Abstract: The disclosure provides a heart rate monitor (HRM) circuit. The HRM circuit includes an analog front end (AFE). The AFE receives a Photoplethysmographic (PPG) signal, and generates a fine PPG signal. A motion cancellation circuit is coupled to the AFE, and receives the fine PPG signal and an accelerometer signal. The motion cancellation circuit subtracts the accelerometer signal from the fine PPG signal to generate a coarse heart rate. A peak detector is coupled to the motion cancellation circuit and the AFE, and generates an instantaneous heart rate. A filter is coupled to the peak detector, and generates an estimated heart rate from the instantaneous heart rate, the estimated heart rate is provided as a feedback to the peak detector.

Abstract: Systems, apparatus, methods and computer-readable storage media that mitigate implantable medical device (IMD) power drain associated with stalled telemetry sessions are provided. In one embodiment, an IMD includes a housing configured to be implanted within a patient, a memory and a processor that executes executable components stored in the memory. The executable components include a communication component configured to receive a communication request from an external device via a telemetry communication link established between the IMD and the external device. The communication request can comprise a request for data. The executable components can also comprise a throughput monitoring component configured to monitor uplink throughput associated with transmission of the data by the IMD to the external device via the telemetry communication link based on reception of the communication request.

Abstract: A plurality of wireless vital sensors for capturing biometric data of individuals is laid out and fixed at predetermined setting locations. The vital sensors are configured to sense the biometric data of an individual via non-contact when the individual enters the sensing area of any one of the plurality of vital sensors. Moreover, there is no discomfort while the wireless vital sensor is attached or no risk of damage to or destruction of the wireless vital sensor due to collisions during games. Additionally, the measuring device also includes the identification sensors for identifying a mobile object, and the individual corresponding to the biometric data sensed by the vital sensors is identified by the RFID data from the identification sensor. Accordingly, in a configuration where the wireless vital sensors can capture the biometric data of an unspecified number of individuals, which individual the biometric data belongs to can be surely identified.

Abstract: According to the present invention, a method and apparatus for non-invasively determining the blood oxygen saturation level within a subject's tissue is provided. The method comprises the steps of: a) providing a spectrophotometric sensor operable to transmit light into the subject's tissue, and to sense the light; b) detecting light after passage through the subject's tissue using the sensor, and producing initial signal data from the light sensed; c) calibrating the sensor to that particular subject using the initial signal data, thereby accounting for the specific physical characteristics of the particular subject's tissue being sensed; and d) using the calibrated sensor to determine the blood oxygen parameter value within the subject's tissue.

Abstract: A non-invasive method of detecting anomalous tissue, such as cancerous or injured tissue, in a patient. At least two hemoglobin signal components of hemoglobin levels in at least one segment of tissue of the patient are non-invasively measured over time. Time varying changes of at least a first of the hemoglobin signal components are measured with respect to at least time varying changes of a second of the hemoglobin signal components. A co-varying coordinate system of the time varying changes is generated. Any anomalous tissue in the measured segment of tissue is detected from a signature of the measured segment of tissue in the co-varying coordinate system which differs from a signature of non-anomalous tissue in the co-varying coordinate system. Preferably, five hemoglobin signal components are measured: oxyHb, deoxyHb, total Hb (totalHb=oxyHb+deoxy Hb), Hb oxygen saturation (HbO2Sat=(oxyHb/totalHb)*100), and tissue-hemoglobin oxygen exchange HbO2Exc (deoxyHb?oxyHb).

Abstract: A plethysmographic respiration processor is responsive to respiratory effects appearing on a blood volume waveform and the corresponding detected intensity waveform measured with an optical sensor at a blood perfused peripheral tissue site so as to provide a measurement of respiration rate. A preprocessor identifies a windowed pleth corresponding to a physiologically acceptable series of plethysmograph waveform pulses. Multiple processors derive different parameters responsive to particular respiratory effects on the windowed pleth. Decision logic determines a respiration rate based upon at least a portion of these parameters.

Abstract: Methods and systems are provided for determining physiological information based on distortion factors and physiological signals. Physiological signals are received by a system. The system may receive or determine a value indicative of oxygen saturation. The distortion factors may be calculated based on the value indicative of oxygen saturation and the physiological signals. The distortion factors may be used to determine physiological information.

Abstract: Embodiments of the present disclosure relate to a system and method for determining a risk, onset, or presence of hypovolemia based on one or more features of a plethysmographic waveform during a patient breathing cycle. For example, a hypovolemic patient may exhibit characteristic changes in pulse amplitude or stroke volume during inhalation and exhalation relative to a healthy patient. Further, a trend or pattern of such features may be used to assess the patient's fluid condition.

Abstract: A measuring device that can obtain a stable measurement result is realized. The measuring device includes a measuring portion (14) that is arranged in one of a placing portion (12) where a fingertip portion (A) is placed, and an interposing portion (11) facing the placing portion (12), and interposing, together with the placing portion, the fingertip portion (A), emits excitation light and receives fluorescence, and a fixing force supply portion (13) that supplies, to the fingertip portion (A) through the interposing portion (11), force which is capable of fixing a relative positional relationship between the fingertip portion (A) and the measuring portion (14).

Abstract: Mutation signal processing methods, devices and medical detecting apparatuses are described. The method includes detecting whether or not a mutation signal exists in an input signal; if the mutation signal exists in the input signal, processing the input signal by a filter to obtain an output signal, and updating a prestored difference value according to a difference value obtained by subtracting the output signal from the input signal; and if the mutation signal does not exist in the input signal, using a difference value obtained by subtracting the prestored difference value from the input signal as the output signal.

Abstract: A biological information monitoring apparatus includes: a measurer which is configured to measure biological information of a subject; a display on which a measurement value of the biological information measured by the measurer is displayed; a calibration controller which, when a predetermined condition is satisfied, is configured to perform a calibration process on the measurer; a time measurer which is configured to acquire a remaining time before the calibration process is ended; and a display controller which is configured to cause an index indicating the remaining time to be displayed on the display.

Abstract: An optical perfusion sensor may monitor blood oxygen saturation of blood-perfused tissue, which may be referred to as tissue perfusion, until a tissue perfusion value is within a threshold range of a reference value, and, in some examples, for at least a minimum period of time. The tissue perfusion value may indicate an absolute blood oxygen saturation level or a relative change in blood oxygen saturation level. The reference value may be, for example, determined by an oxygen (O2) variation index that indicates a change in blood oxygen saturation of tissue. In some examples, the optical perfusion sensor may be activated upon detecting a cardiac event, such as a cardiac arrhythmia. In addition, in some examples, cardiac signal monitoring may be activated upon detecting a threshold change in tissue perfusion.

Abstract: An electrical circuit includes a sensor configured to generate a current signal comprising a first portion comprising a contribution from a target source and/or a second portion comprising a contribution from sources other than the target source, a trans-impedance amplifier that amplifies the current signal and generate a low noise signal, and a high pass filter that converts the low noise signal into an AC signal having a positive amplitude, a negative amplitude, and a zero cross-over point between the positive and negative amplitudes. The circuit also includes a positive integrating amplifier that receives the positive amplitude of the AC signal and generates a positive integrated value over an integration period, and a negative integrating amplifier that receives the negative amplitude of the AC signal and generates a negative integrated value over the integration period. The circuit further includes at least one analog-to-digital converter that receives the integrated values.

Abstract: A catheter system and related method for measuring the oxidation state of biological molecules in a region of a measurement site of a subject. The system may include a catheter device having one or more emitters in mechanical communication with the catheter and configured to make contact with a tissue wall of the subject. The catheter device also includes one or more detectors in mechanical communication with the catheter and configured to make contact with the tissue wall of the subject. The emitters and the detector are in electromagnetic radiation communication with one another, whereby the electromagnetic radiation communication allows visible radiation or near infrared radiation emitted by emitters to be detected by the detector to determine tissue oxidation state of the region of the measurement site of the subject.

Abstract: Systems and methods for implementing power management features while providing a wireless asymmetric network are disclosed herein. In one embodiment, a system includes a hub having a wireless control device that is configured to control communications and power consumption in the wireless asymmetric network architecture and sensor nodes each having at least one sensor and a wireless device with a transmitter and a receiver to enable bi-directional communications with the wireless control device of the hub. The wireless control device is configured to determine a scheduled timing of operating each sensor node during a first time period that is close in time with respect to a transmit window of the transmitter and during a second time period that is close in time with respect to a receive window of the receiver for each wireless device to reduce power consumption of the wireless devices of the sensor nodes.

Abstract: Embodiments of the present invention relate to a method for analyzing pulse data. In one embodiment, the method comprises receiving a signal containing data representing a plurality of pulses, the signal generated in response to detecting light scattered from blood perfused tissue. Further, one embodiment includes performing a pulse identification or qualification algorithm on at least a portion of the data, the pulse identification or qualification algorithm comprising at least one constant, and modifying the at least one constant based on results obtained from performing the pulse identification or qualification algorithm, wherein the results indicate that a designated number of rejected pulses has been reached.

Abstract: A biological information measurement device according to the present invention detects a signal expressing biological information from a fingertip using an internal sensor (S1). A first perfusion index and first biological information aside from the first perfusion index are obtained from the signal detected by the internal sensor (S2, S3). It is determined whether or not the first perfusion index is greater than or equal to a first threshold (S4). When the first perfusion index is greater than or equal to the first threshold, the first biological information is permitted to be displayed in a display unit (S5). However, when the first perfusion index is less than the first threshold, a notification is made indicating that an external sensor that is lighter than a main body, is an entity separate from the main body, and is communicably connected to the main body is to be used (S6).

Abstract: A cancer screening method includes changing a compression state of selected tissue; and obtaining a signal indicative of a response of an optical property of the selected tissue in response to the change in the compression state.

Abstract: A regional oximetry system has a display and at least one processor causing a plurality of views to be displayed on the display, each configured to occupy at least a portion of the display. The views are adapted to present data responsive to at least one physiological signal. A first sensor port is configured to receive at least a first physiological signal representative of a regional tissue oxygenation level, and a second sensor port is configured to receive at least a second physiological signal representative of an arterial oxygen saturation level. One view presents a first trend graph of the first physiological signal and a second trend graph of the second physiological signal. An area between the first trend graph and the second trend graph can include a differential analysis of regional-to-central oxygen saturation.

Abstract: Described herein are methods, apparatuses, and systems for heart monitoring of a patient. The heart monitoring system can be used to take an electrocardiogram (ECG) using only two electrodes. A handheld device can be used to sequentially measure the electrical signal between different positions on a patient's body. The electrical signals can be processed and analyzed to prepare an ECG for the patient, including a 12-lead ECG.

Abstract: Obtaining physical model data for CAD model generation with a process that includes: receiving a first acceleration-based path data set including acceleration data for an accelerometer device as it was traced over a first path along the surface of a physical object, converting the first acceleration-based path data set to a first position-based data set including position data for the accelerometer as it was traced over the first path along the surface of the physical object, and generating a three dimensional object model data set based, at least in part on the position data of the first position-based data set.

Abstract: The present disclosure uses physiological data, ECG signals as an example, to evaluate cardiac structure and function in mammals. Two approaches are presented, e.g., a model-based analysis and a space-time analysis. The first method uses a modified Matching Pursuit (MMP) algorithm to find a noiseless model of the ECG data that is sparse and does not assume periodicity of the signal. After the model is derived, various metrics and subspaces are extracted to image and characterize cardiovascular tissues using complex-sub-harmonic-frequencies (CSF) quasi-periodic and other mathematical methods. In the second method, space-time domain is divided into a number of regions, the density of the ECG signal is computed in each region and inputted into a learning algorithm to image and characterize the tissues.

Abstract: Methods and systems for evaluating the electrical activity of the heart to identify novel ECG patterns closely linked to the subsequent development of serious heart rhythm disturbances and fatal cardiac events. Two approaches are describe, for example a model-based analysis and space-time analysis, which are used to study the dynamical and geometrical properties of the ECG data. In the first a model is derived using a modified Matching Pursuit (MMP) algorithm. Various metrics and subspaces are extracted to characterize the risk for serious heart rhythm disturbances, sudden cardiac death, other modes of death, and all-cause mortality linked to different electrical abnormalities of the heart. In the second method, space-time domain is divided into a number of regions (e.g., 12 regions), the density of the ECG signal is computed in each region and input to a learning algorithm to associate them with these events.

Abstract: A biological information measurement device includes a device main body which includes a sensor, a processor, and a battery. The sensor acquires biological information of a user. The processor instructs the sensor to acquire the information at certain discrete times with a period, and processes the information. The battery supplies power to the sensor and the processor. The period is selected based on the biological information.

Abstract: Various implementations described herein are directed to a method for mitigating radar interference. The method may include receiving time domain signals from a radar device and transforming the time domain signals to time-frequency domain signals. The method may include comparing each time-frequency domain signal with one or more surrounding time-frequency domain signals to determine which of the time-frequency domain signals have interference. The method may include repairing the time-frequency domain signals having interference.

Abstract: A pulse wave measuring device includes a light emitter unit, a light receiver unit, a pulse wave measuring unit and a contact portion. The light receiver unit receives reflected light, which is reflected from a finger after transmission of the light from the light emitter unit. The pulse wave measuring unit measures a pulse wave based on the reflected light, which is received with the light receiver unit. The finger contacts the contact portion at a time of measuring the pulse wave. The contact portion has a recess, which receives at least a portion of the finger at the time of measuring the pulse wave, and a protrusion is provided in an inside of the recess.

Abstract: Systems and methods are provided for determining respiration information from physiological signals such as PPG signals. A physiological signal is processed to generate at least one respiration information signal and an autocorrelation sequence is generated based on the at least one respiration information signal. In some embodiments, a respiration peak is identified based on the autocorrelation sequence and a composite peak is generated based on the identified peak and at least one previous respiration peak. Respiration information is calculated based on the composite peak. In some embodiments, a determination is made whether the autocorrelation sequence includes an undesired harmonic. When the autocorrelation sequence includes an undesired harmonic, the autocorrelation sequence may not be used in the calculation of respiration information.

Abstract: An apparatus for analyzing a biosignal is provided. The apparatus includes a communicator configured to receive from an external device a first biosignal of an object detected by the external device; a synchronizer configured to transmit a synchronization signal to from the external device or receive the synchronization signal from the external device; at least one biosignal detector configured to detect a second biosignal of the object according to the synchronization signal; and a processor configured to compare characteristics of the first biosignal and the second biosignal and obtain biometric information having correlation with a result of the comparison.

Abstract: Provided is a biometric device including a light source unit arranged facing a first part on a surface of an organism and configured to irradiate the first part with excitation light, and a light-reception unit arranged facing a second part adjacent to the first part on the surface of the organism and configured to receive fluorescence light which is generated by the excitation light exciting a first body substance of the organism and emitted from the second part.

Abstract: A physiological monitoring system may receive a sensor signal from a physiological sensor. The system may determine a first and second change metric based on the sensor signal, and may determine a venous signal based on the change metrics. In some embodiments, the sensor signal may be a photoplethysmograph signal that includes both arterial and venous information. By subtracting a second change metric from a first change metric, arterial contributions may be substantially removed, resulting in a signal primarily comprising venous information. The venous signal may be indicative of changes in the venous blood, and may be used to determine a physiological parameter, for example, blood pressure. The venous signal may also be used to trigger an event, for example, calibration of a blood pressure measurement.

Abstract: Methods, devices and systems for obtaining heart rate by obtaining apical and non-apical heart rate datum using first and second heart rate monitoring devices. The apical and non-apical heart rate data are input into a heart rate verification module (HRVM) that includes a number of programming instructions for effecting the invention. An apical heart rate measure and non-apical heart rate measure are calculated in the HRVM, and an acceptable heart rate range is generated using the apical heart rate measure. Whether the non-apical heart rate measure is a reliable measure of a true heart rate is identified by determining whether the non-apical heart rate measure falls within or outside the acceptable heart rate range. A split display screen of the HRVM displays the apical heart rate measure, non-apical heart rate measure, and information identifying whether the non-apical heart rate measure falls within or outside the acceptable heart rate range.

Abstract: Apparatus configured to detect congenital heart disease (CHD) in newborns may comprise a body with a cavity configured to receive a hand or foot of a newborn. Sensor pairs of the apparatus may be configured scan such that the best signals can be selected, which can accommodate for movements of the newborn and/or facilitate impartialness as to which body part is inserted in the apparatus. Positions of the sensor pairs may be adjusted to ensure contact with the newborn's skin. A disposable cover may protect the newborn's skin from contacting the apparatus. The apparatus may include a pressure device so that CHD threshold values can be adjusted for different altitudes. The apparatus may integrate with electronic medical record (EMR) systems.

Abstract: Methods and systems are presented for determining whether a regional oximetry sensor is properly positioned on a subject. First and second metric values may be determined based on respective first and second light signals. The first and second metric values and a relationship between the first and second metrics are used to determine whether the sensor is properly positioned on the subject. The first and second metrics may form a pair of metrics, and whether the sensor is properly positioned on the subject may be determined based on whether the pair of metrics falls within a sensor-on region. In some embodiments, a plurality of metrics may be determined based on a plurality of received physiological signals. The plurality of metrics may be combined, using, for example, a neural network, to determine whether the regional oximetry sensor is properly positioned on a subject.

Abstract: The present invention provides for three-dimensional reflectance diffuse optical imaging of deep tissue blood flow distribution that removes the need for probe-tissue contact, thereby allowing for such technology to be applied to sensitive, vulnerable, damaged, or reconstructive tissue. The systems utilize noncontact application and detection of near-infrared light through optical lens and detection through a linear array or two-dimensional array of avalanche photodiodes or a two-dimensional array of detectors provided by charge-coupled-device (CCD). Both further feature a finite-element-method (FEM) based facilitation to provide for three-dimensional flow image reconstruction in deep tissues with arbitrary geometries.

Abstract: A method and system is provided for noise cleaning of photoplethysmogram signals. The method and system is disclosed for noise cleaning of photoplethysmogram signals for estimating blood pressure of a user; wherein photoplethysmogram signals are extracting from the user; the extracted photoplethysmogram signals are up sampled; the up sampled photoplethysmogram signals are filtered; uneven baseline drift of each cycle is removed from the up sampled and filtered photoplethysmogram signals; outlier cycles of the photoplethysmogram signals are removed and remaining cycles of the photoplethysmogram signals are modeled; and time domain features are extracted from originally extracted and modeled photoplethysmogram signals for estimating blood pressure of the user.

Abstract: Support structures for positioning sensors on a physiologic tunnel for measuring physical, chemical and biological parameters of the body and to produce an action according to the measured value of the parameters. The support structure includes a sensor fitted on the support structures using a special geometry for acquiring continuous and undisturbed data on the physiology of the body. Signals are transmitted to a remote station by wireless transmission such as by electromagnetic waves, radio waves, infrared, sound and the like or by being reported locally by audio or visual transmission. The physical and chemical parameters include brain function, metabolic function, hydrodynamic function, hydration status, levels of chemical compounds in the blood, and the like. The support structure includes patches, clips, eyeglasses, head mounted gear and the like, containing passive or active sensors positioned at the end of the tunnel with sensing systems positioned on and accessing a physiologic tunnel.

Abstract: Embodiments of the present invention include systems and methods that relate to pulse oximetry. Specifically, one embodiment includes an oximeter sensor comprising a light emitting element configured to emit light, a light detector configured to detect the light, and a memory chip having a built-in trimmed resistor, the trimmed resistor having a resistance value that is detectable by a monitor.

Abstract: A regional oximetry pod drives optical emitters on regional oximetry sensors and receives the corresponding detector signals in response. The sensor pod has a dual sensor connector configured to physically attach and electrically connect one or two regional oximetry sensors. The pod housing has a first housing end and a second housing end. The dual sensor connector is disposed proximate the first housing end. The housing at least partially encloses the dual sensor connector. A monitor connector is disposed proximate a second housing end. An analog board is disposed within the pod housing and is in communications with the dual sensor connector. A digital board is disposed within the pod housing in communications with the monitor connector.

Abstract: Described herein are methods, apparatuses, and systems for heart monitoring of a patient. The heart monitoring system can be used to take an electrocardiogram (ECG) using only two electrodes. A handheld device can be used to sequentially measure the electrical signal between different positions on a patient's body. The electrical signals can be processed and analyzed to prepare an ECG for the patient, including a 12-lead ECG.

Abstract: A biomedical signal sensing circuit including a first and a second modulation unit, an amplifying unit, a first and a second demodulation unit is provided. The first modulation unit performs a first modulation operation to a first biomedical signal according to a first signal to generate a first modulation signal. The second modulation unit performs a second modulation operation to a second biomedical signal according to a second signal to generate a second modulation signal. The amplifying unit amplifies the first and second modulation signals, and adds the amplified first and second modulation signals to generate a third modulation signal. The first demodulation unit performs a first demodulation operation to the third modulation signal according to the first signal to generate a first sensing signal. The second demodulation unit performs a second demodulation operation to the third modulation signal according to the second signal to generate a second sensing signal.

Abstract: The present disclosure provides a sensor with color-coded indications that various patient physiological parameters are being monitored, such as blood oxygen saturation, blood pressure, respiration rate, and respiration effort. The sensor may sense a physical characteristic used to monitor the physiological parameter, and a visible light emitter emits visible light of a first color that is color-coded to the physiological parameter, but is not used to sense the physical characteristic. The visible light emitter may emit visibly flashing light in response to the sensor sensing a threshold value of the physical characteristic. The sensor may include a second light emitter that may sense the physical characteristic, and may emit light of a second color that is color-coded to a first or second physiological parameter. In some embodiments, the first and second colors may visibly mix. The first and second visible light emitters may emit light independently, including visibly flashing light.

Abstract: A monitoring device with a pedometer function preferably comprises an article, an optical sensor, an accelerometer and processor. The optical sensor preferably comprises a photodetector and a plurality of light emitting diodes. A sensor signal from the optical sensor is processed with a filtered accelerometer output signal from the accelerometer to generate a pedometer function.

Abstract: An array of emitters includes a device substrate having first and second sides, a thermally and electrically conductive layer disposed on the first side of the device substrate, and an interconnect layer disposed on a first plurality of portions of the second side of the device substrate. The array of the emitters further includes a plurality of emitters disposed in a second plurality of portions of the device substrate, where the plurality of emitters is electrically coupled to the thermally and electrically conductive layer. Also, the array of the emitters includes a plurality of wirebond contacts configured to electrically couple a portion of the interconnect layer to a corresponding emitter of the plurality of emitters, and a plurality of encapsulations, where one or more encapsulations of the plurality of encapsulations are disposed on at least a portion of a corresponding wirebond contact of the plurality of wirebond contacts.

Abstract: A system, method, and device for monitoring a cardiac signal of a user includes an emitter (LED) for transmitting light toward skin of the user, a receiver (photodiode) for receiving a reflection of the transmitted light and generating a light intensity signal, and a processor configured to generate a photoplethysmogram (PPG) signal based on the light intensity signal. The PPG signal includes a cardiac component, a motion component and a respiratory component. An inertial sensor provides a motion signal to the processor based on sensed movement of the device and one or more time-variant filters are configured by the processor to filter the PPG signal to isolate the cardiac component of the PPG signal based on determined filter coefficients.

Abstract: An activity monitoring device and associated methods for using and interfacing with the activity monitoring device are provided. In one example, the activity monitoring device includes a housing configured for attachment to a body part of a user. Also included ins a display screen attached to the housing and a sensor for capturing physiological conditions of the user. The sensor is disposed along a surface of the housing so that the sensor is proximate to the body part, the body part having at least some exposed skin. The activity monitoring device also includes memory for storing the captured physiological conditions, and a processor for examining the captured physiological conditions. At a particular time, the processor automatically selects an application to execute from a plurality of applications based on characteristics of the captured physiological conditions.

Abstract: Systems and sensor clip assemblies for optically monitoring blood flowing through a blood chamber are provided. A sensor clip assembly includes emitters and photodetectors positioned on opposing arms, a signal conditioning circuit for conditioning raw analog signals generated by the photodetectors while the sensor clip assembly is fastened to a blood chamber, and an analog-to-digital converter for converting the conditioned analog signals to raw digital data. The sensor clip assembly may output the raw digital data to an external device and receive synchronized control signals from the external device, or the sensor clip assembly may include a microcontroller for performing calculations on the raw digital data and providing synchronized control signals internally. Parameters of blood flowing through the blood chamber such as hematocrit, oxygen saturation, and change in blood volume may be calculated from the raw digital data derived from the raw analog signals generated by the photodetectors.

Abstract: Obtaining physical model data for CAD model generation with a process that includes: receiving a first acceleration-based path data set including acceleration data for an accelerometer device as it was traced over a first path along the surface of a physical object, converting the first acceleration-based path data set to a first position-based data set including position data for the accelerometer as it was traced over the first path along the surface of the physical object, and generating a three dimensional object model data set based, at least in part on the position data of the first position-based data set.

Abstract: A biosensor includes a PPG circuit that emits light directed at living tissue at a plurality of wavelengths. A first and second spectral response of light reflected from the tissue is obtained around a first wavelength and a second wavelength. Using absorption coefficients for substances at the plurality of wavelengths, concentration levels of a plurality of substances such as Nitric Oxide may then be determined from the spectral responses.

Abstract: The present invention relates to a device, system and a method for extracting physiological information indicative of at least one vital sign of a subject from detected electromagnetic radiation reflected from the subject.

Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.