Infrared, Visible Light, Or Ultraviolet Radiation Directed On Or Through Body Or Constituent Released Therefrom Patents (Class 600/310)
  • Patent number: 10070972
    Abstract: A method for intraoperatively measuring joint contact mechanics of a patient's joint is provided. The method includes inserting a sensor between first and second bones of a joint. Then a predetermined force is applied to one of the first and second bones. Afterwards, contact mechanics such as, contact stresses, contact areas and/or forces are measured between the first and second bones in response to the applied predetermined force.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: September 11, 2018
    Assignee: Hospital for Special Surgery
    Inventors: Suzanne Maher, Scott Rodeo, Russell Warren, Hongsheng Wang, Mario Lustri
  • Patent number: 10054486
    Abstract: Components resolved in time by a separator accumulate in a sample cell and are analyzed by electromagnetic radiation-based spectroscopic techniques. The sample cell can be configured for multiple path absorption and can be heated. The separator can be a gas chromatograph or another suitable device, for example a distillation-based separator. The method and system described herein can include other mechanical elements, controls, procedures for handling background and sample data, protocols for species identification and/or quantification, automation, computer interfaces, algorithms, software or other features.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: August 21, 2018
    Assignee: MLS ACQ, Inc
    Inventors: Martin L. Spartz, Anthony S. Bonanno, Peter P. Behnke
  • Patent number: 10048210
    Abstract: With a spectroscopic analysis method of the present invention, by performing principal component analysis on optical spectra measured at individual positions of a specimen, principal components of a plurality of orders that constitute the individual optical spectra are calculated; for the individual orders, principal-component images in which values thereof are principal-component scores of the individual principal components corresponding to the positions are created; distribution patterns of the principal-component scores are identified in the individual principal-component images; the morphology of the specimen is identified in a morphological image in which the specimen is captured; the principal-component images that have principal-component-score distribution patterns correlated with the morphology of the specimen are identified; and the individual optical spectra are reconstructed by using the principal components of orders corresponding to the orders of the identified principal-component images.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: August 14, 2018
    Inventors: Akira Sato, Shinichi Takimoto
  • Patent number: 10045722
    Abstract: An optical device is used to monitor an implant embedded in the tissue of a mammal (e.g., under the skin). The implant receives excitation light from the optical device and emits light that is detected by the optical device, including an analyte-dependent optical signal. Scatter and absorption properties of tissue change over time due to changes in hydration, blood perfusion and oxygenation. The optical device has an arrangement of light sources, filters and detectors to transmit excitation light within excitation wavelength ranges and to measure emitted light within detection wavelengths. Changes in scattering and absorption of light in the tissue, such as diffuse reflectance, are monitored. The light sources, filters and detectors may also be used to monitor autofluorescence in the tissue to correct autofluorescence background.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: August 14, 2018
    Assignee: Profusa, Inc.
    Inventors: Gregory J. Kintz, William McMillan, Natalie Wisniewski
  • Patent number: 10012617
    Abstract: A photoacoustic apparatus disclosed in the present specification includes: an acoustic wave transmission unit configured to transmit a transmission acoustic wave to a specific area; a control unit configured to control a transmission waveform of the transmission acoustic wave transmitted from the acoustic wave transmission unit; a light source configured to generate light emitted to an area including the specific area when the acoustic wave reaches the specific area; an acoustic wave reception unit configured to receive the acoustic wave and to output a time-series received signal; and a signal processing unit configured to acquire optical property information based on the time-series received signal, wherein the control unit controls the transmission waveform in such a manner that amplitude of a photoacoustic wave generated in the specific area is reduced by the transmission acoustic wave transmitted from the acoustic wave transmission unit.
    Type: Grant
    Filed: October 1, 2014
    Date of Patent: July 3, 2018
    Assignee: Canon Kabushiki Kaisha
    Inventor: Hiroshi Abe
  • Patent number: 10006810
    Abstract: A semiconductor sensor system, in particular a bolometer, includes a substrate, an electrode supported by the substrate, an absorber spaced apart from the substrate, a voltage source, and a current source. The electrode can include a mirror, or the system may include a mirror separate from the electrode. Radiation absorption efficiency of the absorber is based on a minimum gap distance between the absorber and mirror. The current source applies a DC current across the absorber structure to produce a signal indicative of radiation absorbed by the absorber structure. The voltage source powers the electrode to produce a modulated electrostatic field acting on the absorber to modulate the minimum gap distance. The electrostatic field includes a DC component to adjust the absorption efficiency, and an AC component that cyclically drives the absorber to negatively interfere with noise in the signal.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: June 26, 2018
    Assignee: Robert Bosch GmbH
    Inventors: Thomas Rocznik, Fabian Purkl, Gary O'Brien, Ando Feyh, Bongsang Kim, Ashwin Samarao, Gary Yama
  • Patent number: 10004456
    Abstract: The invention provides an intelligent dental ornament and a method of using the same, the intelligent dental ornament comprising: a dental ornament body with a cavity, a tester located within the cavity and for detecting a physiological parameter, a battery used by the tester, and a trigger switch for triggering the tester to start test; the dental ornament body is further provided with a through-hole for at least one pipette of the tester stretching out of the dental ornament body, and a sealing cover for sealing the through-hole. When the trigger switch activates the tester, the sealing cover is opened, and the pipette of the tester stretches out of the dental ornament body through the through-hole to obtain the saliva of the subject, and the physiology parameter in the saliva is detected, and the detection result is sent to an external device in communication with the tester.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: June 26, 2018
    Inventor: Zongmei Mu
  • Patent number: 9999711
    Abstract: Disclosed herein are systems and methods for providing reduced or negative pressure, and more particularly cyclical reduced pressure, to treat a wound. The system can include a wound dressing, a fluid collection container, a suction source, filters, and conduits. In addition, the system can include a control device and sensors. The sensors may be configured to monitor certain physiological conditions of a patient such as temperature, pressure, blood flow, blood oxygen saturation, pulse, cardiac cycle, and the like. Application of cyclical reduced pressure between two or more values below atmospheric pressure may be synchronized with the physiological conditions monitored by the sensors. Certain embodiments of the system utilize an air reservoir and one or more valves and pressure sensors or gauges to allow for rapid cycling of the level of reduced pressure within the wound dressing between two or more reduced pressure values.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: June 19, 2018
    Assignees: BlueSky Medical Group Inc., Smith & Nephew PLC
    Inventors: Richard Scott Weston, Edward Yerbury Hartwell
  • Patent number: 9993157
    Abstract: An optical measuring system comprises a control device and an optical meter. The optical meter comprises a first case, a first controller for controlling light emitters for irradiating a patient with light and light receivers for receiving light from the patient to obtain measurement data regarding a cerebral activity, and a first transmitter and receiver for transmitting the measurement data to the control device. The control device comprises a second case removably attached to the first case, a display and input device on a surface of the second case, a second transmitter and receiver for receiving the measurement data from the optical meter, and a second controller for controlling the display and input device to display the measurement data from the optical meter. The second case can be attached on a top face of the first case when the first case is placed on a table.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: June 12, 2018
    Inventors: Akihiro Ishikawa, Yoshihiro Inoue, Takashi Amita, Satoru Kohno, Haruhide Udagawa, Yoshinori Masuda
  • Patent number: 9993201
    Abstract: A wearable device includes a main body, and a strap connected to the main body, the strap being configured to be flexible. The wearable device further includes a light source disposed in the strap, the light source being configured to emit light onto a surface of a user. The wearable device further includes a spectrum portion disposed in the main body, and an optical waveguide disposed in the strap, the optical waveguide being configured to receive the emitted light traveling into and out from the surface, and transmit the received light to the spectrum portion. The wearable device further includes a detector disposed in the main body, the detector being configured to detect the transmitted light dispersing through the spectrum portion.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: June 12, 2018
    Inventor: Sang kyu Kim
  • Patent number: 9980667
    Abstract: A sensor cover according to embodiments of the disclosure is capable of being used with a non-invasive physiological sensor, such as a pulse oximetry sensor. Certain embodiments of the sensor cover reduce or eliminate false readings from the sensor when the sensor is not in use, for example, by blocking a light detecting component of a pulse oximeter sensor when the pulse oximeter sensor is active but not in use. Further, embodiments of the sensor cover can prevent damage to the sensor. Additionally, embodiments of the sensor cover prevent contamination of the sensor.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: May 29, 2018
    Inventors: Abraham Mazda Kiani, Massi Joe E. Kiani
  • Patent number: 9986353
    Abstract: An electronic device may be coupled to an accessory such as a pair of earphones. The earphones may have ear presence sensor structures that determine whether or not the ears of a user are present in the vicinity of the earphones. The earphones may contain first and second speakers. When both the first and second speakers are located in the ears of the user, the electronic device may perform functions such as playing audio content. When one of the speakers has been removed from the ears of the user while the other of the speakers remains in the ears of the user, the electronic device can take actions such as pausing the playback of audio content, switching from stereo to monophonic playback, or stopping the playback of content. Suitable actions such as increasing audio drive strength may be taken when both speakers have been removed from the ears.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: May 29, 2018
    Assignee: Apple Inc.
    Inventor: Paul G. Puskarich
  • Patent number: 9974439
    Abstract: A photoacoustic imaging method is provided that can prevent the surface of the subject from appearing in an image when a part to be observed at a position deeper than the surface of the subject is imaged. The photoacoustic imaging device includes a unit for outputting pulsed light toward the subject, and generating photoacoustic data by detecting photoacoustic waves emitted from the subject exposed to the light. The photoacoustic imaging device also includes a region detection unit that detects a near-surface region of the subject based on the photoacoustic wave detection signals, and a correcting unit that attenuates (which encompasses removing) information of the near-surface region found by the region detection unit when the part to be observed is displayed.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: May 22, 2018
    Assignee: FUJIFILM Corporation
    Inventors: Kazuhiro Hirota, Kazuhiro Tsujita
  • Patent number: 9976904
    Abstract: In one aspect, an apparatus includes a first light source that applies first light having a first wavelength as a center wavelength to an object, a second light source that applies second light having a second wavelength as a center wavelength longer than the first wavelength to the object, an optical filter that includes first and second regions and that transmits third light produced by the first and second light each passed through or reflected by the object, first and second optical detectors that determine first and second amounts, respectively, of the third light passed through the first and second regions. The transmission ranges of spectral transmission curves of the first and second regions are located between the first wavelength and the second wavelength. The spectral transmission curve of the first region has a width at half maximum different from that of the spectral transmission curve of the second region.
    Type: Grant
    Filed: July 9, 2016
    Date of Patent: May 22, 2018
    Inventor: Seiji Nishiwaki
  • Patent number: 9946931
    Abstract: An approach for land cover classification, seasonal and yearly change detection and monitoring, and identification of changes in man-made features may use a clustering of sparse approximations (CoSA) on sparse representations in learned dictionaries. A Hebbian learning rule may be used to build multispectral or hyperspectral, multiresolution dictionaries that are adapted to regional satellite image data. Sparse image representations of pixel patches over the learned dictionaries may be used to perform unsupervised k-means clustering into land cover categories. The clustering process behaves as a classifier in detecting real variability. This approach may combine spectral and spatial textural characteristics to detect geologic, vegetative, hydrologic, and man-made features, as well as changes in these features over time.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: April 17, 2018
    Assignee: Los Alamos National Security, LLC
    Inventor: Daniela Irina Moody
  • Patent number: 9940710
    Abstract: A biological information detection device includes first and second light sources, an image capturing system, and an arithmetic circuit. The first and second light sources project, onto a living body, at least one first dot formed by first light and at least one second dot formed by second light, respectively. The image capturing system includes first photodetector cells and second photodetector cells. The image capturing system generates and outputs a first image signal and a second image signal. The arithmetic circuit generates information concerning the living body, by using the first and second image signals. The first light includes fifth light. The second light includes sixth light. Each of the fifth light and the sixth light has a wavelength in a range from 650 nm to 950 nm. The wavelength of the sixth light is longer than that of the fifth light by 50 nm or more.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: April 10, 2018
    Inventor: Hisashi Watanabe
  • Patent number: 9924874
    Abstract: A measurement device according to the present disclosure includes a light source for emitting measurement light which is used for measuring an in vivo component present in a living body and belongs to a predetermined wavelength band toward the living body, a detection unit in which a plurality of sensors is regularly arranged in a predetermined arrangement and which detects the measurement light emitted from the light source and passing through the living body with the plurality of sensors, and an analysis unit which analyzes an amount of the in vivo component based on an amount of light attenuated depending on an optical distance from the light source by use of a detection result detected by the detection unit.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: March 27, 2018
    Assignee: Sony Corporation
    Inventor: Hideo Sato
  • Patent number: 9907494
    Abstract: A near infrared spectrometer and method for wavelength and path length correction are disclosed. The spectrometer includes a number of photodiodes that transmit broadband near infrared measurement light into the tissue and at least one broadband detector which measures the light signal transmitted through the tissue. A processor estimates chromophore concentrations through a comparison of measured light attenuation and modeled light attenuation. The light attenuation model utilizes a light path length distribution derived from a Monte Carlo model and accounts for the spectral shape of the light source as a function of temperature.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: March 6, 2018
    Assignee: Hutchinson Technology Incorporated
    Inventors: Bryan J. Scheele, Nicholas H. Finstrom, Roger W. Schmitz
  • Patent number: 9903709
    Abstract: An insertion portion detection device provided with a light source unit which emits measuring beam to an outer circumferential surface of a cylindrical shape of an insertion portion to be inserted into an insertion target and to be a detection target, an optical pattern detection unit which receives reflected light from the outer circumferential surface and which sequentially acquires image data in a predetermined range of the outer circumferential surface including given optical patterns so that at least some of the optical patterns correspond to the image data, and a displacement amount calculation unit which detects a corresponding optical pattern from the image data and calculates at least one of an insertion amount of the insertion portion and an amount of rotation around the central axis of the cylindrical shape.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: February 27, 2018
    Inventors: Ryo Tojo, Eiji Yamamoto, Jun Hane
  • Patent number: 9895090
    Abstract: A system includes a mobile computing device, a sleeve, a contact surface, a sensor module, and a telemetry module. The mobile computing device has a first processor within a housing. The sleeve has an internal surface configured to fit the housing. The contact surface is disposed on an external surface of the sleeve. The sensor module is coupled to the contact surface and is configured to generate an electrical signal corresponding to a measured physiological parameter associated with tissue at the contact surface. The telemetry module is coupled to the sensor module and is configured to communicate data corresponding to the electrical signal to the mobile computing device.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: February 20, 2018
    Assignee: Nonin Medical, Inc.
    Inventors: Timothy L. Johnson, Bryant Austin Jones, Christopher Holland
  • Patent number: 9892334
    Abstract: The invention teaches a multiple reference optical coherence tomography scanner that provides a subdermal fingerprint scan, covers an area of approximately 16 mm-17 mm×10 mm in less than a second, and fits into a slim profile of less than 6 mm in thickness, thereby fitting within the slim consumer electronics such as the iPhone and similar consumer electronics. Various embodiments are taught.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: February 13, 2018
    Inventor: Joshua Noel Hogan
  • Patent number: 9884183
    Abstract: An active bipolar cardiac electrical lead includes a distal electrode (108), an intermediate connection mount (109), a ring electrode (103), and a tip housing (110). The intermediate connection mount (109) defines a proximal fitting (370) and a distal fitting (374). The ring electrode (103) has an exposed section (356) that sleeves over and engages the proximal fitting (370) of the intermediate connection mount (109) with a snap-fit connection. The intermediate connection mount (109) may connect the ring electrode (103) to the tip housing (110) and provide electrical insulation between the ring electrode (103) and the distal electrode (108).
    Type: Grant
    Filed: December 31, 2012
    Date of Patent: February 6, 2018
    Inventors: Grace Ying Yang Jang, Zhijun Cheng
  • Patent number: 9872621
    Abstract: An embodiment includes a functional near infrared (fNIR) system comprising: first, second, and third light emitting diodes (LED) and a photo detector; and at least one storage medium having instructions stored thereon for causing the system to: (a) emit photo energy at first, second, and third wavelengths from the first, second, and third LEDs during first and second time periods, (b) determine first, second, and third optical density changes and changes in first and second chromophore concentrations based on the emitted photo energy; and (c) determine and fit first, second, and third absorption values to a first absorption spectra curve based on the determined changes in first and second chromophore concentrations. Other embodiments are described herein.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: January 23, 2018
    Assignee: Intel Corporation
    Inventors: Maynard C. Falconer, Willem M. Beltman
  • Patent number: 9861303
    Abstract: An exemplary apparatus for measuring the concentration of a test substance in an organism disclosed herein includes: a measurement system which measures first and second concentrations that are concentrations of the test substance at positions A and B, respectively, where the positions A and B are located inside of the organism but outside of the blood vessel of the organism, and the position B is located more distant from the blood vessel than the position A is; and a decision circuit which determines, based on the first and second concentrations, whether or not an equilibrium has been established yet between a concentration of the test substance inside of the blood vessel and a concentration of the test substance measured at a position inside of the organism but outside of the blood vessel of the organism.
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: January 9, 2018
    Assignee: Panasonic Intellectual Property Management Co., Ltd.
    Inventors: Tatsurou Kawamura, Yasuaki Okumura, Masaru Minamiguchi, Masahiko Shioi
  • Patent number: 9861315
    Abstract: The present invention pertains to a functional patch to be affixed to the skin, with the aim of measuring metabolic disruptions to organs, and general organ functions, of kidneys, liver, heart, pancreas and muscles (lactate), for example—more particularly it concerns the measurement of the glomerular filtration rate (GFR)—and also to a method for producing a functional patch of this kind.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: January 9, 2018
    Assignee: Lohmann GMBH & Co. KG
    Inventors: Norbert Gretz, Daniel Schock-Kusch, Michael Herbertz, Ralf Nittenwilm
  • Patent number: 9848787
    Abstract: Methods and apparatus for measuring perfusion using transmission laser speckle imaging are provided. The apparatus comprises a coherent light source and a detector configured to measure transmitted light associated with an unfocused image at one or more locations. The coherent light source and detector are positioned in a transmission geometry. The apparatus further comprises means for securing the coherent light source and the detector to the tissue sample in a fixed transmission geometry relative to the tissue sample. The apparatus may further comprise at least one processor to receive information from the detector and process detected variations in transmitted light intensity to determine a single metric of perfusion. The method may comprise the steps transilluminating a tissue sample with coherent light, recording spatial and/or temporal variations in the transmitted light signal, determining speckle contrast value(s), and computing a metric of perfusion.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: December 26, 2017
    Assignee: Laser Associated Sciences, Inc.
    Inventors: Sean Michael White, Bruce Yee Yang, Tyler Bywaters Rice
  • Patent number: 9833180
    Abstract: Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: December 5, 2017
    Inventors: Walter J. Shakespeare, William Henry Bennett, Jason T. Iceman, Howard P. Apple, Phillip William Wallace, Matthew J. Schurman
  • Patent number: 9820656
    Abstract: The invention pertains to the establishment, implementation and management of a personalized information system pertinent to a user's general health, wellness and/or sport performance. Disclosed is a system capable of transcutaneous measurement of a subject including at least one light source, at least one light detector, and at least one component for generating or storing at least one value of VC02 or at least one value of V02 from the detected signal. Further, disclosed is a portable device for analyzing the composition of the respired gasses of a subject including at least one air flow conduit through which the subject can inspire or expire air through the body of the device, at least one sampling portal, an oxygen sensor, and at least one flow sensor. A dual-battery system is also provided by which an uninterrupted power supply can be provided for electronic components.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: November 21, 2017
    Assignee: LifeQ Global Limited
    Inventor: Laurence Richard Olivier
  • Patent number: 9808204
    Abstract: Methods and apparatus for qualifying and quantifying excitation-dependent physiological information extracted from wearable sensors in the midst of interference from unwanted sources are provided. An organism is interrogated with at least one excitation energy, energy response signals from two or more distinct physiological regions are sensed, and these signals are processed to generate an extracted signal. The extracted signal is compared with a physiological model to qualify and/or quantify a physiological property. Additionally, important physiological information can be qualified and quantified by comparing the excitation wavelength-dependent response, measured via wearable sensors, with a physiological model.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: November 7, 2017
    Assignee: Valencell, Inc.
    Inventors: Steven Francis LeBoeuf, Jesse Berkley Tucker, Michael Edward Aumer
  • Patent number: 9801577
    Abstract: Methods, devices, systems, and computer program products are provided to improve sensitivity calibration of an in vivo analyte sensor and usability of an associated analyte monitoring system. In certain embodiments, methods are provided that improve the user experience of using an analyte monitoring system. Certain embodiments of the present disclosure include features that reduce the amount of calibration or re-calibration performed by the analyte monitoring system. More specifically methods of using a suspect calibration attempt to avoid having to recalibrate by adjusting the calibration or mitigating effects of sensor signal attenuation that caused the calibration attempt to be suspect are provided. Additional features are disclosed.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: October 31, 2017
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Erwin Satrya Budiman, Gary Alan Hayter
  • Patent number: 9795329
    Abstract: A system includes a light source and a light detector. The system further includes a first optical system configured to direct a transmitted portion of light onto the detector. The first optical system is further configured to block a scattered portion of the light. The system also includes a second optical system configured to direct the transmitted and scattered portions of the light onto the detector.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: October 24, 2017
    Assignee: GlucoVista Inc.
    Inventor: Yonatan Gerlitz
  • Patent number: 9788769
    Abstract: A handheld multi-parameter measuring instrument includes: a housing having a sidewall and opposed first and second surfaces, the sidewall, the first surface and the second surface cooperatively forming a cavity; a cover attached to the sidewall and rotatably connected to the housing; the blood oxygen transducer includes a light emitting unit and a light receiving unit; the light emitting unit is configured to emit red light and infrared light alternately; the light receiving unit is configured to receive the red light and the infrared light emitted from the light emitting unit; the signal processing unit is received in the cavity of the housing and is configured to control the light emitting unit to emit the red light and the infrared light alternately; the signal processing unit is further configured to calculate oxygen saturation based on a signal received by the light receiving unit; the light emitting unit is located at a side of the cover attached to the housing, and the light receiving unit is located a
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: October 17, 2017
    Inventors: Saixin Zhou, Bing Wang, Pinbo Wang
  • Patent number: 9782080
    Abstract: An object information acquiring apparatus comprises an irradiating unit which irradiates light on an object; a holding member which includes a light-absorbing member whose optical characteristics with respect to irradiated light are known and which holds the object; a detector which detects acoustic waves generated by tissue in the object and the light-absorbing member due to light irradiation; and a computing unit which calculates optical characteristics of the tissue in the object and the light-absorbing member by using the detected acoustic waves and which corrects the optical characteristics of the tissue in the object by using the calculated optical characteristics of the light-absorbing member and the known optical characteristics.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: October 10, 2017
    Inventors: Takahiro Suita, Takuro Miyasato
  • Patent number: 9776016
    Abstract: A system and method to selectively illuminate (part of) an infant during phototherapy uses an array of collimators and a set of light sources to control impingement of electromagnetic radiation on the infant.
    Type: Grant
    Filed: September 2, 2013
    Date of Patent: October 3, 2017
    Assignee: Koninklijke Philips N.V.
    Inventors: Vishnu Vardhan Makkapati, Anil Shivram Raiker, Shrutin Ulman
  • Patent number: 9778111
    Abstract: The invention is a method for estimating a cardiac frequency via the detection of radiation backscattered or transmitted by a bodily zone. The part is illuminated, simultaneously or successively, by light radiation extending over a first spectral band and a second spectral band. A photodetector detects radiation emitted by the bodily zone under the effect of its illumination, in each of the spectral bands. A first detection function and a second detection function are formed from the radiation detected in each spectral band, respectively. The method allows the cardiac frequency to be determined via the determination of characteristic instants that are identified from the first detection function and the second detection function simultaneously.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: October 3, 2017
    Assignee: Commissariat A L'Energie Atomique et aux Energies Alternatives
    Inventors: Sylvain Stanchina, Anne Koenig
  • Patent number: 9775543
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: October 3, 2017
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Steve Masterson, John Michael Dobbles, Michael Robert Mensinger, Sean Saint, Apurv Ullas Kamath
  • Patent number: 9770198
    Abstract: A sensor which is adapted to attach to a head of a subject includes a first fastener that includes a first end portion and a second end portion and extends into an arc-shape, a first coupling portion that is disposed on an inner circumference side of the first fastener, a second fastener that has a first through hole and a second through hole, a second coupling portion that is disposed on a first side of the second fastener, and attachable to and detachable from the first coupling portion, a light emitter that is disposed on the first side of the second fastener, and opposed to the first through hole, and a light detector that is disposed on the first side of the second fastener, and opposed to the second through hole.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: September 26, 2017
    Inventor: Hideki Fujisaki
  • Patent number: 9766126
    Abstract: An analyzer apparatus and method of use thereof is described to dynamically irradiate a sample with incident light where the incident light is varied in time in terms of any of: position, radial position relative to a point of the skin of a subject, solid angle, incident angle, depth of focus, energy, and/or intensity. For example, the incident light is varied in radial position as a function of time relative to one or more of a sample site, a point on skin of the subject, a detection optic, and/or a sample volume observed by a detection system. The radially varied incident light is used to enhance and/or vary light probing the epidermis, the dermis, and/or the subcutaneous fat of the subject or of a group of subjects.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: September 19, 2017
    Assignee: Zyomed Corp.
    Inventors: Sandeep Gulati, Thomas George, Timothy L. Ruchti, Alan Abul-Haj, Kevin H. Hazen
  • Patent number: 9760832
    Abstract: A method and apparatus for predicting based on multi-source heterogeneous data. The method comprises: acquiring, with regard to an event of a set type, at least two types of historical data that can reflect an event result; establishing a joint likelihood model of attribute data of the event of the set type and the historical data; determining an optimal estimation of the attribute data according to a maximum posterior principle; and determining, based on a probability distribution associated with the attribute data in the joint likelihood model, a parameter in the probability distribution as a prediction result of a predicted event of the set type. Some embodiments use a hierarchical model to introduce data of different sources into different data layers, unify heterogeneous data in a joint likelihood model to perform analysis, and obtain a more accurate, instant and stable prediction result through effective fusion.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: September 12, 2017
    Inventors: Qing Wang, Wei Hu, Zhiyong Shen
  • Patent number: 9743869
    Abstract: An optical isolation element is provided on an optical sensor comprising a light source, at least one photodetector, and indicator material that emits light that is detected by the photodetector when optically excited by the light source. The optical isolation element limits the optical paths by which light may be transmitted by the light source, thereby limiting exposure of the excitation light source to regions of interest. The optical isolation element also limits the optical paths by which light may be transmitted to the photodetector, thereby limiting exposure of the photodetector to light from extraneous sources.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: August 29, 2017
    Assignee: Senseonics, Incorporated
    Inventor: Allan Caban
  • Patent number: 9739716
    Abstract: A method for regulating the relative position of an analyte of a sample (16) in relation to a light beam (F) includes the illumination of the analyte of the sample (16) with the light beam (F), capturing by an imaging device (38) a transmission image of the beams scattered by the analyte of the sample (16) in order to establish a diffraction pattern, and modifying the relative position of the analyte of the sample (16) in relation to the light beam (F) according to at least one property of the diffraction pattern.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: August 22, 2017
    Inventors: Samy Strola, Cedric Allier, Mathieu Dupoy, Emmanuelle Schultz
  • Patent number: 9737246
    Abstract: An apparatus and a program are provided which are capable of simultaneously measuring, evaluating, imaging and displaying the biological function of sites with different biological functions, such as the brain and the muscle, different parts of the brain or different muscle locations, using near-infrared spectroscopy. In an apparatus for evaluating biological function K, physiological indices, including parameters derived from changes in deoxyhemoglobin concentration and changes in oxyhemoglobin concentration, are calculated by a calculating part of a controller. To measure simultaneously, evaluate, image and display the biological functions of sites with different biological function, such as the brain and the muscle, different parts of the brain or different muscle locations, these physiological indices from different sites of the living body are adjusted in such a way that they can be compared with each other by the calculating part and displayed by a display part.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: August 22, 2017
    Inventor: Toshinori Kato
  • Patent number: 9724022
    Abstract: An apparatus for non-invasive glucose monitoring includes a light source for emitting at least one ray of light; a first beam splitter, a set of photo detectors for measuring optical rotatory distribution (ORD) information and absorption energy information; a reference component receiving the light from the first beam splitter, and the light reflected by the reference component being transmitted to the set of photo detectors by the first beam splitter, wherein the light emitted from the light source is transmitted to the set of photo detectors by the first beam splitter and the eyeball to form a first optical path, the light emitted from the light source is transmitted to the set of photo detectors by the first beam splitter and the reference component to form a second optical path; and a processing unit receiving and processing the ORD information and the absorption energy information to obtain a glucose information.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: August 8, 2017
    Assignee: Taiwan Biophotonic Corporation
    Inventors: Yu-Tang Li, Chang-Sheng Chu, Chih-Hsun Fan, Shuang-Chao Chung, Ming-Chia Li, Jyh-Chern Chen, Kuo-Tung Tiao
  • Patent number: 9721141
    Abstract: A wrist-worn apparatus control with fingerprint data includes a physical activity-related measurement sensor interface, a fingerprint sensor, one or more processors, and one or more memories including computer program code. The one or more memories and the computer program code are configured to, with the one or more processors, cause the apparatus at least to receive fingerprint data from a user with the fingerprint sensor, identify the fingerprint data as matching with one finger of the user on the basis of a comparison between the fingerprint data and reference data of a plurality of fingers of the user stored in the memory, and select a function of a physical activity-related measurement on the basis of the identified finger.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: August 1, 2017
    Assignee: POLAR ELECTRO OY
    Inventor: Pertti Puolakanaho
  • Patent number: 9717464
    Abstract: Various embodiments of methods and systems for continuous transdermal monitoring (“CTM”) are disclosed. One exemplary method for CTM begins by monitoring an output signal from an accelerometer. The accelerometer output signal may indicate acceleration and deceleration of a body part of a user, such as the user's wrist. Based on the accelerometer output signal, it may be determined that the body part of the user has decelerated to a minimum, e.g., substantially zero. With a determination that the body part has decelerated to the minimum, e.g., substantially zero, or has not accelerated beyond the minimum, e.g., substantially zero, the method may determine a reading from a pulse oximeter associated with the accelerometer. Advantageously, the pulse oximetry reading, or a reading from other sensors associated with the accelerometer, may be optimally accurate as motion artifact may be minimized. The pulse oximetry reading may be recorded for later query and/or rendered for the benefit of the user.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: August 1, 2017
    Inventors: James Tyler Frix, Andrew Johnson, James Mitchell Frix, Robert Andrew Taylor
  • Patent number: 9714900
    Abstract: A system and optimization algorithm for determining the preferred operational wavelengths of a device configured for measurement of molecular analytes in a sample. Operational wavelengths are determined by solving a system of equations linking empirically defined functions representative of these analytes, spectrally dependent coefficients corresponding to these analytes, path lengths traversed by waves probing the analytes at wavelengths corresponding to the absorption level described by the functions representative of these analytes, and, optionally, a cost-function taking into account at least one of spectral separation between the operational wavelengths, manufacturability of wave source(s) producing wave(s) at operational wavelength(s), and the noise factor associated with the operation of such wave source(s).
    Type: Grant
    Filed: April 29, 2013
    Date of Patent: July 25, 2017
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Clifton R. Haider, Barry K. Gilbert, Gary S. Delp
  • Patent number: 9713428
    Abstract: Systems and methods that enable physiological monitoring with a mobile communication device and that allow detection of motion artifacts so that the results reported are of acceptable quality are disclosed.
    Type: Grant
    Filed: January 20, 2012
    Date of Patent: July 25, 2017
    Assignee: Worcester Polytechnic Institute
    Inventors: Ki H. Chon, Jinseok Lee, Nandakumar Selvaraj
  • Patent number: 9709588
    Abstract: An automatic analyzer with high processing capacity is capable of immediately measuring an emergency specimen rack. The automatic analyzer includes a conveying line for conveying a specimen rack, and an analysis unit which has a dispensing line in which a plurality of specimen racks are arranged for waiting until sample dispensing, and a sampling area for dispensing the sample to the analysis unit. A rack save area is provided in the dispensing line and at a position adjacent to the upstream side of the sampling area. When a specimen rack exists in the sampling area at the time of measuring an emergency specimen rack, a controller moves the specimen rack to the save area and positions the emergency specimen rack to be moved from a downstream side of the sampling area to the sampling area.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: July 18, 2017
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Akihisa Makino, Mitsuhiro Hishinuma, Toshiyuki Shimamori, Masato Ishizawa
  • Patent number: 9700212
    Abstract: The present invention provides a method of detecting nerves, including: step 1 of irradiating a sample with excitation light; step 2 of detecting Raman scattering light from the sample; step 3 of calculating an intensity ratio of a wave number within a specific range of the Raman scattering light detected in the step 2 or extracting a feature of the intensity ratio and subjecting the feature to multivariate analysis and/or statistical analysis; and step 4 of specifically displaying nerves containing unmyelinated nerves, using as an index the intensity ratio or a result from the multivariate analysis and/or the statistical analysis.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: July 11, 2017
    Inventors: Tetsuro Takamatsu, Takeo Minamikawa, Yoshinori Harada
  • Patent number: 9693719
    Abstract: A pulse oximetry sensor includes reusable and disposable elements. To assemble the sensor, members of the reusable element are mated with assembly mechanisms of the disposable element. The assembled sensor provides independent movement between the reusable and disposable elements.
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: July 4, 2017
    Inventors: Ammar Al-Ali, Yassir Abdul-Hafiz