Electrical Energy Applicator Patents (Class 607/115)
  • Patent number: 8868205
    Abstract: A system and method for determining physiological parameters based on electrical impedance measurements is provided. One method includes obtaining electrical measurement signals acquired from a plurality of transducers coupled to a surface of an object and constructing a system matrix to define one or more relationships between the impedance measurement signals. The method also includes decomposing the system matrix to separate the electrical measurement signals.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: October 21, 2014
    Assignee: General Electric Company
    Inventors: Alexander Seth Ross, Jeffrey Michael Ashe
  • Patent number: 8868217
    Abstract: Devices and methods of treating a targeted body tissue by stimulating the body tissue with an electric current. In one embodiment, an apparatus includes an electrode carrier configured to be removably coupled to an interior surface of an orthosis. The electrode carrier includes a recess configured to matingly receive a portion of an electrode. The electrode carrier is electrically coupled to the electrode when the portion of the electrode is disposed within the recess. A connection member is electrically coupled to the electrode carrier and is configured to be releasably coupled to a surface of the orthosis. The electrode carrier is electrically coupled to the orthosis when the connection member is coupled to the orthosis. In some embodiments, the electrode carrier is configured to be removably coupled to the interior surface of the orthosis. In some embodiments, at least a portion of the electrode is constructed of an absorptive material.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: October 21, 2014
    Assignee: Bioness Neuromodulation Ltd.
    Inventors: Amit Dar, Mark Rubin, Shmuel Springer, Amir Cohen
  • Patent number: 8868189
    Abstract: A shielded three-terminal flat-through EMI/energy dissipating filter includes an active electrode plate through which a circuit current passes between a first terminal and a second terminal, a first shield plate on a first side of the active electrode plate, and a second shield plate on a second side of the active electrode plate opposite the first shield plate. The first and second shield plates are conductively coupled to a grounded third terminal. In preferred embodiments, the active electrode plate and the shield plates are at least partially disposed with a hybrid flat-through substrate that may include a flex cable section, a rigid cable section, or both.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: October 21, 2014
    Assignee: Greatbatch Ltd.
    Inventors: Robert A. Stevenson, Christine A. Frysz, Warren S. Dabney, Robert Shawn Johnson
  • Publication number: 20140309716
    Abstract: The invention provides a method of reducing an expected length of hospital stay of a patient during a recovery period after surgery, comprising repeated sessions of applying electrical stimulation (W, I) through one or more pairs of electrodes contacting a skin surface in the vicinity of the surgical site.
    Type: Application
    Filed: March 16, 2012
    Publication date: October 16, 2014
    Inventor: Joe Di Santo
  • Patent number: 8862243
    Abstract: Apparatus (20) is provided, including a bifurcation stent (50) comprising one or more electrodes (32), the stent (50) configured to be placed in a primary passage (52) and a secondary passage (54) of a blood vessel (30), and a control unit (34), configured to drive the electrodes (32) to apply a signal to a wall (36) of the blood vessel (30), and to configure the signal to increase nitric oxide (NO) secretion by the wall (36). Other embodiments are also described.
    Type: Grant
    Filed: July 25, 2006
    Date of Patent: October 14, 2014
    Assignee: Rainbow Medical Ltd.
    Inventor: Yossi Gross
  • Patent number: 8862242
    Abstract: One embodiment is a method of making a stimulation lead that includes providing a pre-electrode assembly comprising a plurality of segmented electrodes and a plurality of raised connectors. Each of the segmented electrodes is coupled to at least one other of the segmented electrodes by at least one of the raised connectors. The method further includes forming the pre-electrode assembly into a tube with the tube defining a longitudinal axis. Each of the raised connectors is disposed at a radius with respect to the longitudinal axis that is greater than a radius of any of the segmented electrodes with respect to the longitudinal axis. The method also includes forming at least a portion of a lead body around the segmented electrodes of the pre-electrode assembly; and grinding the tube comprising the pre-electrode assembly and portion of the lead body to remove the plurality of raised connectors leaving the plurality of segmented electrodes and the portion of the lead body.
    Type: Grant
    Filed: October 17, 2011
    Date of Patent: October 14, 2014
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Anne Margaret Pianca
  • Patent number: 8862246
    Abstract: Temporarily or permanently implantable medical device, having at least one longitudinally extended first electrical conductor having a functional lead, which is connected to a functional electrode pole for dispensing therapeutic signals or for detecting diagnostic signals, and including at least one second electrical conductor, which is coupled to the functional lead and is guided with it in a shared insulating sheathing, such that a coupling between the functional lead and the second electrical conductor is designed to input electromagnetic radiofrequency waves guided in the functional lead at least partially into the second electrical conductor.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: October 14, 2014
    Assignee: Biotronik SE & Co. KG
    Inventors: Klaus Bartels, Heinrich Buessing, Timo Frenzel, Gernot Kolberg, Michelle Maxfield, Ingo Weiss
  • Patent number: 8862247
    Abstract: The invention relates to a device for the electrostimulation therapy of the human body, comprising several electrodes (1) that contact the body surface and apparatuses (3-5) for applying voltage to the electrodes (1). According to the invention, the electrodes are arranged in a line and the apparatuses are provided to apply voltage to the electrodes (1) consecutively along the line.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: October 14, 2014
    Inventors: Erhard Schoendorf, Michael Schoendorf, Thomas Schoendorf
  • Patent number: 8855783
    Abstract: Apparatus is provided, including (1) an external device, configured for placement outside of a body of a subject and to sense a factor of the subject, and to generate a signal in response to the sensed factor, and (2) an implant, which comprises a wireless receiver for receiving the signal, and at least one electrode, the implant configured to drive the electrode to apply current to an aortic and/or vagal site of the subject in response to the signal.
    Type: Grant
    Filed: November 10, 2011
    Date of Patent: October 7, 2014
    Assignee: Enopace Biomedical Ltd.
    Inventors: Amir Dagan, Yossi Gross, Yotam Reisner, Offer Glasberg, Nitai Hanani, Gal Ariav, Oded Meiri
  • Patent number: 8855736
    Abstract: Transcutaneous safety electrode assemblies are described that can include a conducting electrode having a sharp end to penetration of the skin of a patient, and a shielding member that is deployable by a user so as to shield the sharp end of the electrode after the electrode is removed from the skin. The shielding member can be deployed by retracting the sharp end of the electrode a protective housing, assisted by spring force provided by the electrode wire so as to self-retract into the protective housing. The deployment and disengagement can be via push button action, and the electrode assembly can be self-retaining on the patient's skin while deployed.
    Type: Grant
    Filed: August 4, 2011
    Date of Patent: October 7, 2014
    Inventors: Richard A. Jaffe, Jaime R. Lopez, Alan Chris Allison
  • Patent number: 8855787
    Abstract: The present invention provides a method of stimulating an excitable tissue (e.g., in vitro, in vivo) with a primary electrical stimulus through a primary electrode at a primary stimulation frequency, to produce a propagating action potential in the excitable tissue. The invention is carried out by concurrently stimulating the excitable tissue with a secondary electrical stimulus through at least one secondary electrode at a secondary stimulation frequency. The primary and secondary stimulation frequencies are preferably different from one another. The secondary electrical stimulus preferably has an amplitude not more than one third that of the primary electrical stimulus. Preferably, propagation of the action potential in the excitable tissue is enhanced (e.g., when propagation of action potentials in the tissue is otherwise unstable, partially blocked, or fully blocked). Apparatus for carrying out the method is also described.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: October 7, 2014
    Assignee: The University of North Carolina Greensboro
    Inventors: Joseph M. Starobin, Vivek Varadarajan
  • Publication number: 20140296752
    Abstract: This disclosure provides non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries. In certain embodiments the method involves administering transcutaneous electrical spinal cord stimulation (tSCS) to the mammal at a frequency and intensity that induces the desired locomotor activity.
    Type: Application
    Filed: November 13, 2012
    Publication date: October 2, 2014
    Inventors: V. Reggie Edgerton, Yury Gerasimenko, Roland R. Roy, Daniel C. Lu
  • Patent number: 8849416
    Abstract: An implantable device (100) having an electronic component (110) and a biologic materials component (130). The biologic materials component has target cells in a matrix that interfaces the electronic component with the surrounding environment.
    Type: Grant
    Filed: May 4, 2005
    Date of Patent: September 30, 2014
    Assignee: University of Rochester
    Inventor: Spencer Rosero
  • Patent number: 8849368
    Abstract: Apparatus for capturing EEG signals comprising an implantable signal capture unit (34) connected to a proximal end of at least one implantable electrode (32) is implanted by passing a tubular guide sheath (24,26) along a subcutaneous path from an implantation site, passing the distal end of a said electrode through said guide sheath to bring said signal capture unit to said implantation site, and withdrawing said guide sheath from the electrode while progressively axially splitting the guide sheath to enable its removal. The signal capture unit may have a housing having at least two electrode contacts on its for capturing EEG signals in operative connection with circuitry within said housing for receiving said EEG signals and for wireless transmission thereof for reception at a location exterior to the body of the patient.
    Type: Grant
    Filed: January 2, 2009
    Date of Patent: September 30, 2014
    Assignee: Hypo-Safe A/S
    Inventors: Rasmus Madsen, Henning Beck-Nielsen
  • Patent number: 8849415
    Abstract: An implantable connector for use with a neurological device and a lead extension includes a male connector having a plurality of electrical contacts axially arranged along the connector, insulated from each other. The connector also includes a female connector having one or more channels axially disposed therein and a plurality of conductors axially arranged on the female connector. The plurality of conductors are electrically insulated from each other, and at least one indexing element is disposed adjacent to one or more of the channels. The indexing element allows the male connector to be received into the one or more channels in a defined orientation relative to the channel, thereby forming at least two electrical connections along two or more axial positions. Often the neurological device is a brain stimulating and recording lead. The male and female connectors are often fastened together with a screw or by twist-locking the two members together.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: September 30, 2014
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Purvis Bedenbaugh
  • Patent number: 8849414
    Abstract: An implantable paddle lead includes a paddle body coupled to a distal end of an elongated lead body. A plurality of contacts are disposed on a front surface of the paddle body. At least one manually bendable shape-retaining member is interconnected with the paddle body. The at least one shape-retaining member is formed from a deformable material that is stiff enough to maintain a given shape for at least one day. The at least one bendable shape-retaining member is interconnected with the paddle body such that bending the at least one shape-retaining member causes a corresponding bend of at least a portion of the paddle body in proximity to the at least one shape-retaining member.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: September 30, 2014
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Dongchul Lee
  • Publication number: 20140288613
    Abstract: A method for treating incontinence includes positioning a transcutaneous electrode on skin of a patient adjacent a stimulation site; inserting a leading end of a percutaneous needle electrode through the skin adjacent the stimulation site, the percutaneous needle electrode including a lead wire disposed opposite the leading end; securing a neurostimulator unit to the transcutaneous electrode such that the neurostimulator unit is electrically coupled to the transcutaneous electrode with no lead wire disposed between the neurostimulator unit and the transcutaneous electrode, the neurostimulator unit including a pulse generator; connecting the lead wire of the percutaneous needle electrode to the neurostimulator unit for electrically coupling the needle electrode to the neurostimulator unit; and activating the pulse generator such that current pulses traverse the stimulation site by passing between the transcutaneous electrode pad and the percutaneous needle electrode.
    Type: Application
    Filed: June 6, 2014
    Publication date: September 25, 2014
    Inventors: Brent D. Laing, John Green
  • Publication number: 20140275968
    Abstract: A surrogate implantable medical device includes a thermally conductive and electrically conductive housing. A header connector block includes a header block body, where the header block body is attached to the housing. At least one connector cavity is located within the header block body and configured to be attachable to an implantable lead. At least one conductive leadwire is disposed at least partially within the header block body having a first end and a second end. The at least one conductive leadwire's first end is electrically connected to the at least one connector cavity and the at least one conductive leadwire's second end is electrically connected to the housing. The housing does not contain active electronics.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: Greatbatch Ltd.
    Inventors: Robert A. Stevenson, Richard L. Brendel
  • Publication number: 20140277309
    Abstract: A method and apparatus for providing functional electrical stimulation to an individual for altering a mood or emotional parameter associated with a mood or emotional state is provided. The method involves providing functional electrical stimulation to facial muscles of the individual so as to elicit a detectable contraction in said muscles associated with a facial expression associated with a desired mood or emotional parameter.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 18, 2014
    Applicant: UNIVERSITY HEALTH NETWORK
    Inventors: Milos R. POPOVIC, Jose ZARIFFA, Sander L. HITZIG
  • Publication number: 20140277275
    Abstract: Presented herein is a shapeable coil cable for use in connection with an implantable medical device comprising first and second external components. The shapeable coil cable is a conformable and non-resilient member that is sufficiently pliable to accept a configuration set by a user and sufficiently rigid to retain the configuration set by the user.
    Type: Application
    Filed: March 12, 2013
    Publication date: September 18, 2014
    Inventors: Ferdie Josef Djunaedi, Tad Jurkiewicz
  • Patent number: 8834384
    Abstract: Apparatus is provided of locating the fossa ovalis in a patient by locating at least one of the His bundle, the plane of the interatrial septum, and the coronary sinus ostium in a patient, and thereafter locating the fossa ovalis on the basis of one or more predetermined distances between these locations. Software is also provided that can determine and display the location of the fossa ovalis in a patient based on predetermined distances between the locations. Such software can for example be provided within an electroanatomical system. Methods of determining the location of the fossa ovalis, performed by either a clinician or a central processing unit-controlled surgical system, are also provided and determined using predetermined measurements from defined locations. An apparatus for locating the fossa ovalis and performing a transseptal puncture is also provided.
    Type: Grant
    Filed: October 12, 2010
    Date of Patent: September 16, 2014
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventor: Subramaniam C. Krishnan
  • Publication number: 20140257437
    Abstract: Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and/or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and/or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.
    Type: Application
    Filed: May 23, 2014
    Publication date: September 11, 2014
    Applicant: ElectroCore, LLC
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 8831723
    Abstract: A cardiac medical device and associated method control delivery of dual chamber burst pacing pulses in response to detecting tachycardia. A number of cardiac cycles occurring in a first cardiac chamber are identified subsequent to the dual chamber pacing pulses. The number of sensed intrinsic events occurring in a second cardiac chamber during the first chamber cardiac cycles is determined as a number of second chamber events. The tachycardia episode is classified in response to the number of second chamber events.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: September 9, 2014
    Assignee: Medtronic, Inc.
    Inventors: Mark L. Brown, Troy Edward Jackson, Jeffrey M. Gillberg
  • Patent number: 8825181
    Abstract: A medical device lead includes an insulated lead body including at least one electrode, a helically coiled conductor electrically coupled to the at least one electrode, and one or more polymer coils formed coaxially with the helically coiled conductor. The helically coiled conductor includes a plurality of turns having a conductive coil pitch and including one or more conductive filars each having a conductive filar diameter. The one or more polymer coils provide at least about 25 ?N·m of torque transmitting capacity along a length of the medical device lead.
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: September 2, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Arthur J. Foster, Neranjan Persaud
  • Patent number: 8825165
    Abstract: A method for altering operation of a nerve related to a given body condition includes the steps of: laparascopically gaining access to the endopelvic area of the abdomen through the abdominal wall; implanting a multiple channel electrode through the access on endopelvic portions of at least one nerve of the sciatic nerve, the pudendus nerve, or both; and operating the electrode to electrostimulate the at least one nerve.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: September 2, 2014
    Inventor: Marc Possover
  • Patent number: 8821366
    Abstract: A cannula assembly, further comprising a cannula body for directing blood from the heart of a patient, having distal and proximal ends and a lumen therebetween. A tip coupled to the distal end of the body, the tip having an opening. A pump for drawing blood into the cannula assembly and dispensing the blood from the cannula assembly and into the patient circulatory system. The lumen of the cannula body further comprises a first inner diameter at the proximal end and a second inner diameter at the distal end, the first inner diameter being larger than the second inner diameter. A tapered portion defined as a decrease in inner diameter from the first inner diameter to the second inner diameter between the proximal and distal ends, the tapered portion configured to prevent cavitation of the blood within the cannula.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: September 2, 2014
    Assignee: Circulite, Inc.
    Inventors: Robert C. Farnan, Scott A. Olson, Elizabeth Jung, Andrew J. Dusbabek, Robert G. Hudgins
  • Publication number: 20140243942
    Abstract: A medical device lead connector includes two or more electrically conducting contact rings spaced apart by electrically insulating ceramic ring. An electrically insulating glass material fixes the two or more electrically conducting contact rings to the insulating ceramic ring in axial alignment.
    Type: Application
    Filed: May 5, 2014
    Publication date: August 28, 2014
    Applicant: MEDTRONIC, INC.
    Inventors: John E. Kast, Darren A. Janzig, Christopher J. Paidosh, Andrew J. Thom, Brad C. Tischendorf, Gerald G. Lindner
  • Publication number: 20140236272
    Abstract: A non-invasive electrical stimulator shapes an elongated electric field of effect that can be oriented parallel to a long nerve, such as a vagus nerve in a patient's neck, producing a desired physiological response in the patient. The stimulator comprises a source of electrical power, at least one electrode and a continuous electrically conducting medium in contact with the electrodes. The conducting medium is also in contact with an interface element that may conform to the contour of a target body surface of the patient when the interface element is applied to that surface. When the interface element is made of insulating (dielectric) material, and disclosed stimulation waveforms are used, the power source need not supply high voltage, in order to capacitively stimulate the target nerve.
    Type: Application
    Filed: February 24, 2014
    Publication date: August 21, 2014
    Applicant: Electrocore, LLC
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 8805501
    Abstract: An aspect of the present subject relates to an implantable medical system. An embodiment of the system includes a baroreflex stimulator, a myocardial infarction detector, and a controller. The baroreflex stimulator applies a baroreflex stimulation signal through an electrode. The myocardial infarction detector detects an event indicative of myocardial infarction, The controller is connected to the baroreflex stimulator and to the myocardial infarction detector, and is adapted to apply a baroreflex therapy in response to a detected event indicative of myocardial infarction. Other aspects are provided herein.
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: August 12, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventor: Imad Libbus
  • Patent number: 8800140
    Abstract: Some embodiments of the invention comprise a customizable multichannel microelectrode array with a modular planar microfabricated electrode array attached to a carrier and a high density of recording and/or stimulation electrode sites disposed thereon. Novel methods of making and using same are also disclosed.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: August 12, 2014
    Assignee: NeuroNexus Technologies, Inc.
    Inventors: Jamille F. Hetke, Daryl R. Kipke, David S. Pellinen, David J. Anderson
  • Publication number: 20140222124
    Abstract: Methods and devices for treating anaphylaxis, anaphylactic shock, bronchial constriction, and/or asthma include providing an electrical impulse to a selected region of the vagus nerve of a patient suffering from anaphylaxis to block and/or modulate nerve signals that would regulate the function of, for example, myocardial tissue, vasodilation/constriction and/or pulmonary tissue.
    Type: Application
    Filed: April 11, 2014
    Publication date: August 7, 2014
    Applicant: ElectroCore, LLC
    Inventors: Joseph P. Errico, Steven Mendez
  • Publication number: 20140222123
    Abstract: This disclosure provide a nanopillar electrode device, comprising a substrate patterned with a plurality of metal pads. The device may further comprise a plurality of nanopillars electrode arrays, wherein each nanopillar electrode array is attached to the substrate above a metal pad and electrically connected to the pad. The device may further comprise and a chamber surrounding the nanopillar electrodes, which can be used for culturing cells of interest for recording action potentials. The nanopillar electrode device may be configured to apply a voltage through the nanopillar electrodes from a voltage source. Nanopillar electroporation may be used to increase the permeability of cell membranes to allow intracellular recording. Also provided are methods of device fabrication, and methods of use.
    Type: Application
    Filed: January 30, 2014
    Publication date: August 7, 2014
    Inventors: Bianxiao Cui, Yi Cui, Ziliang Lin, Chong Xie
  • Publication number: 20140221809
    Abstract: A lead assembly includes a ring component having mechanical coupling features, and at least one polymer component mechanically coupled with the mechanical coupling features of the ring component. Elongate tubing is disposed over the polymer component and is secured with the polymer component.
    Type: Application
    Filed: March 24, 2014
    Publication date: August 7, 2014
    Applicant: Cardiac Pacemakers, Inc.
    Inventors: Paul E. Zarembo, Elliott Rodriguez Roman
  • Patent number: 8798750
    Abstract: In general, the disclosure describes techniques for detecting lead related conditions, such as lead fractures or other lead integrity issues. As described herein, delivering an electrical signal through selected electrodes may result in, reveal, or amplify noise if a lead related condition is present. A processor may detect electrical noise indicative of the lead related condition subsequent to the delivery of the electrical signal, and identify a lead related condition in response to detecting the noise.
    Type: Grant
    Filed: March 8, 2010
    Date of Patent: August 5, 2014
    Assignee: Medtronic, Inc.
    Inventors: Bruce D. Gunderson, Kevin A. Wanasek, Charles D. Swerdlow
  • Patent number: 8798770
    Abstract: A transvenously implantable medical device (TIMD) includes an electrical lead and a control module. The electrical lead includes one or more electrodes and is adapted for transvenous implantation. The electrical lead is also pre-biased to expand from a collapsed state to an expanded state to mechanically engage an internal wall of a blood vessel. The control module is secured to and in electrical communication with the electrical lead. The control module includes a signal management component and a power component disposed in a housing adapted for implantation into the blood vessel. The control module is adapted for at least one of stimulating and sensing a physiologic response using the one or more electrodes of the electrical lead.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: August 5, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventor: G. Shantanu Reddy
  • Patent number: 8798739
    Abstract: A patch for a therapeutic electrical stimulation device includes a shoe connected to the first side of the patch, the shoe including a body extending in a longitudinal direction from a first end to a second end, and having first and second surfaces, the first end of the shoe defining at least two ports, and the first surface of the shoe defining a connection member. The patch also includes at least one conductor positioned in the ports of the first end of the shoe. The shoe is configured for sliding insertion into a receptacle defined by a controller so that the conductor is connected to the controller to deliver electrical current from the controller, through the conductor, and to the electrodes, and the connection member is at least partially captured by a detent defined by the controller in the receptacle to retain the shoe within the receptacle.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: August 5, 2014
    Assignee: EMPI Inc.
    Inventors: Thomas Jerome Bachinski, Richard Paul Shindley, Dennis Lutz
  • Patent number: 8798771
    Abstract: Improving cardiac response in terms of pressure, ejected volume, and filling and ejection times by cardiac reverse remodelling, including temporary, occasionally harmful stimulation sequences. An original pacing configuration (a) is switched to a modified pacing configuration (b) in a direction opposite to that of an optimization of the hemodynamic parameters, to cause an immediate change in the response to controlled stimulation of the myocardium. This response is assessed based on: the maximum value (P (b, a)) achieved by the peak-to-peak (PEA (i)) of the first peak of endocardial acceleration (PEA) after a pacing configuration change, the mean PEA value (A (b, a)) after stabilization, the PEA variability (V (b, a)) around this average value, and the duration (T (b, a)) of stabilization after the pacing configuration change.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: August 5, 2014
    Assignee: Sorin CRM S.A.S.
    Inventors: Cyrille Casset, Melanie Heurteau
  • Patent number: 8798767
    Abstract: An implantable medical lead exhibits reduced heating under MRI conditions. The lead includes a multi-layer coil conductor including an inner coil layer, a middle coil layer disposed around the inner coil layer, and an outer coil layer disposed around the middle coil layer. Each of the coil layers is characterized by one or more of a filar thickness, a coil pitch, or a coil diameter configured such that the coil conductor exhibits a high inductance when exposed to MRI radiation. Each of the coil layers is electrically connected to the other coil layers to provide parallel conductive paths resulting in a coil conductor resistance suitable for defibrillation lead applications.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: August 5, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Arthur J. Foster, Christopher Perrey, Stephen Earl DeRoche
  • Patent number: 8798764
    Abstract: A physiological signal of a patient is sensed with sense electrodes symmetrically arranged relative to a stimulation electrode. In some examples, a member includes a plurality of relatively small electrodes that are configured to function as both sense and stimulation electrodes. One or more of the electrodes may be selected as stimulation electrodes and two or more different electrodes of the member may be selected as sense electrodes that are symmetrically arranged relative to the one or more selected stimulation electrodes. In some examples, a member includes a plurality of levels of segmented sense electrodes and a plurality of levels of stimulation electrodes. The levels of sense electrodes are arranged such that each level of stimulation electrodes is adjacent at least two levels of sense electrodes symmetrically arranged relative to the level of stimulation electrodes.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: August 5, 2014
    Assignee: Medtronic, Inc.
    Inventors: Gabriela C. Molnar, Scott R. Stanslaski
  • Patent number: 8792991
    Abstract: Techniques for modeling therapy fields for therapy delivered by medical devices are described. Each therapy field model is based on a set of therapy parameters and represents where therapy will propagate from the therapy system delivering therapy according to the set of therapy parameters. Therapy field models may be useful in guiding the modification of therapy parameters. As one example, a processor compares an algorithmic model of a therapy field to a reference therapy field and adjusts at least one therapy parameter based on the comparison. As another example, a processor adjusts at least one therapy parameter to increase an operating efficiency of the therapy system while substantially maintaining the modeled therapy field.
    Type: Grant
    Filed: January 22, 2009
    Date of Patent: July 29, 2014
    Assignee: Medtronic, Inc.
    Inventors: Martin T. Gerber, John C. Rondoni
  • Patent number: 8792998
    Abstract: Methods, systems and devices efficiently identify cardiac resynchronization therapy (CRT) pacing parameter set(s) that provide improved hemodynamic response relative to an initial CRT pacing parameter set, wherein each CRT pacing parameter set includes at least two CRT pacing parameters. User input(s) are accepted that specify a maximum amount of time and/or parameter sets that can be used to perform testing, and specify relative importance of parameters within the sets. Based on the accepted user input(s), there is a determination of how many different variations of each of the CRT pacing parameters can be tested, and based on this determination different CRT pacing parameter sets are selected and tested to obtain a hemodynamic response measure corresponding to each of the different sets tested. Additionally, one or more of the tested CRT pacing parameter sets, if any, that provide improved hemodynamic response relative to the initial CRT pacing parameter set is/are identified.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: July 29, 2014
    Assignee: Pacesetter, Inc.
    Inventors: Cecilia Qin Xi, Yasser Sowb
  • Patent number: 8792987
    Abstract: Deep brain electrodes are remotely sensed and activated by means of a remote active implantable medical device (AIMD). In a preferred form, a pulse generator is implanted in the pectoral region and includes a hermetic seal through which protrudes a conductive leadwire which provides an external antenna for transmission and reception of radio frequency (RF) pulses. One or more deep brain electrode modules are constructed and placed which can transmit and receive RF energy from the pulse generator. An RF telemetry link is established between the implanted pulse generator and the deep brain electrode assemblies. The satellite modules are configured for generating pacing pulses for a variety of disease conditions, including epileptic seizures, Turrets Syndrome, Parkinson's Tremor, and a variety of other neurological or brain disorders.
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: July 29, 2014
    Assignee: Greatbatch Ltd.
    Inventors: Robert A. Stevenson, Christine A. Frysz, Barry C. Muffoletto, Robert W. Siegler, Steven W. Winn, Thomas A. Skwara, Dominick J. Frustaci
  • Patent number: 8792995
    Abstract: Medical leads include a lumen body at an end of the lead, and the lumen body includes multiple filar lumens. The lumen body is joined to a lead body, and electrical connectors are longitudinally spaced along the lumen body. Filars within the filar lumens are directed through filar passageways within the lumen body to attach to the electrical connectors on the lumen body. The filar passageways may be aligned with the filar lumens, and slots within the electrical connectors may be aligned with the filar passageways to facilitate assembly. The lumen body may provide additional stiffness to the end of the lead where the lumen body is located to facilitate lead insertion into the medical device. The filar lumens of the lumen body may have a longitudinally straight configuration so that the portions of filars within the filar lumens are held in a longitudinally straight configuration.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: July 29, 2014
    Assignee: Medtronic, Inc.
    Inventors: Michael R. Klardie, Michael J. Kern, Brian T. Stolz, Marty D. Martens
  • Publication number: 20140207224
    Abstract: The present invention provides systems, apparatus and methods for applying electric current to neurons in the brain to treat disorders and to improve motor and/or memory functions in a patient. In a method according to the invention, an electrode is positioned adjacent to and spaced from the skin surface of the patient's head and an electric current is applied through the electrode to a target region in the brain to modulate one or more neurons in the target region. The electrode is housed within an enclosure and spaced from the skin surface so that the electrode does not directly contact the patient's tissue, which reduces the potential for collateral tissue damage or necrosis and shields the electrode from the patient's tissue which substantially inhibits Faradic products (e.g., H+, OH?, H2O2) of the electrode from reaching the target site.
    Type: Application
    Filed: March 24, 2014
    Publication date: July 24, 2014
    Applicant: ElectroCore, LLC
    Inventor: Bruce J. Simon
  • Patent number: 8788065
    Abstract: A method is provided for renal neuromodulation. One step of the method includes providing an expandable support member having a cuff-like configuration and including a main body portion (MBP). The MBP includes a lumen for engaging a wall of a blood vessel including a portion of a renal vasculature. At least one electrode connected with the MBP is arranged to selectively deliver electric current to a desired location. An insulative material is attached to at least a portion of the MBP. Next, the MBP is implanted extravascularly so that the MBP is in direct contact with a portion of the renal vasculature. At least one electrode is positioned substantially adjacent a desired location where modulation of the sympathetic nervous system (SNS) is effective to alter renal function. Electric current is then delivered to the at least one electrode to effect a change in the SNS.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: July 22, 2014
    Assignee: The Cleveland Clinic Foundation
    Inventors: Ali R. Rezai, Roy K. Greenberg, Milind Deogaonkar
  • Patent number: 8784291
    Abstract: A cannula assembly, further comprising a cannula body for directing blood from the heart of a patient, having distal and proximal ends and a lumen therebetween. A tip coupled to the distal end of the body, the tip having an opening. A pump for drawing blood into the cannula assembly and dispensing the blood from the cannula assembly and into the patient circulatory system. The lumen of the cannula body further comprises a first inner diameter at the proximal end and a second inner diameter at the distal end, the first inner diameter being larger than the second inner diameter. A tapered portion defined as a decrease in inner diameter from the first inner diameter to the second inner diameter between the proximal and distal ends, the tapered portion configured to prevent cavitation of the blood within the cannula.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: July 22, 2014
    Assignee: Circulite, Inc.
    Inventors: Robert C. Farnan, Scott A. Olson, Elizabeth Jung, Andrew J. Dusbabeck, Robert G. Hudgins
  • Patent number: 8788048
    Abstract: Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: July 22, 2014
    Assignee: SPR Therapeutics, LLC
    Inventors: Maria E. Bennett, Joseph W. Boggs, II, Warren M. Grill, John Chae
  • Patent number: 8788046
    Abstract: Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: July 22, 2014
    Assignee: SPR Therapeutics, LLC
    Inventors: Maria E. Bennett, Joseph W. Boggs, II, Warren M. Grill, John Chae
  • Patent number: 8788047
    Abstract: Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: July 22, 2014
    Assignee: SPR Therapeutics, LLC
    Inventors: Maria E. Bennett, Joseph W. Boggs, II, Warren M. Grill, John Chae
  • Patent number: 8788058
    Abstract: Implantable medical leads having resistance characteristics adapted to dissipate radio frequency (RF) electromagnetic energy during medical procedures such as magnetic resonance imaging (MRI) are disclosed. An illustrative medical device includes a lead having an inner electrical conductor operatively coupled to an electrode and a pulse generator, and one or more outer resistive shields that radially surround the inner conductor and dissipate RF energy into the surrounding body tissue along the length of the lead.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: July 22, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Yingbo Li, Masoud Ameri