Abstract: Embodiments of the present disclosure relate to techniques for neuromodulation delivery. Based on image data acquired from the subject, control parameters controlling energy application of neuromodulating energy may be dynamically changed during the course of the delivery to maintain desired characteristics of the neuromodulating energy. For example, the beam of the neuromodulating energy may be dynamically adjusted to account for movement of an organ during breathing. In another embodiment, a desired region of interest is identified within the subject based on a trained neural network and the acquired image data.

Abstract: Apparatus and associated methods relate to a connected pill dispenser configured to treat a patient's illness with a robotic arm adapted to deliver a prescribed medication dose to a patient in their home, analyze the patient's response to the dose based on various sensor inputs, automatically determine whether the patient took the medicine and send the provider the result of providing the medication dose to the patient. In an illustrative example, the patient may be a chronic, acute, or terminal illness patient. The medication dose may be, for example, a medication prescribed by a doctor to be taken in a specific amount at specific times. In some embodiments, the connected pill dispenser may automatically notify the patient when a medication dose is due.

Abstract: An apparatus for assessing user frailty is disclosed. In embodiments, the apparatus includes a housing that defines (or is defined by) a body and a handle coupled to the body. The apparatus includes a force sensor at least partially disposed within the handle. The apparatus further includes an inertial sensor at least partially disposed within the housing. The apparatus may further include a user interface device disposed within a cavity of the body. The user interface device may be coupled to the force sensor and the inertial sensor via one or more signal paths. In embodiments, the user interface device includes a controller with a touchscreen coupled to the controller.

Abstract: Methods and apparatus provide communications among respiratory therapy device (“TD”), server and intermediary (e.g., a control device (“CTLD”) for the therapy device) to improve security. More secure communication channel(s) may be established using shared secrets derived with different channels. The communications may include transmitting therapy data from TD to server for authentication. The CTLD may receive the data and a nonce from a server. The CTLD receives from the TD a signing key dependent on the nonce and a secret shared by TD and server. The CTLD generates an authorisation code with received therapy data and the key for authentication of the data by the server upon its receipt of the code and data. The server computes (1) a key from the nonce and the secret known to TD, and (2) another authorisation code from received therapy data and the key. Data authentication may involve comparing received and computed codes.

Abstract: Machine learning systems and methods are disclosed for prediction of wound healing, such as for diabetic foot ulcers or other wounds, and for assessment implementations such as segmentation of images into wound regions and non-wound regions. Systems for assessing or predicting wound healing can include a light detection element configured to collect light of at least a first wavelength reflected from a tissue region including a wound, and one or more processors configured to generate an image based on a signal from the light detection element having pixels depicting the tissue region, determine reflectance intensity values for at least a subset of the pixels, determine one or more quantitative features of the subset of the plurality of pixels based on the reflectance intensity values, and generate a predicted or assessed healing parameter associated with the wound over a predetermined time interval.

Abstract: Improved risk categorization is provided for clinical decision support and forecasting future health care spend. A risk index is provided that improves on other risk stratification models by synthesizing electronic medical records and health questionnaires with an individual patient's claim histories. Machine learning algorithms catalogue patients into distinct group clusters, based on risk which may be associated with annual health care spending, thereby enabling administrators to forecast future health care spending on the individual and population level.

Abstract: Orthopedic device or implants are provided, comprising an orthopedic device or implant and a sensor.

Abstract: A system for generating a longevity element and an instruction set for a longevity element plan, the system including at least a computing device, wherein the computing device is designed and configured to receive, from a user, at least an element of user-reported data, determine, using the at least an element of user-reported data and a first machine-learning process, a longevity element, calculate, using a longevity element and at least a second element of data, a compensatory supplement, and generate, using the at least an element of user-reported data and at least a longevity element, an instruction set for a longevity element plan.

Abstract: A method for monitoring medical data is disclosed, the method being applicable to a system comprising a portable medical device, a mobile communications device, and, optionally, a medical care server. The portable medical device and the mobile communications device each comprise at least one interface for data transfer. The method comprises a step of establishing a download link between the mobile communications device and a download server. The method comprises a step of selecting an appropriate communication software package from a plurality of communication software packages for controlling data transfer between the mobile communications device and the portable medical device from the download server. Further, the method comprises a download step for downloading communication software packages from the download server to the mobile communications device and a step of installation of the communication software package on the mobile communications device.

Abstract: Systems and methods for monitoring eyedrop usage are disclosed. Example embodiments include a system to monitor eyedrop usage. The system may include a detection and activation circuit couplable to a wireless biosensor and an eyedrop dispenser. The detection and activation circuit may include a pressure transducer that transmits a signal upon detecting a force at, or above, a threshold value. The system may also include a wireless biosensor insertable into a region of an eyelid. The wireless biosensor may include a sensor to detect the physical change and the chemical change of tears as a result of eyedrop usage. The wireless biosensor may also include a transceiver to receive the signal that activates the sensor for an activation time.

Abstract: A stimulation probe device including a first electrode, a stimulation module, a control module and a physical layer module. The stimulation module is configured to (i) wirelessly receive a payload signal from a console interface module or a nerve integrity monitoring device, and (ii) supply a voltage or an amount of current to the first electrode to stimulate a nerve or a muscle in a patient. The control module is configured to generate a parameter signal indicating the voltage or the amount of current supplied to the electrode. The physical layer module is configured to (i) upconvert the parameter signal to a first radio frequency signal, and (ii) wirelessly transmit the first radio frequency signal from the stimulation probe to the console interface module or the nerve integrity monitoring device.

Abstract: A system for estimating maximum heart rate and maximal oxygen uptake from submaximal exercise intensities can include an exercise intensity monitor, a cardiopulmonary monitor, and one or more computers. The computers can be configured, by virtue of appropriate programming, to receive submaximal exercise intensity data from the exercise intensity monitor and submaximal cardiopulmonary data from the cardiopulmonary monitor while a user, who coupled to the exercise intensity monitor and the cardiopulmonary monitor, is performing an exercise at a submaximal exercise intensity. The one or more computers then determine a heuristic estimate of a maximal cardiopulmonary state of the user based on the submaximal exercise intensity data and the submaximal cardiopulmonary data.

Abstract: A laser monitoring system designed to prevent accidental falls of people who are at high risk of falling when they try to get up from a chair, commode, or bed. The system includes a first unit providing a circuit board, a laser emitting device, an alignment indicator, a control button, a communicator, an alarm speaker, an electrical port, and an electrical housing that retains all of the above. The system also includes a second unit providing a circuit board, a laser receiving device, an alignment indicator, and receiver which are all retained inside of an electrical housing. The first unit and second unit form a laser net alarm system that when interrupted provides an audible alarm requesting that the patient wait for medical attention, while at the same time may notify the care giver that their patient is trying to get up unassisted by sending an electronic message to the care giver's electronic device.

Abstract: Systems and methods for monitoring patients with multiple chronic diseases are described. A system may include a health status monitor that receives diagnostic data including physiological signals sensed from a patient. The system may produce at least a first risk indication of the patient developing a first disease and a second risk indication of the patient developing a different second disease. The system may detect the first and second diseases from the physiological signals, and generate a composite health status indicator using the detections of the first and second diseases and the first and second risk indications. An alert of worsening health status may be generated if the composite detection score exceeds an alert threshold.

Abstract: Provided are a brain stimulation system, method, apparatus and storage medium based on artificial intelligence. The system includes: a plurality of brain stimulation terminals and a cloud platform. The cloud platform is configured to, with artificial intelligence algorithm especially machine learning and deep learning, generate multi-dimensional psychological big data using physiological data and psychological state evaluation parameters gotten from the plurality of brain stimulation terminals and established models of algorithm for disease diagnosis.

Abstract: System and method for generating personalized nutrition prescriptions and modifying the personalized nutrition prescriptions based on feedback. Exemplary implementations may: receive user input defining biometric information, physique goals associated with individual users, and/or other information; provide the nutrition prescriptions to the individual users based on the biometric information and the physique goals; provide the nutrition prescriptions to the individual users; obtain feedback from the individual users; modify the nutrition prescriptions based on comparison between the obtained feedback and projected progress towards the physique goals associated with the individual users; provide the modified nutrition prescriptions to the individual users; and/or other exemplary implementations.

Abstract: A system for generating an alimentary plan is disclosed. The system comprises a computing device which is configured to receive an input that includes physiological data related to a skin sample. Computing device is configured to extract a plurality of biological indicators related to disease state from the physiological data. Computing device is configured to determine a biological indicator score for each biological score for each biological indicator of the plurality of biological indicators. Computing device is configured to generate a skin disorder classifier by receiving skin disorder training data. The computing device is configured to classify, using the skin disorder classifier, the at least one biological indicator and the biological indicator score to a positive result for a skin disorder. Computing device is configured to generate an alimentary plan as a function of the positive result. A method for generating an alimentary plan is also disclosed.

Abstract: Methods and systems for presenting a proactive audiovisual query using a virtual assistant software application. The methods correspond to retrieving user experience data associated with a user profile for the virtual assistant software application, wherein the user experience data define one or more user experience events for the user profile. The methods further include retrieving subject matter domain data associated with the one or more user experience events, wherein the subject matter domain data define one or more probabilistic event effects for the one or more user experience events and determining, based on the user experience data and the subject matter domain data, one or more optimal query items, wherein the one or more optimal query items are associated with at least one of the one or more probabilistic event effects. The methods further include generating the proactive audiovisual query in accordance with the one or more optimal query items.

Abstract: A medication inventory system may include a medication tray that includes partitions defining compartments. The medication tray has a tray identifier associated therewith, and each compartment is for storing a respective medication having a radio frequency identification (RFID) tag associated therewith. The system may include an RFID tag reader, and a processor and an associated memory configured to maintain in the memory a desired respective medication within each compartment based upon the tray identifier, and cooperate with the RFID tag reader to determine the respective medication within each compartment based upon the respective RFID tag. The processor and associated memory may also be configured to determine a discrepancy between the determined medication within each compartment and the desired respective medication within each compartment, and when so generate a display notification that includes a visual indicator corresponding to each compartment determined to have the discrepancy.

Abstract: A system and method are presented in which known genetic attributes associated with a condition are used to seed the determination of additional attributes which are associated with the condition. Based on the learning, the additional attributes (genetic, behavioral, or both) provide for an increased correlation between the combined attributes and the condition. For behavioral attributes, a measure of the impact of the behavioral attribute on the risk of the condition can be transmitted to another device or system.

Abstract: Methods, devices, and systems (for outputting a case summary) receive an electronic medical record (EMR) (and generally electronic records) for the medical patient, extract medical data from the EMR, provide a list of medical problems relevant to the EMR, identifying relations between the medical problems and the medical data using a question-answering (QA) system, and output the clinical summary for the EMR. The clinical summary comprises the list of medical problems, the medical data, and the relations.

Abstract: Systems and methods can be used to provide an indication of heart function, such as an indication of mechanical function or hemodynamics of the heart, based on electrical data. For example, a method for assessing a function of the heart can include determining a time-based electrical characteristic for a plurality of points distributed across a spatial region of the heart. The plurality of points can be grouped into at least two subsets of points based on at least one of a spatial location for the plurality of points or the time-based electrical characteristics for the plurality of points. An indication of synchrony for the heart can be quantified based on relative analysis of the determined time-based electrical characteristic for each of the at least two subsets of points.

Abstract: An electrocardiogram analysis apparatus includes: an electrocardiogram signal inputting section to which electrocardiogram signals of measurement electrodes attached to a subject are input; a mistaken attachment determining section which, by using the input electrocardiogram signals, determines whether the measurement electrodes are mistakenly attached or not; an outputting section which, if it is determined that the measurement electrodes are mistakenly attached, notifies of mistaken attachment of the measurement electrodes; and an electrocardiogram data storing section which, in a case where there is an input indicative of confirmation of the notification, stores information indicating that the measurement electrodes have been checked, together with the input electrocardiogram signals, and, in a case where there is not an input indicative of confirmation of the notification, stores information indicating that the measurement electrodes have not been checked, together with the input electrocardiogram signals

Abstract: Systems and methods for planning delivery of an object via a catheter, such as transseptal delivery of a prosthetic mitral valve to a patient's heart are disclosed.

Abstract: A system includes a heat exchange catheter line assembly configured to convey working fluid circulating to and from at least one heat exchange element on an intravascular heat exchange catheter. The system also includes a heat exchange system that itself includes a processor and is configured for fluidly communicating with the heat exchange catheter line assembly to exchange heat with the working fluid. A near filed communication (NFC) member associated with the heat exchange system and an NFC element associated with the heat exchange catheter line assembly are also included. The NFC member is configured to provide the processor with a signal representative of whether the NFC member detects the NFC element.

Abstract: A system and method that identifies delayed infusion programs at an infusion pump or with a first computer and an infusion pump. The first computer receives an infusion auto-program from a remote source, transmits the infusion auto-program to the infusion pump, and sends a stale auto-program to the infusion pump. The infusion pump receives a manual infusion program, saves and executes the manual infusion program, and compares the stale auto-program to the manual infusion program to identify potential matches between the stale auto-program and the manual infusion program. The infusion pump evaluates the potential matches and determines if the potential matches are within a predefined tolerance, continues to execute the at least one manual infusion program on the infusion pump if the potential matches are within the predefined tolerance, and remotely saves differences in the manual infusion program and the at stale auto-program in a remote server for later analysis.

Abstract: A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface.

Abstract: A wheelchair system includes a wheelchair including a plurality of force sensors including at least three force sensors. A rigid seat pan is placed in contact with each the plurality of force sensors at a different position on the rigid seat pan so that the rigid seat pan does not contact the frame and forces on the rigid seat pan are transferred to the plurality of force sensors. Each of the plurality of force sensors is in communicative connection with a processor system. A memory system is in communicative connection and an interface system is in connection with the processor system and a user interface system in communicative connection with the processor system. Instructions stored on the memory system are executable by the processor system to determine a value of a variable related to a distribution of force on the rigid seat pan over time.

Abstract: Systems and methods for identifying potential ablation sites using electrical parameter data are provided. A method includes geometrically isolating an arrhythmogenic substrate in a three-dimensional geometry. The method further includes generating a first cumulative map from a first dataset including electrical parameter data for each vertex in the isolated arrhythmogenic substrate, and generating a second cumulative map from a second dataset including additional data for each vertex. The method further includes generating a third cumulative map from the first and second cumulative maps, and displaying the third cumulative map on the three-dimensional geometry to facilitate identifying potential ablation sites.

Abstract: A heart rate sensor within a hearing assistance device may provide heart rate information or other sensor data, which may be used to determine how well the hearing assistance device fits the patient's ear. The heart rate sensor data provides quantitative feedback that indicates how well the hearing assistance device fits the patient's ear. The heart rate sensor data may be used to provide an indication to the patient to reseat or otherwise adjust the fitting of the hearing assistance device. The improved fitting process provides the ability for the audiologist and patient to identify a preferred or optimized hearing assistance device geometry. This improved fit provides improved performance and reliability of the hearing assistance device.

Abstract: Embodiment provides a terminal which comprises at least one processor. The at least one processor is configured to: obtain first biometric feature information of a measured target, where the first biometric feature information includes a pulse wave signal and/or an electrocardio signal of the measured target; obtain a first status of the measured target according to the first biometric feature information of the measured target; determine blood pressure calculation policy of the measured target according to the first status of the measured target; and determine a blood pressure value of the measured target according to the blood pressure calculation policy and the first biometric feature information of the measured target.

Abstract: In some instances, a person may need monitoring. The monitoring may be based on age, or on other factors such as abilities and functionality. The monitoring may enable a supervising person to remotely receive updates regarding the subject person. The supervising person may enter in various biometric parameters to monitor. The supervising person may alternatively and/or additionally set other factors to monitor such as time of day, location, activity level, and the like. The monitoring may provide peace of mind to a supervising person to ensure the subject person is safe. In some embodiments, the supervising person may set various alarm thresholds. The alarm thresholds may trigger an alert to the supervising person. In alternative embodiments, if the subject person is a grown person without a supervising person in the same vicinity, a security and/or automation system may act as the supervising adult.

Abstract: Certain aspects of the disclosure are directed to an apparatus including a scale and external circuitry. The scale includes a platform, and data-procurement circuitry for collecting signals indicative of the user's identity and cardio-physiological measurements. The scale includes processing circuitry to process data obtained by the data-procurement circuitry, therefrom generate cardio-related physiologic data, and to send user data to the external circuitry. The external circuitry identifies a risk that the user has a condition based on the reference information and the user data provided by the scale and outputs generic information correlating to the condition to the scale that is tailored based on the identified risk.

Abstract: A system and method are provided for performing operations comprising: receiving one or more images from an image capture device of a medical treatment location; applying a trained machine learning model to the one or more images to detect presence of a patient in the medical treatment location, the trained machine learning model being trained to establish a relationship between one or more features of images of the medical treatment location and patient presence; generating context assessment for the medical treatment location based on the detected presence of the patient; and transmitting, over a network, the context assessment for presentation on a user interface of a client device.

Abstract: A system for acoustically monitoring a heartbeat includes an acoustic body having a first material in contact with a second material, a density and a propagation speed of sound of the first material is matched with a density and a propagation speed of sound of a human body, and a density and a propagation speed of sound of the second material is matched with the density and the propagation speed of sound of the first material, a covering material in contact with a first surface of the acoustic body formed by the first material, and a microphone acoustically coupled to a second surface of the acoustic body formed by the second material.

Abstract: A method and an assembly for securing a crimped medical device over a deflated balloon of a balloon catheter is provided. The medical device is positioned in its expanded state over the deflated balloon of the balloon catheter, and is then crimped over the deflated balloon. First and second eyelets of first and second strings, respectively, are then threaded through first and second rings, respectively, that are provided on the medical device. Next, a locking wire is advanced through a lumen defined between the sheath and the catheter body to exit the distal end of the sheath, and then advanced through the first and second eyelets and into the distal tip of the balloon catheter. The sheath is then advanced over the crimped medical device to the distal tip to completely cover the crimped medical device.

Abstract: A biological signal of a subject is acquired so as to calculate biological information from the acquired biological signal. When the biological information has been determined to be anomaly, whether the biological information is one that was calculated under a high-accuracy condition is determined. When the biological information is determined to be one that was calculated under the high-accuracy condition, a notice is given based on a first criterion. In the other cases, a notice is given based on a second criterion. Thereby, it is possible to provide an abnormality notification system that can give a necessary notification appropriately while suppressing unnecessary notification, by changing the criteria for notification in accordance with the accuracy of the determined biological information when the biological information of the subject was determined to be anomaly.

Abstract: Disclosed are systems, methods, and non-transitory computer-readable media for clock synchronization in half-duplex communication systems. Devices in a half-duplex system are synchronized based on time stamp values captured by each device that define a specified period of time that is of equal in length. The specified period of time spans two change-over periods to average the jitter and/or drift that occurs during each period. Each device uses these measured lengths to determine the variance in the rates at which the two internal clocks operates, which is then used to synchronizes the internal clocks of the two devices.

Abstract: A user interface for clinical personnel provides selectable views of a plurality of medical risk scores. Questions whose answers are needed for calculation of those risk scores are asked in a question and answer area of the user interface, which allows some questions to be answered based on real time patient physiological data streams that are overridable by user provided answers. Where multiple risk score calculations require answers to the same question, the user provided answer may be supplied as an answer to the corresponding question for each risk score, rather than requiring the user to answer multiple times. Sparklines may be provided with the displayed risk scores to show trends in the risk score values, and may be updated in real time based on real time physiological data streams. The display of risk scores may visually distinguish between risk scores that have been validated and those are based on unvalidated answers to the questions.

Abstract: A system and method for non-invasively monitoring the hemodynamic state of a patient by determining on a beat-by-beat basis the ratio of lusitropic function to inotropic function as an index of myocardial well-being or pathology for use by clinicians in the hospital or by the patient at home. In one embodiment of the system a smartphone running an application program that is connected through the internet to the cloud processes electronic signals, first, from an electrocardiogram device monitoring electrical cardiac activity, and second, from a seismocardiogram device monitoring mechanical cardiac activity in order to determine such ratio as an instantaneous measurement of the hemodynamic state of the patient, including such states as sepsis, myocardial ischemia, and heart failure.

Abstract: Various embodiments described herein provide for operation of a memory sub-system based on a profile (also referred to herein as an operational profile) that causes the memory sub-system to have a specific set of operational characteristics. Additionally, some embodiments can provide dynamic switching between profiles based on a set of conditions being satisfied, such as current time of day or detection of a particular data input/out (I/O) pattern with respect to the memory sub-system.

Abstract: A medication dispensing system, data-enabled medication box holder, and methods for reminding, monitoring, tracking, and/or communicating dose events are disclosed. The data-enabled medication box holder holds a medication box for dispensing medication packets, each of which is tagged with machine-readable medium, wherein the machine-readable medium indicates the contents of the medication packet. The data-enabled medication box holder includes electronics for processing and communicating information about valid dose events and/or dose exception events. Further, a medication adherence system for and method of monitoring a patient's medication adherence and facilitating dose reminder notifications is disclosed. The medication adherence system includes a centralized server for collecting and processing the patient-specific information from the data-enabled medication box holders.

Abstract: A wireless circuit includes a housing, such as a hermetic housing, and at least one antenna coil wound about a coil axis within the housing. The coil axis may be substantially parallel to at least one wall of the housing, wherein the wall parallel to the coil axis is substantially thinner than other walls of the housing.

Abstract: In a method and apparatus for supporting preparation of a patient for a medical imaging investigation, in particular a magnetic resonance investigation, patient data of a patient are acquired by operation of an acquisition unit. An item of position information of an object is calculated by a calculation computer, the calculation of the position information of the object taking place on the basis of the patient data and/or on the basis of an item of investigation information and/or on the basis of data from accessory units. The position information of the object is projected by means of a projection unit.

Abstract: A materialized view created by a materialized view management platform may be replicated across many different target systems. The materialized view management platform allows users to specify different target systems. To create the materialized view in the different target systems, the materialized view management platform can translate the materialized view into different formats in order to store the materialized view in the different formats. Updates to the different instances of the materialized view are then made to keep the different materialized view formats in the different target systems up-to-date.

Abstract: Methods, apparatus, and systems for medical procedures include a monitoring and processing apparatus that includes a memory configured to store a diagnostic algorithm, a sensor configured to sense a patient data of a first patient, a processor configured to generate a first diagnostic result based on the patient data and the diagnostic algorithm. A local computing device is provided and includes a processor configured to receive the first diagnostic result via a first network, receive a first correction indication that includes a correction of the first diagnostic result and transmit the first correction indication via a second network. A remote computing device may be provided and be configured to generate an updated diagnostic algorithm that is updated based on the first correction indication and transmit the updated diagnostic algorithm via the second network.

Abstract: A task processor has a low power connectivity processor and a high performance applications processor. Software processes have a component operative on a connectivity processor and a component operative on an applications processor. The low power connectivity processor is coupled to a low power front end for wireless packets and the high performance applications processor is coupled to a high performance front end. A power controller is coupled to the low power front end and enables the applications processor and high performance front end when wireless packets which require greater processing capacity are received, and removes power from the applications processor and high performance front end at other times.

Abstract: A method, computing platform, and computer program product are provided for monitoring a clinical trial. A computer platform receives, for the clinical trial, study design information including a set of parameters and corresponding parameter values related to travel constraints of a subject for the clinical trial. The computer platform applies the study design information and the corresponding parameter values to a trained machine learning model to calculate a predicted travel score indicative of a travel burden for the subject. When the travel score fails to satisfy a travel score threshold, the computer platform determines at least one suggestion for adjusting the travel score and the at least one suggestion is output. The computer platform outputs the predicted travel score.

Abstract: It is possible that an analyzer may be operated such that it may perform tests to identify the presence or absence of a specified condition. Such tests may be performed using behaviors which are specific to the specified condition, and the results of those tests may be presented in a single output.

Abstract: System and method for recipe discovery and consumption logging. Improved solutions enable intelligent management of a user's personal fitness journey i.e., based on their overall health in their exercise and dietary habits. In one exemplary embodiment, recipes may be curated and tagged from a variety of sources such as health and fitness blogs and/or other articles of interest. Recipe tagging ensures that users can retrieve only the specific recipes of interest to them from a variety of sources which may be focused on the public at large. Additionally, the recipe discovery and consumption logging interface may enable users to log actual consumption activity for a selected recipe, including ad hoc user modifications to recipe ingredients.