Abstract: The invention relates to the use of a thermoplastic molding composition which comprises at least one polybiphenyl ether sulfone polymer, to produce moldings for conveying gas.

Abstract: Multi-armed, monofunctional, and hydrolytically stable polymers are described having the structure wherein Z is a moiety that can be activated for attachment to biologically active molecules such as proteins and wherein P and Q represent linkage fragments that join polymer arms polya and polyb, respectively, to central carbon atom, C, by hydrolytically stable linkages in the absence of aromatic rings in the linkage fragments. R typically is hydrogen or methyl, but can be a linkage fragment that includes another polymer arm. A specific example is an mPEG disubstituted lysine having the structure where mPEGa and mPEGb have the structure CH3O—(CH2CH2O)nCH2CH2— where n may be the same or different for polya- and polyb- and can be from 1 to about 1,150 to provide molecular weights of from about 100 to 100,000.

Abstract: The present invention relates to a reaction system for preparing polyurethane microcellular foam, a polyurethane microcellular foam and the use thereof. The reaction system for preparing polyurethane microcellular foam comprises isocyanate prepolymer, polyols, catalysts and chain extenders. The isocyanate prepolymer is a reaction product of polyisocyanates and polyester polyols, wherein the polyester polyols comprise 10-60 wt. % succinic acid units, based on 100 wt. % of the polyester polyols, the NCO content of the isocyanate prepolymer is 13-30 wt. %, based on 100 wt. % of isocyanate prepolymer. By using the reaction components provided in the present invention, the demould time for preparing the polyurethane microcellular foam can be reduced. The obtained polyurethane microcellular foam, which possesses good physical and mechanical properties, is particularly suitable to prepare shoes.

Abstract: A multilayer film suitable for sealing containers such as used for food packaging, and methods of making the film, are described. The film is particularly suitable for sealing containers made from polylactic acid (PLA). The multilayer film includes a) a substrate that includes a polymeric base layer; and b) on the substrate, a heatseal layer containing a PLA homopolymer or copolymer. The heatseal layer further includes dispersed therein an adhesion promoter, or alternatively the substrate further includes the adhesion promoter in a layer on a surface of the polymeric base layer between and adjacent the base layer and the heatseal layer. An antifog agent may also be included in the heatseal layer or on the surface of the heatseal layer opposite the substrate.

Abstract: A process for producing hydrolysis-resistant mouldings with geometries having large dimensions by cumulative condensation of a polyamide moulding composition, is provided. The process includes mixing a polyamide moulding composition of a polyamide having at least 50% of amino end groups with 0.1 to 5% by weight, based on the polyamide moulding composition, of an oligo- or polycarbodiimide. The mixture is subsequently processed to give the moulding, wherein cumulative condensation is obtained during the processing of the moulding.

Abstract: Compositions and methods related to ophthalmic use of polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymers and therapeutic uses are described herein.

Abstract: The present invention relates to a boronated polymer according to Formula (1): a process for making the boronated polymer according to Formula (1), drug 10 delivery systems, aggregates, nanoparticles and hydrogels comprising the boronated polymer according to Formula (1).

Abstract: A resin composition comprising at least 0.1% by weight of poly(hydroxy carboxylic acid) and at least 50% by weight of polypropylene prepared with a single-site catalyst, preferably with a metallocene catalyst.

Abstract: The present invention relates to articles made of a thermoformable resin comprising a biodegradable polymer having polybutylene succinate (PBS) via extrusion using an extruder which comprise: a biodegradable polymer having: (a) a Ts value of up to about 160° C. (e.g., in the range of from about 50° to about 150° C.); (b) a heat distortion index of up to about 150° C. (for example, up to about 120° C.); and (c) optionally, a Tm in the range of from about 70° to about 160° C. (e.g., in the range of from about 80° to about 150° C.). Thermoformed article such as a food or beverage cup, lid, cutlery item, foodservice item, molded tray, food storage container, etc provide the ability to resist deformation during higher temperature conditions that may occur during storage and distribution.

Abstract: The present invention relates to methods for the production of a resin such as a thermosetting resin, particularly a bioresin, components for use in the methods, and products obtained from the methods. In one aspect the method of forming a resin comprising the steps of: (1) providing an aldehyde-cross-linking agent condensate obtained by reacting a volatile aldehyde with a cross-linking agent; (2) providing a non-volatile aldehyde; and (3) combining the aldehyde-cross-linking agent condensate and the non-volatile aldehyde, thereby forming the resin.

Abstract: Compounds are described that have both an aziridinyl group as well as a polymeric group. Methods of making these compounds are also described. The aziridinyl group of the compound can be reacted with an acidic group on a second compound resulting in the opening of the aziridinyl ring and the attachment of the polymeric group to the second compound.

Abstract: A polyarylene block copolymer can provide a solid polymer electrolyte and proton conductive membrane having high proton conductivity, high dimensional stability, and high mechanical strength. The polyarylene block copolymer also has reduced swelling in hot water and reduced shrinkage in drying. The polyarylene block copolymer includes a polymer segment having a sulfonic acid group, and a polymer segment having substantially no sulfonic acid group.

Abstract: Presently described are polymerizable ionic liquids comprising a cation and an aromatic carboxylate anion; wherein the cation, anion, or both comprise a free-radically polymerizable group. Also described are curable compositions comprising such polymerizable ionic liquids and at least one other free-radically polymerizable monomer, oligomer, or polymer.

Abstract: A proton exchange membrane comprising modified hyper-branched polymer is disclosed. The proton exchange membrane includes 85-90 wt % of sulfonated tetrafluorethylene copolymer and 15-10 wt % of modified hyper-branched polymer. The modified hyper-branched polymer comprises the bismaleimide (BMI)-based hyper-branched polymer, and parts of the chain ends of the hyper-branched polymer are sulfonated by the sulfonic compound. Also, the modified hyper-branched polymer and sulfonated tetrafluorethylene copolymer are interpenetrated to form an interpenetrating polymer. Furthermore, the modification step could be performed before or after forming the interpenetrating polymer. For example, the sulfonation is proceeded after forming the interpenetrating polymer. Alternatively, the sulfonation of the hyper-branched polymer could be proceeded before the formation of the interpenetrating polymer.

Abstract: The invention provides networked polymeric nanofibers having a structure in which amorphous polymeric fibers are branched at multiple sites and having a diameter of from 1 nanometer to 100 nanometers. A solution of a polymer such as polystyrene in a good solvent thereof is rapidly frozen to form a nanoscale phase-separation structure of the polymer and the frozen solvent. The networked polymeric nanofibers can then be obtained upon removing the frozen solvent.

Abstract: This disclosure relates generally to polycarbonate compositions whose hydrolysis products and residual monomer content, if any, exhibit little or no estradiol binding activity. Also disclosed are methods for making the disclosed polycarbonates and articles of manufacture comprising the disclosed polycarbonates.

Abstract: Disclosed is a polyamide molding compound having heat aging resistance for use as automobile or electrical components and composed of: (A) 27-84.99 wt % of a polyamide mixture consisting of (A1) at least one semiaromatic, semicrystalline polyamide having a melting point of 255° C. to 330° C., (A2) at least one caprolactam-containing polyamide that is different from (A1) and that has a caprolactam content of at least 50 wt %, where the total caprolactam content is 22-30 wt %, with respect to the polyamide mixture, (B) 15-65 wt % of at least one filler and reinforcing agent, (C) 0.01-3.0 wt % of at least one thermal stabilizer, and (D) 0-5.0 wt % of at least one additive, where the components (A)-(D) add up to 100 wt %.

Abstract: The present invention relates to dephenolic compounds, an example of which is shown below, which are functionalized, and polymers formed from the same. Polymers formed from the functionalized diphenolics are expected to have controllable degradation profiles, enabling them to release an active component over a desired time range. The polymers are also expected to be useful in a variety of medical applications.

Abstract: Novel biodegradable polyesteramides derived from optionally functionalized diacids and optionally functionalized diamines or from compounds having both optionally functionalized acid and optionally functionalized amine moieties, their preparation, and absorbable surgical articles fabricated therefrom, such as monofilament and multifilament sutures, films, sheets, plates, clips, staples, pins, screws, stents, stent coatings, packaging materials, and other implantable surgical devices, and the like, are described herein.

Abstract: The present invention relates to polymer, homo- or copolymer or oligomer for the photoalignment of liquid crystals comprising a main chain and a side chain, wherein the side chain comprises a difluoromethylene group, compositions thereof, and its use for optical and electro optical devices, especially liquid crystal devices (LCDs).

Abstract: Multi-armed, monofunctional, and hydrolytically stable polymers are described having the structure wherein Z is a moiety that can be activated for attachment to biologically active molecules such as proteins and wherein P and Q represent linkage fragments that join polymer arms polya and polyb, respectively, to central carbon atom, C, by hydrolytically stable linkages in the absence of aromatic rings in the linkage fragments. R typically is hydrogen or methyl, but can be a linkage fragment that includes another polymer arm. A specific example is an mPEG disubstituted lysine having the structure where mPEGa and mPEGb have the structure CH3O—(CH2CH2O)nCH2CH2— wherein n may be the same or different for polya- and polyb- and can be from 1 to about 1,150 to provide molecular weights of from about 100 to 100,000.

Abstract: The present application is directed to biodegradable polymers, compositions, including microspheres and nanospheres, formed of such polymers, and methods of using such polymers and compositions. In certain embodiments, the subject polymer compositions include therapeutic agents, optionally providing sustained release of the encapsulated agent after administration to a patient.

Abstract: A thermoset polyurethane composition having excellent impact and optical properties is prepared from a formulation comprising at least a prepolymer and a chain extender. The prepolymer includes an isocyanate component, containing 1,3-bis(isocyanatomethyl)cyclohexane and at least (20) percent by weight of 1,4-bis(isocyanatomethyl)cyclohexane, and an isocyanate-reactive component, containing hydroxyl, amine or thiol functionality. The isocyanate-reactive component includes from (70) to (95) percent by weight of a compound having a molecular weight from 150 to less than 950 Daltons, and from (5) to (30) percent by weight of a compound having a molecular weight from 2,000 to 4,500 Daltons. The chain extender is an aromatic, aliphatic, or cycloaliphatic polyamine compound containing at least one hydroxyl and/or thiol group. Articles that may be prepared include ophthalmic lenses, vehicle glazings, aircraft canopies, and the like.

Abstract: An optical film material suitable for use in low curl or curl free optical film-to-paper laminates is provided. The inventive optical film material includes a light-transmitting polymeric optical spacer or carrier film that has a linear coefficient of thermal expansion (CTE) of less than about 25×10?6 mm/mm-° C. over the temperature range of from about 70 to about 160° C., or that is hygroscopic (e.g., has an ambient moisture absorption, measured as a percentage moisture content, similar to paper), or both. Also provided is an optical film-to-paper laminate (e.g., a micro-optic film-to-passport paper laminate) that demonstrates a reduction in (or elimination of) curl. The inventive laminate exhibits a maximum out-of-plane deformation of less than about 10%.

Abstract: Non-natural oligomers have recently shown promise as functional analogues of lung surfactant proteins Band C (SP-B and SP-C), two helical and amphiphilic proteins that are clitical for normal respiration. The generation of non-natural mimics of SP-B and SP-C has previously been restlicted to step-by-step, sequence-specific synthesis, which results in discrete oligomers that are intended to manifest specific structural attributes. Presented herein an alternative approach to SP-R mimicry that is based on sequence-random copolymers containing cationic and lipophilic subunits. These materials, members of the nylon-3 family, arc prepared by ling-opening polymelization of 13-lactams. The best of the nylon-3 polymers display promising in vitro surfactant activities in a mixed lipid film. Pulsating bubble surfactometry data indicate that films containing the most surface-active polymers attain adsorptive and dynamic-cycling properties that surpass those of discrete peptides intended to mimic SP-B.

Abstract: The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a multifunctional nanoconjugate of temozolomide (TMZ) by conjugating TMZ in its hydrazide form to a polymalic acid platform. In another embodiment, the polymalic acid platform is conjugated to a monoclonal antibody to transferrin receptor, a trileucine (LLL) moiety, and/or a polyethylene glycol (PEG) moiety. The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a multifunctional nanoconjugate of temozolomide (TMZ) by conjugating TMZ in its hydrazide form to a polymalic acid platform. In another embodiment, the polymalic acid platform is conjugated to a monoclonal antibody to transferrin receptor, a trileucine (LLL) moiety, and/or a polyethylene glycol (PEG) moiety.

Abstract: The invention provides methods for making copolymers and multi-arm block copolymers useful as drug delivery vehicles. The multi-arm block copolymers comprise a central core molecule, such as a residue of a polyol, and at least three copolymer arms covalently attached to the central core molecule, each copolymer arm comprising an inner hydrophobic polymer segment covalently attached to the central core molecule and an outer hydrophilic polymer segment covalently attached to the hydrophobic polymer segment, wherein the central core molecule and the hydrophobic polymer segment define a hydrophobic core region. The solubility of hydrophobic biologically active agents can be improved by entrapment within the hydrophobic core region of the block copolymer. The invention further includes pharmaceutical compositions including such block copolymers, pharmaceutical compositions, and methods of using the block copolymers as drug delivery vehicles.

Abstract: Methods of manufacturing a three-dimensional, biodegradable, thermoset polymeric network composition having desirable degradation and mechanical properties, comprising a macromer component cross-linked with a monofunctional acrylate-containing component. The macromer component can comprise a diacrylate-containing component polymerized with an amine-containing component, wherein the molar ratio of the diacrylate-containing component to the amine-containing component is greater than or equal to 1.

Abstract: There is disclosed a composition formed by a reaction of at least one component A and at least one component B, wherein component A is selected from the group consisting of a compound comprising at least two thiol-groups and a disulfide derivative of a compound comprising at least two thiol groups, and wherein component B is a compound comprising at least two vinyl groups, for the manufacture of an implant for the treatment of a bone fracture. Advantages include that the adhesive patch formed by the composition will be solid in body fluid upon curing and will exhibit excellent mechanical strength. Advantages include that the composition is biocompatible, the material can be applied in small and inaccessible areas, the process requires less surgeon training, it solves drawback with open surgery, and it is possible to use cost effective materials and methods in the process.

Abstract: A resin composition comprising at least 0.1% by weight of poly(hydroxy carboxylic acid) and at least 50% by weight of polar low density polyethylene, the pLDPE comprising from 0.5 to 25% by weight of a polar vinyl-containing comonomer.

Abstract: Provided in this invention are polyethylene terephthalate resins which can suppress the formation of acetaldehyde as a by-product in melt molding of the resins and can provide the molded products reduced in acetaldehyde content. A polyethylene terephthalate resin which has an intrinsic viscosity [?2] of not less than 0.70 dl/g and not more than 1.50 dl/g and an acetaldehyde content [AA0 (ppm by weight)] of not more than 10 ppm by weight, and has such properties that the acetaldehyde content [AA1 (ppm by weight)] of the molded product obtained by injection molding the resin at 280° C. with its moisture content adjusted to 30±20 ppm by weight and the acetaldehyde content [AA2 (ppm by weight)] of the molded product obtained by injection molding the resin at 280° C. with its moisture content adjusted to 120±20 ppm by weight satisfy the following formula (1): [(AA1?AA2)/AA1]×100?30??(1).

Abstract: According to example embodiments, an organic passivation layer composition includes a cross-linking agent and an oligomer or a polymer including structural units represented by the following Chemical Formulae 1 and 2: In Chemical Formulae 1 and 2, each substituent is defined in the detailed description.

Abstract: Provided are a polyimide resin composition containing a polyimide obtained by the condensation of: a diamine component containing an aromatic diamine (A) represented by the general formula (1-1) or the like, a silicone diamine (B) represented by the general formula (2) and an aliphatic diamine (C) represented by the general formula (3); and an acid anhydride component containing a specific aromatic tetracarboxylic dianhydride (D); and a laminate and a device using the polyimide resin composition.

Abstract: Substrates, optionally coated with an undercoating, having grafted thereto one or more non-fouling materials are described herein. The non-fouling, polymeric material can be grafted to a variety of functionalized substrate materials, particularly polymeric substrates and/or polymeric undercoatings immobilized on a substrate. The compositions described herein are highly resistant protein absorption, particularly in complex media and retain a high degree of non-fouling activity over long periods of time. The compositions described herein may also demonstrate antimicrobial and/or anti-thrombogenic activity. The non-fouling material can be grafted to a functionalized substrate, or optionally from an undercoating on the substrate, preferably without significantly affecting the mechanical and/or physical properties of the substrate material.

Abstract: The present disclosure describes a coating for a surgical filament including a vinyl lactam polymer and a lactone polymer.

Abstract: The present invention discloses a vesicle which is excellent in structure stability and environmental responsiveness and also can be produced by a simple operation. More particularly, the present invention discloses a vesicle comprising a membrane formed of a first block copolymer containing a non-chargeable hydrophilic segment and a chargeable segment, and a second block copolymer containing a non-chargeable hydrophilic segment and a chargeable segment having an electric charge which is opposite to that of the chargeable segment of the first block copolymer.

Abstract: Methods for preparing conjugates using polymeric reagents bearing a maleimide are provided. Also provided are compositions comprising the conjugates.

Abstract: The invention encompasses formulations for increased attachment and retention systems of biologically active organic compounds and methods for the preparation and use thereof.

Abstract: It is an object of the present invention to provide a resin composition having improved heat resistance (high crystallinity) and transparency without impairing rigidity intrinsic to a polylactic acid based resin, a molded body formed from the resin composition, and a new polylactic acid based resin used in the resin composition. A polylactic acid based resin (A) according to the present invention is characterized by having a specific structural moiety and a weight average molecular weight (Mw) of 5,000 to 1,000,000. A polylactic acid based resin composition according to the present invention is characterized by containing the above-described polylactic acid based resin (A).

Abstract: Zwitterionic block copolymers and zwitterionic conjugates that advantageously self-assemble into particles, particles assembled from the zwitterionic block copolymers and zwitterionic conjugates, pharmaceutical compositions that include the self-assembled particles, and methods for delivering therapeutic and diagnostic agents using the particles.

Abstract: A resin composition comprising at least 0.1% by weight of poly(hydroxy carboxylic acid) and at least 50% by weight of polyethylene prepared with a single-site catalyst, preferably a metallocene.

Abstract: Disclosed are a medical instrument and a medical material each comprising an aliphatic polyester resin composition, which are hardly reduced in strength and impact resistance upon the sterilization by ionizing radiation or have excellent shape-retaining properties after a heat treatment. Specifically, a medical instrument and a medical material both sterilized by ionizing radiation are provided, each of which contains a biodegradable resin and a polycarbodiimide compound in an amount of 0.1 to 10% by weight on the resin. The biodegradable resin is polybutylene succinate, a copolymer of polybutylene succinate, or a mixture of polybutylene succinate and a copolymer of polybutylene succinate with polylactic acid or poly(3-hydroxyalkanoate). A method of producing such medical instrument and medical material is also provided.

Abstract: A resin composition comprising a polyamideimide and a polyfunctional glycidyl compound, the polyamideimide having 2 or more carboxyl groups on at least one end of the molecular chain.

Abstract: Polyamide composition comprising a first polyamide, characterized in that the composition further comprises polyamide 4,10 in an amount of at least 0.01 wt %, based on the total amount of polyamides in the composition. In a preferred embodiment of the invention, the first polyamide is an aliphatic polyamide chosen from the group of polyamide 6, polyamide 6,6 and polyamide 4,6.

Abstract: A one pot method of preparing cyclic carbonyl compounds comprising an active pendant pentafluorophenyl carbonate group is disclosed. The cyclic carbonyl compounds can be polymerized by ring opening methods to form ROP polymers comprising repeat units comprising a side chain pentafluorophenyl carbonate group. Using a suitable nucleophile, the pendant pentafluorophenyl carbonate group can be selectively transformed into a variety of other functional groups before or after the ring opening polymerization.

Abstract: Dental cement composition comprising a polymerizable polyacidic polymer having repeating units in the polymer backbone, which are represented by the following formula (I)1 (II), and/or (III): wherein X represents O, S, or NR?, whereby R? represents a hydrogen atom or a straight or branched C1-C6 alkyl group, C3-C6 cycloalkyl group, or C4-C8 cycloalkylalkyl group, Y a group of the following formula (IV), wherein each of L1, L2, L3 and L4, which are independent from each other represents a single bond, a straight or branched C1-C6 alkylene group, a straight or branched C1-C6 alkenylene, or a straight or branched C1-C20 alkylene group which includes 1 to 8 atoms selected from oxygen and sulfur atoms, X? represents O, S, or NR?, whereby R? represents a hydrogen atom or a straight or branched C1-C6 alkyl group, C3-C6 cycloalkyl group, or C4-C8 cycloalkylalkyl group, m is 0 to 3, and n is 1 to 3.

Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.

Abstract: Methods for constructing tyrosine-derived biotinylated polymers. Biotinylated polymers and polymer scaffolds constructed with the biotinylated polymers are also disclosed.

Abstract: The present invention relates to a polymer obtained from the polymerization of: (i) at least one monomer of formula (I) (CH2?CR1)CO—K (I) wherein: K represents 0-Z or NH—Z, Z representing (CR2R3)m—CH3, (CH2—CH2—O)m—H, (CH2—CH2—O)m—CH3, (CH2)m—NR4R5 with m representing an integer from 1 to 30; R1, R2, R3, R4 and R5 independently represent H or a C1-C6 alkyl; and (ii) at least one bio-resorbable block copolymer cross-linker.

Abstract: The invention concerns processes for the production of multiarmed star copolymers comprising polymerizing vinyl chloride with a multifunctional initiator in the presence of Na2S2O4 and water. The invention also concerns polymers made from the processes and articles made from the polymers.