Abstract: An autoinjector comprising an outer housing in which can be mounted a syringe for holding a volume of medicament, the syringe for holding medicament having a needle at one end thereof, a syringe holder for supporting the syringe in an axial position relative to the outer housing, and an intermediate housing at least part of which is located within said outer housing, characterised in that said intermediate housing is provided with a blocking means capable of abutting the syringe or the syringe holder so as to be capable of preventing forward axial movement of the syringe when a forward axial force is applied to said needle before actuation of the autoinjector to deliver an injection, but incapable of preventing forward axial movement of the syringe during actuation of the autoinjector to deliver an injection.

Abstract: A drug-delivery device comprising a drug-reservoir assembly, displacement-generating actuator, and drug administration unit is described, wherein the drug-reservoir assembly comprises at least one flexible wall and a constraining ring, such that the displacement generated by the actuator collapses a flexible wall of the assembly expelling the drug contents of the drug-reservoir towards said drug administration means.

Abstract: A delivery system includes a reservoir, a fluid communicator, and an actuator. The reservoir is configured to contain a fluid and is in fluid communication with the fluid communicator. The actuator includes an unconstrained first end portion, an unconstrained second end portion, and a constrained medial portion therebetween. When the actuator is actuated the medial portion is configured to bend along a bend axis to produce a displacement of the first end portion and the second end portion relative to the medial portion. The bending of the actuator is configured to displace the actuator towards the reservoir to exert a force on the reservoir such that a fluid disposed within the reservoir is communicated through the fluid communicator.

Abstract: A delivery system includes a reservoir configured to contain a fluid and a fluid communicator configured to be placed in fluid communication with the reservoir. A first actuator is coupled to the reservoir and configured to exert a first force on the reservoir upon actuation. A transfer structure disposed between the first actuator and the reservoir is configured to engage the reservoir distribute the first force across a surface of the reservoir. A second actuator is disposed and oriented so that when the first actuator is displaced toward the fluid reservoir, the second actuator moves from a first configuration to a second configuration and exerts a second force on the transfer structure. The combination of the first and second forces collectively urge the transfer structure towards the reservoir such that fluid within the reservoir is communicated through the fluid communicator.

Abstract: A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

Abstract: The present invention relates to a device for automatic injection of a product comprising a container, a needle and a piston. The device includes a housing receiving the container, the container being movable with respect to the housing between an initial position and an insertion position, distally spaced relative to the initial position; a safety shield coupled to the housing and movable with respect thereto between a rest position, an activation position, proximally spaced relative to the rest position, and a safety position, distally spaced with respect to the rest position; biasing feature for causing the movement of the safety shield to the safety position; triggering feature for causing the container to move from its initial position to its insertion position, the triggering feature being releasable by movement of the safety shield to the activation position; and, isolating feature for isolating the safety shield from the biasing feature when the safety shield is moved to its activation position.

Abstract: A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the device reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the device reservoir to the patient.

Abstract: An autoinjector device comprises a drive housing 10 and a syringe housing 12 which can be disconnected to allow insertion of a syringe. A drive mechanism in the drive housing is cocked by means of a cord 8 connected between the drive housing and the syringe housing. The drive mechanism comprises a drive gear 22 rotatably mounted in the drive housing and acting as a rotary crank connected by a connecting rod 26 to a plunger 28. In use the drive gear 22 is driven by a torsion spring 35 so that the drive mechanism extends the syringe from the syringe housing and expels a dose and then retracts the syringe back into the housing. A firing button 14 releases the drive gear to be driven by the torsion spring but is also engageable as a brake on the rim of the drive gear.

Abstract: The invention relates to an injection device (1), which comprises a support housing (2), an activating sleeve (9), a cartridge (3) containing a medicine (14), a first drive unit (4), a safety device (5), a needle arrangement (6), a needle protection element (7) and a second triggerable drive unit (8), whereby the latter moves the needle protection element (7) from the non-effective position into the position covering one needle end (21) of a cannula (20). The support housing (2) is surrounded over most of its longitudinal extension between its distal and proximal end (11, 12) by the activating sleeve (9), whereby the needle protection element (7) with the second drive unit (8) cooperating therewith is arranged radially between the support housing (2) and the activating sleeve (9), as viewed in axial cross section.

Abstract: A disposable injector with a housing (10) in which are arranged at least one mechanical spring energy reservoir (50), at least one cylinder/piston unit (100), at least one piston-actuating ram, and at least one trigger unit. For this purpose, the housing has at least one inverted draw hook, which has at least one support surface respectively in the region of its free end. The spring-loaded piston-actuating plunger rests on the support surface, whereby the contact zone placed between the draw hook and the piston-actuating plunger represents a variable-speed gear pair thrusting the draw hook radially outwards. The locking position of the draw hook is secured by an actuating element positioned in a locked position. The actuating element has a triggering position which effects radially outwards aligned retreat of the draw hook when the piston-actuating plunger is released.

Abstract: A dispensing device for dispensing first and second medicaments to a patient that is made up of first and second stand-alone, interconnectable assemblies. The first of these assemblies comprises a fluid reservoir assembly that houses a fluid reservoir defining component while the second assembly comprises a fluid delivery and control assembly that includes an adding assembly for controllably dispensing the second medicament to the patient, a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the first assembly toward the patient via a plurality of fluid flow control passageways.

Abstract: The invention relates to an injection device for delivering a drug, comprising a housing arranged to receive a drug container and an electrical energy source, wherein a driver is arranged to displace a dose of the drug from the container under load of a drive spring upon release, wherein an electric motor powered by the electrical energy source is arranged for tensioning the drive spring, wherein control means are arranged for controlling the electric motor so as to tension the drive spring when an injection has been performed.

Abstract: A fluid infusion device, for delivery of a medication fluid to the body of a user, includes a housing, a fluid reservoir for the medication fluid, a dosing mechanism, an infusion component, and a mechanical actuator. The fluid reservoir and the dosing mechanism are located in the housing, and the dosing mechanism is coupled to receive the medication fluid from the fluid reservoir. The dosing mechanism has an adjustable fluid chamber that defines a variable dosage volume. The infusion component is coupled to the dosing mechanism to receive the medication fluid from the adjustable fluid chamber. The mechanical actuator is coupled to the dosing mechanism such that operation of the mechanical actuator causes the medication fluid to be expelled from the adjustable fluid chamber to the infusion component.

Abstract: An apparatus includes a housing, a needle, a first energy storage member and a second energy storage member. The needle is movably disposed within the housing and is configured to be to be placed in fluid communication with a medicament container. The needle is configured to move between a first position and a second position. In its first position, the needle is contained within the housing. In its second position, at least a portion of the needle extends from the housing. The first energy storage member is disposed within the housing, and is configured to produce a first force when actuated. The second energy storage member is disposed within the housing, and is configured to be actuated in response to the first force to produce a second force to move the needle from the first needle position to the second needle position.

Abstract: An injector apparatus includes a housing (101, 102) for a cartridge or syringe, a plunger (40) for cooperating in use with the cartridge or syringe to express successive doses, a dose setting arrangement (16, 20) to select a dose volume, and a drive mechanism (22, 24) releasable to advance the plunger in respective predetermined increments of magnitude to express the successive doses. The drive mechanism includes a drive spring (22) for imparting movement directly or indirectly to the plunger (40), and the dose setting arrangement includes a dose setting element (16) moveable in a dose setting routine to define a magnitude of an increment of movement of the plunger for a given dose. The drive mechanism further includes a clutch arrangement (56) operable during the dose setting routine to inhibit forward movement of the plunger and/or to isolate the dose setting element from the force of the drive spring.

Abstract: Devices, methods, and kits for delivering a therapeutic agent to a patient are disclosed herein. In one embodiment, an apparatus comprises a reservoir for containing a fluid, a first actuator, a transfer structure, and a second actuator. The first actuator has a first configuration and a second configuration and is configured to exert a first force on the reservoir when moved from its first configuration to its second configuration such that a first volume of fluid within the reservoir is communicated out of the fluid reservoir. The transfer structure is disposed between the first actuator and the reservoir and has a surface configured to engage the reservoir such that the first force exerted by the first actuator is distributed across a surface of the reservoir engaged by the transfer structure.

Abstract: An infusion pump unit includes a housing sized to allow the pump unit to be carried as a portable unit. The housing contains a controllable pumping system for pumping fluid. The pump actuator is lighter, smaller, quieter and less power consuming.

Abstract: A device for administering an injectable product, including a housing, a displaceably mounted product container accommodated by the housing, a plunger in the container so that it can be displaced in a forward-drive direction in order to dispense the product, a plunger rod acting on the plunger in the forward-drive direction and having a releasable retained position, and a spring acting on the plunger rod in the forward-drive direction, the plunger rod releasably held in the retained position in a retaining engagement against the force of the spring, wherein the spring projects into the container in the retained position.

Abstract: An injector device includes an injector body that receives a syringe; and an injection assembly being configured to dispense medicament from the syringe in a dispensation step. Certain types of injector devices include a sudden completion indicator that indicates when the injection is completed. Certain types of injector devices are configured to dispense two different medicament formulations having different viscosities from syringes without making any changes to the injector devices other than to switch out the syringes. Certain types of injector devices include safety arrangements that inhibit firing of the injector device until front and rear housing assemblies are disposed in predetermined rotational and axial positions relative to each other.

Abstract: The invention relates to a device (1) for delivering two predetermined doses of a product (3), comprising: —a container (2) for containing said product, said container having a distal end (2d) through which the product is delivered under the distal pressure of a piston, —a pusher (7) movable with respect to said container for causing said piston (4) to move in the distal direction from an initial position, in which none of said product has been expelled to a first position, in which a first dose of said product has been expelled, and to a second position, in which a second dose of said product has been expelled, —a holder body (15) receiving said container and said pusher (7), —biasing means (22) for urging said pusher (7) in the distal direction, from the initial to the first position, and to the second position, —first and second retaining means (9, 11, 19) for maintaining said pusher (7) in said initial position, and in said first position, —first and second actuation means (18) to deactivate said first an

Abstract: A needle-less injector device for delivering a dose of fluid intradermally, subcutaneously or intramuscularly to an animal or human. The device includes an inner housing having opposed ends. A syringe is disposed in one end of the inner housing. The syringe includes a nozzle for delivering a dose of fluid held within the syringe. A plunger is movably disposed within the syringe. A spring powered hammer is movably disposed within the inner housing. The hammer cooperates with the plunger to drive the dose of medicament from the nozzle. An injection delivery spring for powering the hammer is positioned and compressed between the other end of the inner housing and the spring powered hammer. An outer housing slideably supports the inner housing. A skin tensioning spring is mounted between the inner housing and the outer housing, the skin tensioning spring biasing the nozzle of the syringe against the animal or human.

Abstract: The present invention relates to an injection device comprises a generally elongated tubular housing having opposite proximal and distal ends; a needle shield sleeve slidably and coaxially arranged inside the housing and protruding a distance outside the proximal end of the housing; a syringe carrier mechanism comprising a syringe carrier slidably and coaxially arranged to the needle shield sleeve, wherein said syringe carrier comprises a syringe having a medicament and a needle; a first activator member slidably and coaxially arranged to the housing and connected to said needle shield sleeve; an actuating member slidably and coaxially arranged to the first activator member; a drive mechanism slidably and coaxially arranged to the actuating member and to the syringe carrier mechanism, said drive mechanism being controlled by the actuating member; a second activator member slidably and coaxially arranged to the distal end of the housing and fixedly connected to the actuating member; wherein the first and the s

Abstract: The invention refers to a motor mechanism (6) for a drug delivery device (1), comprising a storage drum (8) and a torque drum (9) arranged close to each other and a strip (7) of spring sheet metal having two ends, each end attached to one of the drums (8, 9), wherein the strip (7) of spring sheet metal is coiled on the storage drum (8) in a relaxed state, wherein the motor mechanism (6) is chargeable by rotating the torque drum (9) thereby coiling the strip (7) of spring sheet metal onto the torque drum (9) and bending the strip (7) of spring sheet metal the other way round than in the relaxed state thus arriving in a charged state with the strip (7) of spring sheet metal tending to re-coil onto the storage drum (8) thereby generating a torque.

Abstract: A system and method for a patch-like, self-contained substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir, wherein the device can be attached to a skin surface via an adhesive contact surface and a push button activation assembly can then be used to remove an interlock, allowing a disk, or Belleville spring assembly to apply an essentially even and constant pressure to the contents of the fluid reservoir, allow the release of the patient needles into the skin surface, and establish a fluid communication path between the patient needles and the pressurized fluid reservoir contents. The push button activation assembly further allows the release of one or more improved safety mechanisms after use.

Abstract: The present invention relates to a device for automatic injection of a product, comprising: a body (3) housing a container, the container being movable relative to said body between an initial position, to an insertion position; a safety shield (26) movable with respect to said container and said body between an insertion position to a protection position, when the user removes the device from an injection site; an external socket (48) receiving the body and provided with selection means (53) which can be placed by a user: either in a first position, in which the body (3) and the external socket (48) are bound to each other, the safety shield extending beyond the distal end of both said body and said external socket in the protection position; or in a second position, in which the external socket (48) is able to move axially in the distal direction with respect to the body (3), both the safety shield and the external socket extending beyond the distal end of said body, in the protection position.

Abstract: The invention relates to an automatic injection device (1) for a product contained in a container (50), comprising: a housing (8, 19) receiving the container (50), the container being movable between an initial position and an insertion position, triggering means (23) for initiating the movement of said container (50) from its initial position to its insertion position, said triggering means (23) being in one of a passive state, in which application of a force on said triggering means does not initiate movement of said container (50), and an active state, in which application of said force on said triggering means does initiate said movement, and a safety shield (10) movable with respect to said housing (8, 19) between a first position and a second position, movement of said safety shield (10) from its first position to its second position placing said triggering means (23) in its active state, characterized in that said device comprises: an indicator (19c, 13) that provides an indication to a user of the

Abstract: A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

Abstract: A dispensing device for dispensing medicaments to a patient that is made up of first and second stand-alone, interconnectable assemblies. The first of these assemblies comprises a fluid reservoir assembly that houses a fluid reservoir defining component while the second assembly comprises a fluid delivery and control assembly that includes a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the first assembly toward the patient via a plurality of fluid flow control passageways. Because the stand-alone fluid delivery and control assembly is initially totally separate from the fluid reservoir assembly of the apparatus, the fluid flow passageways of the fluid delivery and control assembly can be effectively sterilized using conventional gamma ray sterilization techniques without adversely affecting the medicament contained within the fluid reservoir of the apparatus.

Abstract: Described is an infusion pump comprising electronic infusion regulating means with wired or wireless communication means and a power source, a medicament bag (7) and an infusion device, said infusion device being in fluid communication with said medicament bag (7) and comprising two valves (1, 2), a pressure cavity (4) provided between said two valves (1, 2) and a membrane (3) covering said cavity (4), wherein said infusion device comprises at least two active actuators, preferably either made of electroactive polymer so as to form a self actuating membrane (3) or made of shape memory alloy wire, one of said actuators being adapted to apply pressure to said membrane (3) for fluid displacement in said cavity (4), and the other of said actuators being adapted to operate one of said valves which is adapted to passively close in the flow direction of a fluid from said medicament bag (7) through the cavity (4), wherein the other of said valves is adapted to, in particular passively, close in a direction opposite t

Abstract: A device for dosed dispensing of a fluid medium is provided with a pen-like housing which has a storage chamber for accommodating the fluid medium and which has at its front end a tip in which there is provided an outlet opening for the fluid medium. Arranged in the front end is a valve element which closes the outlet opening under the force of a spring and is arranged such that it at least partially opens the outlet opening in the event of radial pressure being applied from the outside on the front end of the housing. The valve element is arranged in a tiltable manner at the outlet opening.

Abstract: A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed.

Abstract: A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

Abstract: A device for the dosed administration of a fluid product including a housing, a conveying device for the product, a drive element influenced by the selection of a product dose, a coupling input member coupled to the drive element, a coupling output member coupled to the conveying device, a retaining device which maintains the coupling elements in a maintaining position uncoupled from each other, wherein at least one of the coupling elements is displaceable by a coupling movement from the maintaining position into a coupling state, and wherein a driving force of the drive element causes a delivery movement of the conveying device via the coupling elements.

Abstract: The present application relates to a disposable auto injector (10) that can be safely operated for automatic injection of a dose of medication and having a housing (12) for accommodation of a syringe (18) with a needle (20), the syringe being movably positioned in the housing between a first position in which position the needle is accommodated inside the housing and a second position in which position the needle protrudes outside the housing (22), a driver configured for applying a force to the syringe thereby moving the syringe from the first position to the second position, and wherein the driver is also configured for applying a force to the syringe thereby moving the syringe from the second position to a retracted position in which position the needle is accommodated inside the housing upon user operation of a release member (42).

Abstract: The invention concerns a medical device provided with an outer part or shell and an inner functional part which inner functional part comprises a combination of units. The functional combination of units normally constitutes a device comprising a part being able to penetrate the skin of a patient i.e. a subcutaneous part such as a cannula, a sensor, an insertion needle or the like. Examples of such medical devices are inserter devices and infusion devices where each device comprises an outer part and an inner functional part according to claim 1.

Abstract: A liquid delivery apparatus for the intrathecal delivery of one or more medications to a patient is disclosed. The liquid delivery apparatus generally includes a liquid reservoir, a liquid metering unit fluidly connected to the liquid reservoir, and a catheter delivery tube fluidly connected to the liquid metering unit. Preferably, the liquid delivery apparatus includes two or more liquid reservoirs. In various embodiments, the liquid reservoir includes a deformable balloon and a compressive sleeve spring as a pressure source, the liquid metering unit is a piezoelectrically actuated microvalve, and/or diagnostic sensors are included in the apparatus. The disclosed apparatus are compact, volume-efficient, energy-efficient, capable of delivering accurate fluid volumes, and address problems associated with multi-medication therapies. Methods of operating the liquid delivery apparatus are also disclosed.

Abstract: A two-dose autoinjector for a medicament wherein the locking and releasing of the drive spring of the autoinjector is controlled through stepped guides with ramps for two successive slidings of slides operated by the spring and connected with the syringe and plunger. The guides and the slides are pivotable relative to one another and the sliding direction, while the syringe can only slide axially To enable or disable the sliding of the slides within the guides an angularly angularly mobile arming member is provided formed with a guide track substantially equal to that of the stationary member where the guides are formed.

Abstract: A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug deliver pump.

Abstract: The present invention relates to a device for expelling a predetermined quantity of medicament comprising driving means comprising an energy-accumulating member, a nut, and a driver for driving a pressure means; and activation means for activating said driving means wherein said pressure means comprises a movable wall part arranged inside a 2 container and a threaded plunger rod arranged to interact with said driving means for pushing said movable wall part forwardly, and wherein said activation means comprises a manually operated push button arranged on the front end of the device for promoting an ergonomic handling of the device and wherein said activation means are capable of interacting with said driving means in a stepwise mode; such that each time said push button is depressed said pressure means moves an step exerting pressure on the medicament inside the container and expelling a predetermined quantity of the medicament through the opening.

Abstract: An automatic injection device including a housing element, at least one resilient element arranged to be located within the housing element, a syringe including at least one syringe piston, a needle guard adapted for selectable positioning with respect to the housing element and a selectable driving element adapted, when actuated, to be driven by the at least one resilient element for initially displacing the syringe relative to the housing element from a non-penetration position to a penetration position and thereafter displacing the at least one syringe piston in the syringe to effect drug delivery and displacing the needle guard into a needle guarding position.

Abstract: A hazardous agent injection system including from about 0.02 ml to about 4.0 ml of methotrexate at a concentration of from about 7.5 mg/ml to about 150 mg/ml; a needle-assisted jet injector including a container configured to contain the methotrexate; a injection outlet member associated with the container; an injection-assisting needle coupled to the injection outlet member; a firing mechanism associated with the container; an energy source associated with the firing mechanism; and a trigger mechanism associated with the firing mechanism, wherein the needle-assisted jet injector is configured to eject the methotrexate from the injection outlet member such that the Cmax, Tmax and bioavailability of the needle-assisted jet injected methotrexate falls between about 80% and about 125% of the Cmax, Tmax and bioavailability of methotrexate delivered by a hand-powered syringe.

Abstract: The invention relates to an injection device (1) being in one of a passive and active state, triggering of injection being prevented when said device (1) is in its passive state and permitted when said device (1) is in its active state, having: a housing (30, 30a, 30b) receiving a container, the container being in one of a passive state and an active state, movement of the container out of its initial position being prevented when the container is in its passive state, and being permitted when the container is in its active state, and a safety shield (40) coupled with the housing (30) and being movable with respect to the housing along a movement path having a predetermined length, first retaining means (60, 61, 54a) for maintaining the container (20) in its passive state, second retaining means (34a, 81b) for maintaining said device (1) in its passive state, said device (1) being characterized in that it comprises: first deactivating means (50, 53) and second deactivating means (50, 50a) movable coinciden

Abstract: Remote controls, including a communication device, a button or other communication device actuator and a movable structure that allows actuation of the actuator in one position and prevents actuation of the actuator in another position to prevent inadvertent signal transmission.

Abstract: An injection device including a receiving device movable in an insertion movement relative to the injection device, a tensioning element, e.g. a spring, which bears on a part of the injection device, and a coupling element for coupling the receiving device to the spring such that, during an insertion movement of the receiving device the spring is tensioned. In some embodiments, the invention encompasses a method for preparing an injection device for dispensing a substance from an ampoule, wherein a discharging spring of the injection device is tensioned by introduction of the ampoule into the injection device.

Abstract: A method and device for relieving muscle tension and spasms in a user's head, neck, shoulders and back is provided. The method and device may be used by an individual to apply pressure to specific pressure points on the trapezius muscles of the user's shoulders, sub-occipital area of the user's neck and rhomboid and thoracic paraspinal region of the user's back.

Abstract: An administering device for a fluid product includes a product receptacle that accommodates the product to be administered, a fluid reservoir for a driving fluid, a driving means, a product chamber, and a fluid connection. The product receptacle includes an opening at a forward end and a product stopper at a rear end. The driving means acts upon the fluid reservoir, the pressure chamber adjoins the product stopper while the fluid connection is located between the fluid reservoir and the pressure chamber, and the driving means acts upon the fluid reservoir in such a way that the pressure chamber is impinged upon by pressure which affects the product stopper and the product is discharged from the product receptacle.

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible drug container that can be filled in the field with the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

Abstract: An injection device 110 is described having a housing 112 that receives a syringe 114. The syringe 114 is biased by a return spring 126 from an extended position in which the needle 118 extends from the housing 112 through an exit aperture 128 to a retracted position in which it does not. A drive spring 130 acts via a drive to advance the syringe 114 from its retracted position to its extended position and discharge its contents through the needle 118 and a return spring 126, brought into play when the drive has reached a nominal return position, restores the syringe 114 to its retracted position. A releasable locking mechanism retains the syringe 114 in its retracted position. A sleeve 119 projects from the exit aperture 128 and can be depressed to release the locking mechanism.

Abstract: A system to minimize fluid turbulence inside a tissue cavity during endoscopic procedures. A body tissue cavity of a subject is distended by continuous flow irrigation using a solenoid operated pump on the inflow side and a positive displacement pump, such as a peristaltic pump, on the outflow side, such that the amplitude of the pressure pulsations created by the outflow positive displacement pump inside the said tissue cavity is substantially dampened to almost negligible levels. The present invention also provides a method for accurately determining the rate of fluid loss into the subject's body system during any endoscopic procedure without utilizing any deficit weight or fluid volume calculation, the same being accomplished by using two fluid flow rate sensors. The present invention also provides a system of creating and maintaining any desired pressure in a body tissue cavity for any desired cavity outflow rate.

Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible, pre-filled drug container that contains the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.