Means For Intermixing Liquid With Solid Or Different Liquid Patents (Class 604/82)
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Publication number: 20090012464Abstract: This invention pertains to a hose system for an injector for injecting contrast agents and saline solution into the human body. The hose system comprises a contrast agent conduit (106, 126; 206, 226; 306, 326; 401, 402,403, 404, 405, 421, 422, 423, 424, 425; 501, 502, 503, 504, 521, 522, 523, 524), a saline solution conduit (116, 216, 316, 411, 412, 413, 414, 415; 511, 512, 513, 515) a pump hose (132; 232; 332; 432; 532) and a frame (135; 235; 335; 435, 436; 535, 536, 537). The contrast agent and saline solution conduits are mechanically fixed at a least one position to the frame. The pump hose is fixed to the frame at least two positions. The invention further pertains to a squeeze valve and a pressure measuring interface.Type: ApplicationFiled: August 24, 2007Publication date: January 8, 2009Inventors: Baecke Martin, Heide Walther, Uwe Schwerdtfeger
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Publication number: 20090012465Abstract: A microcatheter having a distal end with a tip relief region comprising at least one spiral cut, preferably a full thickness cut, and preferably having decreasing pitch towards the distal tip. The microcatheter is preferably made of medical grade superelastic nitinol. The microcatheter can be used alone or as one catheter in a dual lumen microcatheter assembly.Type: ApplicationFiled: May 13, 2008Publication date: January 8, 2009Inventor: Lucas Latini
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Patent number: 7468049Abstract: A dual syringe adapter for attachment to a pair of side-by-side syringes includes three interconnected portions. A first portion is configured so as to snap onto a plunger head portion of each syringe so as to connect the pair of syringes and maintain plunger movement in unison. A second portion of the adapter is configured so as to snap onto a syringe body of each syringe to help maintain the connection of the two syringes. The third interconnected portion is positioned between the first and second portions and when connected prevents relative movement of the plungers into the syringe bodies. Weakened sections allow the connecting portion to be severed from the first and second portions thereby allowing plunger movement into the syringe bodies. Once severed, the connecting portion is secured to syringe tips for dispensing a mixed composition.Type: GrantFiled: June 14, 2005Date of Patent: December 23, 2008Assignee: Rieke CorporationInventor: Richard A. Laveault
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Patent number: 7462164Abstract: This device comprises means for supporting a first and a second chamber, means for allowing these chambers to communicate with each other, and a movable member for applying a suitable force to reduce the volume of the first chamber. The means for supporting the first and second chambers comprise two tubular bodies, each open at one end, the dimensions of these openings being such as to allow these tubular bodies to be brought together and slid one into the other, a double-ended needle, with associated guide means, being interposed between the said chambers in such a way that when the said tubular bodies are slid towards each other, the respective ends of the said needle pass into the chambers and the volume of the chamber is reduced.Type: GrantFiled: October 22, 2004Date of Patent: December 9, 2008Assignee: Ares Trading S.A.Inventor: Andrew Moir
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Publication number: 20080294099Abstract: A sprayer includes a nozzle through which gas is to be ejected with positiveness and uniformity. The sprayer is provided with a nozzle having inner tubes through the interior of which liquid is to pass and an outer tube receiving the inner tubes therein and allowing gas to pass through a space defined with the inserted inner tubes. The inner tubes have respective liquid orifices through which liquids are to be ejected. The outer tube is arranged therein with the liquid orifices and a gas orifice for ejecting gas. When the nozzle is viewed from front, the outer peripheries of the liquid orifices each assume a circular form while the inner peripheries of the gas orifices are differently shaped to provide plural point contact between the outer periphery of the liquid orifice and the inner periphery of the gas orifice.Type: ApplicationFiled: May 13, 2008Publication date: November 27, 2008Applicant: TERUMO KABUSHIKI KAISHAInventors: Teruyuki Yatabe, Koichi Hayakawa, Kenji Yokoyama
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Patent number: 7455657Abstract: Method and apparatus to modify a fluid by passing a compound through a selectively permeable membrane is provided. In one embodiment a fluid moving through a vessel is modified prior to its ejection from the vessel. This may be accomplished by urging the fluid into a mixing chamber wherein the mixing chamber is in fluid communication with an exit orifice and a passageway. This passageway may be in communication with a second chamber through a selectively permeable membrane. The fluid may then be altered by passing a compound between the mixing chamber and the second chamber through the passageway and the selectively permeable membrane. A device for modifying a fluid moving through a vessel may contain a first lumen, a second lumen, an exit orifice, and a mixing chamber in communication with the first lumen and the exit orifice.Type: GrantFiled: June 19, 2001Date of Patent: November 25, 2008Assignee: Boston Scientific Scimed, IncInventors: Wendy Naimark, Susan O'Brien, Brandon Shuman
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Publication number: 20080287866Abstract: The invention features methods, kits, and compositions for the treatment of pain.Type: ApplicationFiled: January 31, 2008Publication date: November 20, 2008Inventor: Adam Heller
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Publication number: 20080275387Abstract: A hemostatic medical device comprising a tubular syringe body extending along an axis and having a front end and a rear end; a plunger axially slidable in the body; a stem projecting axially rearward out of the body from the plunger; a free piston slidable in the body forward of the plunger and subdividing the body forward of the plunger into a front compartment at the front body end and a rear compartment between the plunger and the piston; the syringe body being formed with a mechanism to allow the contents in the rear and front compartments to mix; sterile saline in the rear compartment; and a hemostatic substance in the front compartment.Type: ApplicationFiled: May 3, 2007Publication date: November 6, 2008Inventors: Stephen C. Yeadon, Robert W. Van Holten
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Publication number: 20080269715Abstract: An apparatus for achieving weight loss in a patient is disclosed. The apparatus has a barrier material and an applicator for dispensing the barrier material about the intestine. An injector is used to place the barrier material to block nutrient transfer from the intestine into the blood stream. The barrier material is a polymerizable adhesive that can be injected interstitially between layers of the intestine, or injected into vascular structures to partially block the flow of blood to the nutrient absorbing layers.Type: ApplicationFiled: October 4, 2006Publication date: October 30, 2008Inventors: Craig N. Faller, Robert W. Scott, Bennie Thompson, Wells D. Haberstich, Anil K. Nalagatla, Douglas J. Turner, Donna L. Korvick, Frederick E. Shelton
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Patent number: 7425207Abstract: A vial for dispensing a liquid into a syringe is described which comprises a body section for holding the liquid, the body section having a top and a bottom; a port having a removable seal, where the port is adapted for a syringe connection and where the port is interconnected with the body section at a point near the top of the body section by a passageway which for at least a portion of its length extends above the level of the liquid in the body section when the vial is inverted, thereby preventing leakage of the liquid from the body section when the seal of the port is removed. A method of making the vial is also described.Type: GrantFiled: June 13, 2005Date of Patent: September 16, 2008Assignee: Holopack International Corp.Inventors: Shawn W. Miller, David Rocheleau, Mohammad R. Sadeghi, Walter Zahn, Bernd Hansen
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Publication number: 20080188798Abstract: An injection device for holding and activating a two-chamber ampulla has components whose relative movement causes the pistons of the two-chamber ampulla to be moved in order to mix the substances, as well as devices for injecting the product which is mixed in this way. For this purpose, a receptacle (103) into which the two-chamber ampulla (111) can be inserted and secured is held in a housing (101), and the receptacle (103) can be displaced by means of a carriage (108). A tappet (104) which acts on the pistons (111A, 111B) is movably held in the receptacle (103). A traction cable (114) which is deflected by means of a roller (109) which is mounted on the carriage (108) and one of whose ends is connected to the receptacle (103) and the other end of which is connected to a tension spring (110) which is held on the housing (101) is provided in order to carry out a mixing stroke, insertion stroke, injection stroke and a return stroke.Type: ApplicationFiled: August 31, 2006Publication date: August 7, 2008Applicant: Bayer Schering Pharma AktiengesellschaftInventor: Wilfried Weber
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Publication number: 20080177225Abstract: A medical apparatus includes: a container portion including a space portion filled with a liquid mixed with a bacterium to be injected into a region to be treated, and a gamma-ray shielding portion for shielding gamma rays irradiated in gamma-ray sterilization; a needle tube including a flow passage through which the liquid passes having one end portion in communication with the space portion of the container portion, and the other end portion punctured in the region to be treated; and a pressing operation portion operated in injecting the liquid filled in the space portion of the container portion into the region to be treated.Type: ApplicationFiled: March 27, 2008Publication date: July 24, 2008Inventor: Kanichi Matsumoto
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Patent number: 7402150Abstract: Disclosed is an injection device for properly dissolving pharmaceutical agents contained in a two-compartment syringe having slidable front and rear walls, and then performing portionwise multiple injections. The injection device comprises a front casing designed to enclose and hold the two-compartment syringe with a double-ended needle attached to the front end of it, a rear casing designed to receive the thus held two-compartment syringe being inserted in the rear-end first manner, and to lock and hold the front casing, a piston rod placed in the rear casing and designed to push from behind and carry forward the slidable rear wall, wherein the piston rod can be pushed forwardly from behind the rear casing, and a spring provided so that, when the front end of the piston rod is moved backward, the spring may be once compressed and then push the piston rod to a forward position again, and forwardly drives the slidable rear wall to abut on the slidable front wall.Type: GrantFiled: September 5, 2006Date of Patent: July 22, 2008Assignee: JCR Pharmaceuticals Co., Ltd.Inventors: Hiroshi Matsumoto, Masahiro Urakami, Noriyuki Tanaka, Yoshitaka Yamashita, Shinji Kotani, Takashi Hanada, Masafumi Tatsumi
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Publication number: 20080171971Abstract: A new and enhanced device and technique for mixing and dispensing a preserved agent is disclosed. The syringe-like device employs a novel piston fluid channel allowing for various chambers of the syringe to come into fluid communication when the piston is actuated. More especially, the person administering the preserved agent may visually confirm full resuspension and deliver an accurate dosage of the agent.Type: ApplicationFiled: November 16, 2005Publication date: July 17, 2008Inventors: Paul Mario DiPerna, Steven Donald Kimmell, Jodi Laurel McAlpine
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Patent number: 7396341Abstract: A locking-stressing-mechanism with spring-actuated output drive and a counter with which an apparatus of this kind is fitted, accommodated in a two part housing the two parts of which are mounted to be rotatable relative to each other, can be blocked by means of a pre-stressed leaf spring. The leaf spring is initially accommodated in a recess in the wall of one housing part. As soon as the permitted number of actuations has been reached a push rod pushes the leaf spring out of its resting position. The leaf spring then jumps into a recess in the wall of the other housing part and the two housing parts can no longer be rotated relative to each other. The push rod may be mounted on the pointer of the counter. This blocking device can only be overcome by the application of a force which is sufficient to destroy the device. The device is suitable for blocking a high pressure atomiser or a needleless injector with which a fluid is atomised to form an aerosol or a fluid is injected into a biological tissue.Type: GrantFiled: August 27, 2003Date of Patent: July 8, 2008Assignee: Boehringer Ingelheim International GmbHInventors: Michael Schyra, Herbert Wachtel
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Publication number: 20080161757Abstract: Devices and methods for injecting or otherwise delivering multiple-component therapies to human or animal subjects. Devices having injectors (e.g., syringes) attached to biaxial or coaxial injection cannula(s) are used to deliver multiple components of a particular therapy such that those components become combined shortly before or upon exiting the injection cannula(s). In some embodiments, the injector devices of the present invention may include a first set of finger grips at a first location and a second set of finger grips at a second location. Also, in some embodiments, the injector devices of the present invention may include depth slops for controlling the depth within tissue at which the therapeutic substance is delivered. Also, in some embodiments, the injector devices of the present invention may include refill manifolds with attached syringes or other reservoirs containing the component substances to facilitate refilling of the injectors.Type: ApplicationFiled: January 3, 2008Publication date: July 3, 2008Applicant: Medtronic Vascular, Inc.Inventors: Asha Nayak, Mario Maciel
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Publication number: 20080161756Abstract: The present invention relates to a device for storage and administration of a medicament suspension comprising a container (1) for receiving a medicament suspension wherein the container has two mixing elements (5, 6) which differ with respect to their density such that the first mixing element (5) has a density significantly above the background liquid and significantly above the fully mixed suspension density and the second mixing element (6) has a density significantly below the background liquid and significantly below the fully mixed suspension density.Type: ApplicationFiled: April 28, 2006Publication date: July 3, 2008Applicant: NOVO Nordisk A/SInventor: Dan Noertoft Soerensen
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Publication number: 20080154273Abstract: The present invention relates in certain embodiments to methods, systems, and devices for treating vertebral compression fractures. In one embodiment, a bone cement injector is advanced into bone and injects a bone cement flow through the injector and a vapor flow from at least one vapor outlet in the injector. In another embodiment, the bone treatment system comprises an elongated member having a flow passageway, a bone fill material source, and a vapor source coupleable to the flow passageway. Still another embodiment describes a vapor injection device having an elongated member with a flow passageway, the elongated member configured for insertion into a bone and for delivering a bone fill material through the flow passageway, and having at least one vapor channel in communication with the flow passageway to deliver a vapor into the flow passageway to heat a bone fill material flow.Type: ApplicationFiled: December 10, 2007Publication date: June 26, 2008Inventors: John H. Shadduck, Csaba Truckai
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Publication number: 20080154229Abstract: A delivery device for a bone cement precursor, composites thereof, and support members is provided herein.Type: ApplicationFiled: July 26, 2007Publication date: June 26, 2008Applicant: Lambert Systems, L.L.C.Inventor: Kenneth L. Lambert
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Publication number: 20080121657Abstract: A number of surgical devices for the mixing and dispensement of a dual component surgical adhesive onto tissue are described. The surgical devices can provide adhesive storage chambers for the adhesive components within the surgical device and can have removable cartridges that draw and mix and apply the adhesive onto tissue. The removable cartridges can be easily replaced when clogged with set adhesive. Alternately, an adhesive dispensing device can comprise an adhesive dispensing gun containing the dual components of the adhesive and a plurality of rotatable orifices that can dispense the adhesive. One orifice can be selected and aligned with the adhesive dispensing gun to mix and apply the adhesive onto tissue. A fresh orifice can be rotated into alignment with the gun should a prior orifice become blocked.Type: ApplicationFiled: November 10, 2006Publication date: May 29, 2008Inventors: James W. Voegele, Jessica M. Liberatore
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Publication number: 20080097389Abstract: A-type blood transfusion set having a blood limb, a saline limp and common limb and a one-way saline valve provided in the saline limb which only allows fluid within the saline limb to flow toward the Y connector. The blood limb and saline limb are color coded or marked with some type of identification so that, prior to coupling the blood limb to a source of blood or the saline limb to a source of saline, visual identification of the saline limb, having the one-way saline valve therein, can be readily achieved.Type: ApplicationFiled: July 10, 2006Publication date: April 24, 2008Inventor: Roland B. Wilson
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Patent number: 7351221Abstract: A system for dispensing a medium includes at least a first container to hold the medium, a pressurizing device, such as a pump, in fluid connection with the container for pressurizing the medium, and an agitation mechanism or device to maintain the components of the medium in a mixed state. The container and the pressurizing device can be separate units, as in the case of an bag or bottle in fluid connection with a peristaltic or other type of pump. The container and the pump can also be combined in a single unit, as in the case of a syringe, wherein the syringe barrel of the syringe acts to contain the medium and the syringe plunger pressurizes the medium within the syringe barrel. A method of injecting a multi-component medium includes the step of agitating the medium (for example, as described above) before or during an injection procedure to maintain the components of the medium in a mixed state.Type: GrantFiled: March 31, 2006Date of Patent: April 1, 2008Assignee: MEDRAD, Inc.Inventors: Frederick W. Trombley, III, Arthur E. Uber, III, Edward J. Rhinehart, Rosemary Almon-Martin, Alan D. Hirschman
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Publication number: 20080027375Abstract: The invention is directed to a fluid mixture delivery instrument which excludes entry of air during fluid delivery. The instrument has a main chamber part and a plurality of branch pipes which extend in different directions from the chamber part. The branch pipes are configured with slitted rubber stoppers with closures to which connection tubes can be inserted for the delivery of fluid with exclusion of air.Type: ApplicationFiled: July 24, 2007Publication date: January 31, 2008Applicant: TYCO HEALTHCARE GROUP LPInventors: Ichiro Kitani, Yosuke Sakai, Norifumi Fujiwara
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Patent number: 7322956Abstract: System for mixing four components including a first syringe arrangement and a second syringe arrangement each with two chambers for holding components. Each of the two respective chambers of the syringe arrangements are connected in a uniquely defined fashion due to specific means for connecting the syringe arrangements. A component held by one chamber is mixed with a component of the corresponding other chamber by transfer into the other chamber. After mixing and disconnecting the second syringe arrangement from the first syringe arrangement, the two component mixtures in the chambers of the first syringe arrangement are further mixed and discharged by means of a mixing device which is to be connected to the first syringe arrangement. The connecting means allows connecting of the mixing device to the first syringe arrangement only after removal of the second syringe arrangement and a portion of the connecting means.Type: GrantFiled: July 14, 2004Date of Patent: January 29, 2008Assignee: Straumann Holding, ABInventors: Daniel Fehr, Astrid Neidhardt, Christian Damm
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Patent number: 7311692Abstract: A dual-chamber type prefilled syringe comprises a cylindrical body within which a front plug member, a middle plug member and an end plug member are hermetically fitted to form a first chamber and a second chamber. The cylindrical body has an inner surface formed with a bypass. When the middle plug member moves to a position where the bypass is formed, the first chamber is communicated with the second chamber for the first time via the bypass. In this beginning state of liquid transfer (S), an inner volume (VS) of the cylindrical body between a leading end of the cylindrical body and a rear end of the front plug member is set to be at least 60% of a volume (VC) of a second component. When liquid component within the second chamber flows into the first chamber, it is possible to prevent part of the liquid component from passing through the first chamber to reach a portion for attaching an injection needle at a leading end of the cylindrical body.Type: GrantFiled: February 18, 2004Date of Patent: December 25, 2007Assignee: Takeda Pharmaceutical Company LimitedInventors: Masahiko Kato, Yasaburo Akagi
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Patent number: 7303542Abstract: A mixing/charging port for medical treatment capable of reliably absorbing air bubbles. The mixing/charging port for medical treatment includes a disc-like valve having an insertion hole at the center, a seating for supporting the lower part of the periphery of the valve with the center of the rear surface side of the valve not supported, and a cover for restraining the valve by covering at least the upper part of the periphery of the valve with the center on the front side surface of the valve left uncovered, wherein a fitting hole defined by an inner periphery of the cover works as an anchor for anchoring an insertion body to the mixing/charging port by fitting the insertion body to the fitting hole when the insertion body is inserted into the insertion hole; and the tip of the depressed part of the valve is brought into contact against the inner bottom surface of the seating when the valve is depressed by the insertion member.Type: GrantFiled: December 30, 2003Date of Patent: December 4, 2007Assignee: JMS Co., Ltd.Inventor: Ryoji Fujii
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Patent number: 7294119Abstract: A syringe system for the administration of lyophilized drugs includes a syringe barrel and a stopper and a needled guard each coupled with the syringe barrel. A reconstitution plunger is removably coupled with the stopper. A diluent is withdrawn from the syringe into a vial containing a lyophilized drug, and the diluent and drug are mixed to form a therapeutic agent. The reconstitution plunger is then replaced by an administration plunger. The length of the reconstitution plunger is greater than the length of the administration plunger in order to prevent activation of the needle guard during reconstitution. Alternatively, a single plunger system may be used in which the plunger can transition from an extended length during reconstitution to a shortened length during administration. During administration, a radial element of the plunger contacts latch members of the needle guard, whereupon the shield advances to an extended position covering the needle.Type: GrantFiled: June 10, 2004Date of Patent: November 13, 2007Assignee: Safety Syringes, Inc.Inventors: Lars Tommy Westbye, Philip Dowds
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Publication number: 20070255201Abstract: Time-indicating syringe mixing systems for mixing, storing, and dispensing a two-part dental composition that becomes less stable upon mixing including a first plunger comprising an elongate stem and a plug at a distal end of the elongate stem, a hollow first chamber configured to contain a first component, a hollow second chamber configured to contain a second component, means for providing a region of increased space between an outside surface of the elongate stem of the first plunger and an interior surface of a wall defining the hollow first chamber, and means for protecting a recorded mixing and/or expiration date from damage or alteration. The inventive syringe mixing systems may be configured as syringe-in-syringe systems and/or syringe-to-syringe systems.Type: ApplicationFiled: October 2, 2006Publication date: November 1, 2007Applicant: Ultradent Products, Inc.Inventors: Bruce S. McLean, Dan E. Fischer
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Publication number: 20070255202Abstract: A liquid mixing infusor includes a main body defining an internal chamber and has an upstream port, a downstream port and a confluent port. Each port is fluidly couplable with the internal chamber. A valve may be mounted within the internal chamber of the main body and is adapted for rotational movement between a blocking position interrupting fluid flow between the confluent port and one of the upstream port and the downstream port and between the upstream port and the downstream port, and a flow position permitting fluid flow between the upstream port and the downstream port. A manually manipulative member is mounted relative to the main body and operatively connected to the valve. The manipulative member is movable to cause corresponding movement of the valve between the blocking position and the flow position.Type: ApplicationFiled: April 27, 2007Publication date: November 1, 2007Applicant: Nippon Sherwood Medical Industries, Ltd.Inventors: Ichiro Kitani, Shigeaki Funamura
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Patent number: 7270654Abstract: A delivery catheter for delivering material(s) into the body of a mammal can include a first elongated member and a second elongated member. At least a portion of the second elongated member can be slidably disposed within a lumen of the first elongated member. The delivery catheter can mix two materials and then introduce the mixed materials into the body of a mammal.Type: GrantFiled: September 30, 2003Date of Patent: September 18, 2007Assignee: Boston Scientific Scimed, Inc.Inventors: John A. Griego, Marcia Buiser, Carla M. Wiese
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Publication number: 20070191764Abstract: A system for removing or tranferring a pharmaceutical product from a reservoir including an ampoule with a moveable piston therein and an adaptor which includes, generally along a longitudinal axis, a reservoir connector and an ampoule connector for coupling to the ampoule, wherein the ampoule connector includes at least one locking mechanism which, in a side wall, includes a resilient element generally corresponding to a portion of the side wall which extends along the periphery thereof and, at opposing ends, merges with the side wall.Type: ApplicationFiled: February 15, 2007Publication date: August 16, 2007Inventor: Rudolf Zihlmann
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Patent number: 7244248Abstract: A fluid mixing unit insertable along conveyance and/or distribution lines, particularly for mixing diagnostic or medical fluids or the like along biomedical lines, comprising a body that is internally hollow and is provided with at least one pair of intake ports for introducing two fluids to be mixed, which are associable with respective feeder devices, and a discharge port for discharging the mixture of the two fluids, which is associable with an outflow device, and a duct for the flow and mixing of the two fluids that is formed in the body and is connected to the intake ports and to the discharge port.Type: GrantFiled: November 3, 2003Date of Patent: July 17, 2007Assignee: Sidam Di Azzolini Graziano E C. S.A.S.Inventor: Graziano Azzolini
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Patent number: 7217254Abstract: A device for application of material to a surface, for example, biocompatible material to a tissue surface in a medical or clinical setting, is adapted to receive one or more biocompatible materials and one or more sources of pressurized medical gas, and to deliver these biocompatible materials via the medical gas(es) to a tissue surface or other surface. A regulation system controls flow of medical gas at a variety of pressures, and flow of biocompatible agent or agents, allowing agents to be sprayed or otherwise deployed onto a tissue surface. Switching apparatus operably connected to the regulation system directs a set of preset treatment positions allowing sequential application of biocompatible materials under various conditions in conjunction with an overall treatment protocol. The device can be used to apply a photoinitiating primer and polymeric sealant to a tissue surface, followed by light activation to form a polymer coating on the surface.Type: GrantFiled: September 20, 2002Date of Patent: May 15, 2007Assignee: Genzyme CorporationInventors: John M. Kirwan, Joseph Jeffrey Kablik
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Patent number: 7207969Abstract: A filling device and method, particularly for two-component sealants such as fibrin sealants, which enables two fluids to be separately and directly filled to the reservoirs of a dual syringe fluid applicator from two storage containers, which can be standardized, sealed, sterilized bottles. The device has a connector which engages with the fluid applicator, is keyed to orient the applicator's fluid reservoirs in a predetermined manner and holds the containers in side-by-side alignment with the applicator. Two fluid conduits whose downward ends may be pointed to pierce seals on the bottles, extend between the applicator and the bottles and can each have a transverse reach to accommodate the girth of the bottles. The bottles may be tilted by the device to enable the conduits to draw maximal fluid from a lowermost point of the bottle. Tilting can be effected by a downward movement of the device supporting the applicator which movement can introduce the fluid conduits into the bottles.Type: GrantFiled: December 2, 2002Date of Patent: April 24, 2007Assignee: Baxter International Inc.Inventors: Gordon Howard Epstein, Mitchell E. Levinson, Richard Spero, Adam Hagmann
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Patent number: 7191917Abstract: A metering device or a metering element, in particular for metering substances in the compiling of combinatory material libraries, described as comprising a metering element having a supply vessel, open on one side, for holding the substances to be metered, and a plunger, which is axially displaceable and reversibly seals the opening of the supply vessel and which has at least one, preferably centered metering orifice for metering the substances provided in the supply vessel, the supply vessel and/or the plunger having an accommodation as contact point for a mechanical gripping device. Moreover, a metering method is described.Type: GrantFiled: June 22, 2005Date of Patent: March 20, 2007Assignee: Robert Bosch GmbHInventors: Thomas Brinz, Jane Lewis, Markus Tiefenbacher, Thomas Geiger
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Patent number: 7156835Abstract: A process and apparatus for one-step preparation of fibrinogen adhesive by polyethylene glycol-mediated precipitation from plasma are disclosed. The methods and apparatus of the invention permit preparation of autologous fibrinogen adhesive composition from the patient during surgery, and can be applied generally to provide such compositions. Also disclosed are an apparatus and method for application of sealant comprising this fibrinogen adhesive composition.Type: GrantFiled: February 5, 2002Date of Patent: January 2, 2007Assignee: Baxter International Inc.Inventor: Gordon H. Epstein
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Patent number: 7104971Abstract: The invention relates to an injector device for delivery of liquid from a high pressure source, and also to a method of performing such an injection. The device comprises a storage chamber 6, for the liquid or the liquid precursor components, comprising a storage barrel 16 with at least a section of substantially constant cross-section, defining a storage chamber axis, and a pressure chamber 4 comprising a pressure barrel 10 of substantially constant cross-section, defining a pressure chamber axis, for accommodation of at least one piston therein and having a front end opening 14 for ejection of the liquid. The pressure chamber being of sufficient strength to sustain the liquid pressure.Type: GrantFiled: February 14, 2006Date of Patent: September 12, 2006Assignee: Pharmacia ABInventor: Birger Hjertman
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Patent number: 7083606Abstract: The present invention provides apparatus for rapid pediatric resuscitation and/or emergency management. A standardized formulation of each commonly used resuscitation medication in a self-contained set-up along with commonly used medical equipment for use in resuscitation procedures is provided.Type: GrantFiled: August 28, 2002Date of Patent: August 1, 2006Inventor: S. Lee Fineberg
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Patent number: 7081103Abstract: A filling device for connecting a dispensing instrument having multiple fluid reservoirs to multiple containers is disclosed. More particularly, the present invention discloses a connecting device capable of coupling the individual reservoirs of a dispensing instrument to multiple fluid containers. The apparatus includes a body, a collar extending from the body, a plurality of tubes in fluid communication with a plurality of inlet ports formed in the body, and a hood adapted to simultaneously receive a plurality of containers therein. The containers are positioned within the hood to allow the plurality of tubes to simultaneously and separately draw fluid from the fluid containers and transferring the material into the individual reservoirs of the dispensing instrument.Type: GrantFiled: November 4, 2002Date of Patent: July 25, 2006Assignee: Baxter International Inc.Inventors: Gordon Howard Epstein, Mitchell E. Levinson, Richard Spero
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Patent number: 7077827Abstract: A syringe for sequentially administering different fluids includes a floating piston which separates the syringe into a first portion for receiving a first fluid to be administered and a second portion for receiving a second fluid to be administered. The floating piston includes a fluid tight seal which initially separates the first and second portions of the syringe and apparatus for connecting the second portion of the syringe to the syringe needle after the first fluid has been discharged from the syringe.Type: GrantFiled: February 27, 2004Date of Patent: July 18, 2006Inventor: Christian John Greenfield
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Patent number: 7077835Abstract: A device for reconstituting liquid for medical use by bringing together a first liquid medium contained in a first vessel in the form of a cartridge (3) and a second medium, such as a drug in solid form, contained in a second vessel in the form of a vial (7), the device (19) comprising means (41) for supporting the first and second vessels, and a movable operating member (50) for applying a force to cause the first liquid medium to be delivered at a controlled rate from the first vessel into the second vessel. The first and second vessels may be provided in a pack (70) having liquid transfer means in the form of a needle (10).Type: GrantFiled: December 10, 2001Date of Patent: July 18, 2006Assignee: Applied Research Systems ARS Holding N.V.Inventors: Grenville Arthur Robinson, Michael Anthony Hobbs, Martyn Omar Rowlands, John Richard Calvert
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Patent number: 7060049Abstract: A system for dispensing a medium includes at least a first container to hold the medium, a pressurizing device, such as a pump, in fluid connection with the container for pressurizing the medium, and an agitation mechanism or device to maintain the components of the medium in a mixed state. The container and the pressurizing device can be separate units, as in the case of an bag or bottle in fluid connection with a peristaltic or other type of pump. The container and the pump can also be combined in a single unit, as in the case of a syringe, wherein the syringe barrel of the syringe acts to contain the medium and the syringe plunger pressurizes the medium within the syringe barrel. A method of injecting a multi-component medium includes the step of agitating the medium (for example, as described above) before or during an injection procedure to maintain the components of the medium in a mixed state.Type: GrantFiled: May 12, 2003Date of Patent: June 13, 2006Assignee: Medrad, Inc.Inventors: Frederick W. Trombley, III, Arthur E. Uber, III, Edward J. Rhinehart, Rosemary Almon-Martin, Alan D. Hirschman
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Patent number: 7033337Abstract: The invention relates to an injector device for delivery of liquid from a high pressure source, and also to a method of performing such an injection. The device comprises a storage chamber 6, for the liquid or the liquid precursor components, comprising a storage barrel 16 with at least a section of substantially constant cross-section, defining a storage chamber axis, and a pressure chamber 4 comprising a pressure barrel 10 of substantially constant cross-section, defining a pressure chamber axis, for accommodation of at least one piston therein and having a front end opening 14 for ejection of the liquid. The pressure chamber being of sufficient strength to sustain the liquid pressure.Type: GrantFiled: May 20, 2004Date of Patent: April 25, 2006Assignee: Pharmacia ABInventor: Birger Hjertman
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Patent number: 7018357Abstract: An external mixer assembly is provided which externally mixes and delivers a first and a second component of a biological adhesive to tissues or organs for sealing wounds, stopping bleeding and the like. The first and second components are mixed immediately after exiting from separate outlet ports disposed in fluid communication with component reservoirs. In on embodiment, the external mixer assembly includes a housing having a housing head for enclosing therein a first reservoir containing the first component, and a second reservoir containing the second component. The housing further includes a discharge nozzle defining a longitudinal axis for enclosing therein a conduit assembly having a first and a second conduit in communication with the first and second reservoir, respectively. A deflector assembly is connected to the discharge nozzle. The deflector assembly includes a deflector plate to provide a space for initial mixing of the first and second components.Type: GrantFiled: February 27, 2002Date of Patent: March 28, 2006Assignee: Tyco Healthcare Group LPInventor: Clifford L. Emmons
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Patent number: 6994686Abstract: A delivery device applies a biocompatible and biodegradable barrier material to a tissue region, e.g., to seal a vascular puncture site. The material comprises two liquid components, which are pre-packaged in individual dispensers. Upon mixing, the liquid components cross-link to create a barrier matrix. A holder attaches to the delivery device. The holder mutually supports the first and second dispensers while the protein solution and polymer solution are conveyed from the dispensers into a fluid delivery channel. The protein and polymer solutions mix as a result of flow through the channel.Type: GrantFiled: February 28, 2001Date of Patent: February 7, 2006Assignee: NeoMend, Inc.Inventors: Gregory M Cruise, Olexander Hnojewyj
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Patent number: 6960183Abstract: A veterinary pill/capsule delivery device comprised of a dispensing head for holding a pill or capsule, the dispensing head being attached to the end of a syringe component for ejecting the pill or capsule out from the dispensing head into the animal's mouth while at the same time injecting a quantity of water into the mouth. The syringe component includes a push-rod that protrudes into dispensing head for ejecting the pill/capsule therefrom, plus water release holes near the dispensing head for simultaneously jetting water out of the syringe component into the animal's mouth, thereby compelling the animal to swallow the pill.Type: GrantFiled: December 2, 2003Date of Patent: November 1, 2005Inventor: Jon R. Nicolette
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Patent number: 6942639Abstract: The delivery system of the present invention is comprised of at least two chambers which store, individually, an activated blood component and an inactivated blood component. The first chamber comprises an activating agent and a filter which may be one in the same thus allowing the formed clot to be triturated thereby isolating the thrombin from the clot. The second chamber stores the inactivated blood component that when mixed with thrombin will produce a gel. The first or second chamber may further contain agents which are desired to be delivered to a specific site. The unique design of the delivery system allows for ease in operation of combining two agents at a specific time and place.Type: GrantFiled: April 9, 2001Date of Patent: September 13, 2005Assignee: Medtronic, Inc.Inventors: Robert F. Baugh, Lisa M. Lim, Julie S. Eaton, John G. Rivera, Victor D. Dolecek
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Patent number: 6939329Abstract: Apparatus for supporting a syringe (6, 10) includes a handle portion (2) and a cradle (4). A clip (14) is provided for connecting the plungers (8) of two or more syringes (6, 10), and two or more syringes (6, 10) are operated by placing one (6) in the cradle (4) and attaching the clip (14) to the plungers (8) for simultaneous operation of the plungers (8). The handle portion (2) also forms a cavity for storing the clips (14). The apparatus is preferably used in combination with an applicator tip (12) that combines the outputs from the two or more syringes (6, 10).Type: GrantFiled: October 6, 2000Date of Patent: September 6, 2005Assignee: Harvest Technologies CorporationInventor: Wesley H. Verkaart
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Patent number: 6936033Abstract: A double syringe delivery system is disclosed for holding a pair of syringes in a manner so as to accommodate the simultaneous activation of the plunger of each syringe in order to effect simultaneous delivery of the contents of each syringe. The delivery system includes a delivery mechanism for delivering the contents of both syringes to a site of application. The delivery system further includes a support member that is positioned between the two syringe bodies. The elongated support member has resilient, C-shaped clamps on one end of the support member. The clamps are designed to be removably clamped onto the applicator so that the syringe barrels will be held together in a parallel manner. The elongated support member further comprises finger grips. A plunger connects the two syringe plungers so that they can also be simultaneously activated.Type: GrantFiled: August 5, 2002Date of Patent: August 30, 2005Assignee: Medtronic, Inc.Inventors: Kevin D. McIntosh, Richard M. Albrecht
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Patent number: 6932791Abstract: A microinjection system comprises a device for housing dried forms of medical reagents, such as vaccines, hormones, etc. in single doses. Within a single chamber, a dry reagent bed is provided adjacent a compression component that keeps the bed compacted. In operation, diluent flows through the chamber to carry the reagent out of the chamber in fluid form. In the illustrated embodiments, the fluid carrying reagent is directly delivered from the chamber via a needle. Integral or connectable diluent delivery devices are disclosed for providing an appropriate volume of diluent to the reagent chamber. Unstable formulations of drugs, for example, can be safely stored in dry form. When injection is needed, the drug can be delivered almost instantly in fluid form simply by releasing diluent through the chamber, where the reagent bed is dissolved or suspended while the remaining reagent is continually compacted.Type: GrantFiled: May 12, 2003Date of Patent: August 23, 2005Assignee: Prismedical CorporationInventor: Michael A. Taylor