Treating Material Forced Into Or Out Of Body By Self-acting Fluid Pressure, Motor-driven, Or Mechanical Energy Storing Means (e.g., Pressure Infusion Or Aspiration, Etc.) Patents (Class 604/131)
  • Patent number: 8945051
    Abstract: A multi-fluid injector system and methods of operation thereof are presented. One embodiment of such a fluid injector system includes a powered injector, a pressure jacket support, a syringe pressure jacket, and a syringe. The pressure jacket support includes a front plate and a rear plate. The rear plate is connected to the injector and the front plate is spaced from the rear plate and defines a slot. The syringe pressure jacket has a proximal end pivotally connected to the rear plate so that a distal end of the pressure jacket pivots relative to the front plate. The syringe has a syringe body with a distally extending discharge conduit. With the syringe disposed in a barrel of the pressure jacket, pivotal movement of the pressure jacket results in the distal end thereof pivoting toward the front plate to place the discharge conduit within the slot in the front plate.
    Type: Grant
    Filed: July 20, 2010
    Date of Patent: February 3, 2015
    Assignee: Bayer Medical Care Inc.
    Inventors: Ralph H. Schriver, Jerry A. Stokes, Michael Riley, Michael Spohn, Patrick B. Campbell, James A. Dedig, William D. Barlow, Andreas Maihoefer, Thomas P. Joyce
  • Patent number: 8939930
    Abstract: The accuracy of drug delivery with drug pump devices may be improved by a combination of pump operation at high flow resistances and pump pressures, pressure-relief mechanisms, and sensor-based feedback for pump control.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: January 27, 2015
    Assignee: MiniPumps, LLC
    Inventors: Po-Ying Li, Jonathan Lee, Alice Lai, Yu-Chong Tai, Sean Caffey, Stuart Long
  • Patent number: 8939933
    Abstract: Systems, methods, and apparatuses are provided for delivering reduced pressure to a subcutaneous tissue site, such as a bone tissue site. In one instance, a manifold for providing reduced pressure to a subcutaneous tissue includes a longitudinal manifold body formed with at least one purging lumen and a reduced-pressure lumen. The manifold further includes a plurality of manifolding surface features or slits formed on the second, tissue-facing side of the longitudinal manifold body and a plurality of apertures formed in the longitudinal manifold body on the second, tissue-facing side. The plurality of apertures fluidly couple the reduced-pressure lumen and the manifolding surface features or slits. The manifold further includes an end cap fluidly coupling the reduced-pressure lumen and the at least one purging lumen. Other systems, apparatuses, and methods are presented.
    Type: Grant
    Filed: December 24, 2009
    Date of Patent: January 27, 2015
    Assignee: KCI Licensing, Inc.
    Inventors: Carl Joseph Santora, Michael E. Manwaring, Douglas A. Cornet, Justin Alexander Long, Larry D. Swain
  • Patent number: 8936755
    Abstract: Disclosed is an apparatus for analyzing the composition of bodily fluid. The apparatus can include a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient and a pump unit in operative engagement with the fluid handling network. The pump unit can have an infusion mode, in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode, in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus can include a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: January 20, 2015
    Assignee: OptiScan Biomedical Corporation
    Inventors: Jennifer H. Gable, James R. Braig, Kenneth I. Li, Mark Wechsler, Peng Zheng, Richard Keenan
  • Patent number: 8936572
    Abstract: Included are embodiments of an ambulatory infusion device. Some embodiments include a battery receiving portion that receives a user-replaceable battery of variable individual characteristics. The user-replaceable battery may serve as a primary power source of the ambulatory infusion device and being successively depleted during application. Similarly, some embodiments include a dosing unit with an electrically powered actuator and an electronic controller that controls operation of the ambulatory infusion device. Still some embodiments include a testing unit that is operatively coupled to the electronic controller, the testing unit being designed to carry out a battery test, the battery test including determining an off-circuit voltage and an internal resistance of the user-replaceable battery. Still some embodiments include an alerting unit that is operatively coupled to the testing unit and/or the electronic controller to provide an alert to a device user in dependence of a battery test result.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: January 20, 2015
    Assignee: Roche Diagnostics International AG
    Inventors: Thomas Rufer, Reto Aeschlimann, Axel Remde
  • Publication number: 20150018612
    Abstract: Provided is a medical device including a plurality of storage units each configured to store a different medicine, and a medicine discharge unit configured to selectively discharge at least one of a first medicine and a second medicine, each of which is stored in the plurality of storage units, when the medical device reaches a periphery of a predetermined site of an intracorporeal site of a subject.
    Type: Application
    Filed: January 30, 2013
    Publication date: January 15, 2015
    Applicant: Sony Corporation
    Inventors: Akira Tange, Yoichiro Sako, Yuki Koga, Katsumi Ando
  • Patent number: 8932252
    Abstract: An apparatus includes a simulated medicament delivery device and an electronic circuit system coupled to the simulated medicament delivery device. The electronic circuit system is configured to output an electronic output associated with a use of the simulated medicament delivery device.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: January 13, 2015
    Assignee: kaleo, Inc.
    Inventors: Eric S. Edwards, Evan T. Edwards, Mark J. Licata, Paul F. Meyers, T. Spencer Williamson, Kai R. Worrell, David A. Weinzierl
  • Patent number: 8932256
    Abstract: An insertion device may include a device housing configured to be operatively engaged with and disengaged from a base, and engageable with an actuation device, the device housing having a carrier body supporting a piercing member. The carrier body moveable by a carrier body of the actuation device at least between a retracted position and an advanced position. The device housing having a section for supporting a portion of the carrier body of the device housing, the section moveable relative to the carrier body of the device housing to provide sufficient clearance to allow the carrier body of the device housing to be moved by the carrier body of the actuation device.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: January 13, 2015
    Assignee: Medtronic Minimed, Inc.
    Inventors: Colin A. Chong, Eric M. Lorenzen, Rafael Bikovsky, Arsen Ibranyan, Adam J. Livingston, Tom McGee, Steven Masterson
  • Patent number: 8932255
    Abstract: Various sealing structures are used in a front-loading injector, for preventing leakage of spilled fluid from an external surface of a syringe into the vicinity of the drive ram. For example, a sealing gasket may be incorporated into the front face of the injector housing, for mating to the rearward circular edge of the cylindrical body of a syringe. Alternatively, sealing and locking functions may be performed by a single structure on the rearward end of the syringe. Further, leakage may be prevented by including a non-planar sealing flange on the syringe, positioned on the syringe forward of the locking structure, or by a two-piece structure, including a syringe and a separate leakage stopping washer for surrounding the syringe to halt the flow of fluid along the exterior of the syringe. (As part of this aspect, or as an independent feature, the syringe may include an annularly discontinuous flange forward of the locking structure, for providing mechanical support for the syringe against the injector.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: January 13, 2015
    Assignee: Mallinckrodt LLC
    Inventors: Frank M. Fago, Robert Ziemba, Gary S. Wagner
  • Publication number: 20150011976
    Abstract: An active agent or drug injecting device (10) includes a main housing (16) containing a trigger mechanism (24) which can be manually activated via release bar (32) or remotely triggered via wireless receiver (70) activating motor (74), and a second housing (80) containing an injection- and needle-assembly (22). The needle (30) encloses a dry carrier (26) having an active agent (12) disposed thereon. The trigger mechanism triggers the injection assembly to propel the needle into the skin (via spring (54)), to inject the active agent into a living organism (either by letting the active agent diffuse out of the needle or by actively flushing it out), and to subsequently retract the needle back into the housing (80) (via spring (64)).
    Type: Application
    Filed: January 30, 2013
    Publication date: January 8, 2015
    Inventors: Lucien Vouillamoz, Melissa Rosen, Judy L. Walish, Daniel Yasevac, Michel Bruehwiler
  • Patent number: 8926566
    Abstract: Medicament delivery device comprising an elongated housing (10) comprising a grip member (64) connected to the elongated housing and movable between a rest position in which the device has a predetermined grip size and an operation position in which the pre-determined grip size of the device is increased for providing an improved grip of the device during use.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: January 6, 2015
    Assignee: SHL Group AB
    Inventor: Jochen Ratjen
  • Patent number: 8926550
    Abstract: A portable peritoneal dialysis apparatus having a USB interface for uploading and downloading patient files and records using a USB flash drive, and for playing a training video for the PD machine on the machine's own display, transferred via a USB flash drive.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: January 6, 2015
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Kulwinder S. Plahey, Tri Ly
  • Patent number: 8926561
    Abstract: Embodiments are directed to portable infusion devices, systems, and methods of using the same for dispensing materials. In some cases, the devices, systems and methods may be used for infusing a material such as medicament, e.g., insulin, into a body in need thereof.
    Type: Grant
    Filed: July 29, 2010
    Date of Patent: January 6, 2015
    Assignee: Tandem Diabetes Care, Inc.
    Inventors: Erik T. Verhoef, Paul M. DiPerna, Mike Rosinko, Mark Williamson, Geoffrey A. Kruse, Thomas R. Ulrich, Phil Lamb, Sean Saint, Michael Michaud, William Trevaskis
  • Patent number: 8926558
    Abstract: A medicament delivery device comprising a housing (10; 110); a medicament container holder (12; 120) rotatably locked but slidable connected to said housing, the medicament holder comprising first mix engagement means (28; 126) on its outer surface, and second linear guide means; a multi-chamber medicament container (14; 130) arranged within the container holder, a plunger rod (60; 140) comprising first holding means (58; 146) on its outer circumferential surface; drive force means (64; 142) capable of pushing said plunger rod; characterized in that said device further comprises manual mixing means (44, 148) comprising a rotatable manual knob (62,186) protruding from the distal end of the housing and a mix member (48, 149) comprising flexible holding means (52; 160) releasibly engaged to the first holding means (58; 146) for holding the plunger rod and thereby the drive force means in a pre-tensioned state and second mix engagement means (46; 150) arranged to cooperate with the first mix engagement means (28;
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: January 6, 2015
    Assignee: SHL Group AB
    Inventors: Jochen Ratjen, Anders Holmqvist, Martin Karlsson
  • Patent number: 8926553
    Abstract: An injection device having a drive mechanism to expel selectively a dose of medicament from a medicament cartridge through a needle unit is disclosed. The injection device further comprises an electronic control unit to control the drive mechanism, and a dispense button to generate a dispense button signal to the electronic control unit indicative of the dose to be expelled in which an arm button causes a first arm button signal to be sent to the electronic control unit to permit the dose to be expelled.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: January 6, 2015
    Inventors: Christopher Nigel Langley, Shane Alistair Day, Robert Frederick Veasey, Robert Woolston
  • Patent number: 8920374
    Abstract: An automatic injector includes a housing having a guide, a drive control mechanism, a transmission assembly, a motor, and an energy source. The housing may further include a cartridge cover. A drive control mechanism includes a drive screw, a cartridge carrier, a plunger carrier, and one or more control transfer instruments, such as a puck or cylinder. The drive screw interfaces and connects with the plunger carrier. The automatic injector is configured to accept a variety of syringes as cartridges for drug delivery. The cartridges may be ejected from the injector and safely disposed after use, making the injector a reusable automatic injector. The reusable automatic injector may further include one or more sensors, such as a cartridge sensor and a patient sensor.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: December 30, 2014
    Assignee: Unitract Syringe Pty Ltd
    Inventors: Kevin Bokelman, George M. Wohlhieter, Thomas F. McGee, Arthur G. Marlin, Stefanie A. Hurowitz, David R. Jansen, Ellen Ni Chathail
  • Patent number: 8924023
    Abstract: A method for evaluating dosing from an implanted infusion system that includes receiving input regarding the identity of a therapeutic agent into an external device. The method further includes displaying on the external device a predetermined set of symptoms associated with the therapeutic agent; receiving input into the external device regarding with which of the symptoms the patient presents; and determining whether the therapeutic agent is being delivered, or has been delivered, at an appropriate dose based on the input identity of the therapeutic agent and the input symptoms.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: December 30, 2014
    Assignee: Medtronic, Inc.
    Inventor: Emem Akpan
  • Patent number: 8920377
    Abstract: An apparatus includes a housing, a medicament container, an actuator, and a biasing member. The actuator is configured to move the medicament container within the housing when the actuator is moved from a first configuration to a second configuration. The actuator includes a gas container and a puncturer. When the actuator is in the first configuration, a portion of the puncturer is disposed apart from the gas container. When the actuator is in the second configuration, the portion of the puncturer is disposed within the gas container. The gas container has a longitudinal axis offset from a longitudinal axis of the medicament container. The biasing member is configured to bias the actuator toward the second configuration.
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: December 30, 2014
    Assignee: kaleo, Inc.
    Inventors: Eric S. Edwards, Evan T. Edwards
  • Patent number: 8920376
    Abstract: The filling status of a drug reservoir in a drug pump devices may be determined with mechanical and/or magnetic position sensor associated with a reservoir boundary.
    Type: Grant
    Filed: April 20, 2011
    Date of Patent: December 30, 2014
    Assignee: MiniPumps, LLC
    Inventors: Sean Caffey, Po-Ying Li, Yu-Chong Tai, Jeffrey Brennan
  • Patent number: 8920386
    Abstract: A one-way valve (1) comprises a seat (5) and a membrane (4) having an inner portion (4a) that is stretched over the seat, wherein, in use, the inner membrane portion is selectively deflected from the seat such that a fluid path is created from one side of the membrane to the other so as to open the valve, and wherein an outer peripheral portion (4b) of the membrane is stiffer than the inner portion such that the membrane deflection is substantially restricted to only the inner portion. The one-way valve may be used in a pump for an infusion system.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: December 30, 2014
    Assignee: Cellnovo, Ltd.
    Inventors: Joseph John Cefai, Julian Llewellyn Shapley
  • Patent number: 8915881
    Abstract: The invention relates to a injection device, comprising a housing being adapted to receive in its proximal housing portion a container with an injection fluid and to receive in its distal housing portion a dose setting and injection mechanism, wherein the mechanism includes a piston rod being axially displaceable with respect to the housing for dispensing injection fluid from the container, wherein the piston rod has an outer thread and is arranged torque proof with respect to the housing, dose setting means comprising a threaded element, which threaded element has an inner thread being in engagement with the outer thread of the piston rod, is designed so that its axial position relative to the housing is changeable and is rotatable relative to the piston rod and relative to the housing during setting of an injection dose, wherein the dose setting means are designed such that the threaded element is held in torque proof manner relative to the piston rod and to the housing during the injection of the beforehan
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: December 23, 2014
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Schabbach, Axel Roth, Gerhard Hambrecht
  • Patent number: 8905970
    Abstract: A high pressure delivery device for delivering a medicament includes a first chamber for storing a supply of the medicament and a second chamber in fluid communication with the first chamber. A fluid connection path is in fluid communication with the second chamber for administering the medicament. A valving system is in fluid communication with the first chamber, the second chamber and the fluid connection path. The valving system allows a dose of the medicament to be injected from the first chamber into the second chamber while substantially preventing backflow of the dose into the first chamber and substantially preventing leakage through the fluid connection path. The valving system also allows the dose in the second chamber to be administered through the fluid connection path while substantially preventing the dose from flowing back into the first chamber.
    Type: Grant
    Filed: July 17, 2009
    Date of Patent: December 9, 2014
    Assignee: Becton, Dickinson and Company
    Inventors: James Bates, Robert Banik, Barry Ginsberg
  • Patent number: 8905977
    Abstract: A surgical stapling and severing instrument enables minimally invasive surgical procedures by having upper and lower jaws (i.e., anvil and staple channel) that are positioned with an elongate shaft and handle through a surgical opening, and in particular through a cannula of a trocar. A pair of fluid bladders (lift bags) are positioned in the staple channel beneath a proximally projecting lever tray so that transfer of fluid from the handle causes closing and clamping of the anvil. The bi-directional fluid control may be mechanically produced at the handle or by activating an electroactive polymer actuator. Once firing is sensed, an EAP plunger in a medical substance syringe inserted into the elongate shaft is activated to dispense a medical substance (e.g., anesthetics, adhesives, cauterizing substances, antibiotics, etc.) and is guided along a firing bar to a cutting surface of an E-beam placing the substance on tissue as severed.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: December 9, 2014
    Inventors: Frederick E. Shelton, Joseph C. Hueil, Jerome R. Morgan
  • Patent number: 8905995
    Abstract: Some embodiments of a wearable, disposable medicine dispensing device may include a piston rod that is advanced to dispense medicine from the device. A rotational motor may be coupled to a drive mechanism so as to carry out a certain number of revolutions and thereby displace the piston rod by a desired distance. Such a device can be used in a method of dispensing liquid medicine.
    Type: Grant
    Filed: June 19, 2012
    Date of Patent: December 9, 2014
    Assignee: Asante Solutions, Inc.
    Inventor: Morten Mernoe
  • Patent number: 8905999
    Abstract: Described herein are a method and apparatus for introducing instrumentation into the lymphatic system that can be used for physiological monitoring and/or delivery of therapy. Such instrumentation, for example, may include one or more sensors for measuring physiological variables and/or one or more instruments for delivering therapy that is adapted to be disposed within a lymphatic vessel.
    Type: Grant
    Filed: September 1, 2006
    Date of Patent: December 9, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Allan C. Shuros, Andrew P. Kramer, Tamara Colette Baynham, James Cawthra, M. Jason Brooke
  • Patent number: 8900268
    Abstract: An endoluminal and intracorporeal negative pressure, wound care treatment, and prophylaxic system 10 and method includes a pressure distributor 40 for placement substantially within an internal organ or tissue abscess 34. A fluidic communication means 22 is provided between the pressure distributor 40 and a negative pressure source 20. A collection canister 24 is provided between the negative pressure source 20 and the pressure distributor 40 for collecting any effluents 36 that may be drawn from the abscess 34 during application of negative pressure. An introducing conduit 44 is provided for introducing the pressure distributor 40 into the abscess 34. A positioning conduit 46 is provided to properly position the pressure distributor 40 within the abscess 34. Negative pressure is applied to the pressure distributor 40 in order to provide negative pressure therapy within the abscess 34.
    Type: Grant
    Filed: November 7, 2002
    Date of Patent: December 2, 2014
    Inventors: Rolf Weidenhagen, Klaus Uwe Grützner
  • Patent number: 8900189
    Abstract: Embodiments of the present disclosure are directed to devices, systems and methods for increasing the accuracy of delivery of a fluid/drug in a fluid/drug delivery device/system. In some embodiments, a fluid infusion device is provided for delivering a drug into the body of a user, and includes at least one housing, a reservoir, a plunger and a drive-screw, where the drive-screw includes a first end and a second end, the first end being configured to operatively connect to the plunger. The device may further include a driving mechanism comprising at least a motor and one or more gears, where the one or more gears include a rotating sleeve configured for engagement with the second end of the drive-screw, a controller for at least controlling operation of the driving mechanism, and a support casing configured to substantially support the rotating sleeve and enable substantially free rotation of the rotating sleeve therein.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: December 2, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Ofer Yodfat, Shai Ben-David, Yair Dan
  • Patent number: 8900190
    Abstract: A first device housing may be configured to be operatively engaged with and disengaged from a base carried by a user and may include a first carrier body arranged for movement at least between a refracted position and an advanced position. The first carrier body may support a piercing member for insertion through skin of the patient. A second device housing may be configured to be operatively engaged with and disengaged from the first device housing and may include a second carrier body operatively connectable with the first carrier body and arranged for movement at least between a retracted position and an advanced position. A driver in the second device housing may be arranged to move the first carrier body toward the advanced position to insert at least a portion of the piercing member through skin of the patient.
    Type: Grant
    Filed: September 2, 2009
    Date of Patent: December 2, 2014
    Assignee: Medtronic Minimed, Inc.
    Inventors: Colin A. Chong, Eric M. Lorenzen, Rafael Bikovsky, Arsen Ibranyan, Julian D. Kavazov
  • Publication number: 20140350467
    Abstract: Devices and methods for delivering a therapeutic agent to a patient are disclosed herein. In one embodiment, a delivery system includes a reservoir containing a fluid and a fluid communicator in fluid communication with the reservoir. An actuator is coupled to the reservoir and configured to displace and exert a force on the reservoir for a time period upon actuation such that fluid within the reservoir is communicated through the fluid communicator. An amplification mechanism is coupled to the actuator. The amplification mechanism is configured to increase at least one of the force, the displacement, or the time period the force is exerted by the actuator on the reservoir. In some embodiments, a transfer structure is disposed between the amplification mechanism and the reservoir. The transfer structure is configured to contact the reservoir upon actuation of the actuator. In some embodiments, the actuator can be an electrochemical actuator.
    Type: Application
    Filed: January 27, 2014
    Publication date: November 27, 2014
    Applicant: SpringLeaf Therapeutics, Inc.
    Inventors: J. Richard Gyory, Alessandro Pizzochero
  • Publication number: 20140350521
    Abstract: The fluid injector system includes a source of injection fluid, a pump device, a fluid control device operably associated with the pump device, and a fluid path set in fluid connection with the source of injection fluid and the pump device. The fluid path set includes a multi-patient fluid path section adapted for fluid connection to at least one pressurizing device, a per-patient fluid path section adapted for fluid connection with a patient and comprising at least one check valve, and a connector for removably and fluidly connecting the multi-patient fluid path section with the per-patient fluid path section.
    Type: Application
    Filed: August 12, 2014
    Publication date: November 27, 2014
    Inventors: Michael A. Spohn, Michael J. Swantner
  • Publication number: 20140350469
    Abstract: A portable medical analyzer comprising a sampling module with a sample port for receiving body fluid, an assay sensor module for analysis of the body fluid, an analytical detector module with detection of information from the assay, and a communications module for transferring the information to a remote location via a wired or wireless network.
    Type: Application
    Filed: August 11, 2014
    Publication date: November 27, 2014
    Applicant: Sanofi-Aventis Deutschland GmbH
    Inventors: Domnique M. FREEMAN, Michael Higgins, Jeffrey Perry
  • Publication number: 20140350470
    Abstract: Devices and methods for delivering a fluid to a patient are disclosed herein. In one embodiment, a delivery system includes a reservoir for containing a fluid and a fluid communicator in fluid communication with the reservoir. An electrochemical actuator is coupled to the reservoir and configured to exert a force on the reservoir upon actuation such that fluid within the reservoir is communicated through the fluid communicator. The actuator includes a first end that is constrained and a second end that is not constrained. The actuator is configured to bend at a location along a length of the actuator when actuated such that the second end of the actuator is displaced in a direction toward the fluid reservoir. The actuator can be an electrochemical actuator. The apparatus can further include a transfer structure disposed between the actuator and the reservoir configured to contact the reservoir upon actuation of the actuator.
    Type: Application
    Filed: January 27, 2014
    Publication date: November 27, 2014
    Applicant: SpringLeaf Therapeutics, Inc.
    Inventors: J. Richard Gyory, Daniel Hamilton, Alessandro Pizzochero, Jon Taylor
  • Publication number: 20140350468
    Abstract: A blinding device for administering a substance to a patient in a clinical trial is presented where the blinding device has an opaque housing to receive at least two delivery devices adapted to dispense a substance provided therein, an outlet being in fluid communication with at least one delivery device for administering the substance to a patient, and at least one actuating member mechanically engageable with at least one delivery device and being actuatable from outside the housing.
    Type: Application
    Filed: January 15, 2013
    Publication date: November 27, 2014
    Inventor: Claus Cordes
  • Patent number: 8894612
    Abstract: An infusion system includes a disposable wearable infusion device and a filler device. The disposable infusion device has a body arranged to be adhered to a patient's skin and a reservoir for holding a liquid medicant to be infused into the patient. The filler device is arranged to detachably receive the infusion device body and to transfer a volume of the liquid medicant to the infusion device reservoir. The filler device may be part of a service device arranged to detachably receive the infusion device and which also includes a cannula driver and a cannula for providing the infusion device with a cannula and deploying the cannula to beneath a patient's skin.
    Type: Grant
    Filed: April 1, 2013
    Date of Patent: November 25, 2014
    Assignee: Calibra Medical, Inc.
    Inventors: Daniel Hawkins Hawkins, Brett J. Carter, John M. Adams
  • Patent number: 8888738
    Abstract: An infusion pump including a drive mechanism; an assembly operable with the drive mechanism, the assembly configured to deliver a flowable material to a patient; a mountable housing holding the drive mechanism and configured at its front side to receive the assembly and at its backside to mount in either a first orientation or a second orientation to an external support, wherein the housing supports the drive mechanism and the assembly in each of the orientations; a controller operably connected to the housing; and a display operably connected to the controller and supported by the front side of the housing, the display configured to be rotatably responsive so that information displayed by the display is oriented right-side-up regardless of whether the assembly is in the first orientation or the second orientation.
    Type: Grant
    Filed: August 10, 2011
    Date of Patent: November 18, 2014
    Assignee: Baxter International Inc.
    Inventors: John Gillespie, Jr., Ralph H. LaBedz, Michael Kenneth Platt, Ronald H. Spang, Jr., James Frei Berrill, Matthew Stephen Vogel, Michelle Kowalski Greaney
  • Patent number: 8888745
    Abstract: The invention pertains to an applicator (1) for inserting an implant, in particular a rod-like implant (2) containing an active substance, under the skin of a human or animal, comprising a housing (3), a cannula (6) extending from the housing (3), and a handle (15) for grasping and maneuvering the applicator (1) and the cannula (6) during insertion of an implant (2). In accordance with the invention, the handle (15) extends above at least part of the length of the cannula (6). Such a handle facilitates insertion of the cannula and/or accurate positioning of the implant.
    Type: Grant
    Filed: January 20, 2006
    Date of Patent: November 18, 2014
    Assignee: Merck Sharp & Dohme B.V.
    Inventors: Iris Epkjen Hobo Van Der Graaf, Maurice Petrus Wilhelmus Tak, Juergen Schmidt, Hendricus Johannes Vertegaal
  • Publication number: 20140336463
    Abstract: The herein disclosed invention is directed to methods of treating difficult to treat refractory or recalcitrant rhinosinusitis involving the steps of (1) topical application of antimicrobials/antibiotics and corticosteroids, (2) endoscopic debridement and cleansing to remove debris and biofilm, (3) endoscopic instillation of antimicrobials/antibiotics plus corticosteroids to the sinuses, and (4) hydrotherapy to disrupt/inhibit bacterial/fungal biofilm attachment to the sinus mucosa. Also disclosed is a kit of components for carrying out the treatment of this invention.
    Type: Application
    Filed: January 22, 2010
    Publication date: November 13, 2014
    Inventor: Alan H. Shikani
  • Patent number: 8882708
    Abstract: In general, this disclosure relates to techniques for providing a mating mechanism between at least one pressurizing unit and at least one corresponding sleeve in a powered medical fluid injection device. An example powered medical fluid injection device includes a sleeve and an injector head coupled to the sleeve. The sleeve has a notch with a predefined shape and size. The sleeve is configured to receive a pressurizing unit (such as a syringe) having an external tab with a predefined shape and size that are substantially identical to the predefined shape and size of the notch in the sleeve, such that the tab mates with the notch when the sleeve receives the pressurizing unit. The injector head is configured to inject a quantity of a medical fluid from the pressurizing unit during operation.
    Type: Grant
    Filed: October 30, 2008
    Date of Patent: November 11, 2014
    Assignee: ACIST Medical Systems, Inc.
    Inventors: Marty Hieb, Khoi Le, Bill West, Darryl Wrolson, Paul Pilosi
  • Patent number: 8882710
    Abstract: An insertion device may include a base adapted to be carried by a patient, and a housing attached to the base, the housing having a fluid connector arranged for movement relative to the base. A pair of interactive elements including a first interactive element may be supported on the base and a second interactive element supported on the housing at a location to be interactable with the first interactive element when the fluid connector is moved to a predetermined position. Circuitry may be configured to detect an interaction between the first interactive element and the second interactive element when the fluid connector is in the predetermined position, the circuitry configured to provide a signal or a change in state in response to detecting the interaction between the first interactive element and the second interactive element.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: November 11, 2014
    Assignee: Medtronic Minimed, Inc.
    Inventors: Colin A. Chong, Eric M. Lorenzen, Rafael Bikovsky, Arsen Ibranyan, Adam J. Livingston, Tom McGee, Steven Masterson
  • Publication number: 20140330203
    Abstract: Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The cassette unit housing cavity is arranged for receipt of a syringe. The syringe has a barrel for containing a volume of a liquid drug formulation, the barrel defining a flange at the rear end thereof and a forward shoulder at the forward end thereof; a hollow needle at a front end of the barrel, the hollow needle defining a needle tip; and a plunger that is axially movable within the barrel. The cassette unit includes, in contact with the plunger and axially movable within the barrel, a plunger slaving part arranged such that when a drive load is applied to a rear drive-receiving face thereof the drive load is evenly transmitted to the plunger.
    Type: Application
    Filed: June 4, 2012
    Publication date: November 6, 2014
    Applicant: UCB PHARMA SA
    Inventors: Martin John McLoughlin, Darrell P. Morgan, Kevin Richard Lozeau, Agnete Enga, Eric Freitag, Daniel Formosa, Michael Schumann, Brian Lipford, Jake Cowperthwaite, Alex Flamm, Ilario Melzi, Jonathan Bodnar
  • Patent number: 8876765
    Abstract: A pump module for use in a medical fluid dispensing system is provided that includes a pump body and first and second pump chambers formed in the pump body. The module further includes a pair of chamber inlets and chamber outlets formed in the pump body, each associated with one of the pump chambers. Each of the pump chambers further includes a first portion having a generally spherical segment shape and a second portion integral with the first portion and having a generally conical shape, with the first and second portions in fluid communication with the chamber inlet and the chamber outlet. The second, conically shaped portion converges to the chamber outlet.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: November 4, 2014
    Assignee: Smiths Medical ASD, Inc.
    Inventors: Stanley Paul Mack, Charles R. Patzer, Stephen L. Vick
  • Patent number: 8876802
    Abstract: Devices of this invention include replaceable cartridges for delivery of doses of fluids. Cartridges having a fluid supply reservoir comprising an expandable element are designed to be connected with non-disposable actuating module supplied with a sensor, a mechanism to apply a force to the fluid, thereby forcing a predetermined dose out of the reservoir, and a processor providing control outputs from a sensor system according to preprogrammed instructions. Methods of this invention include delivery of microdoses of fluids using devices of this invention.
    Type: Grant
    Filed: September 14, 2009
    Date of Patent: November 4, 2014
    Inventor: Leonid Grigorov
  • Publication number: 20140323917
    Abstract: These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. An analyte detecting member is positioned to receive fluid from a wound created by the penetrating member. The detection member is configured to determine a concentration of an analyte in the fluid using a sample of less than 1 ?L of the fluid. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.
    Type: Application
    Filed: July 9, 2014
    Publication date: October 30, 2014
    Applicant: Sanofi-Aventis Deutschland GmbH
    Inventors: Dominique M. Freeman, Don Alden, Dirk Boecker
  • Publication number: 20140323837
    Abstract: A needle system for penetrating to or passing thought an object or an organ comprising a semiconductor die, one or more needles, wherein the needles slide over the plane of the die, one or more actuators that move the needles relative to the die plane, and one or more actuator drivers controlled by a controller wherein the controller instruct the needle to penetrate into or to pass through and/or retract from the object or organ. The needle system is used for drug delivery or blood extraction or blood analysis or glucose measurements or blood measurements or nerve system stimulus treatment or hair removal or skin lesions removal.
    Type: Application
    Filed: July 9, 2014
    Publication date: October 30, 2014
    Inventor: David Hirshberg
  • Publication number: 20140324023
    Abstract: Accordingly, it is an aspect of the present invention to provide a medicament delivery system with a delay mechanism to ensure dose completion prior to activation of at least one subsystem or operation. The foregoing and/or other aspects of the present invention are achieved by providing a medicament delivery system, including a medicament container and a delay mechanism that is activated prior to completion of medicament delivery from the medicament container. The delay mechanism automatically activates a subsystem or initiates an operation subsequent to completion of medicament delivery. The foregoing and/or other aspects of the present invention are also achieved by providing a method of delivering a medicament, the method including receiving an activation command, and in response to receiving the activation command, releasing an ejection mechanism to eject medicament from a container.
    Type: Application
    Filed: November 20, 2012
    Publication date: October 30, 2014
    Applicant: BECTON, DICKINSON AND COMPANY
    Inventors: Peter Krijger, Philip Song, Curt Bingham, Stephen C. Simmons, Paul Alchas
  • Patent number: 8870821
    Abstract: A system for administering an injection is described. The invention consists of an adhesive patch with an integrated injector that controllably insets an injection needle and delivers the medication contained within the patch. Variations of the system may also subsequently and automatically retracts the needle, rendering the patch safely inert. In additional variations, a portion of the system may remain on the patient and function as a bandage.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: October 28, 2014
    Inventor: Michael D. Laufer
  • Patent number: 8870811
    Abstract: Peritoneal dialysis systems and related methods are disclosed. The methods can include combining a first solution having a first concentration of a solute with a second solution having a second concentration of the solute to form a custom dialysate, e.g., according to a specific prescription for a patient.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: October 28, 2014
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: David A. Gavin, Thomas I. Folden
  • Patent number: 8864722
    Abstract: The present invention relates to a cartridge holder for a drug delivery device comprising: a distal portion for receiving a cartridge filled with a medicament to be dispensed by the drug delivery device, wherein the distal portion comprises a mount for a piercing assembly, a proximal portion adapted to at least partially receive a drive mechanism having a piston rod to become operably engaged with a piston of the cartridge for expelling a dose of the medicament from the cartridge, wherein the drive mechanism comprises at least first fixing means corresponding with fixing means of the drive mechanism for directly interconnecting cartridge holder and drive mechanism.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: October 21, 2014
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Michael Helmer
  • Patent number: 8864712
    Abstract: Various sealing structures are used in a front-loading injector, for preventing leakage of spilled fluid from an external surface of a syringe into the vicinity of the drive ram. For example, a sealing gasket may be incorporated into the front face of the injector housing, for mating to the rearward circular edge of the cylindrical body of a syringe. Alternatively, sealing and locking functions may be performed by a single structure on the rearward end of the syringe. Further, leakage may be prevented by including a non-planar sealing flange on the syringe, positioned on the syringe forward of the locking structure, or by a two-piece structure, including a syringe and a separate leakage stopping washer for surrounding the syringe to halt the flow of fluid along the exterior of the syringe. (As part of this aspect, or as an independent feature, the syringe may include an annularly discontinuous flange forward of the locking structure, for providing mechanical support for the syringe against the injector.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: October 21, 2014
    Assignee: Mallinckrodt LLC
    Inventors: Frank M. Fago, Robert Ziemba, Gary S. Wagner
  • Patent number: 8858492
    Abstract: An ophthalmic surgery kit includes a priming vessel defining a reservoir for holding a fluid, an auxiliary aspiration channel, an irrigation channel, a handpiece channel, and an ophthalmic surgical handpiece retained by the handpiece channel. The ophthalmic surgical handpiece includes a tip disposed within the reservoir. An auxiliary aspiration tube 15 retained by the auxiliary aspiration channel with a first end disposed within the reservoir. An irrigation tube first end is retained by the irrigation channel within the reservoir.
    Type: Grant
    Filed: April 26, 2011
    Date of Patent: October 14, 2014
    Assignee: Bausch & Lomb Incorporated
    Inventors: Matthew J. Fitzgerald, Merlin Hall, Robert Doyle, Michael Versemann