Material Impelled By Spring Patents (Class 604/134)
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Patent number: 5779677Abstract: The injector has a reservoir containing a drug. The injector has a tubular body with a tubular wall, a plunger, a needle and a plunger rod. The tubular body also has two springs. The first spring is compressed from bearing on a part of the inner surface of the tubular body and on a piece that is connected to the plunger rod. The first spring pushes in the direction in which the needle protrudes. The second spring acts in the opposite direction of the first spring. The second spring is compressed by bearing on a part of the inner surface of the injector body and on a ring. The force exerted by the second spring is greater than that exerted by the first spring. The ring is slidably mounted and is capable of entraining the reservoir in the direction of the retraction of the needle. The ring is blocked by a movable abutment. The plunger rod cooperates with the movable abutment to release the second spring and cause the retraction of the needle.Type: GrantFiled: August 1, 1996Date of Patent: July 14, 1998Assignee: Laboratoire AguettantInventor: Pierre Frezza
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Patent number: 5743878Abstract: An infusion pump for infusing a medical treatment fluid intravenously to a patient includes a collapsible treatment fluid bag juxtaposed with an inflatable drive fluid bladder confined between a pair of opposing containment members which cause the bladder to impinge against the bag as the bladder is inflated. A drive fluid pump controllably inflates the bladder, thereby displacing treatment fluid from the bag into an outlet tube affixed thereto which conveys the treatment fluid to the patient where it is received intravenously. The treatment fluid flow rate through the tube is controlled by increasing or decreasing the drive fluid pump output and consequently the pressure in the bladder in response to a pressure sensor in fluid communication with the bladder. Alternatively, the treatment fluid flow rate is adjusted by opening or closing the outlet tube by means of an occluder or restrictor positioned along the tube.Type: GrantFiled: December 11, 1995Date of Patent: April 28, 1998Assignee: Medication Delivery Devices, Inc.Inventors: Stephen O. Ross, Mark D. McWilliams
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Patent number: 5735824Abstract: An injection device is provided for the infinitely variable metering and administering of a liquid preparation from a multi-dose injection cartridge having a rear piston which may be moved forward by means of a piston rod. The longitudinal movement of the piston rod is governed by two couplings arranged along the piston rod and each being capable of releasably gripping the piston rod by a locking device. The piston rod has a wedge-shaped cross section and each of the couplings includes a clamping shoe which has a wedge-shaped groove, the cross section of which is adapted to that of the piston rod, and locking device, by which the piston rod and each clamping shoe may be releasably clamped together to lock the piston rod in the groove of said clamping shoe.Type: GrantFiled: January 30, 1995Date of Patent: April 7, 1998Assignee: Pharmacia & Upjohn AktiebolagInventor: Birger Hjertman
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Patent number: 5722956Abstract: A syringe driver device is able to effect the controlled, parenteral infusion of a medical fluid using an available disposable syringe. The driver device includes a frame heaving a movable carriage, which houses a force applying element, mounted thereto. A disposable syringe mounts upon the frame and a lengthy microbore tubing attaches to the outlet tip of the syringe. As a force is applied to the syringe plunger, fluid is expelled from the syringe, but its flow rate is dependent upon the diameter of the microbore tubing. The driver device enables the delivery of multiple, sequential doses of fluid.Type: GrantFiled: August 14, 1996Date of Patent: March 3, 1998Assignee: The General Hospital CorporationInventors: Nathaniel M. Sims, Michael H. Wollowitz, David M. Wrightson
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Patent number: 5665070Abstract: An infusion pump for providing a pressurized liquid flow from a collapsible, deformable reservoir bag includes a magnetically actuated pressurizing member that applies a pressure to the bag in response to the force of magnetic attraction applied by a magnet. In several embodiments, a bag is seated on a platen of magnetizable metal, and a magnet with a compressing surface is mounted for movement toward and away from the platen. As the magnet is moved toward the platen by the force of magnetic attraction, the bag is pressurized between the magnet and the platen. The magnet may be spring biased either toward or away from the platen to alter the relationship between the decreasing volume of the bag and the pressure applied to it, by compensating in a known manner for the change in the magnitude of the magnetic force with the distance between the magnet and the platen.Type: GrantFiled: January 19, 1995Date of Patent: September 9, 1997Assignee: I-Flow CorporationInventor: Charles J. McPhee
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Patent number: 5665071Abstract: A reloadable automatic or manually usable medicine injection apparatus having a barrel which receives a syringe subassembly. The syringe subassembiy includes an ampule for housing fluid medication, a needle, a plunger stopper, and plunger shaft which allow removal and manual use. The injection apparatus includes a driver for forcing the syringe subassembly to inject the needle and displace fluid medication. The injection apparatus preferably includes a trigger handle, sheath remover, and removable stop system for delivery of multiple doses.Type: GrantFiled: June 26, 1996Date of Patent: September 9, 1997Assignee: Washington Biotech Corp.Inventor: Ronald E. Wyrick
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Patent number: 5643214Abstract: An injection device is adapted to eject a sequence of doses from the needle of a capsule carried within its barrel-like body. A plunger extending rearwardly from the capsule has ratchet teeth along its length engaged by pawls at the forward end of a drive tube biased forwardly by a spring. The capsule is in a sleeve-like carrier having limited longitudinal travel, a lost motion connection to the drive tube and an engagement with the ratchet teeth by pawls. The drive tube can be releasibly retained in a rearward position by a trigger mechanism. When released, the drive tube urges the plunger, capsule and carrier forwards to project the needle. The liquid acts effectively as a solid. With the carrier stopped, the plunger carries on to eject a dose, clicking past the carrier pawls. The re-prime, the knob is pulled to retract the drive tube and the carrier, the lost motion connection allowing the drive tube to move further and have its pawls click back along the plunger until the trigger mechanism re-engages.Type: GrantFiled: January 18, 1995Date of Patent: July 1, 1997Assignee: Owen Mumford LimitedInventors: Jeremy Marshall, Derek Turner
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Patent number: 5607418Abstract: An implantable drug delivery apparatus including a housing that has a housing chamber. An outer deformable body having a reserve chamber is mounted within the housing chamber. An inner deformable body having a dispensing chamber is mounted within the reserve chamber. A dispensing valve is actuated to an open position to allow a fluidic drug to flow from the dispensing chamber, through the dispensing valve and through a catheter into a body of a patient. The fluidic drug is discharged from the dispensing chamber at a dispensing mass flowrate which is greater than a refilling mass flowrate of the fluidic drug passing from the reserve chamber to the dispensing chamber, when the dispensing valve is in an open position.Type: GrantFiled: August 22, 1995Date of Patent: March 4, 1997Assignee: Illinois Institute of TechnologyInventor: Robert C. Arzbaecher
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Patent number: 5599309Abstract: An injection device holds a syringe in the form of a capsule having a needle projecting from its forward end and a plunger extending from its rear end. The rear end of the plunger received in the drive member, which, when released, is urged forward by a coil spring, thus projecting the needle and expressing the dose. The drive member is held captive in its rearward primed position by a detent provided by the body of the device. A sleeve covering a substantial part of the body can shift longitudinally of it from an initial rearward position to a forward position in which it either disengages the drive member from the detent, or in which a trigger is freed from actuation to release the drive member.Type: GrantFiled: September 25, 1995Date of Patent: February 4, 1997Assignee: Owen Mumford LimitedInventors: Jeremy Marshall, David D. Crossman
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Patent number: 5549562Abstract: An apparatus for the infusion of a liquid contained in an infusion bag. The apparatus includes a plate for receiving an infusion bag, and a box having a closable lid. Interaction between the lid, the plate and an elastic spring mechanism located inside the box results in the expulsion of fluid from the infusion bag. The elastic spring mechanism includes four arms that articulate in pairs to form two cross structures that are biased together with springs. Respective ends of the two cross structures are connected by rollers, while opposing ends of the two cross structures are connected to inside portions of the box.Type: GrantFiled: September 29, 1994Date of Patent: August 27, 1996Assignee: A.D.E.C.E.F.Inventors: Jean-Jacques Piclin, Gilbert Thibaut, Michel Boisson
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Patent number: 5480387Abstract: An injection device (10) is adapted to receive a cartridge (11) holding injection fluid (12). This cartridge (11) is displaceable in the proximal direction in the injection device counter to the force of a resetting spring (157). An adjustable-length tappet (80) is biased in the proximal direction by a spring (53), is displaceable in the injection device between a proximal end position and a distal end position, and has a threaded spindle (19) which is guided in the thread (17) of an adjusting member (15), serves to act upon a plunger (23) provided in the cartridge (11), and has a guide member (67) associated with it; the guide member is connected to it in a manner fixed against relative rotation but axially freely displaceably. This guide member (67) is rotatable relative to the housing (100) of the injection device (10) in the distal end position of the tappet (80), but not in the proximal end position thereof.Type: GrantFiled: August 24, 1994Date of Patent: January 2, 1996Assignee: Medico Development Investment CompanyInventors: Jochen Gabriel, Herbert Bechtold
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Patent number: 5478316Abstract: A device for automatically injecting a material into the body is disclosed. The device includes a drive assembly and a syringe assembly which is mounted to the drive assembly. The drive assembly includes a drive rod, a driver releasably coupled to the drive rod, and a constant force spring which urges the drive rod towards the syringe assembly. The spring first urges the coupled drive rod and driver along the axis of the device, causing the skin to be penetrated by the needle of the syringe assembly. The drive rod is then decoupled from the driver. The spring continues to urge the drive rod in the axial direction, whereby the drive rod engages a piston in the syringe assembly and causes the displacement of the material therein.Type: GrantFiled: February 2, 1994Date of Patent: December 26, 1995Assignee: Becton, Dickinson and CompanyInventors: Ralf V. Bitdinger, Jean-Pierre Grimard, Bernard Sams, Donald D. Solomon
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Patent number: 5330430Abstract: A combination retractable syringe and injector enclosure are disclosed. A hypodermic syringe is placed into the injector enclosure and attached to a spring-loaded plunger. The plunger terminates in a tubular case that houses a coil spring and extends out from one end of the injector enclosure. An empty syringe may be filled by loading the injector with the empty syringe, engaging the plunger with the empty syringe, positioning a canula or needle of the syringe for collecting a fluid, and then withdrawing the case and plunger from the end of the injector enclosure. This causes the syringe to pull fluid from the canula and into the body of the syringe. In an alternate use, a fluid in a full syringe is dispensed by loading the injector enclosure with the full syringe, engaging the plunger with the full syringe, positioning the canula for injection, and then pushing the case into the injector enclosure.Type: GrantFiled: December 6, 1993Date of Patent: July 19, 1994Inventor: Robert J. Sullivan
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Patent number: 5328477Abstract: A liquid infusion system includes a flexible, flat, collapsible bag for storing liquid. An outlet communicates with the bag and a valve is used to control liquid outflow through the outlet tube. A rigid housing encloses the bag with the outlet tube projecting therefrom. A spring biased rigid pivot plate is positioned within the housing. The plate exerts pressure on the bag, tending to urge the bag toward a flat collapsed position and to expel liquids through the outlet when any liquid is present in the bag. Spring members are positioned in wells formed in the housing and the plate. The spring members exert a force against the plate.Type: GrantFiled: June 21, 1993Date of Patent: July 12, 1994Inventor: Phillip M. Sitko
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Patent number: 5300030Abstract: An injection device has a needle (22) which, when the device is operated, is first caused to project, then liquid is forced out through it, and finally the needle is automatically retracted. The needle (22) extends forwardly from a capsule (18) that can slide longitudinally within a barrel-like body (1), a relatively weak spring (19) normally maintaining the capsule and needle retracted. A more powerful spring (14) acts oppositely on a plunger (26) which, when released, shoots the capsule forward by acting on the liquid therein, and then forces the liquid out through the projecting needle (22). At the end of the forward stroke the plunger (26) and capsule (18) are decoupled and the weak spring (14) returns the exhausted capsule and its needle to the retracted position.Type: GrantFiled: May 29, 1992Date of Patent: April 5, 1994Assignee: Owen Mumford LimitedInventors: David D. Crossman, Jeremy Marshall, Ernest J. Mumford
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Patent number: 5273544Abstract: The present invention relates to an injection device for the automatic injection of at least one injection liquid, comprising an assembly of a discharge mechanism, a cartridge holder and a cartridge slidably accommodated in the cartridge holder, the discharge mechanism comprising an outer sleeve wherein the cartridge holder is slidably adapted. A protective cover is provided on the front of the device, covering the front portions of the cartridge holder and the outer sleeve in such a manner, that unintentional backward movement of the cartridge holder in the outer sleeve, resulting in activation of the device, is prevented.Type: GrantFiled: June 10, 1992Date of Patent: December 28, 1993Assignee: Duphar International Research B.V.Inventor: Gillis P. van der Wal
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Patent number: 5267963Abstract: This invention relates to an automatic injection device which, upon activation by the user, automatically extends a syringe with needle, delivers medication through the needle, and retracts the needle, thus keeping the needle hidden from view.Type: GrantFiled: August 21, 1992Date of Patent: December 7, 1993Inventor: Nicholas Bachynsky
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Patent number: 5248300Abstract: An ambulatory infusion system includes a spring-pressurized reservoir to facilitate portable use of the system. The system includes a liquid-filled flexible container, and a pair of opposed platens between which the flexible container is removably positionable. Energy-storing, clip-like biasing springs act against the platens to urge them toward each other, thereby effecting pressurization of the liquid within the container. A tubing set of the system preferably includes a non-adjustable flow restrictor, which may be sized for relatively low flow rates to permit the system to be used for catheter patency maintenance.Type: GrantFiled: December 16, 1991Date of Patent: September 28, 1993Assignee: Abbott LaboratoriesInventors: Peter L. Bryant, Lois L. Caron, Nicolaos A. Drivas, Richard W. Grabenkort, William L. Rudzena
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Patent number: 5211626Abstract: Medical infusion apparatus comprises a housing in which a standard flexible liquid reservoir is disposed. A constant-force spring applies pressure to the reservoir to force liquid out of the reservoir and along a conduit to a patient. The spring is energized by the opening of a lid of the housing which permits replacement of the reservoir.The liquid flowing out of the reservoir passes through a molded conduit part which is configured so that it is positioned at a predetermined location with respect to a flow monitor. The flow monitor injects a pulse of heat, and detects the rate at which the heat pulse travels along the conduit. A microprocessor uses the sensed flow rate to control a stepper motor which regulates fluid flow by squeezing the conduit via a spring-biased member. The apparatus has active and standby modes in which the monitor is operated respectively more and less frequently.Type: GrantFiled: December 17, 1990Date of Patent: May 18, 1993Assignee: Product Innovation Holdings Ltd.Inventors: Peter Frank, Terence G. Giles
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Patent number: 5114406Abstract: To permit accuracy presetting of a dose for an injection to be ejected from an ampule (12) containing more fluid medication than the dose requires, a plunger (18) which is telescopically received within a tubular element (77) is movable against the customary piston (17) in the ampule for a distance which depends on the extent of telescopic insertion of the plunger stem (18") within the tubular element (77). This extent can be set by a rotary knob or sleeve (56, 65) which rotates the tubular element with respect to the plunger (18); the plunger and tubular element are coupled together by a steeply pitched spiral thread (76), thereby controlling the extent of projection of the combined injection dosing arrangement of plunger (18) and plunger length setting mechanism (77), and hence controlling the amount of medicinal fluid expelled through an injection needle (16) coupled to the ampule (12) at the end of the injection device.Type: GrantFiled: January 18, 1990Date of Patent: May 19, 1992Assignee: Wilhelm Haselmeier GmbH & Co.Inventors: Jochen Gabriel, Herbert Bechtold, Gerhard Hambrecht, Klaus Nothdurft
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Patent number: 5102393Abstract: An autoinjector converted from an intramuscular to a subcutaneous mode of injection comprising a housing having a medicament cartridge assembly mounted within the housing means in a storage position for movement out of the storage position and a releasable stressed spring assembly for moving the medicament cartridge assembly means out of the storage position. The stressed spring assembly is operable in response to a manual actuating procedure which does not require compression of the subcutaneous tissue to effect an intramuscular mode of injection by moving the hypodermic needle of the cartridge assembly outwardly of the housing into the muscle tissue at the injection site of a user and a major portion of the liquid medicament of the cartridge assembly outwardly through the hypodermic needle into the muscle tissue of the user.Type: GrantFiled: July 17, 1989Date of Patent: April 7, 1992Assignee: Survival Technology, Inc.Inventors: Stanley J. Sarnoff, Claudio Lopez
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Patent number: 5085641Abstract: A stressed spring assembly for providing an operative stroke in cooperating relation with a medicament cartridge assembly of an auto-injector so as to inject a liquid medicament of the medicament cartridge assembly through a hypodermic needle of the medicament cartridge assembly into an injection site of the user. The stressed spring assembly includes a cap structure serving the plural purposes of (1) facilitating the securement of the cap structure and remainder of the auto-injection with the user's pocket, (2) alleviating the likelihood of an unwanted release of the releasable mechanism of the stressed spring assembly with a resultant unwanted movement of the hypodermic needle and an unwanted movement of the liquid medicament outwardly of the hypodermic needle by requiring two different manual movements for its removal, and (3) protecting against an unwanted contact with the hypodermic needle while in extended operative position after withdrawal from the injection site.Type: GrantFiled: April 12, 1990Date of Patent: February 4, 1992Assignee: Survival Technology, Inc.Inventors: Stanley J. Sarnoff, Claudio Lopez, N. Lawrence Dalling
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Patent number: 5085642Abstract: An autoinjector particularly suited to be carried on the person of a user comprising a housing defining an exterior configuration of a size and shape approximately the same as that of a conventional fountain pen including a housing body assembly of elongated generally cylindrical configuration and a separate housing cap structure of elongated generally cylindrical configuration having an elongated clip thereon. The housing cap structure is detachably secured to the housing body assembly in open ended telescopic relation with an opposite end portion thereof preferably by a childproof connection. A medicament cartridge assembly is mounted in a storage position within a forward end of an interior chamber within the housing body assembly and a releasable stressed spring assembly is carried by the housing body assembly adjacent the rearward end thereof.Type: GrantFiled: July 17, 1989Date of Patent: February 4, 1992Assignee: Survival Technology, Inc.Inventors: Stanley J. Sarnoff, Claudio Lopez
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Patent number: 5074843Abstract: A device for subcutaneous injection without a needle comprising an injection head (12) including a plurality of injection holes (38) having a diameter of less than about 100 microns, these holes being parallel to one another and being formed at the ends of larger-diameter oblique cylindrical ducts (42) made through the thickness of the injection head.Type: GrantFiled: July 2, 1990Date of Patent: December 24, 1991Inventors: Tino Dalto, Claude Laruelle
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Patent number: 5071353Abstract: The invention relates to a training device for an automatic injector. The device comprises a cylindrical outer sleeve in the rear portion of which a discharge mechanism is connected and in the front portion of which a holder intended for accommodating a punch member is incorporated so as to be locked against forward movement. The discharge mechanism comprises a plunger, a coil spring which acts on the plunger, a locking device and a safety member. The holder for the punch member comprises a sleeve-like rear portion which is open at each end. The punch member is accommodated in the holder such that its rear end at least substantially engages the front end of the plunger, and such that the front prod-shaped end portion which has dimensions such that it can pass through the central aperture in the nose portion of the holder outwards, is present within the holder prior to use of the device. The device further comprises auxiliary means for making the device ready for reuse.Type: GrantFiled: October 10, 1990Date of Patent: December 10, 1991Assignee: Duphar International Research B.V.Inventor: Gillis P. van der Wal
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Patent number: 5042977Abstract: An injection device can be loaded by the user only when in the zero position. This reminds even forgetful patients to readjust the dose before the injection and is of great help to blind patients.Type: GrantFiled: November 3, 1989Date of Patent: August 27, 1991Assignee: Wilhelm Haselmeier GmbH & Co.Inventors: Herbert Bechtold, Peter Kinast
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Patent number: 5037306Abstract: The invention relates to a training device for an automatic injector, comprising a cylindrical outer sleeve, in the rear portion of which a discharge mechanism is connected and in the front portion of which a holder for a punch member is accommodated so as to be locked against forward movement. The discharge mechanism comprises a plunger, a coil spring which acts on the plunger, a locking device and a safety member. The holder for the punch member comprises a sleeve-like rear portion which is open at each end. The punch member is accommodated in the holder so that the front prod-shaped end portion, which has such dimensions that it can pass throuogh the central aperture in the nose portion of the holder outward, is present inside the holder prior to use of the device.Type: GrantFiled: October 10, 1990Date of Patent: August 6, 1991Assignee: Duphar International Research B.V.Inventor: Hendrik A. van Schoonhoven
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Patent number: 5026349Abstract: A medical injector apparatus includes a syringe having a barrel with a lateral projection, a needle, a plunger in the barrel having a portion extending from the barrel opposite the needle.Type: GrantFiled: February 16, 1990Date of Patent: June 25, 1991Assignee: Autoject Systems Inc.Inventors: William B. Schmitz, William L. Schmitz
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Patent number: 4966585Abstract: Apparatus for infusion of a solution into a catheter or the like, the apparatus including a syringe with an administration set having a cup-shaped member configured for selective interlocking engagement with the syringe. The syringe includes a piston member and a coil spring within the bore having a first end urging against the piston. A separable handle member has a shaft axially positionable within the bore, with a reduced diameter threaded end configured for threadably engaging an aperture in the piston. A spring retaining cup within the bore acts against the other end of the spring, with the cup having a central aperture of a dimension sufficient for passage therethrough of the reduced diameter end of the shaft of the handle. Coupling of the handle to the piston compresses the spring via the cup.Type: GrantFiled: May 31, 1988Date of Patent: October 30, 1990Inventor: Ronald J. Gangemi
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Patent number: 4950265Abstract: The arming device for use in manipulating with one hand a medical instrument comprises first and second telescoping members. The instrument members are longitudinally movable relative to one another, and the device comprises an arcuate flexible member having a forward portion and a rearward portion with means at the forward portion for engaging the first member of the instrument and means at the rearward portion for engaging the second member whereby squeezing of the flexible member laterally toward the instrument causes the first and second telescoping members to move longitudinally away from each other thereby to cause arming or operation of the instrument.Type: GrantFiled: October 17, 1988Date of Patent: August 21, 1990Assignee: Hart Enterprises, Inc.Inventor: Glenn N. Taylor
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Patent number: 4902279Abstract: A safety injector, primarily for self-administered medicaments, is adapted to hold a charged hypodermic syringe and its needle with the needle in a protected retracted position. When a trigger member of the injector is pressed against the skin of the patient, the needle is exposed for producing shallow penetration of the skin, then a plunger actuator is released for producing a forward movement of the syringe a limited distance to cause full penetration by the needle and a coordinated forward movement of the syringe plunger to force medicament from the syringe through the needle in a "tracked injection." A safety mechanism prevents release of the plunger actuator unless the syringe is fully seated within the injector.Type: GrantFiled: October 5, 1988Date of Patent: February 20, 1990Assignee: Autoject Systems Inc.Inventors: William B. Schmidtz, William L. Schmitz
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Patent number: 4850971Abstract: This invention is an infusion pump utilizing a linear roller driven by a one or more constant force springs in combination with changeable flow regulating needles to provide a constant flow, gravity independent device. The spring constant is chosen so that infusion substantially decreases should the infusion needle become dislodged from the vein and come to rest in the surrounding tissue. Also, there is a means for introduction of an anticoagulant to maintain vein access if a delay is encountered in replacement of the infusion bag.Type: GrantFiled: February 23, 1988Date of Patent: July 25, 1989Assignee: Triangle Research and Development CorporationInventor: David P. Colvin
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Patent number: 4850967Abstract: Portable endermic injector of a mechanical type which comprises an aspiration and containment chamber, an assembly (12) to aspirate and to store, a cocking and trigger assembly (13) and an assembly (14) to read the quantity aspirated. A containment assembly (11) comprises the aspiration and containment chamber and a piston (19) and is screwed onto a frontal container (15). The assembly (12) to aspirate and to store energy comprises apparatus to regulate the pre-loading of a spring assembly (28) which includes spacer rings (226) and apparatus (15-23) having variable axial reciprocal positions. The reader assembly (14) comprises a threaded portion (46) and a slider (47) cooperating with a graduated area (50).Type: GrantFiled: June 15, 1987Date of Patent: July 25, 1989Assignee: SICIM SpAInventor: Pietro Cosmai
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Patent number: 4842576Abstract: A system for generating substantially constant fluid pressure is provided for forcing fluid from a variable volume container. The system includes a roller that rotates in response to a constant applied torque to force fluid from the flexible container under a substantially constant pressure. Two spaced apart parallel rollers can exert force on both sides of the container.Type: GrantFiled: October 15, 1986Date of Patent: June 27, 1989Assignee: Baxter International Inc.Inventors: Michael J. Lysaght, Daniel R. Boggs, Philip L. Ritger
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Patent number: 4820286Abstract: The invention relates to an automatic injector for injecting one or more injection liquids, comprising an assembly of a discharge mechanism, a cartridge in a cartridge holder, and an outer sleeve which is telescopically slidable around the cartridge holder, which cartridge comprises a barrel, in the barrel a piston and a number of separating stoppers equal to one less than the number of injection liquids, a needle holder with injection needle and optionally a by-pass for injection liquid. The injector is suitable for accommodating a solid and a solvent therefor, and for that purpose comprises a passable stopper between solid and solvent and a solvent by-pass in the barrel wall or in the passable stopper, in which, by a single or repeated operation of telescoping external parts of the injector solvent can pass the passable stopper and can reach the solid, as a result of which the injector can be made ready for use.Type: GrantFiled: May 12, 1987Date of Patent: April 11, 1989Assignee: Duphar International Research B.V.Inventor: Gillis P. van der Wal
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Patent number: 4795433Abstract: A method of treating a patient with liquid medicament under circumstances where intravenous injection is not practical but the fast response time of an intravenous injection is desirable, including the treatment of individuals undergoing heart attack symptoms with t-PA.Type: GrantFiled: March 31, 1988Date of Patent: January 3, 1989Assignee: Survival Technology, Inc.Inventor: Stanley J. Sarnoff
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Patent number: 4781688Abstract: A dispensing device for a liquid medicament has a cylindrical support formed on a base which receives an application part fitted into this support and costituting a projection from a cover. An annular reservoir braced against the support is pressed inwardly by a prestressed annular body which can be formed integrally with the reservoir of silicone rubber to drive a liquid medicament through the passage formed in the application part into the body at a constant rate.Type: GrantFiled: April 6, 1987Date of Patent: November 1, 1988Assignee: Herwig ThomaInventors: Herwig Thoma, Michael Krotlinger
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Patent number: 4781689Abstract: A housing having exterior lateral side walls, top and bottom side walls and a single internal wall running adjacent to a lateral side wall. The housing defines an internal rectangular compartment and a parallel side track between the adjacent internal and external walls. A collapsible bag filled with liquid and a slide member, actuable by a constant torque spiral spring are located in the compartment. The slide member has a boss fitting and cooperating with the track to allow the slide member to freely slide without a rotative component under action of the spring.Type: GrantFiled: November 13, 1986Date of Patent: November 1, 1988Inventors: Andrew Sealfon, Carl Yurdin
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Patent number: 4772263Abstract: An implantable infusion pump (20) for infusing drugs or other chemicals or solutions into the body. A flexible spring diaphragm (25) forms an outer back wall portion (26) of a housing (22) of the infusion pump (20). The spring diaphragm (25) applies substantially constant force over a range of displacement and communicating internal body pressure to the drug chamber (30) so as to maintain a substantially uniform pressure difference between the drug chamber (30) and the internal body pressure.Type: GrantFiled: September 23, 1987Date of Patent: September 20, 1988Assignee: Regents of the University of MinnesotaInventors: Frank D. Dorman, Henry Buchwald
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Patent number: 4741736Abstract: A cartridge, a control system and an infusion pump provide an infusion system. The cartridge contains one or more flexible compartments and pressure roller for squeezing fluid from the compartments. When there is a plurality of fluid compartments in the cartridge, a multilumen connector is provided on the cartridge so that it may be connected to a single multilumen catheter. The control system monitors the volume of fluid which is expelled from the fluid filled compartments during the infusion process. Any errors in rate or volume are continually fed back to the infusion pump. Errors exceeding allowable limits cause adjustment to correct for the error in volume so that over a long duration information process desired dosage is infused at an accurately maintained infusion rate. The infusion pump is provided with a constant force spring connected to a sliding member.Type: GrantFiled: December 10, 1986Date of Patent: May 3, 1988Assignee: I-Flow CorporationInventor: Eric W. Brown
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Patent number: 4718893Abstract: An implantable infusion pump (20) for infusing drugs or other chemical or solutions into the body. A movable diaphragm (26) forming a variable volume drug chamber (22). A fluid piston (32) opposing the force exerted by the diaphragm (26) on the drug solution in the drug chamber (22). The pressure of the fluid piston (32) being controlled by a regulator (33) providing a reference pressure and in fluid communication with the fluid piston (32). The regulator (33) reducing the fluid pressure of the piston fluid (32) as drug solution is expelled from the drug chamber (22) so as to maintain a constant pressure differential between the drug chamber (22) and an infusion site in the body. The implantable infusion pump (20) being readily adaptable to variable or electronic flow control.Type: GrantFiled: February 3, 1986Date of Patent: January 12, 1988Assignee: University of MinnesotaInventors: Frank D. Dorman, Henry Buchwald
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Patent number: 4596558Abstract: A pulsed liquid injection device for injection of predetermined doses of medication at predetermined intervals of time is described. A bag containing medication is maintained under pressure and is connectable via a three way valve, operable by means of an electronic timing device, to a second pressurized metering container which is smaller than the bag containing the medication. The pressure in the bag is higher than that of the metering device and the metering container is always at a pressure required for injection. The timing device operates the valve at intervals to (a) charge the metering container from the bag and (b) inject the charge in the metering container into the patient. The valve includes a blanking device to eliminate the possibility of injecting the patient directly from the bag.Type: GrantFiled: September 13, 1985Date of Patent: June 24, 1986Assignee: Queen's University at KingstonInventors: Timothy J. N. Smith, Alois J. van Eyken
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Patent number: 4578060Abstract: A device for removing fluids from a wound includes a housing and a resilient bellows inside the housing. The bellows can be collapsed and retained in a collapsed or activated state. Upon release from its activated state, the bellows is expanded so as to create a negative pressure therein whereupon fluids are automatically drawn into and collected within the bellows. Preferably the bellows is expanded by a variable force ribbon spring so that the resultant or combined restoring force provided by the resilient bellows and the variable force ribbon spring allows for the creation of a substantially constant level of negative pressure within the bellows so as to provide for a substantially constant level of suction of the device throughout the range of evacuation of fluids therein. The housing is preferably transparent with graduations provided thereon permitting the visible inspection and measurement of the fluids collected therein. A method for operating the device is also disclosed.Type: GrantFiled: July 20, 1983Date of Patent: March 25, 1986Assignee: Howmedica, Inc.Inventors: Charles M. Huck, Edward W. Larrabee
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Patent number: 4557728Abstract: Involved is a device, noteworthy by its compact construction, portability and use of a cooperating pair of constant torque springs to dispense liquid under a uniform force, in which any binding in the slide that is urged through movement by the torque springs is obviated, so that the slide tracks properly during liquid-dispensing service of the device.Type: GrantFiled: April 16, 1984Date of Patent: December 10, 1985Assignee: Repro-Med Systems, Inc.Inventors: Andrew Sealfon, Carl Yurdin
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Patent number: 4530695Abstract: An injector to inject liquid into an animal, said injector being of generally cylindrical configuration and having a pre-loadable piston and cylinder which when operated eject liquid through a needle of the injector, said injector having a trigger movably mounted at one end, which trigger selectively permits relative movement of the piston and cylinder to eject liquid from within the injector.Type: GrantFiled: December 19, 1983Date of Patent: July 23, 1985Assignee: N.J. Phillips Pty. LimitedInventors: Ian R. Phillips, Mervyn F. Reynolds, Robert H. Lodge
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Patent number: 4504267Abstract: To replace the usual gravity apparatus for intravenous injection of fluid in the body, there is provided a portable casing into which the usual collapsible liquid-containing flask is placed between two separate panels, one or both of which are movable toward and away from the other. The separation of the plates is against the force of prestressed torsion springs and these springs force the plates together toward a closed position when they are released after the flask has been placed between them to apply pressure to the flask and expel the liquid from the flash through a flexible tube having a discharge terminal. An actuating extension attached to the movable plate or plates is arranged to releasably hold them in separated positions when a flash is being removed or inserted between them. A garment is provided in which this apparatus may be retained when the patient is ambulatory.Type: GrantFiled: November 28, 1980Date of Patent: March 12, 1985Inventors: William H. Parmelee, Roger D. Sutton
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Patent number: 4484910Abstract: A dual mode automatic injector having a dual mode safety device for preventing the release of the stressed spring assembly except when it is desired to operate the medicament injecting assembly by the stressed spring assembly. The dual mode safety device comprises a first part including a pin portion disposed in a safety position extending through a central aperture in the rear wall of the housing assembly of the injector in release preventing relation with the stressed spring assembly for removal therefrom in response to a relative rearward movement with respect to the rear wall so as to permit an actuating movement to release the stressed spring assembly. The first part includes an automatic removal portion fixed to the rearward end of the pin portion.Type: GrantFiled: December 21, 1983Date of Patent: November 27, 1984Assignee: Survival Technology, Inc.Inventors: Stanley J. Sarnoff, George B. Calkins, Claudio Lopez
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Patent number: 4447232Abstract: A device, noteworthy by its compact construction, portability and use of a constant torque spring to dispense liquid under a uniform force, in which binding due to possible rotative movement in the slide that is powered by the torque spring is obviated, so that the slide tracks properly during liquid-dispensing service of the device, This is in contrast to torque spring-operated prior art devices in which special precautions were required to neutralize the turning movement unavoidably resulting when the torque spring assumed its characteristic helical coils during its functioning.Type: GrantFiled: May 21, 1982Date of Patent: May 8, 1984Assignee: Repro-Med Systems, Inc.Inventors: Andrew Sealfon, Carl Yurdin
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Patent number: 4403987Abstract: An injection aid for supporting a hypodermic syringe and for facilitating injection of the needle of the syringe into a limb. The apparatus includes a syringe supporting member and a pair of guide rods for supporting the syringe supporting member for slideable movement between a first position wherein a needle supported by the syringe supporting member is retracted from the limb and an injecting position. A pair of spaced apart generally parallel support rods are also provided. The rearward ends of the support rods being adapted to rest on the limb and are integrally joined to the guide rods and for supporting the guide rods. The support rods include forward ends for pinching flesh therebetween to cause the flesh adjacent the syringe needle to pucker.Type: GrantFiled: January 25, 1982Date of Patent: September 13, 1983Assignee: Gottinger Company, Inc.Inventor: John G. Gottinger