Abstract: An administering apparatus for delivering a dosage of product including a casing with a reservoir for the product, a piston within the reservoir to deliver the product, a piston rod for engaging the piston, a drive device for driving the piston rod, and a dosage setting member mechanically engaging the piston rod and a stopper for the dosage setting member. The casing includes a front casing section containing a reservoir for the product and a rear casing section detachably connected to the front casing section. The front casing section is connected to or forms a first latching element, and the rear casing section is connected to or forms a second latching element. The latching elements are in latching engagement when the casing sections are connected. The casing sections may be axially fixed to one another by the latching engagement.

Abstract: A front-loading syringe, which comprises a movable plunger for injecting liquid contrast media, is mountable on a front wall of an injector housing having a pressure jacket, by a first quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An injection end of the syringe may include loop-shaped reinforcing handle portions.

Abstract: A safety syringe comprises a needle set, a barrel and a plunger. Wherein the front end of the needle set is connected with a needle, while the rear end is provided with a first coupling portion; the bottom of the needle set has on the periphery thereof at least an annular flange. The barrel is hollow, its front end is formed as a socket to connect the needle set; the socket has on its inner wall two mutually neighboring annular flanges. The rear end of the barrel is used for slipping in the plunger of which the front end has a piston; a second coupling portion is provided on the front end of the piston. Hence when the needle set is connected to the needle-set socket, the said at least an annular flange on the periphery of the needle set is located between the two annular flanges on the inner wall of the needle-set socket to increase the tightness of connection.

Abstract: A system is provided which permits syringe barrels of prefilled disposable syringes to be filled and capped on standard vial filling equipment, and which permits the syringe body and piston comprising the barrel to be simultaneously sterilized by a sterilizing gas. The system provides means for stabilizing syringe barrels so they can be conveyed upright on their bases without tipping through vial filling and capping equipment. Preferably, the stabilizing means comprises a cylindrical sleeve into which the lower end of the syringe body is inserted, thereby stably supporting it against tipping. The system also provides means by which the piston is retained in close proximity to the lower end of the syringe body, but slightly separated therefrom to permit access to all surfaces of the piston by a sterilizing gas.

Abstract: A spray or delivery device is arranged to dispense a dye into the anterior chamber of a human eye or other mammalian eye for the purpose of staining a specific ocular structure or tissue. An ocular structure of particular interest is the anterior lens capsule. The spray device includes a cannula having a distal end arranged for insertion into the anterior chamber of the eye. The cannula preferably has a dispensing orifice located at a side of the cannula offset from the distal end. The orifice preferably dispenses the fluid dye or stain in spray form. In one exemplary embodiment, the cannula has a fin extending radially outward from the cannula. In another exemplary embodiment, the cannula has a flared sleeve surrounding and extending from the orifice. In a method for conducting intra-ocular surgery, said delivery device would dispense a dye in a particular fashion so as to control its application to the intended target tissue, thereby limiting delivery of the dye to undesired surrounding tissue structures.

Abstract: An improved pump, reservoir and reservoir piston are provided for controlled delivery of fluids. A motor is operably coupled to a drive member, such as a drive screw, which is adapted to advance a plunger slide in response to operation of the motor. The plunger slide is removably coupled to the piston. The piston comprises a first member and a second member. The first member has an external proximate side and an external distal side. The external proximate side is adapted to contact the fluid and is made of a material having a first stiffness. The second member has a first side and a second side and is at least partially disposed within the first member. The first side of the second member is adjacent to the external proximate side of the first member and is made of a material having a stiffness which is greater than the first stiffness.

Abstract: The invention relates to compositions, methods, apparatus, and kits for alleviating or preventing vasoconstriction or vasospasm in a mammal. The compositions, methods, apparatus, and kits are also useful for alleviating or preventing ischemic tissue damage resulting from ischemia associated with cerebral vasoconstriction which follows aneurysmal subarachnoid hemorrhage, with embolic stroke, with coronary artery obstruction, and with other conditions. These compositions, methods, apparatus, and kits generally relate to adventitial (i.e., extra-luminal) administration of a nitric oxide donor compound to a blood vessel in a mammal.

Abstract: A dose setting device for a delivery system has a piston rod (6, 9) which successively presses a piston (2) into a cylinder ampoule (1). Doses are set by rotating a second part (9) of the piston rod (6, 9) in relation to a first part (6). The two parts are connected by mating threads so that the total length of the piston rod (6, 9) is increased proportional to the angle of rotation, and a point (18) on the second part is moved away from a stop position fixed in relation to a housing (5) The set dose is delivered when the point (18) is moved back to the stop position. The first part (6) can be axially displaced but not rotated in the housing (5), and the second part (9) can both rotate and be axially displaced. The first part (6) is maintained in abutment with the piston (2) and the second part (9) is coupled to be rotated by a dose setting wheel (20).

Abstract: Disclosed herein is a safety syringe. According to the safety syringe of the present invention, an adapter connected to an injection needle is threadedly coupled with the neck of a cylinder while interposing an O-ring therebetween. Thus, the movement of the injection needle is effectively prevented while in use, and thus the injection needle can be pricked accurately at a desired position of the patient's body. Since the adapter is formed with grooves, whereas a plunger is formed with two protrusions positioned diametrically opposite to each other so as to be inserted into the grooves, the adapter is rotated and then moved downwardly in accordance with the successive rotation and downward movements of the plunger after the adapter is released from the neck of the cylinder. The plunger is formed at its upper surface with a vertical rod extending upwardly from an eccentric position, whereas the adapter is defined with a conical cavity.

Abstract: A single use syringe and a plunger rod locking device for such a syringe are provided. The locking device and plunger rod include features that cause the plunger rod to be locked with respect to the syringe barrel upon completion of an injection stroke. A cutting member is provided at the distal end of the locking device. The cutting member will penetrate, and thereby disable the stopper affixed to the plunger rod in an attempt to retract the plunger rod following the injection stroke. The locking device includes barbs for engaging the syringe barrel.

Abstract: A single-use syringe comprises a barrel having a proximal end, a distal end and an inside surface, and a plunger rod having a proximal portion and a distal portion connected by a disengageable connection. The plunger rod further includes a stopper on its distal end. The disengageable connection is strong enough to hold the proximal and distal portions together during normal use of the syringe and disengageable upon application of an additional force applied to the proximal portion. A catch on the proximal portion of the plunger rod and a discontinuity in the chamber engage to prevent removal of the proximal portion from the barrel.

Abstract: The invention refers to a syringe of single-use type intended for injection or lab tests with an injection needle slidable into the syringe after usage. The intention with this is to eliminate the risk for prick injuries when the syringe is handled after usage. A design of a single-use syringe such that the needle becomes kept in the interior of the syringe after usage has proved to be involved by different kinds of complications and has made the syringe complicated and expensive to manufacture. An uncomplicated and reliable syringe of the kind stated in the introduction is achieved according to the invention by the fact that the plunger (2) of the syringe is provided with a coupling device (12) designed such that in the completely pushed in position of the plunger the rear part of the injection needle (6) is coupled to the plunger (2) and follows the plunger when the plunger is withdrawn.

Abstract: Adapters for use with an angiographic injector. A face plate adapter includes a channel for receiving a rearward end of a syringe. First and second mounting flanges on the adapter overlay a portion of the channel, to cooperate with mounting flanges on a rearward end of the syringe, so that the syringe mounting flanges may be inserted between the adapter mounting flanges, and then rotated in the channel behind the adapter mounting flanges, to thereby lock the syringe to the adapter. The adapter further includes one or more locking pins, which in a locked position extend across the channel, to block the syringe from rotating in the channel and thereby prevent a syringe from being dismounted from the adapter. A collar incorporated in the adapter interacts with a drive ram of the injector to move the locking pins into their locked position whenever the ram is forward of a rearwardmost position.

Abstract: A hypodermic syringe includes a barrel with a plunger slidably extending therein. The barrel may include a barrel adapter at one end to define a luer hub socket and the outer walls of slots in the barrel. The plunger includes an outer plunger element and an inner plunger element telescoping together with a bungee resisting extension of the assembly. The inner and outer plunger elements may be locked in the extended position with the bungee in tension. A seal stop is located at the seal end of the plunger to define an annular pinch therewith to hold an annular seal in radial extension sealing against the internal sidewall of the barrel. A luer hub is fixed at the needle end of the barrel. A plunger cap may be advanced after injection to rotate the plunger. A resistance lock retains the cap and plunger indexed until actuation.

Abstract: A injection system having a syringe body which defines a pumping chamber. A syringe plunger is located in the pumping chamber and is adapted for reciprocal motion within the pumping chamber. The syringe plunger includes a capture member projecting outwardly in a proximal direction. An actuating shaft is coupled to the syringe plunger and is movable through the syringe body to control movement of the syringe plunger. The capture member is adapted to flex radially outwardly when contacted by the actuating shaft to form a releasable engagement with the actuating shaft when the actuating shaft and the capture member are in an engagement position. A release actuator is disposed proximal to the syringe body, and the capture member releases the actuating shaft upon engagement with the release actuator.

Abstract: An automatically retractable safety syringe includes a needle assembly consisting of a cannula, a needle hub and a rubber O-ring, a needle cap, a retracting spring, a breakable and retractable plunger, a plunger gasket and a medicine barrel; in accordance with the structure of the said automatically retractable safety syringe of the present invention, since the breakable plunger is assembled inside the medicine barrel, after being pushed all the way to the end, it is forced to break automatically into two parts for reducing it's length so as to provide enough space for the retracting spring to drive the needle assembly moving along the sliding passages for accomplishing an automatically retracting action.

Abstract: A syringe assembly comprises a syringe barrel having an elongated body defining a chamber for retaining fluid, an open proximal end, a distal end and a frusto-conically shaped tip extending from the distal end and having a passageway therethrough in fluid communication with the chamber. The chamber has an inside diameter of at least 13.5 mm. A stopper is in fluid-tight engagement inside the barrel. An elongated plunger rod extends proximally from the stopper through the open proximal end of the barrel. A flange is positioned at the proximal end of the plunger rod. The flange is shaped and positioned to limit the distal motion of the plunger rod in the barrel by contacting the proximal end of the barrel. A tip cap is releasably connected to the tip for sealing the passageway and the chamber contains injectable liquid.

Abstract: An intradermal delivery device for use in intradermally injecting substances into the skin of an animal includes a needle cannula supported by a hub portion that is attachable to a prefillable container. A limiter portion surrounds the needle cannula and extends away from the hub portion toward a forward tip of the needle cannula. The limiter portion includes a skin engaging surface extending in a plane generally perpendicular to an axis of the needle cannula. The skin engaging surface is received against skin of an animal to administer an intradermal injection. The forward tip extends beyond the skin engaging surface a distance that enables penetration of the needle cannula into the dermis layer of the skin of the animal enabling injection of the substance into the dermis layer of the animal. The device includes enclosure means that is moveable for concealing the needle cannula after the injection has been administered.

Abstract: Disclosed herein is a syringe for collecting blood. The syringe is designed to suck blood into a cylinder through a needle which is inserted into a blood vessel, by drawing a piston using a piston rod. In this case, two guide slits are formed on a rear portion of the cylinder in such a way as to be symmetrical with respect to a midpoint therebetween. A rod-shaped handle is provided at a rear end of the piston rod so that the handle is transversely fitted into the guide slits. Thereby, when a user puts his/her thumb on a rear end of the cylinder and rearwardly draws the handle along the guide slits using his/her index and middle fingers, blood is sucked into the cylinder by a rearward movement of the piston in the cylinder.

Abstract: A syringe of improved ergonomics having an ellipsoidal barrel which contains an ellipsoidal plunger. The plunger consists of: a plunger tip of a rigid, non-elastomeric material which interfaces a medical fluid contained in the syringe barrel; and an elastomeric ring which slideably interfaces the inside wall of the syringe barrel. In one embodiment the plunger contains a plastic plunger insert which supports the elastomeric ring, the interior of which is provided with an ellipsoidal cavity. A self-aligning plunger rod having a ball portion on its distal end is inserted into the cavity of the plunger insert. The ball portion freely moves in the cavity and directs the external force exerted on the plunger rod in an axial direction.

Abstract: A multi-compartment syringe for storing two or more substances in separate compartments comprises a tubular body having an opening at each end and a plunger. The body has two or more compartments defined along its length, where each compartment has a successively larger diameter. The plunger has a plunger head at one end that partitions the first and second compartments and one or more bungs, slidable along the plunger's shaft, for partitioning each of the other compartments. The plunger head and the bungs can be unsealed to establish a flow communication between the compartments.

Abstract: A disposable syringe includes a tubular barrier member retained in a rear passageway of a barrel. A tubular needle seat for fixing a needle cannula is retained on the barrier member, and abuts against an abutment wall in the front passageway of the barrel while the needle cannula is disposed outwardly of the barrel. A plunger is slidable in the rear passageway, and has a seal member to seal a cavity confined in a plunger body and containing a fluid at a reduced pressure. When a pushing force applied to the plunger body moves the barrier member against the first and second frictional forces, the needle seat is released, and the seal member is ruptured, so that the needle seat and the needle cannula are suctioned into the cavity due to the pressure difference between the ambient atmosphere and the reduced pressure.

Abstract: The retractable safety syringe for drawing back a soft piston therein is comprised of a needle set, a cylindrical barrel and a plunger. A retractable mechanism is provided for pulling the needle set into it. The plunger is provided on the front end thereof with a soft piston, and with an activating piece to activate the retractable mechanism or with a connecting piece connectable to the retractable mechanism. When in assembling, the soft piston of a plunger is pushed to the top point of a space provided for injection, before deformation of the piston, an activating piece or a connecting piece on the plunger does not activate or connect with the retractable mechanism, and when the plunger is pushed by a force larger than a preset amount, the piston is compressed to deform and to render the activating piece to activate or connect with the retractable mechanism to pull the needle set into the cylindrical barrel automatically or manually.

Abstract: A bypass type prefilled syringe has a tubular body formed with a bypass for establishing communication between front and rear compartments for preliminarily storing medicament and pharmaceutical liquid, respectively. A gasket for dividing interior space of the tubular body into the front and rear compartments includes a plurality of circumferential ribs . A plurality of annular recesses are each formed between neighboring ones of the circumferential ribs. First and second axial slots are formed on the circumferential ribs so as to define a bent outflow path for the pharmaceutical liquid at the time of communication between the front and rear compartments via the bypass.

Abstract: A safety syringe comprises a barrel having a projection in a rear end thereof, a needle holder for mount of a needle, the needle holder having a dragged portion, a stopper movable in the barrel, the stopper having a drag portion adapted for engaging into the dragged portion of the needle holder and a plunger connector, a plunger for moving the stopper in the barrel having a stopper connector engaged with the plunger connector of the stopper. When pulled backwards to the end after injection, the plunger connector of the stopper is forced onto the projection of the barrel and disengaged from the plunger, enabling the plunger to be removed from said barrel.

Abstract: Cannulas are provided for delivering therapeutic material to a treatment site. The cannula includes a cannula body with a plurality of openings at the distal end, including a longitudinal opening and a plurality of transverse openings that are axially spaced from each other. The cannula also includes a plunger that is configured to be slidably disposed within the cannula lumen. When the plunger is proximally displaced in the cannula lumen, the plunger seals the distal end and deflects the therapeutic material out the transverse openings. As the plunger is proximally displaced within the lumen, the therapeutic material is forced to perfuse out transverse openings located proximal of the plunger position. In one embodiment, the plunger includes an additional pliable sealable member. In another embodiment, the distal end of the cannula body may be implanted by separating the distal end from the cannula body.

Abstract: The invention relates to a continuous liquid infusion device which can be easily prepared for operation with small force, and can infuse liquid at constant infusion rate and amount over a long time. It comprises a liquid syringe section and a driving pump section mounted on the liquid syringe section, wherein sliding the pressing arm of the driving pump section upward leads to axially slides the piston in the negative pressure chamber to produce a negative pressure therein; and using returning force of the piston under the negative pressure, the liquid pushout plunger barrel is biased toward the upper edge of a pressing member through a locking member engaged with the piston so as to push out liquid in the liquid syringe from the liquid infusion port. Further, only the liquid syringe is disposable while the vacuum pump barrel on the driving side is good for repeated use (reusable).

Abstract: A syringe and its method of use, comprising two bodies; the first body or cylinder provided with a support surface at its end, and a second body or rod with pusher elements, which is introduced in the prior cylinder. The syringe can be used by means of a single hand and it is possible to perform the two actions of a syringe, sucking and injection, by changing the position of the fingers.

Abstract: A syringe and adapter combination allowing the syringe to be filled with fluid by the employment of one hand of an operator.

Abstract: A single-use system for separating blood and producing platelet concentrates includes an elongated container for receiving blood from a patient. The container has a movable plunger mounted within the blood container for expressing blood fractions separated during centrifugation of the container through a first port mounted at one end of said container, a second port mounted on the plunger, and a third port mounted on a plunger rod attached to the plunger.

Abstract: A syringe comprising a barrel and a plunger rod having a proximal portion and a distal portion is provided. The distal portion includes a stopper slidably positioned in fluid-tight engagement with the inside surface of the barrel. The structure is provided for holding the proximal portion and the distal portion together during normal use of the syringe and breakable upon application of an additional force applied to the proximal portion. Structure is also provided for preventing the proximal portion from applying distally directed force to the distal portion after the breakable connection is broken.

Abstract: A syringe for use with an injector includes a body comprising a distal discharge end, a plunger movably disposed within the body, and an agitation element disposed within the body between the plunger and the distal discharge end. The agitation element is acted on by a magnetic field to agitate the contents of the syringe. The magnetic field is generated by a source operably associated with the syringe or the injector. Preferably, the syringe contains an ultrasound contrast agent that is agitated by the agitation element. An injector system and a method for agitating the contents of a syringe are also provided.

Abstract: A dual-chamber syringe has a plunger within an inner delivery chamber in fluid communication with an ejection port. The deliver chamber is formed within a tubular element axially slidable within a tubular guide. The tubular guide and the syringe outer barrel form an outer reservoir chamber. The outer reservoir chamber is sealed from the delivery chamber while the tubular element is in a first position within the guide. Upon withdrawal of the plunger, frictional contact imparted by the plunger seal causes the tubular element to slide away from sealing engagement with the barrel into a second position within the guide. In the second position of the tubular element, a fluid passageway is opened from the reservoir to the delivery chamber allowing fluid to be drawn into the delivery chamber. A porous seal between the plunger rod and barrel allows air into the reservoir during transfer of fluid to the delivery chamber.

Abstract: The invention refers to a device for administering an injectable product in doses, comprising a casing, itself comprising: a reservoir for the product; a piston which forces product out of the reservoir when moved in a feed direction towards a reservoir outlet; a drive member (6); a driven member which is slaved by the drive member (6) when the drive member (6) is moved in the feed direction, so moving the piston in the feed direction; and a dosing member (15) which may be rotated about the sliding axis (V) of the drive member (6), to set the product dosage to be administered. The drive member (6) and the dosing member (15) abut each other via at least one dosage stopper (14, 18) each, one of which is provided on the drive member (6) and the other on the dosing member (15). At least one of these dosage stoppers (14, 18) at least partially encircles the sliding axis (V) of the drive member (6) in the form of a spiral.

Abstract: An injector device for delivery of liquid from a high pressure, the device comprising a housing, a pressure chamber 2 comprising a pressure barrel 4 for accommodation of at least one piston therein and having a front end opening 6 for ejection of the liquid, the pressure chamber being of sufficient strength to sustain the liquid pressure. The device further comprises a storage chamber 16, separate from the pressure chamber, for the liquid or the liquid precursor components, and a conduit 22 between the pressure chamber and the storage chamber. A pressurizing mechanism 26 in the housing is arranged to apply force, directly or indirectly, on the piston in the pressure barrel to create said liquid pressure.

Abstract: The present invention is an adjustable re-usable syringe actuator that delivers liquid at a substantially constant rate that is unaffected by a change in the viscosity of the liquid being pumped. The disposable syringe actuator is well suited for the infusion of small to medium volumes of liquid medication at low flow-rates. A preferred embodiment includes a purely mechanical device with no need for electricity, thereby providing a high level of patient mobility. The spring-powered device uses a variable length elongated flow regulation passageway to regulate the rate at which the spring depresses the syringe plunger. Thus, the rate of medication infusion is regulated by varying the length of the flow regulation passageway.

Abstract: A device for the treatment of periodontal disease includes a handle that has a configuration familiar to dental professionals, and a cartridge, that is locked into the handle when use, typically delivery of a composition to a periodontal pocket is desired. The cartridge provides for effective delivery of compositions, such as agents, as its tip is deformable, typically from a circular to an oval shape so as to flatten. The deformation may be made, either manually, by the dental professional, or upon contact with teeth or other tissues, whereby this flattened tip can penetrate deeply into periodontal pockets for quick and direct application of the composition, for example, therapeutic agents.

Abstract: There is provided a capsule for dental restoration material, which can administer to a site to be restored of a patient with a mixture in a good state where air bubbles are not substantially contained, immediately after mixing. In the capsule for dental restoration material for directly administering to a restoration site of a tooth with the mixture prepared by subjecting a dental restoration material comprising two components of definite amounts of previously weighed powder component and liquid component accommodated in a cylindrical mixing compartment in an isolated state from each other to making the liquid component flow into the mixing compartment and mixing the both components, an air-permeable filter that does not pass the powder component therethrough but can ventilate air within the mixing compartment into the outside of the mixing compartment is placed in at least a part of a peripheral wall of the mixing compartment.

Abstract: A syringe is provided that includes a barrel including a nozzle having an interior opening. A plunger rod of the syringe has a first end and a second end. The second end includes an extension dimensioned to ensure that a member, disposed with the second end and enclosing the extension, abuts the interior opening. The barrel may include a distal wall that supports the nozzle and the plunger rod may include a correspondingly configured distal face. The extension may include a longitudinal length such that upon engagement of the member with the interior opening, the length of the extension prevents compressive deformation of the member between the distal wall and the distal face. The member can have a transverse wall and a cylindrical sidewall extending along the second end of the plunger rod. The transverse wall may have a substantially uniform thickness. The extension defines a distal portion which may be dimensioned for selective engagement of the member with the interior opening.

Abstract: A disposable, single use syringe comprised of a hollow body, a retractable needle assembly positioned in the hollow body, and a plunger assembly in the hollow body. The plunger assembly includes an elongated frame portion including at least one guide track between its ends. A retraction member is releasably secured to one end of the frame and a catch member, including a catch element, is positioned with a guide configured to travel in the plunger frame guide track. An elastic member extends between the retraction member and the catch member. A retention assembly depends from the opposite end of the plunger frame and is configured to receive and secure the catch element and thereby tension the elastic member. The needle assembly and the retraction member have complimentary mating members, whereby the tension on the elastic member is released and the injection means is drawn into the hollow body after the needle assembly and the retraction member mate. A method of manufacture is also provided.

Abstract: The present invention provides an injection device and an actuator for an injection device, wherein the actuator comprises a generally rod-shaped driven member having a structured surface portion, a counter component having a structured surface portion engaging the structured surface portion of the driven member, whereby the driven member is movable by the counter component, and a spreader bushing for spreading open the counter component by a movement relative to the counter component, thereby allowing the driven member to shift freely, wherein the spreader bushing is selectively movable with and relative to the counter component.

Abstract: A syringe for use with an infusion pump, the infusion pump having a cavity for receiving the syringe. The syringe includes a syringe body, a plunger and an end cap. The syringe body has a tube that is open at a first end and transitions to a passage at a second end and a connector extending from the passage, the connector for attachment to an infusion set or tubing. The plunger is slidably mounted inside the tube and comprises a plunger tip and a plunger rod. The plunger tip has a front face that is complementarily received by the second end of the tube and a rear face, the plunger tip forming an interference fit with the tube. The plunger rod has a first end attached to the plunger tip and a second end extending outside the first end of the tube. The plunger rod has a cross-sectional shape that is complementarily received by the cavity of the infusion pump when inserted in only one direction.

Abstract: The present invention relates to a device for guiding a rod-shaped output member of an injection device with an exchangeable cartridge containing injection liquid, where the rod-shaped output member can be driven by defined distances in a direction reducing the volume of the cartridge in order to dispense the injection liquid, a clamp element being provided which can be secured releasably on the rod-shaped output member, which clamp element, in the clamped state of the rod-shaped output member, is movable in order to set the dose to be injected or to dispense the dose, and which clamp element is automatically released upon release and removal of the cartridge.

Abstract: This invention relates to a drug cartridge assembly for use with a reusable body assembly of a medication delivery pen. The drug cartridge is disposable and is in the form of a single integral unit having a generally tubular barrel. Medication is pre-filled into the drug cartridge and is retained therein by an elastomeric stopper or plunger. The plunger is in sliding fluid-tight engagement with a tubular wall of the barrel. A proximal end of the tubular barrel is configured for interconnecting the drug cartridge with a pen body assembly and a distal end of the tubular barrel is configured to securely but releasably engage a needle cannula assembly.

Abstract: A medication injection or delivery system is provided for injecting fluids such as insulin within body tissue. The device includes a housing, a flexible shaft movably mounted within the housing, and a dose setting mechanism for controlling the movement of the shaft with respect to a fluid-containing cartridge removably positioned within or mounted to the housing. The flexible shaft, according to exemplary embodiments, includes a plunger and a flexible cable connected to the dose setting mechanism. The plunger and dose setting mechanism are connected together by the flexible shaft. The dose setting mechanism, in one aspect of the invention, includes a screw, a locking mechanism, and a nut assembly connected to the flexible shaft. The dose setting mechanism is used to set the dosage and prime the catheter. The plunger retracts into a recess to permit a new cartridge to be installed quickly.

Abstract: A filler instrument comprises a first chamber section having a first cross sectional area and a second chamber section having a second cross sectional area less than the first cross sectional area. The second chamber section communicates with the first chamber section. The first chamber section includes an inlet for receiving a material into the filler instrument, and the second chamber section includes an outlet for discharging the material from the filler instrument. A first plunger is sized to pass through the first chamber section and not the second chamber section. A second plunger is sized to pass through an interior bore of the first plunger and into the second chamber section. In use, the first plunger displaces material residing in the first chamber section through the second chamber section toward the outlet, and the second plunger displaces material residing in the second chamber section through the outlet.

Abstract: An apparatus useful for umbilical cord care and method of its use are disclosed. The apparatus provides an injector that is detachably connected to a disposable applicator. The umbilical cord care apparatus may be provided as a kit, particularly suited for use at home.

Abstract: A retracting needle assembly for use with a syringe barrel having a cylindrical collar and a plunger having a release element with a sharp distal end includes an outer hub having a passageway therethrough and an inner hub having a proximal end, a distal end and a conduit therethrough. The proximal end of the inner hub has an inner portion and a dissociable outer portion connected to the inner portion. The dissociable outer portion is further connected to the outer hub. The distal end of the inner hub is smaller than the passageway of the outer hub at the distal end of the outer hub and projects distally outwardly therefrom. A needle cannula having a distal end, a proximal end, and a lumen therethrough is connected to the inner hub so that the lumen is in fluid communication with the conduit. An energized spring is contained between the inner and outer hub. Structure is provided for connecting the outer hub to the collar of the syringe barrel.

Abstract: The invention comprises a disposable hypodermic syringe with means for passive aspiration. The syringe comprises a barrel (10) of clear synthetic plastics material and a plunger (12) comprising an elastic bung (28) slideable in the barrel (10). Pressure on the plunger elastically deforms the bung (28). If this pressure is released the bung (28) resiles to effect aspiration. This aspiration is passive, requiring no active withdrawal of the plunger by the user. After use the syringe may be disposed of as a whole, with no disassembly, using one hand only. The syringe may be made by adapting cartridges conventionally used for dental local anaesthetic.

Abstract: The present invention provides an auto-injection device including a housing, a container from which a product is dispensed by advancing a piston, the container shiftably accommodated by the housing and carrying a needle, and a drive unit including a driven member, wherein the driven member is shiftably accommodated by the housing and, during an auto-injection, is adapted for inserting the needle and advancing the container to a predetermined frontal position in relation to the housing and advancing the piston within the container for dispensing of the product, wherein the driven member remains uncoupled with the piston until the container reaches its frontal position, and upon the container reaching its frontal position, the driven member detaches from the container and couples with the piston for advancing the piston within the container.