Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. Embodiments include removing a substantially cylindrical cap from an inserter to expose a substantially cylindrical sleeve, removing a cover from a substantially cylindrical container holding sensor components, and fitting the sensor components into the inserter.

Abstract: A safety syringe (100; 700; 1200) comprising: a barrel (104; 704; 1204) having an opening at an end thereof; a syringe plunger (108; 708; 1208) configured to move within the barrel such that an inward stroke of the syringe plunger causes a substance within the barrel to be expelled from the opening; and a sheath (112; 712; 1212) configured to cover at least partially the opening in the barrel after use of the syringe, wherein the sheath is coupled to the syringe plunger and is configured to decouple from the syringe plunger at a point on the inward stroke such that the sheath is moveable independently of the syringe plunger and further movement of the sheath after decoupling at least partially covers the opening in the barrel.

Abstract: Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The housing cavity is arranged for receipt of a syringe suitable for delivery of a drug to a patient. The syringe has a barrel for containing a volume of a liquid drug formulation, the barrel defining a flange at the rear end thereof and a forward shoulder at the forward end thereof. The cassette unit includes one or more shoulder support features for supporting the forward shoulder of the syringe. In use, the one or more shoulder support features act to direct a major part of an applied load path to travel through the shoulder at the forward end of the syringe and lesser load to pass through the flange at the rear end thereof.

Abstract: An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement. Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating.

Abstract: A substance delivery device (autoinjector) for use with a container (such as a syringe) containing the substance includes: a body arranged to house or hold the container; a plunger which is movable with respect to at least a portion of the body, the plunger being arranged to act upon the container so as to move the container with respect to the portion of the body; wherein the plunger is also arranged to expel at least a portion of the substance from the container; and wherein the device includes elements for adjusting the amount of substance to be expelled from the container. The device can also have elements for priming the container, and can accommodate containers of different size or shape.

Abstract: Described is a medicament cartridge comprising a housing having open proximal and distal ends, a first coupling mechanism, and a syringe slidably disposed in the housing. The syringe includes a needle and has a retracted position in which the needle is covered by the housing and an extended position in which the needle is exposed. A delivery device comprises the medicament cartridge, an actuator comprising a plunger, a motor adapted to translate the plunger, a second coupling mechanism adapted to detachably engage the first coupling mechanism, and a control button adapted to actuate the motor. A carrier comprises a first slot for at least partially containing the actuator, a second slot for at least partially containing the medicament cartridge, a user interface adapted to provide at least one a visual signal and an audible signal.

Abstract: An apparatus includes a housing, a medicament container, an actuator, and a biasing member. The actuator is configured to move the medicament container within the housing when the actuator is moved from a first configuration to a second configuration. The actuator includes a gas container and a puncturer. When the actuator is in the first configuration, a portion of the puncturer is disposed apart from the gas container. When the actuator is in the second configuration, the portion of the puncturer is disposed within the gas container. The gas container has a longitudinal axis offset from a longitudinal axis of the medicament container. The biasing member is configured to bias the actuator toward the second configuration.

Abstract: An injector device includes an injector body that receives a syringe; and an injection assembly being configured to dispense medicament from the syringe in a dispensation step. Certain types of injector devices include a sudden completion indicator that indicates when the injection is completed. Certain types of injector devices are configured to dispense two different medicament formulations having different viscosities from syringes without making any changes to the injector devices other than to switch out the syringes. Certain types of injector devices include safety arrangements that inhibit firing of the injector device until front and rear housing assemblies are disposed in predetermined rotational and axial positions relative to each other.

Abstract: An injection device with distal and proximal ends includes a housing, a needle-protecting sleeve that is longitudinally movable relative to the housing, a container holder that is longitudinally movable relative to the housing toward the proximal end from a non-delivery position to a delivery position, and a needle-protecting sleeve spring that is operatively coupled between the needle-protecting sleeve and the container holder such that the sleeve is longitudinally movable toward the distal end from an initial position to an activating position and toward the proximal end from the activating position to an end position. The sleeve spring is strained by a first amount when the sleeve moves from its initial position to its activating position, and by a second amount when the container holder moves from its non-delivery position to its delivery position.

Abstract: An assembly for a drug delivery device is provided comprising a housing, a cartridge holder releasably connectable to the housing, a resilient member, and an interaction member which is configured to mechanically cooperate with the resilient member and with the cartridge holder. The resilient member is configured to rotationally bias the interaction member. The assembly has a locked state where the cartridge holder is connected to the housing, the cartridge holder being obstructed from movement with respect to the housing, and an unlocked state where the connection between the cartridge holder and the housing is released, the cartridge holder being freely moveable with respect to the housing.

Abstract: According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud slibably arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).

Abstract: An auto-injector comprising a housing containing a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament. A spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and retracting the syringe with the needle into the covered position after delivering the medicament. A trigger locks the spring in a pressurized state prior to operation and, upon manual operation, releasing the spring for injection. An interlock sleeve telescoped in the housing and translatable in longitudinal direction, wherein in a proximal position the interlock sleeve is arranged to be coupled to the syringe in the syringe's retracted position and wherein the interlock sleeve in its distal position is arranged to allow decoupling of the syringe.

Abstract: An injection device includes a housing having a receptacle for a vessel for holding injection fluid; an operator-manipulated element for setting an injection dose; a dosing member rotatable about a longitudinal center axis relative to the housing when setting the injection dose; a feed part; and, a latching unit acting between the feed part and housing. The dosing member has a zero position whereat no dose is set and an injection position whereat an intended dose of injection fluid is set. A spring acts between the dosing member and the housing to return the dosing member from an intermediate position to the injection position or a zero position.

Abstract: An injection device includes a housing for receiving a syringe or cartridge for containing a medicament; a rotary driveshaft mounted for rotation relative to the housing; and an elongate coiled torsion spring having respective formations at opposite ends thereof, with a first formation being anchored in a seat on the rotary drive shaft and a second formation being anchored in a seat on a reaction component. In use relative rotation of the rotary driveshaft and the reaction component in one angular direction strains the torsion drive spring, and release of the strained torsion drive spring causes expression of medicament from the syringe or cartridge. The torsion spring is longitudinally resiliently compressible between its end formations whereby during assembly of the injection device, the torsion spring may be longitudinally compressed and then rotated, thereby urging the end formations of the torsion drive spring into engagement with the respective seats.

Abstract: An engine for an-auto injector for administering a dose of a liquid medicament includes a case arranged to be attached to a package syringe containing a syringe. The case contains a drive capable of, upon activation, pushing the needle from a covered position into an exposed position, and operating the syringe to supply the dose of medicament. The case contains a trigger arranged to lock the drive in a loaded state prior to manual operation and capable of, upon manual operation, releasing the drive for injections. The drive is arranged as a gas spring including a cylinder and a piston with a plunger for transmitting the spring force. A latch is arranged for preventing translating between the cylinder and the case. The latch is disengageable by the released gas spring being at least nearly fully extended thus allowing the extended gas spring to be translated in a distal direction.

Abstract: A medicament delivery device is presented having a housing configured to receive a medicament container having a delivery member and a shield, a protective cap, and wherein the protective cap comprises connecting means for connecting to the shield of the medicament container such that removal of the protective cap from the housing causes removal of the shield from the medicament container. The delivery device is characterized in that a protective cap assembly has a first disconnecting means configured to interact with corresponding second disconnecting means of the housing and of the protective cap such that activation of the first disconnecting means of the protective cap assembly causes the displacement of the protective cap relative to the housing.

Abstract: A cartridge insertion assembly including apparatus with a pathway formed therein, a cartridge including a cartridge coupling element connectable to an activation mechanism disposed in the apparatus operative to cause a substance contained in the cartridge to be metered out of the cartridge, and a door pivoted to the apparatus that includes a door coupling element arranged with respect to the cartridge such that when the door is in a fully closed position, the door coupling element couples the cartridge coupling element with a coupling element of the activation mechanism.

Abstract: A medicament delivery device comprises a housing, a telescopic piston rod assembly for driving a bung of a medicament container, and a drive mechanism for the telescopic piston rod assembly. The telescopic piston rod assembly comprises a plunger for driving a bung, a key for allowing predominantly axial movement between the plunger and the housing and an input drive telescopically coupled to the plunger and supported for rotational and axial movement relative the housing. The drive mechanism additionally comprises a transfer drive that operates to rotate the input drive. As the input drive rotates, it moves axially relative to the housing, expanding telescopically relative to the plunger.

Abstract: The invention relates to an insertion device comprising—a penetrating member (50) connected to transformation means (52), —a moving part (38) comprising guiding means (39) which guiding means (39) restrict the movement of the transformation means (52) and guide the penetrating member (50) from a first to a second position in a first direction, i.e. the direction of insertion, towards the injection site, and—a stationary housing (30) comprising guiding means (32) which guiding means (32) restrict the movement of the moving part (38). The guiding means (32) guide the moving part (38) in a second direction which is linear and different from the first direction i.e. the direction of insertion.

Abstract: Described is an autoinjector comprising a case, a needle shroud slidably arranged in the case, a chassis slidably arranged in the case and rotatably coupled to the needle shroud, an outer plunger selectively engaged to the chassis, an inner plunger selectively engaged to the outer plunger, and a drive spring applying a biasing force to the outer plunger. The biasing force is applied to the inner plunger when the inner plunger is engaged to the outer plunger. Axial movement of the needle shroud relative to the case causes rotation of the chassis relative to the needle shroud. The rotation of the chassis causes the inner plunger to rotate relative to the outer plunger and disengage the outer plunger to remove the biasing force from the drive spring on the inner plunger.

Abstract: An IV set is configured for coupling with a pump device. The IV set comprises a fluid lumen adapted for passage of an infusion fluid toward a patient. A frame is coupled to the fluid lumen and is adapted to be inserted into a seat of a pump device, wherein the frame provides a platen relative to the fluid lumen, wherein the frame is sized and shaped such that the frame can only be inserted into the pump device when aligned in a predetermined orientation relative to the pump device. An information device is adapted to store information associated with the IV set, wherein the information device is accessed in response to proper placement of the IV set in the pump device.

Abstract: An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement. Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing, a syringe with needle and a stopper, a drive spring for pushing the needle from a covered position into an advanced position, for operating the syringe and for retracting the syringe, activating means for locking or releasing the spring means. A retraction sleeve is axially movable arranged in the housing. The drive spring bears with its proximal end against a thrust face of a decoupling member. At least one resilient decoupling arm is arranged at the decoupling member for bearing against a first shoulder of the plunger. At least one aperture is arranged in the retraction sleeve allowing the decoupling arms to be flexed outward thus allowing the first shoulder to slip past the decoupling arm.

Abstract: The invention refers to an auto-injector comprising: a body, a syringe with a hollow injection needle and a stopper, wherein the syringe is slidably arranged with respect to the body, a torsion spring capable of, upon activation: pushing the needle from a covered position inside the body into an advanced position through the orifice and past the proximal end (P), operating the syringe to supply the dose of medicament (M), and activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection, wherein the torsion spring is grounded at one end in the body and at the other end in a first gear member rotatable about a longitudinal axis, wherein the first gear member, upon rotation, is arranged for translating a second gear member toward the proximal end (P), the second gear member prevented from rotating and arranged to be coupled to the stopper in order to push it towards the proximal end (P), wher

Abstract: An injection device includes a housing (40) for containing a syringe or cartridge (14) of medicament; a rotary drive shaft (20) for being rotated by an adjustable preset amount to cause expression of a corresponding amount of medicament from the syringe or cartridge; a torsion drive spring (24) anchored at one end region relative to the drive shaft (20) and, at its other end region being secured to a fitting (44) adapted to non-rotatably engage a seat (48, 50) on the housing.

Abstract: An auto-injector comprising a housing arranged to contain a syringe. The syringe is slidably arranged with respect to the housing, a spring capable of pushing a needle from a covered position into an advanced position, operating the syringe to supply a dose of medicament, and retracting the syringe into a covered position and an activator. The spring is arranged to be grounded in the housing for advancing the needle and for injecting the dose of medicament. The drive spring grounded in the housing switched to its proximal end for retracting the syringe. An interlock sleeve telescoped within the housing. The activator comprises a trigger, wherein the trigger button is locked, thereby preventing actuation when the interlock sleeve is in its proximal position in an as delivered state and wherein translation of the interlock sleeve unlocks the trigger button so as to allow actuation.

Abstract: A substance delivery device (autoinjector) for use with a container (such as a syringe) containing the substance includes: a body arranged to house or hold the container; a plunger which is movable with respect to at least a portion of the body, the plunger being arranged to act upon the container so as to move the container with respect to the portion of the body; wherein the plunger is also arranged to expel at least a portion of the substance from the container; and wherein the device includes elements for adjusting the amount of substance to be expelled from the container. The device can also have elements for priming the container, and can accommodate containers of different size or shape.

Abstract: A needle does not come off even if a high back pressure occurs at the skin upper section. Thus, the drug leakage from the skin can be prevented. A drug administration device 1 includes a tubular section 2 having a fluid chamber 7 capable of accommodating a drug and a discharge section 22, a pusher member 3 moving within the tubular section 2, a grip section 4, and a connection section 5. The pusher member 3 includes a rod-shape plunger 31 and a gasket 32. The grip section 4 is disposed along the outer periphery of the tubular section 2 and kept away from the tubular section 2, and the connection section 5 is formed between the tubular section 2 and the grip section 4.

Abstract: A medication injection pen (11) includes a housing (1) and a dose set knob (2) rotatable with respect to the housing (1). A brake assembly (68) is disposed in the housing (1) and has a ratchet member (43). A driver (21) includes at least one external tooth (57) engaging the ratchet member (43). The engagement between the ratchet member (43) and the at least one external tooth (57) substantially prevents the driver (21) from rotating with respect to the dose set knob (2) during dose setting and dose correcting. The engagement between the ratchet member (43) and the at least one external tooth (57) allows the driver (21) to rotate with the dose set knob (2) during an injection.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising a housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing, drive means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, and operating the syringe to supply the dose of medicament, and activating means arranged to lock the drive means in a loaded state prior to manual operation and capable of, upon manual operation, releasing the drive means for injection, characterized in that the drive means is at least one spring essentially transversally arranged with respect to a longitudinal axis of the syringe at least when in the loaded state.

Abstract: An auto-injector comprising an elongate housing arranged to contain a syringe and displacing medicament, wherein the syringe is slidably arranged with respect to the housing, spring capable of: pushing a needle from a covered position inside the housing into an advanced position, operating the syringe to supply a dose of medicament, and retracting the syringe with the needle into the covered position. Activating means is arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection. The spring is a single drive spring arranged for advancing the needle and for injecting the dose of medicament via a plunger. A damper is arranged with the plunger by a spline so as to cause rotation of either the plunger or the damper at least during part of a translation of the plunger in proximal direction.

Abstract: In an injection device a rotary indicator element (20) indexes angularly between a pre-firing position to an injection complete position to create a visual and audible/tactile signal as the drive plunger (28) arrives at or near its fired position. The indicator element (20) has a saw tooth profile which co-operates with respective abutments (34, 40) on the plunger and a housing part of the device to control and energise indicator movement.

Abstract: A medicament delivery device has a housing for a medicament container and a drive unit for a stopper in the container to expel a dose of medicament, the drive unit having a plunger rod and a dual back-to-back force spring assembly connected to the plunger rod; and a lock and release mechanism connected to the drive unit that has a hold member connected to the plunger rod, a rotator member connected to the hold member, and a tubular actuation member linearly slidable in relation to the housing and connected to the rotator member. The hold member is attached to the housing and has a generally tubular lock tube through which the plunger rod extends and two half-cylindrical seats for the dual back-to-back force spring assembly. The lock tube has a resilient lock and release device to interact with both the plunger rod and the rotator member.

Abstract: A device for the automatic injection of doses of a drug compound is described. The device has a sliding sheath which, when depressed with its front end against the injection site, interacts with cam means to activate triggering of a plunger, thus controlling delivery of a drug dose. Plunger guide means are provided for controlling the triggering sequence and means for arming the device in the dose delivery condition. Automatic needle re-sheathing and resetting of a lock-out condition after each dose is delivered are also provided.

Abstract: An autoinjection device includes a main body in the front end of which is slideably mounted a drawer or front body portion. The drawer can be opened to remove or insert a syringe. Closing the drawer whilst pressing a multifunction button primes the drive mechanism by latching it against trigger latch. Pressing the button gain whilst urging the front end causes the drawer to release the trigger latch. After the injection the drawer shrouds the used needle and can be released only by pressing the button.

Abstract: An injector including a syringe arranged along a longitudinal axis, a removable cover for removable engagement with the syringe and a cover removal assembly including an outer portion which is engagable by a user and is movable axially in a cover disengagement direction along an axial travel path with respect to the longitudinal axis and an inner portion which includes at least one engagement portion which is engagable with the removable cover, whereby axial movement of the inner portion in the cover disengagement direction removes the removable cover from the syringe, at least one of the outer portion and the inner portion being configured such as to provide an axially floating lost motion engagement between the outer portion and the inner portion.

Abstract: An injection device (110) comprises a housing (112) adapted to receive a syringe (122) having a discharge nozzle (118), an actuator (114) and a drive (120) acted upon the syringe to advance it from a retracted position in which the discharge nozzle is contained within the housing to an extended position in which the discharge nozzle is contained within the housing to an extended position in which the discharge nozzle extends from the housing. There is a locking mechanism (HS) in communication with the actuator and activatable to be moved from a locked position in which the actuator is prevented from releasing the drive to an unlocked position in which the actuator is operable to act upon drive to advance the syringe. The locking mechanism or the housing includes integrally formed biasing means (210) adapted to return the locking mechanism to a locked position when it is not activated. There is no need for separate springs to be used bias to the releasable locking mechanism out the housing.

Abstract: A pump apparatus that exerts a constant force on a bag of fluid to provide a uniform flow rate compared to elastomeric pumps. The apparatus comprises a first and a second block member positioned over a plate, which are moveable to define an opening to receive a wedge member attached on the plate. The block members are coupled by a resilient means that is extendable when the wedge member is urged into the opening. The extended resilient means is retractable such that the plate exerts a constant force on the bag to expel fluid in a uniform flow rate.

Abstract: An injection device having a distal end, and including a needle located inside the injection device in an initial position, wherein the needle is moveable to a puncturing position in which the needle projects from the distal end, an open region located distally relative to the needle in the initial position of the needle and having a dimension, and a reduction piece moveable relative to the opening region whereby the dimension may be reduced.

Abstract: A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug delivery pump.

Abstract: An apparatus includes a label configured to be coupled to a medicament delivery device. The label includes a first surface and a second surface. The first surface is configured to be coupled to an outer surface of the medicament delivery device. The second surface includes a textual indicia. The label further includes an electronic circuit system configured to output an electronic signal.

Abstract: Various exemplary embodiments relate to a medicament storage case including: a case body securable to a wall; a door connected to the body; a sleeve to contain an epinephrine injector; a medicament lock including a hook, wherein the hook is positioned to engage the sleeve when in a first position and is positioned to disengage the sleeve when in a second position; an actuator including a solenoid, wherein the solenoid, upon activation, moves the hook from the first position to the second position; a microphone configured to receive first audio as input; a speaker configured to output second audio; a communication unit configured to provide Internet connectivity; a button; and a processor configured to: in response to pressing the button: establish communication between the local user and a remote site, receive an unlock message, and in response to receiving the unlock message, activate the solenoid to release of the sleeve.

Abstract: The present invention provides an improved injection assisting device wherein the improvement comprises an injection lock indicator located between the first and the second outer shell and the outside of the indicator window, configured to indicate to a user whether the injection locking member is in a locked state, and configured to substantially contrast in color with both the first outer shell and the second outer shell, which first and second outer shells contrast in color with each other, and configured to be substantially shielded from a view of a user in the presence of the predetermined amount of compression force on the second outer shell.

Abstract: A needle assembly adapted for fluid communication with a cartridge containing a substance to be delivered to a subject, the needle assembly characterized by a biasing device (70) arranged to apply a biasing force on a needle (28, 116) to cause the needle (28, 116) to protrude outwards of a housing (30, 112) to pierce the subject, and biasing device release apparatus (60) including a biasing device arrestor (62) that initially blocks movement of the biasing device (70) and which releases the biasing device (70) when the safety latch (32, 122) moves to a position that permits moving the needle holder (26, 118) to cause the needle (28, 116) to protrude outwards of the housing (30, 112).

Abstract: A device for the automatic injection of doses of a drug is described. The device has a slide and cam means, a syringe unit with a piston, and guide means. The axial movement of the slide initiated by a user by depressing its front end against an injection site, causes an angular displacement of the cam means that, in cooperation with the guide means, controls movement of the syringe piston and therefore administration of a drug dose.

Abstract: Devices and methods for delivering a fluid to a patient are disclosed herein. In one embodiment, a delivery system includes a reservoir for containing a fluid and a fluid communicator in fluid communication with the reservoir. An electrochemical actuator is coupled to the reservoir and configured to exert a force on the reservoir upon actuation such that fluid within the reservoir is communicated through the fluid communicator. The actuator includes a first end that is constrained and a second end that is not constrained. The actuator is configured to bend at a location along a length of the actuator when actuated such that the second end of the actuator is displaced in a direction toward the fluid reservoir. The actuator can be an electrochemical actuator. The apparatus can further include a transfer structure disposed between the actuator and the reservoir configured to contact the reservoir upon actuation of the actuator.

Abstract: The invention refers to an auto-injector for administering a medicament (M), comprising of a chassis, a syringe with a hollow needle and a stopper; a drive spring capable of, upon activation: advancing the needle (3), injecting the medicament (M), and retracting the syringe with the needle after delivering the medicament (M); and; activating means arranged to lock and release the drive spring, wherein the drive spring is a compression spring arranged to be grounded at a distal end in the chassis for advancing the needle and for injecting the dose of medicament (M) via a plunger and wherein the drive spring is arranged to have its ground in the chassis switched to its proximal end for retracting the syringe.

Abstract: A catheter assembly includes a catheter, including an inner member and a sheath, extending from a handle. The handle includes a housing, a braking assembly, a carriage and a carriage driver. The braking assembly comprises a braking element within the housing interior and a braking element rotator. The carriage comprises at least one carriage braking surface engaging the braking element. The carriage driver, such as a spring, biases the carriage towards the proximal end of the handle. The inner member has a proximal end secured to the housing. The sheath has a proximal end secured to the carriage. Rotating the braking element causes the carriage to move proximally as the carriage braking surface slides along the braking element. This causes the sheath to move proximally relative to the inner member.

Abstract: An actuation mechanism for an automatic injector includes a first actuation spring, a first actuation pill, a second actuation spring, and a second actuation pill. In an initial configuration the first actuation spring resides in a compressed, energized state substantially within an upper portion of first actuation pill and the second actuation spring resides in a compressed, energized state between the first actuation pill and the second actuation pill. An automatic injector includes a housing, an activation mechanism, an actuation mechanism, and a syringe cartridge having a plunger and a needle assembly. A retractable syringe may be utilized as a syringe cartridge, such as a prefilled retractable syringe with integrated safety features which retract the needle after use. The automatic injector may be utilized to inject the needle, deliver a drug treatment, and activate retraction of the needle. Methods of assembly and operation are also provided.

Abstract: A low profile and volumetrically efficient medication delivery device configured to be placed on the body of a patient during fluid delivery to the patient is provided. The device incorporates a low profile actuator assembly that causes fluid delivery by displacing a collapsible reservoir in response to receiving an electrical current or charge input from a programmable controller and a power supply. Additional components help prevent drug theft or abuse, measure actuator pressure, displacement and temperature in real time providing active feedback to the controller that is controlling the actuator. The device also has wireless communication capabilities.