Abstract: A pump is disclosed that comprises a primary control unit comprising a first processor and one or more modular pumping units removably docked to the primary control unit. Each modular pumping unit comprises a pumping mechanism and a second processor configured to control the pumping mechanism and communicate with the first processor. The modular pumping unit is configured to manipulate a portion of a fluid delivery set to pump a fluid. The first processor and the second processor are configured to exchange one or more operating parameters when the modular pumping unit is docked to the primary control unit. The modular pumping unit is configured to pump the fluid after being undocked.

Abstract: Dispenser and methods of dispensing substances is provided. The dispenser comprises a housing having a longitudinal axis, the housing configured to receive a packet comprising at least one collapsible cavity containing at least one substance, a support member positioned in the housing, the support member having a longitudinal axis essentially parallel to the longitudinal axis of the housing, a wedge coupled to the support member, the wedge configured to move in a plane substantially parallel within the longitudinal axis of the housing, the wedge receiving a force directed substantially normal to the longitudinal axis of the housing, and a reciprocating actuator coupled to the housing and engagable with the support member, the actuator moveable between a first position and a second position whereby the wedge advances a single predetermined increment collapsing a portion of the cavity.

Abstract: An expansion/compression mechanism of a piston rod assembly is composed of a bush shaft, a first cylindrical piston rod that is screwed with the bush shaft, a second cylindrical piston rod that is screwed with the first piston rod, and a piston rod holding member for housing the bush shaft and these piston rods. Therefore, the piston rods move linearly in multiple stages.

Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.

Abstract: A method and system for both autonomous and manual control of an infusion pump for delivering medication to a patient is provided.

Abstract: A medication and identification information transfer system is provided that includes a primary medication container, a secondary medication container, a secondary container label and a medication information transfer apparatus. The medication information transfer apparatus, when coupled to the primary medication container, can transfer information indicative of the contents of the primary medication container to a medication delivery device such as an intelligent injection site. The medication information transfer apparatus has a shape and size enabling it to be connected to an adapter for removal of medication from the primary medication container which enables transfer of the medication to a secondary container while simultaneously transferring information about the medication in the primary medication container to the injection site. In some implementations, the medication injection site can be placed on a fluid delivery line for infusion into a patient.

Abstract: The present invention discloses a vibration imparting device having an attachment mechanism 5 that supports a guiding catheter 10a to be inserted into a body, and a vibrating portion 4 that is located outside the body and imparts vibration of non-ultrasonic frequency to the guiding catheter 10a via the attachment mechanism 5. That enables a catheter to be easily inserted into a lesion area of the body.

Abstract: A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.

Abstract: A pharmaceutical delivery apparatus with an automatic syringe retraction following a manually controlled injection. The apparatus includes a housing (28), a syringe carriage (90), a medication-filled syringe (70) held within the carriage, the syringe needle tip being disposed within the housing in a first position and projecting from the housing beyond the housing proximal end for insertion into an injection site in a second position, a manually shiftable plunger (130), means on the carriage and the housing and the plunger for causing the carriage to advance from the first position to the second position and for injecting medicine from the syringe when the plunger is manually plunged proximally toward the housing, and means on the carriage and the plunger for causing the carriage to retract from the second position to a position at which the needle tip is disposed within the housing when the plunger shifts distally.

Abstract: The invention relates to a stopper arrangement for a drug delivery device, comprising a stopper, a linear actor coupled with one end to the stopper and with an opposite end to a coupling arrangement, wherein the stopper arrangement is configured to be disposed within a container of a drug delivery device, wherein a shape and/or material of the stopper and the coupling arrangement are configured such that a first frictional force between the coupling arrangement and the container is lower than a frictional force between the stopper and the container when the linear actor is contracting and that second frictional force between the coupling arrangement and the container is greater than the frictional force between the stopper and the container when the linear actor is expanding.

Abstract: A vaccination system for delivering a vaccine substance to avian pullets is provided. Such a system includes a vaccine delivery assembly configured to perform a vaccine delivery procedure for delivering a vaccine substance to the avian pullets. A plurality of positioning devices is provided, with each positioning device receiving an avian pullet for presentation to the vaccine delivery assembly. Each positioning device is transported to individually mate with the vaccine delivery assembly to deliver the vaccine substance during the vaccine delivery procedure. Associated methods, devices, and assemblies are also provided.

Abstract: A medical device used in a medical robotic system has a conduit and an orientable tip. An optical fiber coupled to a laser source and/or a catheter coupled to one or more biomaterial sources extends through the conduit and tip so that the tip of the medical device may be robotically directed towards a target tissue for laser and/or biomaterial application as part of a medical procedure performed at a surgical site within a patient. A protective sheath covers the fiber as it extends through the conduit and tip. A first coupler adjustably secures at least the sheath to the medical device and a second coupler adjustably secures the fiber to at least the sheath. A similar dual coupler mechanism may be used to secure the sheathed catheter to the medical device.

Abstract: A device for inserting at least one hollow needle for the injection or withdrawal of a solution into/from a tissue, said device comprising a casing (1), a plunger (2) movably mounted inside the casing, and propulsion means (3 and 4) suitable for driving the plunger towards the distal end (1a) of the device by applying a force F1(t). The propulsion means and/or the plunger comprise retaining means (3a) for joining the propulsion means and the plunger while the latter is moving, said retaining means releasing the plunger from the propulsion means when a force F2(t) is exerted in the opposite direction to F1(t). Pressure means hold the needle in the tissue and allow a controlled withdrawal of the plunger at least while the solution is being injected.

Abstract: A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

Abstract: A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

Abstract: RFID chip (214) having various types of data is mounted on liquid syringe (200). Chemical liquid injector (100) obtains the various types of data from RFID chip (214) to perform a predetermined operation in accordance with at least some of the various types of data. For, example, a variable pattern for liquid can be recorded on RFID chip (214) of liquid syringe (200) to allow chemical liquid injector (100) to inject the liquid in accordance with the predetermined variable pattern. Thus, a large amount of data can be easily input to the chemical liquid injector to perform the various operations.

Abstract: The present invention relates to a method for the preparation of a treatment machine for the treatment of a medical liquid comprising a coupling surface with actuators, with a cassette comprising a hard part with liquid-conducting passages which are covered by a flexible film being able to be coupled to the coupling surface of the treatment machine so that the actuators can control the liquid flow in the liquid-conducting passages by pressing the flexible film down into the cassette. In this connection, a switch is made after the setting up of the treatment machine and before the start of treatment into a stand-by mode in which the actuators are alternately moved to relieve the flexible film. It is possible for the first time by the stand-by mode before the start of treatment in accordance with the invention to completely uncouple the time-consuming setting up of the treatment machine from the treatment itself in a time aspect.

Abstract: Devices and methods are provided for fluid delivery. The device may include a housing having an outer surface which includes a porous membrane, a fluid reservoir disposed in the interior region of the main housing and formed at least in part by a wall structure, a puncture mechanism operable to puncture the wall structure and form a fluidic path between the fluid reservoir and one or more channels in fluid communication with the porous membrane, and a positive displacement mechanism operable, following puncture of the wall structure, to drive a fluid out of the fluid reservoir, through the one or more channels, and into the porous membrane.

Abstract: The present invention relates to a clamp mounting for accommodating at least one section of a drug delivery device or for restricting it in at least one direction of motion. The drug delivery device features an accommodation chamber for the drug solution or substance to be delivered. The clamp mounting features at least one clamping device. The clamping device features at least one recess which is provided for accommodating or restricting at least one part of the section of the drug delivery device. The recess or at least a section hereof has an arched or curved demarcation between itself and sections of the clamping device that are not recessed. Alternatively or additionally, the recess or at least a section hereof is arched or curved in at least one section hereof. The present invention further relates to a dosing apparatus and a blood treatment apparatus.

Abstract: A method, computer program product, and infusion pump assembly for determining a first rate-of-change force reading that corresponds to the delivery of a first dose of an infusible fluid via an infusion pump assembly. At least a second rate-of-change force reading is determined that corresponds to the delivery of at least a second dose of the infusible fluid via the infusion pump assembly. An average rate-of-change force reading is determined based, at least in part upon the first rate-of-change force reading and the at least a second rate-of-change force reading.

Abstract: Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition.

Abstract: An apparatus includes a simulated medicament delivery device and an electronic circuit system coupled to the simulated medicament delivery device. The electronic circuit system is configured to output an electronic output associated with a use of the simulated medicament delivery device.

Abstract: A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

Abstract: The present invention relates to an improved smoke evacuation device for use in laparoscopic surgeries. One improvement is a hydrophilic wick positioned within the inlet system of the smoke device for absorbing moisture and trapping surgical waste entering the smoke evacuation device. The second improvement is a multi-outlet valve inserted into the outlet system of the smoke evacuation device to enable quick depressurization of the surgical site.

Abstract: A system for delivering fluid to a patient includes a hazardous material enclosure suitable for holding a first container comprising a first fluid, and a pump device capable of pumping the first fluid from the first container and a second fluid from a second container. The hazardous materials enclosure has a cap which includes a flexible sealing member that cooperates with the first container to create a biohazard seal during connection of the first container to the cap. The system further includes a mixing device associated with the pump for mixing the first and second fluids for delivering the fluid mixture to the patient.

Abstract: A cannula insertion device includes a housing defining an opening for receiving therethrough a cannula and further defining a channel, and a cannula forming a lumen, the cannula adapted for sliding movement within the housing from a retracted position to an extended position. When the cannula is in the retracted position, the lumen is located remotely from the channel and the channel is in fluidic communication with the opening. When the cannula is in the extended position, the lumen is in fluidic communication with the channel.

Abstract: A system enables determination of at least one parameter for an injection procedure to be performed on a patient in connection with a diagnostic imaging procedure. The system includes a processor and one or more algorithms. Embodied within the algorithm(s) is a model descriptive of the propagation of a fluid within the patient from a site of injection thereof to each of at least two regions of interest thereof. The algorithm(s) permits one discrete data point from each of at least two time enhancement curves, derived via a test bolus, to be input into the model to determine values of physiological parameters associated with the patient, preferably those related to cardiopulmonary function. The algorithm(s) also allows the values of the physiological parameters to be input into the model wherein the parameter(s) of the injection procedure that will be performed on the patient at issue are determined.

Abstract: A connecting structure for connecting a first member in fluid flow connection with a second member may include a receptacle structure provided on the first member and having an interior chamber and an opening into the interior chamber in which a needle and a pierceable member surrounding a piercing end of the needle may be supported. The second member may include a connection portion that has a septum supported in an interior chamber having a size and shape suitable to be received at least partially into the opening of the receptacle structure upon moving the first member and the second member together to push the pierceable member toward the piercing end of the needle to cause the piercing end of the needle to pierce the pierceable member and the septum to come into fluid flow communication with the interior chamber of the connection portion.

Abstract: A medical injector (300) includes a medicament container (310), a non-manual actuator (320), and an adapter (340) for coupling the medicament container (310) and the non-manual actuator (320). The adapter (340) includes a proximal end portion (341) configured to engage a drive element (326) of the non-manual actuator (320). The adapter (340) also includes a distal end portion (344) including a surface (345) configured to engage a movable element (319) within the medicament container (310). The adapter (340) may include a coupler (350) having at least one coupling member (353) configured to removably couple the adapter (340) to the medicament container (310), and also having a connector (354) configured to removably couple the adapter (340) to the non-manual actuator (320). The drive element (326) of the non-manual actuator (320) may apply a movement force to the adapter (340), which then pushes the movable element (319) within the medicament container (310) to inject medicament into a patient.

Abstract: Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the osmotic pump device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.

Abstract: An injection device for injecting medication to a patient, comprising a surface (5) having a through hole (3) for passage of a needle, is characterised by further comprising a capacitive proximity sensor (12, 13, 30) for detecting proximity or contact of human skin to/with said surface (5).

Abstract: Some embodiments of a wearable, disposable medicine dispensing device may include a piston rod that is advanced to dispense medicine from the device. A rotational motor may be coupled to a drive mechanism so as to carry out a certain number of revolutions and thereby displace the piston rod by a desired distance. Such a device can be used in a method of dispensing liquid medicine.

Abstract: An infusion system for infusing a liquid into a body includes an external infusion device and a remote commander. The external infusion device includes a housing, a receiver, a processor and an indication device. The receiver is coupled to the housing and for receiving remotely generated commands. The processor is coupled to the housing and the receiver to receive remotely generated commands and to control the external infusion device in accordance with the commands. The indication device indicates when a command has been received and indicates when the command is being utilized to control the external infusion device so that the external infusion device is capable of being concealed from view when being remotely commanded. The remote commander includes a commander housing, a keypad for transmitting commands, and a transmitter for transmitting commands to the receiver of the external infusion device.

Abstract: Automatic injection device includes a housing, a syringe, a plunger, and a syringe carrier. The housing includes a barrel. The barrel includes an elongated window to allow viewing of contents inside the housing. The syringe is disposed within the housing and has a reservoir. The plunger is at least partially disposed within the syringe and includes a visual indicator. The syringe carrier is disposed within the housing and configured to contain the syringe and displace the syringe within the housing between a first position and a second position. The syringe carrier can have at least one opening and at least one pair of legs defining at least a portion of the at least one opening.

Abstract: An injection device (22) is equipped with a compartment articulated with reference to the device to receive a syringe (10) with staked needle (18) protected by a protection cap (20) coupled with the syringe, the compartment being susceptible to evolve from a first open position for the insertion and the removal of the syringe, and a second closed position for the realization of the injection. The device includes a detachment system intended to cooperate with the cap of the syringe to decouple it from the syringe, the detachment being conditioned by the passage of the compartment to its second position. Furthermore, the passage of the compartment from the second to the first position is conditioned by the coupling of the cap.

Abstract: Injection device for manual penetration and injection comprising a distal housing part (10); a proximal housing part (12) with a multi-chamber container (20); a plunger rod (40); a push button (70); an activation member (30); a drive force means(100) and a locking member (50), wherein the device further comprises a guide rod (60) arranged to generate an audible and tactile indication of the start of an injection.

Abstract: A drug delivery platform is provided for delivering a controlled infusion of a drug to an individual. The drug delivery platform includes a reservoir for receiving the drug therein and a pressure source engageable with the reservoir. The pressure source is movable between a first configuration and a second configuration wherein the pressure source exerts a pressure on the reservoir to urge the drug therefrom. An output conduit is provided for transmitting the drug into the individual. An actuation mechanism is operatively connected to the pressure source and the output conduit. The actuation mechanism is movable between a non-actuated position and an actuated position wherein pressure source moves from the first configuration to the second configuration and wherein the input of the output conduit communicates with the drug and the output end of the output conduit is receivable in the individual.

Abstract: The present disclosure provides cassettes and methods of using same for the delivery of fluids to a patient using fluid delivery systems. In a general embodiment, the cassettes of the present disclosure include a flexible tube, a housing having a recessed area and first and second ends for holding the flexible tube, and at least two additional components including, for example, different sensors, false reading components for sensors, anti-flow valve means, insertion guides, directional indicators, latch mechanisms, kink-prevention notches, etc. Such additional components provide the cassettes of the present disclosure with several advantages including, for example, quality control, efficiency of use, cost effectiveness, and safety of use.

Abstract: The invention relates to an adapter for a syringe plunger. The adapter of some embodiments may include a first side adapted to interface with a syringe plunger and an opposing a second side adapted to interface with a drive ram of a medical fluid injector. The adapter may include a peripheral side surface exhibiting a thickness and may include what may be characterized as at least one mating section adapted to engage with the syringe plunger. The mating section(s) may include a channel extending through the entire thickness of the adapter. In some embodiments, the mating section(s) may include a stop adjacent the channel that extends less than the entirety of the thickness of the adapter.

Abstract: A medical instrument for ejecting liquid includes a liquid chamber that contains the liquid, a driving unit that pressurizes the liquid contained in the liquid chamber, and a vibration detector that detects vibration when the driving unit is driven.

Abstract: Devices and methods are provided for transmucosal drug delivery. The transmucosal drug delivery device may include a housing configured for intralumenal deployment, such as intravaginally, into a human or animal subject; a drug-dispensing portion which contains at least one drug, the drug-dispensing portion being configured to dispense the drug from the housing by positive displacement; and a permeability enhancer-dispensing portion configured to release or generate a permeability enhancing substance to disrupt at least one region of a mucosal barrier adjacent to the housing at a selected time while intralumenally deployed in the human or animal subject. The device may be operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the permeability enhancing substance.

Abstract: The embodiments disclosed herein relate to various medical systems, including systems that can be used in conjunction with medical devices used in endoscopic surgery. Certain embodiments include various material handling devices that can transport materials between the inside and the outside of an endoscopic surgery patient.

Abstract: A high pressure delivery device for delivering a medicament includes a first chamber for storing a supply of the medicament and a second chamber in fluid communication with the first chamber. A fluid connection path is in fluid communication with the second chamber for administering the medicament. A valving system is in fluid communication with the first chamber, the second chamber and the fluid connection path. The valving system allows a dose of the medicament to be injected from the first chamber into the second chamber while substantially preventing backflow of the dose into the first chamber and substantially preventing leakage through the fluid connection path. The valving system also allows the dose in the second chamber to be administered through the fluid connection path while substantially preventing the dose from flowing back into the first chamber.

Abstract: A self-injection device with a miniaturized drug delivery portion is provided. The device includes a housing (10) having an interior volume and the drug delivery portion (20) has a volume enclosed within the housing. The drug delivery portion includes a reservoir (30) containing a fluid to be delivered to a user and a microneedle (22) in fluid communication with the reservoir and extendable through the housing. The drug delivery portion also includes a drive mechanism for expelling fluid from the reservoir through the microneedle, wherein the volume of the drug delivery portion is less than 40% of the interior volume of the housing. The volume of the drug delivery portion may be less than 30% of the interior volume of the housing.

Abstract: A pump apparatus that exerts a constant force on a bag of fluid to provide a uniform flow rate compared to elastomeric pumps. The apparatus comprises a first and a second block member positioned over a plate, which are moveable to define an opening to receive a wedge member attached on the plate. The block members are coupled by a resilient means that is extendable when the wedge member is urged into the opening. The extended resilient means is retractable such that the plate exerts a constant force on the bag to expel fluid in a uniform flow rate.

Abstract: An alarm system (52) for a medical pump (50) associated with delivering a fluid (54) to a patient in connection with treatment of the patient is provided. The alarm system (52) comprises an alarm (60) associated with at least one treatment parameter. The alarm (60) includes a first alarm state (1) associated with a first event relating to the treatment parameter and a second alarm state (2) associated with a second event. The second alarm state (2) is discernable from the first alarm state (1), which will allow each of the events to be treated differently by a caregiver.

Abstract: A method of making a delivery device (10) for therapeutic agent, drug or vaccine is disclosed. The method includes providing a flat panel wafer, forming a plurality of reservoirs, with each reservoir defining a cavity, within the flat panel wafer, and attaching a cover layer (20) across the plurality of reservoirs. The method also includes filling the plurality of reservoirs with at least one of a therapeutic agent, drug, and vaccine to form a plurality of filled reservoirs, and providing a housing portion adjacent each of the plurality of filled reservoirs to form a composed layer. The method also includes separating the composed layer into a plurality of delivery devices, wherein each delivery device includes a reservoir. The delivery device may be suitable for self-injection use.

Abstract: A capillary fluid flow valve may include a chamber having a first boundary surface and a second boundary surface defined by a housing. The first and second boundary surfaces may be spaced apart by a gap sized to invoke capillary action between the surfaces. The first surface may be angled relative to the second surface. The chamber may have an inlet port, an outlet port, and an air vent port. The gap at the air vent port may be smaller than the gap at the outlet port and the gap at the outlet port may be smaller than the gap at the inlet port.

Abstract: A device is for the administration of injectable products with controlled flow rate, with a container (23) in the form of both a syringe and an ampoule preloaded with the injectable product, an injection port (25) and a control valve (21) for controlling the outlet rate and pressure arranged between the injectable products and the injection port (25). A device for reducing the outlet flow rate depends on the pressure increase applied during the administration of the injectable product, the administration being moderated by closing the valve (21) when the pressure exceeds a predetermined limit. A device prevents the backflow of fluids during the administration of the injectable product. The valve (21) can be positioned both in the container (23) and at an injection end (27) including the injection port (25) which is coupled to the container (23).

Abstract: An infusion device for continuous infusion of medication is disclosed, in which infusion is controlled over two separate fluid communications. The infusion is in each fluid communication controlled by restricting means and valve means, and one of the fluid communications further contains a holding device for bolus rate of infusion. The device comprises a flow regulating device comprising a passage defined by at least a first element and a second element, wherein at least one of the first and second element is a primary deformable element adapted to be elastically deformed so as to change the cross sectional area of the passage. Furthermore the device comprises a container for storage and supply of a medication in fluid form, said container comprising a first and a second chamber being arranged relatively to each other so that when volume of the first chamber increases the volume of the second chamber decreases.