Abstract: A multi-dose injection syringe includes a syringe body for containing a medicine and a plunger moveable within the syringe body, from an injection start position, to eject medicine therefrom, the syringe further including a scale provided on one of the syringe body and the plunger, the scale providing a time ordered sequence of indicia and being configurable to align any one of the indicia with the injection start position, at least part of the syringe body being transparent such that the plunger's degree of progression through the syringe body, with respect to the time ordered sequence of indicia, is externally visible.

Abstract: An assembly for a drug delivery device is provided the assembly comprising a cartridge adapted and arranged to contain at least one dose of a drug, a bung being slidably arranged within the cartridge, a housing comprising a distal end and a proximal end, and a piston rod adapted and arranged for moving the bung in the distal direction with respect to the housing for dispensing a dose of the drug. The assembly further comprises a drive member and arranged for transferring movement to the piston rod for dispensing the dose, and an engagement member configured to mechanically cooperate with the piston rod and with the housing.

Abstract: A discharge apparatus for discharging a product having compressed gas support comprises a container (1) having a discharge opening (12) and a pressure element (2), which is mounted displaceably in the container (1). A counterpressure element (13) is provided on the container (1) and is used to advance the pressure element (2) into the container in order to absorb a developing counterpressure when pressure is applied onto the pressure element (2). A compressed gas device (5, 7, 8) dispenses compressed gas in the region of the discharge opening (12), and comprises a valve (6) and a valve actuating device (14) to control the compressed gas dispensing. The actuating device (14) is provided on the counterpressure element (13) to ensure that when discharging the product from the container, at the same time the compressed gas device can be actuated by applying pressure onto the pressure element, whereby compressed gas exits the discharge opening at the same time as the fluid product.

Abstract: A drive mechanism for a medication delivery device containing a resilient member and having a rotation member configured to be rotated in a first direction during setting of a dose of a medication and to be rotated in a second direction during delivery of the dose, where rotation member is coupled to a drive member that is coupled to a piston rod such that on dose delivery the piston rod is displaced in a distal direction to dispense a medicament and where the resilient member prevents movement of the drive member and the piston rod during dose setting.

Abstract: The present invention relates to a reservoir unit (40, 140, 240) for a drug delivery arrangement (1, 100, 200), the reservoir unit (40, 140, 240) comprising: a housing (41, 141, 241) adapted to accommodate a fluid substance and comprising a displaceable wall (43, 143, 243), a fluid transport member (50, 150, 250) comprising a fluid outlet (52, 152, 252), first fluid communication means (53, 153, 253) for providing fluid communication with an interior of another reservoir, and second fluid communication means (54, 154, 254) for providing fluid communication with an interior (44, 144, 244) of the housing (41, 141, 241), and coupling means (45, 145, 245) adapted for connection with mating coupling means associated with the other reservoir. The invention further relates to a drug delivery arrangement (1, 100, 200) employing the reservoir unit (40, 140, 240).

Abstract: An injection device, which can be, e.g., an insulin pen, can capture and transmit injection and/or medicament information to another device, such as, e.g., a blood glucose meter. The injection and medicament information can include, e.g., time and date of injection, type of medicament injected, and dosage amount. The injection device can include a dial cap that can be rotated to select a dosage amount to be injected. In some embodiments, the dial cap can include a microcontroller with transmitter, a Hall effect sensor, and a ring magnet. In some embodiments, the injection device can include a medicament cartridge with a 1-wire EEPROM, which can have medicament information stored therein. Methods of operating an injection device are also provided, as are other aspects.

Abstract: An injection device having a delivery element with an inner thread may be driven by rotation and includes a cylindrical outer wall region, which is substantially smooth. Such features provide a delivery element configured such that it is less intimidating to patients than known threaded rods, and may facilitate easy cleaning. The delivery element may be non-rotatably guided and axially spring-loaded, and may be inserted axially into the housing when the reservoir is replaced. The driving thread element for the delivery element may be mounted in the vicinity of the distal end of the housing.

Abstract: The present invention relates to a medical injection system comprising a medical injection device (100) of the type comprising a rotatable dose setting member (160). The system further comprises a dose limiter module (200) adapted for being releasably coupled to the injection device (100). The dose limiter module (200) comprises a dose limiter base (201) and a limiter (240) arranged relative to the dose limiter base (201) so that their relative position is adjustable to set an adjusted dose limiting position. When the dose limiter module (200) is coupled to the injection device (100), the limiter (240) cooperates with the dose setting member (160) to define a blocking means for preventing rotation of the dose setting member (160) beyond the adjusted dose limiting position.

Abstract: The present invention provides a sterile solution comprising octreotide acetate in a pharmaceutically acceptable vehicle, wherein solution is present as a reservoir in a multiple dose pen injection device, the device being adapted to subcutaneously inject a portion of the said reservoir in multiple daily doses and further being adapted to provide multiple portions of the said solution, while the reservoir remains sterile.

Abstract: The invention relates to a dose setting mechanism, which is operable to be coupled to a medication cartridge and which comprises means that prevent the user from setting a dose greater than the remaining medication in the cartridge. The dose setting mechanism comprises a shaft. A helical groove having a first pitch is provided along a first portion of the shaft. The dose setting mechanism further comprises a nut member disposed on the helical groove of said shaft. During dose setting, the shaft is rotated relative to the nut member while the nut member traverses along the groove from a distal end of the shaft towards a proximal end of the shaft.

Abstract: A syringe including a barrel having an internal reservoir for containing a volume of medication, a plunger received within the barrel and axially moveable relative thereto to change the volume of the medication in the reservoir, a first set of indicia marked on the barrel indicating volumetric dosage of the medication calibrated based on a predetermined patient characteristic, and a second set of indicia marked on the barrel having a correlation with the first set of indicia, the second set of indicia indicating volumetric dosage of the medication calibrated based on a medication unit of measurement. A kit including a syringe and a pre-filled medication container calibrated based on a patient characteristic.

Abstract: The present invention relates to a method and to a monitoring device for monitoring operation of a drug delivery device, the monitoring device comprising of at least a first and a second sensor arranged at a distance from each other with regard to a first direction and being adapted to generate a first and a second electrical signal in response to an operation of the device, a processing unit configured to determine a time delay between the first and the second electrical signals and being adapted to determine at least one state parameter of the drug delivery device on the basis of said time delay.

Abstract: A system comprises a drug reservoir and means for expelling drug from the reservoir, the drug expelling means comprising setting means allowing a user to set a drug dose to be expelled from the reservoir, and actuation means for driving or releasing the drug expelling means to expel the set dose amount. The system further comprises a first electronic data processing system adapted to capture and store data representing a property related to the amount of drug expelled from the reservoir by the expelling means, and a second electronic data processing system adapted to receive and store data from an external source, wherein the system is configured to not allow code or data processed by the second electronic data processing system to be processed by the first electronic data processing system.

Abstract: The present invention relates to a medical delivery comprising a) a housing (101) adapted to accommodate a drug in a drug reservoir (110), the housing (101) having an exterior surface defining at least one non-circular section, b) a drive mechanism for expelling doses of drug from the drug reservoir (110) and c) an operable control member (150) arranged at the non-circular section of the housing, the operable control member (150) being movable relative to the non-circular section of the housing for altering a parameter relating to the operation of the medical delivery device. The operable control member (150) comprises a belt-like structure arranged to move along the non-circular section of the housing so that respective portions of the operable control member change radius of curvature as the respective portions move relative to the non-circular section of the housing.

Abstract: A system for optimizing a patient's basal insulin dosage regimen over time, adapted to determine from blood glucose values whether and by how much to vary a patient's present recommended amount of the insulin-containing drug in order to maintain the patient's future blood glucose level measurements within a predefined range, and wherein a given blood glucose value is disregarded if no patient-actuated operation being indicative of the administration of a dose of an insulin containing drug has been detected in a pre-defined amount of time prior to the determination of the given blood glucose value.

Abstract: Drug injection device (400) comprising expelling means for expelling an amount of drug from a reservoir, the expelling means comprising setting means (411) allowing a user to set a dose to be expelled, and actuation means (413) for releasing the drug expelling means to expel the set dose. The actuation means comprises an actuation member adapted to be moved between an initial position, an intermediate position, and an actuated position in which the expelling means is actuated to expel the set dose. The device further comprises an electronically controlled capturing system (420) for capturing data representing the amount of drug expelled from the reservoir by the expelling means, and switch means for starting initialization of the capturing system when the actuation member is moved to its intermediate position.

Abstract: A dose measuring device for a drug delivery device is provided. The dose measuring device includes a main body and a dial sleeve coupled to the main body to spirally move, the dose measuring device including a housing provided to be removable from the main body, a rotation ring received in the housing to rotate, an encoder installed in the housing to detect the amount of rotation of the rotation ring, and an auxiliary sleeve provided to be removable from the dial sleeve and to spirally move together with the dial sleeve in the housing, in which the rotation ring is bound to the auxiliary sleeve to rotate together with the auxiliary sleeve and is fixed in the housing in a longitudinal direction of the main body.

Abstract: An injection device (1) for delivering a predetermined fixed dose of liquid drug, the device (1) comprising a housing (2), a first and second tubular members (7, 10). The first tubular member (7) and the housing are engaged via a first track (8) and a first protruding part (9), and the first and second tubular members (7, 10) are engaged via a second track (11) and a second protruding part (12). The first track (8) comprises a first portion (8a) which the first protruding part (9) travels during setting of the dose, and the second track (11) comprises a first portion (11a) which the second protruding part (12) travels during setting of the predetermined fixed dose. The first 10 portions (8a, 11a) of the first (8) and second (11) tracks are shaped in such a manner that the second tubular member (10) is prevented from rotating during setting 15 of a dose. The second tubular member (10) is rotationally locked to a piston rod (13), and rotation of the piston rod (13) during dose setting is thereby prevented.

Abstract: The present invention relates to an injection device comprising an optically-based sensor for determining the position or setting of a dose setting member arranged to set a dose to be injected from the injection device. In particular, the present invention relates to an injection device comprising a rotatably mounted member having a plurality of optically coded paths arranged on an outer surface thereof. The rotatably mounted member is operatively connected to the dose setting member and is adapted to rotate with the dose setting member.

Abstract: An injection delivery system for automatically injecting fluid into an injection site includes at least one support element and a carriage moveably mounted to the at least one support element so that the carriage can move linearly relative thereto. The carriage has a support structure for removably receiving and carrying a syringe assembly for movement with the carriage, and a carriage actuator is operable to cause such linear movement of the carriage. A plunger actuator is carried by the carriage so as to move with the carriage, and is adapted to be operably coupled to a syringe plunger for causing linear movement of the syringe plunger within a syringe barrel. The carriage actuator and plunger actuator include respective inputs for receiving movement instructions, and may be coupled to an electronic controller that provides such instructions.

Abstract: A medication injection pen (50) includes a housing (1) and a dose set knob (2) rotatably connected to the housing (1) for setting a dose. An indicator member (200) is movable between an visible position indicating a zero position of the dose set knob (2) and a non-visible position indicating a non-zero position of the dose set knob (2). The indicator member is visible to a user in the visible position and not visible in the non-visible position. The dose set knob is in the zero position when a set dose has been completely administered. Accordingly, a visible indication is provided to a user when a set dose has been completely administered.

Abstract: Some embodiments of a medical infusion pump system include a pump device having a flexible pushrod that can adjust from a curved configuration to a generally straight configuration. The flexible pushrod is part of a drive system of the pump device so that the flexible pushrod can be controllably and incrementally advanced toward a medicine reservoir to incrementally dispense the medicine therein. In particular embodiments, the flexible pushrod may comprise an anti-rotation mechanism, an anti-torsion mechanism, or a combination thereof.

Abstract: Some embodiments of a medical infusion pump system include a pump device having a flexible pushrod that can adjust from a curved configuration to a generally straight configuration. The flexible pushrod is part of a drive system of the pump device so that the flexible pushrod can be controllably and incrementally advanced toward a medicine reservoir to incrementally dispense the medicine therein. In particular embodiments, the flexible pushrod may comprise an anti-rotation mechanism, an anti-torsion mechanism, or a combination thereof.

Abstract: An assembly for a drug delivery device comprises a housing having a proximal end and a distal end, a dose button configured to be moved with respect to the housing for setting and delivering a dose of a drug, and a resilient setting member. For a dose delivery movement, the dose button is arranged to be moveable in the distal direction with respect to the housing from a dose delivery position, thereby deforming the resilient setting member to store energy in the resilient setting member. The assembly is configured to use the energy stored in the resilient setting member for a dose setting movement to move the dose button in the proximal direction with respect to the housing into the dose delivery position. Furthermore, a drug delivery device is provided.

Abstract: A lock for a dosing mechanism of an injection device, the lock including at least one holding element that interacts with the dosing mechanism, or with a dosing element of the dosing mechanism, whereby an adjustment movement of the dosing mechanism or the dosing element is prevented in a starting position of the lock and is possible only after a movement or displacement of the lock or the holding element. An injection device used in conjunction with a two-chamber ampoule is encompassed, as is a method for preparing the injection device for dispensing a substance wherein the ampoule is introduced into the injection device and a lock is released when the ampoule has been introduced far enough to appropriately mix the substances in the two chambers, whereupon the mixed substances can be dispensed from the ampoule.

Abstract: A drug delivery device is presented comprising of a housing, a plurality of contacts, and a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with a plurality of tracks together forming an encoder, each track comprising conductive segments and non-conductive segments, and wherein the cylindrical member is supported in the housing such that each track is engaged by a respective one of the plurality of contacts.

Abstract: A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove. The inner housing guides a driver having either a blocking or locking member disposed inside the driver that can lock a flexible tab to an internal groove during dose delivery in the inner housing such that the driver follows the path of the groove and to advance a spindle to move a cartridge bung. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing.

Abstract: A dosing device for setting a dose to be delivered by an injection device, the dosing device including a setting element, e.g. a setting sleeve, and a drawing element, e.g. a rotating sleeve, which can be rotated out of the dosing device for preparing a dose delivery. A stop is on the setting element, and a counter stop is on the drawing element so that a rotational motion of the drawing element relative the setting element can be limited by the stops. The present invention encompasses a method for setting a dose that should be delivered by an injection device, wherein the dose to be delivered can be set by a setting element, e.g. a setting sleeve, and a drawing element of the injection device, e.g. a rotating sleeve, can subsequently draw up the dose by effecting a rotational motion to deliver the set dose from the injection device in a subsequent step. According to the present invention, the setting process is isolated from drawing process.

Abstract: The present invention relates to a medicament container holder arrangement comprising a medicament container holder 16 and a medicament container 18 wherein the medicament container holder 16 is provided with distally arranged support surfaces 25 for flanges 24 arranged on a distal part of the medicament container 18 to be placed in said medicament container holder 16, which medicament container 18 is arranged with a needle shield 20 to the proximal end thereof, wherein said needle shield 20 has a diameter generally equal or larger than the diameter of said medicament container 18, wherein said medicament container holder arrangement further comprises holders arranged on the container holder for holding said medicament container 18 around a proximal shoulder portion 22 thereof and a resilient support element 23 arranged between the flanges 24 and the support surfaces 25 whereby the holders and the resilient support element 23 absorb and spread forces between the medicament container and the container holder.

Abstract: A medicament delivery device for the administration of one or more drug agents is described. The device has a priming mode and a drug delivery mode for administering delivery of the drug agents. The device includes a controller operative for controlling the device to perform a priming operation, and a user interface for activation of the priming operation. The controller is operative to perform the priming operation by way of a plurality of intermittent doses of medicament, the number of intermittent doses being dependent on the activation of the user interface.

Abstract: A medicated module for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module containing a single dose of a secondary medicament and where both medicaments are delivered through a hollow needle. The medicated module is initially in a locked state until attached to a drug delivery where interaction of the cartridge holder with the module bypass housing changes the module to a triggerable state. The medicated module does not require the user to manually engage a reservoir containing the secondary medicament. Instead, a biasing member automatically activates the reservoir when the needle guard is retracted when the module is in the triggerable state. The needle guard prevents accidental needle sticks before and after an injection, and locks after removal from the injection site.

Abstract: The present invention relates to an injection device comprising a torsion spring operatively connected to a dose setting member being adapted to set a dose to be ejected from the injection device. A rotatably mounted display member adapted to display the dose to be ejected in accordance with a setting of the dose setting member is also provided. The rotatably mounted display member is adapted to be rotated over an angle corresponding to at least one revolution of the display member. The display member may be implemented as a dose indicator barrel having numerals arranged along a helical path on an outer surface thereof, or alternatively, as a counting device having two or more display wheels having numerals arranged on an outer surface thereof.

Abstract: An injection device with a housing and an operating element or coupling element mounted in the housing in such a way that the operating element or coupling element may be retained in a first position by a first holding connection and may be displaced into a second position that is axially offset relative to the first position after introducing an ampoule. In some embodiments, the operating element or coupling element may be retained by a second holding connection in the second position.

Abstract: A housing for a dispensing apparatus. The housing comprising a main housing and a dose dial sleeve. The dose dial sleeve comprising a helical groove configured to engage a threading provided by the housing. A dose knob is disposed near a proximal end of the dose dial sleeve and a piston rod is provided within the housing. The piston rod is non-rotatable during a dose setting step. A driver comprises an internal threading near a distal portion of the driver and is adapted to engage an external thread of the piston rod. A tubular clutch is located adjacent a distal end of the dose knob and operatively coupled to the dose knob. The dose dial sleeve may extend circumferentially around at least a portion of the tubular clutch.

Abstract: A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove. The inner housing guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.

Abstract: A medication injector apparatus such as an injection pen. The injection pen may include a doseable quantity identifier that uses a rotational matrix and a sensor for electrically sensing the arrangement of the dose setting mechanism of the the pen, which identifier may be part of a therapeutic dose indicating system that utilizes a cartridge recognizer to recognize a concentration of medication so as to allow an automatic determination of a therapeutic dose.

Abstract: The present invention inter alia relates to a valve arrangement comprising at least two ports, a valve body and a valve piston, wherein the valve piston is at least partially movably arranged in the valve body, wherein the valve arrangement is configured to disable a fluid flow between the at least two ports in a first position of the valve piston in the valve body and to enable the fluid flow in a second position of the valve piston in the valve body, and wherein at least one port of the valve arrangement is arranged in the valve piston and at least one port of the valve arrangement is arranged in the valve body.

Abstract: An apparatus includes a syringe housing and a plunger slidably received within the syringe housing. A plunger magnet is secured to the plunger. A potentiometer housing is fixed to the syringe housing and includes a potentiometer disposed therein. A wiper magnet is also disposed within the potentiometer housing. Movement of the plunger magnet causes a corresponding movement of the wiper magnet.

Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.

Abstract: An assembly for a drug delivery device is provided comprising a housing, a cartridge holder releasably connectable to the housing, a resilient member, and an interaction member which is configured to mechanically cooperate with the resilient member and with the cartridge holder. The resilient member is configured to rotationally bias the interaction member. The assembly has a locked state where the cartridge holder is connected to the housing, the cartridge holder being obstructed from movement with respect to the housing, and an unlocked state where the connection between the cartridge holder and the housing is released, the cartridge holder being freely moveable with respect to the housing.

Abstract: A drug delivery device is provided which comprises a housing, a dispensing end for dispensing a drug from the drug delivery device, a flexible container for holding the drug, the flexible container comprising an outlet, the outlet being connected to the dispensing end, and a squeezing member for squeezing the flexible container, wherein, for dispensing a dose of the drug from the drug delivery device, the squeezing member and the flexible container are axially displaceable relative to one another, the squeezing member rotating with respect to the housing during the relative axial displacement and squeezing the flexible container, thereby urging the dose of the drug from the container through the outlet. Furthermore, using a rotatable roll in a drug delivery device is described.

Abstract: The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device.

Abstract: An injection device for injection of set doses of medicine from a cartridge has a nut that is screwed up along a threaded piston rod during a dose setting operation. The nut is screwed along the piston rod by rotating a dose setting member. A rotational coupling mechanism includes an axially displaceable coupling member which is rotated as a function of axial displacement. During dose setting, the nut is allowed to rotate relative to the coupling member. During injection, the coupling member is rotationally locked to the nut. This provides a dose setting and injection mechanism wherein the nut member is both rotated during dose setting and during injection.

Abstract: An applicator, for example an injector (100), includes a flow control means including a first member (2) and a second member (6) for controlling flow from an inlet (4) to an outlet (5). A hinged linkage (17) is provided having a first end (18) rotatably engaged with the first member and a second end (19) rotatably engaged with the second member. The linkage (17) is moveable between a collapsed position and an over-center locked position which prevents relative movement of the first member (2) towards the second member (6). Linkage unlocking means (28) are provided which move the hinge (22) away from the over-center locked position so that the first and second members can be moved together. A similar linkage (10) prevents unwanted movement of a needle shroud (8). A needle shroud (8) which can be used to remove the needle (7) from the injector (100) is also described.

Abstract: An auto-injection device has a housing with a medicament container disposed within; a dose setting mechanism for setting a dose of a medicament; a drive nut and a plunger rod operably connected, with an energy accumulator operably connected to the dose setting mechanism; and an activating mechanism and a positioning mechanism operably connected to the plunger rod for locking the plunger rod from being displaced. The positioning mechanism includes a locking nut arranged to cooperate with fixed, flexible locking features for locking the locking nut from rotation. A resilient member arranged inside the plunger rod is configured to allow the plunger rod to be resiliently and axially displaced when the locking nut is unlocked.

Abstract: A dose setting mechanism for a drug delivery device is provided comprising a dose setting member, a drive member, a clutch, a first clicker and second clicker. The first clutch and a second clutch are designed and adapted to each other such that at any time during operation either the first clutch rotationally couples the dose setting member and the drive member and/or the second clutch rotationally couples the drive member and the first clicker component. Further, the invention refers to an injection device with such a dose setting mechanism.

Abstract: The invention relates to a dosing mechanism for a fluid, comprising an inlet, an outlet, a dosing pipe and two valve groups with an inlet valve and an outlet valve each, wherein the inlet is connected to both inlet valves and the outlet is connected to both outlet valves, wherein the inlet valve of one group is arranged to connect the inlet to a first end of the dosing pipe while the outlet valve of the same group is arranged to connect the outlet to a second end of the dosing pipe, wherein the inlet valve of the other group is arranged to connect the inlet to the second end of the dosing pipe while the outlet valve of the same group is arranged to connect the outlet to the first end of the dosing pipe, wherein control means are arranged to open only the valves of one group at a time thereby allowing the fluid to flow from the inlet through the dosing pipe to the outlet, wherein a dosing object is arranged in the dosing pipe in a manner to be translated from one end towards the other by the fluid, wherein a d

Abstract: A resettable drug delivery device is provided comprising a body, a cartridge holder for receiving a cartridge, and means for releasably coupling the cartridge holder to the body or the dose setting mechanism. During an initial rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a first axial direction relative to the body or the dose setting mechanism and during a continued rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a second, contrary axial direction.

Abstract: Systems and methods for infusion of fluids using stored potential energy and a variable flow resistor. In one aspect of the present disclosure, there is provided an infusion device that includes a plunger situated within a vessel so as to define a chamber within which a volume of fluid can be accommodated between a downstream surface of the plunger and the vessel. The infusion device further includes an outflow path through which the fluid in the chamber can be dispensed upon displacement of the plunger by a force acting thereon. A variable flow resistor is situated within the outflow path and is configured to allow a substantially constant fluid flow rate from the vessel to be maintained as the force acting on the plunger decreases.

Abstract: A dispensing device for dispensing first and second medicaments to a patient that is made up of first and second stand-alone, interconnectable assemblies. The first of these assemblies comprises a fluid reservoir assembly that houses a fluid reservoir defining component while the second assembly comprises a fluid delivery and control assembly that includes an adding assembly for controllably dispensing the second medicament to the patient, a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the first assembly toward the patient via a plurality of fluid flow control passageways.