Means For Intermixing Liquid With Solid Or Different Liquid Patents (Class 604/82)
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Publication number: 20140323963Abstract: An injection device is provided with dual medicament chambers and a mixing pen needle assembly, whereby predetermined dosages of two medicaments can be provided to a mixing reservoir in the pen needle assembly and delivered simultaneously with the injection device.Type: ApplicationFiled: April 24, 2013Publication date: October 30, 2014Applicant: Becton, Dickinson and CompanyInventor: Robert E. West
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Patent number: 8870846Abstract: A device for priming and venting a hazardous drug within an intravenous administration set. The device includes various access ports and fluid channels to permit direct injection of a hazardous drug into the fluid reservoir, while eliminating the possibility of undesirable exposure to the hazardous drug. The device further includes priming and flushing ports to enable flushing of a hazardous drug from the system following an infusion procedure.Type: GrantFiled: January 10, 2013Date of Patent: October 28, 2014Assignee: Becton, Dickinson and CompanyInventors: Bryan G. Davis, Minh Quang Hoang
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Patent number: 8870028Abstract: A dispensing device is disclosed having an ampoule with at least four storage lumens extending axially along the length of an ampoule body, a mixing tip coupled to a distal end of the storage lumens, the mixing tip having at least four gasket seats formed therein, each gasket seat corresponding to one of the storage lumens, and an outlet lumen in fluid communication with the storage lumens.Type: GrantFiled: January 10, 2013Date of Patent: October 28, 2014Assignee: Restek CorporationInventors: Thomas E. Kane, Brian A. Jones
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Patent number: 8858063Abstract: A dilution kit for and a method of diluting concentrated solutions used to treat allergic symptoms are disclosed. The dilution kit may comprise a case comprising: a base; and a cover hingedly coupled to the base. A foam pad may be removably coupled within the base, the foam pad defining a plurality of vial apertures. A plurality of vials may be removably positionable within the plurality of vial apertures. The method may comprise: removably positioning at least one of a plurality of vials in an upwardly facing position within at least one of a plurality of apertures defined in a layer of foam padding in a base of a case of a dilution kit; and placing a predetermined amount of one of a diluent, a concentrated solution, and a combination thereof into at least one empty vial of the plurality of vials.Type: GrantFiled: April 3, 2009Date of Patent: October 14, 2014Assignee: SAPA-IP, LLCInventor: Stuart H. Agren
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Patent number: 8845580Abstract: A delivery system for delivering a shear-sensitive injectable material into the body of a mammal, such as a human being, acts as a mechanical feed that continuously mixes a shear-sensitive injectable material as it delivers the shear-sensitive injectable material to a target tissue, or to a site adjacent a target tissue. In one embodiment of the invention, the delivery system comprises an injector system including a rotatable mixing member coupled to a driving system. The injector system comprises a housing defining a lumen and having an output end and a driving system connection end and includes a rotatable mixing member for coupling to the driving system and for mixing and delivering the shear-sensitive injectable material. The driving system comprises a drive mechanism, an actuator capable of actuating the drive mechanism, and an interfacing member coupled to the drive mechanism for coupling with the mixing member to rotate the mixing member when the interfacing member is driven by the drive mechanism.Type: GrantFiled: January 14, 2004Date of Patent: September 30, 2014Assignee: Boston Scientific Scimed, Inc.Inventor: Barry N. Gellman
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Publication number: 20140276384Abstract: Described are devices, systems, and methods for processing adipose tissue for reintroduction into a body. In some embodiments, adipose tissue is mixed with an additive prior to reintroduction.Type: ApplicationFiled: March 11, 2014Publication date: September 18, 2014Applicant: Allergan, Inc.Inventors: Justin Schwab, Mike Augarten, Darin Messina, Jason Metzner, Ethan Franklin
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Publication number: 20140276637Abstract: A syringe device that includes a stem, container, and a plunger, the plunger having tubes with a soluble substance that maintain a seal on compounds within the container's chamber, and/or a parabolic cover held in position by a soluble substance, thus allowing a multi-cycle usage to dispense medication to patients, even while preventing further use.Type: ApplicationFiled: March 14, 2013Publication date: September 18, 2014Inventor: Leonard Allen Massey, JR.
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Patent number: 8834449Abstract: A movable mixing disc is inserted into a regular syringe. The mixing disc has a small hole covered by a fine screen, allowing only saline solution to get behind the disc. When the plunger of the syringe is pressed, the saline solution emerges from the mixing disc hole as a high velocity jet, stirring up the settled particles. As the ejection continues, the mixing disc is pushed forward by the plunger in order to eliminate any unused volume.Type: GrantFiled: February 28, 2012Date of Patent: September 16, 2014Assignee: Ikomed Technologies, Inc.Inventors: Lindsay S. Machan, Daniel Gelbart
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Publication number: 20140257179Abstract: A device is provided for introducing into a patient a combination of adipose tissue and an additive, for example, a hydrogel additive. The device includes a fat cartridge, an additive cartridge containing an additive, and a housing configured to receive, in a side-by-side manner, the fat cartridge and additive cartridge. A mixing tip may be included for causing mixing of the cartridge components prior to extrusion from a needle or cannula.Type: ApplicationFiled: March 7, 2014Publication date: September 11, 2014Applicant: Allergan, Inc.Inventors: Justin Schwab, Edwin J. Kayda, Tiago Bertolote
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Patent number: 8829074Abstract: A bone cement is provided that includes a solid component and a liquid component. The solid component and liquid component are mixed together to form the bone cement. After completion of the solid and liquid component mixing, the bone cement has an initial viscosity effective for manual application or manual injection onto or into a targeted anatomical location, e.g., bone, and the cement has stable viscosity range that over both time and temperature is effective for uniformly filling the targeted anatomical location, for example an osteoporotic bone or a fractured vertebral body, with minimal to no leakage of the cement from the targeted anatomical location. Additionally, both the initial viscosity and the stable viscosity of the bone cement are within a range that renders the bone cement effective for injection with a manually operated syringe or multiple syringes.Type: GrantFiled: August 29, 2013Date of Patent: September 9, 2014Assignee: DePuy Synthes Products, LLCInventors: Andreas Boger, Christoph Sattig, Stefan Deusser
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Patent number: 8829073Abstract: An implant material on the basis of a polymer system has a first component and a second component that react with one another when mixed to form a polymer-based solid. The first component is a paste that contains at least one biocompatible polymer powder and a starter component for initiating a polymerization reaction upon mixing, wherein the paste has a carrier liquid, wherein under normal conditions in the carrier liquid the at least one biocompatible polymer powder does not dissolve or significantly swell and the starter component remains stable until mixing with the second component of the polymer system. The second component of the polymer system contains at least one reactive organic liquid or a solution or a suspension of a reactive organic liquid and of a polymer.Type: GrantFiled: March 27, 2008Date of Patent: September 9, 2014Assignee: InnoTERE GmbHInventor: Berthold Nies
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Patent number: 8821436Abstract: A fluid transfer device is disclosed and described, the device comprising a housing comprising a first piercing assembly associated with the housing, the first piercing assembly adapted for accessing a first container, the first piercing assembly comprising a first piercing member comprising at least one conduit. A second piercing assembly is associated with the housing, the second piercing assembly adapted for accessing a second container, the second piercing assembly comprising a second piercing member comprising at least one conduit.Type: GrantFiled: October 1, 2010Date of Patent: September 2, 2014Assignee: Yukon Medical, LLCInventors: Theodore J. Mosler, Bryan J. Peters, David L. Foshee, Nathan R. Snell
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Patent number: 8814853Abstract: There are disclosed embodiments of a system for thermochemical tissue ablation. An ablation needle in the form of a cannula with a tip and a plurality of tubes or lumens therethrough is provided, with the tip forming a hollow mixing chamber without external openings. Liquid reagents are passed through the lumens or tubes to the mixing chamber, where an exothermic reaction results, heating the tip. The heated tip is used for tissue ablation. The reaction product can be at least partially evacuated from the mixing chamber through a tube or lumen that empties into a container.Type: GrantFiled: October 28, 2010Date of Patent: August 26, 2014Assignee: Cook Medical Technologies LLCInventor: Christopher D. Bosel
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Patent number: 8814823Abstract: The invention relates to a method and a device for lyophilizing, reconstituting and administering a reconstituted substance. The device has an elongate housing having a dispensing-side front housing end and a housing end lying opposite it. A first chamber, containing a lyophilizate, is disposed in the housing in the region of the front housing end and is tightly sealed at an end facing the front housing end by a removable closure and is tightly sealed in the direction of the rear housing end by a plunger. A second chamber is provided or formed in the housing in the region of the rear housing end which is connected by at least one opening to the ambient atmosphere. This opening is closed by a membrane which is permeable to gas but not to bacteria.Type: GrantFiled: October 25, 2005Date of Patent: August 26, 2014Assignee: Pharma Consult Ges.m.b.H. & Co Nfg KGInventor: Ewald Pickhard
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Publication number: 20140228745Abstract: Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas.Type: ApplicationFiled: March 14, 2014Publication date: August 14, 2014Inventors: Upma Sharma, Rany Busold, Adam Rago, Gregory T. Zugates, Toby Freyman, Lisette Manrique Miller
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Publication number: 20140228805Abstract: A modular injection system enables a user to control the dilution ratio of mixed injectable fluid. In one embodiment, modular injection system includes a handheld injection device operatively connected to a separate control device. In one embodiment, the control device includes a drive unit configured to apply extrusion forces to fluids. In another embodiment, the handheld injection device includes the drive unit. In one embodiment, the modular injection system produces the mixed injectable fluid based on a selected dilution ratio. In one embodiment, the modular injection system produces the mixed injectable fluid based on selected injection rates.Type: ApplicationFiled: April 15, 2014Publication date: August 14, 2014Applicant: Allergan, Inc.Inventors: Christopher S. Mudd, Mitchell H. Babkes, Zachary P. Dominguez, Michael J. Prichard, Martha E. Llewellyn, Shaohui Qiu, Lee F. Powers, Brett R. Johnson, Ahmet Tezel, Corey Josenhans
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Patent number: 8802072Abstract: Biocompatible adhesive materials, such as for use with biological tissues and/or medical implants, are provided, as well as methods and kits for making and using the biocompatible adhesive materials. The biocompatible adhesive materials include a dendrimer component and a polymer component, and may be tailored for specific tissue types and conditions.Type: GrantFiled: April 13, 2012Date of Patent: August 12, 2014Assignee: Massachusetts Institute of TechnologyInventors: Natalie Artzi, Elazer R. Edelman, Núria Oliva Jorge, Maria Carcolé Solanes
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Patent number: 8777479Abstract: A system for use in bone cement preparation can include a chamber for intermixing a liquid monomer and solid polymer components, a container, a vacuum channel, and a filter. The mixing chamber can be configured to hold a non-liquid, polymer powder component of a bone cement. The container can be configured to hold a liquid component of the bone cement. The system can have a first interface disposed between the mixing chamber and the container and a second interface disposed between the mixing chamber and the vacuum channel. The second interface can to receive and position the filter between the mixing chamber and the vacuum channel. The vacuum channel can direct a partial vacuum to draw the liquid component from the container into the non-liquid component in the mixing chamber to intermix the components and to thereby provide a settable bone cement.Type: GrantFiled: October 13, 2009Date of Patent: July 15, 2014Assignee: DFINE, Inc.Inventors: Harry Kwan, Andrew Kohm, Csaba Truckai
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Patent number: 8763861Abstract: A device for dispensing individual components of a two-component adhesive includes first and second manifold members, each having a distribution chamber therein. A set of conveying tubes is supported within the dispensing device and collectively present a predetermined total cross-sectional flow area to the first distribution chamber. The second manifold member has an array of passages therethrough. Each tube extends substantially concentrically through a respective passage to define annular flow spaces that collectively present a predetermined total cross-sectional flow area to the second distribution chamber member. First and second components emanating from the tubes and the flow spaces are able to intermix with and diffuse into each other on the discharge area of the second manifold member. The cross-sectional flow areas presented to the first and second distribution chambers are equal.Type: GrantFiled: December 17, 2010Date of Patent: July 1, 2014Assignee: Actamax Surgical Materials, LLCInventors: James William Ashmead, William Gerald DiMaio
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Publication number: 20140180206Abstract: A catheter device comprising a chamber containing an opacity enhancing substance is disclosed. The opacity enhancing substance is in a dried or semi-dried form within the chamber of the device. Release of a liquid into the chamber suspends the substance and forms an opacity enhancing solution that is released into the lumen of the device in order to enhance the opacity of the device for imaging.Type: ApplicationFiled: February 25, 2014Publication date: June 26, 2014Inventor: Eric K. MANGIARDI
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Patent number: 8757444Abstract: A device for dispensing individual components of a two-component adhesive includes first and second manifold members, each having a distribution chamber therein. A set of conveying tubes is supported within the dispensing device and collectively present a predetermined total cross-sectional flow area to the first distribution chamber. An array of openings and an array of passages extend through the second member. The openings receive the discharge ends of the conveying tubes. The passages are disposed in fluid communication with the second distribution chamber. The passages collectively present a predetermined total cross-sectional flow area to the second distribution chamber member. The openings and the passages are laterally spaced with respect to each other such that the discharge ends of the tubes are interspersed among the passages. The cross-sectional flow areas presented to the first and second distribution chambers are different.Type: GrantFiled: December 17, 2010Date of Patent: June 24, 2014Assignee: Actamax Surgical Materials, LLCInventors: James William Ashmead, William Gerald DiMaio
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Patent number: 8753670Abstract: A fibrin wound dressing is made by mixing quantities of fibrinogen solution and thrombin solution with air. The resulting foam is very light weight, and with the proper attention to the amount of thrombin, is also sufficiently viscous to rest on a vertical surface without dripping. The wound dressing may also be formulated for its ability to continue migration of healing substances, such as PDGF, from the dressing to the wound site. Thrombin substitutes, such as other clotting proteins, may be used instead of thrombin. The resulting foam may also be lyophilized or ground and lyophilized for later reconstitution. A therapeutic drug or other additive may also be added to the wound dressing.Type: GrantFiled: March 26, 2008Date of Patent: June 17, 2014Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventor: Yves A. Delmotte
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Patent number: 8753310Abstract: A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed.Type: GrantFiled: July 18, 2011Date of Patent: June 17, 2014Assignee: Becton, Dickinson and CompanyInventors: Vincent J. Sullivan, Ge Jiang, Matthew S. Ferriter, Kenneth G. Powell, P. Spencer Kinsey, Carl R. Sahi, John M. Polidoro
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Publication number: 20140163464Abstract: Mixing devices and systems are disclosed for storing separate components and for mixing and dispensing those Components on demand. A mixing device includes a syringe having a generally tubular housing formed with a mixing chamber. A plunger is fitted to the tubular housing to form a first syringe. A dispensing syringe is releasably connected to the mixing chamber. At this point each syringe holds a desired amount of a mixture component. The contents of one syringe are passed through the mixing chamber to the other syringe, forming a usually incomplete mixture. The mixture is then passed through the mixing chamber to the other syringe. Multiple passes through the mixing chamber are continued until the desired mixing result is achieved, and the mixture material is contained in the second syringe that is used to thereafter dispense desired amounts of the mixture.Type: ApplicationFiled: December 3, 2013Publication date: June 12, 2014Applicant: Nexmed Holdings, Inc.Inventors: Yiping Wang, William S. Wei, Daniel W. Frank
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Publication number: 20140155819Abstract: Embodiments of the disclosure may include a medical device for delivering medicament to a body of a user. The device may include a connector for channeling a fluid from a fluid source and a device platform configured to receive the fluid via the connector. The device platform may contact the user's body. The device may further include one or more fluid cannulae coupled to and extending from the device platform and configured for insertion into the body. The fluid cannulae may be configured to receive the fluid from the device platform. The device may also include one or more channels configured to channel the fluid through the connector, into the device platform, into the one or more fluid cannulae, and into the body. The device may also include one or more sensors coupled to the device platform and configured for monitoring a parameter of the body.Type: ApplicationFiled: December 3, 2012Publication date: June 5, 2014Applicant: PicoLife TechnologiesInventors: Farid Amirouche, Julien Jonvaux
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SYSTEMS, DEVICES, METHODS FOR DELIVERING HYDROGEL COMPOSITIONS WITH SELF-PURGING TO PREVENT CLOGGING
Publication number: 20140148791Abstract: A hydrogel composition is formed by conveying separate first and second liquid components subject to a selectively applied application pressure P(A) into an outlet path for mixing and discharge. A liquid flushing agent is automatically conveyed into the outlet path subject to a substantially constantly applied purge pressure P(P) when the application of P(A) is interrupted, to continuously flush residual hydrogel composition from the outlet path.Type: ApplicationFiled: February 3, 2014Publication date: May 29, 2014Applicant: Neomend, Inc.Inventors: Peter BARKER, Jr., William Jerome MEZGER -
Patent number: 8728986Abstract: A metering device, a metering element, and a method for operating same, the metering element having a storage container open on one side for receiving the substances to be metered and a plunger which is axially movable and reversibly seals the opening of the storage container and which preferably has at least one centrally located metering opening for metering the substances provided in the storage container, the plunger including a separation device for particles.Type: GrantFiled: June 14, 2012Date of Patent: May 20, 2014Assignee: Robert Bosch GmbHInventors: Thomas Brinz, Jane Lewis, Markus Tiefenbacher, Thomas Geiger
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Patent number: 8728054Abstract: A syringe-carpule assembly comprising first and second carpules, a housing holding the first and second carpules in an end-to-end relationship, an outer hollow plunger rod supported by and slidable relative to the housing, and an inner hollow rod having first and second openings and being slidably arranged inside the outer hollow plunger rod. The inner hollow rod is slidable between first and second positions. The inner hollow rod in the first position has the first opening disposed within the first carpule and the second opening disposed within the second carpule. This allows liquid solvent in the second carpule to flow into the first carpule, which comprises an evacuated chamber containing solid matter that dissolves in the presence of that solvent to form a mixture. The second carpule is then removed and the mixture in the first carpule is injected into the patient.Type: GrantFiled: October 28, 2009Date of Patent: May 20, 2014Assignee: Synchrojet LLCInventor: Steven Schulhof
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Publication number: 20140121647Abstract: A system for storing and dispensing first and second fluids. A syringe, including a first fluid chamber, a second fluid chamber, a first outlet communicating with the first fluid chamber and extending along a first axis; a second outlet communicating with the second fluid chamber and extending along a second axis, the second axis spaced from the first axis by a first distance. A container having first and second compartments separated by at least one wall and configured to store the first and second fluids, respectively, the first compartment having a first port positioned to be fluidicly connected with the first outlet and the second compartment having a second port positioned to be fluidicly connected with the second outlet.Type: ApplicationFiled: December 19, 2013Publication date: May 1, 2014Applicant: NORDSON CORPORATIONInventor: Thomas A. Kirk
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Publication number: 20140114285Abstract: An embodiment of the invention is directed to a bone marrow aspiration device comprising a plurality of syringes, each of which operates in a series of sequential steps to obtain bone marrow of high quality and therapeutic value, i.e., having a high MSC/ml number. An embodiment of the invention preferably comprises three syringes, wherein a first syringe is used to aspirate bone marrow from a subject, a second syringe contains an anticoagulant, and the third syringe contains a mixture of the bone marrow aspirate and the anticoagulant.Type: ApplicationFiled: October 23, 2013Publication date: April 24, 2014Applicant: SpineSmith Partners, L.P.Inventors: Jizong Gao, Michelle Kelly, John B. Rossman, Michael Landry
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Publication number: 20140114240Abstract: A device and a method are proposed for actuating a carpule, in which a piston is displaced in the carpule by means of a ram that is telescopically extensible by rotation, and in this way a liquid medicament formulation is expelled. For carrying out different processes, different operating movements are provided, particularly the operation of an operating element in different directions and/or the operation of different operating elements. This promotes simple, intuitive and safe operation.Type: ApplicationFiled: February 27, 2012Publication date: April 24, 2014Applicant: BOEHRINGER INGELHEIM MICROPARTS GMBHInventors: Thorsten Joedicke, Berthold Lange, Thomas Willms, Ying Yu
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Patent number: 8706198Abstract: A catheter device comprising a chamber containing an opacity enhancing substance is disclosed. The opacity enhancing substance is in a dried or semi-dried form within the chamber of the device. Release of a liquid into the chamber suspends the substance and forms an opacity enhancing solution that is released into the lumen of the device in order to enhance the opacity of the device for imaging.Type: GrantFiled: June 30, 2011Date of Patent: April 22, 2014Assignee: Quali-Med GmbHInventor: Eric K. Mangiardi
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Publication number: 20140107620Abstract: A nozzle for the supply of biological material, in particular tissue cells, having a mixing chamber (11) which is delimited by a proximal end surface (21) and a distal end surface (22) spaced apart from the proximal end surface (21), at least one nozzle opening (23) which is formed in the distal end surface (22), and at least two supply ducts (30, 40, 50) which discharge into the mixing chamber (11). A first supply duct (30) is arranged in the proximal end surface (21) and discharges into the mixing chamber (11) coaxially to the nozzle opening (23) and a second supply duct (40) has an inlet opening (42) which discharges into the mixing chamber (11) laterally, in particular tangentially at the distal end surface (22).Type: ApplicationFiled: October 15, 2013Publication date: April 17, 2014Applicant: ERBE Elektromedizin GmbHInventors: Andreas Fech, Klaus Fischer, Markus Enderle, Mara Szyrach
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Patent number: 8696618Abstract: An injector (10) for injecting a medicament into a patient. The injector includes a container (18) defining a first chamber (22), which contains a fluid therein, and a second chamber (23). The injector also includes an injection conduit (126) configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source (62) is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.Type: GrantFiled: August 13, 2012Date of Patent: April 15, 2014Assignee: Antares Pharma, Inc.Inventors: Thomas E. Kramer, Peter L. Sadowski
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Patent number: 8690866Abstract: An ablation device includes a handle assembly including a distal end and a probe extending distally from the distal end of the handle assembly. The probe includes a heat-transfer portion and at least one fluid-flow path in fluid communication with the heat-transfer portion. The handle assembly includes at least one fluid reservoir in fluid communication with the at least one fluid-flow path and at least one apparatus configured to cause fluid flow between the at least one fluid reservoir and the heat-transfer portion. The probe is configured to apply thermal energy released by an exothermic chemical reaction that occurs when fluid from the at least one fluid reservoir is caused to flow to the heat-transfer portion.Type: GrantFiled: August 23, 2010Date of Patent: April 8, 2014Assignee: Covidien LPInventor: Joseph D. Brannan
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Publication number: 20140094776Abstract: An injection device for automatically combining two substances, including a body and a cartridge displaceably disposed within the body having a first chamber for containing a first substance, a second chamber for containing a second substance, a first stopper displaceably disposed within the cartridge separating the first and second chambers, a second stopper displaceably disposed within the cartridge defining an end of the second chamber. The device also includes a needle hub displaceably disposed within the body having threads thereon for connecting a pen needle to the injection device. The device additionally includes a plunger displaceably disposed within the body, a biasing member, a sleeve, biased by the biasing member and communicating the bias to the plunger, and an activation button radially displaceable with respect to the body to selectively release the sleeve to drive the plunger and automatically mix the first and second substances.Type: ApplicationFiled: May 19, 2011Publication date: April 3, 2014Applicant: BECTON, DICKINSON AND COMPANYInventor: Richard Cronenberg
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Patent number: 8679055Abstract: An automatic administration instrument includes a syringe and a partition wall in the syringe which partitions the syringe into different rooms for respectively holding plural kinds of drug solutions or a drug and a drug solution. A partition-wall driver displaces the partition wall and an injection needle is connected to the syringe. A body cap attached to the administration instrument body so as to cover the injection needle. The syringe, the partition wall, and the body cap are configured such that displacing the partition wall dissolves or mixes the drug solutions or the drug and the drug solution in a state that the injection needle is covered by the body cap.Type: GrantFiled: August 16, 2012Date of Patent: March 25, 2014Assignee: Panasonic CorporationInventors: Tokumi Ishikawa, Tokumi Baba
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Publication number: 20140081203Abstract: In order to reduce the labor associated with the administration of a medication or the like to a patient via a tube, while ensuring that the medication can be administered with at least the same degree of safety and accuracy as in the past, a container for administering a medication is provided with a storage section and a discharge section. The storage section has an inlet. The container for administering a medication is further provided with a sealing part. The sealing part seals the boundary section between the storage section and the discharge section, and opens the boundary section when the storage part is subjected to a force of a prescribed magnitude or greater while a mixture is stored therein. The discharge section can be connected to a tube. In addition to the inlet, the storage section is also provided with an inlet opening/closing part.Type: ApplicationFiled: May 1, 2012Publication date: March 20, 2014Applicant: MORIMOTO-PHARMA CO., LTD.Inventors: Shuji Morimoto, Masao Nozaki, Naomi Kurata
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Patent number: 8673639Abstract: Disclosed is a method for isolating stem cells. The method uses a specially designed apparatus including: a container containing an aspirate; a piston having an outer diameter corresponding to the inner diameter of the container and having at least one through-hole; and a connection tube adapted to feed an enzyme or a washing solution into the container through the through-hole, having a tip connected to the through-hole, and connected to an external tube or another container containing the enzyme or washing solution at the other end thereof. The method includes pulling the piston backward to form a negative pressure in the container containing the aspirate and to allow the enzyme or washing solution to enter the container containing the aspirate through the connection tube and the through-hole of the piston.Type: GrantFiled: November 23, 2009Date of Patent: March 18, 2014Inventor: Hee Young Lee
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Patent number: 8672878Abstract: A syringe for dispensing anesthetic from a cartridge having an interior wall defining a hollow interior sized and shaped for receiving a dose of anesthetic, and a piston. The syringe includes a tubular plunger slidably received in the hollow interior of the tubular cartridge. The plunger has a hollow interior extending between a distal end shaped for engaging the piston and an open proximal end. The syringe includes a plunger rod slidably received in the hollow interior of the tubular plunger. The rod has a sharp distal end adapted to penetrate the piston, a proximal end, and a length extending between the distal end and the proximal end sized so a delivery portion of the rod extends through the piston into the cartridge when the rod is driven through the piston. The delivery portion includes a recess for receiving a buffering agent to reduce acidity of the dose of anesthetic.Type: GrantFiled: April 4, 2012Date of Patent: March 18, 2014Assignee: Covidien LPInventor: Melvin A. Finke
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Patent number: 8672237Abstract: An applicator for mixing and applying multi-component compositions to a work surface, such as two-component surgical sealants, while avoiding clogs, preventing cross-contamination of the components until a point of intended mixing at a location within the apparatus immediately upstream of an application opening in a tip cap, decreasing pressure drop along the applicator to facilitate fluid delivery, and increasing efficiency of mixing of the components. A luer hub sub-assembly having a proximal hub and a distal hub, an elongate, four-lumened cannula, and a spray tip sub-assembly are provided, with interconnections between the sub-assemblies preserving isolation of the fluid components from one another. The tip cap sub-assembly includes registration structure to assure proper alignment between tip cap and tip insert.Type: GrantFiled: June 25, 2010Date of Patent: March 18, 2014Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Daniel E. Roush, Justin Stevens, Atif M. Yardimci
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Patent number: 8672185Abstract: A dispensing cap is disclosed for mixing a primary flowable substance, such as a soap, lotion, or the like, with a small dose of a secondary flowable substance, such as a fragrance. The dispensing cap includes a plurality of reservoirs containing a plurality of secondary flowable substances. Each of the reservoirs is associated with a secondary piston that, when actuated, causes the secondary flowable substance to be expelled from the reservoir into a mixing chamber in the cap, where it is mixed with the primary flowable substance. Upon mixing the two are dispensed together from a dispensing end of the cap. A selector ring is provided to enable the user to select one of the plurality of reservoirs. The selector ring has an actuation flange that aligns with the secondary piston that is associated with the selected reservoir.Type: GrantFiled: February 24, 2011Date of Patent: March 18, 2014Assignee: Colgate-Palmolive CompanyInventors: Brian Glenn Worthington, Lester Greer
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Publication number: 20140074062Abstract: Drug pump devices with syringe or pen-injection configurations may utilize pre-filled drug vials or cartridges; the prefilled vials may be equipped with mechanisms for stirring their contents and/or changing a chemical environment therein to improve therapies. To facilitate combination therapies, multiple drug pump devices may be assembled into a larger system. Lancet insertion devices for use in conjunction with the drug pump devices may feature improved safety characteristics and/or mechanisms for minimizing pain and discomfort.Type: ApplicationFiled: August 6, 2013Publication date: March 13, 2014Inventors: Sean Caffey, Alice Lai, Po-Ying Li
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Patent number: 8668971Abstract: A package with multiple chambers, wherein the inside of the package is partitioned into multiple chambers by a weak seal part(s) formed by sealing one sheet having a heat seal layer in at least one surface thereof and the other sheet having a heat seal layer in at least one surface thereof with the heat seal layers facing each other and sealing the peripheral edge parts thereof, and heat-pressing, from the outside of the package, a part of the inner surfaces of the walls of the package with the heat seal layers. The package is characterized in that both of two heat seal layers forming the inner surfaces of the walls include only a cyclic polyolefin resin as a resin ingredient.Type: GrantFiled: March 11, 2004Date of Patent: March 11, 2014Assignee: Fujimori Kogyo Co., Ltd.Inventors: Toyoaki Suzuki, Koichi Miura
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Publication number: 20140066845Abstract: In one embodiment, the handheld injection device includes a first housing having a first axis and a second housing having a second axis. In one embodiment, the second housing is configured to support a needle. In one embodiment, the first axis and a second axis form an adjustable angle between about 180 degrees and about 90 degrees.Type: ApplicationFiled: November 12, 2013Publication date: March 6, 2014Applicant: Allergan, Inc.Inventors: Christopher S. Mudd, Mitchell H. Babkes, Zachary Dominguez, Michael J. Prichard, Martha E. Llewellyn, Shaohui Qiu, Lee F. Powers, Brett R. Johnson
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Publication number: 20140052059Abstract: A device is provided for introducing into a patient a combination of adipose tissue and an additive, for example, a hydrogel additive. The device includes a fat cartridge, an additive cartridge containing an additive, and a housing configured to receive, in a side-by-side manner, the fat cartridge and additive cartridge. A mixing tip may be included for causing mixing of the cartridge components prior to extrusion from a needle or cannula.Type: ApplicationFiled: August 14, 2013Publication date: February 20, 2014Applicant: Allergan, Inc.Inventors: Justin Schwab, Edwin Kayda
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Publication number: 20140039386Abstract: The present invention relates to safety delivery systems for intracameral administration of an appropriate dose of cefuroxime subsequent to cataract and other eye surgery. A preferred embodiment of an cefuroxime safety delivery system according to the invention comprises (a) a perforable sterile vial sterile-filled with a measured amount of cefuroxime, (b) a reconstitution syringe with a male luer fitting sterile-filled with 0.1 ml of isotonic salt solution per mg cefuroxime in the perforable vial and a vial adapter with a female luer fitting or one or more needles with female luer fitting, and (c) one or more sterilized delivery syringes with male luer fitting, each delivery syringe being capable of holding at least 0.1 ml of ejectable liquid and containing a marking indicating a fill volume of 0.1 ml of ejectable liquid.Type: ApplicationFiled: February 14, 2012Publication date: February 6, 2014Applicant: CIS Pharma AGInventor: Rolf Schäfer
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Patent number: 8641661Abstract: A system includes a cylinder having a bore with a piston disposed therein, the piston moveable along the bore of the cylinder and having a passage therethrough. The system also includes a mixer disposed in the passage in the piston and including at least one porous mixing device, the at least one porous mixing device comprising a three-dimensional lattice defining a plurality of tortuous, interconnecting passages therethrough, and having physical characteristics to sufficiently mix the first and second components, which characteristics include a selected one or more of mean flow pore size, thickness and porosity.Type: GrantFiled: January 4, 2011Date of Patent: February 4, 2014Assignees: Baxter International Inc., Baxter Healthcare SAInventor: Yves A. Delmotte
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Systems, devices, methods for delivering hydrogel compositions with self-purging to prevent clogging
Patent number: 8641662Abstract: A hydrogel composition is formed by conveying separate first and second liquid components subject to a selectively applied application pressure P(A) into an outlet path for mixing and discharge. A liquid flushing agent is automatically conveyed into the outlet path subject to a substantially constantly applied purge pressure P(P) when the application of P(A) is interrupted, to continuously flush residual hydrogel composition from the outlet path.Type: GrantFiled: April 5, 2011Date of Patent: February 4, 2014Assignee: Neomend, Inc.Inventors: Peter Barker, Jr., William Jerome Mezger -
Publication number: 20140031795Abstract: A delivery system comprising a covering having at least two compartments is provided. A first compartment contains a first therapeutic agent and the second compartment can be unfilled and is configured to receive a second therapeutic agent. The first compartment and the second compartment are separated by at least one removable separation member, for example a drawstring, that can be pulled to allow the first and second therapeutic agents to mix prior to delivery at a selected surgical site. Either the first or second compartment of the covering define an opening further comprising a pre-attached sealing member, which can be a flap sealable by heat, sutures, pressing or interference fittings. The opening of the empty compartment can be configured to receive a filling member, such as a funnel fitted with a spring loaded clip for temporary attachment to the covering. A method of treating a bone defect in a patient utilizing the delivery system is also provided.Type: ApplicationFiled: July 25, 2012Publication date: January 30, 2014Applicant: Warsaw Orthopedic, Inc.Inventor: William F. McKay