Abstract: A closable male luer connector is provided in which an inner portion within the spigot of the connector is movable from a sealing position to an open position on connection of the connector to a female luer connector wherein the movement of the inner portion may be caused by, for example, action of the female connector on a projecting arm or a screw thread arrangement.

Abstract: A disposable injector with a housing (10) in which are arranged at least one mechanical spring energy store (50), at least one cylinder-piston unit that can be filled at least temporarily with an active substance, at least one piston actuation plunger (60) and at least one triggering unit (80). The spring energy store comprises at least one pre-loaded spring element. The spring-loaded piston actuation plunger has at least one traction rod (61) which can be moved transversely, at least in certain regions, and by means of a supporting portion supports the tensioned spring energy store on at least one resting surface (37) of the housing. An actuatable triggering slide device (82) unlocks the disposable injector and releases the supporting portion to allow it to move away from the resting surface.

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible, pre-filled drug container that contains the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

Abstract: The present invention relates to a medical delivery device comprising a generally elongated housing, a container containing medicament to be delivered, a drive means capable of acting on said container for expelling said medicament, wherein said drive means comprises at least two force spring means arranged between a fixed part of the device and a movable part of the device.

Abstract: A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

Abstract: A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

Abstract: A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

Abstract: A basal hub for attaching to an infusion base is disclosed. The hub includes a fluid reservoir and pressure actuating device. A septum portion of the reservoir is configured to be opened by a flow cannula that is in fluid communication with an infusion cannula of the infusion base, when the basal hub is attached to the infusion base. The pressure actuating device applies pressure to the fluid reservoir, such that when the septum portion of the fluid reservoir is pierced by the by the flow cannula, liquid stored in the fluid reservoir is released from the fluid reservoir into the infusion cannula of the infusion base via the flow cannula. The basal hub is configured to deliver a basal dose of insulin during periods of inactivity, such as during sleep time.

Abstract: An infusion system comprises a disposable wearable infusion device having a body arranged to be adhered to a patient's skin and a reservoir for holding a liquid medicament to be infused into the patient through a cannula extending from the device body to beneath the patient's skin. The system further includes a cannula driver arranged to be detachably joined with the infusion device and including the cannula. The cannula driver is arranged to drive the cannula into a deployed position extending from the device body to beneath the patient's skin. The cannula driver includes a release mechanism that separates the cannula driver from the infusion device after the cannula is in the deployed position.

Abstract: Various methods and devices for driving fluid from a syringe are provided. In one exemplary embodiment, a syringe driver is provided having a frame that is adapted to seat a syringe, a driver that is slidably disposed within the frame and that is adapted to seat a plunger of a syringe, and a puller that is slidably disposed within the frame and that has a latch formed thereon for mating to an engagement element on the frame. The device can also include a force-delivery element, such as a constant force spring, that is coupled to and extends between the driver and the puller.

Abstract: A wearable infusion device comprises a reservoir that holds a liquid medicament, an outlet port that delivers the liquid medicament to a patient, a pump that displaces a volume of the liquid medicament to the outlet port when actuated, and a control that actuates the pump. A lock-out disables the device when a predefined amount of medicament has been delivered to the outlet.

Abstract: A wearable infusion device comprises a reservoir that holds a liquid medicament, an outlet port that delivers the liquid medicament to a patient, a pump that delivers a volume of the liquid medicament from the reservoir to the outlet when actuated, and a tactile indicator representing the volume of the liquid medicament delivered to the outlet with each actuation of the pump.

Abstract: An infusion medium delivery system, device and method for delivering an infusion medium to a patient-user, includes a needle inserter device and method for inserting a needle and/or cannula into a patient-user. The needle inserter device and method operate to insert a needle and cannula into a patient-user's skin and automatically withdraw the needle from the patient-user, leaving the cannula in place and in fluid flow communication with a reservoir. The delivery device may include a base portion and a durable portion connectable to the base portion, and wherein the base portion can be separated from the durable portion and disposed of after one or more specified number of uses. The base portion supports the reservoir and the needle inserter device, while the durable portion supports a drive device.

Abstract: There is provided a venting system for enteral feeding having a reflux bag in fluid communication with an enteral feeding site on a patient. The bag has a vent that relieves enteral pressure from the patient and is located within a bellows that compresses the refluc bag after the vent relieves. The system does not rely on gravity to urge the liquid in the reflux bag back to the patient so it may be used by sleeping patients who change positions. It may also be placed in a backpack so that the patient may be freed from having to remain seated or prone for long periods of time and can instead lead a more normal lifestyle.

Abstract: An infusion medium delivery system, device and method for delivering an infusion medium to a patient-user, includes a needle inserter device and method for inserting a needle and/or cannula into a patient-user to convey the infusion medium to the patient-user. The needle inserter device and method operate to insert a needle and cannula into a patient-user's skin and automatically withdraw the needle from the patient-user, leaving the cannula in place and in fluid flow communication with a reservoir. The delivery device may include a base portion and a durable portion connectable to the base portion, and wherein the base portion can be separated from the durable portion and disposed of after one or more specified number of uses. The base portion supports the reservoir and the needle inserter device, while the durable portion supports a drive device for selectively driving the infusion medium out of the reservoir and into the needle and/or cannula.

Abstract: A disposable injector with a housing (10) in which are arranged at least one mechanical spring energy store (50), at least one cylinder-piston unit that can be filled at least temporarily with an active substance, at least one piston actuation plunger (60) and at least one triggering unit (80). The spring energy store comprises at least one pre-loaded spring element. The spring-loaded piston actuation plunger has at least one traction rod (61) which can be moved transversely, at least in certain regions, and by means of a supporting portion supports the tensioned spring energy store on at least one resting surface (37) of the housing. An actuatable triggering slide device (82) unlocks the disposable injector and releases the supporting portion to allow it to move away from the resting surface.

Abstract: An injection device includes a multi-use drive assembly 10 and a single use disposable syringe assembly 12 releasably connected thereto. The syringe assembly includes a syringe 18 and a shield 26 mounted for telescopic movement. The drive assembly 10 is operable to extend the syringe 18 relative to the shield 26 and then to express a dose. Continued forward drive movement extends the shield 26 to re-cover the syringe needle 22 and then ejects the spent syringe assembly 12 in a safe (shrouded) condition.

Abstract: The present invention relates to a device for delivering medicament, comprising a container (12) arranged to contain medicament, which container further comprises an opening arranged to expel medicament from the container, pressure means (16, 18) arranged to exert pressure on the medicament inside the container (12) for expelling a certain predetermined quantity of the medicament through the opening, driving means (26, 42) for driving said pressure means (16, 18), and activation means (46) for activating said driving means (26, 42) wherein said device comprises pressure release means (20) which are adapted, arranged and designed such that, when the predetermined dose has been expelled through the opening, the pressure on the medicament is released.

Abstract: A standard dental syringe is made up of an outer cylinder with a plunger at one end, and a carpule which contains liquid medication to be injected into a patient is replaceably positioned within the barrel and includes a needle slidably mounted at one end of the carpule in communication with the fluid medication which is contained in a fluid chamber sealed off at each end by a plug so that when the plunger is advanced into engagement with a first plug at one end of the carpule the liquid medication is delivered through the needle and upon completion of the plunger stroke, a barbed extension of the slidable first plug member will move into engagement with the needle-retaining second plug member so that upon retraction of the plunger the needle-retaining plug member will be retracted along with the slidable first plug member.

Abstract: An auto-injection syringe is provided that includes an injection assembly and a retraction assembly operatively securable to the injection assembly. The retraction assembly includes a hypodermic needle having a needle hub, an end cap having a lower seal through which a portion of the hypodermic needle can pass, a retraction spring disposed between the needle hub and the end cap and maintained in a partially compressed condition therebetween, an upper seal urged against a facially sealing surface of the retraction assembly by the force of the retraction spring on the needle hub so that a sealed area is defined between the upper and lower seals, and a vent device in fluid communication with the sealed area for pressure equalization between the sealed area and an exterior of the retraction assembly.

Abstract: The invention refers to an interlock mechanism for restricting a rotational movement of a rotatable component (1) of a drug delivery device (10) and to a method for controlling the rotational movement of the rotatable component (1).

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible, pre-filled drug container that contains the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

Abstract: The invention refers to a motor mechanism (6) for a drug delivery device (1), comprising a storage drum (8) and a torque drum (9) arranged close to each other and a strip (7) of spring sheet metal having two ends, each end attached to one of the drums (8, 9), wherein the strip (7) of spring sheet metal is coiled on the storage drum (8) in a relaxed state, wherein the motor mechanism (6) is chargeable by rotating the torque drum (9) thereby coiling the strip (7) of spring sheet metal onto the torque drum (9) and bending the strip (7) of spring sheet metal the other way round than in the relaxed state thus arriving in a charged state with the strip (7) of spring sheet metal tending to re-coil onto the storage drum (8) thereby generating a torque.

Abstract: A dispensing device for dispensing medicaments to a patient that includes first, second and third stand-alone, inter-connectable assemblies. The first of these assemblies comprises a fluid delivery and control assembly that includes a novel flow control assembly that functions to control the flow of medicinal fluid from the fluid reservoirs of the first and second assemblies of the invention toward the patient via a plurality of fluid flow control passageways. The second and third stand-alone reservoir defining components, which are interconnected with the fluid and delivery control component, each include an integrally formed, hermetically sealed collapsible container and a spring for controllably collapsing the container.

Abstract: The present invention relates to medicament delivery device comprising a generally tubular distal housing part (19); a generally tubular medicament container holder (16); a medicament container (18); a plunger rod (32); resilient force; an actuation means (34) comprising flexible locking means and an activation button; a release means (40); and a resilient means (60) characterized in that said plunger rod comprises a number of stop engagements (38) arranged on its outer circumferential surface and arranged to co-act with corresponding stop engagements (37) on the flexible locking means, such that when said activation button is proximally depressed said stop engagement (37) on said flexible locking means come out of contact from one stop engagement (38) of the plunger rod; and such that when said activation button (48) is released, said resilient means (60) forces the activation button and thereby the flexible locking means to move distally such that said stop engagements (37) on said flexible locking means co

Abstract: An injection apparatus (2) has a carrier housing (4), into which an injection device (8) having at least one injection fluid container (10) that can be pressed out can be inserted, and an actuating apparatus (12) which can be driven along an injection direction (R) in order to activate the injection device (8) and which can be acted on for performing at least one pricking stroke and one injection stroke by a mechanical energy storage unit (20) and an electrical transport unit (26). The invention provides for the actuating apparatus (12) to be driven in the injection direction (R) by the driving force of a mechanical energy storage unit (20) and for the electrical transport unit (26) to form a speed limiter which acts counter to the driving force during an injection, in order to limit a stroke speed attained via the energy storage unit.

Abstract: A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the apparatus reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the apparatus reservoir to the patient.

Abstract: A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as analgesics and like medicinal agents from the device reservoir which is provided in the form of a novel bellows-type assembly. The fluid dispenser includes a unique stored energy mechanism that provides the force necessary to continuously and substantially uniformly expel fluid from the device reservoir. The device also includes a novel adjustable flow rate control assembly that is disposed intermediate the fluid reservoir outlet and the outlet port of the device for precisely controlling the rate of fluid flow from the outlet port toward the patient.

Abstract: Devices and methods for delivering a fluid to a patient are disclosed herein. In one embodiment, a delivery system includes a reservoir for containing a fluid and a fluid communicator in fluid communication with the reservoir. An electrochemical actuator is coupled to the reservoir and configured to exert a force on the reservoir upon actuation such that fluid within the reservoir is communicated through the fluid communicator. The actuator includes a first end that is constrained and a second end that is not constrained. The actuator is configured to bend at a location along a length of the actuator when actuated such that the second end of the actuator is displaced in a direction toward the fluid reservoir. The actuator can be an electrochemical actuator. The apparatus can further include a transfer structure disposed between the actuator and the reservoir configured to contact the reservoir upon actuation of the actuator.

Abstract: A dual reservoir fluid dispensing apparatus for use in controllably dispensing fluid medicaments, such as antibiotics, analgesics and like medicinal agents from either or both of the device reservoirs. The fluid dispensing apparatus includes novel fill means for selectively filling each of the reservoirs with the same or different medicaments that are to be dispensed to the patient. Stored energy sources are provided in the form of a pair of constant force spring members of novel design that provide the force necessary to continuously and substantially uniformly expel fluid from the reservoirs. The apparatus also includes novel adjustable flow rate assemblies that are disposed intermediate the outlet port of the fluid reservoirs and the outlet port of the device for precisely controlling the rate of fluid flow from the outlet port toward the patient.

Abstract: A body-insertable apparatus including a balloon for storing a medical fluid in a capsule-like casing, and an injection needle including an elastic membrane. The body-insertable apparatus discharges the medical fluid due to contraction of the balloon, applies a discharge pressure of the medical fluid to the elastic membrane to expand the elastic membrane, and projects the injection needle from the casing due to the expansion of the elastic membrane. Further, the body-insertable apparatus has a channel forming unit for forming a channel connecting to the balloon and a channel connecting to the injection needle, and a communication adjusting mechanism. The communication adjusting mechanism adjusts a communicated state between the channels and, thereby controlling the start of medical-fluid discharge operation by the balloon.

Abstract: A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the apparatus reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the apparatus reservoir to the patient.

Abstract: A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed.

Abstract: A disposable syringe assembly for use in an autoinjector device, or manually includes a syringe housing which receives the syringe barrel and which is restrained against longitudinal movement with respect thereto, a shield portion mounted for generally telescopic movement relative to the syringe housing between a retracted position and an extended position in which in use it shields the syringe needle, and a lock out arrangement activated as the shield moves towards its extended position to prevent retraction therefrom. When fitted in an autoinjector the autoinjector may include drive mechanism for moving the shield portion to its locked out extended position, whereby, on completion of an injection operation, the disposable syringe assembly may be removed from the autoinjector in a shielded condition for subsequent disposal.

Abstract: Systems, devices, and methods are provided for dispensing material from a container. Devices can include driving means for providing one or more forces, and actuator means for activating the driving means whereby the driving means causes material to be dispensed from the container.

Abstract: Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Some embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. The device comprises a capsule sized to be swallowed and pass through the intestinal tract. The capsule can include at least one guide tube, one or more tissue penetrating members positioned in the guide tube, a delivery member, an actuating mechanism and a release element. The release element degrades upon exposure to various conditions in the intestine so as to release and actuate the actuating mechanism. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

Abstract: A medication delivery device includes a housing, a door coupled to the housing and moveable between a closed position and an open position. The door permits insertion of a medication container, containing liquid medication, into the housing in the open position. A door opening mechanism is coupled to the door. A push member is axially moveable between a retracted position and a non-retracted position and located external to the medication container. The push member enters the medication container and pushes the liquid medication out of the medication container. A lock mechanism is coupled to the door opening mechanism and prevents opening of the door when the push member is in the non-retracted position inside the medication container, wherein the lock mechanism automatically unlocks the door opening mechanism when the push member is in the retracted position.

Abstract: An autoinjection device includes a main body 12 in the front end of which is slideably mounted a drawer or front body portion 14. The drawer can be opened to remove or insert a syringe. Closing the drawer whilst pressing a multifunction button 22 primes the drive mechanism 54, 58 by latching it against trigger latch 66. Pressing the button 22 again whilst urging the front end causes the drawer to release the trigger latch 66. After the injection the drawer shrouds the used needle and can be released only by pressing the button 22.

Abstract: An infusion media delivery device includes a housing having a base adapted to be secured to a user's skin. An infusion media reservoir is supported by the housing. A moveable hollow needle is selectively engageable with the reservoir to communicate infusion media from the reservoir. The needle is supported for movement relative to the housing base between a first position and a second position. The needle is spaced apart from a user's skin when in the first position and the base is secured to the user's skin, and the needle is arranged to pierce the user's skin when in the second position and the base is secured to the user's skin.

Abstract: The present invention relates to a method of operating an injection device, which device comprises a medicament cartridge and a needle attached to said cartridge, means for automatic penetration of needle, injection of medicament and withdrawal of needle, comprising the steps of initiating a penetration sequence, followed by an injection sequence and followed by a withdrawal sequence, wherein a previous sequence triggers a subsequent sequence, and wherein the subsequent sequence is triggered before the previous sequence has ended.

Abstract: A device for administering a fluid product including a housing, a conveying device for the product, a coupling element provided for the drive of the conveying device and which can be rotated about a rotational axis, a first blocking element connected in a rotationally secure manner to the coupling element, a second blocking element detachably engageable with the first blocking element thereby preventing a rotational movement thereof in the drive direction and enabling said rotational movement to take place in the counter dosing direction, a torsion spring connected to the coupling element such that it is stressed by the rotational movement when the blocking elements are engaged in a blocked position and drives the coupling element in a rotary manner after the blocking position is released, and a release element coupled to at least one of the blocking elements such that a release movement of the release element displaces at least one of the blocking elements from the blocked position, the release element also

Abstract: An administering device for a fluid product includes a product receptacle that accommodates the product to be administered, a fluid reservoir for a driving fluid, a driving means, a product chamber, and a fluid connection. The product receptacle includes an opening at a forward end and a product stopper at a rear end. The driving means acts upon the fluid reservoir, the pressure chamber adjoins the product stopper while the fluid connection is located between the fluid reservoir and the pressure chamber, and the driving means acts upon the fluid reservoir in such a way that the pressure chamber is impinged upon by pressure which affects the product stopper and the product is discharged from the product receptacle.

Abstract: A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug deliver pump.

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible drug container that can be filled in the field with the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible, pre-filled drug container that contains the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

Abstract: An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed.

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible drug container that can be filled in the field with the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

Abstract: Various methods and devices for driving fluid from a syringe are provided. In one exemplary embodiment, a syringe driver is provided having a frame that is adapted to seat a syringe, a driver that is slidably disposed within the frame and that is adapted to seat a plunger of a syringe, and a puller that is slidably disposed within the frame and that has a latch formed thereon for mating to an engagement element on the frame. The device can also include a force-delivery element, such as a constant force spring, that is coupled to and extends between the driver and the puller.

Abstract: A portable drug delivery system (10) includes a remote unit (14) which serves as a wireless monitor for a drug delivery device (12). Programming of the drug delivery device (12) can be achieved by use of the remote unit (14), but requires tactile intervention by the user with the drug delivery device, thereby avoiding inadvertent or unauthorized changes to the drug delivery settings via the wireless unit. Also disclosed are configurations for receiving and retaining a drug cartridge (42) within a disposable unit (40) of the drug delivery device, and a kit providing user-selectable form factor for the infusion set used with the drug delivery device, allowing the user to select either an integrated infusion set (112) or an external infusion (106) set for each session of use.

Abstract: An autoinjector device comprises a drive housing 10 and a syringe housing 12 which can be disconnected to allow insertion of a syringe. A drive mechanism in the drive housing is cocked by means of a cord 8 connected between the drive housing and the syringe housing. The drive mechanism comprises a drive gear 22 rotatably mounted in the drive housing and acting as a rotary crank connected by a connecting rod 26 to a plunger 28. In use the drive gear 22 is driven by a torsion spring 35 so that the drive mechanism extends the syringe from the syringe housing and expels a dose and then retracts the syringe back into the housing. A firing button 14 releases the drive gear to be driven by the torsion spring but is also engageable as a brake on the rim of the drive gear.