Bacteria Or Actinomycetales; Media Therefor Patents (Class 435/252.1)
  • Publication number: 20140205693
    Abstract: The present invention relates to an extract from bacterial strains, such as Staphylococcus, Moraxella, Klebsiella, Streptococcus, and Haemophilus. The extract is useful as a treatment for indications such as respiratory disorders, compositions comprising the extract, and processes of making the extract from media that do not pose a risk of prion diseases.
    Type: Application
    Filed: March 20, 2014
    Publication date: July 24, 2014
    Applicant: OM PHARMA SA
    Inventors: Jacques Alain BAUER, Marco SALVAGNI, Jean-Pierre Leon VIGROUX, Laetitia CHALVET, Carlo CHIAVAROLI
  • Publication number: 20140206744
    Abstract: Provided are nucleic acid translators capable of carrying out logic operations with improved efficiency, maximized output and reduced off-target effects, in particular in a biological system. Methods of using these translators to transduce signal are also provided.
    Type: Application
    Filed: March 13, 2013
    Publication date: July 24, 2014
    Applicant: Emerald Therapeutics, Inc.
    Inventors: Daniel J. Kleinbaum, Brian M. Frezza, Brad Bond, Jonathan Leung, George W. Fraser
  • Publication number: 20140206063
    Abstract: An automated biological growth and dispensing apparatus utilizing a modular growing tank which is removable for replacement by another growing tank. Mechanisms for the delivery of air, water and/or nutrients are adapted to permit the growing tank to be readily coupled and uncoupled for easy and inexpensive replacement. Mechanisms for agitation may be integral and removable with the growing tank or may be adapted for a quick connection and disconnection with the growing tank. The growing tank may be disposable and each new growing tank may be provided as a sealed container including a starting amount of a biomass and/or nutrient.
    Type: Application
    Filed: March 14, 2014
    Publication date: July 24, 2014
    Inventor: Heiner Ophardt
  • Patent number: 8785160
    Abstract: The invention provides methods and pharmaceutical compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and pharmaceutical compositions for improving overall gastrointestinal health or for decreasing symptoms of lactose intolerance by administering to subject in need thereof a pharmaceutical composition comprising a prebiotic, optionally in combination with effective amount of a probiotic microbe or microbes.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: July 22, 2014
    Assignee: Ritter Pharmaceuticals, Inc.
    Inventors: Andrew J. Ritter, Dennis Savaiano, David Barnes, Todd Klaenhammer
  • Publication number: 20140199753
    Abstract: Novel strains and methods for their use are provided. Particularly, foods and other oral products or treatments containing sporulation-deficient Brevibacillus strain when administered to a subject can inhibit or reduce the number of pathogens in the subject and improve the health of the subject.
    Type: Application
    Filed: February 13, 2014
    Publication date: July 17, 2014
    Applicant: MYGALAXY Limited Company
    Inventor: Yiwei Jiang
  • Publication number: 20140194345
    Abstract: The present invention relates generally to novel depsipeptides, to methods for the preparation of these novel depsipeptides, to pharmaceutical compositions comprising the novel depsipeptides; and to methods of using the novel depsipeptides to treat or inhibit various disorders.
    Type: Application
    Filed: December 3, 2013
    Publication date: July 10, 2014
    Inventors: Aaron J. Peoples, Dallas Hughes, Losee Lucy Ling, William Millett, Anthony Nitti, Amy Spoering, Victoria Alexandra Steadman, Jean-Yves Christophe Chiva, Linos Lazarides, Michael Kenyon Jones, Karine Gaelle Poullenec, Kim Lewis
  • Patent number: 8771676
    Abstract: The present invention provides an agrochemically active microbial formulation comprising a combination of an agrochemically active microbe with a specified ester compound and a surfactant, the formulation exhibiting a stable pest controlling effect with no harmful effect on a plant and having highly stable viability of the agrochemically active microbe.
    Type: Grant
    Filed: June 22, 2007
    Date of Patent: July 8, 2014
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Shinya Kimura, Yoshiki Takashima, Takeshi Maruyama
  • Patent number: 8772013
    Abstract: A composition comprising intact minicells that contain a drug molecule is useful for targeted drug delivery. One targeted drug delivery method employs bispecific ligands, comprising a first arm that carries specificity for a bacterially derived minicell surface structure and a second arm that carries specificity for a mammalian cell surface receptor, to target drug-loaded minicells to specific mammalian cells and to cause endocytosis of the minicells by the mammalian cells. Another drug delivery method exploits the natural ability of phagocytic mammalian cells to engulf minicells without the use of bispecific ligands.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: July 8, 2014
    Assignee: Engeneic Molecular Delivery Pty Ltd
    Inventors: Himanshu Brahmbhatt, Jennifer MacDiarmid
  • Patent number: 8772015
    Abstract: A biofilter media has one or more of a set of desired physical characteristics. The set of physical characteristics includes a sphericity of 0.75 to 1, a particle size of 1 to 16 or 4 to 8 mm, a uniformity coefficient of 2 or less and a surface area of 800 to 2000 m2/m3 of media. The media is coated, supports microorganisms and is used to treat a waste gas stream.
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: July 8, 2014
    Assignee: Biorem Technologies Inc.
    Inventors: Hidayat Husain, Brian P. Herner
  • Publication number: 20140187818
    Abstract: The invention relates to a bacterial strain belonging to the genus Rhodococcus which is a producer of a nitrile hydratase. The invention also relates to a method for producing acrylamide by hydration of acrylonitrile using a biomass of the bacterial strain and to a method of culturing the bacterial strain.
    Type: Application
    Filed: December 24, 2013
    Publication date: July 3, 2014
    Inventors: Sergey Vladimirovich Kozulin, Tatiana Nicolaevna Kozulina, Alexey Sergeevich Kozulin
  • Publication number: 20140186385
    Abstract: The present invention discloses novel isolates of Neorickettsia risticii, compositions comprising such isolates, vaccines and methods for using such vaccines against Potomac Horse Fever.
    Type: Application
    Filed: December 10, 2013
    Publication date: July 3, 2014
    Applicant: Intervet Inc.
    Inventors: Lisa Purtle, Mark Mellencamp, Wendy Vaala
  • Publication number: 20140186475
    Abstract: The invention discloses a bacterial strain of non pathogenic Cobetia marina useful in aquaculture, corresponding to an isolated Cobetia marina strain, Gram negative, oxidase positive, deposited under registry number CECT N° 7764; grows with dibenzothiophene (DBT) as the only carbon source. Also disclosed is a method to obtain a biosurfactant surfactant extract comprising growing strain Cobetia marina (MM1IDA2H-1) CECT N° 7764 in a reactor with liquid growth medium from 24 to 48 hours at a temperature between 10 and 35° C., pH 6 to 8; constant stirring between 100 to 400 rpm and oxygen saturation between 10 to 21%; until obtaining a grown cell culture and extracellular products plus inorganic salts; separating the cells, lyophilizing supernatant, sieve the obtained powder and dry.
    Type: Application
    Filed: May 30, 2012
    Publication date: July 3, 2014
    Applicant: UNIVERSIDAD DE VALPARAISO
    Inventors: Miguel Alejandro Dinamarca Tapia, Juan Ricardo Ojeda Herrera, Claudia Jimena Ibacache Quiroga
  • Patent number: 8765445
    Abstract: The present invention provides an equol-producing lactic acid bacteria-containing composition comprising, as an essential component thereof, a lactic acid bacterial strain belonging to the genus Lactococcus having an ability to utilize at least one daidzein compound selected from the group consisting of daidzein glycosides, daidzein, and dihydrodaidzein to produce equol. Such a composition is effective for the prevention and alleviation of malaise inclusive of climacteric disturbance in middle-aged and elderly women for which no effective prophylactic method or alleviating means has heretofore been available.
    Type: Grant
    Filed: June 29, 2004
    Date of Patent: July 1, 2014
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Shigeto Uchiyama, Tomomi Ueno, Toshimi Suzuki
  • Patent number: 8765118
    Abstract: The present invention relates to a novel wild-type Lactococcus lactis subsp. cremoris bacteria strain with increased vitamin K2 production and mutants and variants thereof and methods for preparation of a fermented food or feed product enriched in vitamin K2 and a vitamin K enriched edible product for amelioration and/or prevention of vitamin K deficiency. The present invention also relates to the fermented food or feed product and the edible product obtainable by the methods herein and to the wild-type Lactococcus lactis subsp. cremoris bacteria strain for use in treatment and/or prevention of vitamin K deficiency in a mammal, such as a human.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: July 1, 2014
    Assignee: Chr. Hansen A/S
    Inventors: Christel Garrigues, Martin Bastian Pedersen
  • Patent number: 8765404
    Abstract: Some aspects of this invention relate to methods useful for the conversion of a carbon source to a biofuel or biofuel precursor using engineered microbes. Some aspects of this invention relate to the discovery of a key regulator of lipid metabolism in microbes. Some aspects of this invention relate to engineered microbes for biofuel or biofuel precursor production.
    Type: Grant
    Filed: March 2, 2011
    Date of Patent: July 1, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Gregory Stephanopoulos, Syed Hussain Imam Abidi
  • Patent number: 8765399
    Abstract: Disclosed are culture media, protocols and kits for diagnosis of toxigenic Clostridium difficile, where the culture medium comprises Cooked Meat Medium with glucose; yeast extract; taurocholate; cycloserine; and cefoxitin.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: July 1, 2014
    Assignee: Montefiore Medical Center
    Inventor: Paul Riska
  • Publication number: 20140178952
    Abstract: The invention provides a simple and effective method for improving acid tolerance of P. acdipropionici by adding arginine and/or aspartic acid to the culture medium. The acid tolerance of P. acdipropionici was improved by 60% and 20% respectively through adding arginine or aspartic acid into the culture medium. Consequently, PA production was improved by 36% and 26%, respectively. The maximal PA production was obtained by adding both 20 mM arginine and 20 mM aspartic acid. This method can be applied to large scale production of PA.
    Type: Application
    Filed: October 7, 2013
    Publication date: June 26, 2014
    Inventors: Jian Chen, Guocheng Du, Long Liu, Jianghua Li, Ningzi Guan
  • Publication number: 20140178970
    Abstract: An isolated microbial consortia is described. The consortia may include a first-bite microbial consortium that converts a starting hydrocarbon that is a complex hydrocarbon into two or more first-bite metabolic products. The consortia may also include a downstream microbial consortium that converts a starting hydrocarbon metabolic product into a downstream metabolic product. The downstream metabolic product has a greater mol. % hydrogen than the starting hydrocarbon. The first-bite microbial consortium or the downstream microbial consortium includes one or more species of Desulfuromonas.
    Type: Application
    Filed: October 8, 2013
    Publication date: June 26, 2014
    Applicant: Luca Technologies, Inc.
    Inventor: Gary Vanzin
  • Publication number: 20140178971
    Abstract: Bacteria that can use antibiotics as a carbon source are provided. Methods and bacteria useful for bioremediation are also provided.
    Type: Application
    Filed: December 27, 2013
    Publication date: June 26, 2014
    Inventors: George M. CHURCH, Gautam DANTAS, Morten O. SOMMER
  • Publication number: 20140178433
    Abstract: The antigenic mass of Leptospira cultures can be significantly increased, independent from any increase in biomass, by supplementing Leptospira cultures with a specific fatty acid: linoleic acid. This provides advantages in the production Leptospira antigens. Also this enables the production of improved Leptospirosis vaccines, that are safer and more effective.
    Type: Application
    Filed: December 16, 2013
    Publication date: June 26, 2014
    Inventors: Edwin Kets, Christian Theodoor Gerardus Smits, Henriette Adriaanse
  • Publication number: 20140178439
    Abstract: A method of preparing a capturing agent for a selected biopolymer or bioparticle, includes the steps of: a) selecting a desired biopolymer or bioparticle, and b) providing a support matrix modified to have, at predetermined conditions, such a net negative surface charge and net surface hydrophobicity in relation to the net negative surface charge and the net surface hydrophobicity of the selected biopolymer or bioparticle that the modified support matrix is capable of selective interaction and capture of the biopolymer or bioparticle through a resulting net hydrophobic interaction being the actual hydrophobic interaction minus the actual electrostatic repulsion. The use of such a capturing agent as a therapeutically active substance, as well as in chromatography and diagnosis are also disclosed.
    Type: Application
    Filed: July 20, 2012
    Publication date: June 26, 2014
    Inventor: Stellan Hjerten
  • Publication number: 20140178983
    Abstract: A heat exchanger system includes a heat exchanger having a body plate with a first side face and an opposing second side face, the body plate bounding a fluid channel disposed between the opposing side faces and extending between an inlet port and an outlet port, and a first side plate having an inside face. A flexible first bag includes of one or more sheets of polymeric material, the first bag bounding a fluid pathway that extends between a fluid inlet and a fluid outlet, the first bag being removably retained between the body plate and the first side plate so that at least a portion of the first bag rests against the first side face of the body plate when the fluid pathway of the first bag is filled with a fluid.
    Type: Application
    Filed: November 22, 2013
    Publication date: June 26, 2014
    Applicant: HYCLONE LABORATORIES, INC.
    Inventors: Clinton C. Staheli, Nephi D. Jones, Michael E. Goodwin
  • Publication number: 20140179942
    Abstract: The invention relates to a micro-organism comprising a hydrogenase enzyme system which is capable of converting carbon dioxide into formic acid and a second enzyme system which is capable of converting formic acid into aliphatic carboxylic acids having a chain length of five or more carbon atoms. Also described are various methods for producing oil, as well as other aspects of the invention.
    Type: Application
    Filed: July 13, 2012
    Publication date: June 26, 2014
    Applicant: VERDANT BIOPRODUCTS LIMITED
    Inventor: Irene Finnegan
  • Patent number: 8759494
    Abstract: The invention relates to antibodies to the tumor-associated antigen CD33 and to the use thereof for immunotargeting CD33-positive cells. The antibodies according to the invention are suitable for use in the field of medicine, pharmaceuticals, and biomedical research. According to the invention, the aim is achieved by means of novel anti-CD33 antibodies comprising the complementary determining regions (CDRs) defined in the claim. The antibodies according to the invention are characterized by a high affinity for human CD33, of the order of magnitude of 10?10 mol/l. The CDR sequences according to the invention are suitable in particular for producing recombinant fragments (such as scFv fragments or bispecific antibodies) and for immunotargeting, due to the high affinity thereof.
    Type: Grant
    Filed: September 22, 2010
    Date of Patent: June 24, 2014
    Assignee: GEMoaB Monoclonals GmbH
    Inventors: Michael Bachmann, Slava Stamova
  • Patent number: 8759021
    Abstract: Provided are a microorganism for use in quantification of homocysteine and methionine and a method of quantifying homocysteine and methionine in a sample by using the microorganism.
    Type: Grant
    Filed: May 20, 2010
    Date of Patent: June 24, 2014
    Assignee: Labgenomics Co., Ltd.
    Inventors: Hyun Gyu Park, Min-Ah Woo, Moon Il Kim, Sang-Joon Hwang, Dae-Yeon Cho
  • Patent number: 8759032
    Abstract: A genetically engineered strain WSJ-IA for producing isovaleryl spiramycin I. Also provided is a method for preparing the strain, including the steps of: (a) constructing a recombinant plasmid including a double gene ist-acyB2; (b) transforming the plasmid into an isovaleryl spiramycin I-producing strain to obtain the strain WSJ-IA. The level of isovaleryl spiramycin I produced by fermentation of the strain WSJ-IA is increased 1.7 times and the fermentation potency thereof increased 4.14 times in comparison with the strain exclusively including a single gene ist.
    Type: Grant
    Filed: July 21, 2011
    Date of Patent: June 24, 2014
    Assignee: Shen Yang Tonglian Group Co., Ltd.
    Inventors: Yiguang Wang, Yang Jiang, Shengwu Yang, Xiaofeng Zhao
  • Patent number: 8759069
    Abstract: Contamination was controlled in fermentations using Zymomonas mobilis as the biocatalyst, without negative impact on fermentation production, by the addition of hop acids. The effective concentration of hop acids was found to be dependent upon the type of fermentation medium used.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: June 24, 2014
    Assignee: E I du Pont de Nemours and Company
    Inventors: George C Fox, Maria C Leana, Brian G Lefebvre
  • Publication number: 20140170190
    Abstract: The present invention provides attenuated M. haemolitica strains that elicit an immune response in animal against M. haemolitica, compositions comprising said strains, methods of vaccination against M. haemolitica, and kits for use with such methods and compositions. The invention further provides multi-valent vaccines, which provide protective immunity when administered in an effective amount to animals susceptible to “shipping fever” or bovine respiratory disease.
    Type: Application
    Filed: November 8, 2013
    Publication date: June 19, 2014
    Applicant: MERIAL LIMITED
    Inventors: Russell F Bey, Paulraj Kirubakaran Lawrence, Randy R Simonson
  • Publication number: 20140171482
    Abstract: The present invention is directed to transfection complexes of rosette nanotubes and one or more nucleic acids.
    Type: Application
    Filed: January 3, 2012
    Publication date: June 19, 2014
    Applicants: RHODE ISLAND HOSPITAL, Brown University
    Inventors: Thomas J. Webster, Qian Chen, Yupeng Chen
  • Publication number: 20140170168
    Abstract: Provided are isolated high affinity entities which comprise an antigen binding domain which specifically binds a soluble T-cell receptor ligand comprising a two-domain beta1-alpha1 of a major histocompatibility complex (MHC) class II, wherein said antigen binding domain does not bind a complex comprising a four-domain alpha1-beta1/alpha2-beta2 MHC class II. Also provided are methods and kits using same for detecting and sequestering soluble two-domain T cell receptor ligands in a sample.
    Type: Application
    Filed: October 26, 2011
    Publication date: June 19, 2014
    Inventors: Yoram Reiter, Rony Dahan, Arthur A. Vandenbark
  • Publication number: 20140170637
    Abstract: Methods for aiding in the diagnosis of disorders including, but not limited to, PDDs (Pervasive Development Disorders), Dysautonomic disorders, Parkinson's disease and SIDS (Sudden Infant Death Syndrome). In one aspect, a diagnosis method comprises analyzing a stool sample of an individual for the presence of a biological marker (or marker compound) comprising one or more pathogens, which provides an indication of whether the individual has, or can develop, a disorder including, but not limited to, a PDD, Dysautonomia, Parkinsons disease and SIDS. Preferably, the presence of one or more pathogens is determined using a stool immunoassay to determine the presence of antigens in a stool sample, wherein such antigens are associated with one or more pathogens including, but not limited to, Giardia, Cryptosporidium, E. histolytica, C. difficile, Adenovirus, Rotavirus or H. pylori.
    Type: Application
    Filed: September 26, 2013
    Publication date: June 19, 2014
    Applicant: Curemark, LLC
    Inventor: Joan M. Fallon
  • Publication number: 20140162343
    Abstract: Novel strains and methods for their use are provided. Particularly, foods and other oral products or treatments containing sporulation-deficient Brevibacillus strain when administered to a subject can inhibit or reduce the number of pathogens in the subject and improve the health of the subject.
    Type: Application
    Filed: February 13, 2014
    Publication date: June 12, 2014
    Inventor: Yiwei Jiang
  • Publication number: 20140161781
    Abstract: The invention relates to a zinc-enriched biomass comprising living or subsequently killed micro-organisms, selected from the group consisting of Streptococcus thermophilus and Bifidobacterium animalis subsp. lactis and combinations thereof, a method for the manufacture of said zinc-enriched biomass, as well as food preparations, nutraceutic products, functional foods, cosmetic and cosmeceutic products, and food supplements, comprising the said biomass. Furthermore, new micro-organism strains are described which are able to concentrate zinc within the cell in very high amounts and therefore are particularly suitable for use in the method of the invention.
    Type: Application
    Filed: November 4, 2013
    Publication date: June 12, 2014
    Inventors: Alberto BENEDETTI, Francesco GIRARDO
  • Patent number: 8748154
    Abstract: The present invention relates to a Sphingomonas sp. MD2 strain (KCTC 11845BP), a composition including the strain for decomposing methane or odor-producing compounds, a biocover or biofilter including the composition, a method for decomposing methane or odor-producing compounds using the composition, a system for decomposing methane or odor-producing compounds using the biocover or biofilter, and the use of the strain for decomposing methane or odor-producing compounds. According to the present invention, methane and odor can be effectively removed concurrently, and thus the cost required for the separate treatment of methane and odor can be reduced, and methane and odor-producing compounds in landfills or the like can be effectively decomposed.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: June 10, 2014
    Assignee: EWHA University-Industry Collaboration Foundation
    Inventors: Kyung Suk Cho, Jung Hee Lee, Kyung Eun Moon, Tae Gwan Kim, Sang Hyon Lee
  • Publication number: 20140154218
    Abstract: According to the present invention, an anti-allergic agent is provided which includes a polysaccharide comprising galactose, glucose and rhamnose as constituents, or includes a microorganism belonging to a genus Bifidobacterium and extracellularly producing the polysaccharide. The anti-allergic agent of the present invention can be used in oral compositions and compositions for external application, and is suitable for use in products such as food products, pharmaceutical products, and cosmetics.
    Type: Application
    Filed: February 10, 2014
    Publication date: June 5, 2014
    Applicant: MORISHITA JINTAN CO., LTD.
    Inventors: Mamiko KOHNO, Shinichi KITAMURA, Aiko SHOJO
  • Publication number: 20140154217
    Abstract: New Lactococcus lactis strains, NRRL B-50571 and NRRL B-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides that reduce blood pressure, lower LDL-cholesterol (bad cholesterol) and present antioxidant properties for better cardiovascular health. These biologically active peptides may be produced within the food for the production of a food product, such as a functional food, or they may be produced from protein sources and subsequently added to a food as part of the formulation or as part of a food supplement or a pharmaceutical preparation.
    Type: Application
    Filed: September 27, 2012
    Publication date: June 5, 2014
    Applicants: CENTRO DE INVESTIGACION EN ALIMENTACION Y DESARROLLO, A.C. (CIAD)
    Inventors: BELINDA VALLEJO GALLAND, AARÓN FERNANDO GONZÁLEZ CÓRDOVA, JOSÉ CARLOS RODRÍGUEZ FIGUEROA
  • Publication number: 20140155586
    Abstract: A compound having a structure expressed by the following Structural Formula (1), tautomers thereof, or salts of the compound or the tautomers.
    Type: Application
    Filed: October 21, 2011
    Publication date: June 5, 2014
    Inventors: Masayuki Igarashi, Ryuichi Sawa, Yoshiko Homma
  • Patent number: 8741365
    Abstract: The present disclosure relates in one embodiment to a method of producing a fermented food, wherein a raw food material is combined with a starter culture for fermentation, wherein at least one microorganism of the genus Bacteroides and/or at least one microorganism having at least a cell surface structure which corresponds to a human carbohydrate structure is added. Further disclosed are processing aids and fermented foods containing respective microorganisms.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: June 3, 2014
    Assignee: Glycotope GmbH
    Inventors: Steffen Goletz, Philippe Ulsemer
  • Patent number: 8741622
    Abstract: The present invention relates in general to the field of Bifidobacteria. In particular, the present invention relates to the field of Bifidobacteria with a modulated stress resistance. One embodiment of the present invention is a Bifidobacterium with a constitutively modulated DnaK, GrpE and/or CIpB expression.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: June 3, 2014
    Assignee: Nestec S.A.
    Inventors: Bernard Berger, Enea Rezzonico, Fabrizio Arigoni
  • Publication number: 20140147907
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to proceed ethanol and/or butanol, e.g., by fermentation.
    Type: Application
    Filed: January 31, 2014
    Publication date: May 29, 2014
    Applicant: XYLECO, INC.
    Inventors: Marshall Medoff, Thomas Craig Masterman
  • Publication number: 20140144838
    Abstract: The present invention provides a bio-augmentation composition for improving the hydrocarbon degradation efficiency of effluent treatment plant for hydrocarbon degradation in wastewater generated from hydrocarbon processing industry and a method thereof. The composition comprises a synergistic combination of selective microorganisms to develop a consortium enabling effective degradation of hydrocarbons present in wastewater and converting thereof into harmless and environment friendly substances. The invention also provides for the said microorganisms and their isolations.
    Type: Application
    Filed: April 2, 2012
    Publication date: May 29, 2014
    Applicant: INDIAN OIL CORPORATION LTD.
    Inventors: Manoj Kumar, Mahendra Pratap Singh, Ashok Kumar Tiwari, Deepak Kumar Tuli, Ravinder Kumar Malhotra, Anand Kumar
  • Publication number: 20140147873
    Abstract: In various embodiments a system is provided that displays heterologous proteins on the surface of a Gram-positive microorganism. In certain embodiments the system displays proteins using a sortase transpeptidase to covalently anchor proteins to the cell wall of the microbe. Novel bacterial strains are provided to exploit this system to display cellulase enzymes and multi-enzyme complexes on the surface of Gram-positive microorganisms (e.g., Bacillus subtilis) through their non-covalent interaction with a scaffoldin protein that is covalently anchored to the cell wall by the sortase transpeptidase. The surface displayed protein complexes contain enzymes capable of degrading cellulose into its component sugars at accelerated rates as compared to solutions of purified enzymes.
    Type: Application
    Filed: February 29, 2012
    Publication date: May 29, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Robert T. Clubb, Timothy Anderson
  • Publication number: 20140147379
    Abstract: A method of treating a tumor in a subject, or reducing or preventing metastasis of a tumor in a subject, is provided comprising administering to the subject an amount of a bacteria labelled with, or comprising, one or more radionuclides so as to treat the tumor in the subject, or so as to reduce or prevent metastasis of the tumor in the subject. Radiobacteria-containing compositions and pharmaceutical compositions are also provided.
    Type: Application
    Filed: February 3, 2012
    Publication date: May 29, 2014
    Applicant: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Ekaterina Dadachova, Claudia Gravekamp, Arturo Casadevall
  • Patent number: 8734783
    Abstract: The present invention relates to a composition comprising probiotic bacteria for the treatment of pathologies associated with alterations of the immune system. In particular, the present invention relates to the use of selected probiotic bacteria for the preparation of a composition for the treatment of allergies, such as atopic dermatitis.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: May 27, 2014
    Assignee: Probiotical S.p.A.
    Inventors: Giovanni Mogna, Gian Paolo Strozzi, Luca Mogna, Lorenzo Drago
  • Patent number: 8735106
    Abstract: The present invention relates to a method of successively producing D-psicose from D-fructose or D-glucose by using a psicose-epimerase derived from Agrobacterium tumefaciens which is expressed in a food safety form.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: May 27, 2014
    Assignee: CJ Cheiljedang Corporation
    Inventors: Young Ho Hong, Jin Ha Kim, Sung Bo Kim, Jung Hoon Kim, Young Mi Lee, Seung Won Park
  • Patent number: 8735132
    Abstract: The invention relates to identification of mutations and genetic targets for enhanced L-tyrosine production, and bacterial strains capable of L-tyrosine production.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: May 27, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Christine Santos, Gregory Stephanopoulos
  • Patent number: 8734814
    Abstract: The present invention relates to recombinant strains of Vibrio spp, which are unable to utilize the amino sugar N-acetylglucosamine (GlcNAc) as a sole carbon source. This inability to utilize GlcNAc severely impairs the colonization property of the recombinants. The present invention also provides compositions comprising these recombinant strains for use in pharmaceuticals and in providing immunity.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: May 27, 2014
    Inventors: Asis Datta, Sumit Ghosh, Swagata Ghosh, Hanumantha Rao Kongara, Mohan Kamthan
  • Publication number: 20140141044
    Abstract: The present invention provides a novel cord colitis syndrome pathogen as well as a method for the discovery of novel viral, prokaryotic or eukaryotic genomes or genomic fragments using a sequencing-based methodology.
    Type: Application
    Filed: November 12, 2013
    Publication date: May 22, 2014
    Inventors: Ami S. Bhatt, Samuel S. Freeman, Chandra Sekhar Pedamallu, Francisco Marty, Matthew Meyerson
  • Patent number: 8728777
    Abstract: The present invention relates to novel stress-resistant bacteria and the uses thereof. More specifically, the invention relates to isolated stress-resistant bacteria having advantageous properties for the production of organic acids or alcohols in various culture conditions. The invention also relates to methods of producing organic acids or alcohols using said bacteria, particularly from biomass.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: May 20, 2014
    Assignees: Deinove, Centre Naitonal de la Recherche Scientifique, Universite Montpellier I
    Inventors: Jacques Biton, Cathy Isop
  • Patent number: 8728776
    Abstract: The invention relates to strains of bacteria of the genus Ochrobactrum, that can degrade polylactic acid. The invention also relates to an enzyme that can degrade polylactic acid, characterized in that it is produced by said bacteria strains according to the invention. The invention also relates to the applications of said bacteria strains and said enzyme that can degrade polylactic acid.
    Type: Grant
    Filed: October 1, 2010
    Date of Patent: May 20, 2014
    Assignees: Centre National de la Recherche Scientifique—CNRS, Universite de Poitiers
    Inventors: Thierry Ferreira, Willy Aucher