency component thereof, and calculates a pulse wave velocity by dividing a difference in the distances of vascular pathways from the heart to respective measurement areas. Meanwhile, a second calculation unit calculates a pulse wave velocity by dividing the stated difference in the distances by a appearance time difference at a predetermined position in respective pulse waveforms obtained by rendering the measurement signals Pa(t) and Pb(t) on a time axis. A comparison unit compares the pulse wave velocities, and in the case where the ratio thereof is outside a predetermined range, an evaluation result indicating that it is possible that a predetermined pathologic change is present in the vascular pathway is outputted to a display processing unit.

Abstract: Anomalies are detected in a network by detecting communication between a plurality of entities and a set of users in the network, determining an overlap between subsets of the set of users that the entities comprising the plurality of entities communicated with, respectively, and determining whether the communication between the plurality of entities and the set of users is anomalous based on the overlap.

Abstract: Wearable devices are described herein including at least two photodetectors and a mount configured to mount the at least two photodetectors to an external surface of a wearer. The at least two photodetectors are configured to detect alignment between the wearable device and a target on or in the body of the wearer (e.g., to detect the location of vasculature within the body of the wearer relative to the at least two photodetectors). Alignment of the at least two photodetectors relative to the target could enable detection of one or more physiological properties of the wearer. For example, the wearable device could include a sensor configured to detect a property of the target when the sensor is above the target, and alignment of the target relative to the at least two photodetectors could include the sensor being located above the target.

Abstract: Apparatus, systems and methods for cooling or warming the temperature of all or a portion of the body of a human or animal subject to treat disorders including but not limited to sepsis, septic shock or other inflammatory or infectious conditions which can result in shock, hypoxia, ischemia and/or multiple organ failure in human or animal subjects.

Abstract: A method and device for estimating central aortic pulse pressure by cuff pressure pulse wave oscillation signals. The method comprises (I) providing an equation for estimating central aortic pulse pressure; (II) measuring pressure pulse wave oscillation signals in a cuff, which comprise a brachial systolic blood pressure, a diastolic blood pressure and a waveform of the pressure pulse wave oscillation signals in the cuff; (III) averaging the waveform of the pressure pulse wave oscillation signals and calibrating the averaged waveform; (IV) analyzing the calibrated pressure pulse wave oscillation signal waveform to obtain a plurality of predicting variables; and (V) obtaining an estimate of the central aortic pulse pressure by values of predicting variables in step (IV) and the equation in step (I).

Abstract: The present disclosure relates to methods, devices, and systems for measuring a blood analyte, such as glucose. The disclosure relates more specifically to the use in such methods, devices, and systems of one or more accelerometers to aid in the collection of data, operation of the device, filtering, and other uses. In some embodiments, the accelerometers are three-dimensional accelerometers. An accelerometer can be used in conjunction with analyte monitoring that may be performed with infrared, near infrared, or other wavelength spectroscopy. The accelerometer may allow a monitoring instrument to expect noisy measurement data, indicate positioning of a measurement site for improved expected results, indicate position of the instrument, or help the user properly place or control the instrument.

Abstract: The present invention relates to a physical fitness test which is easy to do, easy to monitor and is easily self correcting. It involves taking a push, pull, core, and cardio test that is easy to do but can be measured for like age and gender individuals.

Abstract: A patient monitoring system can display one or more configurable health monitors on a configurable user interface. The health indicators are configured to display a physiological signal from a patient. The patient monitoring system can calculate ranges of values for the health indicator that correspond to a status of the patient. The health indicators can display different outputs based on the value of the physiological signal.

Abstract: Provided is a method of using a light sensor earphone to control an electronic device. The method includes: a light sensor earphone detecting light intensity of an ear close side and light intensity of an ear outer side according to a received light signal; comparing the light intensity of the close ear side with the light intensity of the ear outer side, and generating an electric signal corresponding to a current mode of an electronic device according to a comparison result; and sending the electric signal to the electronic device, for the electronic device to control a corresponding function in the current mode according to the electric signal. A light sensor earphone is also provided. By means of the technical solutions, the light sensor earphone is utilized to intelligently control corresponding functions of the electronic device so as to simplify operation.

Abstract: A monitoring system has biomechanical sensors, physiological sensors and a controller which receive sensory inputs from the sensors to provide output signals for the output device, and it detects from the sensory inputs risk of a syncopal event The bio-mechanical sensors include sensors arranged to allow the processor to detect a user postures and posture transitions. The processor operates a finite state machine, in which there is a state corresponding to each of a plurality of user physical postures and to each of a plurality of transitions between said postures, and the processor determines a relevant state depending on the sensory inputs. A device output may be muscle stimulation to prevent syncope, and there are stimulation permissions associated with the finite state machine states.

Abstract: One innovative aspect is directed to heartrate data collection. In some implementations, a circuit includes a light detector for generating a detected signal based on received light. The circuit includes a switching circuit configured to receive a first signal based on the detected signal and to switch among a first and a second configuration. In some implementations, the circuit includes a first and a second sampling circuit for sampling a value of the first signal when the switching circuit is in the first configuration and second configurations, respectively. In some implementations, the circuit includes an ambient light cancellation circuit for countering a first component of the first signal while the first switching circuit is in the first configuration. In some implementations, the circuit includes an adjustable gain circuit for adjusting a gain of the first signal while the first switching circuit is in the first configuration.

Abstract: In accordance with embodiments of the present disclosure, a ballistocardiogram (BCG) sensor is used to detect heart and vascular characteristics of a user, and provide a BCG output indicative of the detected cardiovascular characteristics. The BCG output can be used for various purposes, such as detecting arterial aging. Secondary sensors can be used in conjunction with the BCG and can be used to determine the central arterial blood pressure, when used in conjunction with a peripheral blood pressure measurement.

Abstract: An image display apparatus includes a display section (display unit) that displays an image, an information acquisition section that acquires predominance levels of sympathetic nerves and parasympathetic nerves and an activity magnitude of the autonomic nerves based on the biological information, an image generation section that generates the biological state image in which a figure having a size according to the acquired activity magnitude of the autonomic nerves is set along a first axis, along one side of which the predominance level of the sympathetic nerves is set with respect to a reference point and along the other side of which the predominance level of the parasympathetic nerves is set with respect to the reference point, in a position according to the acquired predominance levels of the sympathetic nerves and the parasympathetic nerves.

Abstract: Characteristics of a user's heart are detected. In accordance with an example embodiment, a ballistocardiogram (BCG) sensor is used to detect heart characteristics of a user, and provide a BCG output indicative of the detected heart characteristics. The BCG output is further processed using data from one or more additional sensors, such as to reduce noise and/or otherwise process the BCG signal to characterize the user's heart function.

Abstract: A system (202) generates patient alarms using a stepped alarm scheme. The system (202) includes one or more processors (220) programmed to receive physiological scores and/or physiological parameter values; compare the physiological scores and/or the physiological parameter values to a plurality of alarm levels; in response to a physiological score and/or physiological parameter value falling within an uninhibited zone of the alarm levels, issue an alarm; and set a first inhibition period for the uninhibited alarm level after issuing the alarm.

Abstract: An ABPI measurement system includes a cuff for each ankle and a cuff for each arm of a patient. Each cuff has first and second chambers. The four cuffs are applied to each limb (or finger or toe), each chamber is inflated simultaneously to a pressure until a Pneumo Arterial Plethysmography (PAPG) signal related to the arterial flow in the limb is detected at the chambers. The second chambers are then simultaneously inflated until the PAPG signals are extinguished in each limb, the inflation of the second chambers continuing for 10 mmHg to 20 mmHg above the extinguishing pressure. The second chambers are then deflated and the pressure in the second chamber at which the PAPG signal returns in the first chamber is recorded for each limb and this value of the pressure is used to calculate the ABPI. The ABPI is displayed or sent to a remote site.

Abstract: The various embodiments herein relate to systems and methods for controlling the operation of a pulsatile heart assist device in a patient. The systems and methods include utilizing sounds and electrical signals produced by the heart to control the operation of the heart assist device.

Abstract: User interfaces for medical perfusion systems that provide oxygenation, filleting, and recirculation of blood in connection with various medical procedures are provided. In particular, methods of displaying and communicating a desired target flow rate and cardiac index during cardiopulmonary bypass surgeries are provided.

Abstract: Characteristics of a user's heart are detected. In accordance with an example embodiment, a ballistocardiogram (BCG) sensor is used to detect heart characteristics of a user, and provide a BCG output indicative of the detected heart characteristics. The BCG output is further processed using data from one or more additional sensors, such as to reduce noise and/or otherwise process the BCG signal to characterize the user's heart function.

Abstract: A biometric information processing device includes a heart rate detection unit, a relative heart rate calculation unit, a relative oxygen intake calculation unit, an oxygen intake estimation unit and a calorie expenditure calculation unit. The relative heart rate calculation unit calculates a relative heart rate obtained from a first difference over a second difference, the first difference being by subtracting a resting heart rate of the subject from the heart rate, the second difference being by subtracting the resting heart rate from a maximum heart rate. The relative oxygen intake calculation unit calculates a relative oxygen intake based on the relative heart rate. The oxygen intake estimation unit estimates the oxygen intake from the relative oxygen intake. The calorie expenditure calculation unit calculates calorie expenditure based on the oxygen intake.

Abstract: The present invention discloses a method and signal processing device (620) for analyzing a ballistocardiogram (BCG). The actual energy content of the cardiac part of the BCG in a predefined time window is determined and compared with a reference value. A difference between the actual energy content and the reference energy content exceeding a predefined threshold is indicative of the presence of an arrhythmia in the evaluated part of the BCG because the force exerted by an arrhythmic ventricular contraction, if at all present, is typically substantially smaller than the force exerted by a ventricular contraction of a regular heartbeat. This insight facilitates a more accurate detection of the presence of arrhythmias in a BCG compared to BCG detection schemes based on a heart rate analysis.

Abstract: A medical system provides navigation assistance to a surgeon so that the surgeon may navigate a flexible medical device through linked passages of an anatomical structure to a target in or adjacent to the anatomical structure. As the medical device moves through the linked passages, images are captured by an image capturing element at its distal end and pose and shape information for the medical device are received from sensors disposed in the medical device. A 4-D computer model of the anatomical structure is registered to the medical device using one or both of 4-D shape registration and virtual camera registration so that the captured image and a virtual image generated from the perspective of a virtual camera are registered to each other and displayed while providing an indication of a navigational path to the target.

Abstract: An embodiment includes a cardiovascular surgical apparatus comprising: a sleeve including a distal sleeve end, a proximal sleeve end, and a sleeve long axis extending from the distal sleeve end to the proximal sleeve end; a post including a distal post end and a proximal post end; a first projection member, coupled to the distal sleeve end, including a first projection member main body and a first projection member retention body; a second projection member coupled to the proximal sleeve end; wherein (a) the post telescopes distally from within the sleeve and away from the distal sleeve end; (b) at least one of the first and second projection members rotates at least 45 degrees with respect to another of the first and second projection members; and (c) the first projection member retention body includes a long axis generally parallel to the sleeve long axis. Other embodiments are described herein.

Abstract: A balloon catheter adapted for cooperating with an endoscope, the balloon catheter including a catheter shaft, a balloon located at a catheter shaft tip, wherein the catheter shaft includes visual markers designed for determining the length of a stenosis in a bodily structure.

Abstract: An intravascular sensor delivery device can have a sensor that is used to measure a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used in combination with a medical guidewire carrying another sensor also configured to measure a physiological parameter of the patient, such as blood pressure. Data generated from the intravascular sensor delivery device sensor and the guidewire sensor can be used to determine a characteristic of interest for the vascular structure under investigation. For example, the data can be used to calculate a pressure distal to pressure proximal ratio across a stenotic lesion in order to assess the severity of the lesion.

Abstract: A therapeutic or diagnostic instrument includes first and second shaped wire members and that can be simultaneously inserted into a catheter tube and has predetermined bending elasticity, in which the first and second shaped wire members and are adapted to respectively have first and second curving parts that curve in a natural state, and when inserted into the catheter tube, curve the catheter tube at two desired positions correspondingly with the first and second curving parts.

Abstract: Systems and methods using a database of physiological information for the design, development, testing and use of therapeutics. In one aspect, the physiological information can include at least one of: hemodynamic monitoring information, pulmonary arterial pressure, cardiac output, heart rate, respiratory rate, peripheral vascular resistance, total peripheral resistance or dicrotic notch information. Optionally, the cardiovascular physiology information can include ambulatory physiological information.

Abstract: Disclosed herein is a system for monitoring a patient that includes a cuff configured to inflate to at least partially occlude an artery of the patient and a cuff controller configured to control inflation and deflation of the cuff. The system also includes a sensor configured to receive a signal associated with the at least partially occluded artery and generate an output signal based on the received signal. Also included is a signal analysis module configured to receive the output signal and determine a first hemodynamic parameter based on a first set of data obtained during inflation of the cuff and a second set of data obtained during deflation of the cuff.

Abstract: An embodiment generally relates to systems and methods for estimating heart rates of individuals using non-contact imaging. A processing module can process multi-spectral video images of individuals and detect skin blobs within different images of the multi-spectral video images. The skin blobs can be converted into time series signals and processed with a band pass filter. Further, the time series signals can be processed to separate pulse signals from unnecessary signals. The heart rate of the individual can be estimated according to the resulting time series signal processing.

Abstract: A biometric monitoring device is used to determine a user's heart rate by using a heartbeat waveform sensor and a motion detecting sensor. In some embodiments, the device collects collecting concurrent output data from the heartbeat waveform sensor and output data from the motion detecting sensor, detects a periodic component of the output data from the motion detecting sensor, and uses the periodic component of the output data from the motion detecting sensor to remove a corresponding periodic component from the output data from the heartbeat waveform sensor. From this result, the device may determine and present the user's heart rate.

Abstract: A vital signs monitor system is integrated with personal protective equipment (“PPE”) so that upon wearing the PPE, the monitor is placed in an operational position to monitor a vital sign. In one embodiment, the vital signs sensor comprises a thermal sensor located at a mouth guard to automatically make operational contact with tissue under the tongue when the mouth guard is worn. A second vital signs monitor comprising reflective pulse oximetry devices senses oxygen saturation and heart rate. Vital signs data are communicated to an RF module located in an associated helmet for transmission to a remote location. A gateway at that remote location receives the transmitted vital signs data and forwards that data to a data collection, organization, and access system that is programmed to make the vital signs data available over the Internet.

Abstract: System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities. The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a nerve bundle, or the surface of the heart. Such direct, conformal contact increases accuracy of measurement and delivery of therapy.

Abstract: A biometric monitoring device is used to determine a user's heart rate by using a heartbeat waveform sensor and a motion detecting sensor. In some embodiments, the device collects collecting concurrent output data from the heartbeat waveform sensor and output data from the motion detecting sensor, detects a periodic component of the output data from the motion detecting sensor, and uses the periodic component of the output data from the motion detecting sensor to remove a corresponding periodic component from the output data from the heartbeat waveform sensor. From this result, the device may determine and present the user's heart rate.

Abstract: The presence of a cardiac pulse in a patient is determined by evaluating physiological signals in the patient. In one embodiment, a medical device evaluates optical characteristics of light transmitted into a patient to ascertain physiological signals, such as pulsatile changes in general blood volume proximate a light detector module. Using these features, the medical device determines whether a cardiac pulse is present in the patient. The medical device may also be configured to report whether the patient is in a VF, VT, asystole, or PEA condition, in addition to being in a pulseless condition, and prompt different therapies, such as chest compressions, rescue breathing, defibrillation, and PEA-specific electrotherapy, depending on the analysis of the physiological signals. Auto-capture of a cardiac pulse using pacing stimuli is further provided.

Abstract: Embodiments are directed towards authenticating users using biometric devices. The biometric device may be arranged to capture one or more biometric feature of a user that may be wearing the biometric device such as biometric features that correspond to an electrocardiogram of the user. The user of the biometric device may be authenticated based on one or more biometric features, or a combination thereof. Authenticating the user of the biometric device, may include communicating information that includes biometric features to an authorized authentication device (AAD). When the user is authenticated, the biometric device may be preauthorized for the user. When the preauthorized biometric device senses at least one access point, an authorization signal may be provided to the access point. If the preauthorized biometric device is removed from the user, the biometric device is deauthorized, disabling access to access points by the user.

Abstract: Clothing with an integrated heart rate monitoring device for monitoring the vital signs of a user is disclosed herein. The monitoring device preferably comprises an optical sensor, an accelerometer and processor. The optical sensor preferably comprises a photodetector and a plurality of light emitting diodes. A sensor signal from the optical sensor is processed to generate a real-time vital sign for a user.

Abstract: There is provided herein a breath sampling device comprising a controller adapted to initiate a signal to trigger a valve functionally associated with a breath sampling tube upon said controller receiving a signal indicating a blockage in the breath sampling tube. The valve is adapted to facilitate an increase of pressure within the breath sampling tube between the blockage and a pump functionally associated with the breath sampling tube. There is further provided herein an airway adapter comprising a restrictor located in proximity to a connection point between the airway adapter and a breath sampling tube, wherein the restrictor may be adapted to reduce the flow rate of liquids entering the breath sampling tube.

Abstract: A method for predicting an increased risk for a complication in a patient subjected to mechanical circulatory support. The method includes continuously, or within given intervals, registering a acoustic intensity verses frequency curve from the mechanical circulatory support. Repeated sound intensity verses frequency curves are registered from a patient to obtain a mean curve for the patient. New sound intensity-frequency curves are repeatedly obtained and compared with the mean curve. Significant deviations between a new sound intensity-frequency curve and the mean curve are detected and indicate an increased risk for a complication event.

Abstract: The present invention is directed in various methods, devices and systems relating to systems and methods for measuring and calculating a biological conduit's, e.g., a blood vessel, inner diameter, the opposition force of the conduit's wall on an expanding balloon disposed therein and the conduit and/or lesion compliance to the expanding balloon.

Abstract: A system and method for evaluating a circulatory function of an individual includes at least one connection configured to receive signals indicative of functional data relating to at least one functional parameter of the cardiovascular system of the subject and to at least two disparate locations on the subject. A processor is coupled to the at least, one connection and configured to receive the functional data from the at least one connection. The processor is also configured to compare the functional data to identify variations that deviate from an expected delay associated with the disparate locations and provide an assessment of the cardiovascular system function based on the comparison of the functional data.

Abstract: Method and apparatus are provided for computing signals related to cardiac output from physiologic input signals related to circulatory pressures or flows. Method and apparatus are provided for constructing a transforming filter and applying said filter to the physiologic input signals in order to obtain a signal proportional to phasic cardiac output or time-averaged cardiac output. This invention provides a means for real-time monitoring of cardiac output and stroke volume which is of great clinical importance but not otherwise feasible by present techniques.

Abstract: Methods and apparatus combine patient measurement data with demographic or physiological data of the patient to determine an output that can be used to diagnose and treat the patient. A customized output can be determined based the demographics of the patient, physiological data of the patient, and data of a population of patients. In another aspect, patient measurement data is used to predict an impending cardiac event, such as acute decompensated heart failure. At least one personalized value is determined for the patient, and a patient event prediction output is generated based at least in part on the personalized value and the measurement data. For example, bioimpedance data may be used to establish a baseline impedance specific to the patient, and the patient event prediction output generated based in part on the relationship of ongoing impedance measurements to the baseline impedance. Multivariate prediction models may enhance prediction accuracy.

Abstract: A system and method for providing balanced, automated regulation of a patient's physiological condition by monitoring at least one physiological parameter and, optionally, monitoring and controlling additional physiological parameters, is disclosed. The system includes a physiological parameter monitor, an intelligent control device and a multi-channel delivery device for providing controlled intravenous delivery of at least two medications that affect the physiological condition being controlled. Control logic in the intelligent control device is derived by an algorithm based on model predictive control. The control logic includes mathematically modeled systems, empirical data systems or a combination thereof. The system of the present invention is optionally included in a networked system to provide centralized data storage and archival of system information as well as data export and query capabilities that can be used for patient file management, health care facility management and medical research.

Abstract: A method for establishing a connection between a first electronic computing device and a second electronic computing device includes moving the second electronic computing device so that it is proximal to the first electronic computing device. When the first electronic computing device detects the proximity of the first electronic computing device relative to the second electronic computing device, a radio on the first electronic device is set to a connectable and discoverable state. A wireless connection is automatically established between the first electronic computing device and the second electronic computing device. Data is transmitted between the first electronic computing device and the second electronic computing device.

Abstract: Some embodiments provide a wearable fitness monitoring device including a motion sensor and a photoplethysmographic (PPG) sensor. The PPG sensor includes (i) a periodic light source, (ii) a photo detector, and (iii) circuitry determining a user's heart rate from an output of the photo detector. Some embodiments provide methods for operating a heart rate monitor of a wearable fitness monitoring device to measure one or more characteristics of a heartbeat waveform. Some embodiments provide methods for operating the wearable fitness monitoring device in a low power state when the device determines that the device is not worn by a user. Some embodiments provide methods for operating the wearable fitness monitoring device in a normal power state when the device determines that the device is worn by a user. Some embodiments provide methods for using response characteristics of the user's skin to adjust a gain and/or light emission intensity of the heart rate monitor.

Abstract: Embodiments of the invention pertain to kiosks and home kits capable of providing authenticated health information for purposes of privacy, rewards, or incentives. In an embodiment of the invention, biometric measurement devices coupled with a communications infrastructure implement a system of secure information exchange and enhanced data security. In an embodiment of the invention, a user's communications device such as a cell phone is wirelessly connected through or by the machine to a call center or other responder to allow for consultation when appropriate. In an embodiment of the invention, a security/verification system is built into the kiosk, so as to be able to verify a user's identity.