Abstract: Methods and systems of enhancing an electronic interaction between a behavioral-modification program and a user in the program by providing customized content specific to the user. The systems and methods allow for coach-counselor assistance to the individual-user or for automated content delivery.

Abstract: A computer-implemented method of heart rate estimation includes receiving heart beat data, detecting sequential beats within the heart beat data, identifying a beat interval of each sequential beat, and generating a beat array containing the beat intervals of sequential beats within an array window. The beat array is then sorted based on the beat intervals of the sequential beats so as to generate a sorted beat array. A weight array is calculated by applying a weight control parameter to each beat interval in the sorted beat array, wherein the weight array includes a weight value for each beat interval that is proportional to a corresponding beat interval value in the sorted beat array. A weighted median is calculated based on the weight array, and a heart rate estimation for the array window is determined based on the weighted median of the weight array and the sorted beat array.

Abstract: An apparatus includes left and right shoe sensor systems. A shoe sensor system includes pressure sensing elements, an accelerometer, and a control circuit that includes a power source circuit, a clock circuit, a processing module, memory, a wireless communication transceiver, sensor communication links, and an accelerometer communication link. The processing module samples data from the pressure sensing element to produce foot force data and samples data from the first accelerometer to produce three-dimensional foot data. The wireless communication transmits as outbound radio frequency (RF) signals regarding the foot force data and the three-dimensional foot data.

Abstract: A pilot tone device for acquiring physiological data of a patient and a magnetic resonance tomography system with a corresponding pilot tone device are provided. The pilot tone device has a pilot tone transmitter that is designed to transmit a pilot tone in an ISM band.

Abstract: Methods related to delivery of various heart valve implants are described. The implant may be delivered using an ultrasound imaging delivery system. The ultrasound imaging delivery system may be used to deliver a variety of different devices, including mitral valve reshaping devices, mitral valve replacement valves, and others. A deployment catheter carrying an implant having a tissue anchor is advanced to a deployment site in a heart. An imaging element is positioned adjacent the implant and a relationship between the tissue anchor and an anatomical landmark in the heart is visualized. The implant is then attached by driving the tissue anchor into tissue in the heart.

Abstract: A shared resource medical system for monitoring a patient during emergency situations includes a portable defibrillator and an ultrasound transducer physically and communicatively coupled to the defibrillator. The defibrillator includes sensors, a display screen, a power supply, a data storage device, and a defibrillator processor operatively coupled to the screen, the power supply, and the storage device and configured to receive and process user input, receive patient physiological data from the sensors, and generate an interface on the display screen. The ultrasound transducer is configured to obtain ultrasound physiological data of the patient and send the ultrasound physiological data to the defibrillator processor.

Abstract: A cardiac health assessment system and method for use with a handheld electronic device. The cardiac health assessment system includes an electronic device case (EDC), a plurality of electrodes, and a circuit board. The EDC secures the handheld electronic device. The electrodes include a first ECG electrode, a second ECG electrode, and a third electrode. The first ECG electrode is placed on an outer surface of the EDC. The second ECG electrode and the third electrode are placed on each side of the EDC to facilitate a thumb and fingers of a user to be placed on the handheld electronic device. The electrodes capture data indicative of the cardiac health of the user. The circuit board includes a microphonic sensor, an Inertial Measurement Unit (IMU) sensor, and a microcontroller. The microphonic sensor and IMU sensor capture cardiac health data. The microcontroller transmits cardiac health data to the handheld electronic device.

Abstract: A smart watch described in this document includes hardware and software necessary to obtain motion and sensor data from a user wearing the smart watch. The described smart watch can continuously collect sensor data from the user and combine the sensor data from multiple sensors to enhance the accuracy of the sensor data analysis and provide relevant feedback information to the user. In addition, the described smart watch is capable of pairing with an external personal portable device, such as a smartphone or tablet to correlate the collected sensor data with activities performed by the user on the paired device. The smart device can also transmit data to a cloud server to collect sensor data and correlation analysis data for further analysis and provide statistical analysis of the collected sensor data and correlation analysis data.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for receiving user input, the user input indicating a user command to display a waveform strip screen, in response to the user input, processing patient-specific data to provide waveform data, and displaying the waveform strip screen on the mobile device, the waveform strip screen displaying one or more waveform strips, each waveform strip of the one or more waveform strips being based on the waveform data and graphically depicting a physical waveform strip.

Abstract: This document presents a system for managing treatment for an emergency cardiac event. The system includes memory, one or more electronic ports for receiving ECG signals, and a treatment module executable on one or more processing devices. The module is configured to perform a number of transformation on portions of an ECG signal into frequency domain data, obtain one or more previous values derived from one or more time segments of the ECG, and determine, based on the frequency domain data a first value and a second value, determine a probability of therapeutic success. The module is further configured to cause one or more output devices to present an indication of the probability of therapeutic success.

Abstract: The various embodiments of the present invention disclose a stand-alone, scalable cardiac health monitoring device for 1-6-12 lead ECG data acquisition and a method of working thereof. The method of monitoring cardiac health condition of a patient comprises of receiving, by a cardiac monitoring device, an electrocardiograph (ECG) input data signals from at least two electrodes attached to the patient, performing, a quality check on acquiring the ECG input data signals, processing the acquired ECG input data signals, encrypting the processed ECG input data signals and transmitting the encrypted ECG signals to one or more external user devices over a wireless communication interface. The acquiring the ECG input data signals comprises of integrating a closed loop Right Leg Drive (RLD) as a shield drive and a cable/electrode shield to reduce noise coupling to the ECG input data signals.

Abstract: Methods and systems treat abnormal cardiac electrical activity employing a probe having first and second ablation electrodes disposed on a distal portion of the probe and a sensing electrode disposed between the first and second ablation electrodes, bringing the probe into contact with cardiac tissue, and applying energy through the first and second ablation electrodes to ablate target tissue along an ablation path, monitoring cardiac electrical activity using the sensing electrode to detect the cardiac electrical activity. After making an observation that the cardiac electrical activity is no longer detectable by the sensing electrode, energy application is terminated.

Abstract: An endoscope includes a body and a circuit board mounted within the body. A cable couples the circuit board to an imaging system. A common-mode choke is mounted within the body and is configured to electrically isolate the cable from the body at cautery frequencies. A method includes twisting a plurality of wires together to form a twisted set of wires. The twisted set of wires is wound around a core so that windings do not overlap, and so that a first winding and a last winding are separated from each other. Wires in the twisted set of wires are coupled to a plurality of wires in the cable. Also, these wires in the twisted set of wires are also coupled to the circuit board.

Abstract: A system, computer-readable storage medium, and a method capable of, directly or indirectly, estimating sleep states of a user based on sensor data from movement sensors and/or optical sensors.

Abstract: In embodiments, a wearable cardioverter defibrillator (WCD) system is configured to be worn by an ambulatory patient. In the event that the WCD system determines that defibrillation is needed, it delivers a defibrillation shock. To diminish the possibility that the patient will be shocked due to a false positive detection, the WCD system alerts a patient that a defibrillation shock is imminent, and invites them to react to avert it. Alerting may be by a very weak shock, or jolt. Alerting by a jolt can be a last resort warning. An advantage can be that the patient has a higher chance of being alerted by the jolt, especially in the event that the patient is not reacting to other human-perceptible alerts, such as when the patient is riding a motorcycle.

Abstract: The invention relates to an implantable sensor for detecting an electrical excitation of muscle cells, in particular cardiac muscle cells, wherein it is provided that the sensor comprises a dielectric component and a contact point for contacting muscle cells, which is connected to the dielectric component, so that an electric field in the dielectric component, and correspondingly a capacitance of the dielectric component, change with an electrical excitation of the muscle cells. The invention furthermore relates to a system comprising a sensor and an implant.

Abstract: An automated evoked potential analysis apparatus for improved monitoring, detecting and identifying changes to a patient's physiological system is described. The apparatus includes an input device for obtaining electrical potential data from the patient's physiological system after application of stimulation to a patient's nerve and a computing system for receiving and analyzing the electrical potential data. The computing system includes a processing circuit configured to: generate a plurality of evoked potential waveforms (EPs) based on the electrical potential data, measure changes or trends in the generated EPs utilizing a sliding window of analysis, display incremental changes in waveforms between full subsets of EPs, and determine an alert vote for each subset, representative of changes to the physiological system generating the EPs.

Abstract: Systems, methods, and other techniques for estimating the level of an analyte present in a patient during a time interval using electrocardiogram (ECG) signals. The estimate can be improved using information about the patient's posture.

Abstract: Physiological variables, metrics, biomarkers, and other data points can be used, in connection with a non-invasive wearable device, to screen for, and predict, mental health issues and cognitive states. In addition to metrics such as heart rate, sleep data, activity level, gamification data, and the like, information such as text message and email data, as well as vocal data obtained through a phone and/or a microphone, may be analyzed, provided user authorization. Applying predictive modeling, one or more of the monitored metrics can be correlated with mental states and disorders. Identified patterns can be used to update the predictive models, such as via machine learning-trained models, as well as to update individual event predictions. Information about the mental state predictions, and updates thereto, can be surfaced to the user accordingly.

Abstract: At least one of at least one data-dependent scale factor or at least one data-dependent detection threshold is determined responsive to at least one block of time-series data of an auscultatory-sound signal generated by an auscultatory-sound sensor operatively coupled to a portion of the skin of a test-subject, wherein the at least one data-dependent scale factor or at least one data-dependent detection threshold provides a measure of a range of values of the at least one block of time-series data in relation to a predetermined metric, and is used to determine whether or not the auscultatory-sound sensor is either debonded or detached from the skin of the test-subject.

Abstract: Systems and methods for navigation and positioning a central venous catheter within a patient. The system may include a first pole and a second pole designed to generate an electric field sufficient to obtain a plurality of field measurements. The system may include a stylet inserted into a medical device. The stylet may include a magnetic assembly configured to produce a magnetic field positioned along a distal portion of the stylet, and a stylet electrode positioned distal of the magnetic assembly. The stylet electrode may be designed to function as both an interior excitation electrode and an interior detection electrode. Advancement of the medical device in the patient may include using a conductance curve generated from the plurality of field measurements to identify an obstruction or malposition in the patient.

Abstract: A patient worn sensor assembly for detecting, recording, and communicating patient vital signs can be integrated into a garment to be worn by the patient. A lead assembly can be integrated into a garment to connect electrodes in contact with the skin of a patient to a sensor assembly that collects vital sign information from the electrodes. The lead assembly can be multi-layered and can include, for example, two outer anti-static satin fabric layers as top and bottom layers, muslin fabric insulator layers adjacent to the anti-static satin fabric layers, shield layers that include muslin with silver fabric adjacent to the insulator layers, and an inner layer of fabric with conductive thread (or alternatively conductive thread not integrated with other fabrics, or a layer that is substantially composed of conductive thread).

Abstract: A clip configured to be coupled to an electrocardiogram sensor unit. The clip includes an electrically conductive material having a first surface and a second surface opposite the first surface. The clip also includes electrical insulation coupled to the second surface of the electrically conductive material, and an electrode defined by an exposed portion of the first surface of the electrically conductive material. The clip may be flexible or substantially rigid.

Abstract: Methods, systems, and apparatus for detecting and/or validating a detection of a state change by matching the shape of one or more of an cardiac data series, a heart rate variability data series, or at least a portion of a heart beat complex, derived from cardiac data, to an appropriate template.

Abstract: A biological signal detection apparatus includes a neck band worn by a user along a circumferential direction of a neck of the user and a pair of sensors mounted to both ends of the neck band to detect a biological signal. Each sensor includes a conductive cloth with a planar or substantially planar shape, a main body on which the conductive cloth is set, a frame body that holds a periphery of the conductive cloth between the main body and the frame body, and an input terminal provided on a surface of the main body that opposes the frame body.

Abstract: A system and method is presented for cuff-less blood pressure measurement in a mobile device. A key aspect of this disclosure is the discovery of a new location for blood pressure measurement at the fingertip of a subject and that reflectance-mode photoplethysmography can be used to help make this measurement. Through experiments in human subjects, it was discovered that it is indeed possible to measure systemic blood pressure by having a subject press the fingertip against a reflectance-mode photo-plethysmography-force sensor unit under visual guidance and then compute blood pressure from the resulting variable-amplitude blood volume oscillations and applied pressure via an oscillometric algorithm.

Abstract: Systems and methods for automatically analyzing and selecting prominent channels from multi-dimensional biomedical signals in order to detect particular diseases or ailments are provided. Such systems and methods may be applied in different ways to obtain numerous benefits, such as lowering of power and processing requirements, reducing an amount of data acquired, simplifying hardware deployment, detecting non-trivial patterns, obtaining, clinical episode prognosis, improving patient care, and/or the like.

Abstract: A method including calculating, at multiple intra-cardiac locations, respective average atrial fibrillation cycle-length (AFCL) values. A determination is made as to whether the calculated average AFCL values are indicative of a regular atrial fibrillation (AF) activity. Gradients between pairs of the average AFCL values are calculated for a plurality of average AFCL values that are determined to be indicative of regular AF activity. The calculated AFCL gradients are presented to a user, overlaid on a map of at least a portion of the heart.

Abstract: One variation of a method for testing contact quality of electrical-biosignal electrodes includes: outputting a drive signal through a driven electrode, the drive signal comprising an alternating-current component oscillating at a reference frequency and a direct-current component; reading a set of sense signals from a set of sense electrodes at a first time; calculating a first combination of the set of sense signals; calculating a first direct-current value comprising a combination of the first combination and the direct-current component of the drive signal at approximately the first time; and at a second time succeeding the first time, shifting the direct-current component of the drive signal output by the driven electrode to the first direct-current value.

Abstract: Sensing devices including flexible and stretchable pressure sensors may be associated with or incorporated in garments intended to be worn against a body surface (directly or indirectly), or may be associated with other types of flexible substrates. Systems and methods for storing, communicating, processing, analyzing and displaying data collected by sensor components for remote monitoring of conditions at or near body surfaces are also disclosed. Sensors and sensor systems provide substantially real-time feedback relating to current body conditions and may provide user-specific feedback relating to gait and footwear fit and performance, facilitating improved footwear matching to individual users and improved footwear design and manufacturing, and enabling early intervention when conditions indicate intervention is appropriate.

Abstract: A method, including receiving sets of signals during multiple cardiac cycles, each set indicating, for a probe inserted into a cardiac chamber, a 3D location of a distal end of the probe, electrical potentials measured at the location, and respective times during a given cycle when the potentials were measured. The received measurements and the respective times are compared to a first template for a sinus rhythm cycle and a second template for a non-sinus rhythm cycle so as to identify a sequence of cycles including consecutive first, second, and third cycles wherein the first and second cycles match the first template and the third cycle matches the second template. A physical map is generated based on the locations. Based on the received locations and corresponding potentials, an electroanatomic map including the local activation times for the non-sinus rhythm cycle overlaid on the physical map is rendered to a display.

Abstract: The exemplified methods and systems described herein facilitate the quantification and/or removal of asynchronous noise, such as muscle artifact noise contamination, to more accurately assess complex nonlinear variabilities in quasi-periodic biophysical-signal systems such as those in acquired cardiac signals, brain signals, etc.

Abstract: Methods and devices for improving pelvic floor dysfunction in a patient suffering therefrom by electrically modulating neural tissue in a minimally invasive fashion using an electrical micro stimulator are provided.

Abstract: A method of analyzing a complex rhythm disorder in a human heart includes accessing signals from a plurality of sensors disposed spatially in relation to the heart, where the signals are associated with activations of the heart, and identifying a region of the heart having an activation trail that is rotational or radially emanating, where the activation trail is indicative of the complex rhythm disorder and is based on activation times associated with the activations of the heart.

Abstract: Provided are a means to detect a plurality of dynamics, a processing unit that calculates a temporal change in the detected dynamics, and an evaluation device that determines exacerbation of clinical conditions in heart failure of a patient based on the calculated change in the patient's dynamics over time. The present invention makes it possible to detect, early and with high accuracy, that the onset of acute heart failure is imminent.

Abstract: The invention provides a neck-worn sensor (referred to herein as the ‘necklace’) that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the necklace can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.

Abstract: Electrical impulses are received from a beating heart. The electrical impulses are converted to an ECG waveform. The ECG waveform is converted to a frequency domain waveform, which, in turn, is separated into two or more different frequency domain waveforms, which, in turn, are converted into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms. The plurality of subwaveforms and discontinuity points are compared to a database of subwaveforms and discontinuity points for normal and abnormal patients or to a set of rules developed from the database. An ST segment and one or more ST subwaveforms within the ST segment are identified from the plurality of subwaveforms and discontinuity points based on the comparison. The ECG waveform with the one or more ST subwaveforms within the ST segment is displayed.

Abstract: In an example, an n-dimensional method of fundamental solution (MFS) is used to compute reconstructed electrical activity on a cardiac envelope based on geometry data and electrical data, where n is a positive integer greater than three. The electrical data represents electrical activity measured non-invasively from a plurality of locations distributed on a body surface of a patient, and the geometry data represents three-dimensional body surface geometry for the locations distributed on the body surface where the electrical activity is measured and three-dimensional heart geometry for the cardiac envelope.

Abstract: Techniques for classifying cardiac events in electrocardiogram (ECG) data. A feature set is generated by analyzing ECG data for a patient using a first phase in a machine learning architecture. A first cardiac event in the ECG data is classified based on the feature set, using the first phase in the machine learning architecture. A second cardiac event in the ECG data is classified based on the classified first cardiac event and the feature set, using a second phase in the machine learning architecture. The second cardiac event overlaps at least partially in time with the first cardiac event. Further, a plurality of feature sets, corresponding to a plurality channels of ECG data, are generated using paths in a machine learning architecture. A cardiac event in the ECG data is classified using the machine learning architecture based on the plurality of feature sets.

Abstract: A switchable filter device for use in a system for recording electro-physiological signals. The filter device includes a plurality of recording channels, the recording channels having an ablation recording channel. Each recording channel has a patient side terminal at a patient interface and a corresponding recording side terminal at a recording device interface. Each recording channel includes a first signal path with a first frequency dependent transmission characteristic having a first pass band, a second signal path with a second frequency dependent transmission characteristic different from the first frequency dependent transmission characteristic, the second frequency dependent transmission characteristic having a second pass band overlapping the first pass band, and switching devices operable to switch between the first signal path and the second signal path in response to a control signal indicative of a transient interference signal.

Abstract: A wearable apparatus and a method for ECG signal collection includes: a main body, including a first ECG sensor electrode provided on a side of the main body away from a wearing position of an individual and a second ECG sensor electrode provided on a side of the main body close to the wearing position, a securing portion, including a third ECG sensor electrode provided on a side of the securing portion away from the wearing position, and an ECG sensor, provided in the main body and configured to: electrically connect to the first ECG sensor electrode and the second ECG sensor electrode, electrically connect to the third ECG sensor electrode through a wire in the securing portion, and collect ECG signals from close circuits formed by the first ECG sensor electrode, the second ECG sensor electrode, and the third ECG sensor electrode.

Abstract: Disclosed is a vital sign monitoring system. The system comprises a segmented electrode forming an in-plane electrode array, wherein the electrode comprise a skin contacting skin adhering contact layer mounted on an electrode backing material, a deformation sensor arranged for identifying deformation information of the electrode, a signal processor arranged to receive a vital sign signal from the electrode and process the deformation information to remove artefacts from the vital sign signal, wherein the electrode comprises multiple electrode segments and wherein the signal processor is arranged to select that electrode segment that has a lowest deformation of all electrode segments of the electrode.

Abstract: Implantable and wearable devices and system for transmitting signals ultrasonically through biological tissue are implemented based on an Internet of Medical Things (IoMT) platform software and hardware architecture. The devices are size-, energy-, and resource-constrained and implement ultrasonic communication protocols and communicate with each other through ultrasound.

Abstract: The present system allows for the physician to change the relative height of the signal to allow for examination of details of the signals, while maintaining an ability to interpret signal voltage levels absolutely based on color or other secondary mechanism beyond signal height. The disclosed system and method provide for faster and more accurate analysis based upon the color of the signal. The signal height may change, such as to view, display, or examine details of the signal, while the colors of the display do not. The color scale of the signal provides an absolute scaling of the signal regardless of the displayed height.

Abstract: A device includes a tissue conduction communication (TCC) transmitter that generates a TCC signal including a carrier signal having a peak-to-peak amplitude and a carrier frequency cycle length including a first polarity pulse for a first half of the carrier frequency cycle length and a second polarity pulse opposite the first polarity pulse for a second half of the carrier frequency cycle length. Each of the first polarity pulse and the second polarity pulse inject a half cycle charge into a TCC pathway. The TCC transmitter starts transmitting the TCC signal with a starting pulse having a net charge that is half of the half cycle charge and transmits alternating polarity pulses of the carrier signal consecutively following the starting pulse.

Abstract: Disclosed are systems for non-invasively determining a measurement of an analyte. The systems include an electrocardiogram sensor and a processing device operatively coupled to the electrocardiogram sensor. The processing device can execute instructions to receive electrocardiogram data from the electrocardiogram sensor and apply a machine learning model, wherein the machine learning model has been trained based on previous electrocardiogram data associated with a subject and source of an analyte measurement associated with the subject. The system may also determine an indication of a level of the analyte based on the electrocardiogram data.

Abstract: An arrhythmia monitoring device includes a plurality of pairs of ECG sensing electrodes disposed in a garment configured to be worn about a torso of a patient, and signal acquisition circuit configured to be electrically coupled to the plurality pairs of ECG sensing electrodes. The device includes a processor in communication with the signal acquisition circuit configured to execute a selection process comprising identifying a quality of each of a plurality of ECG signals, ranking the signals based on the identified quality, and selecting at least two ECG signals to monitor having highest quality. The processor is configured to re-execute the selection process following an event including at least one of the garment shifting on the torso, the garment being repositioned on the torso, and the garment being removed and returned to the torso of the patient, and monitor the selected at least two ECG signals for a cardiac arrhythmia.

Abstract: In various embodiments, a first classification assigned to a periodic component of an electrical waveform that represents electrical activity in a patient's heart may be identified (302). A corresponding periodic component of a hemodynamic waveform that represents hemodynamic activity in the patient's cardiovascular system may be analyzed (306, 318, 328). The corresponding periodic component may be causally related to the periodic component of the electrical waveform. Based on the analysis, the previously-assigned classification may be assigned (312, 324) to the corresponding periodic component of the hemodynamic waveform in response to a determination, based on the analyzing, that the previously-assigned classification also applies to the corresponding periodic component.

Abstract: Disclosed systems include mobile ECG sensors, systems and methods. Some embodiments provide ECG sensors in a credit card form factor that allows a user to contact two electrically isolated electrodes to measure heart electrical signals for a Lead 1 ECG.

Abstract: A swing analysis system is disclosed herein. The swing analysis system includes a force measurement assembly configured to receive a user; and a data processing device operatively coupled to the force measurement assembly, the data processing device is configured to receive one or more signals that are representative of forces and/or moments being applied to a top surface of the force measurement assembly by the user, and to convert the one or more signals into output forces and/or moments, the data processing device is further configured to determine one or more swing performance metrics for the user using the output forces and/or moments from the force measurement assembly.